MCID: GST045
MIFTS: 59

Gastroenteritis

Categories: Gastrointestinal diseases, Infectious diseases
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Aliases & Classifications for Gastroenteritis

MalaCards integrated aliases for Gastroenteritis:

Name: Gastroenteritis 11 75 53 41 43 14 16 71
Cholera Morbus 11 71
Infectious Colitis, Enteritis and Gastroenteritis 11
Viral Gastroenteritis Due to Rotavirus 33
Enteritis Due to Astrovirus 33
Rotaviral Gastroenteritis 33

Classifications:



External Ids:

Disease Ontology 11 DOID:2326
MeSH 43 D005759
NCIt 49 C34632
SNOMED-CT 68 154278002
ICD10 31 K52.9
UMLS 71 C0017160 C0206151

Summaries for Gastroenteritis

MedlinePlus: 41 Have you ever had the "stomach flu?" What you probably had was gastroenteritis - not a type of flu at all. Gastroenteritis is an inflammation of the lining of the intestines caused by a virus, bacteria, or parasites. Viral gastroenteritis is the second most common illness in the U.S. The cause is often a norovirus infection. It spreads through contaminated food or water or by contact with an infected person. The best prevention is frequent hand washing. Symptoms of gastroenteritis include diarrhea, abdominal pain, vomiting, headache, fever, and chills. Most people recover with no treatment. The most common problem with gastroenteritis is dehydration. This happens if you do not drink enough fluids to replace what you lose through vomiting and diarrhea. Dehydration is most common in babies, young children, older adults, and people with weak immune systems. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary: Gastroenteritis, also known as cholera morbus, is related to eosinophilic gastroenteritis and cryptosporidiosis, and has symptoms including abdominal cramps, abdominal pain and constipation. An important gene associated with Gastroenteritis is ANPEP (Alanyl Aminopeptidase, Membrane), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Fentanyl and Zinc sulfate have been mentioned in the context of this disorder. Affiliated tissues include kidney, breast and small intestine, and related phenotypes are no effect and no effect

Disease Ontology: 11 A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. Chemicals and drugs also cause gastroenteritis. The symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen.

Wikipedia: 75 Gastroenteritis, also known as infectious diarrhea and gastro, is inflammation of the gastrointestinal... more...

Related Diseases for Gastroenteritis

Diseases related to Gastroenteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1286)
# Related Disease Score Top Affiliating Genes
1 eosinophilic gastroenteritis 32.9 RNASE3 IL5 IL4 IL3 CSF2 CCL11
2 cryptosporidiosis 32.4 TNF IFNG CCL11
3 acute diarrhea 32.4 IL10 CXCL8 CRP ALB
4 gastritis 32.3 TNF IL6 IL4 IL1B IL10 CXCL8
5 listeriosis 32.2 TNF IL6 IL4 IL1B IL10
6 dysentery 32.0 TNF IL6 IL1B IL10 CXCL8 CRP
7 crohn's disease 31.9 TNF TLR9 IL6 IL5 IL4 IL1B
8 diarrhea 31.8 TNF IL6 IL5 IL3 IL1B IL10
9 cholera 31.3 TNF IL6 IL5 IL4 IL1B IL10
10 salmonellosis 31.3 TNF TLR9 IL6 IL4 IL1B IL10
11 intussusception 31.2 IL6 CRP ALB
12 typhoid fever 31.2 TNF IL6 IL1B IFNG CRP ALB
13 viral infectious disease 31.1 TNF TLR9 IL6 IL4 IL1B IL10
14 intestinal obstruction 31.1 TNF IL6 CRP ALB
15 hypereosinophilic syndrome 31.1 RNASE3 IL5 IL4 IL3 IL10 IFNG
16 esophagitis, eosinophilic, 1 31.1 RNASE3 IL5 IL4 IL3 CCL11
17 irritable bowel syndrome 31.1 TNF IL6 IL4 IL1B IL10 CXCL8
18 enterocolitis 31.1 TNF IL6 IL10 CXCL8 CRP
19 nutritional deficiency disease 31.0 IL6 CRP ALB
20 neutrophilia, hereditary 31.0 IL6 IL3 CSF2 CRP
21 lactose intolerance 31.0 TNF IL6 IL10 CRP ANPEP ALB
22 giardiasis 31.0 IL6 IL10 ALB
23 spondyloarthropathy 1 30.9 TNF IL6 IL1B IL10 CRP
24 amebiasis 30.9 TNF IL6 IL4 IL1B IL10 CXCL8
25 acute pancreatitis 30.9 TNF IL6 IL1B IL10 CXCL8 CRP
26 ileitis 30.9 TNF IL6 IL10 CSF2
27 esophagitis 30.9 TNF RNASE3 IL6 IL5 IL4 IL1B
28 ige responsiveness, atopic 30.9 RNASE3 IL5 IL4 IL10 IFNG
29 duodenal ulcer 30.8 TNF IL6 IL1B IL10 CXCL8
30 colitis 30.8 TNF TLR9 IL6 IL5 IL4 IL1B
31 peritonitis 30.8 TNF IL6 IL1B IL10 IFNG CXCL8
32 pancreatitis 30.8 TNF IL6 IL1B IL10 CXCL8 CRP
33 iron deficiency anemia 30.8 TNF IL6 CRP
34 paratyphoid fever 30.8 TNF IL1B IFNG CRP
35 food allergy 30.8 TNF RNASE3 IL5 IL4 IL10 IFNG
36 inflammatory bowel disease 1 30.8 TNF IL6 IL1B IL10
37 graft-versus-host disease 30.8 TNF IL10 IFNG
38 chronic rhinitis 30.8 RNASE3 IL5 IL4
39 toxic megacolon 30.7 TNF CRP ALB
40 appendicitis 30.7 TNF IL6 IL1B IL10 IFNG CXCL8
41 intestinal perforation 30.7 TNF IL6 IL10 CRP ALB
42 paralytic ileus 30.7 IL6 CRP ALB
43 vasculitis 30.7 TNF IL6 IL1B IL10 CXCL8 CRP
44 erysipelas 30.6 TNF IL6 IL1B CRP
45 milk allergy 30.6 RNASE3 IL5 IL4 IL10
46 polyarteritis nodosa 30.6 TNF IL6 CRP
47 disseminated intravascular coagulation 30.6 TNF IL6 IL10 CRP
48 disease by infectious agent 30.6 TNF TLR9 LACTB IL6 IL4 IL1B
49 toxic shock syndrome 30.6 TNF IL6 IL4 IL1B IL10 IFNG
50 hepatitis a 30.6 TNF IL4 IL1B IL10 IFNG IFNA1

Graphical network of the top 20 diseases related to Gastroenteritis:



Diseases related to Gastroenteritis

Symptoms & Phenotypes for Gastroenteritis

UMLS symptoms related to Gastroenteritis:


abdominal cramps; abdominal pain; constipation; diarrhea; dyspepsia; fever; heartburn; icterus; nausea and vomiting; pruritus; signs and symptoms, digestive; gastric irritation; gastrointestinal gas

GenomeRNAi Phenotypes related to Gastroenteritis according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 no effect GR00402-S-1 10.18 ALB ANPEP CCL11 CRP CSF2 CXCL8
2 no effect GR00402-S-2 10.18 ALB ANPEP CCL11 CRP CSF2 FUT2

MGI Mouse Phenotypes related to Gastroenteritis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 10.16 ALB ANPEP CCL11 CRP CSF2 FUT2
2 cardiovascular system MP:0005385 10.1 ALB ANPEP CRP CSF2 FUT2 IFNG
3 neoplasm MP:0002006 10.06 ALB CSF2 IFNG IL10 IL1B IL3
4 digestive/alimentary MP:0005381 10.02 ALB FUT2 IFNG IL10 IL4 IL5
5 respiratory system MP:0005388 9.85 CCL11 CSF2 IFNA1 IFNG IL10 IL3
6 skeleton MP:0005390 9.7 CSF2 FUT2 IFNG IL10 IL1B IL3
7 hematopoietic system MP:0005397 9.44 ANPEP CCL11 CSF2 IFNA1 IFNG IL10

Drugs & Therapeutics for Gastroenteritis

Drugs for Gastroenteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 134)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
2
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
3
Zinc cation Approved, Experimental, Investigational Phase 4 7440-66-6, 23713-49-7 32051
4
Metoclopramide Approved, Investigational Phase 4 364-62-5 4168
5
Histamine Approved, Investigational Phase 4 51-45-6 774
6
Dimenhydrinate Approved Phase 4 523-87-5 10660
7
Scopolamine Approved, Investigational Phase 4 51-34-3 153311 3000322
8
Loperamide Approved Phase 4 53179-11-6 3955
9
Ondansetron Approved Phase 4 99614-02-5 4595
10
Bisacodyl Approved Phase 4 603-50-9 2391
11
Ascorbic acid Approved, Nutraceutical Phase 4 50-81-7 54676860 54670067 5785
12
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 2052-63-3, 22737-97-9, 22737-96-8, 68-26-8 9904001 9947823 5280382 445354
13
Racecadotril Investigational Phase 4 81110-73-8 107751
14 Analgesics Phase 4
15 Emetics Phase 4
16
Histamine phosphate Phase 4 51-74-1 134614
17 Histamine H1 Antagonists Phase 4
18 Histamine Antagonists Phase 4
19 Butylscopolammonium Bromide Phase 4
20 Mydriatics Phase 4
21 Muscarinic Antagonists Phase 4
22 Parasympatholytics Phase 4
23 Cholinergic Antagonists Phase 4
24 Cholinergic Agents Phase 4
25 Anesthetics Phase 4
26 Bromides Phase 4
27 Antidiarrheals Phase 4
28
protease inhibitors Phase 4
29 HIV Protease Inhibitors Phase 4
30 Dermatologic Agents Phase 4
31 Gastrointestinal Agents Phase 4
32 Antiemetics Phase 4
33 Psychotropic Drugs Phase 4
34 Antipsychotic Agents Phase 4
35 Neurotransmitter Agents Phase 4
36 Anti-Anxiety Agents Phase 4
37 Micronutrients Phase 4
38 Protective Agents Phase 4
39 Vitamins Phase 4
40 Trace Elements Phase 4
41 Antioxidants Phase 4
42 Retinol palmitate Phase 4
43 Pharmaceutical Solutions Phase 4
44 Plasma-lyte 148 Phase 4
45 Ophthalmic Solutions Phase 4
46
Serotonin Investigational, Nutraceutical Phase 4 50-67-9 5202
47
Sodium citrate Approved, Investigational Phase 3 68-04-2 23431961
48
Echinacea Approved, Experimental Phase 3
49
Benralizumab Approved, Investigational Phase 3 1044511-01-4
50
Dopamine Approved Phase 3 62-31-7, 51-61-6 681

Interventional clinical trials:

(show top 50) (show all 226)
# Name Status NCT ID Phase Drugs
1 The ORVAC Trial: A Phase IV, Double-blind, Randomised, Placebo-controlled Clinical Trial of a Third Scheduled Dose of RV1 Rotavirus Vaccine in Australian Indigenous Infants to Improve Protection Against Gastroenteritis Unknown status NCT02941107 Phase 4 Rotarix (RV1);Placebo
2 Assessment of Analgesic Efficacy and Safety of Intravenous Hyoscine-N-Butylbromide in Patients With Abdominal Colic Associated With Acute Gastroenteritis; a Randomized, Double-blind, Placebo Controlled Study Unknown status NCT02508142 Phase 4 Hyoscine-N-Butylbromide
3 Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis: Randomized, Double-Blind Controlled Trial Completed NCT01467570 Phase 4
4 Efficacy and Safety of Probiotics in the Treatment of Acute Gastroenteritis in Children Completed NCT03539913 Phase 4
5 Impact of Systematic Infants Vaccination Against Rotavirus on Gastroenteritis Hospitalization: a Prospective Study in Brest District, France. Completed NCT00740935 Phase 4
6 Ondansetron Vs Metoclopramide in the Treatment of Vomiting in Gastroenteritis Patients: A Randomized Controlled Trial Completed NCT01165866 Phase 4 Treatment 1. Metoclopramide;Treatment 2 Ondansetron
7 Rapid Diagnostics and Probiotic Therapy for Paediatric Acute Gastroenteritis - a Randomized, Factorial, Controlled, Placebo-controlled, Pilot Trial Completed NCT02025452 Phase 4
8 Comparison of Clinical Efficacy of Enteroadsorbent Polymethylsiloxane vs Probiotic Lactobacillus Reuteri in the Treatment of Rotaviral Gastroenteritis in Infants and Toddlers. Completed NCT04116307 Phase 4
9 Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis: A Randomized Controlled Trial Completed NCT00392145 Phase 4 Standard IV rehydration;Rapid intravenous rehydration (RIVR)
10 A Randomized Double-blind Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Moderate Vomiting Due to Acute Gastroenteritis Completed NCT00124787 Phase 4 Dimenhydrinate;Placebo
11 Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide: Randomized Double Blind Placebo Controlled Trial Completed NCT04682860 Phase 4 Hyoscine N Butylbromide
12 Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in Emergency Departments in Pakistan Completed NCT01870648 Phase 4 Ondansetron;Placebo
13 Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in Emergency Departments in Pakistan Completed NCT01870635 Phase 4 Ondansetron;Placebo
14 Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis: A Double Blind Randomized, Placebo- Controlled Trial Completed NCT01657032 Phase 4
15 Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Under Six Months. Completed NCT01571856 Phase 4 Zinc Sulfate
16 The Treatment Effect of Bio-Three on Children With Enteritis Due to Salmonella or Rotavirus or Any Unknown Reason Completed NCT01480947 Phase 4 Bio-three
17 Introduction of an Oral Live Human Rotavirus (Rotarix) Vaccine in Matlab Completed NCT00737503 Phase 4
18 Impact of Four Patient Information Leaflets (PIL) on Patient Behaviour : a Randomised Controlled Trial in Primary Care. Completed NCT01398696 Phase 4
19 Immunogenicity of the Human Rotavirus Vaccine (Rotarix™) at Varying Schedules, Doses, and Ages in Rural Ghana Completed NCT01575197 Phase 4
20 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children: A Randomized Double-blind Trial Completed NCT01564290 Phase 4 Placebo probiotic
21 An Open-label, Pilot Study to Compare the Safety and Immunogenicity of an Alternate Dosing Schedule (2-5 Weeks, 2 Months, and 4 Months) for Pentavalent Rotavirus Vaccine (RotaTeq) to the Standard Recommended Schedule (2, 4, and 6 Months) Completed NCT01960725 Phase 4
22 Efficacy of Racecadotril in the Management of Acute Watery Diarrhea in Children Completed NCT01577043 Phase 4 Racecadotril
23 The Immunogenicity of Rotavirus Vaccine Under Different Age Schedules and the Impact of Withholding Breast Feeding Around the Time of Vaccination on the Immunogenicity of Rotarix Vaccine Completed NCT01199874 Phase 4
24 Bacillus Clausii in the Treatment of Acute Community-acquired Diarrhea Among Latin American Children (cadiLAc) Completed NCT02169817 Phase 4 Bacillus clausii;Oral Rehydration Therapy
25 The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children- a Randomized, Placebo-controlled, Double-blind Trial Recruiting NCT03988257 Phase 4
26 Examining the Effect of Ondansetron on Bowel Prep Success Recruiting NCT05439772 Phase 4 Ondansetron
27 A Double-Blind, Randomized, Comparative Efficacy and Safety Trial of Intravenous Solutions for the Treatment of Moderate to Severe Dehydration in Children With Acute Gastroenteritis Terminated NCT01234883 Phase 4 multiple electrolyte solution;saline
28 Comparison of Efficacy of Ondansetron Versus Metoclopramide for Vomiting in Children With Acute Gastroenteritis: Randomized Controlled Clinical Trial Unknown status NCT02619201 Phase 3 Ondansetron;metoclopramide
29 Phase II Double Blind Placebo-controled Randomized Comparative Multicentered Study of Efficacy and Safety of Filtrum-STI, 0,4g Tablets (Produced by AVVA RUS) in Children With Viral Gastroenteritis Unknown status NCT01113346 Phase 2, Phase 3 Filtrum-STI (lignin hydrolytic);Placebo
30 A Randomised, Placebo-controlled Trial of Oral Nitazoxanide for the Empiric Treatment of Acute Gastroenteritis Among Australian Indigenous Children Unknown status NCT02165813 Phase 2, Phase 3 Nitazoxanide;placebo
31 A Phase III, Randomized, Double Blind, Placebo Controlled Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E, Against Severe Rotavirus Gastroenteritis in Infants Unknown status NCT01305109 Phase 3
32 Oral Ondansetron vs Domperidone for Symptomatic Treatment of Vomiting During Acute Gastroenteritis in Children: Multicentre Randomized Controlled Trial Completed NCT01257672 Phase 3 Ondansetron;Domperidone;placebo
33 Phase III, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Live Attenuated Bovine-Human Rotavirus Reassortant Pentavalent Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Healthy Indian Infants Completed NCT02133690 Phase 3
34 Community Based Prophylaxis for Rotavirus Gastroenteritis in Children by an Anti-rotavirus Protein Based Food Supplement Completed NCT01265355 Phase 2, Phase 3
35 Randomized, Placebo-Controlled, Phase 3 Trial of BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis (The GUARD Study) Completed NCT02246439 Phase 3 RHB-102;Placebo Oral Tablet
36 Randomized, Double-blind, Placebo-controlled Phase III Clinical Trial to Assess the Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis Among Infants in Niger Completed NCT02145000 Phase 3
37 Gelatin Tannate as Treatment for Acute Childhood Gastroenteritis: a Prospective, Randomized, Single-blind Controlled Clinical Trial Completed NCT02644200 Phase 3
38 the Effectiveness of Echinacea, Propolis and Vitamin C in the Prevention of Respiratory Tract Infections and Gastroenteritis in Preschool Age Children: a Prospective Study Completed NCT00231218 Phase 3 dietary supplement--echinacea, propolis, and vitamin c
39 A Multicenter, Double-Blind, Randomized Study to Compare The Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00392574 Phase 3 Prulifloxacin;Placebo
40 The Implementation of a Gastroenteritis Education Program Completed NCT00311831 Phase 3
41 A Multicenter, Double-Blind, Randomized Study to Compare the Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00448422 Phase 3 prulifloxacin
42 Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis: Randomized Controlled Trial Completed NCT01853124 Phase 3 Placebo;Lacidofil
43 Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis Completed NCT01773967 Phase 2, Phase 3 LGG;micro-crystalline cellulose
44 A Randomized, Double-Blind, Placebo-controlled Clinical Trial to Evaluate the Efficacy of Benralizumab (Anti-IL5RA) in Subjects With Eosinophilic Gastritis Completed NCT03473977 Phase 2, Phase 3
45 A Seamless, Sequential Phase III, Randomized, Multi Center Single Blind Study to Evaluate Immunogenicity, Safety, Reactogenicity of Liquid ROTAVAC 5C Vaccine as a 3-dose Series When Compared With ROTAVAC® in Infants Completed NCT04819412 Phase 3
46 A Phase III Randomized, Placebo-controlled Clinical Trial to Study the Efficacy and Safety of V260 in Healthy Infants in Japan Completed NCT00718237 Phase 3
47 A Phase II/III, Multicenter, Open-Label, Randomized Study of Liquid Bovine Rotavirus Pentavalent Vaccine (LBRV-PV) to Evaluate Lot-to-Lot Consistency and to Compare Non-Inferiority With ROTASIIL (Lyophilized BRV-PV) in Healthy Infants in India Completed NCT03474055 Phase 2, Phase 3
48 A Phase III, Multicenter, Open Label, Randomized Study of Bovine Rotavirus Pentavalent Vaccine (BRV-PV) to Evaluate Lot-To-Lot Consistency and to Investigate Potential Interference With Routine UIP Vaccinations in Healthy Infants in India. Completed NCT02584816 Phase 3
49 A Phase 3 Randomized, Open-Label, Clinical Trial to Study the Immunogenicity and Safety of Concomitant and Non-Concomitant Administration of V260 and Inactivated Poliomyelitis Vaccine (IPV) in Chinese Healthy Infants Completed NCT04481191 Phase 3
50 A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy, Safety, and Immunogenicity of V260 in Healthy Chinese Infants Completed NCT02062385 Phase 3

Search NIH Clinical Center for Gastroenteritis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


ERYTHROMYCIN PWDR

Cochrane evidence based reviews: gastroenteritis

Genetic Tests for Gastroenteritis

Anatomical Context for Gastroenteritis

Organs/tissues related to Gastroenteritis:

MalaCards : Kidney, Breast, Small Intestine, Bone Marrow, Liver, Brain, T Cells

Publications for Gastroenteritis

Articles related to Gastroenteritis:

(show top 50) (show all 21529)
# Title Authors PMID Year
1
Multiplex PCR: Aid to more-timely and directed therapeutic intervention for patients with infectious gastroenteritis. 62 41
36254068 2022
2
Epidemiology of Human Adenovirus in Pakistani Children Hospitalized with Community-Acquired Gastroenteritis under the Age of Five Years. 62 41
36231834 2022
3
Association between breastfeeding, host genetic factors, and calicivirus gastroenteritis in a Nicaraguan birth cohort. 62 41
36240197 2022
4
[Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus]. 53 62
19634766 2009
5
Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus. 53 62
17467767 2007
6
Nosocomial outbreak of pediatric gastroenteritis caused by CTX-M-14-type extended-spectrum beta-lactamase-producing strains of Salmonella enterica serovar London. 53 62
16000495 2005
7
Identification of a putative cellular receptor 150 kDa polypeptide for porcine epidemic diarrhea virus in porcine enterocytes. 53 62
14685034 2003
8
[A study of serum mitochondrial enzymes(mCK, mAST, mMDH) in rotavirus and adenovirus gastroenteritis in pediatric patients]. 53 62
11769565 2001
9
Interspecies aminopeptidase-N chimeras reveal species-specific receptor recognition by canine coronavirus, feline infectious peritonitis virus, and transmissible gastroenteritis virus. 53 62
8985407 1997
10
Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct from the enzymatic site. 53 62
7913510 1994
11
Rapid and specific detection of the thermostable direct haemolysin gene in Vibrio parahaemolyticus by the polymerase chain reaction. 53 62
8126441 1993
12
Biochemical and immunologic characterization of serum biotinidase in partial biotinidase deficiency. 53 62
1561012 1992
13
Inactivation of two SARS-CoV-2 virus surrogates by electron beam irradiation on large yellow croaker slices and their packaging surfaces. 62
36091572 2023
14
Swine coronaviruses (SCoVs) and their emerging threats to swine population, inter-species transmission, exploring the susceptibility of pigs for SARS-CoV-2 and zoonotic concerns. 62
35584308 2022
15
Rotavirus genotypes and clinical outcome of natural infection based on vaccination status in the post-vaccine era. 62
35240934 2022
16
Systematic review of the effect of additional doses of oral rotavirus vaccine on immunogenicity and reduction in diarrhoeal disease among young children. 62
36247922 2022
17
Differential expression of long non-coding RNAs under Peste des petits ruminants virus (PPRV) infection in goats. 62
35129076 2022
18
Epidemiology of Norovirus in the First 2 Years of Life in an Australian Community-based Birth Cohort. 62
36223234 2022
19
Clinical characteristics, health care resource utilization and direct medical costs of Rotavirus hospitalizations in Spain (2013-2018). 62
35435807 2022
20
The anti-campylobacter activity of eugenol and its potential for poultry meat safety: A review. 62
35749879 2022
21
Ecological effects, remediation, distribution, and sensing techniques of chromium. 62
35932914 2022
22
Campylobacter biofilms. 62
35963043 2022
23
Improvement of nested reverse transcription-polymerase chain reaction (RT-PCR) with high specificity and sensitivity detection of sapovirus in food matrix. 62
36028003 2022
24
Co-culture with Acinetobacter johnsonii enhances benzalkonium chloride resistance in Salmonella enterica via triggering lipid A modifications. 62
36095868 2022
25
Poliovirus returns to the UK after nearly 40 years: current efforts and future recommendations. 62
36126982 2022
26
Association of histo-blood group antigens and predisposition to gastrointestinal diseases. 62
35882942 2022
27
Exclusive circulation of canine parvovirus type 2c in the Guadalajara metropolitan area in western Mexico: a five-year study. 62
35794491 2022
28
Burden of rotavirus gastroenteritis on caregivers: Findings from a systematic literature review. 62
35377826 2022
29
Trends in pediatric ambulatory community acquired infections before and during COVID-19 pandemic: A prospective multicentric surveillance study in France. 62
36034052 2022
30
Association between early childhood lower respiratory tract infections and subsequent asthma. 62
34706607 2022
31
Smell and Taste Dysfunction in Pediatric Patients With SARS-CoV-2 Infection. 62
36084419 2022
32
A systematic review: Botany, phytochemistry, traditional uses, pharmacology, toxicology, quality control and pharmacokinetics of Ilex rotunda Thunb. 62
35781006 2022
33
Gastrointestinal symptoms and endoscopy findings after pediatric solid organ transplantation: A case series. 62
35950902 2022
34
Investigation of the use of multiplex PCR in childhood diarrhea with clinical and epidemiological features. 62
36272732 2022
35
Chronic Diarrhea Associated with Edwardsiella Tarda Gastroenteritis: A Case Report and Literature Review. 62
35895886 2022
36
Visual and Rapid Detection of Porcine Epidemic Diarrhea Virus (PEDV) Using Reverse Transcription Loop-Mediated Isothermal Amplification Method. 62
36230453 2022
37
Outbreak of sexually transmitted, extensively drug-resistant Shigella sonnei in the UK, 2021-22: a descriptive epidemiological study. 62
35809593 2022
38
A Comparative Study of Febrile Seizures and Febrile Convulsions Associated With Mild Gastroenteritis. 62
35933805 2022
39
Update on benign convulsions with mild gastroenteritis. 62
34961297 2022
40
Rotavirus immunisation status affects the efficacy of Lacticaseibacillus rhamnosus GG for the treatment of children with acute diarrhoea: a meta-analysis. 62
36004717 2022
41
The temporal pattern and relationship of Campylobacter prevalence in broiler slaughter batches and human campylobacteriosis cases in Sweden 2009-2019. 62
35792470 2022
42
Efficacy, safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants. 62
35926726 2022
43
Acute care diagnostics in children for general radiologists - not alone in the hospital at night. 62
36261070 2022
44
Cryptosporidiosis in Finland is predominantly of domestic origin: investigation of increased reporting, 1995-2020. 62
36266958 2022
45
Probiotics for the management of pediatric gastrointestinal disorders: position paper of the ESPGHAN Special Interest Group on Gut Microbiota and Modifications. 62
36219218 2022
46
Characterization of Escherichia coli O157:non-H7 isolated from retail food in China and first report of mcr-1/IncI2-carrying colistin-resistant E. coli O157:H26 and E. coli O157:H4. 62
35777301 2022
47
Management and Outcomes of Salmonella Gastroenteritis in the Era of Rapid Molecular Testing. 62
36263712 2022
48
Establishment of a recombinase polymerase amplification (RPA) fluorescence assay for the detection of swine acute diarrhea syndrome coronavirus (SADS-CoV). 62
36221092 2022
49
Rotavirus meningitis in an adult with transient aphasia. 62
35811079 2022
50
Climate variability and change are drivers of salmonellosis in Australia: 1991 to 2019. 62
35764154 2022

Variations for Gastroenteritis

Expression for Gastroenteritis

Search GEO for disease gene expression data for Gastroenteritis.

Pathways for Gastroenteritis

Pathways related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 72)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.02 ANPEP CCL11 CRP CSF2 CXCL8 IFNA1
2
Show member pathways
13.89 CCL11 CSF2 CXCL8 IL10 IL1B IL3
3
Show member pathways
13.74 CCL11 CSF2 CXCL8 IFNA1 IFNG IL10
4
Show member pathways
13.64 CCL11 CXCL8 IFNA1 IFNG IL10 IL1B
5
Show member pathways
13.52 TNF TLR9 IL6 IL5 IL4 IL3
6
Show member pathways
13.42 TNF IL6 IL5 IL4 IL3 IL1B
7
Show member pathways
13.38 CCL11 CSF2 CXCL8 IFNA1 IFNG IL10
8
Show member pathways
12.93 TNF TLR9 IL6 IL1B IFNA1 CXCL8
9
Show member pathways
12.75 TNF TLR9 IL6 IL3 IL1B
10 12.72 TNF TLR9 IL4 IL3 IL1B IL10
11
Show member pathways
12.71 TNF IL6 IL5 IL4 IL3 IL1B
12
Show member pathways
12.68 TNF TLR9 IL6 IL1B CXCL8
13
Show member pathways
12.66 TNF IL6 IL1B IL10 IFNG
14
Show member pathways
12.66 CXCL8 IFNA1 IL1B IL6 TLR9 TNF
15
Show member pathways
12.55 TNF TLR9 IL6 IL4 IL1B IFNG
16
Show member pathways
12.41 TNF IL6 IL1B IFNG CXCL8
17
Show member pathways
12.33 TNF IL6 CXCL8 CSF2
18
Show member pathways
12.32 CSF2 IFNG IL3 IL4 TNF
19
Show member pathways
12.3 TNF IL5 IL4 IL10 IFNG CSF2
20 12.29 TNF IL6 IL1B IL10 CXCL8
21 12.26 IFNG IL10 IL1B IL4 IL6 TNF
22 12.25 TNF TLR9 IL6 IFNG
23 12.15 CXCL8 IFNG IL1B IL4 IL6 TNF
24 12.09 IL6 IL3 IL1B IFNG CXCL8
25
Show member pathways
12.09 TNF TLR9 IL6 IL1B IL10 IFNG
26 12.05 TNF IL6 IL4 IL1B IL10 CXCL8
27
Show member pathways
12.02 TLR9 IL6 IL4 IL1B IFNG
28 11.98 TNF IL5 IL4 IL1B IL10 IFNG
29 11.96 CSF2 CXCL8 IFNG IL4 IL5 IL6
30 11.95 TNF IL5 IL4 IL1B IL10 IFNG
31 11.9 TNF IL6 IL4 IL10 IFNG CRP
32 11.89 TNF IL6 IL1B CXCL8
33 11.85 IL6 IL4 IL1B IFNG
34
Show member pathways
11.83 TNF IL1B IFNG
35
Show member pathways
11.83 TNF IL6 IL1B IFNG CXCL8 CSF2
36
Show member pathways
11.81 IL6 CXCL8 CRP
37 11.8 TNF IL6 IL10 CXCL8
38 11.8 TNF IL6 IL1B IL10
39 11.79 IL6 IL10 IFNG
40 11.78 IL5 IL4 IL10 CCL11
41
Show member pathways
11.78 TNF IL6 IL5 IL4 IL10 IFNG
42 11.78 TNF TLR9 IL6 IL1B IL10 IFNG
43
Show member pathways
11.76 IL5 IL3 CSF2
44 11.7 TNF IL10 CXCL8 CSF2
45 11.7 TNF IL6 IFNG CXCL8
46 11.7 IL6 IL5 IL4 IL10 IFNG CXCL8
47 11.69 IL5 IL4 IL10 IFNG CCL11
48 11.67 IL6 IFNG CXCL8
49 11.67 TNF IL6 IL5 IL4 IL3 IL10
50 11.64 TNF IL6 IL1B IFNG

GO Terms for Gastroenteritis

Cellular components related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 10.16 ALB CCL11 CRP CSF2 CXCL8 IFNA1
2 extracellular space GO:0005615 9.83 ALB ANPEP CCL11 CRP CSF2 CXCL8

Biological processes related to Gastroenteritis according to GeneCards Suite gene sharing:

(show all 44)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.5 ANPEP CCL11 CXCL8 IFNG IL10 IL1B
2 positive regulation of cell population proliferation GO:0008284 10.46 IL6 IL5 IL4 IL3 IL1B IFNG
3 defense response to Gram-positive bacterium GO:0050830 10.3 CRP IL1B IL6 RNASE3 TNF
4 positive regulation of DNA-binding transcription factor activity GO:0051091 10.29 TNF IL6 IL5 IL1B IL10
5 inflammatory response GO:0006954 10.28 CCL11 CRP CXCL8 IL1B IL5 IL6
6 positive regulation of gene expression GO:0010628 10.28 CRP CSF2 CXCL8 IFNG IL1B IL4
7 positive regulation of inflammatory response GO:0050729 10.27 TNF TLR9 IL1B IFNG
8 positive regulation of interleukin-8 production GO:0032757 10.24 TNF TLR9 IL6 IL1B
9 positive regulation of interleukin-6 production GO:0032755 10.24 TNF TLR9 IL6 IL1B IFNG
10 humoral immune response GO:0006959 10.23 IFNA1 IFNG IL6 TNF
11 response to virus GO:0009615 10.22 TNF TLR9 IFNG CCL11
12 regulation of insulin secretion GO:0050796 10.19 TNF IL6 IL1B IFNG
13 positive regulation of nitric oxide biosynthetic process GO:0045429 10.16 TNF IL1B IFNG
14 positive regulation of interleukin-10 production GO:0032733 10.16 TLR9 IL6 IL4
15 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 10.15 TNF IL1B CSF2
16 liver regeneration GO:0097421 10.14 TNF IL6 IL10
17 positive regulation of receptor signaling pathway via JAK-STAT GO:0046427 10.13 TNF IL6 IL5 IL10
18 positive regulation of glial cell proliferation GO:0060252 10.12 IL1B IL6 TNF
19 positive regulation of membrane protein ectodomain proteolysis GO:0051044 10.11 TNF IL1B IFNG
20 positive regulation of heterotypic cell-cell adhesion GO:0034116 10.1 TNF IL1B IL10
21 positive regulation of immunoglobulin production GO:0002639 10.1 TLR9 IL6 IL5 IL10
22 astrocyte activation GO:0048143 10.09 TNF IL1B IFNG
23 positive regulation of MHC class II biosynthetic process GO:0045348 10.09 IL4 IL10 IFNG
24 positive regulation of podosome assembly GO:0071803 10.08 TNF IL5 CSF2
25 microglial cell activation GO:0001774 10.08 TNF TLR9 IL4 IFNG
26 negative regulation of neurogenesis GO:0050768 10.06 CCL11 IL1B IL6 TNF
27 response to molecule of bacterial origin GO:0002237 10.05 TLR9 IL10 CXCL8
28 positive regulation of neuroinflammatory response GO:0150078 10.04 IL1B IL6 TNF
29 negative regulation of lipid storage GO:0010888 10.03 TNF IL6 CRP
30 positive regulation of cytokine production GO:0001819 10.03 TNF TLR9 IL1B IL10 IFNG
31 positive regulation of mononuclear cell migration GO:0071677 9.99 TNF IL4
32 negative regulation of cytokine production involved in immune response GO:0002719 9.99 TNF IL10
33 vascular endothelial growth factor production GO:0010573 9.99 IL1B IL6 TNF
34 positive regulation of fever generation GO:0031622 9.98 IL1B TNF
35 sequestering of triglyceride GO:0030730 9.97 IL1B TNF
36 regulation of isotype switching GO:0045191 9.97 IL10 IL4
37 cellular response to lipopolysaccharide GO:0071222 9.97 CSF2 CXCL8 IL10 IL1B IL6 TLR9
38 positive regulation of nitrogen compound metabolic process GO:0051173 9.96 TNF IFNG
39 chronic inflammatory response to antigenic stimulus GO:0002439 9.96 IL10 TNF
40 positive regulation of vitamin D biosynthetic process GO:0060557 9.95 IFNG TNF
41 positive regulation of chemokine production GO:0032722 9.91 TNF TLR9 IL6 IL1B IFNG
42 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.85 TNF IL1B IFNG
43 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.73 TNF IL6 IL4 IL3 IFNG CSF2
44 immune response GO:0006955 9.55 TNF TLR9 IL6 IL5 IL4 IL3

Molecular functions related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.73 IL6 IL5 IL4 IL3 IL10 CSF2
2 cytokine activity GO:0005125 9.66 TNF IL6 IL5 IL4 IL3 IL1B

Sources for Gastroenteritis

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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