MCID: GST042
MIFTS: 26

Gastric Diffuse Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Diffuse Adenocarcinoma

MalaCards integrated aliases for Gastric Diffuse Adenocarcinoma:

Name: Gastric Diffuse Adenocarcinoma 12 15
Carcinoma, Diffuse Type 12 73
Adenocarcinoma of Linitis Plastica Type 12
Diffuse Type Adenocarcinoma 12
Diffuse Type Carcinoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6217
NCIt 50 C4127 C9159
SNOMED-CT 68 24505004

Summaries for Gastric Diffuse Adenocarcinoma

MalaCards based summary : Gastric Diffuse Adenocarcinoma, also known as carcinoma, diffuse type, is related to goblet cell carcinoid and morpheaform basal cell carcinoma. An important gene associated with Gastric Diffuse Adenocarcinoma is CDH1 (Cadherin 1), and among its related pathways/superpathways are Cytoskeletal Signaling and Arf6 trafficking events.

Related Diseases for Gastric Diffuse Adenocarcinoma

Diseases related to Gastric Diffuse Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 goblet cell carcinoid 10.7 CDH1 KRT20
2 morpheaform basal cell carcinoma 10.7 CDH1 KRT20
3 villous adenoma 10.6 CDX2 KRT20
4 chronic cholangitis 10.5 CDX2 MMP15
5 renal pelvis adenocarcinoma 10.5 CDH1 KRT7
6 cystic basal cell carcinoma 10.5 KRT20 KRT7
7 seminal vesicle adenocarcinoma 10.5 KRT20 KRT7
8 transverse colon cancer 10.5 KRT20 KRT7
9 ovarian large-cell neuroendocrine carcinoma 10.5 KRT20 KRT7
10 eyelid neoplasm 10.5 KRT20 KRT7
11 malignant syringoma 10.5 KRT20 KRT7
12 krukenberg carcinoma 10.5 KRT20 KRT7
13 lung acinar adenocarcinoma 10.5 KRT20 KRT7
14 small cell carcinoma of the bladder 10.5 KRT20 KRT7
15 eccrine sweat gland neoplasm 10.5 KRT20 KRT7
16 ovary neuroendocrine neoplasm 10.5 CDX2 KRT7
17 vulval paget's disease 10.5 KRT20 KRT7
18 bile duct cystadenocarcinoma 10.5 KRT20 KRT7
19 intratubular embryonal carcinoma 10.5 KRT20 KRT7
20 mucinous adenofibroma 10.5 CDX2 KRT7
21 anus adenocarcinoma 10.5 CDX2 KRT7
22 meibomian cyst 10.4 KRT20 KRT7
23 bladder lymphoma 10.4 KRT20 KRT7
24 papillary serous adenocarcinoma 10.4 KRT20 KRT7
25 breast adenomyoepithelioma 10.4 CDH1 KRT7
26 breast myoepithelial neoplasm 10.4 CDH1 KRT7
27 epithelial predominant wilms' tumor 10.4 CDX2 KRT7
28 intestinal benign neoplasm 10.4 CDH1 CDX2
29 medulloepithelioma 10.4 KRT20 KRT7
30 glycogen-rich clear cell breast carcinoma 10.4 KRT20 KRT7
31 renal pelvis carcinoma 10.4 KRT20 KRT7
32 paget disease, extramammary 10.4 KRT20 KRT7
33 bronchiolo-alveolar adenocarcinoma 10.4 CDX2 KRT7
34 mucinous cystadenocarcinoma 10.4 KRT20 KRT7
35 nasal cavity adenocarcinoma 10.4 CDX2 KRT7
36 mucinous ovarian cystadenoma 10.4 CDX2 KRT7
37 anal canal adenocarcinoma 10.4 CDX2 KRT7
38 dermoid cyst 10.4 KRT20 KRT7
39 immune system organ benign neoplasm 10.4 KRT20 KRT7
40 thymus lipoma 10.4 KRT20 KRT7
41 cystadenofibroma 10.4 KRT20 KRT7
42 inverted papilloma 10.4 KRT20 KRT7
43 ovarian cystic teratoma 10.4 KRT20 KRT7
44 pancreatic mucinous cystadenoma 10.4 KRT20 KRT7
45 large cell neuroendocrine carcinoma 10.3 KRT20 KRT7
46 corneal dystrophy, posterior polymorphous, 3 10.3 CDH1 KRT7
47 biliary tract neoplasm 10.3 CDX2 KRT7
48 duodenum cancer 10.3 CDX2 KRT7
49 mammary paget's disease 10.3 KRT20 KRT7
50 papillary adenocarcinoma 10.3 CDH1 KRT7

Graphical network of the top 20 diseases related to Gastric Diffuse Adenocarcinoma:



Diseases related to Gastric Diffuse Adenocarcinoma

Symptoms & Phenotypes for Gastric Diffuse Adenocarcinoma

Drugs & Therapeutics for Gastric Diffuse Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Diffuse Adenocarcinoma

Genetic Tests for Gastric Diffuse Adenocarcinoma

Anatomical Context for Gastric Diffuse Adenocarcinoma

Publications for Gastric Diffuse Adenocarcinoma

Articles related to Gastric Diffuse Adenocarcinoma:

# Title Authors Year
1
Reduced MUTYH, MTH1, and OGG1 expression and TP53 mutation in diffuse-type adenocarcinoma of gastric cardia. ( 26980051 )
2016

Variations for Gastric Diffuse Adenocarcinoma

Expression for Gastric Diffuse Adenocarcinoma

Search GEO for disease gene expression data for Gastric Diffuse Adenocarcinoma.

Pathways for Gastric Diffuse Adenocarcinoma

GO Terms for Gastric Diffuse Adenocarcinoma

Cellular components related to Gastric Diffuse Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 catenin complex GO:0016342 8.96 CDH1 CTNNA1
2 flotillin complex GO:0016600 8.62 CDH1 CTNNA1

Biological processes related to Gastric Diffuse Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 adherens junction organization GO:0034332 8.96 CDH1 CTNNA1
2 cellular response to indole-3-methanol GO:0071681 8.62 CDH1 CTNNA1

Molecular functions related to Gastric Diffuse Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cadherin binding GO:0045296 9.13 CDH1 CTNNA1 RAB11B
2 gamma-catenin binding GO:0045295 8.62 CDH1 CTNNA1

Sources for Gastric Diffuse Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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