MCID: GST017
MIFTS: 31

Gastric Tubular Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Tubular Adenocarcinoma

MalaCards integrated aliases for Gastric Tubular Adenocarcinoma:

Name: Gastric Tubular Adenocarcinoma 12 15 73
Tubular Adenocarcinoma of Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6595
NCIt 50 C5473
UMLS 73 C1333791

Summaries for Gastric Tubular Adenocarcinoma

MalaCards based summary : Gastric Tubular Adenocarcinoma, also known as tubular adenocarcinoma of stomach, is related to tubular adenocarcinoma and gastritis, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Gastric Tubular Adenocarcinoma is MUC2 (Mucin 2, Oligomeric Mucus/Gel-Forming), and among its related pathways/superpathways are CLEC7A (Dectin-1) signaling and O-linked glycosylation. Affiliated tissues include b cells, and related phenotypes are digestive/alimentary and growth/size/body region

Related Diseases for Gastric Tubular Adenocarcinoma

Diseases related to Gastric Tubular Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 193)
# Related Disease Score Top Affiliating Genes
1 tubular adenocarcinoma 30.2 CDX2 CHGA MUC1 MUC2
2 gastritis 29.2 CDX2 CHGA MUC6 PTGS2
3 proliferating trichilemmal cyst 10.7 KRT7 KRT8
4 endolymphatic sac tumor 10.7 KRT7 KRT8
5 hidrocystoma 10.6 KRT7 KRT8
6 appendix adenocarcinoma 10.6 CDX2 KRT7
7 cutaneous adenocystic carcinoma 10.6 KRT7 KRT8
8 cap polyposis 10.6 MUC2 MUC5AC
9 endocervical carcinoma 10.6 KRT7 MUC6
10 glandular cystitis 10.6 CDX2 KRT7
11 chronic cholangitis 10.6 CDX2 MUC2
12 apocrine sweat gland neoplasm 10.6 KRT7 KRT8
13 epithelioid malignant peripheral nerve sheath tumor 10.6 CHGA MUC1
14 microcystic adenoma 10.5 MUC1 MUC6
15 cervical mucinous adenocarcinoma 10.5 KRT7 MAPK1
16 nasal cavity cancer 10.5 KRT7 KRT8
17 epithelial predominant wilms' tumor 10.5 CDX2 KRT7
18 esophageal neuroendocrine tumor 10.5 CHGA SYP
19 ureter small cell carcinoma 10.5 CHGA SYP
20 clear cell meningioma 10.5 CHGA MUC1
21 urinary bladder small cell neuroendocrine carcinoma 10.5 CHGA SYP
22 auditory system cancer 10.5 CHGA SYP
23 adenoma of the pancreas 10.5 CHGA SYP
24 peritoneal serous adenocarcinoma 10.5 CHGA SYP
25 cellular ependymoma 10.5 CHGA SYP
26 gallbladder small cell carcinoma 10.5 CHGA SYP
27 primary hepatic neuroendocrine carcinoma 10.5 CHGA SYP
28 vaginal benign neoplasm 10.5 CDX2 CHGA KRT7
29 vaginal adenoma 10.5 CDX2 CHGA KRT7
30 ovarian mucinous adenocarcinoma 10.5 CDX2 KRT7 MUC2
31 vaginal tubulovillous adenoma 10.5 CDX2 CHGA KRT7
32 gastrointestinal neuroendocrine tumor 10.5 CHGA SYP
33 pancreatic intraductal papillary-mucinous neoplasm 10.4 MUC1 MUC2 MUC6
34 nephrogenic adenofibroma 10.4 CHL1 KRT7 KRT8
35 tumor of exocrine pancreas 10.4 MUC1 MUC2 MUC6
36 thymus adenocarcinoma 10.4 CDX2 KRT7
37 tn polyagglutination syndrome 10.4 MUC1 MUC2 MUC6
38 bronchiolo-alveolar adenocarcinoma 10.4 CDX2 KRT7
39 cecum adenocarcinoma 10.4 CDX2 CHGA KRT7
40 endocervical adenocarcinoma 10.4 CDX2 KRT7 MUC6
41 pulmonary large cell neuroendocrine carcinoma 10.4 CHGA SYP
42 atypical follicular adenoma 10.4 CHGA SYP
43 clear cell adenoma 10.4 MUC2 MUC5AC
44 solid adenocarcinoma with mucin production 10.4 KRT7 MUC1
45 anal gland adenocarcinoma 10.4 KRT7 MUC5AC
46 epstein-barr virus-associated gastric carcinoma 10.4 MUC2 MUC5AC MUC6
47 gastric diffuse adenocarcinoma 10.4 CDX2 KRT7
48 cholecystitis 10.4 MUC1 MUC2 MUC6
49 olfactory nerve neoplasm 10.4 CHGA SYP
50 cauda equina neoplasm 10.4 CHGA SYP

Graphical network of the top 20 diseases related to Gastric Tubular Adenocarcinoma:



Diseases related to Gastric Tubular Adenocarcinoma

Symptoms & Phenotypes for Gastric Tubular Adenocarcinoma

UMLS symptoms related to Gastric Tubular Adenocarcinoma:


abdominal pain, dyspepsia

MGI Mouse Phenotypes related to Gastric Tubular Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.86 KRT8 MAPK1 MUC2 MUC5AC PTGS2 SHH
2 growth/size/body region MP:0005378 9.85 GLI1 KRT8 MAPK1 MBP MUC2 PTGS2
3 neoplasm MP:0002006 9.43 MAPK1 MUC2 PTGS2 SHH CDX2 GLI1
4 reproductive system MP:0005389 9.23 KRT8 MAPK1 MBP PTGS2 SHH CDX2

Drugs & Therapeutics for Gastric Tubular Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Tubular Adenocarcinoma

Genetic Tests for Gastric Tubular Adenocarcinoma

Anatomical Context for Gastric Tubular Adenocarcinoma

MalaCards organs/tissues related to Gastric Tubular Adenocarcinoma:

41
B Cells

Publications for Gastric Tubular Adenocarcinoma

Articles related to Gastric Tubular Adenocarcinoma:

# Title Authors Year
1
Effectiveness of Magnifying Narrow-Band Imaging Endoscopy for Differential Diagnosis between the High-Risk Mixed-Type and Low-Risk Simple-Type of Low-Grade, Well-Differentiated Gastric Tubular Adenocarcinoma. ( 27127502 )
2016
2
Synchronous malignant B-cell lymphoma and gastric tubular adenocarcinoma associated with paraneoplastic cutaneous vasculitis: hypereosinophilic syndrome with mixed cryoglobulinemia is an important sign of paraneoplastic syndrome. ( 21139921 )
2009
3
A unique early gastric tubular adenocarcinoma arising from a pre-existent carcinoid tumor in a patient with a more than 20-year history of type A gastritis: an immunohistochemical and ultrastructural study. ( 12117270 )
2002

Variations for Gastric Tubular Adenocarcinoma

Expression for Gastric Tubular Adenocarcinoma

Search GEO for disease gene expression data for Gastric Tubular Adenocarcinoma.

Pathways for Gastric Tubular Adenocarcinoma

GO Terms for Gastric Tubular Adenocarcinoma

Cellular components related to Gastric Tubular Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 8.92 MUC1 MUC2 MUC5AC MUC6

Biological processes related to Gastric Tubular Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.83 CDX2 GLI1 MAPK1 PTGS2 SHH
2 prostate gland development GO:0030850 9.49 GLI1 SHH
3 digestive tract morphogenesis GO:0048546 9.48 GLI1 SHH
4 maintenance of gastrointestinal epithelium GO:0030277 9.46 MUC2 MUC6
5 negative regulation of blood vessel diameter GO:0097756 9.4 CHGA PTGS2
6 Bergmann glial cell differentiation GO:0060020 9.37 MAPK1 SHH
7 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 9.32 GLI1 SHH
8 maintenance of permeability of blood-brain barrier GO:0035633 9.26 MBP PTGS2
9 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC1 MUC2 MUC5AC MUC6
10 ventral midline development GO:0007418 9.16 GLI1 SHH
11 O-glycan processing GO:0016266 8.92 MUC1 MUC2 MUC5AC MUC6

Sources for Gastric Tubular Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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