Gastric Papillary Adenocarcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Gastric Papillary Adenocarcinoma

MalaCards integrated aliases for Gastric Papillary Adenocarcinoma:

Name: Gastric Papillary Adenocarcinoma ¹² ¹⁵ ⁷³

Papillary Adenocarcinoma of Stomach ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:5593

NCIt ⁵⁰ C5472

UMLS ⁷³ C1333785

Sources

Summaries for Gastric Papillary Adenocarcinoma

MalaCards based summary : Gastric Papillary Adenocarcinoma, also known as papillary adenocarcinoma of stomach, is related to papillary adenocarcinoma and gallbladder squamous cell carcinoma, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Gastric Papillary Adenocarcinoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways/superpathways are MAPK Pathway and DNA Damage Response (only ATM dependent).

Sources

Related Diseases for Gastric Papillary Adenocarcinoma

Diseases related to Gastric Papillary Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 60)

#	Related Disease	Score	Top Affiliating Genes
1	papillary adenocarcinoma	29.8	ERBB2 TP53
2	gallbladder squamous cell carcinoma	10.1	ERBB2 TP53
3	uterine corpus serous adenocarcinoma	10.1	ERBB2 TP53
4	non-proliferative fibrocystic change of the breast	10.1	ERBB2 TP53
5	pleomorphic adenoma carcinoma	10.1	ERBB2 TP53
6	fallopian tube adenocarcinoma	10.1	ERBB2 TP53
7	uterine body mixed cancer	10.1	ERBB2 TP53
8	glioma susceptibility 1	10.1	ERBB2 TP53
9	breast squamous cell carcinoma	10.1	ERBB2 TP53
10	oral leukoplakia	10.1	ERBB2 TP53
11	microglandular adenosis	10.1	ERBB2 TP53
12	uterine corpus cancer	10.1	ERBB2 TP53
13	breast benign neoplasm	10.1	ERBB2 TP53
14	thoracic benign neoplasm	10.1	ERBB2 TP53
15	esophagus adenocarcinoma	10.1	ERBB2 TP53
16	mixed cell type cancer	10.1	ERBB2 TP53
17	ovary adenocarcinoma	10.1	ERBB2 TP53
18	granulosa cell tumor of the ovary	10.1	ERBB2 TP53
19	hidradenocarcinoma	10.1	ERBB2 TP53
20	primary peritoneal carcinoma	10.1	ERBB2 TP53
21	pre-malignant neoplasm	10.1	ERBB2 TP53
22	fallopian tube carcinoma	10.1	ERBB2 TP53
23	barrett's adenocarcinoma	10.1	ERBB2 TP53
24	sweat gland cancer	10.1	ERBB2 TP53
25	bladder squamous cell carcinoma	10.1	ERBB2 TP53
26	in situ carcinoma	10.1	ERBB2 TP53
27	ovarian cancer 1	10.1	ERBB2 TP53
28	malignant ovarian surface epithelial-stromal neoplasm	10.1	ERBB2 TP53
29	ovary epithelial cancer	10.0	ERBB2 TP53
30	breast carcinoma in situ	10.0	ERBB2 TP53
31	female breast cancer	10.0	ERBB2 TP53
32	serous cystadenocarcinoma	10.0	ERBB2 TP53
33	cervical adenocarcinoma	10.0	ERBB2 TP53
34	estrogen-receptor positive breast cancer	10.0	ERBB2 TP53
35	cystadenocarcinoma	10.0	ERBB2 TP53
36	endometrial adenocarcinoma	10.0	ERBB2 TP53
37	sporadic breast cancer	10.0	ERBB2 TP53
38	ductal carcinoma in situ	10.0	ERBB2 TP53
39	ovarian serous cystadenocarcinoma	10.0	ERBB2 TP53
40	pleomorphic adenoma	10.0	ERBB2 TP53
41	female reproductive organ cancer	10.0	ERBB2 TP53
42	renal cell carcinoma, papillary, 1	10.0	ERBB2 TP53
43	oral cavity cancer	9.9	ERBB2 TP53
44	breast disease	9.9	ERBB2 TP53
45	uterine carcinosarcoma	9.9	ERBB2 TP53
46	cell type cancer	9.9	ERBB2 TP53
47	breast ductal carcinoma	9.9	ERBB2 TP53
48	transitional cell carcinoma	9.9	ERBB2 TP53
49	pancreas adenocarcinoma	9.8	ERBB2 TP53
50	breast adenocarcinoma	9.8	ERBB2 TP53

Graphical network of the top 20 diseases related to Gastric Papillary Adenocarcinoma:

Sources

Symptoms & Phenotypes for Gastric Papillary Adenocarcinoma

UMLS symptoms related to Gastric Papillary Adenocarcinoma:

abdominal pain, dyspepsia

Sources

Drugs & Therapeutics for Gastric Papillary Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Papillary Adenocarcinoma

Sources

Genetic Tests for Gastric Papillary Adenocarcinoma

Sources

Anatomical Context for Gastric Papillary Adenocarcinoma

Sources

Publications for Gastric Papillary Adenocarcinoma

Articles related to Gastric Papillary Adenocarcinoma:

#	Title	Authors	Year
1	Clinicopathological and molecular stability and methylation analyses of gastric papillary adenocarcinoma. ( 28830689 )	Uesugi N....Matsumoto T.	2017

Sources

Genes for Gastric Papillary Adenocarcinoma

Genes related to Gastric Papillary Adenocarcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ERBB2	Erb-B2 Receptor Tyrosine Kinase 2	Protein Coding	20.21	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	TP53	Tumor Protein P53	Protein Coding	16.78	GeneCards inferred via : Publications (show sections)
3	SIL1	SIL1 Nucleotide Exchange Factor	Protein Coding	15.3	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	PCSK9	Proprotein Convertase Subtilisin/Kexin Type 9	Protein Coding	15.03	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

Sources

Variations for Gastric Papillary Adenocarcinoma

Sources

Expression for Gastric Papillary Adenocarcinoma

Search GEO for disease gene expression data for Gastric Papillary Adenocarcinoma.

Sources

Pathways for Gastric Papillary Adenocarcinoma

Pathways related to Gastric Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	MAPK Pathway ⁷² Show member pathways Toll-like Receptor Pathway ⁷²	11.46	ERBB2 TP53
2	DNA Damage Response (only ATM dependent) ¹	11.38	ERBB2 TP53
3	Bladder cancer ³⁷ ¹	11.12	ERBB2 TP53
4	Platinum drug resistance ³⁷	11.02	ERBB2 TP53
5	Pathways Affected in Adenoid Cystic Carcinoma ¹	10.78	ERBB2 TP53
6	Central carbon metabolism in cancer ³⁷	10.44	ERBB2 TP53

Sources

GO Terms for Gastric Papillary Adenocarcinoma

Biological processes related to Gastric Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of neuron apoptotic process	GO:0043525	8.62	PCSK9 TP53

Molecular functions related to Gastric Papillary Adenocarcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein phosphatase binding	GO:0019903	8.96	ERBB2 TP53
2	protein self-association	GO:0043621	8.62	PCSK9 TP53

Sources

Sources for Gastric Papillary Adenocarcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia