MCID: GLL013
MIFTS: 32

Gallbladder Lymphoma

Categories: Blood diseases, Cancer diseases, Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Gallbladder Lymphoma

MalaCards integrated aliases for Gallbladder Lymphoma:

Name: Gallbladder Lymphoma 12 15 71
Lymphoma of the Gallbladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8135
NCIt 50 C5734
UMLS 71 C1333748

Summaries for Gallbladder Lymphoma

MalaCards based summary : Gallbladder Lymphoma, also known as lymphoma of the gallbladder, is related to intravascular large b-cell lymphoma and plasmablastic lymphoma. An important gene associated with Gallbladder Lymphoma is MALT1 (MALT1 Paracaspase), and among its related pathways/superpathways are Innate Immune System and IL-2 Pathway. Affiliated tissues include myeloid, skin and testis, and related phenotypes are hematopoietic system and cellular

Related Diseases for Gallbladder Lymphoma

Diseases related to Gallbladder Lymphoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 200)
# Related Disease Score Top Affiliating Genes
1 intravascular large b-cell lymphoma 30.3 MME CD5 BCL6
2 plasmablastic lymphoma 30.1 PTPRC BCL6
3 pleural empyema 30.1 TNFRSF8 CD79A BCL6
4 nodal marginal zone lymphoma 29.8 SPN MME IRF4 CD5 BCL6
5 lymphoma, hodgkin, classic 29.4 TNFRSF8 PTPRC PAX5 IRF4 BCL6
6 peripheral t-cell lymphoma 29.2 TNFRSF8 PTPRC MME CD5 CCND1 BCL6
7 follicular lymphoma 28.8 MME IRF4 FCER2 CR2 CD5 CCND1
8 burkitt lymphoma 28.5 TNFRSF8 SOX11 PAX5 MME IRF4 FCER2
9 lymphoma 28.2 TNFRSF8 PTPRC PAX5 MALT1 IRF4 CR2
10 lymphoma, mucosa-associated lymphoid type 27.9 TNFRSF8 SPN PTPRC PAX5 MME MALT1
11 marginal zone b-cell lymphoma 27.7 TNFRSF8 SPN PAX5 MME MALT1 IRF4
12 diffuse large b-cell lymphoma 27.5 TNFRSF8 SPN PTPRC PAX5 MME MALT1
13 b-cell lymphoma 27.5 TNFRSF8 PTPRC PAX5 MME MALT1 IRF4
14 lymphoma, non-hodgkin, familial 27.2 TNFRSF8 SPN PTPRC PAX5 MME MALT1
15 leukemia, acute myeloid 27.1 TNFRSF8 SPN PTPRC PAX5 MME FUT4
16 nodal marginal zone b-cell lymphoma 10.4 MALT1 BCL6
17 orbit lymphoma 10.4 MALT1 BIRC3
18 chest wall lymphoma 10.4 MME BCL6
19 ovarian lymphoma 10.4 MME BCL6
20 fallopian tube endometriosis 10.4 MME CEACAM5
21 endocrine exophthalmos 10.4 MME CD5
22 hilar lung carcinoma 10.4 MME CD79A
23 lung hilum cancer 10.4 MME CD79A
24 thymus adenocarcinoma 10.4 CEACAM5 CD5
25 cervical serous adenocarcinoma 10.4 MME CEACAM5
26 mucocele of appendix 10.4 MME CEACAM5
27 eye lymphoma 10.4 CD5 BCL6
28 papillary thymic adenocarcinoma 10.4 CEACAM5 CD5
29 pancreatic serous cystadenocarcinoma 10.4 MME CEACAM5
30 female urethral cancer 10.4 MME CEACAM5
31 liver lymphoma 10.4 MME CD79A
32 atrophoderma vermiculata 10.4 MME CEACAM5
33 lymphohistiocytoid mesothelioma 10.3 CEACAM5 CD5
34 ovarian mixed germ cell neoplasm 10.3 MME CEACAM5
35 clear cell hidradenoma 10.3 MME CEACAM5
36 b cell prolymphocytic leukemia 10.3 FCER2 CD5
37 liver inflammatory pseudotumor 10.3 CR2 CEACAM5
38 pancreatic mucinous cystadenoma 10.3 MME CEACAM5
39 squamous papillomatosis 10.3 MME CEACAM5
40 central nervous system leukemia 10.3 MME CD33
41 orofaciodigital syndrome viii 10.3 MALT1 BIRC3 BCL6
42 subacute lymphocytic thyroiditis 10.3 CR2 BIRC3
43 cutaneous adenocystic carcinoma 10.3 MME CEACAM5
44 leukemia, chronic lymphocytic 2 10.3 FCER2 CD5
45 liver leiomyoma 10.3 CR2 CEACAM5
46 monoclonal paraproteinemia 10.3 PAX5 CD79A
47 prostate lymphoma 10.3 MME CD5 BCL6
48 nodular lymphocyte predominant hodgkin lymphoma 10.3 CCND1 BCL6
49 nasal cavity olfactory neuroblastoma 10.3 MME CEACAM5
50 appendix lymphoma 10.3 MME CD5 BCL6

Graphical network of the top 20 diseases related to Gallbladder Lymphoma:



Diseases related to Gallbladder Lymphoma

Symptoms & Phenotypes for Gallbladder Lymphoma

MGI Mouse Phenotypes related to Gallbladder Lymphoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.13 BCL6 BIRC3 CCND1 CD5 CD79A CR2
2 cellular MP:0005384 10.06 BCL6 BIRC3 CCND1 CD79A FCER2 FUT4
3 immune system MP:0005387 10.06 BCL6 BIRC3 CCND1 CD5 CD79A CR2
4 neoplasm MP:0002006 9.43 CCND1 CD79A IRF4 PAX5 PTPRC SPN
5 normal MP:0002873 9.28 BCL6 BIRC3 CCND1 CD2 CD5 CD79A

Drugs & Therapeutics for Gallbladder Lymphoma

Search Clinical Trials , NIH Clinical Center for Gallbladder Lymphoma

Genetic Tests for Gallbladder Lymphoma

Anatomical Context for Gallbladder Lymphoma

MalaCards organs/tissues related to Gallbladder Lymphoma:

40
Myeloid, Skin, Testis

Publications for Gallbladder Lymphoma

Articles related to Gallbladder Lymphoma:

(show all 49)
# Title Authors PMID Year
1
Review on gall bladder myeloid sarcoma: a great masquerader. 61
32434344 2020
2
Unusual endoscopic ultrasonography presentation of gallbladder malignancy: Gallbladder lymphoma. 61
31665804 2020
3
Diffuse large B-cell lymphoma of the gallbladder arised 8 years after malignant lymphoma of the right testis: A case report and literature review. 61
33010608 2020
4
Incidental metastases and lymphoma of the gallbladder - an analysis of ten rare cases identified from a large national database. 61
31035806 2019
5
Intravascular Large B-Cell Lymphoma of the Gallbladder. 61
29391332 2018
6
[Gallbladder Malignant Lymphoma Diagnosed after Surgery for Acute Cholecystitis - A Case Report]. 61
29362316 2018
7
Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the gallbladder and review of the literature. 61
28551602 2017
8
Primary Non-Hodgkin's Lymphoma of the Gallbladder: A Population-based Analysis. 61
28476830 2017
9
An Unusual Case of Primary Extranodal Lymphoma of the Gallbladder. 61
28435654 2017
10
[Primary gastrointestinal lymphoma]. 61
28948797 2017
11
Synchronous Adenocarcinoma and Lymphoma of the Gallbladder: A Case Report. 61
26537793 2016
12
Plasmablastic lymphoma of the gallbladder. 61
27059870 2016
13
Primary gallbladder lymphoma presenting with perforated cholecystitis and hyperamylasaemia. 61
26673049 2016
14
[MALT lymphoma of the gallbladder]. 61
25113861 2015
15
Gallbladder lymphoma in a miniature dachshund. 61
25311915 2015
16
Primary Gallbladder Lymphoma in a Male Patient with No Risk Factors Detected Incidentally by CT Colonography. 61
26587306 2015
17
Primary gallbladder lymphoma presenting as a polyp. 61
24798355 2014
18
Primary lymphoma of the gallbladder accompanied by cirrhosis: CT and MRI findings. 61
24827653 2014
19
Postsurgical long-term disease-free survival in a case of primary diffuse large B-cell lymphoma of the gallbladder without adjuvant therapy. 61
24480203 2014
20
Primary gallbladder small lymphocytic lymphoma as a rare postcholecystectomy finding. 61
24891962 2014
21
[A case of malignant lymphoma of the gallbladder after chemotherapy for malignant lymphoma of the skin and right intraocular]. 61
22202407 2011
22
Gallbladder lymphoma. 61
20407853 2011
23
Primary gallbladder lymphoma. 61
21375853 2011
24
[Primary Burkitt's lymphoma of the gallbladder]. 61
20074718 2010
25
Excavated pulmonary nodules: an unusual clinical presentation of lung metastasis in two cases. 61
20576147 2010
26
Simultaneous occurrence of primary diffuse large B-cell lymphoma and extranodal marginal zone (MALT) B-cell lymphoma in the gallbladder: a case report. 61
20387709 2009
27
Primary mucosa-associated lymphoid tissue lymphoma of the gallbladder: report of a case harboring API2/MALT1 gene fusion. 61
19535128 2009
28
Ultrasonographic features of a large B-cell lymphoma of the gallbladder. 61
19821214 2009
29
Gallbladder lymphoma in primary sclerosing cholangitis. 61
18848908 2009
30
Primary malignant lymphoma of the gallbladder: a case report and literature review. 61
19095809 2009
31
Primary MALT lymphoma of the gallbladder. Case report. 61
18568144 2008
32
Primary non-Hodgkin's lymphoma of the gallbladder diagnosed by laparoscopic cholecystectomy. 61
18987940 2008
33
Primary diffuse large B-cell lymphoma of the gallbladder with cholelithiasis masquerading as acute cholecystitis: case report and literature review. 61
17384698 2007
34
Primary non-Hodgkin's lymphoma of the gallbladder. 61
15728033 2005
35
Primary, extranodal, follicular non-Hodgkin lymphoma of the gallbladder: case report and a review of the literature. 61
15101728 2004
36
[A case of malignant lymphoma of the gallbladder]. 61
14593886 2003
37
Follicular lymphoma of the gallbladder and extrahepatic bile ducts. 61
12596064 2003
38
Primary mucosa-associated lymphoid tissue lymphoma of the gallbladder. 61
11959069 2002
39
Primary low-grade MALT lymphoma of the gallbladder. 61
11844071 2001
40
The irreplaceable image: B-cell lymphoma of the gallbladder. 61
11602429 2001
41
Primary non-Hodgkin's lymphoma of the gall bladder. 61
11426613 2000
42
[Gallbladder lymphoma: a rare cause of jaundice]. 61
11139687 2000
43
Mucosa-associated lymphoid tissue type lymphoma of the gallbladder associated with acute myeloid leukemia. 61
10397085 1999
44
Low-grade B cell lymphoma of mucosa-associated lymphoid tissue (MALT) arising in the gallbladder. 61
10430312 1999
45
Primary lymphoma of the gallbladder; case report and review of the literature. 61
8855763 1996
46
[Malignant lymphoma of the gallbladder]. 61
8705466 1996
47
Primary lymphoma of the gallbladder. 61
8415351 1993
48
Malignant angioendotheliomatosis (Angiotropic lymphoma) of the gallbladder. 61
2117313 1990
49
[Primary malignant lymphoma of the gallbladder--a case report]. 61
3838506 1985

Variations for Gallbladder Lymphoma

Expression for Gallbladder Lymphoma

Search GEO for disease gene expression data for Gallbladder Lymphoma.

Pathways for Gallbladder Lymphoma

Pathways related to Gallbladder Lymphoma according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.79 TNFRSF8 PTPRC MME MALT1 IRF4 FCER2
2
Show member pathways
12.98 PTPRC MALT1 FCER2 CR2 CD79A CCND1
3
Show member pathways
12.33 PTPRC CR2 CD79A BCL6
4
Show member pathways
12.13 PTPRC MALT1 IRF4 CR2 CD79A BCL6
5 12.12 TNFRSF8 PTPRC PAX5 MALT1 IRF4 CEACAM5
6 11.73 IRF4 FCER2 CCND1 BCL6
7 11.63 MME FCER2 CR2 CD5 CD33 CD2
8 11.55 PAX5 CCND1 BIRC3
9 11.49 SPN PTPRC MME IRF4
10 11.43 PAX5 CR2 BCL6
11 11.38 IRF4 FCER2 BCL6
12 11.29 SPN PTPRC MME CEACAM5 CD79A CD5

GO Terms for Gallbladder Lymphoma

Cellular components related to Gallbladder Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 10.1 TNFRSF8 SPN SOX11 PTPRC MME FCER2
2 integral component of plasma membrane GO:0005887 9.86 SPN PTPRC MME FCER2 CEACAM5 CD5
3 membrane raft GO:0045121 9.55 PTPRC MME CD79A CD2 BIRC3
4 cell surface GO:0009986 9.5 SPN PTPRC MME FUT4 CEACAM5 CD33
5 external side of plasma membrane GO:0009897 9.17 SPN PTPRC FCER2 CD79A CD5 CD33

Biological processes related to Gallbladder Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.78 IRF4 FCER2 CCND1 BCL6
2 cell surface receptor signaling pathway GO:0007166 9.77 SPN PTPRC CD79A CD2 BIRC3
3 T cell activation GO:0042110 9.58 PTPRC IRF4 CD2
4 B cell proliferation GO:0042100 9.5 PTPRC CR2 CD79A
5 positive regulation of stem cell proliferation GO:2000648 9.46 SOX11 PTPRC
6 positive regulation of humoral immune response mediated by circulating immunoglobulin GO:0002925 9.43 PTPRC FCER2
7 positive regulation of interleukin-2 production GO:0032743 9.33 PTPRC MALT1 IRF4
8 positive regulation of protein tyrosine phosphatase activity GO:1903615 9.26 PTPRC CD33
9 positive regulation of tumor necrosis factor production GO:0032760 9.26 TNFRSF8 SPN PTPRC CD2
10 B cell differentiation GO:0030183 8.92 PTPRC CR2 CD79A BCL6

Molecular functions related to Gallbladder Lymphoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane signaling receptor activity GO:0004888 8.92 TNFRSF8 SPN CR2 CD79A

Sources for Gallbladder Lymphoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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