MCID: GST041
MIFTS: 20

Gastric Cardia Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Cardia Carcinoma

MalaCards integrated aliases for Gastric Cardia Carcinoma:

Name: Gastric Cardia Carcinoma 12 15 17 70
Carcinoma of Cardia of Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6270
NCIt 50 C6794
UMLS 70 C1333763

Summaries for Gastric Cardia Carcinoma

MalaCards based summary : Gastric Cardia Carcinoma, also known as carcinoma of cardia of stomach, is related to cardia cancer and gastric cardia adenocarcinoma. An important gene associated with Gastric Cardia Carcinoma is XRCC1 (X-Ray Repair Cross Complementing 1). Related phenotypes are Decreased viability and Decreased viability

Related Diseases for Gastric Cardia Carcinoma

Diseases related to Gastric Cardia Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 cardia cancer 30.0 XRCC1 MTHFR
2 gastric cardia adenocarcinoma 29.5 NEDD4 MTHFR
3 adenosquamous carcinoma 10.0
4 pelvic inflammatory disease 9.9 CTSB CDH1
5 gastroesophageal adenocarcinoma 9.8 XRCC1 MTHFR
6 cleft lip with or without cleft palate 9.8 MTHFR CDH1
7 cleft lip/palate 9.7 MTHFR CDH1
8 differentiated thyroid carcinoma 9.7 XRCC1 MTHFR
9 colorectal adenoma 9.6 XRCC1 MTHFR CDH1
10 mucositis 9.6 XRCC1 MTHFR

Graphical network of the top 20 diseases related to Gastric Cardia Carcinoma:



Diseases related to Gastric Cardia Carcinoma

Symptoms & Phenotypes for Gastric Cardia Carcinoma

GenomeRNAi Phenotypes related to Gastric Cardia Carcinoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00055-A-1 9.5 CTSB KISS1 TNK2
2 Decreased viability GR00055-A-2 9.5 CTSB KISS1 TNK2
3 Decreased viability GR00221-A-1 9.5 TNK2
4 Decreased viability GR00221-A-2 9.5 TNK2
5 Decreased viability GR00221-A-3 9.5 TNK2
6 Decreased viability GR00221-A-4 9.5 TNK2
7 Decreased viability GR00249-S 9.5 CTSB KISS1
8 Decreased viability GR00381-A-1 9.5 KISS1 TNK2
9 Decreased viability GR00402-S-2 9.5 KISS1

Drugs & Therapeutics for Gastric Cardia Carcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Cardia Carcinoma

Genetic Tests for Gastric Cardia Carcinoma

Anatomical Context for Gastric Cardia Carcinoma

Publications for Gastric Cardia Carcinoma

Articles related to Gastric Cardia Carcinoma:

(show all 40)
# Title Authors PMID Year
1
Oral leukoplakia and the long-term risk of upper gastrointestinal cancer deaths in the Linxian dysplasia population. 61
32808454 2020
2
Fresh fruit consumption may decrease the long-term risk of esophageal cancer mortality: A 30-year follow-up study in the Linxian Dysplasia Nutrition Intervention trial (NIT). 61
32469462 2020
3
Body mass index and risk of upper gastrointestinal cancer: A 30-year follow-up of the Linxian dysplasia nutrition intervention trial cohort. 61
32045872 2020
4
Characterization of 500 Chinese patients with cervical esophageal cancer by clinicopathological and treatment outcomes. 61
32296589 2020
5
Site-Specific Variation in Familial Cancer as Suggested by Family History, Multiple Primary Cancer, Age at Onset, and Sex Ratio Associated With Upper, Middle, and Lower Third Esophageal and Gastric Cardia Carcinoma. 61
33194702 2020
6
[Seven-Year Follow-Up of Advanced Gastric Carcinoma Treated Only with Chemotherapy Considering the Macroscopic Findings]. 61
31501375 2019
7
Efficacy of trastuzumab combined with cisplatin and docetaxel on gastric cardia carcinoma and its influence on HER2 and cyclin D1 expressions. 61
31282137 2019
8
Association between tooth loss and upper gastrointestinal cancer: A 30-year follow-up of the Linxian Dysplasia Nutrition Intervention Trial Cohort. 61
30883021 2019
9
Association between oral leukoplakia and risk of upper gastrointestinal cancer death: A follow-up study of the Linxian General Population Trial. 61
28929584 2017
10
Characterization of tissue chromogranin A (CgA) immunostaining and clinicohistopathological changes for the 125 Chinese patients with primary small cell carcinoma of the esophagus. 61
28575250 2017
11
Proportion of cancer in a Middle eastern country attributable to established risk factors. 61
28521815 2017
12
[Is invasive therapy (medically/ethically) justifiable nearing an end of life situation, if it is based on symptom control and quality of life?]. 61
25113105 2014
13
Delayed gastric emptying after esophagectomy for malignancy. 61
24742329 2014
14
Coexistence of gastrointestinal stromal tumor, esophageal and gastric cardia carcinomas. 61
23569349 2013
15
Double contrast-enhanced two-dimensional and three-dimensional ultrasonography for evaluation of gastric lesions. 61
22919245 2012
16
Increased incidence and survival for oesophageal cancer but not for gastric cardia cancer in the Netherlands. 61
22317953 2012
17
Association of DNA repair gene XRCC1 and XPD polymorphisms with genetic susceptibility to gastric cancer in a Chinese population. 61
20863780 2011
18
Comparison of anastomotic leakage and stricture formation following layered and stapler oesophagogastric anastomosis for cancer: a prospective randomized controlled trial. 61
20233534 2010
19
Gastric cardia carcinoma is associated with the promoter -77T>C gene polymorphism of X-ray cross-complementing group 1 (XRCC1). 61
19662459 2009
20
[Analysis of the changing trends of frequency and localization of gastric cancers arising from different sites of the stomach in population of the high incidence area of esophageal and gastric cancers in Hebei province]. 61
19173825 2008
21
Clinical application of layered anastomosis during esophagogastrostomy. 61
18210181 2008
22
[Expression and clinical significance of KiSS-1 and E-cadherin in gastric cardia carcinoma]. 61
17659469 2007
23
A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors. 61
17324405 2007
24
Genetic polymorphisms in folate- metabolizing enzymes and risk of gastroesophageal cancers: a potential nutrient-gene interaction in cancer development. 61
17684410 2007
25
[Clinical analysis of 123 gastric cardia carcinoma patients treated with surgical operation]. 61
16405761 2006
26
Nutrition in the prevention of gastrointestinal cancer. 61
16782531 2006
27
Clinicopathologic and protein expression differences between cardia carcinoma and noncardia carcinoma of the stomach. 61
15726543 2005
28
E-cadherin expression as predictive marker of proximal resection line involvement for advanced carcinoma of the gastric cardia. 61
15522555 2004
29
Marked multi-ethnic variation of esophageal and gastric cardia carcinomas within the United States. 61
15089886 2004
30
Unchanging trend of adenocarcinoma of the esophagus and gastric cardia in Taiwan: a 15-year experience in a single center. 61
11991601 2002
31
Relationship between anal occult blood and hepatobiliary pancreatic carcinoma screening. 61
10830581 2000
32
Rising incidence of esophageal adenocarcinoma in Western countries: is it possible to identify a population at risk? 61
11284973 2000
33
[Analysis of patients survived over ten years after resection of gastric cardia carcinoma]. 61
11776860 1999
34
Survival of proximal third gastric carcinoma. 61
9701212 1998
35
[Surgical treatment for carcinoma of gastric stump--a report on 13 patients]. 61
1618080 1992
36
[Resection of esophageal and gastric cardiac cancer and esophagogastrostomy by planting esophagus into the stomach: a report of cases]. 61
2086092 1990
37
[Epidemiologic investigation of carcinoma of the esophagus and gastric cardia carcinoma in Nanao County, Guangdong province]. 61
3757739 1986
38
Infusional chemotherapy and cyclic radiation therapy in inoperable esophageal and gastric cardia carcinoma. 61
6829494 1983
39
MODIFICATIONS IN THE ORGANISM FOLLOWING REMOVAL OF GASTRIC CARDIA CARCINOMA AND METHODS OF THEIR COMPENSATION. 61
14103916 1963
40
Carcinoma of cardia of stomach. 61
20983884 1946

Variations for Gastric Cardia Carcinoma

Expression for Gastric Cardia Carcinoma

Search GEO for disease gene expression data for Gastric Cardia Carcinoma.

Pathways for Gastric Cardia Carcinoma

GO Terms for Gastric Cardia Carcinoma

Cellular components related to Gastric Cardia Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 perinuclear region of cytoplasm GO:0048471 8.92 TNK2 NEDD4 CTSB CDH1

Biological processes related to Gastric Cardia Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to organic substance GO:0010033 8.96 XRCC1 CDH1
2 response to drug GO:0042493 8.8 XRCC1 MTHFR CDH1

Sources for Gastric Cardia Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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