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MCID: GLL021
MIFTS: 23

Gallbladder Sarcoma

Categories: Cancer diseases, Gastrointestinal diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Gallbladder Sarcoma

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MalaCards integrated aliases for Gallbladder Sarcoma:

Name: Gallbladder Sarcoma 12 15 70
Malignant Mesenchymal Tumor of Gallbladder 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)


External Ids:

Disease Ontology 12 DOID:4058
NCIt 50 C5736
UMLS 70 C1333757
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Summaries for Gallbladder Sarcoma

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Disease Ontology : 12 A sarcoma that is located in the gallbladder.

MalaCards based summary : Gallbladder Sarcoma, also known as malignant mesenchymal tumor of gallbladder, is related to leiomyosarcoma and spindle cell sarcoma. An important gene associated with Gallbladder Sarcoma is MYOG (Myogenin), and among its related pathways/superpathways are Cytoskeleton remodeling Neurofilaments and Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include gallbladder.

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Related Diseases for Gallbladder Sarcoma

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Diseases related to Gallbladder Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 leiomyosarcoma 30.2 MYOG DES
2 spindle cell sarcoma 30.2 MYOG DES
3 malignant fibrous histiocytoma 29.8 MYOG MYOD1 DES
4 botryoid rhabdomyosarcoma 29.6 MYOG MYOD1 DES
5 rhabdomyosarcoma 29.6 MYOG MYOD1 DES
6 embryonal rhabdomyosarcoma 29.6 MYOG MYOD1 DES
7 gallbladder angiosarcoma 11.1
8 gallbladder rhabdomyosarcoma 11.0
9 gallbladder leiomyosarcoma 11.0
10 pineal region teratoma 10.2 MYOG MYOD1
11 conventional leiomyosarcoma 10.2 MYOG MYOD1
12 skeletal muscle neoplasm 10.2 MYOG MYOD1
13 prostate embryonal rhabdomyosarcoma 10.2 MYOG MYOD1
14 undifferentiated embryonal sarcoma of the liver 10.2 MYOG MYOD1
15 prostate rhabdomyosarcoma 10.2 MYOG MYOD1
16 central nervous system mesenchymal non-meningothelial tumor 10.2 MYOG MYOD1
17 adult fibrosarcoma 10.1 MYOG MYOD1
18 prostate stromal sarcoma 10.1 MYOG MYOD1
19 extraosseous ewing sarcoma 10.1 MYOG MYOD1
20 cervical adenosarcoma 10.1 MYOG MYOD1
21 breast rhabdomyosarcoma 10.1 MYOG MYOD1
22 gas gangrene 10.1 MYOG MYOD1
23 cervical polyp 10.1 MYOG DES
24 medullomyoblastoma 10.1 MYOG DES
25 ectomesenchymoma 10.1 MYOG DES
26 malignant fibrous histiocytoma of bone 10.1 MYOD1 DES
27 pleomorphic rhabdomyosarcoma 10.1 MYOG MYOD1
28 bilateral retinoblastoma 10.1 MYOG DES
29 emery-dreifuss muscular dystrophy 2, autosomal dominant 10.1 MYOG MYOD1
30 congenital fibrosarcoma 10.1 MYOG DES
31 pseudosarcomatous fibromatosis 10.1 MYOG DES
32 hemangiopericytoma, malignant 10.1 MYOG DES
33 sarcoma 10.1
34 skeletal muscle cancer 10.1 MYOG MYOD1
35 batten-turner congenital myopathy 10.1 MYOG DES
36 emery-dreifuss muscular dystrophy 10.0 MYOD1 DES
37 myxofibrosarcoma 10.0 MYOG DES
38 dedifferentiated liposarcoma 10.0 MYOG DES
39 angiosarcoma 10.0
40 cholecystitis 10.0
41 mesenchymal cell neoplasm 10.0
42 carcinosarcoma 10.0
43 fibrous histiocytoma 10.0
44 hemophagocytic lymphohistiocytosis, familial, 1 10.0 MYOG MYOD1
45 liposarcoma 10.0 MYOG DES
46 inflammatory leiomyosarcoma 9.9 MYOG MYOD1 DES
47 malignant triton tumor 9.9 MYOG MYOD1 DES
48 malignant mesenchymoma 9.9 MYOG MYOD1 DES
49 embryonal sarcoma 9.9 MYOG MYOD1 DES
50 spindle cell rhabdomyosarcoma 9.9 MYOG MYOD1 DES

Graphical network of the top 20 diseases related to Gallbladder Sarcoma:



Diseases related to Gallbladder Sarcoma
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Symptoms & Phenotypes for Gallbladder Sarcoma

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Drugs & Therapeutics for Gallbladder Sarcoma

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Search Clinical Trials , NIH Clinical Center for Gallbladder Sarcoma

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Genetic Tests for Gallbladder Sarcoma

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Anatomical Context for Gallbladder Sarcoma

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The Foundational Model of Anatomy Ontology organs/tissues related to Gallbladder Sarcoma:

19
Gallbladder
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Publications for Gallbladder Sarcoma

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Articles related to Gallbladder Sarcoma:

# Title Authors PMID Year
1
Primary Leiomyosarcoma of the Gallbladder. 61
32670649 2020
2
Dedifferentiated liposarcoma of the gallbladder: first reported case. 61
30419915 2018
3
Primary leiomyosarcoma of gallbladder. 61
23230561 2012
4
Primary gallbladder sarcoma: a clinicopathologic study of 15 cases, heterogeneous sarcomas with poor outcome, except pediatric botryoid rhabdomyosarcoma. 61
19194282 2009
5
Gallbladder sarcoma: a clinicopathological study of seven cases from the UK and Austria with emphasis on morphological subtypes. 61
18618258 2009
6
[Case of primary gallbladder sarcoma]. 61
5549090 1971
7
[Two cases of gallbladder sarcoma]. 61
13243000 1955
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Variations for Gallbladder Sarcoma

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Expression for Gallbladder Sarcoma

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Search GEO for disease gene expression data for Gallbladder Sarcoma.
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Pathways for Gallbladder Sarcoma

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Pathways related to Gallbladder Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Cytoskeleton remodeling Neurofilaments 23
Show member pathways
 11.19 KRT18 DES
2
Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers 64
10.78 MYOG MYOD1 DES
3
Myogenesis 65
Show member pathways
 10.72 MYOG MYOD1
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GO Terms for Gallbladder Sarcoma

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Biological processes related to Gallbladder Sarcoma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 muscle organ development GO:0007517 9.52 MYOG MYOD1
2 cellular response to retinoic acid GO:0071300 9.51 MYOG BRINP1
3 skeletal muscle tissue development GO:0007519 9.49 MYOG MYOD1
4 skeletal muscle cell differentiation GO:0035914 9.48 MYOG MYOD1
5 cellular response to estradiol stimulus GO:0071392 9.46 MYOG MYOD1
6 positive regulation of muscle cell differentiation GO:0051149 9.43 MYOG MYOD1
7 skeletal muscle fiber development GO:0048741 9.4 MYOG MYOD1
8 skeletal muscle tissue regeneration GO:0043403 9.37 MYOG MYOD1
9 positive regulation of myoblast differentiation GO:0045663 9.32 MYOG MYOD1
10 myoblast differentiation GO:0045445 9.26 MYOG MYOD1
11 myotube differentiation GO:0014902 9.16 MYOG MYOD1
12 positive regulation of skeletal muscle fiber development GO:0048743 8.96 MYOG MYOD1
13 muscle cell fate commitment GO:0042693 8.62 MYOG MYOD1

Molecular functions related to Gallbladder Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 proximal promoter sequence-specific DNA binding GO:0000987 9.16 MYOG MYOD1
2 chromatin DNA binding GO:0031490 8.96 MYOG MYOD1
3 E-box binding GO:0070888 8.62 MYOG MYOD1
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Sources for Gallbladder Sarcoma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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