GAPPS
MCID: GST086
MIFTS: 15

Gastric Adenocarcinoma and Proximal Polyposis of the Stomach (GAPPS)

Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Genetic diseases, Rare diseases

Aliases & Classifications for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

MalaCards integrated aliases for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach:

Name: Gastric Adenocarcinoma and Proximal Polyposis of the Stomach 59
Familial Fundic Gland Polyposis with Gastric Cancer 59
Gapps 59

Characteristics:

Orphanet epidemiological data:

59
gastric adenocarcinoma and proximal polyposis of the stomach
Inheritance: Autosomal dominant; Prevalence: <1/1000000 (Worldwide); Age of onset: Adult; Age of death: adult;

Classifications:



External Ids:

Orphanet 59 ORPHA314022

Summaries for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

MalaCards based summary : Gastric Adenocarcinoma and Proximal Polyposis of the Stomach, also known as familial fundic gland polyposis with gastric cancer, is related to adenocarcinoma and gastric adenocarcinoma. An important gene associated with Gastric Adenocarcinoma and Proximal Polyposis of the Stomach is APC (APC, WNT Signaling Pathway Regulator). Affiliated tissues include colon.

Related Diseases for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Diseases related to Gastric Adenocarcinoma and Proximal Polyposis of the Stomach via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 10.6
2 gastric adenocarcinoma 10.6
3 polyposis of gastric fundus without polyposis coli 10.2
4 polyposis, gastric 10.2
5 gastric cancer 10.2
6 familial adenomatous polyposis 10.2

Graphical network of the top 20 diseases related to Gastric Adenocarcinoma and Proximal Polyposis of the Stomach:



Diseases related to Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Symptoms & Phenotypes for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Drugs & Therapeutics for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Clinical and Laboratory Analysis of Familial Cancer Recruiting NCT02565004

Search NIH Clinical Center for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Genetic Tests for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Anatomical Context for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

MalaCards organs/tissues related to Gastric Adenocarcinoma and Proximal Polyposis of the Stomach:

41
Colon

Publications for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Articles related to Gastric Adenocarcinoma and Proximal Polyposis of the Stomach:

# Title Authors Year
1
First report of an Asian family with gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) revealed with the germline mutation of the APC exon 1B promoter region. ( 29968043 )
2018
2
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) - a rare recently described gastric polyposis syndrome - report of a case. ( 29141268 )
2017
3
Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. ( 27087319 )
2016
4
The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review ofA the literature. ( 27343414 )
2016
5
β-Catenin activation in fundic gland polyps, gastric cancer and colonic polyps in families afflicted by 'gastric adenocarcinoma and proximal polyposis of the stomach' (GAPPS). ( 27406052 )
2016
6
Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS): a new autosomal dominant syndrome. ( 21813476 )
2012

Variations for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Expression for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Search GEO for disease gene expression data for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach.

Pathways for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

GO Terms for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

Sources for Gastric Adenocarcinoma and Proximal Polyposis of the Stomach

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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