MCID: GST017
MIFTS: 34

Gastric Tubular Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Tubular Adenocarcinoma

MalaCards integrated aliases for Gastric Tubular Adenocarcinoma:

Name: Gastric Tubular Adenocarcinoma 12 15 73
Tubular Adenocarcinoma of Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:6595
NCIt 50 C5473
UMLS 73 C1333791

Summaries for Gastric Tubular Adenocarcinoma

MalaCards based summary : Gastric Tubular Adenocarcinoma, also known as tubular adenocarcinoma of stomach, is related to tubular adenocarcinoma and gastritis, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Gastric Tubular Adenocarcinoma is MUC2 (Mucin 2, Oligomeric Mucus/Gel-Forming), and among its related pathways/superpathways are CLEC7A (Dectin-1) signaling and O-linked glycosylation. Affiliated tissues include b cells, lung and ovary, and related phenotypes are digestive/alimentary and growth/size/body region

Related Diseases for Gastric Tubular Adenocarcinoma

Diseases related to Gastric Tubular Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 213)
# Related Disease Score Top Affiliating Genes
1 tubular adenocarcinoma 30.0 CDX2 CHGA MUC1 MUC2 SYP
2 gastritis 29.7 CDX2 CHGA MUC6 PTGS2
3 chronic cholangitis 10.3 CDX2 MUC2
4 endocervical carcinoma 10.3 KRT7 MUC6
5 brooke-spiegler syndrome 10.3 KRT7 KRT8
6 hidrocystoma 10.3 KRT7 KRT8
7 cutaneous adenocystic carcinoma 10.3 KRT7 KRT8
8 adenoid squamous cell carcinoma 10.3 KRT7 KRT8
9 apocrine sweat gland neoplasm 10.3 KRT7 KRT8
10 jejunal adenocarcinoma 10.2 CDX2 KRT7
11 chronic cystitis 10.2 CDX2 KRT7
12 vulva adenocarcinoma 10.2 CDX2 KRT7
13 bladder adenocarcinoma 10.2 CDX2 KRT7
14 thymus adenocarcinoma 10.2 CDX2 KRT7
15 nasal cavity adenocarcinoma 10.2 CDX2 KRT7
16 epithelial predominant wilms' tumor 10.2 CDX2 KRT7
17 clear cell adenoma 10.2 MUC2 MUC5AC
18 gastric diffuse adenocarcinoma 10.2 CDX2 KRT7
19 vaginal benign neoplasm 10.2 CDX2 CHGA
20 clear cell meningioma 10.2 CHGA MUC1
21 microcystic adenoma 10.2 MUC1 MUC6
22 vaginal adenoma 10.2 CDX2 CHGA
23 epithelioid malignant peripheral nerve sheath tumor 10.2 CHGA MUC1
24 cervical mucinous adenocarcinoma 10.2 KRT7 MAPK1
25 vaginal tubulovillous adenoma 10.2 CDX2 CHGA
26 small intestine adenocarcinoma 10.2 MUC2 MUC6
27 adenocarcinoma 10.2
28 gastrointestinal neuroendocrine tumor 10.2 CHGA SYP
29 hepatoid adenocarcinoma 10.2 CDX2 MUC1
30 autonomic nervous system benign neoplasm 10.2 CHGA SYP
31 cervical polyp 10.2 CDX2 MUC6
32 olfactory nerve neoplasm 10.2 CHGA SYP
33 conventional angiosarcoma 10.2 CHGA SYP
34 cauda equina neoplasm 10.2 CHGA SYP
35 nodular ganglioneuroblastoma 10.2 CHGA SYP
36 pulmonary large cell neuroendocrine carcinoma 10.2 CHGA SYP
37 olfactory groove meningioma 10.2 CHGA SYP
38 atypical follicular adenoma 10.2 CHGA SYP
39 pineocytoma 10.2 CHGA SYP
40 proliferating trichilemmal cyst 10.2 KRT7 KRT8
41 endolymphatic sac tumor 10.2 KRT7 KRT8
42 alk-positive anaplastic large cell lymphoma 10.2 MUC1 SHH
43 nodular hidradenoma 10.2 KRT7 MUC1
44 parachordoma 10.2 KRT7 MUC1
45 secretory meningioma 10.2 KRT7 MUC1
46 bile duct adenoma 10.2 KRT7 MUC1
47 monophasic synovial sarcoma 10.2 KRT7 MUC1
48 cap polyposis 10.1 MUC2 MUC5AC
49 appendix adenocarcinoma 10.1 CDX2 KRT7
50 eyelid carcinoma 10.1 KRT7 MUC2

Graphical network of the top 20 diseases related to Gastric Tubular Adenocarcinoma:



Diseases related to Gastric Tubular Adenocarcinoma

Symptoms & Phenotypes for Gastric Tubular Adenocarcinoma

UMLS symptoms related to Gastric Tubular Adenocarcinoma:


abdominal pain, dyspepsia

MGI Mouse Phenotypes related to Gastric Tubular Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.86 CDX2 GLI1 KRT8 MAPK1 MUC2 MUC5AC
2 growth/size/body region MP:0005378 9.85 CDX2 CHGA CHL1 GLI1 KRT8 MAPK1
3 neoplasm MP:0002006 9.43 CDX2 GLI1 MAPK1 MUC2 PTGS2 SHH
4 reproductive system MP:0005389 9.23 CDX2 CHGA GLI1 KRT8 MAPK1 MBP

Drugs & Therapeutics for Gastric Tubular Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Tubular Adenocarcinoma

Genetic Tests for Gastric Tubular Adenocarcinoma

Anatomical Context for Gastric Tubular Adenocarcinoma

MalaCards organs/tissues related to Gastric Tubular Adenocarcinoma:

41
B Cells, Lung, Ovary, Pancreas, Thymus, Small Intestine, Appendix

Publications for Gastric Tubular Adenocarcinoma

Articles related to Gastric Tubular Adenocarcinoma:

# Title Authors Year
1
MicroRNA-21 induces loss of 15-hydroxyprostaglandin dehydrogenase in early gastric tubular adenocarcinoma. ( 30531928 )
2018
2
Effectiveness of Magnifying Narrow-Band Imaging Endoscopy for Differential Diagnosis between the High-Risk Mixed-Type and Low-Risk Simple-Type of Low-Grade, Well-Differentiated Gastric Tubular Adenocarcinoma. ( 27127502 )
2016
3
Synchronous malignant B-cell lymphoma and gastric tubular adenocarcinoma associated with paraneoplastic cutaneous vasculitis: hypereosinophilic syndrome with mixed cryoglobulinemia is an important sign of paraneoplastic syndrome. ( 21139921 )
2009
4
A unique early gastric tubular adenocarcinoma arising from a pre-existent carcinoid tumor in a patient with a more than 20-year history of type A gastritis: an immunohistochemical and ultrastructural study. ( 12117270 )
2002

Variations for Gastric Tubular Adenocarcinoma

Expression for Gastric Tubular Adenocarcinoma

Search GEO for disease gene expression data for Gastric Tubular Adenocarcinoma.

Pathways for Gastric Tubular Adenocarcinoma

GO Terms for Gastric Tubular Adenocarcinoma

Cellular components related to Gastric Tubular Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 8.92 MUC1 MUC2 MUC5AC MUC6

Biological processes related to Gastric Tubular Adenocarcinoma according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.83 CDX2 GLI1 MAPK1 PTGS2 SHH
2 lung morphogenesis GO:0060425 9.51 MAPK1 SHH
3 digestive tract morphogenesis GO:0048546 9.49 GLI1 SHH
4 prostate gland development GO:0030850 9.48 GLI1 SHH
5 maintenance of gastrointestinal epithelium GO:0030277 9.46 MUC2 MUC6
6 negative regulation of blood vessel diameter GO:0097756 9.4 CHGA PTGS2
7 Bergmann glial cell differentiation GO:0060020 9.37 MAPK1 SHH
8 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 9.32 GLI1 SHH
9 ventral midline development GO:0007418 9.26 GLI1 SHH
10 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.26 MUC1 MUC2 MUC5AC MUC6
11 maintenance of permeability of blood-brain barrier GO:0035633 9.16 MBP PTGS2
12 O-glycan processing GO:0016266 8.92 MUC1 MUC2 MUC5AC MUC6

Sources for Gastric Tubular Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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