MCID: GLL051
MIFTS: 22

Gallbladder Benign Neoplasm

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gallbladder Benign Neoplasm

MalaCards integrated aliases for Gallbladder Benign Neoplasm:

Name: Gallbladder Benign Neoplasm 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0080640
NCIt 49 C4440

Summaries for Gallbladder Benign Neoplasm

Disease Ontology : 12 A biliary tract benign neoplasm that is located in the gallbladder.

MalaCards based summary : Gallbladder Benign Neoplasm is related to gallbladder adenoma and gallbladder lipoma. An important gene associated with Gallbladder Benign Neoplasm is NIPSNAP2 (Nipsnap Homolog 2), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and MAPK Erk Pathway. Affiliated tissues include gallbladder, and related phenotype is cardiovascular system.

Related Diseases for Gallbladder Benign Neoplasm

Diseases related to Gallbladder Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 213)
# Related Disease Score Top Affiliating Genes
1 gallbladder adenoma 30.8 PPARA PDPN NIPSNAP2 LFNG KRT7 ATP5F1B
2 gallbladder lipoma 11.4
3 colonic lymphangioma 10.2 PDPN KRT7
4 eccrine papillary adenocarcinoma 10.2 PDPN KRT7
5 bladder lateral wall cancer 10.2 PDPN KRT7
6 benign peritoneal mesothelioma 10.1 PDPN KRT7
7 signet ring basal cell carcinoma 10.1 KRAS HRAS
8 trachea carcinoma in situ 10.1 KRAS HRAS
9 cobblestone retinal degeneration 10.1 KRAS HRAS
10 ampulla of vater neoplasm 10.1 KRAS HRAS
11 descending colon cancer 10.1 KRAS HRAS
12 periampullary adenoma 10.1 KRAS HRAS
13 adenosquamous lung carcinoma 10.1 KRAS HRAS
14 acneiform dermatitis 10.1 KRAS HRAS
15 myh-associated polyposis 10.0 KRAS HRAS
16 mucinous lung adenocarcinoma 10.0 KRAS HRAS
17 ascending colon cancer 10.0 KRAS HRAS
18 pancreatic acinar cell adenocarcinoma 10.0 KRAS HRAS
19 core binding factor acute myeloid leukemia 10.0 KRAS HRAS
20 apocrine adenoma 10.0 KRT7 KRAS
21 lung carcinoma in situ 10.0 KRAS HRAS
22 vaginal tubulovillous adenoma 10.0 KRT7 KRAS
23 sigmoid neoplasm 10.0 KRT7 KRAS
24 paronychia 10.0 KRAS HRAS
25 mucinous cystadenocarcinoma 10.0 PDPN KRT7
26 pulmonary adenocarcinoma in situ 10.0 KRAS HRAS
27 ovarian mucinous neoplasm 10.0 KRT7 KRAS
28 penile benign neoplasm 10.0 TP53 PDPN
29 xanthogranulomatous cholecystitis 10.0 TP53 PDPN
30 oculoectodermal syndrome 10.0 KRAS HRAS
31 myasthenic syndrome, congenital, 14 10.0 KRAS HRAS
32 conjunctival squamous cell carcinoma 10.0 TP53 PDPN
33 lung non-squamous non-small cell carcinoma 10.0 KRAS HRAS
34 rectosigmoid cancer 9.9 KRAS HRAS
35 struma ovarii 9.9 KRT7 KRAS
36 gallbladder disease 1 9.9
37 adenoma 9.9
38 prostate squamous cell carcinoma 9.9 TP53 HRAS
39 keratocystic odontogenic tumor 9.9 TP53 PDPN
40 spitz nevus 9.9 TP53 HRAS
41 adult teratoma 9.9 TP53 HRAS
42 lip cancer 9.9 TP53 PDPN
43 squamous cell papilloma 9.9 TP53 HRAS
44 laryngeal benign neoplasm 9.9 TP53 PDPN
45 pulmonic stenosis 9.9 KRAS HRAS
46 pancreatic foamy gland adenocarcinoma 9.9 TP53 KRT7
47 adult malignant schwannoma 9.9 TP53 HRAS
48 ovarian seromucinous carcinoma 9.9 TP53 KRT7
49 intratubular embryonal carcinoma 9.9 TP53 KRT7
50 necrotizing sialometaplasia 9.9 TP53 KRT7

Graphical network of the top 20 diseases related to Gallbladder Benign Neoplasm:



Diseases related to Gallbladder Benign Neoplasm

Symptoms & Phenotypes for Gallbladder Benign Neoplasm

MGI Mouse Phenotypes related to Gallbladder Benign Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.17 HRAS KRAS LFNG PDPN PFN1 PPARA

Drugs & Therapeutics for Gallbladder Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Gallbladder Benign Neoplasm

Genetic Tests for Gallbladder Benign Neoplasm

Anatomical Context for Gallbladder Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Gallbladder Benign Neoplasm:

19
Gallbladder

Publications for Gallbladder Benign Neoplasm

Variations for Gallbladder Benign Neoplasm

Expression for Gallbladder Benign Neoplasm

Search GEO for disease gene expression data for Gallbladder Benign Neoplasm.

Pathways for Gallbladder Benign Neoplasm

Pathways related to Gallbladder Benign Neoplasm according to GeneCards Suite gene sharing:

(show all 27)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.05 TP53 PFN1 PDPN KRAS HRAS
2
Show member pathways
12.64 PPARA PFN1 KRAS HRAS
3 12.14 TP53 KRAS HRAS
4 12.09 TP53 KRAS HRAS
5 12.08 TP53 KRAS HRAS
6
Show member pathways
12.06 TP53 KRAS HRAS
7
Show member pathways
11.92 TP53 KRAS HRAS
8 11.88 TP53 KRAS HRAS
9
Show member pathways
11.84 TP53 KRAS HRAS
10
Show member pathways
11.81 TP53 KRAS HRAS
11
Show member pathways
11.78 TP53 KRAS HRAS
12 11.69 TP53 KRAS HRAS
13 11.62 TP53 KRAS HRAS
14 11.56 TP53 KRAS HRAS
15 11.48 TP53 KRAS HRAS
16 11.2 TP53 KRAS HRAS
17 11.15 KRAS HRAS
18 11.1 KRAS HRAS
19 11.09 KRAS HRAS
20
Show member pathways
11.07 KRAS HRAS
21
Show member pathways
11.01 KRAS HRAS
22 10.98 TP53 KRAS HRAS
23 10.92 KRAS HRAS
24 10.89 KRAS HRAS
25 10.83 KRAS HRAS
26 10.63 TP53 KRAS HRAS
27 10.52 KRAS HRAS

GO Terms for Gallbladder Benign Neoplasm

Biological processes related to Gallbladder Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intrinsic apoptotic signaling pathway GO:0097193 9.4 TP53 HRAS
2 cellular response to gamma radiation GO:0071480 9.37 TP53 HRAS
3 cell aging GO:0007569 9.32 TP53 HRAS
4 regulation of long-term neuronal synaptic plasticity GO:0048169 9.26 KRAS HRAS
5 positive regulation of ruffle assembly GO:1900029 9.16 PFN1 HRAS
6 response to isolation stress GO:0035900 8.96 KRAS HRAS
7 Ras protein signal transduction GO:0007265 8.8 TP53 KRAS HRAS

Molecular functions related to Gallbladder Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MDM2/MDM4 family protein binding GO:0097371 8.62 TP53 PPARA

Sources for Gallbladder Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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