GAVE
MCID: GST020
MIFTS: 39

Gastric Antral Vascular Ectasia (GAVE)

Categories: Blood diseases, Cardiovascular diseases, Gastrointestinal diseases, Rare diseases
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Aliases & Classifications for Gastric Antral Vascular Ectasia

MalaCards integrated aliases for Gastric Antral Vascular Ectasia:

Name: Gastric Antral Vascular Ectasia 11 19 43 14 16 75
Watermelon Stomach 11 19 75
Gave 19

Classifications:



External Ids:

Disease Ontology 11 DOID:2493
MeSH 43 D020252
NCIt 49 C84724
SNOMED-CT 68 412795008
UMLS 71 C0267211

Summaries for Gastric Antral Vascular Ectasia

GARD: 19 Watermelon stomach is a condition in which the lining of the stomach bleeds, causing it to look like the characteristic stripes of a watermelon when viewed by endoscopy. Signs and symptoms of Watermelon stomach include blood in the stool, hematemesis (vomiting blood) and anemia. The exact cause of Watermelon stomach is unknown; however, it is often diagnosed in people with other chronic (long-term) conditions such as cirrhosis (scarring of the liver and poor liver function), autoimmune disease, systemic sclerosis, and CREST syndrome.

MalaCards based summary: Gastric Antral Vascular Ectasia, also known as watermelon stomach, is related to active peptic ulcer disease and systemic scleroderma. An important gene associated with Gastric Antral Vascular Ectasia is MIR3677 (MicroRNA 3677). The drugs Acalabrutinib and Venetoclax have been mentioned in the context of this disorder. Affiliated tissues include liver, bone marrow and skeletal muscle.

Wikipedia: 75 Gastric antral vascular ectasia (GAVE) is an uncommon cause of chronic gastrointestinal bleeding or iron... more...

Related Diseases for Gastric Antral Vascular Ectasia

Diseases related to Gastric Antral Vascular Ectasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 400)
# Related Disease Score Top Affiliating Genes
1 active peptic ulcer disease 31.5 ATP4A ATP12A
2 systemic scleroderma 31.1 TOP1 GIT2 EXOSC10
3 esophageal varix 31.0 ATP4A ATP12A
4 angiodysplasia 31.0 ATP4A ATP12A
5 pernicious anemia 30.7 GAST ATP4A ATP12A
6 atrophic gastritis 30.7 GAST ATP4A ATP12A
7 diffuse scleroderma 30.4 TOP1 OXCT1 EXOSC10
8 autoimmune gastritis 30.4 GAST ATP4A ATP12A
9 crest syndrome 30.3 TOP1 EXOSC10
10 nutritional deficiency disease 30.2 GAST ATP4A ATP12A
11 limited scleroderma 30.2 TOP1 OXCT1 EXOSC10
12 gastroesophageal reflux 29.9 GAST ATP4A ATP12A
13 dyskinesia of esophagus 29.7 TOP1 EXOSC10 ATP4A ATP12A
14 deficiency anemia 11.1
15 transcobalamin ii deficiency 11.0
16 iron metabolism disease 11.0
17 iron deficiency anemia 11.0
18 liver cirrhosis 10.9
19 scleroderma, familial progressive 10.9
20 breast cancer 10.9
21 type 2 diabetes mellitus 10.9
22 hyperlipidemia, familial combined, 3 10.9
23 marfan syndrome 10.9
24 moebius syndrome 10.9
25 pseudo-von willebrand disease 10.9
26 spherocytosis, type 1 10.9
27 oeis complex 10.9
28 progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 1 10.9
29 smith-lemli-opitz syndrome 10.9
30 ichthyosis, x-linked 10.9
31 sacral defect with anterior meningocele 10.9
32 agammaglobulinemia 1, autosomal recessive 10.9
33 ehlers-danlos syndrome 10.9
34 stomach disease 10.9
35 portal hypertension 10.9
36 gastritis 10.7
37 chronic kidney disease 10.7
38 varicose veins 10.6
39 primary biliary cholangitis 10.6
40 connective tissue disease 10.6
41 autoimmune disease 10.5
42 sjogren syndrome 10.5
43 abdominal obesity-metabolic syndrome 1 10.5
44 leukemia, chronic myeloid 10.5
45 alcoholic liver cirrhosis 10.5
46 non-alcoholic steatohepatitis 10.4
47 telangiectasis 10.4
48 end stage renal disease 10.4
49 hypertension, essential 10.3
50 leukemia, acute myeloid 10.3

Graphical network of the top 20 diseases related to Gastric Antral Vascular Ectasia:



Diseases related to Gastric Antral Vascular Ectasia

Symptoms & Phenotypes for Gastric Antral Vascular Ectasia

Drugs & Therapeutics for Gastric Antral Vascular Ectasia

Drugs for Gastric Antral Vascular Ectasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acalabrutinib Approved, Investigational Phase 3 1420477-60-6 71226663 71226662
2
Venetoclax Approved, Investigational Phase 3 1257044-40-8 49846579
3
Obinutuzumab Approved, Investigational Phase 3 949142-50-1
4 Proton Pump Inhibitors Phase 2, Phase 3
5 Antineoplastic Agents, Immunological Phase 3
6
Ferrous succinate Approved Phase 2 10030-90-7
7
Iron Approved Phase 2 7439-89-6 29936
8
Thalidomide Approved, Investigational, Withdrawn Phase 2 50-35-1 5426
9 Anti-Bacterial Agents Phase 2
10 Anti-Infective Agents Phase 2
11 Angiogenesis Inhibitors Phase 2
12 Hematinics Phase 2
13 Immunosuppressive Agents Phase 2
14 Immunologic Factors Phase 2
15 Liver Extracts
16 Anesthetics

Interventional clinical trials:

(show all 11)
# Name Status NCT ID Phase Drugs
1 Prospective Randomized Study of Cryotherapy Versus Argon Plasma Coagulation Therapy for Treatment Of Watermelon Stomach Completed NCT00587405 Phase 2, Phase 3
2 Endoscopic Band Ligation vs Argon Plasma Coagulation for the Treatment of Gastric Antral Vascular Ectasia: a Randomized Clinical Trial Completed NCT01601639 Phase 3
3 A Prospective, Open-label, Multicentre, Randomized, Phase-3-trial of Acalabrutinib, Obinutuzumab and Venetoclax (GAVE) Compared to Obinutuzumab and Venetoclax (GVE) in Previously Untreated Patients With High Risk (17P-deletion, TP53-mutation or Complex Karyotype) Chronic Lymphatic Leukemia (CLL) Recruiting NCT05197192 Phase 3 Obinutuzumab;Venetoclax;Acalabrutinib
4 Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular Malformation : An Open-label, Randomized, Parallel Controlled Study Completed NCT00964496 Phase 2 Thalidomide;Iron
5 Hypertension Disorders During Pregnancy and Multi-exposure to Environmental Noise and Atmospheric Pollution in an Urban Setting: Case-control Study in Women Who Gave Birth at Dijon and Besançon CHUs Between 2005 and 2009 Unknown status NCT03261245
6 Efficacy of Narrow Band Spectrum Endoscopy Versus Histopathology for the Diagnosis of Gastric Antral Vascular Ectasia in Patients With Liver Cirrhosis Completed NCT04388150
7 Chronic Headache and Chronic Backache Following Unintentional Dural Puncture at Delivery Room Completed NCT03908424
8 Prospective Evaluation Of Outcomes For Patients Undergoing Radiofrequency Ablation (RFA) Using HALO Ultra Device For Gastric Antral Vascular Ectasia (GAVE) Recruiting NCT03525366
9 THE EFFECT OF AFTER CAESARIAN SECTION HAND MASSAGE ON PAIN, COMFORT LEVEL AND GAS OUTPUT TIME Enrolling by invitation NCT05521581
10 Endoscopic Band Ligation Versus Argon Plasma Coagulation in Management of Gastric Antral Vascular Ectasia; Randomized Clinical Trial Not yet recruiting NCT05258604
11 Gastric Antral Vascular Ectasia Treatment With Balloon Cryotherapy: A Multicenter Prospective Trial Suspended NCT04760873

Search NIH Clinical Center for Gastric Antral Vascular Ectasia

Cochrane evidence based reviews: gastric antral vascular ectasia

Genetic Tests for Gastric Antral Vascular Ectasia

Anatomical Context for Gastric Antral Vascular Ectasia

Organs/tissues related to Gastric Antral Vascular Ectasia:

MalaCards : Liver, Bone Marrow, Skeletal Muscle, Brain, Breast, Spinal Cord, Smooth Muscle

Publications for Gastric Antral Vascular Ectasia

Articles related to Gastric Antral Vascular Ectasia:

(show top 50) (show all 30310)
# Title Authors PMID Year
1
A case of gastric antral vascular ectasia in which PuraStat, a novel self-assembling peptide hemostatic hydrogel, was effective. 62
36381641 2023
2
Exploring Mothers' Perspectives About Why Grandparents in Appalachia Give Their Grandchildren Cariogenic Foods and Beverages: A Qualitative Study. 62
35395420 2022
3
"Even God Gave up on Them": A Deconstruction of Homosexuality Discourses in Zimbabwe's Online Locales. 62
34185625 2022
4
Factors associated with utilization of modern postpartum family planing methods during the extended postpartum period among mothers who gave birth in the last 12 months at Injibara town, Northwest, Ethiopia: a cross-sectional study. 62
36457131 2022
5
Early diagnosis and treatment of Alzheimer's disease by targeting toxic soluble Aβ oligomers. 62
36442093 2022
6
Peripheral Arterial Disease Located in the Feet of Patients With Diabetes and Foot Ulceration Demands a New Approach to the Assessment of Ischemia. 62
32806976 2022
7
A Mixed-methods Assessment of the Impact of Insurance Issues on the Emotional and Physical Health of Patients With Inflammatory Bowel Disease. 62
35191977 2022
8
Pregnancy outcomes after abdominal sacrocervicopexy. 62
35716198 2022
9
Evidence for entropy maximisation in human free choice behaviour. 62
36463639 2022
10
Synthesis and hydrolysis of monocarbamate from allylic 1,4-dicarbamate: Bis-homodichloroinositol. 62
36166876 2022
11
Sonographic Assessment of Acute Versus Chronic Cholecystitis: An Ultrasound Probability Stratification Model. 62
36457230 2022
12
Determinants of cervical cancer screening service utilization among women attending healthcare services in Amhara region referral hospitals: a case-control study. 62
36461054 2022
13
Improved Tumor Responses with Sequential Targeted α-Particles Followed by Interleukin 2 Immunocytokine Therapies in Treatment of CEA-Positive Breast and Colon Tumors in CEA Transgenic Mice. 62
35772959 2022
14
Study of 400 MHz microwave conduction loss effect for a hydrolysis reaction by thermostable β-Glucosidase HT1. 62
36472549 2022
15
Decontamination of Fuchsin dye by carboxymethyl cellulose-graft-poly(acrylic acid-co-itaconic acid)/carbon black nanocomposite hydrogel. 62
36228810 2022
16
The application of single beta-human chorionic gonadotropin (β-hCG) level measurement in women undergoing single blastocyst transfer. 62
36279733 2022
17
Machine learning-based sensor array: full and reduced fluorescence data for versatile analyte detection based on gold nanocluster as a single probe. 62
36280626 2022
18
Handling of the Covid-19 Pandemic and Its Effects on Bariatric Surgical Practice: Analysis of GENEVA Study Database. 62
36282429 2022
19
Perinatal outcomes of women with gestational breast cancer in Australia and New Zealand: A prospective population-based study. 62
35470904 2022
20
Expectations of the upcoming birth - A survey of women's self-efficacy and birth positions. 62
36244077 2022
21
Kinetics of chromium(V)-oxo and chromium(IV)-oxo porphyrins: Reactivity and mechanism for sulfoxidation reactions. 62
36162208 2022
22
Synthesis of Chrysoporphyrins and a Related Benzopyrene-Fused System. 62
36459435 2022
23
Reaction of 7α-bromo-6-nitrocholest-5-enes with hydrazine: Formation of steroidal pyrazolines and molecular docking against SARS-CoV-2 omicron protease. 62
36208699 2022
24
The effects of COVID-19 restrictions and other perinatal factors on women's sense of control during childbirth: a prospective cohort study. 62
35320020 2022
25
Word definition skills in elementary school children - The contribution of bilingualism, cognitive factors, and social factors. 62
34802353 2022
26
Unpacking cesarean in rural Bangladesh: Who, what, when, and where. 62
35347769 2022
27
Limitation of standard pseudoisochromatic plates in identifying colour vision deficiencies when compared with genetic testing. 62
35113505 2022
28
Is there a benefit of antenatal corticosteroid when given < 48 h before delivery? 62
35099594 2022
29
Antifungal and antibacterial activity of marine sponges from Ratnagiri coast of India. 62
35759971 2022
30
Interactions between lead(II) ions and dissolved organic matter derived from organic fertilizers incubated in the field. 62
35654518 2022
31
Degradation of Azithromycin from aqueous solution using Chlorine-ferrous- oxidation: ANN-GA modeling and Daphnia magna biotoxicity test assessment. 62
35977588 2022
32
A Machine Learning-Based Intrauterine Growth Restriction (IUGR) Prediction Model for Newborns. 62
35941474 2022
33
An investigation into gender bias in the evaluation of orthopedic trainee arthroscopic skills. 62
35788056 2022
34
Selective and ultrasensitive citric acid assay in urine samples using a MWCNT/Fe3O4 nanoparticle-modified carbon paste electrode. 62
36278282 2022
35
Methodological guidelines: Cow milk mid-infrared spectra to predict reference enteric methane data collected by an automated head-chamber system. 62
36175234 2022
36
Total Synthesis of Alcyonolide. 62
36326030 2022
37
Influence of the type of electrodes in the assessment of body composition by bioelectrical impedance analysis in the supine position. 62
36215865 2022
38
Sharp dose profiles for high precision proton therapy using strongly focused proton beams. 62
36344543 2022
39
Effects of Strategic Supplementation with Lupinus angustifolius and Avena sativa Grains on Colostrum Quality and Passive Immunological Transfer to Newborn Lambs. 62
36428387 2022
40
One-Bond 13C-1H and 13C-13C Spin-Coupling Constants as Constraints in MA'AT Analysis of Saccharide Conformation. 62
36356177 2022
41
Measuring recognition visual acuity in young children - testability with the Waterloo Differential Acuity Test (WatDAT). 62
36403264 2022
42
Analysis of the binding of warfarin to glyoxal- and methylglyoxal-modified human serum albumin by ultrafast affinity extraction. 62
36272357 2022
43
Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review. 62
36204816 2022
44
Multi-Glycomic Characterization of Fiber from AOAC Methods Defines the Carbohydrate Structures. 62
36382383 2022
45
Identifying steep pareto fronts in multicomponent adsorption using a novel elliptical method. 62
35716298 2022
46
Evaluation of the practical clinical use of the Horse Grimace Scale translated into French. 62
36008265 2022
47
Nutrition education in medical schools (NEMS) project: Promoting clinical nutrition in medical schools - Perspectives from different actors. 62
36473759 2022
48
The Impact of COVID-19 on the Monitoring of Pregnancy and Delivery of Pregnant Women in the Dominican Republic. 62
36421590 2022
49
Superconducting Properties of YBa2Cu3O7-δ with a Multiferroic Addition Synthesized by a Capping Agent-Aided Thermal Treatment Method. 62
36432245 2022
50
Does the COVID-19 Pandemic Affect Labor-Related Anxiety and Prevalence of Depressive Symptoms in Pregnant Women? 62
36362750 2022

Variations for Gastric Antral Vascular Ectasia

Expression for Gastric Antral Vascular Ectasia

Search GEO for disease gene expression data for Gastric Antral Vascular Ectasia.

Pathways for Gastric Antral Vascular Ectasia

GO Terms for Gastric Antral Vascular Ectasia

Biological processes related to Gastric Antral Vascular Ectasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium ion export across plasma membrane GO:0036376 9.46 ATP4A ATP12A
2 cellular potassium ion homeostasis GO:0030007 9.26 ATP4A ATP12A
3 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.92 ATP4A ATP12A

Molecular functions related to Gastric Antral Vascular Ectasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 P-type sodium:potassium-exchanging transporter activity GO:0005391 9.46 ATP4A ATP12A
2 P-type potassium transmembrane transporter activity GO:0008556 8.96 ATP4A ATP12A
3 P-type potassium:proton transporter activity GO:0008900 8.92 ATP4A ATP12A

Sources for Gastric Antral Vascular Ectasia

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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