Gastric Squamous Cell Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Gastric Squamous Cell Carcinoma

MalaCards integrated aliases for Gastric Squamous Cell Carcinoma:

Name: Gastric Squamous Cell Carcinoma ¹² ⁵⁹ ¹⁵ ⁷³

Squamous Cell Carcinoma of the Stomach ⁵⁹

Squamous Cell Carcinoma of Stomach ¹²

Characteristics:

Orphanet epidemiological data:

⁵⁹

squamous cell carcinoma of the stomach
Inheritance: Not applicable; Prevalence: 1-5/10000 (Worldwide);

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Neoplasms

Malignant neoplasms of digestive organs

Malignant neoplasm of stomach

Malignant neoplasm: Body of stomach

Malignant neoplasm: Cardia

Malignant neoplasm: Fundus of stomach

Malignant neoplasm: Lesser curvature of stomach, unspecified

Malignant neoplasm: Overlapping lesion of stomach

Malignant neoplasm: Pyloric antrum

Malignant neoplasm: Pylorus

Orphanet: ⁵⁹

Rare gastroenterological diseases

External Ids:

Disease Ontology ¹² DOID:5516

NCIt ⁵⁰ C5475

Orphanet ⁵⁹ ORPHA418959

ICD10 via Orphanet ³⁴ C16.0 C16.1 C16.2 more

UMLS ⁷³ C1333789

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Summaries for Gastric Squamous Cell Carcinoma

MalaCards based summary : Gastric Squamous Cell Carcinoma, also known as squamous cell carcinoma of the stomach, is related to large cell neuroendocrine carcinoma and large cell acanthoma, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Gastric Squamous Cell Carcinoma is DCC (DCC Netrin 1 Receptor), and among its related pathways/superpathways are Pathways in cancer and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Oxaliplatin and Pembrolizumab have been mentioned in the context of this disorder. Affiliated tissues include colon, and related phenotype is craniofacial.

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Related Diseases for Gastric Squamous Cell Carcinoma

Diseases related to Gastric Squamous Cell Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)

#	Related Disease	Score	Top Affiliating Genes
1	large cell neuroendocrine carcinoma	27.6	CHGA ENO2 NCAM1 SYP
2	large cell acanthoma	10.7	KRT10 KRT5
3	epidermolysis bullosa simplex with mottled pigmentation	10.7	KRT10 KRT5
4	breast squamous cell carcinoma	10.7	KRT10 KRT5
5	nodular hidradenoma	10.7	KITLG KRT10
6	malignant biphasic mesothelioma	10.7	KRT10 KRT5
7	epidermolysis bullosa simplex, dowling-meara type	10.7	KRT10 KRT5
8	cutaneous solitary mastocytoma	10.6	KITLG SERPINA3
9	lipoadenoma	10.6	KRT5 SERPINA3
10	pallister-hall syndrome	10.5	GLI1 SHH
11	intraneural perineurioma	10.5	KRT10 KRT5
12	hypothyroidism, thyroidal or athyroidal, with spiky hair and cleft palate	10.5	GLI1 SHH
13	dowling-degos disease 1	10.5	KITLG KRT5
14	keratosis, seborrheic	10.3	KRT10 KRT5
15	cystadenofibroma	10.3	KRT5 NCAM1
16	keratocystic odontogenic tumor	10.3	GLI1 SHH
17	central nervous system tuberculosis	10.3	GLI1 SHH
18	atypical choroid plexus papilloma	10.3	KRT5 SYP
19	squamous cell carcinoma	10.3
20	lung combined type small cell carcinoma	10.2	NCAM1 SYP
21	adenoma of the pancreas	10.2	CHGA SYP
22	peritoneal serous adenocarcinoma	10.2	CHGA SYP
23	cellular ependymoma	10.2	CHGA SYP
24	primary hepatic neuroendocrine carcinoma	10.2	CHGA SYP
25	gastrointestinal neuroendocrine tumor	10.2	CHGA SYP
26	epithelioid leiomyosarcoma	10.2	ENO2 SERPINA3
27	chordoid meningioma	10.2	CHGA SYP
28	hypoganglionosis	10.2	NCAM1 SYP
29	pancreatic endocrine carcinoma	10.2	NCAM1 SYP
30	supratentorial primitive neuroectodermal tumor	10.2	NCAM1 SYP
31	mediastinal cancer	10.2	NCAM1 SYP
32	pulmonary sclerosing hemangioma	10.1	CHGA SYP
33	pancreatoblastoma	10.1	CHGA SYP
34	pulmonary blastoma	10.1	CHGA SYP
35	malignant skin fibrous histiocytoma	10.1	CHGA NCAM1
36	ureter, cancer of	10.1	CHGA SYP
37	tanycytic ependymoma	10.1	CHGA SYP
38	non-functioning pancreatic endocrine tumor	10.1	CHGA SYP
39	cystitis cystica	10.1	KRT5 SYP
40	pleomorphic xanthoastrocytoma	10.1	CHGA SYP
41	malignant dermis tumor	10.1	CHGA NCAM1
42	spermatocele	10.1	NCAM1 SYP
43	granular cell tumor	10.1	ENO2 SERPINA3
44	binswanger's disease	10.1	CHGA SYP
45	lymphoepithelioma-like carcinoma	10.0	ENO2 KRT5
46	basal cell carcinoma	10.0	GLI1 KRT10 SHH
47	multiple mucosal neuroma	10.0	ENO2 NCAM1
48	intracranial primitive neuroectodermal tumor	10.0	CHGA ENO2
49	lung meningioma	10.0	ENO2 NCAM1
50	adrenal rest tumor	10.0	NCAM1 SYP

Graphical network of the top 20 diseases related to Gastric Squamous Cell Carcinoma:

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Symptoms & Phenotypes for Gastric Squamous Cell Carcinoma

UMLS symptoms related to Gastric Squamous Cell Carcinoma:

abdominal pain, dyspepsia

MGI Mouse Phenotypes related to Gastric Squamous Cell Carcinoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	craniofacial	MP:0005382	9.02	GLI1 KITLG KRT5 SHH ENO2

Sources

Drugs & Therapeutics for Gastric Squamous Cell Carcinoma

Drugs for Gastric Squamous Cell Carcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Oxaliplatin

Approved, Investigational

Phase 2

61825-94-3

5310940 9887054 43805 6857599

Synonyms:

CHEMBL1201055

CID9887054

D01790

DACPLAT

Diaminocyclohexane Oxalatoplatinum

Eloxatin

Eloxatin (TN)

Elplat

Foloxatine

L-OHP

Oxalatoplatin

Oxalatoplatinum

oxaliplatin

Oxaliplatin (JAN/USAN/INN)

Oxaliplatin [Usan:Inn:Ban]

oxaliplatine

oxaliplatino

Oxaliplatino [Spanish]

oxaliplatinum

Oxaliplatinum [Latin]

Oxaloplatine [French]

Oxaloplatino [Spanish]

Transplatin

2

Pembrolizumab

Approved

Phase 2

1374853-91-4

3

nivolumab

Approved

Phase 2

946414-94-4

4

leucovorin

Approved, Nutraceutical

Phase 2

58-05-9

143 6006

Synonyms:

(5-formyl-5,6,7,8-tetrahydropteroyl)glutamate

(6R,S)-5-Formyltetrahydrofolate

10-Formyl-7,8-dihydrofolate

10-Formyl-7,8-dihydrofolic acid

5 Formyltetrahydrofolate

5 Formyltetrahydropteroylglutamate

5-Formyl-5,6,7,8-tetrahydrofolate

5-Formyl-5,6,7,8-tetrahydrofolic acid

5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid

5-Formyltetrahydrofolate

5-formyltetrahydrofolic acid

5-Formyltetrahydrofolic acid

5-Formyltetrahydropteroylglutamate

5-Formyltetrahydropteroylglutamic acid

Acid, folinic

Acide folinique

Calcium citrovorum factor

Calcium folinate

Calcium leucovorin

Citrovorum factor

Factor, citrovorum

folinate

Folinate

Folinate, calcium

Folinic acid

Folinic acid calcium salt

Folinic acid calcium salt USP27

Folinic acid SF

Folinic acid-SF

L(-)-5-Formyl-5,6,7,8-tetrahydrofolate

L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid

Leucal

Leucovorin

Leucovorin calcium

Leucovorin folinic acid

Leucovorin, (D)-isomer

Leucovorin, (DL)-isomer

Leucovorin, (R)-isomer

Leucovorin, calcium

Leucovorin, calcium (1:1) salt

Leucovorin, calcium (1:1) salt, (DL)-isomer

Leucovorin, calcium (1:1) salt, pentahydrate

Leucovorin, monosodium salt

Leucovorinum

Leukovorin

Leukovorum

Levoleucovorin

L-leucovorin

L-Leucovorin

L-N-[P-[[(2-amino-5-Formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-glutamic acid

Monosodium salt leucovorin

N(5)-Formyltetrahydrofolate

N-(5-formyl-5,6,7,8-tetrahydropteroyl)-L-glutamic acid

N5-Formyl-5,6,7,8-tetrahydrofolate

N5-Formyl-5,6,7,8-tetrahydrofolic acid

N5-Formyltetrahydrofolate

N5-Formyltetrahydrofolic acid

Rescuvolin

Welcovorin

Wellcovorin

5

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 2

59-30-3

6037

Synonyms:

(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

01769_FLUKA

2d0k

33609-88-0

36653-55-1 (mono-potassium salt)

59-30-3

6484-89-5 (mono-hydrochloride salt)

AC-11682

AC1L1LNX

Acfol (Spain)

Acide folique

Acide folique [INN-French]

Acido folico

Acido folico [INN-Spanish]

Acidum folicum

Acidum folicum [INN-Latin]

Acifolic

AI3-26387

AKOS000503224

Antianemia factor

Apo-Folic

ARONIS014410

b9, Vitamin

BIDD:ER0563

BIDD:GT0641

BIF0608

bmse000299

BPBio1_000654

BSPBio_000594

BSPBio_002338

C00504

C20H20N6O6

CAS-59-30-3

CCRIS 666

CHEBI:27470

CHEMBL1622

CID6037

CPD000471860

Cytofol

D00070

DB00158

DivK1c_000494

Dosfolat b activ

Dosfolat B activ

EINECS 200-419-0

F0043

F7876_SIAL

F7876_SIGMA

F8758_SIGMA

F8798_SIAL

F8890_SIGMA

Facid

Factor U

FOL

Folacid

Folacin

Folaemin

Folaemin [Netherlands]

Folan

Folasic (Australia)

Folate

Folbal

Folcidin

Folcidin (VAN)

Folcysteine

Foldine

Foldine [France]

Folettes

Foliamin

Folic

folic acid

Folic acid

Folic acid (JP15/USP/INN)

Folic acid (TN)

Folic acid [BAN:INN:JAN]

Folic acid [INN:BAN:JAN]

Folic acid dihydrate

Folic acid, (D)-isomer

Folic acid, (DL)-isomer

Folic acid, calcium salt (1:1)

Folic acid, monopotassium salt

Folic acid, monosodium salt

Folic acid, potassium salt

Folic acid, sodium salt

Folicet

Folicet (TN)

Folico

Folico (Italy)

Folina

Folina (Italy)

Folipac

Folsaeure

Folsan

Folsaure

Folsav

Folvite

Folvron

Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L

HMS1921D20

HMS2092N17

HMS501I16

HSDB 2002

IDI1_000494

Incafolic

InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s

KBio1_000494

KBio2_001861

KBio2_004429

KBio2_006997

KBio3_001558

KBioGR_002222

KBioSS_001861

Kyselina listova

Kyselina listova [Czech]

Liver lactobacillus casei factor

Liver Lactobacillus casei factor

LS-2157

Millafol

Mission prenatal

Mittafol

MLS001304016

MLS001335861

MolPort-004-285-551

N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid

N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid

N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamate

N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid

N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-Pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

NCGC00016265-01

NCGC00142391-01

nchembio.108-comp10

Nifolin

Nifolin [Denmark]

NINDS_000494

Novofolacid

Novofolacid [Canada]

N-Pteroyl-L-glutamate

N-Pteroyl-L-glutamic acid

NSC 3073

PGA

PGA (VAN)

Prestwick_230

Prestwick3_000627

PteGlu

Pteroylglutamate

Pteroylglutamic acid

Pteroyl-L-glutamate

Pteroyl-L-glutamic acid

Pteroyl-L-monoglutamate

Pteroyl-L-monoglutamic acid

Pteroylmonoglutamate

Pteroylmonoglutamic acid

SAM002264616

SDCCGMLS-0066738.P001

Serum Folate Level

SMP2_000137

SMR000471860

SPBio_001357

Spectrum_001381

SPECTRUM1502020

Spectrum2_001459

Spectrum3_000749

Spectrum4_001751

Spectrum5_000602

UNII-935E97BOY8

Usaf cb-13

Vitamin B11

Vitamin b9

Vitamin B9

Vitamin Bc

Vitamin BC

Vitamin be

Vitamin Be

Vitamin m

Vitamin M

6

10-deazaaminopterin

Phase 2

7

Folic Acid Antagonists

Phase 2

8

Vitamin B Complex

Phase 2

9

Antibodies

Phase 2

10

Immunoglobulins

Phase 2

11

Antibodies, Monoclonal

Phase 2

12

Folate

Nutraceutical

Phase 2

13

Vitamin B9

Nutraceutical

Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer	Completed	NCT01178944	Phase 2	Oxaliplatin;Pralatrexate
2	Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer	Recruiting	NCT02830594	Phase 2
3	Nivolumab and Ipilimumab in Treating Patients With Rare Tumors	Recruiting	NCT02834013	Phase 2

Search NIH Clinical Center for Gastric Squamous Cell Carcinoma

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Genetic Tests for Gastric Squamous Cell Carcinoma

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Anatomical Context for Gastric Squamous Cell Carcinoma

MalaCards organs/tissues related to Gastric Squamous Cell Carcinoma:

⁴¹

Colon

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Publications for Gastric Squamous Cell Carcinoma

Articles related to Gastric Squamous Cell Carcinoma:

#	Title	Authors	Year
1	Primary Gastric Squamous Cell Carcinoma. ( 29850384 )	Guzman Rojas P....Oharriz J.J.	2018
2	Poorer prognosis in patients with advanced gastric squamous cell carcinoma compared with adenocarcinoma of the stomach: Case report. ( 29390350 )	Meng Y....Zhang S.	2017
3	The clinicopathological features and prognostic factors of gastric squamous cell carcinoma. ( 27559983 )	Dong C....Yuan Y.	2016
4	Clinicopathological Characteristics, Treatment, and Prognosis of 21 Patients with Primary Gastric Squamous Cell Carcinoma. ( 27478431 )	Chen Y....Gou H.	2016
5	Synchronous double cancers of colonic large cell neuroendocrine carcinoma and gastric squamous-cell carcinoma: a case report and review of literature. ( 25197393 )	Xu F....Zhang K.N.	2014
6	Primary gastric squamous cell carcinoma in situ originating from gastric squamous metaplasia. ( 21113875 )	Oono Y....Kaneko K.	2010
7	Gastric squamous cell carcinoma in three llamas. ( 9087939 )	Sartin E.A....Sundberg J.P.	1997
8	Gastric squamous cell carcinoma in three horses. ( 9412445 )	McKenzie E.C....Bolton J.R.	1997
9	Gastric squamous cell carcinoma and fascioliasis in a llama. ( 3402219 )	Cornick J.L.	1988
10	Gastric squamous cell carcinoma in a dog. ( 7361385 )	Patnaik A.K....Lieberman P.H.	1980

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Genes for Gastric Squamous Cell Carcinoma

Genes related to Gastric Squamous Cell Carcinoma (0 elite genes):

(show all 11)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	DCC	DCC Netrin 1 Receptor	Protein Coding	15.77	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	KRT10	Keratin 10	Protein Coding	14.94	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	SERPINA3	Serpin Family A Member 3	Protein Coding	14.48	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	GLI1	GLI Family Zinc Finger 1	Protein Coding	14.44	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	KRT5	Keratin 5	Protein Coding	14.28	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	KITLG	KIT Ligand	Protein Coding	14.26	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	SHH	Sonic Hedgehog	Protein Coding	14.19	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	CHGA	Chromogranin A	Protein Coding	13.98	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	SYP	Synaptophysin	Protein Coding	13.8	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	ENO2	Enolase 2	Protein Coding	13.67	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	13.61	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

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Variations for Gastric Squamous Cell Carcinoma

Cosmic variations for Gastric Squamous Cell Carcinoma:

⁹

(show all 16)

#	Cosmic Mut ID	Gene Symbol	COSMIC Disease Classification (Primary site, Site subtype, Primary histology, Histology subtype)	Mutation CDS	Mutation AA	GRCh38 Location	Conf
1	COSM11123	TP53	stomach,NS,carcinoma,squamous cell carcinoma	c.838A>G	p.R280G	17:7673782-7673782	10
2	COSM6904034	TP53	stomach,NS,carcinoma,squamous cell carcinoma	c.1093C>T	p.H365Y	17:7670616-7670616	10
3	COSM6904040	NOTCH2	stomach,NS,carcinoma,squamous cell carcinoma	c.2898C>G	p.D966E	1:119941609-119941609	10
4	COSM6904039	NOTCH1	stomach,NS,carcinoma,squamous cell carcinoma	c.2055C>G	p.N685K	9:136514662-136514662	10
5	COSM6904037	NOTCH1	stomach,NS,carcinoma,squamous cell carcinoma	c.2213A>G	p.K738R	9:136513532-136513532	10
6	COSM532	KRAS	stomach,NS,carcinoma,squamous cell carcinoma	c.38G>A	p.G13D	12:25245347-25245347	10
7	COSM498	HRAS	stomach,NS,carcinoma,squamous cell carcinoma	c.182A>T	p.Q61L	11:533874-533874	10
8	COSM487	HRAS	stomach,NS,carcinoma,squamous cell carcinoma	c.37G>A	p.G13S	11:534286-534286	10
9	COSM562339		stomach,NS,carcinoma,squamous cell carcinoma	c.838A>G	p.R280G	17:7673782-7673782	10
10	COSM6904038		stomach,NS,carcinoma,squamous cell carcinoma	c.2055C>G	p.N685K	9:136514662-136514662	10
11	COSM99664		stomach,NS,carcinoma,squamous cell carcinoma	c.182A>T	p.Q61L	11:533874-533874	10
12	COSM3448605		stomach,NS,carcinoma,squamous cell carcinoma	c.37G>A	p.G13S	11:534286-534286	10
13	COSM1649339		stomach,NS,carcinoma,squamous cell carcinoma	c.838A>G	p.R280G	17:7673782-7673782	10
14	COSM6904035		stomach,NS,carcinoma,squamous cell carcinoma	c.1093C>T	p.H365Y	17:7670616-7670616	10
15	COSM3378442		stomach,NS,carcinoma,squamous cell carcinoma	c.838A>G	p.R280G	17:7673782-7673782	10
16	COSM6904036		stomach,NS,carcinoma,squamous cell carcinoma	c.2213A>G	p.K738R	9:136513532-136513532	10

Sources

Expression for Gastric Squamous Cell Carcinoma

Search GEO for disease gene expression data for Gastric Squamous Cell Carcinoma.

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Pathways for Gastric Squamous Cell Carcinoma

Pathways related to Gastric Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Pathways in cancer ³⁷	12.18	DCC GLI1 KITLG SHH
2	Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	11.26	KITLG NCAM1 SHH
3	Development_Hedgehog and PTH signaling pathways in bone and cartilage development ²²	10.91	GLI1 SHH
4	Dopaminergic Neurogenesis ¹	10.73	GLI1 SHH
5	Neural Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	10.7	NCAM1 SHH SYP

Sources

GO Terms for Gastric Squamous Cell Carcinoma

Cellular components related to Gastric Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular space	GO:0005615	9.1	CHGA ENO2 KITLG KRT10 SERPINA3 SHH

Biological processes related to Gastric Squamous Cell Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	axon guidance	GO:0007411	9.5	DCC NCAM1 SHH
2	positive regulation of DNA replication	GO:0045740	9.46	GLI1 KITLG
3	neural crest cell migration	GO:0001755	9.43	KITLG SHH
4	extrinsic apoptotic signaling pathway in absence of ligand	GO:0097192	9.4	DCC KITLG
5	positive regulation of smoothened signaling pathway	GO:0045880	9.37	GLI1 SHH
6	prostate gland development	GO:0030850	9.26	GLI1 SHH
7	digestive tract morphogenesis	GO:0048546	9.16	GLI1 SHH
8	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	GO:0021938	8.96	GLI1 SHH
9	ventral midline development	GO:0007418	8.62	GLI1 SHH

Sources

Sources for Gastric Squamous Cell Carcinoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia