Gastric Papillary Adenocarcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Gastric Papillary Adenocarcinoma

MalaCards integrated aliases for Gastric Papillary Adenocarcinoma:

Name: Gastric Papillary Adenocarcinoma ¹² ¹⁵ ⁷³

Papillary Adenocarcinoma of Stomach ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5593

NCIt ⁵⁰ C5472

UMLS ⁷³ C1333785

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Summaries for Gastric Papillary Adenocarcinoma

Disease Ontology : ¹² A papillary adenocarcinoma that is located in the stomach.

MalaCards based summary : Gastric Papillary Adenocarcinoma, also known as papillary adenocarcinoma of stomach, is related to papillary adenocarcinoma and pleomorphic adenoma carcinoma, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Gastric Papillary Adenocarcinoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways/superpathways are MAPK Pathway and DNA Damage Response (only ATM dependent). Affiliated tissues include the stomach, ovary and tonsil.

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Related Diseases for Gastric Papillary Adenocarcinoma

Diseases related to Gastric Papillary Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)

#	Related Disease	Score	Top Affiliating Genes
1	papillary adenocarcinoma	29.9	ERBB2 TP53
2	pleomorphic adenoma carcinoma	10.0	ERBB2 TP53
3	pleomorphic adenoma	10.0	ERBB2 TP53
4	non-proliferative fibrocystic change of the breast	10.0	ERBB2 TP53
5	uterine corpus serous adenocarcinoma	10.0	ERBB2 TP53
6	breast squamous cell carcinoma	10.0	ERBB2 TP53
7	uterine body mixed cancer	10.0	ERBB2 TP53
8	glioma susceptibility 1	10.0	ERBB2 TP53
9	microglandular adenosis	10.0	ERBB2 TP53
10	esophagus adenocarcinoma	10.0	ERBB2 TP53
11	breast benign neoplasm	10.0	ERBB2 TP53
12	thoracic benign neoplasm	10.0	ERBB2 TP53
13	uterine corpus cancer	10.0	ERBB2 TP53
14	mixed cell type cancer	10.0	ERBB2 TP53
15	granulosa cell tumor of the ovary	10.0	ERBB2 TP53
16	hidradenocarcinoma	10.0	ERBB2 TP53
17	primary peritoneal carcinoma	10.0	ERBB2 TP53
18	tonsil cancer	10.0	ERBB2 TP53
19	pre-malignant neoplasm	10.0	ERBB2 TP53
20	fallopian tube carcinoma	10.0	ERBB2 TP53
21	barrett's adenocarcinoma	10.0	ERBB2 TP53
22	ovary adenocarcinoma	10.0	ERBB2 TP53
23	in situ carcinoma	10.0	ERBB2 TP53
24	breast carcinoma in situ	10.0	ERBB2 TP53
25	ovarian cancer 1	10.0	ERBB2 TP53
26	malignant ovarian surface epithelial-stromal neoplasm	10.0	ERBB2 TP53
27	ovary epithelial cancer	10.0	ERBB2 TP53
28	esophageal disease	10.0	ERBB2 TP53
29	female breast cancer	10.0	ERBB2 TP53
30	serous cystadenocarcinoma	10.0	ERBB2 TP53
31	cystadenocarcinoma	10.0	ERBB2 TP53
32	cervical adenocarcinoma	10.0	ERBB2 TP53
33	estrogen-receptor positive breast cancer	10.0	ERBB2 TP53
34	sweat gland cancer	10.0	ERBB2 TP53
35	uterine anomalies	10.0	ERBB2 TP53
36	sporadic breast cancer	10.0	ERBB2 TP53
37	bladder disease	10.0	ERBB2 TP53
38	ductal carcinoma in situ	10.0	ERBB2 TP53
39	carcinosarcoma	10.0	ERBB2 TP53
40	ovarian serous cystadenocarcinoma	10.0	ERBB2 TP53
41	stomach disease	10.0	ERBB2 TP53
42	female reproductive system disease	10.0	ERBB2 TP53
43	reproductive system disease	10.0	ERBB2 TP53
44	gonadal disease	10.0	ERBB2 TP53
45	endometrial adenocarcinoma	10.0	ERBB2 TP53
46	uterine carcinosarcoma	10.0	ERBB2 TP53
47	breast ductal carcinoma	10.0	ERBB2 TP53
48	renal cell carcinoma, papillary, 1	10.0	ERBB2 TP53
49	oral cavity cancer	10.0	ERBB2 TP53
50	endocrine gland cancer	9.9	ERBB2 TP53

Graphical network of the top 20 diseases related to Gastric Papillary Adenocarcinoma:

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Symptoms & Phenotypes for Gastric Papillary Adenocarcinoma

UMLS symptoms related to Gastric Papillary Adenocarcinoma:

abdominal pain, dyspepsia

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Drugs & Therapeutics for Gastric Papillary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Papillary Adenocarcinoma

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Genetic Tests for Gastric Papillary Adenocarcinoma

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Anatomical Context for Gastric Papillary Adenocarcinoma

The Foundational Model of Anatomy Ontology organs/tissues related to Gastric Papillary Adenocarcinoma:

¹⁹

The Stomach

MalaCards organs/tissues related to Gastric Papillary Adenocarcinoma:

⁴¹

Ovary, Tonsil, Pancreas

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Publications for Gastric Papillary Adenocarcinoma

Articles related to Gastric Papillary Adenocarcinoma:

#	Title	Authors	Year
1	Clinicopathological and molecular stability and methylation analyses of gastric papillary adenocarcinoma. ( 28830689 )	Uesugi N....Matsumoto T.	2017

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Genes for Gastric Papillary Adenocarcinoma

Genes related to Gastric Papillary Adenocarcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	19.98	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	TP53	Tumor Protein P53	Protein Coding	16.69	GeneCards inferred via : Publications (show sections)
3	SIL1	SIL1 Nucleotide Exchange Factor	Protein Coding	15.16	DISEASES inferred ¹⁵
4	PCSK9	Proprotein Convertase Subtilisin/Kexin Type 9	Protein Coding	14.88	DISEASES inferred ¹⁵

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Variations for Gastric Papillary Adenocarcinoma

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Expression for Gastric Papillary Adenocarcinoma

Search GEO for disease gene expression data for Gastric Papillary Adenocarcinoma.

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Pathways for Gastric Papillary Adenocarcinoma

Pathways related to Gastric Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	MAPK Pathway ⁷² Show member pathways Toll-like Receptor Pathway ⁷²	11.46	ERBB2 TP53
2	DNA Damage Response (only ATM dependent) ¹	11.38	ERBB2 TP53
3	Bladder cancer ³⁷ ¹	11.12	ERBB2 TP53
4	Platinum drug resistance ³⁷	11.02	ERBB2 TP53
5	Pathways Affected in Adenoid Cystic Carcinoma ¹	10.78	ERBB2 TP53
6	Central carbon metabolism in cancer ³⁷	10.44	ERBB2 TP53

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GO Terms for Gastric Papillary Adenocarcinoma

Molecular functions related to Gastric Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein phosphatase binding	GO:0019903	8.96	ERBB2 TP53
2	protein self-association	GO:0043621	8.62	PCSK9 TP53

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