Aliases & Classifications for Gait Apraxia

MalaCards integrated aliases for Gait Apraxia:

Name: Gait Apraxia 12 30 45 15 17 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4260
MeSH 45 D020235
SNOMED-CT 69 30767006
UMLS 74 C1510417

Summaries for Gait Apraxia

MalaCards based summary : Gait Apraxia is related to apraxia and hydrocephalus, and has symptoms including gait ataxia, waddling gait and gait dyspraxia. An important gene associated with Gait Apraxia is SLC25A20 (Solute Carrier Family 25 Member 20). The drugs Ergocalciferol and Vitamin D have been mentioned in the context of this disorder. Affiliated tissues include brain and bone, and related phenotypes are nervous system and liver/biliary system

Related Diseases for Gait Apraxia

Graphical network of the top 20 diseases related to Gait Apraxia:



Diseases related to Gait Apraxia

Symptoms & Phenotypes for Gait Apraxia

UMLS symptoms related to Gait Apraxia:


gait ataxia, waddling gait, gait dyspraxia

MGI Mouse Phenotypes related to Gait Apraxia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 nervous system MP:0003631 9.63 APP CBSL CDKL5 GRN MECP2 SLC25A20
2 liver/biliary system MP:0005370 9.56 CBSL GRN MECP2 SLC25A20
3 no phenotypic analysis MP:0003012 9.26 APP CDKL5 GRN MECP2
4 vision/eye MP:0005391 8.92 CBSL CDKL5 GRN MECP2

Drugs & Therapeutics for Gait Apraxia

Drugs for Gait Apraxia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ergocalciferol Approved, Nutraceutical 50-14-6 5280793
2
Vitamin D Approved, Nutraceutical, Vet_approved 1406-16-2
3
Calcium Approved, Nutraceutical 7440-70-2 271
4 Calciferol
5 Bone Density Conservation Agents
6 Ergocalciferols
7 Vitamin D2
8 Hormones
9 Nutrients
10 Trace Elements
11 Vitamins
12 Micronutrients
13 Calcium, Dietary

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Evaluation of the Efficacy, Safety, and Tolerability of Sarizotan in Rett Syndrome With Respiratory Symptoms Active, not recruiting NCT02790034 Phase 2, Phase 3 Sarizotan;Placebo
2 Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia Unknown status NCT00494689
3 Study of Adherence and Effects of Balance Exercices (SIEL BLEU Associatio) Unknown status NCT01314638
4 Alzheimer's Disease and Related Disorders Unknown status NCT01315704 Drug intervention
5 Gait and Alzheimer Interaction Tracking (GAIT) Study Completed NCT01315717
6 Gait as Predictor of Dementia and Falls. The Gait and Brain Cohort Study Recruiting NCT03020381

Search NIH Clinical Center for Gait Apraxia

Cochrane evidence based reviews: gait apraxia

Genetic Tests for Gait Apraxia

Genetic tests related to Gait Apraxia:

# Genetic test Affiliating Genes
1 Gait Apraxia 30

Anatomical Context for Gait Apraxia

MalaCards organs/tissues related to Gait Apraxia:

42
Brain, Bone

Publications for Gait Apraxia

Articles related to Gait Apraxia:

(show all 18)
# Title Authors Year
1
Balance impairment does not necessarily coexist with gait apraxia in mild and moderate Alzheimer's disease. ( 27332069 )
2016
2
A second case of isolated gait apraxia from an acute unilateral parasagittal lesion. ( 22560156 )
2012
3
Isolated gait apraxia from an acute unilateral parasagittal lesion. ( 21880413 )
2011
4
Gait apraxia. ( 20429324 )
2010
5
Gait apraxia in multiple sclerosis. ( 19831123 )
2009
6
Gait and dementia: moving beyond the notion of gait apraxia. ( 17510733 )
2007
7
Gait apraxia: further clues to localization. ( 17622719 )
2007
8
Walking difficulties in patients with Alzheimer's disease might originate from gait apraxia. ( 14742586 )
2004
9
Gait apraxia after bilateral supplementary motor area lesion. ( 11784830 )
2002
10
Frontal gait apraxia. Pathophysiological mechanisms and rehabilitation. ( 11347240 )
2001
11
A SPECT study of patients with gait apraxia without evidence of frontal lobe dysfunction. ( 9614780 )
1998
12
Gait apraxia and headache. ( 8370100 )
1993
13
L-threo-3,4-dihydroxyphenylserine treatment for gait apraxia in parkinsonian patients. ( 2511378 )
1989
14
Risk factors for the syndrome of ventricular enlargement with gait apraxia (idiopathic normal pressure hydrocephalus): a case-control study. ( 2769278 )
1989
15
Gait apraxia in normal-pressure hydrocephalus: patterns of movement and muscle activation. ( 3969202 )
1985
16
Parkinsonism, gait apraxia and dementia associated with intracranial calcifications. A case report. ( 6845088 )
1983
17
Gait apraxia in communicating hydrocephalus. ( 7241157 )
1981
18
Intracranial calcification in hyperparathyroidism associated with gait apraxia and parkinsonism. ( 7191528 )
1980

Variations for Gait Apraxia

Expression for Gait Apraxia

Search GEO for disease gene expression data for Gait Apraxia.

Pathways for Gait Apraxia

GO Terms for Gait Apraxia

Biological processes related to Gait Apraxia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 learning GO:0007612 9.32 APP MECP2
2 adult locomotory behavior GO:0008344 9.26 APP MECP2
3 visual learning GO:0008542 9.16 APP MECP2
4 dendrite development GO:0016358 8.96 APP MECP2
5 positive regulation of G2/M transition of mitotic cell cycle GO:0010971 8.62 APP MECP2

Sources for Gait Apraxia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....