MCID: GST007
MIFTS: 33

Gastric Dilatation

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastric Dilatation

MalaCards integrated aliases for Gastric Dilatation:

Name: Gastric Dilatation 12 44 15 73
Stomach Dilatation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3229
MeSH 44 D013271
UMLS 73 C0038353

Summaries for Gastric Dilatation

MalaCards based summary : Gastric Dilatation, also known as stomach dilatation, is related to anorexia nervosa and superior mesenteric artery syndrome. An important gene associated with Gastric Dilatation is MANBA (Mannosidase Beta), and among its related pathways/superpathways are Lysosome and Gamma carboxylation, hypusine formation and arylsulfatase activation. The drugs Erythritol and Vasodilator Agents have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and liver, and related phenotype is behavior/neurological.

Related Diseases for Gastric Dilatation

Diseases related to Gastric Dilatation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 65)
# Related Disease Score Top Affiliating Genes
1 anorexia nervosa 10.2
2 superior mesenteric artery syndrome 10.0
3 ischemia 10.0
4 eating disorder 10.0
5 bulimia nervosa 9.9
6 hepatitis 9.9
7 duodenitis 9.9
8 pancreatitis 9.9
9 muscular dystrophy 9.9
10 pyloric stenosis 9.8
11 acute pancreatitis 9.8
12 compartment syndrome 9.8
13 cardiac arrhythmia 9.7
14 prader-willi syndrome 9.7
15 gastroschisis 9.7
16 morbid obesity 9.7
17 gastric ulcer 9.7
18 respiratory failure 9.7
19 autonomic neuropathy 9.7
20 duodenal ulcer 9.7
21 cerebritis 9.7
22 laryngitis 9.7
23 gastritis 9.7
24 peritonitis 9.7
25 intestinal obstruction 9.7
26 neuropathy 9.7
27 cervical cancer 9.7
28 hernia, hiatus 9.6
29 duodenal atresia 9.6
30 myeloma, multiple 9.6
31 muscular dystrophy, duchenne type 9.6
32 aging 9.6
33 porphyria, acute hepatic 9.6
34 cerebral palsy 9.6
35 diabetes mellitus 9.6
36 inflammatory bowel disease 9.6
37 atrioventricular block 9.6
38 limb ischemia 9.6
39 cardiac arrest 9.6
40 salmonellosis 9.6
41 rickets 9.6
42 megacolon 9.6
43 pulmonary edema 9.6
44 diabetic autonomic neuropathy 9.6
45 gastroparesis 9.6
46 bronchopneumonia 9.6
47 hepatitis a 9.6
48 hypertrophic pyloric stenosis 9.6
49 megaesophagus 9.6
50 viral hepatitis 9.6

Graphical network of the top 20 diseases related to Gastric Dilatation:



Diseases related to Gastric Dilatation

Symptoms & Phenotypes for Gastric Dilatation

MGI Mouse Phenotypes related to Gastric Dilatation:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.02 MANBA TNNI3 ARSB GOLGB1 ITGB4

Drugs & Therapeutics for Gastric Dilatation

Drugs for Gastric Dilatation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Erythritol Not Applicable 149-32-6 222285
2 Vasodilator Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Invasive and Non Invasive Mechanical Ventilation on Feeding Delivery in COPD Elderly Patients Unknown status NCT00417755
2 Gastric Volumetry by Gastric Tomodensitometry With Gas Completed NCT01963637 Not Applicable
3 Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children Completed NCT02016703 Not Applicable

Search NIH Clinical Center for Gastric Dilatation

Cochrane evidence based reviews: gastric dilatation

Genetic Tests for Gastric Dilatation

Anatomical Context for Gastric Dilatation

MalaCards organs/tissues related to Gastric Dilatation:

41
Testes, Lung, Liver, Kidney, Colon

Publications for Gastric Dilatation

Articles related to Gastric Dilatation:

(show top 50) (show all 341)
# Title Authors Year
1
Cell-Free DNA, High-Mobility Group Box-1, and Procalcitonin Concentrations in Dogs With Gastric Dilatation-Volvulus Syndrome. ( 29686994 )
2018
2
A Rare Cause and Complication of Acute Gastric Dilatation: Superior Mesenteric Artery Syndrome and Perforation. ( 29531498 )
2018
3
Acute Massive Gastric Dilatation in a Patient with an Eating Disorder. ( 29491312 )
2018
4
Spontaneous gastric dilatation-volvulus in two cats. ( 29906334 )
2018
5
Acute gastric dilatation in a patient with lupus nephritis: An uncommon presentation of lupus mesenteric vasculitis. ( 29657215 )
2018
6
The canine gut microbiome is associated with higher risk of gastric dilatation-volvulus and high risk genetic variants of the immune system. ( 29889838 )
2018
7
Incidence of gastric dilatation-volvulus following a splenectomy in 238 dogs. ( 29203936 )
2017
8
Differentiating between food bloat and gastric dilatation and volvulus in dogs. ( 29175931 )
2017
9
Modified tube gastropexy using a mushroom-tipped silicone catheter for management of gastric dilatation-volvulus in dogs. ( 28160305 )
2017
10
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5. ( 28738011 )
2017
11
Gastric Dilatation and Abdominal Compartment Syndrome in a Child with Prader-Willi Syndrome. ( 28588153 )
2017
12
Serial evaluation of serum total reduction power potential by cyclic voltammetry in 30 dogs with gastric dilatation and volvulus- a randomised, controlled (lidocaine vs placebo), clinical trial. ( 29202314 )
2017
13
GASTRIC DILATATION VOLVULUS IN ADULT MANED WOLVES (CHRYSOCYON BRACHYURUS). ( 28749303 )
2017
14
Evaluation of echocardiography and cardiac biomarker concentrations in dogs with gastric dilatation volvulus. ( 28960715 )
2017
15
Acute massive gastric dilatation causing ischaemic necrosis and perforation of the stomach. ( 28619737 )
2017
16
Gastric Dilatation Associated with Gastric Colonization with Sarcina-like Bacteria in a Cat with Chronic Enteritis. ( 28892423 )
2017
17
Acute gastric dilatation and ischemia associated with portal vein gas caused by binge eating. ( 29132202 )
2017
18
Acute gastric dilatation after dietary violation. ( 29082742 )
2017
19
Massive gastric dilatation: the radiological picture of eating disorder. ( 27041386 )
2016
20
Unanswered questions on gastric dilatation/volvulus and gastropexy. ( 27980146 )
2016
21
Pyloric localisation in 57 dogs of breeds susceptible to gastric dilatation-volvulus in the UK using computed tomography. ( 27784838 )
2016
22
Unexpected Death Due to Acute Gastric Dilatation and Gastric Necrosis in an 11-Year-Old Boy. ( 27164319 )
2016
23
Binge Eating Leading to Acute Gastric Dilatation, Ischemic Necrosis and Rupture -A Case Report. ( 27134932 )
2016
24
Temporary percutaneous T-fastener gastropexy and continuous decompressive gastrostomy in dogs with experimentally induced gastric dilatation. ( 27347832 )
2016
25
Acute gastric dilatation in a bulimic patient. ( 26975234 )
2016
26
Portal vein gas secondary to acute non-obstructive gastric dilatation. ( 27916447 )
2016
27
Use of a venting PEG tube in the management of recurrent acute gastric dilatation associated with Prader-Willi syndrome. ( 26763981 )
2016
28
Gastric dilatation and intestinal obstruction mimicking acute coronary syndrome with dynamic electrocardiographic changes. ( 27899069 )
2016
29
Dobutamine stress echocardiography resulting in acute gastric dilatation and pneumoporta. ( 27388544 )
2016
30
Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid. ( 26457032 )
2015
31
C-reactive protein and high mobility group box 1 in dogs with gastric dilatation and volvulus. ( 26088834 )
2015
32
Suspicion of superior mesenteric artery syndrome in a patient with severe gastric dilatation after catheter ablation. ( 25786450 )
2015
33
Acute gastric dilatation in the context of bulimia nervosa. ( 26334471 )
2015
34
Severe gastric dilatation due to superior mesenteric artery syndrome in anorexia nervosa. ( 25639251 )
2015
35
Acute gastric dilatation in the context of bulimia nervosa. ( 26177084 )
2015
36
Delayed Pneumoperitoneum and Acute Pulmonary Edema Secondary to Acute Gastric Dilatation. ( 26668807 )
2015
37
Severe Acute Postoperative Gastric Dilatation. ( 26158257 )
2015
38
Gastrojejunostomy for pyloric stenosis after acute gastric dilatation due to overeating. ( 25663789 )
2015
39
Gastric dilatation volvulus: a retrospective study of 203 dogs with ventral midline gastropexy. ( 26459100 )
2015
40
Young Adult With Abdominal Pain. Gastric dilatation caused by anorexia nervosa. ( 26497441 )
2015
41
Hemostatic variables, plasma lactate concentration, and inflammatory biomarkers in dogs with gastric dilatation-volvulus. ( 26568318 )
2015
42
Acute massive gastric dilatation with abdominal compartment syndrome in a patient with bulimia nervosa. ( 26077071 )
2015
43
Acute gastric dilatation causing fatal outcome in a young female with eating disorder: a case report. ( 25844140 )
2015
44
What Is Your Diagnosis? Gastric dilatation-volvulus. ( 26594805 )
2015
45
Life-threatening acute gastric dilatation with aorta compression in a 3-year-old child. ( 26387581 )
2015
46
Massive gastric dilatation in bulimic patient. ( 25223115 )
2014
47
Prolonged idiopathic gastric dilatation following revascularization for chronic mesenteric ischemia. ( 24975870 )
2014
48
Inherited and predisposing factors in the development of gastric dilatation volvulus in dogs. ( 25496921 )
2014
49
Gastric dilatation and volvulus in a brachycephalic dog with hiatal hernia. ( 24871205 )
2014
50
Treatment of gastric dilatation in rabbits. ( 25103747 )
2014

Variations for Gastric Dilatation

Expression for Gastric Dilatation

Search GEO for disease gene expression data for Gastric Dilatation.

Pathways for Gastric Dilatation

GO Terms for Gastric Dilatation

Cellular components related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysosomal lumen GO:0043202 8.62 ARSB MANBA

Biological processes related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glycosphingolipid metabolic process GO:0006687 8.96 ARSB ARSH
2 metabolic process GO:0008152 8.92 ARSB ARSH MANBA UMPS

Molecular functions related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sulfuric ester hydrolase activity GO:0008484 8.96 ARSB ARSH
2 arylsulfatase activity GO:0004065 8.62 ARSB ARSH

Sources for Gastric Dilatation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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