MCID: GLL016
MIFTS: 25

Gallbladder Leiomyosarcoma

Categories: Cancer diseases, Gastrointestinal diseases, Muscle diseases

Aliases & Classifications for Gallbladder Leiomyosarcoma

MalaCards integrated aliases for Gallbladder Leiomyosarcoma:

Name: Gallbladder Leiomyosarcoma 12 15 70
Leiomyosarcoma of the Gallbladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5275
NCIt 50 C5841
UMLS 70 C1333746

Summaries for Gallbladder Leiomyosarcoma

Disease Ontology : 12 A gallbladder sarcoma that is located in the soft tissues of the gallbladder.

MalaCards based summary : Gallbladder Leiomyosarcoma, also known as leiomyosarcoma of the gallbladder, is related to leiomyosarcoma and urethra leiomyoma. An important gene associated with Gallbladder Leiomyosarcoma is CALD1 (Caldesmon 1), and among its related pathways/superpathways is NF-kappaB Signaling. Affiliated tissues include soft tissues of the gallbladder, breast and liver, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Gallbladder Leiomyosarcoma

Diseases related to Gallbladder Leiomyosarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 236)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 30.6 PECAM1 MB KIT
2 urethra leiomyoma 10.2 KIT CALD1
3 gallbladder disease 1 10.2
4 cholelithiasis 10.2
5 cholecystitis 10.2
6 prostate embryonal rhabdomyosarcoma 10.2 KIT CALD1
7 gastric leiomyoma 10.2 KIT CALD1
8 glomus tumor 10.2 CD34 CALD1
9 breast myofibroblastoma 10.2 CD34 CALD1
10 pulmonary vein leiomyosarcoma 10.2 CD34 CALD1
11 glomangiomyoma 10.2 CD34 CALD1
12 vulvar leiomyosarcoma 10.2 CD34 CALD1
13 peritoneal benign neoplasm 10.2 CD34 CALD1
14 spinal cord sarcoma 10.2 KIT CD34
15 gallbladder leiomyoma 10.2 KIT CD34
16 mediastinum seminoma 10.2 KIT AFP
17 adult fibrosarcoma 10.2 CD34 CALD1
18 cervical polyp 10.2 CD34 CALD1
19 mixed germ cell tumor 10.2 KIT AFP
20 small intestine leiomyosarcoma 10.2 KIT CD34
21 neuronal intestinal dysplasia, type b 10.2 KIT CD34
22 intravenous leiomyomatosis 10.2 CD34 CALD1
23 gastric liposarcoma 10.2 KIT CD34
24 extragonadal seminoma 10.2 KIT AFP
25 mucocele of appendix 10.2 KIT CD34
26 pleomorphic liposarcoma 10.2 KIT CALD1
27 congenital granular cell tumor 10.2 CD34 CALD1
28 pineal region teratoma 10.2 KIT AFP
29 cutaneous leiomyosarcoma 10.2 CD34 CALD1
30 benign fibrous mesothelioma 10.1 KIT CD34
31 infiltrating angiolipoma 10.1 CD34 CALD1
32 liver fibroma 10.1 KIT CD34
33 perivascular epithelioid cell tumor 10.1 KIT CALD1
34 jejunal neoplasm 10.1 KIT CD34
35 extraosseous osteosarcoma 10.1 CD34 CALD1
36 intratubular embryonal carcinoma 10.1 KIT AFP
37 adenosarcoma 10.1 MB KIT
38 esophageal adenoid cystic carcinoma 10.1 KIT AFP
39 plexiform schwannoma 10.1 KIT CD34
40 mixed germ cell cancer 10.1 KIT AFP
41 ovarian mixed germ cell neoplasm 10.1 KIT AFP
42 cutaneous ganglioneuroma 10.1 KIT CD34
43 cervical adenosarcoma 10.1 CD34 CALD1
44 breast malignant phyllodes tumor 10.1 KIT CD34
45 nasal cavity benign neoplasm 10.1 KIT CD34
46 prostate stromal sarcoma 10.1 KIT CD34
47 endometrial small cell carcinoma 10.1 KIT AFP
48 dysgerminoma 10.1 KIT AFP
49 dysgerminoma of ovary 10.1 KIT AFP
50 germinoma 10.1 KIT AFP

Graphical network of the top 20 diseases related to Gallbladder Leiomyosarcoma:



Diseases related to Gallbladder Leiomyosarcoma

Symptoms & Phenotypes for Gallbladder Leiomyosarcoma

GenomeRNAi Phenotypes related to Gallbladder Leiomyosarcoma according to GeneCards Suite gene sharing:

26 (show all 11)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-1 9.36 PECAM1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-114 9.36 AFP
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-120 9.36 AFP
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-15 9.36 KRT19
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-198 9.36 PECAM1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-2 9.36 PECAM1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-29 9.36 AFP
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-63 9.36 AFP
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.36 AFP
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-75 9.36 AFP
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.36 PECAM1

MGI Mouse Phenotypes related to Gallbladder Leiomyosarcoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.92 AFP CD34 KIT KRT19

Drugs & Therapeutics for Gallbladder Leiomyosarcoma

Search Clinical Trials , NIH Clinical Center for Gallbladder Leiomyosarcoma

Genetic Tests for Gallbladder Leiomyosarcoma

Anatomical Context for Gallbladder Leiomyosarcoma

The Foundational Model of Anatomy Ontology organs/tissues related to Gallbladder Leiomyosarcoma:

19
Soft Tissues Of The Gallbladder

MalaCards organs/tissues related to Gallbladder Leiomyosarcoma:

40
Breast, Liver, Skin, Heart, Small Intestine, Prostate, Thymus

Publications for Gallbladder Leiomyosarcoma

Articles related to Gallbladder Leiomyosarcoma:

(show all 23)
# Title Authors PMID Year
1
Primary Leiomyosarcoma of the Gallbladder. 61
32670649 2020
2
Leiomyosarcoma of the gallbladder-A case report and a review of literature. 61
31864148 2020
3
Primary leiomyosarcoma of gallbladder. 61
23230561 2012
4
Primary leiomyosarcoma of gallbladder: a rare diagnosis. 61
22900213 2012
5
Primary leiomyosarcoma of the gallbladder. 61
20187695 2010
6
[Leiomyosarcoma of the gallbladder]. 61
18771866 2008
7
Polypoid leiomyosarcoma of the gallbladder: study of a case associated with adenomyomatous hyperplasia. 61
15614741 2004
8
[Primary leiomyosarcoma of the gallbladder]. 61
15259151 2004
9
Leiomyosarcoma of the gallbladder: a case report. 61
11565767 2001
10
Leiomyosarcoma of the gallbladder--a case report and review of the literature. 61
9636020 1998
11
[Leiomyosarcoma of the gallbladder]. 61
8705495 1996
12
[Leiomyosarcoma of the gallbladder: a clinical case]. 61
8136239 1993
13
[Primary leiomyosarcoma of the gallbladder]. 61
1419331 1992
14
Primary leiomyosarcoma of the gallbladder. Case report and review of the literature. 61
2278917 1990
15
[A case of leiomyosarcoma of the gallbladder]. 61
2201806 1990
16
[Gigantic leiomyosarcoma of the gallbladder]. 61
2803031 1989
17
[Primary leiomyosarcoma of the gallbladder]. 61
3187158 1988
18
[Leiomyosarcoma of the gallbladder]. 61
3662851 1987
19
Primary leiomyosarcoma of gallbladder seen on computed tomography and ultrasound. 61
3513545 1986
20
[Malignant leiomyosarcoma of the gallbladder]. 61
3831874 1985
21
Leiomyosarcoma of the gallbladder. 61
5277472 1971
22
[LEIOMYOSARCOMA OF THE GALLBLADDER]. 61
14124476 1963
23
[On a case of leiomyosarcoma of the gallbladder]. 61
13721647 1960

Variations for Gallbladder Leiomyosarcoma

Expression for Gallbladder Leiomyosarcoma

Search GEO for disease gene expression data for Gallbladder Leiomyosarcoma.

Pathways for Gallbladder Leiomyosarcoma

Pathways related to Gallbladder Leiomyosarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.31 PECAM1 KIT CD34

GO Terms for Gallbladder Leiomyosarcoma

Biological processes related to Gallbladder Leiomyosarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glomerular endothelium development GO:0072011 8.62 PECAM1 CD34

Sources for Gallbladder Leiomyosarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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