MCID: GST006
MIFTS: 30

Gastric Leiomyoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Leiomyoma

MalaCards integrated aliases for Gastric Leiomyoma:

Name: Gastric Leiomyoma 12 15 70
Leiomyoma of the Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10087
NCIt 50 C3876
SNOMED-CT 67 276812001
UMLS 70 C0238440

Summaries for Gastric Leiomyoma

Disease Ontology : 12 A gastrointestinal system benign neoplasm that is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern.

MalaCards based summary : Gastric Leiomyoma, also known as leiomyoma of the stomach, is related to leiomyoma and intussusception. An important gene associated with Gastric Leiomyoma is ANO1 (Anoctamin 1), and among its related pathways/superpathways are Development Angiotensin activation of ERK and Cardiac Progenitor Differentiation. Affiliated tissues include small intestine, pancreas and smooth muscle.

Related Diseases for Gastric Leiomyoma

Diseases related to Gastric Leiomyoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 leiomyoma 31.3 PDGFRA KIT FH
2 intussusception 30.4 KIT ANO1
3 active peptic ulcer disease 30.2 KIT ANO1
4 bizarre leiomyoma 30.2 FH CALD1
5 leiomyosarcoma 30.1 PDGFRA KIT FH
6 intestinal obstruction 29.8 KIT ANO1
7 leiomyomatosis 29.8 KIT FH
8 hemangiopericytoma, malignant 29.8 KIT CALD1
9 achalasia 29.7 VIPR1 KIT
10 gastrointestinal stromal tumor 29.5 PDGFRA KIT ANO1
11 smooth muscle tumor 29.4 KIT CALD1 ANO1
12 mesenchymal cell neoplasm 29.0 PDGFRA KIT CALD1 ANO1
13 small intestine leiomyosarcoma 10.2 KIT ANO1
14 gastric liposarcoma 10.2 KIT ANO1
15 jejunal neoplasm 10.2 KIT ANO1
16 liver leiomyoma 10.2 KIT ANO1
17 esophageal adenoid cystic carcinoma 10.2 KIT ANO1
18 gastric hemangioma 10.2 KIT ANO1
19 mucinous stomach adenocarcinoma 10.2 KIT ANO1
20 prostate stromal sarcoma 10.2 KIT ANO1
21 small intestine benign neoplasm 10.1 KIT ANO1
22 reticular perineurioma 10.1 PDGFRA KIT
23 laryngeal small cell carcinoma 10.1 PDGFRA KIT
24 pulmonary vein stenosis 10.1 PDGFRA KIT
25 myeloid and lymphoid neoplasms associated with pdgfra rearrangement 10.1 PDGFRA KIT
26 hypereosinophilic syndrome, idiopathic 10.1 PDGFRA KIT
27 sm-ahnmd 10.1 PDGFRA KIT
28 endometrial small cell carcinoma 10.1 PDGFRA KIT
29 holoprosencephaly 3 10.1 VIPR2 VIPR1
30 carney triad 10.1 PDGFRA KIT
31 gliofibroma 10.1 PDGFRA KIT
32 fibrosarcoma of bone 10.0 PDGFRA KIT
33 myelodysplastic/myeloproliferative neoplasm 10.0 PDGFRA KIT
34 plexiform neurofibroma 10.0 PDGFRA KIT
35 chronic eosinophilic leukemia 10.0 PDGFRA KIT
36 large cell neuroendocrine carcinoma 10.0 PDGFRA KIT
37 colon leiomyoma 10.0 KIT FH ANO1
38 desmoid tumor 10.0 PDGFRA KIT
39 volvulus of midgut 10.0
40 adenoma 10.0
41 cavernous hemangioma 10.0 PDGFRA KIT
42 rectum cancer 10.0
43 adenocarcinoma 10.0
44 ovarian cyst 10.0
45 appendicitis 10.0
46 cutaneous leiomyosarcoma 10.0 FH CALD1
47 leiomyoma cutis 10.0 FH CALD1
48 dermis tumor 10.0 FH CALD1
49 aggressive systemic mastocytosis 10.0 PDGFRA KIT
50 systemic mastocytosis 10.0 PDGFRA KIT

Graphical network of the top 20 diseases related to Gastric Leiomyoma:



Diseases related to Gastric Leiomyoma

Symptoms & Phenotypes for Gastric Leiomyoma

Drugs & Therapeutics for Gastric Leiomyoma

Search Clinical Trials , NIH Clinical Center for Gastric Leiomyoma

Genetic Tests for Gastric Leiomyoma

Anatomical Context for Gastric Leiomyoma

MalaCards organs/tissues related to Gastric Leiomyoma:

40
Small Intestine, Pancreas, Smooth Muscle, Colon, Thyroid, Endothelial, Appendix

Publications for Gastric Leiomyoma

Articles related to Gastric Leiomyoma:

(show top 50) (show all 335)
# Title Authors PMID Year
1
Laparoscopic transgastric resection of gastroduodenal intussusception due to gastric leiomyoma. 61
32918440 2020
2
Value of CT Imaging in the Differentiation of Gastric Leiomyoma From Gastric Stromal Tumor. 61
32106696 2020
3
Gastric leiomyoma casusing gastrointestinal bleeding. 61
32963385 2020
4
Gastric leiomyoma in a sea bass Dicentrarchus labrax broodfish. 61
32132274 2020
5
Histopathology Findings in Patients Undergoing Laparoscopic Sleeve Gastrectomy. 61
29305814 2018
6
Ulcerated gastric leiomyoma causing massive upper gastrointestinal bleeding: A case report. 61
29725533 2018
7
Synchronous gastric leiomyoma and intramuscular abdominal wall granular cell tumor with similar imaging features: A case report. 61
29529541 2018
8
Intragastric Single-Incision Laparoscopic Surgery for Gastric Leiomyoma: A Stepwise Approach. 61
28466402 2017
9
Aseptic cerebral venous thrombosis associated with a gastric leiomyoma. 61
29560682 2017
10
Endoscopic dissection of a symptomatic giant gastric leiomyoma arising from the muscularis propria. 61
28355652 2017
11
Partial gastrectomy for resection of a gastric leiomyoma in a guinea pig (Cavia porcellus). 61
27901456 2016
12
Laparoscopic Transgastric Enucleation of a Gastric Leiomyoma near the Esophagogastric Junction and Concomitant Sleeve Gastrectomy: Video Report. 61
26883931 2016
13
Gastric leiomyoma in a child with Gorlin-Goltz syndrome: First pediatric case. 61
26567923 2016
14
¹⁸F-FDG PET/CT and contrast enhanced CT in differential diagnosis between leiomyoma and gastrointestinal stromal tumor. 61
26574696 2015
15
Laparoscopic-Assisted Endoscopic Resection of a Gastric Leiomyoma. 61
25642406 2014
16
Epigenetic alterations in a gastric leiomyoma. 61
25544907 2014
17
The accumulating appreciation of endoscopic submucosal dissection in the treatment of gastrointestinal neoplasms: preliminary experience in local eastern China. 61
23425807 2013
18
The endothelial lipase protein is promising urinary biomarker for diagnosis of gastric cancer. 61
23510199 2013
19
Intragastric endoscopic assisted single incision surgery for gastric leiomyoma of the esophagogastric junction. 61
24416603 2013
20
Gastric leiomyoma and hyperplastic polyposis coli in a patient with multiple cutaneous and uterine leiomyomatosis. 61
22713448 2012
21
Robotic-assisted laparoscopic wedge resection of a gastric leiomyoma with intraoperative ultrasound localization. 61
21919811 2011
22
Endoscopic alcohol injection therapy of giant gastric leiomyomas: an alternative method to surgery. 61
21152456 2010
23
Simultaneous adenocarcinoma and leiomyoma of the stomach presenting as a collision tumor. 61
26192793 2009
24
The role of serum chromogranin A in diarrhoea predominant irritable bowel syndrome. 61
19337629 2009
25
Gastrointestinal bleeding in a pregnant woman: mucinous cystic neoplasm of pancreas mimicking gastrointestinal stromal tumor of stomach. 61
19669687 2009
26
Extracolonic tumors of the gastrointestinal tract detected incidentally at screening CT colonography. 61
17115333 2007
27
Gastric leiomyoma in a free-living Atlantic bottlenosed dolphin (Tursiops truncatus). 61
17259457 2007
28
[Diagnostic image (289). A woman with the sensation that an internal air bubble comes up]. 61
16999277 2006
29
Laparoscopic wedge resection of gastric leiomyoma. 61
17212898 2006
30
Leiomyoma of the gastrointestinal tract with intracytoplasmic inclusion bodies. Report of three cases. 61
16955562 2006
31
Simultaneous laparoscopic treatment for diseases of the gallbladder, stomach, and colon. 61
15956904 2005
32
[Role of MRI in the diagnostic of Gayet Wernicke's encephalopathy (GWE) after gastrectomy and parenteral nutrition]. 61
16190123 2005
33
Gastric leiomyoma. Is there an association with Helicobacter pylori? 61
15573227 2004
34
Application of robotics in general surgery: initial experience. 61
15529850 2004
35
Symptomatic gastric leiomyoma mimicking giant gastric polyp: endoscopic diagnosis and removal. 61
15368793 2004
36
Laparoscopic wedge resection of gastric leiomyoma. 61
14974670 2004
37
Gastric leiomyoma presenting as gastric volvulus. 61
15030039 2003
38
Marked diffuse dilations of the biliary tree associated with intrahepatic calculi, biliary sludges and a mucinous cyst of the pancreatic head in a 99-year-old woman. 61
12895237 2003
39
An unusual abdominal lumpa--a case report. 61
14575225 2003
40
Extraserosal pedunculated leiomyoma of stomach. 61
12416754 2002
41
Digestive hemorrhages of obscure origin. 61
11972222 2002
42
[Treatment of severe anemia and gastrointestinal tract hemorrhage in a Jehovah's Witness]. 61
12587487 2002
43
Laparoscopic wedge resection of a gastric leiomyoma. 61
11443434 2001
44
Laparoscopic intragastric resection of gastric leiomyoma using needlescopic instruments. Case report. 61
11409411 2001
45
Hemoperitoneum secondary to exophytic leiomyoma: report of a case. 61
10819484 2000
46
An undescribed coexistence of a subserosal exophytic gastric leiomyoma with a serous microcystic pancreatic adenoma. 61
10670168 1999
47
Laparoscopic intragastric resection of gastric leiomyoma close to the cardia using a flexible endocutter intraluminally. 61
10636561 1999
48
[Diagnostic possibilities in gastric leiomyoma in relation to two of our cases]. 61
10586620 1999
49
[Gastric leiomyoma. Diagnostic and surgical problems]. 61
10555410 1999
50
Familial desmoids in association with adrenal and ovarian masses and leiomyomas: report of three cases. 61
10215057 1999

Variations for Gastric Leiomyoma

Expression for Gastric Leiomyoma

Search GEO for disease gene expression data for Gastric Leiomyoma.

Pathways for Gastric Leiomyoma

Pathways related to Gastric Leiomyoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.26 PDGFRA KIT CALD1
2 10.98 PDGFRA KIT
3
Show member pathways
10.87 PDGFRA KIT
4
Show member pathways
10.49 PDGFRA KIT
5 10 VIPR2 VIPR1

GO Terms for Gastric Leiomyoma

Cellular components related to Gastric Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.7 VIPR2 VIPR1 PPIP5K1 PDGFRA KIT CALD1
2 receptor complex GO:0043235 9.13 VIPR1 PDGFRA KIT
3 integral component of plasma membrane GO:0005887 9.02 VIPR2 VIPR1 PDGFRA KIT ANO1

Biological processes related to Gastric Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hematopoietic progenitor cell differentiation GO:0002244 9.26 PDGFRA KIT
2 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO:0007188 9.16 VIPR2 VIPR1
3 positive regulation of phosphatidylinositol 3-kinase activity GO:0043552 8.96 PDGFRA KIT
4 positive regulation of phospholipase C activity GO:0010863 8.62 PDGFRA KIT

Molecular functions related to Gastric Leiomyoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.26 PDGFRA KIT
2 G protein-coupled peptide receptor activity GO:0008528 9.16 VIPR2 VIPR1
3 peptide hormone binding GO:0017046 8.96 VIPR2 VIPR1
4 vasoactive intestinal polypeptide receptor activity GO:0004999 8.62 VIPR2 VIPR1

Sources for Gastric Leiomyoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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