MCID: GST007
MIFTS: 32

Gastric Dilatation

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastric Dilatation

MalaCards integrated aliases for Gastric Dilatation:

Name: Gastric Dilatation 12 45 15 74
Stomach Dilatation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3229
MeSH 45 D013271
UMLS 74 C0038353

Summaries for Gastric Dilatation

MalaCards based summary : Gastric Dilatation, also known as stomach dilatation, is related to intestinal volvulus and anorexia nervosa. An important gene associated with Gastric Dilatation is MANBA (Mannosidase Beta), and among its related pathways/superpathways are Metabolism and Lysosome. The drugs Erythritol and Vasodilator Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and kidney.

Related Diseases for Gastric Dilatation

Diseases related to Gastric Dilatation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 intestinal volvulus 10.8
2 anorexia nervosa 10.3
3 superior mesenteric artery syndrome 10.2
4 ischemia 10.1
5 eating disorder 10.1
6 bulimia nervosa 10.0
7 acute pancreatitis 10.0
8 pancreatitis 10.0
9 muscular dystrophy 10.0
10 prader-willi syndrome 9.9
11 pyloric stenosis 9.9
12 gastritis 9.9
13 compartment syndrome 9.9
14 mucopolysaccharidosis, type vii 9.9 GLB1 MANBA
15 gastroschisis 9.9
16 meconium ileus 9.9
17 leptin deficiency or dysfunction 9.9
18 respiratory failure 9.9
19 autonomic neuropathy 9.9
20 duodenal ulcer 9.9
21 peritonitis 9.9
22 intestinal obstruction 9.9
23 neuropathy 9.9
24 abdominal wall defect 9.9
25 cervical cancer 9.8
26 lysosomal storage disease 9.7 GLB1 MANBA
27 hernia, hiatus 9.7
28 systemic lupus erythematosus 9.7
29 pyloric stenosis, infantile hypertrophic, 1 9.7
30 duodenal atresia 9.7
31 myeloma, multiple 9.7
32 muscular dystrophy, duchenne type 9.7
33 gastrointestinal stromal tumor 9.7
34 porphyria, acute hepatic 9.7
35 cerebral palsy 9.7
36 diabetes mellitus 9.7
37 glomerulonephritis 9.7
38 hepatitis 9.7
39 renal tubular acidosis 9.7
40 inflammatory bowel disease 9.7
41 atrioventricular block 9.7
42 third-degree atrioventricular block 9.7
43 limb ischemia 9.7
44 cardiac arrest 9.7
45 rickets 9.7
46 gastric ulcer 9.7
47 megacolon 9.7
48 pulmonary edema 9.7
49 diabetic autonomic neuropathy 9.7
50 gastroparesis 9.7

Graphical network of the top 20 diseases related to Gastric Dilatation:



Diseases related to Gastric Dilatation

Symptoms & Phenotypes for Gastric Dilatation

Drugs & Therapeutics for Gastric Dilatation

Drugs for Gastric Dilatation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Erythritol Not Applicable 149-32-6, 2418-52-2 169019
2 Vasodilator Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Invasive and Non Invasive Mechanical Ventilation on Feeding Delivery in COPD Elderly Patients Unknown status NCT00417755
2 Gastric Volumetry by Gastric Tomodensitometry With Gas Completed NCT01963637 Not Applicable
3 Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children Completed NCT02016703 Not Applicable

Search NIH Clinical Center for Gastric Dilatation

Cochrane evidence based reviews: gastric dilatation

Genetic Tests for Gastric Dilatation

Anatomical Context for Gastric Dilatation

MalaCards organs/tissues related to Gastric Dilatation:

42
Lung, Testes, Kidney, Liver, Colon

Publications for Gastric Dilatation

Articles related to Gastric Dilatation:

(show top 50) (show all 358)
# Title Authors Year
1
Acute gastric dilatation and ischemia associated with portal vein gas caused by binge eating. ( 29132202 )
2019
2
Extensive gastric necrosis secondary to acute gastric dilatation: A case report. ( 30448603 )
2019
3
Transient distal renal tubular acidosis in a dog with gastric-dilatation-volvulus. ( 30705453 )
2019
4
Fetal Primary Small Bowel Volvulus Associated with Acute Gastric Dilatation Detected by Ultrasonography. ( 30728342 )
2019
5
Gastric Necrosis and Perforation Following Massive Gastric Dilatation in an Adolescent Girl: A Rare Cause of Acute Abdomen. ( 30761307 )
2019
6
Serial evaluation of serum total reduction power potential by cyclic voltammetry in 30 dogs with gastric dilatation and volvulus- a randomised, controlled (lidocaine vs placebo), clinical trial. ( 29202314 )
2018
7
A Rare Cause and Complication of Acute Gastric Dilatation: Superior Mesenteric Artery Syndrome and Perforation. ( 29531498 )
2018
8
Prehospital Care of Canine Gastric Dilatation and Volvulus. ( 29533441 )
2018
9
Acute gastric dilatation in a patient with lupus nephritis: An uncommon presentation of lupus mesenteric vasculitis. ( 29657215 )
2018
10
Cell-Free DNA, High-Mobility Group Box-1, and Procalcitonin Concentrations in Dogs With Gastric Dilatation-Volvulus Syndrome. ( 29686994 )
2018
11
The canine gut microbiome is associated with higher risk of gastric dilatation-volvulus and high risk genetic variants of the immune system. ( 29889838 )
2018
12
Acute Massive Gastric Dilatation in a Patient with an Eating Disorder. ( 29491312 )
2018
13
Spontaneous gastric dilatation-volvulus in two cats. ( 29906334 )
2018
14
A Prospective Evaluation of a Modified Belt-Loop Gastropexy in 100 Dogs with Gastric Dilatation-Volvulus. ( 30040446 )
2018
15
Gastric dilatation and enterotoxemia in ten captive felids. ( 30211645 )
2018
16
Prognostic value of canine pancreatic lipase immunoreactivity and lipase activity in dogs with gastric dilatation-volvulus. ( 30226861 )
2018
17
Massive gastric dilatation leading to acute respiratory distress 1 year after a Nissen fundoplication. ( 30262534 )
2018
18
Comparison of saphenous and cephalic blood lactate concentrations in dogs with gastric dilatation and volvulus: 45 cases. ( 30363379 )
2018
19
Diagnosis of chronic gastric instability using computed tomography in a Great Dane that progressed to gastric dilatation and volvulus: a literature review and case report. ( 30425956 )
2018
20
Gastric Dilatation and Abdominal Compartment Syndrome in a Child with Prader-Willi Syndrome. ( 28588153 )
2017
21
Acute gastric dilatation in a bulimic patient. ( 26975234 )
2017
22
Unexpected Death Due to Acute Gastric Dilatation and Gastric Necrosis in an 11-Year-Old Boy. ( 27164319 )
2017
23
Portal vein gas secondary to acute non-obstructive gastric dilatation. ( 27916447 )
2017
24
Modified tube gastropexy using a mushroom-tipped silicone catheter for management of gastric dilatation-volvulus in dogs. ( 28160305 )
2017
25
Acute massive gastric dilatation causing ischaemic necrosis and perforation of the stomach. ( 28619737 )
2017
26
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5. ( 28738011 )
2017
27
GASTRIC DILATATION VOLVULUS IN ADULT MANED WOLVES (CHRYSOCYON BRACHYURUS). ( 28749303 )
2017
28
Gastric Dilatation Associated with Gastric Colonization with Sarcina-Like Bacteria in a Cat with Chronic Enteritis. ( 28892423 )
2017
29
Evaluation of echocardiography and cardiac biomarker concentrations in dogs with gastric dilatation volvulus. ( 28960715 )
2017
30
Acute gastric dilatation due to binge eating may be fatal. ( 28971182 )
2017
31
Acute gastric dilatation after dietary violation. ( 29082742 )
2017
32
Differentiating between food bloat and gastric dilatation and volvulus in dogs. ( 29175931 )
2017
33
Incidence of gastric dilatation-volvulus following a splenectomy in 238 dogs. ( 29203936 )
2017
34
Massive gastric dilatation: the radiological picture of eating disorder. ( 27041386 )
2017
35
Use of a venting PEG tube in the management of recurrent acute gastric dilatation associated with Prader-Willi syndrome. ( 26763981 )
2016
36
Binge Eating Leading to Acute Gastric Dilatation, Ischemic Necrosis and Rupture -A Case Report. ( 27134932 )
2016
37
Temporary percutaneous T-fastener gastropexy and continuous decompressive gastrostomy in dogs with experimentally induced gastric dilatation. ( 27347832 )
2016
38
Dobutamine stress echocardiography resulting in acute gastric dilatation and pneumoporta. ( 27388544 )
2016
39
Pyloric localisation in 57 dogs of breeds susceptible to gastric dilatation-volvulus in the UK using computed tomography. ( 27784838 )
2016
40
Gastric dilatation and intestinal obstruction mimicking acute coronary syndrome with dynamic electrocardiographic changes. ( 27899069 )
2016
41
Unanswered questions on gastric dilatation/volvulus and gastropexy. ( 27980146 )
2016
42
Rupture of gastrointestinal stromal tumor presenting with sudden onset chest and back pain and accompanied by gastric dilatation. ( 29123817 )
2016
43
Gastric dilatation volvulus: a retrospective study of 203 dogs with ventral midline gastropexy. ( 26459100 )
2016
44
Young Adult With Abdominal Pain. Gastric dilatation caused by anorexia nervosa. ( 26497441 )
2015
45
Severe gastric dilatation due to superior mesenteric artery syndrome in anorexia nervosa. ( 25639251 )
2015
46
What Is Your Diagnosis? Gastric dilatation-volvulus. ( 26594805 )
2015
47
Delayed Pneumoperitoneum and Acute Pulmonary Edema Secondary to Acute Gastric Dilatation. ( 26668807 )
2015
48
Acute gastric dilatation causing fatal outcome in a young female with eating disorder: a case report. ( 25844140 )
2015
49
Acute gastric dilatation in the context of bulimia nervosa. ( 26334471 )
2015
50
Acute massive gastric dilatation with abdominal compartment syndrome in a patient with bulimia nervosa. ( 26077071 )
2015

Variations for Gastric Dilatation

Expression for Gastric Dilatation

Search GEO for disease gene expression data for Gastric Dilatation.

Pathways for Gastric Dilatation

Pathways related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.2 ARSH GLB1 MANBA PNLIP UMPS
2 11.05 GLB1 MANBA
3 9.88 GLB1 MANBA

GO Terms for Gastric Dilatation

Cellular components related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysosomal lumen GO:0043202 8.62 GLB1 MANBA

Biological processes related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metabolic process GO:0008152 8.8 GLB1 MANBA UMPS

Molecular functions related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.26 ARSH GLB1 MANBA PNLIP
2 hydrolase activity, acting on glycosyl bonds GO:0016798 8.62 GLB1 MANBA

Sources for Gastric Dilatation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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