MCID: GST007
MIFTS: 31

Gastric Dilatation

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastric Dilatation

MalaCards integrated aliases for Gastric Dilatation:

Name: Gastric Dilatation 12 44 15 73
Stomach Dilatation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3229
MeSH 44 D013271
UMLS 73 C0038353

Summaries for Gastric Dilatation

MalaCards based summary : Gastric Dilatation, also known as stomach dilatation, is related to anorexia nervosa and superior mesenteric artery syndrome. An important gene associated with Gastric Dilatation is MANBA (Mannosidase Beta), and among its related pathways/superpathways are Lysosome and Gamma carboxylation, hypusine formation and arylsulfatase activation. The drugs Vasodilator Agents and Erythritol have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and kidney, and related phenotype is Resistant to vaccinia virus (VACV-A4L) infection.

Related Diseases for Gastric Dilatation

Diseases related to Gastric Dilatation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)
# Related Disease Score Top Affiliating Genes
1 anorexia nervosa 10.3
2 superior mesenteric artery syndrome 10.2
3 intestinal volvulus 10.2
4 ischemia 10.1
5 eating disorder 10.1
6 bulimia nervosa 10.0
7 muscular dystrophy 10.0
8 pyloric stenosis 9.9
9 acute pancreatitis 9.9
10 gastritis 9.9
11 pancreatitis 9.9
12 compartment syndrome 9.9
13 lysosomal storage disease 9.8 ARSB MANBA
14 prader-willi syndrome 9.8
15 gastroschisis 9.8
16 morbid obesity 9.8
17 respiratory failure 9.8
18 autonomic neuropathy 9.8
19 duodenal ulcer 9.8
20 intestinal obstruction 9.8
21 neuropathy 9.8
22 mucopolysaccharidosis, type vi 9.8 ARSB ARSH
23 mucopolysaccharidosis-plus syndrome 9.8 ARSB ARSH
24 multiple sulfatase deficiency 9.8 ARSB ARSH
25 cervical cancer 9.8
26 metachromatic leukodystrophy 9.8 ARSB ARSH
27 hernia, hiatus 9.7
28 systemic lupus erythematosus 9.7
29 duodenal atresia 9.7
30 myeloma, multiple 9.7
31 muscular dystrophy, duchenne type 9.7
32 gastrointestinal stromal tumor 9.7
33 porphyria, acute hepatic 9.7
34 cerebral palsy 9.7
35 diabetes mellitus 9.7
36 hepatitis 9.7
37 inflammatory bowel disease 9.7
38 atrioventricular block 9.7
39 limb ischemia 9.7
40 cardiac arrest 9.7
41 rickets 9.7
42 gastric ulcer 9.7
43 megacolon 9.7
44 pulmonary edema 9.7
45 diabetic autonomic neuropathy 9.7
46 gastroparesis 9.7
47 bronchopneumonia 9.7
48 hepatitis a 9.7
49 hypertrophic pyloric stenosis 9.7
50 megaesophagus 9.7

Graphical network of the top 20 diseases related to Gastric Dilatation:



Diseases related to Gastric Dilatation

Symptoms & Phenotypes for Gastric Dilatation

GenomeRNAi Phenotypes related to Gastric Dilatation according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Resistant to vaccinia virus (VACV-A4L) infection GR00351-A-1 8.92 ARSB MANBA PNLIP TNNI3

Drugs & Therapeutics for Gastric Dilatation

Drugs for Gastric Dilatation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vasodilator Agents Not Applicable
2
Erythritol Not Applicable 149-32-6 222285

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Invasive and Non Invasive Mechanical Ventilation on Feeding Delivery in COPD Elderly Patients Unknown status NCT00417755
2 Gastric Volumetry by Gastric Tomodensitometry With Gas Completed NCT01963637 Not Applicable
3 Gastrointestinal Tolerance of Erythritol-containing Beverages in Young Children Completed NCT02016703 Not Applicable

Search NIH Clinical Center for Gastric Dilatation

Cochrane evidence based reviews: gastric dilatation

Genetic Tests for Gastric Dilatation

Anatomical Context for Gastric Dilatation

MalaCards organs/tissues related to Gastric Dilatation:

41
Lung, Testes, Kidney, Liver, Colon

Publications for Gastric Dilatation

Articles related to Gastric Dilatation:

(show top 50) (show all 355)
# Title Authors Year
1
Cell-Free DNA, High-Mobility Group Box-1, and Procalcitonin Concentrations in Dogs With Gastric Dilatation-Volvulus Syndrome. ( 29686994 )
2018
2
A Rare Cause and Complication of Acute Gastric Dilatation: Superior Mesenteric Artery Syndrome and Perforation. ( 29531498 )
2018
3
Acute Massive Gastric Dilatation in a Patient with an Eating Disorder. ( 29491312 )
2018
4
Spontaneous gastric dilatation-volvulus in two cats. ( 29906334 )
2018
5
Acute gastric dilatation in a patient with lupus nephritis: An uncommon presentation of lupus mesenteric vasculitis. ( 29657215 )
2018
6
The canine gut microbiome is associated with higher risk of gastric dilatation-volvulus and high risk genetic variants of the immune system. ( 29889838 )
2018
7
A Prospective Evaluation of a Modified Belt-Loop Gastropexy in 100 Dogs with Gastric Dilatation-Volvulus. ( 30040446 )
2018
8
Gastric dilatation and enterotoxemia in ten captive felids. ( 30211645 )
2018
9
Prognostic value of canine pancreatic lipase immunoreactivity and lipase activity in dogs with gastric dilatation-volvulus. ( 30226861 )
2018
10
Massive gastric dilatation leading to acute respiratory distress 1 year after a Nissen fundoplication. ( 30262534 )
2018
11
Comparison of saphenous and cephalic blood lactate concentrations in dogs with gastric dilatation and volvulus: 45 cases. ( 30363379 )
2018
12
Diagnosis of chronic gastric instability using computed tomography in a Great Dane that progressed to gastric dilatation and volvulus: a literature review and case report. ( 30425956 )
2018
13
Extensive gastric necrosis secondary to acute gastric dilatation: A case report. ( 30448603 )
2018
14
Incidence of gastric dilatation-volvulus following a splenectomy in 238 dogs. ( 29203936 )
2017
15
Differentiating between food bloat and gastric dilatation and volvulus in dogs. ( 29175931 )
2017
16
Modified tube gastropexy using a mushroom-tipped silicone catheter for management of gastric dilatation-volvulus in dogs. ( 28160305 )
2017
17
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5. ( 28738011 )
2017
18
Gastric Dilatation and Abdominal Compartment Syndrome in a Child with Prader-Willi Syndrome. ( 28588153 )
2017
19
Serial evaluation of serum total reduction power potential by cyclic voltammetry in 30 dogs with gastric dilatation and volvulus- a randomised, controlled (lidocaine vs placebo), clinical trial. ( 29202314 )
2017
20
GASTRIC DILATATION VOLVULUS IN ADULT MANED WOLVES (CHRYSOCYON BRACHYURUS). ( 28749303 )
2017
21
Evaluation of echocardiography and cardiac biomarker concentrations in dogs with gastric dilatation volvulus. ( 28960715 )
2017
22
Acute massive gastric dilatation causing ischaemic necrosis and perforation of the stomach. ( 28619737 )
2017
23
Gastric Dilatation Associated with Gastric Colonization with Sarcina-like Bacteria in a Cat with Chronic Enteritis. ( 28892423 )
2017
24
Acute gastric dilatation and ischemia associated with portal vein gas caused by binge eating. ( 29132202 )
2017
25
Acute gastric dilatation due to binge eating may be fatal. ( 28971182 )
2017
26
Acute gastric dilatation after dietary violation. ( 29082742 )
2017
27
Massive gastric dilatation: the radiological picture of eating disorder. ( 27041386 )
2016
28
Unanswered questions on gastric dilatation/volvulus and gastropexy. ( 27980146 )
2016
29
Pyloric localisation in 57 dogs of breeds susceptible to gastric dilatation-volvulus in the UK using computed tomography. ( 27784838 )
2016
30
Unexpected Death Due to Acute Gastric Dilatation and Gastric Necrosis in an 11-Year-Old Boy. ( 27164319 )
2016
31
Binge Eating Leading to Acute Gastric Dilatation, Ischemic Necrosis and Rupture -A Case Report. ( 27134932 )
2016
32
Temporary percutaneous T-fastener gastropexy and continuous decompressive gastrostomy in dogs with experimentally induced gastric dilatation. ( 27347832 )
2016
33
Acute gastric dilatation in a bulimic patient. ( 26975234 )
2016
34
Portal vein gas secondary to acute non-obstructive gastric dilatation. ( 27916447 )
2016
35
Use of a venting PEG tube in the management of recurrent acute gastric dilatation associated with Prader-Willi syndrome. ( 26763981 )
2016
36
Gastric dilatation and intestinal obstruction mimicking acute coronary syndrome with dynamic electrocardiographic changes. ( 27899069 )
2016
37
Dobutamine stress echocardiography resulting in acute gastric dilatation and pneumoporta. ( 27388544 )
2016
38
Rupture of gastrointestinal stromal tumor presenting with sudden onset chest and back pain and accompanied by gastric dilatation. ( 29123817 )
2016
39
Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid. ( 26457032 )
2015
40
C-reactive protein and high mobility group box 1 in dogs with gastric dilatation and volvulus. ( 26088834 )
2015
41
Suspicion of superior mesenteric artery syndrome in a patient with severe gastric dilatation after catheter ablation. ( 25786450 )
2015
42
Acute gastric dilatation in the context of bulimia nervosa. ( 26334471 )
2015
43
Severe gastric dilatation due to superior mesenteric artery syndrome in anorexia nervosa. ( 25639251 )
2015
44
Acute gastric dilatation in the context of bulimia nervosa. ( 26177084 )
2015
45
Delayed Pneumoperitoneum and Acute Pulmonary Edema Secondary to Acute Gastric Dilatation. ( 26668807 )
2015
46
Severe Acute Postoperative Gastric Dilatation. ( 26158257 )
2015
47
Gastrojejunostomy for pyloric stenosis after acute gastric dilatation due to overeating. ( 25663789 )
2015
48
Gastric dilatation volvulus: a retrospective study of 203 dogs with ventral midline gastropexy. ( 26459100 )
2015
49
Young Adult With Abdominal Pain. Gastric dilatation caused by anorexia nervosa. ( 26497441 )
2015
50
Hemostatic variables, plasma lactate concentration, and inflammatory biomarkers in dogs with gastric dilatation-volvulus. ( 26568318 )
2015

Variations for Gastric Dilatation

Expression for Gastric Dilatation

Search GEO for disease gene expression data for Gastric Dilatation.

Pathways for Gastric Dilatation

GO Terms for Gastric Dilatation

Cellular components related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lysosomal lumen GO:0043202 8.62 ARSB MANBA

Molecular functions related to Gastric Dilatation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.46 ARSB ARSH MANBA PNLIP
2 sulfuric ester hydrolase activity GO:0008484 8.96 ARSB ARSH
3 arylsulfatase activity GO:0004065 8.62 ARSB ARSH

Sources for Gastric Dilatation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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