MCID: GLL009
MIFTS: 22

Gallbladder Signet Ring Cell Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gallbladder Signet Ring Cell Adenocarcinoma

MalaCards integrated aliases for Gallbladder Signet Ring Cell Adenocarcinoma:

Name: Gallbladder Signet Ring Cell Adenocarcinoma 12 15
Signet Ring Cell Carcinoma of the Gallbladder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3499
NCIt 50 C5745
UMLS 70 C1333758

Summaries for Gallbladder Signet Ring Cell Adenocarcinoma

MalaCards based summary : Gallbladder Signet Ring Cell Adenocarcinoma, also known as signet ring cell carcinoma of the gallbladder, is related to signet ring cell adenocarcinoma and linitis plastica. An important gene associated with Gallbladder Signet Ring Cell Adenocarcinoma is KRT7 (Keratin 7), and among its related pathways/superpathways are Cytoskeletal Signaling and VEGF Signaling. Affiliated tissues include lymph node and skin, and related phenotype is S arrest.

Related Diseases for Gallbladder Signet Ring Cell Adenocarcinoma

Diseases related to Gallbladder Signet Ring Cell Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 180)
# Related Disease Score Top Affiliating Genes
1 signet ring cell adenocarcinoma 30.7 MUC1 KRT7 CDH1
2 linitis plastica 30.5 KRT7 CDH1
3 cholecystitis 30.1 MUC1 CDH1
4 mucinous adenocarcinoma 30.1 MUC1 KRT7
5 gallbladder cancer 10.5
6 cholelithiasis 10.4
7 obstructive jaundice 10.2
8 gallbladder adenocarcinoma 10.2
9 appendix adenocarcinoma 10.2
10 rare tumor 10.2
11 thrombotic microangiopathy 10.2
12 renal pelvis adenocarcinoma 10.1 KRT7 CDH1
13 gastric diffuse adenocarcinoma 10.1 KRT7 CDH1
14 cystitis 10.1 KRT7 CDH1
15 esophageal adenosquamous carcinoma 10.1 KRT7 CDH1
16 adenoid squamous cell carcinoma 10.1 KRT7 CDH1
17 breast neuroendocrine neoplasm 10.1 KRT7 CDH1
18 keratinizing squamous cell carcinoma 10.1 KRT7 CDH1
19 corneal dystrophy, posterior polymorphous, 4 10.1 KRT7 CDH1
20 borst-jadassohn intraepidermal carcinoma 10.1 KRT7 CDH1
21 pulmonary sclerosing hemangioma 10.1 KRT7 CDH1
22 mixed cell type cancer 10.0 KRT7 CDH1
23 tonsil cancer 10.0 KRT7 CDH1
24 teratoma 10.0 KRT7 CDH1
25 bronchiolo-alveolar adenocarcinoma 10.0 KRT7 CDH1
26 oropharynx cancer 10.0 KRT7 CDH1
27 lung giant cell carcinoma 10.0 MYC CDH1
28 esophagus adenocarcinoma 10.0 MYC CDH1
29 rectum adenocarcinoma 10.0 MYC KRT7
30 cervical adenocarcinoma 10.0 MYC KRT7
31 colonic benign neoplasm 10.0 MYC CDH1
32 keratoacanthoma 10.0 MYC CDH1
33 breast carcinoma in situ 9.9 MYC CDH1
34 scrotum paget's disease 9.9 MUC1 KRT7
35 intestinal benign neoplasm 9.9 MYC CDH1
36 pancreatic foamy gland adenocarcinoma 9.9 MUC1 KRT7
37 urinary bladder villous adenoma 9.9 MUC1 KRT7
38 villous adenoma 9.9 MUC1 KRT7
39 mucinous intrahepatic cholangiocarcinoma 9.9 MUC1 KRT7
40 middle ear adenoma 9.9 MUC1 KRT7
41 bile duct cystadenocarcinoma 9.9 MUC1 KRT7
42 cystadenocarcinoma 9.9 MUC1 KRT7
43 colonic lymphangioma 9.9 MUC1 KRT7
44 biliary papillomatosis 9.9 MUC1 KRT7
45 bile duct mucoepidermoid carcinoma 9.9 MUC1 KRT7
46 lipoadenoma 9.9 MUC1 KRT7
47 parachordoma 9.9 MUC1 KRT7
48 glandular cystitis 9.9 MUC1 KRT7
49 pancreatic mucinous cystadenoma 9.9 MUC1 KRT7
50 cystadenoma 9.9 MUC1 KRT7

Graphical network of the top 20 diseases related to Gallbladder Signet Ring Cell Adenocarcinoma:



Diseases related to Gallbladder Signet Ring Cell Adenocarcinoma

Symptoms & Phenotypes for Gallbladder Signet Ring Cell Adenocarcinoma

GenomeRNAi Phenotypes related to Gallbladder Signet Ring Cell Adenocarcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 S arrest GR00098-A-2 8.32 KRT7

Drugs & Therapeutics for Gallbladder Signet Ring Cell Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Gallbladder Signet Ring Cell Adenocarcinoma

Genetic Tests for Gallbladder Signet Ring Cell Adenocarcinoma

Anatomical Context for Gallbladder Signet Ring Cell Adenocarcinoma

MalaCards organs/tissues related to Gallbladder Signet Ring Cell Adenocarcinoma:

40
Lymph Node, Skin

Publications for Gallbladder Signet Ring Cell Adenocarcinoma

Articles related to Gallbladder Signet Ring Cell Adenocarcinoma:

(show all 14)
# Title Authors PMID Year
1
A Case of Signet Ring Cell Carcinoma of the Gallbladder Which Was Treated by Aggressive Surgery and Intensive Adjuvant Chemotherapy. 61
26825388 2017
2
Linitis plastica like primary signet ring cell carcinoma of the gallbladder - an extremely rare variant. 61
28195258 2016
3
Incidental signet ring cell carcinoma of the gallbladder in routine histopathology. 61
28149128 2016
4
Signet-ring cell carcinoma of the gallbladder complicated by pulmonary tumor thrombotic microangiopathy. 61
24881735 2014
5
Signet-Ring Cell Carcinoma of the Gallbladder after Gastric Bypass. 61
21727994 2012
6
[Signet ring cell carcinoma of the gallbladder]. 61
22469166 2012
7
Signet ring cell carcinoma of the gallbladder: a case report. 61
23016488 2011
8
Metastatic gallbladder adenocarcinoma with signet-ring cells: A case report. 61
21917161 2011
9
Signet ring cell carcinoma of the gallbladder in a 22-year-old man: a case report and review of the literature. 61
21068067 2010
10
Signet ring cell carcinoma of gallbladder with celiac lymph node metastasis in a young man. 61
21119284 2010
11
A case of signet-ring cell carcinoma of the gallbladder: immunohistochemistry and differential diagnosis. 61
21086733 2010
12
Signet-ring cell carcinoma of the gallbladder: a case report. 61
18461291 2008
13
Signet-ring cell carcinoma of the gallbladder with skin metastases. 61
17680973 2007
14
[A case of signet ring cell carcinoma of the gallbladder with anomalous pancreaticobiliary ductal union]. 61
10707592 2000

Variations for Gallbladder Signet Ring Cell Adenocarcinoma

Expression for Gallbladder Signet Ring Cell Adenocarcinoma

Search GEO for disease gene expression data for Gallbladder Signet Ring Cell Adenocarcinoma.

Pathways for Gallbladder Signet Ring Cell Adenocarcinoma

Pathways related to Gallbladder Signet Ring Cell Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.82 MUC1 KRT7 CDH1
2
Show member pathways
11.6 MYC MUC1 CDH1
3 11.52 MUC1 CDH1
4 11.46 MYC MUC1
5 11.38 MYC CDH1
6 11.22 MYC CDH1
7
Show member pathways
11.17 MYC MUC1 CDH1
8 11.12 MYC CDH1

GO Terms for Gallbladder Signet Ring Cell Adenocarcinoma

Sources for Gallbladder Signet Ring Cell Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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