MCID: GST039
MIFTS: 28

Gastroduodenitis

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastroduodenitis

MalaCards integrated aliases for Gastroduodenitis:

Name: Gastroduodenitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:8644
ICD9CM 35 535.4
ICD10 33 K29.9

Summaries for Gastroduodenitis

MalaCards based summary : Gastroduodenitis is related to gastroduodenal crohn's disease and helicobacter pylori infection, and has symptoms including dyspepsia An important gene associated with Gastroduodenitis is CPN1 (Carboxypeptidase N Subunit 1), and among its related pathways/superpathways are Peptide hormone metabolism and Pertussis. Affiliated tissues include t cells, liver and colon, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Gastroduodenitis

Diseases related to Gastroduodenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 gastroduodenal crohn's disease 12.3
2 helicobacter pylori infection 11.5
3 crohn's disease 10.4
4 intussusception 10.4
5 duodenal ulcer 10.3
6 peptic ulcer disease 10.3
7 gastrointestinal stromal tumor 10.2
8 arthritis 10.2
9 rheumatoid arthritis 10.2
10 colitis 10.2
11 pancreatitis 10.2
12 ulcerative colitis 10.1
13 obstructive jaundice 10.1
14 gastritis 10.1
15 amyloidosis 10.1
16 gastroparesis 10.0
17 familial adenomatous polyposis 10.0
18 gastric ulcer 10.0
19 esophagitis 10.0
20 dyspepsia 10.0
21 adenocarcinoma 10.0
22 peutz-jeghers syndrome 9.9
23 pancreatic cancer 9.9
24 deficiency anemia 9.9
25 osteoarthritis 9.9
26 lymphoma 9.9
27 iron deficiency anemia 9.9
28 peptic esophagitis 9.9
29 iron metabolism disease 9.9
30 acute pancreatitis 9.9
31 gallbladder cancer 9.9
32 lipomatosis 9.9
33 plasmacytoma 9.9
34 adenoma 9.9
35 al amyloidosis 9.9
36 hepatocellular carcinoma 9.8
37 lipomatosis, multiple 9.8
38 gastric cancer 9.8
39 zollinger-ellison syndrome 9.8
40 crohn's colitis 9.8
41 gastric leiomyoma 9.8
42 leiomyoma 9.8
43 angiodysplasia 9.8
44 duodenal obstruction 9.8
45 duodenogastric reflux 9.8
46 alcoholic pancreatitis 9.8
47 gastrinoma 9.8
48 juvenile rheumatoid arthritis 9.8
49 peptic ulcer perforation 9.8
50 peritonitis 9.8

Comorbidity relations with Gastroduodenitis via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Gastroduodenitis:



Diseases related to Gastroduodenitis

Symptoms & Phenotypes for Gastroduodenitis

UMLS symptoms related to Gastroduodenitis:


dyspepsia

GenomeRNAi Phenotypes related to Gastroduodenitis according to GeneCards Suite gene sharing:

26 (show all 12)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.44 LDHA
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-15 9.44 LDHA
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-179 9.44 LDHA
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.44 LDHA
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.44 LDHA
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-203 9.44 CPN1 LDHA
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-212 9.44 LDHA
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.44 CPN1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-38 9.44 LDHA
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-59 9.44 LDHA
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.44 LDHA
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-75 9.44 CPN1

Drugs & Therapeutics for Gastroduodenitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Is a Reporting System for Gastritis or Duodenitis (Modified Lanza Scale) Reproducible? Completed NCT00852150
2 Helicobacter Pylori Infection in Renal Transplant Patients Not yet recruiting NCT03310255

Search NIH Clinical Center for Gastroduodenitis

Genetic Tests for Gastroduodenitis

Anatomical Context for Gastroduodenitis

MalaCards organs/tissues related to Gastroduodenitis:

41
T Cells, Liver, Colon

Publications for Gastroduodenitis

Articles related to Gastroduodenitis:

(show top 50) (show all 54)
# Title Authors Year
1
Acute Gastrointestinal Bleeding in Olmesartan-Associated Collagenous Gastroduodenitis: A Potential Endoscopic Complication. ( 29732226 )
2018
2
Late Relapse of Henoch-Schönlein Purpura in an Adolescent Presenting as Severe Gastroduodenitis. ( 30525016 )
2018
3
Serum Cytokine Signature That Discriminates Helicobacter pylori Positive and Negative Juvenile Gastroduodenitis. ( 28018296 )
2016
4
Collagenous gastroduodenitis with recurrent gastric ulcer in 12-year-old girl. ( 26011716 )
2015
5
Unidentified intralesional and intracellular coccoid microorganism discovered in the young man with a diffuse erosive gastroduodenitis and multiple superficial ulcerations. ( 24495976 )
2014
6
Collagenous gastroduodenitis coexisting repeated Dieulafoy ulcer: A case report and review of collagenous gastritis and gastroduodenitis without colonic involvement. ( 26184019 )
2014
7
Results of drug correction of structural and functional changes in the gingiva in experimental gastroduodenitis. ( 24824716 )
2014
8
Diffuse gastroduodenitis associated with ulcerative colitis: treatment by infliximab. ( 24164601 )
2013
9
Clinical features and treatment of ulcerative colitis-related severe gastroduodenitis and enteritis with massive bleeding after colectomy. ( 24105365 )
2013
10
Diffuse gastroduodenitis and enteritis associated with ulcerative colitis and concomitant cytomegalovirus reactivation after total colectomy: report of a case. ( 22965486 )
2013
11
A case of hemorrhagic gastroduodenitis after proton beam radiation for pancreatic cancer with multiple hemorrhagic risk factors: successful treatment with argon plasma coagulation. ( 26181072 )
2012
12
Collagenous gastroduodenitis. ( 21346601 )
2011
13
Cryptococcal gastroduodenitis: a rare location of the disease. ( 19835991 )
2010
14
Gastroduodenitis and Helicobacter pylori in Nigerians: histopathological assessment of endoscopic biopsies. ( 20037622 )
2009
15
Gastroduodenitis associated with yttrium 90-microsphere selective internal radiation: an iatrogenic complication in need of recognition. ( 18976008 )
2008
16
Chronic ulcerative gastroduodenitis as a first gastrointestinal manifestation of Hermansky-Pudlak syndrome in a 10-year-old child. ( 18473428 )
2008
17
Gastroduodenitis associated with ulcerative colitis. ( 18373161 )
2008
18
A case of acute gastroduodenitis with cytomegalovirus infection in a healthy adult. ( 17827910 )
2007
19
Wild-type and interleukin-10-deficient regulatory T cells reduce effector T-cell-mediated gastroduodenitis in Rag2-/- mice, but only wild-type regulatory T cells suppress Helicobacter pylori gastritis. ( 17353283 )
2007
20
A historical perspective of Helicobacter gastroduodenitis and its complications. ( 17382281 )
2007
21
Diffuse gastroduodenitis and pouchitis associated with ulcerative colitis. ( 17007066 )
2006
22
Clinical quiz: Helicobacter pylori gastroduodenitis. ( 15990645 )
2005
23
Treatment strategies for patients with chronic ischemia of the lower limbs in erosive-ulcerous gastroduodenitis. ( 15097987 )
2004
24
Erosive gastroduodenitis and Helicobacter pylori infection. ( 12824950 )
2003
25
An evaluation of the impact of supplementation with antioxidant vitamins on oxidation stress parameters in children with chronic recurrent gastroduodenitis. ( 11782674 )
2002
26
Severe iron deficiency anemia and asymptomatic nodular gastroduodenitis: an uncommon presentation of Helicobacter pylori infection in a child. ( 11261448 )
2001
27
A model of combined gastroduodenitis and hyperlipidemia in rats. ( 11391412 )
2001
28
Prevalence of gastroduodenitis and Helicobacter pylori infection in a general population sample: relations to symptomatology and life-style. ( 10961710 )
2000
29
Analysis of gastroduodenitis and oesophagitis in relation to dyspeptic/reflux symptoms. ( 9586820 )
1998
30
Helicobacter gastroduodenitis: a serious infectious disease. ( 9167554 )
1997
31
Serum cholinesterase activity in children with gastroduodenitis or peptic ulcer disease. ( 9581484 )
1997
32
Helicobacter gastroduodenitis. Routine treatment will lead to extra workload. ( 9365312 )
1997
33
Aluminum phosphide-induced gastroduodenitis. ( 1397935 )
1992
34
Is gastroduodenitis a cause of chronic dyspepsia? ( 1896828 )
1991
35
Helicobacter pylori, smoking and gastroduodenitis. ( 1797597 )
1991
36
Collagenous gastroduodenitis on collagenous colitis. ( 2209504 )
1990
37
Chloroquine phosphate-induced gastroduodenitis. ( 3234691 )
1988
38
A study of the correlation between endoscopic and histological diagnoses in gastroduodenitis. ( 3300278 )
1987
39
Erosive gastroduodenitis with marked epithelial atypia after hepatic arterial infusion chemotherapy. ( 3923827 )
1985
40
Gastrointestinal occult hemorrhage and gastroduodenitis in cow's milk protein intolerance. ( 6707841 )
1984
41
Celiac artery and superior mesenteric artery insufficiency. Unusual cause of erosive gastroduodenitis. ( 7060896 )
1982
42
Psychological distress in duodenal ulcer and acute gastroduodenitis. A controlled study. ( 7172957 )
1982
43
Gastroduodenitis and peptic ulcer in a rural Liberian community. An endoscopic prospective study. ( 7281215 )
1981
44
Is gastroduodenitis part of the spectrum of peptic ulcer disease? ( 7320465 )
1981
45
Gastroduodenitis. A broader concept of peptic ulcer disease. ( 7418590 )
1980
46
The esophagus in patients with gastroduodenitis and peptic ulcer disease. ( 628876 )
1978
47
Proceedings: High level of fibrinolysis and low factor XIII in erosive haemorrhagic gastroduodenitis. ( 1081747 )
1975
48
Erosive hemorrhagic gastroduodenitis with fibrinolysis and low factor XIII. ( 1081379 )
1975
49
Chronic gastroduodenitis due to laundry bleach. ( 4851026 )
1974
50
Gastroduodenitis as the cause of gastroduodenal ulcer. ( 5352279 )
1969

Variations for Gastroduodenitis

Expression for Gastroduodenitis

Search GEO for disease gene expression data for Gastroduodenitis.

Pathways for Gastroduodenitis

Pathways related to Gastroduodenitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.22 CPN1 GH1
2 10.5 C4A CXCL5

GO Terms for Gastroduodenitis

Cellular components related to Gastroduodenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.26 C4A CPN1 CXCL5 GH1
2 extracellular space GO:0005615 8.92 C4A CPN1 CXCL5 GH1

Biological processes related to Gastroduodenitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of complement activation GO:0030449 8.62 C4A CPN1

Sources for Gastroduodenitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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