MCID: GNG005
MIFTS: 55

Gangliocytoma

Categories: Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Gangliocytoma

MalaCards integrated aliases for Gangliocytoma:

Name: Gangliocytoma 12 52 58 15
Ganglioneuroma 43 71

Classifications:

Orphanet: 58  
Rare neurological diseases


Summaries for Gangliocytoma

NIH Rare Diseases : 52 Gangliocytoma is a rare type of central nervous system (CNS) tumor made up of mature neurons . Gangliocytomas may occur in all age groups but most often occur in people between the ages of 10 and 30. The most common site is the temporal lobe of the brain, but they can arise anywhere in the CNS including the cerebellum, brainstem, floor of the third ventricle, and spinal cord. They are among the most frequent tumors associated with epilepsy . Signs and symptoms may depend on the tumor's location and may include seizures (most commonly); increased brain pressure; endocrine disorders ; and focal symptoms . Gangliocytomas are generally slow-growing and usually do not become malignant. Treatment involves surgical removal of the tumor. Click here to view a separate page about dysplastic gangliocytoma of the cerebellum (also called Lhermitte-Duclose disease) .

MalaCards based summary : Gangliocytoma, also known as ganglioneuroma, is related to cutaneous ganglioneuroma and ganglioneuroblastoma, and has symptoms including seizures An important gene associated with Gangliocytoma is PVALB (Parvalbumin), and among its related pathways/superpathways are Neuroscience and Circadian rythm related genes. The drugs Trametinib and Dabrafenib have been mentioned in the context of this disorder. Affiliated tissues include pituitary, cerebellum and brain, and related phenotypes are ganglioneuroma and hemianopia

Disease Ontology : 12 A central nervous system benign neoplasm that has material basis in mature neurons, and is classified by the absence of neoplastic glial cells.

Wikipedia : 74 Ganglioglioma is a rare, slow-growing primary central nervous system (CNS) tumor which most frequently... more...

Related Diseases for Gangliocytoma

Diseases related to Gangliocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 535)
# Related Disease Score Top Affiliating Genes
1 cutaneous ganglioneuroma 34.1 SYP CHGA
2 ganglioneuroblastoma 30.7 TH SYP CRH
3 nodular ganglioneuroblastoma 30.3 SYP CHGA
4 chromophobe adenoma 30.2 PRL POMC
5 hyperprolactinemia 30.2 PRL POMC GHRH
6 pituitary adenoma, prolactin-secreting 30.2 PRL POMC CHGA
7 desmoplastic infantile ganglioglioma 30.2 SYP GFAP
8 growth hormone secreting pituitary adenoma 30.1 PRL POMC GHRH
9 paraganglioma 30.1 TH SYP GFAP CHGA
10 pineal gland cancer 30.1 SYP GFAP
11 thyroid gland medullary carcinoma 30.0 SYP POMC CHGA
12 adrenal cortical adenoma 30.0 SYP POMC CHGA
13 acromegaly 30.0 PRL POMC GHRH CRH
14 extra-adrenal pheochromocytoma 30.0 SYP CHGA
15 mediastinal cancer 29.9 SYP CHGA
16 parachordoma 29.9 GFAP CHGA
17 cystic teratoma 29.8 SYP PTEN GFAP
18 adrenal cortical carcinoma 29.8 SYP POMC CHGA
19 malignant pheochromocytoma 29.8 TH SYP CHGA
20 obstructive hydrocephalus 29.8 SYP PRL GFAP
21 acth-secreting pituitary adenoma 29.7 PRL POMC CRH
22 neuroendocrine tumor 29.7 SYP POMC GHRH CHGA
23 pineocytoma 29.6 SYP GFAP CHGA
24 central neurocytoma 29.6 SYP GFAP CHGA
25 dementia 29.6 TH SYP LOC109504728 GFAP C9orf72
26 pituitary adenoma 29.5 PRL POMC GHRH CRH CHGA
27 hemangioma 29.5 SYP PTEN CHGA
28 teratoma 29.5 SYP PTEN GFAP CHGA
29 focal epilepsy 29.4 RBFOX3 PVALB PRL GFAP
30 frontotemporal dementia 29.4 LOC109504728 GFAP CHGA C9orf72
31 amenorrhea 29.3 PRL POMC CRH
32 primary hyperparathyroidism 29.3 PRL POMC GHRH CHGA
33 ganglioglioma 29.3 TH SYP PVALB KIAA1549 GFAP CHGA
34 pheochromocytoma 29.2 TH SYP PRL POMC CRH CHGA
35 aceruloplasminemia 29.2 TH SYP RBFOX3 GFAP C9orf72
36 neuroblastoma 29.2 TH SYP PTEN GFAP CHGA
37 adrenal carcinoma 29.1 SYP POMC CRH CHGA
38 ganglioneuroma 29.0 TH SYP PTEN GFAP CHGA
39 functioning pituitary adenoma 29.0 PRL POMC GHRH CRH
40 hydrocephalus 28.9 SYP PTEN PRL GFAP CRH C9orf72
41 amyotrophic lateral sclerosis 1 28.9 TH SYP RBFOX3 PVALB GFAP C9orf72
42 meningioma, familial 28.7 SYP PTEN PRL POMC KIAA1549 GFAP
43 tuberous sclerosis 28.5 SYP PVALB PTEN POMC GFAP CHGA
44 conn's syndrome 28.1 PRL POMC GHRH CRH CHGA
45 central hypoventilation syndrome, congenital 11.8
46 cowden syndrome 11.7
47 cowden syndrome 1 11.7
48 multiple endocrine neoplasia, type iib 11.7
49 multiple endocrine neoplasia, type iia 11.5
50 neuroblastoma 1 11.2

Graphical network of the top 20 diseases related to Gangliocytoma:



Diseases related to Gangliocytoma

Symptoms & Phenotypes for Gangliocytoma

Human phenotypes related to Gangliocytoma:

58 31 (show all 26)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 ganglioneuroma 58 31 hallmark (90%) Very frequent (99-80%) HP:0003005
2 hemianopia 58 31 frequent (33%) Frequent (79-30%) HP:0012377
3 headache 58 31 frequent (33%) Frequent (79-30%) HP:0002315
4 spinal cord tumor 58 31 frequent (33%) Frequent (79-30%) HP:0010302
5 scoliosis 58 31 occasional (7.5%) Occasional (29-5%) HP:0002650
6 hyperhidrosis 58 31 occasional (7.5%) Occasional (29-5%) HP:0000975
7 paresthesia 58 31 occasional (7.5%) Occasional (29-5%) HP:0003401
8 abnormality of brainstem morphology 58 31 occasional (7.5%) Occasional (29-5%) HP:0002363
9 focal-onset seizure 58 31 occasional (7.5%) Occasional (29-5%) HP:0007359
10 growth hormone excess 58 31 occasional (7.5%) Occasional (29-5%) HP:0000845
11 pituitary null cell adenoma 58 31 occasional (7.5%) Occasional (29-5%) HP:0011761
12 accelerated skeletal maturation 58 31 occasional (7.5%) Occasional (29-5%) HP:0005616
13 impotence 58 31 occasional (7.5%) Occasional (29-5%) HP:0000802
14 adrenocorticotropic hormone excess 58 31 occasional (7.5%) Occasional (29-5%) HP:0011749
15 distal muscle weakness 58 31 occasional (7.5%) Occasional (29-5%) HP:0002460
16 amenorrhea 58 31 occasional (7.5%) Occasional (29-5%) HP:0000141
17 decreased female libido 58 31 occasional (7.5%) Occasional (29-5%) HP:0030018
18 abnormal prolactin level 58 31 occasional (7.5%) Occasional (29-5%) HP:0040086
19 dementia 58 31 very rare (1%) Very rare (<4-1%) HP:0000726
20 pituitary prolactin cell adenoma 58 31 very rare (1%) Very rare (<4-1%) HP:0006767
21 polyphagia 58 31 very rare (1%) Very rare (<4-1%) HP:0002591
22 abnormal cerebellum morphology 58 31 very rare (1%) Very rare (<4-1%) HP:0001317
23 excessive daytime somnolence 58 31 very rare (1%) Very rare (<4-1%) HP:0001262
24 syringomyelia 58 31 very rare (1%) Very rare (<4-1%) HP:0003396
25 neoplasm of the central nervous system 58 Frequent (79-30%)
26 abnormality of the pituitary gland 58 Occasional (29-5%)

UMLS symptoms related to Gangliocytoma:


seizures

MGI Mouse Phenotypes related to Gangliocytoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.06 C9orf72 CRH GFAP GHRH KIAA1549 POMC
2 homeostasis/metabolism MP:0005376 9.96 C9orf72 CHGA CRH GFAP GHRH KIAA1549
3 liver/biliary system MP:0005370 9.7 C9orf72 CRH GHRH POMC PRL PTEN
4 nervous system MP:0003631 9.7 C9orf72 CHGA CRH GFAP GHRH POMC
5 no phenotypic analysis MP:0003012 9.1 C9orf72 CHGA CRH POMC PVALB TH

Drugs & Therapeutics for Gangliocytoma

Drugs for Gangliocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Trametinib Approved Phase 4 871700-17-3 11707110
2
Dabrafenib Approved, Investigational Phase 4 1195765-45-7 44462760 44516822
3 Protein Kinase Inhibitors Phase 4
4
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
5
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
6 Antimitotic Agents Phase 2
7
Irinotecan Approved, Investigational Phase 1 97682-44-5, 100286-90-6 60838
8
Bevacizumab Approved, Investigational Phase 1 216974-75-3
9 topoisomerase I inhibitors Phase 1
10 Antineoplastic Agents, Immunological Phase 1
11 Angiogenesis Inhibitors Phase 1
12 Topoisomerase Inhibitors Phase 1
13
Cyclophosphamide Approved, Investigational 50-18-0, 6055-19-2 2907
14
Cisplatin Approved 15663-27-1 84093 441203 2767
15
Etoposide Approved 33419-42-0 36462
16
Octreotide Approved, Investigational 83150-76-9 383414 6400441
17 Immunologic Factors
18 Alkylating Agents
19 Immunosuppressive Agents
20 Antirheumatic Agents
21 Etoposide phosphate
22 Gastrointestinal Agents
23 Fluorodeoxyglucose F18
24 Radiopharmaceuticals
25 Antineoplastic Agents, Hormonal
26 Edotreotide

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 An Open Label, Multi-center Roll-over Study to Assess Long-term Effect in Pediatric Patients Treated With Tafinlar (Dabrafenib) and/or Mekinist (Trametinib) Not yet recruiting NCT03975829 Phase 4 dabrafenib;trametinib
2 Phase II Open-label Global Study to Evaluate the Effect of Dabrafenib in Combination With Trametinib in Children and Adolescent Patients With BRAF V600 Mutation Positive Low Grade Glioma (LGG) or Relapsed or Refractory High Grade Glioma (HGG) Recruiting NCT02684058 Phase 2 dabrafenib;trametinib;Carboplatin with vincristine
3 Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS Tumors, A Feasibility Study Completed NCT01999270 Phase 1 Irinotecan;Bevacizumab
4 Protocol for Infants With Neuroblastoma Diagnosed Under the Age of One Year Unknown status NCT00287950 carboplatin;cisplatin;cyclophosphamide;etoposide;vincristine sulfate
5 Evaluation of the Safety and Sensitivity of 68Ga-DOTATOC PET/CT for Imaging NET Patients Recruiting NCT03583528
6 International Congenital Central Hypoventilation Syndrome (CCHS) REDCap Registry Recruiting NCT03088020
7 Utility of Gallium-68-DOTA-Octreotate PET/CT in the Characterization of Pediatric Neuroendocrine Tumors Not yet recruiting NCT04040088 Early Phase 1 Gallium Ga 68-DOTATATE
8 Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) Children s Oncology Group Terminated NCT01117168

Search NIH Clinical Center for Gangliocytoma

Cochrane evidence based reviews: ganglioneuroma

Genetic Tests for Gangliocytoma

Anatomical Context for Gangliocytoma

MalaCards organs/tissues related to Gangliocytoma:

40
Pituitary, Cerebellum, Brain, Spinal Cord, Adrenal Gland, Temporal Lobe, Colon

Publications for Gangliocytoma

Articles related to Gangliocytoma:

(show top 50) (show all 1838)
# Title Authors PMID Year
1
Colonic Neurogenic Lesion: An Admixture of Mucosal Neurofibromatous Lesion and Submucosal Ganglioneuromatous Lesion With Transition. 61
32028811 2020
2
Rare occurrence of gangliocytoma in the medulla oblongata. 61
31650219 2020
3
The ganglioside GD2 as a circulating tumor biomarker for neuroblastoma. 61
31612589 2020
4
An interesting cause of chronic abdominal pain in a child. 61
31530107 2020
5
Paravertebral lipomatous ganglioneuroma with intraspinal extension. Case report and literature review. 61
31129025 2020
6
Adrenal masses in children: Imaging, surgical treatment and outcome. 61
30962018 2020
7
Pathological Thoracic Spine Scoliosis Due to Ganglioneuroma. 61
31033504 2020
8
Postoperative Horner's syndrome following excision of incidental cervical ganglioneuroma during hemithyroidectomy and parathyroid gland exploration. 61
31969402 2020
9
Transcervical excision combined with uniportal VATS for apical ganglioneuroma: a case report. 61
31929973 2019
10
Concurrent Adrenal and Extra-Adrenal Ganglioneuromas: A Case Report. 61
31806861 2019
11
A radiological and histological comparison of two unusual adrenal incidentalomas. 61
31901917 2019
12
Importance of Magnetic Resonance Imaging With Diffusion-weighted Imaging in Guiding Biopsy of Nodular Ganglioneuroblastoma: A Case Report. 61
31815883 2019
13
Resection of a Symptomatic Dysplastic Cerebellar Gangliocytoma: 2-Dimensional Operative Video. 61
31807781 2019
14
Occurrence of paratesticular ganglioneuroma 18 years after concurrent adrenal ganglioneuroma and papillary thyroid carcinoma - a case report. 61
31888521 2019
15
[A Case of Neurofibromatosis Type 1 Presenting Voiding Symptoms Caused by Giant Bladder Diverticulum]. 61
31933336 2019
16
Rare Images of a Peripancreatic Ganglioneuroma. 61
31839657 2019
17
Cytopathological spectrum of peripheral neuroblastic tumours in fine needle aspiration cytology and categorisation as per International Neuroblastoma Pathology Classification. 61
31231909 2019
18
Ganglioneuroma of the Phrenic Nerve: An Unusual Site. 61
31784346 2019
19
Giant spinal nerve sheath tumours - Surgical challenges: case series and literature review. 61
30836023 2019
20
Congenital malformation syndromes associated with peripheral neuroblastic tumors: A systematic review. 61
31264798 2019
21
Rare adrenal ganglioneuroma encasing the inferior vena cava. 61
30117649 2019
22
[A Case of Adrenal Ganglioneuroma that was Hard to Diagnose]. 61
31697885 2019
23
Mixed gangliocytoma-pituitary adenoma containing GH and GHRH co-secreting adenoma cells. 61
31581122 2019
24
Involvement of A3 Adenosine Receptor in Neuroblastoma Progression via Modulation of the Hypoxic/Angiogenic Pathway. 61
31166001 2019
25
Cause of postprandial vomiting - a giant retroperitoneal ganglioneuroma enclosing large blood vessels: A case report. 61
31559301 2019
26
FUBP1 promotes neuroblastoma proliferation via enhancing glycolysis-a new possible marker of malignancy for neuroblastoma. 61
31511046 2019
27
Glioneuronal Tumor With Features of Ganglioglioma and Neurocytoma Arising in the Fourth Ventricle: A Report of 2 Unusual Cases and a Review of Infratentorial Gangliogliomas. 61
31361005 2019
28
Magnetic resonance imaging of adrenal gland: state of the art. 61
31559189 2019
29
Comprehensive Evaluation of Rare Pituitary Lesions: A Single Tertiary Care Pituitary Center Experience and Review of the Literature. 61
31209729 2019
30
Lumbar Ganglioneuroma from the Paravertebral Body Presenting in Continuity Between Intradural and Extradural Spaces. 61
31102769 2019
31
Exome sequencing identifies predisposing and fusion gene in ganglioneuroma, ganglioneuroblastoma and neuroblastoma. 61
31698611 2019
32
Multidisciplinary surgical strategy for dumbbell neuroblastoma: A single-center experience of 32 cases. 61
30828979 2019
33
Footpad peripheral ganglioneuroblastoma in a dog. 61
30950551 2019
34
β2‑adrenergic receptor signaling promotes neuroblastoma cell proliferation by activating autophagy. 61
31524241 2019
35
Frequency of ALK and GD2 Expression in Neuroblastoma. 61
30955398 2019
36
A Unique Combined Ganglioneuroma Schwannoma Tumor Mimicking Adrenal Malignancy. 61
31667035 2019
37
Retroperitoneoscopic resection of a T11-L2 right-sided ganglioneuroma. 61
30879753 2019
38
Subacute Arsenic Neuropathy: Clinical and Electrophysiological Observations. 61
31602157 2019
39
Laparoscopic adrenalectomy for ganglioneuroma presenting as an adrenal incidentaloma. 61
30618428 2019
40
Presacral masses and sacrococcygeal teratomas in patients with and without anorectal malformations: A single institution comparative study. 61
30630596 2019
41
Isolated Intestinal Ganglioneuroma Mimicking Small Bowel Crohn's Disease. 61
31620517 2019
42
Bilateral Recurrent Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) in Cowden Syndrome: A Case Report and Literature Review. 61
30905649 2019
43
AN INCIDENTAL COLLISION TUMOR OF THE SELLA TURCICA. 61
31967045 2019
44
Imaging Analysis of Ganglioneuroma and Quantitative Analysis of Paraspinal Ganglioneuroma. 61
31306406 2019
45
Targeting β3-adrenergic receptor signaling inhibits neuroblastoma cell growth via suppressing the mTOR pathway. 61
31030945 2019
46
[Ganglioneuroma in poststyloid space removed under endoscope through transoral approach: a case report]. 61
31163562 2019
47
Approach to a Posterior Cervicomediastinal Ganglioneuroma. 61
30365962 2019
48
Very Unusual Sellar/Suprasellar Region Masses: A Review. 61
31233145 2019
49
Early Basal Cortisol Level as a Predictor of Hypothalamic-Pituitary-Adrenal (HPA) Axis Function After Pituitary Tumor Surgery. 61
31091548 2019
50
Cervical ganglioneuroma: A case report and review of the literature. 61
30985715 2019

Variations for Gangliocytoma

Cosmic variations for Gangliocytoma:

9 (show all 46)
# Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA GRCh38 Location Conf
1 COSM149315872 ZFHX3 central nervous system,brain,other,ganglioglioma c.10376C>T p.P3459L 16:72787900-72787900 9
2 COSM89046819 NF2 central nervous system,brain,other,neoplasm c.575A>G p.Y192C 22:29655652-29655652 9
3 COSM89230121 IDH2 central nervous system,temporal lobe,other,ganglioglioma c.492G>A p.W164* 15:90088629-90088629 9
4 COSM103033757 IDH1 central nervous system,brain,other,neoplasm c.395G>A p.R132H 2:208248388-208248388 9
5 COSM103033796 IDH1 central nervous system,brain,other,neoplasm c.394C>T p.R132C 2:208248389-208248389 9
6 COSM103034325 IDH1 central nervous system,brain,other,neoplasm c.394C>A p.R132S 2:208248389-208248389 9
7 COSM103034038 IDH1 central nervous system,brain,other,neoplasm c.394C>G p.R132G 2:208248389-208248389 9
8 COSM103034000 IDH1 central nervous system,brain,other,neoplasm c.395G>T p.R132L 2:208248388-208248388 9
9 COSM95516467 H3-3A central nervous system,spinal cord,other,ganglioglioma c.83A>T p.K28M 1:226064434-226064434 9
10 COSM102860866 FOXO3 central nervous system,brain,other,neoplasm c.583A>T p.K195* 6:108561791-108561791 9
11 COSM99025171 BRCA2 central nervous system,brain,other,ganglioglioma c.9085G>A p.A3029T 13:32379881-32379881 9
12 COSM150563774 BRAF central nervous system,brain,other,ganglioglioma c.1799T>A p.V600E 7:140753336-140753336 9
13 COSM88154796 ATM central nervous system,brain,other,ganglioglioma c.6315G>C p.R2105S 11:108317489-108317489 9
14 COSM149385292 central nervous system,brain,other,ganglioglioma c.1919T>A p.V640E 7:140753336-140753336 9
15 COSM90465359 central nervous system,brain,other,neoplasm c.395G>A p.R132H 2:208248388-208248388 9
16 COSM112752230 central nervous system,brain,other,neoplasm c.395G>A p.R132H 2:208248388-208248388 9
17 COSM95520463 central nervous system,spinal cord,other,ganglioglioma c.83A>T p.K28M 1:226064434-226064434 9
18 COSM88803061 central nervous system,brain,other,ganglioglioma c.1919T>A p.V640E 7:140753336-140753336 9
19 COSM102656129 central nervous system,brain,other,neoplasm c.575A>G p.Y192C 22:29655652-29655652 9
20 COSM118787231 central nervous system,brain,other,ganglioglioma c.1799T>A p.V600E 7:140753336-140753336 9
21 COSM114609379 central nervous system,brain,other,ganglioglioma c.6315G>C p.R2105S 11:108317489-108317489 9
22 COSM93220513 central nervous system,brain,other,neoplasm c.583A>T p.K195* 6:108561791-108561791 9
23 COSM112752272 central nervous system,brain,other,neoplasm c.394C>T p.R132C 2:208248389-208248389 9
24 COSM90465396 central nervous system,brain,other,neoplasm c.394C>T p.R132C 2:208248389-208248389 9
25 COSM105514140 central nervous system,brain,other,neoplasm c.575A>G p.Y192C 22:29655652-29655652 9
26 COSM95523395 central nervous system,spinal cord,other,ganglioglioma c.83A>T p.K28M 1:226064434-226064434 9
27 COSM94463526 central nervous system,brain,other,neoplasm c.452A>G p.Y151C 22:29655652-29655652 9
28 COSM90466087 central nervous system,brain,other,neoplasm c.394C>A p.R132S 2:208248389-208248389 9
29 COSM102040939 central nervous system,brain,other,ganglioglioma c.7634C>T p.P2545L 16:72787900-72787900 9
30 COSM90465733 central nervous system,brain,other,neoplasm c.394C>G p.R132G 2:208248389-208248389 9
31 COSM95526696 central nervous system,spinal cord,other,ganglioglioma c.83A>T p.K28M 1:226064434-226064434 9
32 COSM112752610 central nervous system,brain,other,neoplasm c.394C>G p.R132G 2:208248389-208248389 9
33 COSM112752921 central nervous system,brain,other,neoplasm c.394C>A p.R132S 2:208248389-208248389 9
34 COSM112752563 central nervous system,brain,other,neoplasm c.395G>T p.R132L 2:208248388-208248388 9
35 COSM102848205 central nervous system,brain,other,neoplasm c.575A>G p.Y192C 22:29655652-29655652 9
36 COSM93474794 central nervous system,brain,other,neoplasm c.575A>G p.Y192C 22:29655652-29655652 9
37 COSM87290663 central nervous system,brain,other,ganglioglioma c.10376C>T p.P3459L 16:72787900-72787900 9
38 COSM131103045 central nervous system,brain,other,ganglioglioma c.9085G>A p.A3029T 13:32379881-32379881 9
39 COSM89067962 central nervous system,brain,other,neoplasm c.326A>G p.Y109C 22:29655652-29655652 9
40 COSM105111282 central nervous system,brain,other,neoplasm c.447+13367A>G p.? 22:29655652-29655652 9
41 COSM133282459 central nervous system,temporal lobe,other,ganglioglioma c.336G>A p.W112* 15:90088629-90088629 9
42 COSM136793306 central nervous system,temporal lobe,other,ganglioglioma c.208-127G>A p.? 15:90088629-90088629 9
43 COSM130561817 central nervous system,brain,other,ganglioglioma c.641-8418C>G p.? 11:108317489-108317489 9
44 COSM95502154 central nervous system,brain,other,neoplasm c.449A>G p.Y150C 22:29655652-29655652 9
45 COSM90465675 central nervous system,brain,other,neoplasm c.395G>T p.R132L 2:208248388-208248388 9
46 COSM92446479 central nervous system,brain,other,neoplasm c.326A>G p.Y109C 22:29655652-29655652 9

Expression for Gangliocytoma

Search GEO for disease gene expression data for Gangliocytoma.

Pathways for Gangliocytoma

GO Terms for Gangliocytoma

Cellular components related to Gangliocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuronal cell body GO:0043025 9.56 TH RBFOX3 PVALB CRH
2 neuron projection GO:0043005 9.35 TH SYP PTEN GHRH C9orf72
3 terminal bouton GO:0043195 9.33 TH SYP GHRH
4 perikaryon GO:0043204 9.02 TH RBFOX3 GHRH CRH C9orf72

Biological processes related to Gangliocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to immobilization stress GO:0035902 9.37 TH CRH
2 response to ethanol GO:0045471 9.33 TH PTEN CRH
3 response to corticosterone GO:0051412 9.32 TH CRH
4 synaptic transmission, dopaminergic GO:0001963 9.26 TH CRH
5 long-term synaptic potentiation GO:0060291 9.13 PTEN GFAP CRH
6 response to ether GO:0045472 8.62 TH CRH

Molecular functions related to Gangliocytoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.8 PRL POMC CRH

Sources for Gangliocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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