MCID: GST045
MIFTS: 59

Gastroenteritis

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastroenteritis

MalaCards integrated aliases for Gastroenteritis:

Name: Gastroenteritis 12 74 54 42 43 15 17 71
Cholera Morbus 12 71
Infectious Colitis, Enteritis and Gastroenteritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2326
MeSH 43 D005759
NCIt 49 C34632
SNOMED-CT 67 25374005
ICD10 32 K52.9
UMLS 71 C0017160 C0206151

Summaries for Gastroenteritis

MedlinePlus : 42 Have you ever had the "stomach flu?" What you probably had was gastroenteritis - not a type of flu at all. Gastroenteritis is an inflammation of the lining of the intestines caused by a virus, bacteria, or parasites. Viral gastroenteritis is the second most common illness in the U.S. The cause is often a norovirus infection. It spreads through contaminated food or water or by contact with an infected person. The best prevention is frequent hand washing. Symptoms of gastroenteritis include diarrhea, abdominal pain, vomiting, headache, fever, and chills. Most people recover with no treatment. The most common problem with gastroenteritis is dehydration. This happens if you do not drink enough fluids to replace what you lose through vomiting and diarrhea. Dehydration is most common in babies, young children, older adults, and people with weak immune systems. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Gastroenteritis, also known as cholera morbus, is related to eosinophilic gastroenteritis and listeriosis, and has symptoms including nausea and vomiting, constipation and fever. An important gene associated with Gastroenteritis is LACTB (Lactamase Beta), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Fentanyl and Scopolamine have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and kidney, and related phenotypes are Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) and cardiovascular system

Disease Ontology : 12 A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. Chemicals and drugs also cause gastroenteritis. The symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen.

Wikipedia : 74 Gastroenteritis, also known as infectious diarrhea, is inflammation of the gastrointestinal tract-the... more...

Related Diseases for Gastroenteritis

Diseases related to Gastroenteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1026)
# Related Disease Score Top Affiliating Genes
1 eosinophilic gastroenteritis 34.7 RNASE3 IL5 IL4 IL3 CSF2 CCL11
2 listeriosis 33.2 TNF IL6 IL10
3 influenza 33.2 TNF IL6 IL1B IFNG CXCL8
4 shigellosis 33.2 TNF IL1B IL10 CXCL8 ALB
5 dysentery 33.0 TNF IL6 IL1B IL10 CXCL8 CRP
6 diarrhea 32.2 TNF IL6 IL5 IL1B IL10 IFNG
7 ileitis 32.0 TNF IL6 IL10 CSF2
8 colitis 31.8 TNF TLR9 IL6 IL4 IL1B IL10
9 intussusception 31.6 IL6 CRP ALB
10 cholera 31.5 TNF IL6 IL4 CXCL8
11 irritable bowel syndrome 31.5 TNF TLR9 IL6 IL10 CXCL8
12 lactose intolerance 31.4 IL10 CRP ANPEP ALB
13 hypereosinophilic syndrome 31.4 RNASE3 IL5 IL4 IL3 IL10 IFNG
14 intestinal obstruction 31.4 IL6 CRP ALB
15 esophagitis, eosinophilic, 1 31.4 RNASE3 IL5 IL4 IL3 CCL11
16 gastritis 31.4 TNF IL6 IL1B IL10 CXCL8 CAT
17 salmonellosis 31.3 TNF TLR9 LACTB IL6 IL1B IL10
18 encephalitis 31.2 TNF IL6 IL1B IL10
19 intestinal perforation 31.2 IL6 CRP ALB
20 esophagitis 31.2 TNF IL6 IL5 IL4 IL1B IL10
21 ige responsiveness, atopic 31.2 RNASE3 IL5 IL4 IL10 IFNG
22 toxic megacolon 31.1 TNF CRP ALB
23 hepatitis a 31.1 TNF IL4 IL10 IFNG ALB
24 acute pancreatitis 31.1 TNF IL6 IL1B IL10 CXCL8 CRP
25 gastric ulcer 31.0 TNF IL6 IL1B CXCL8
26 cholecystitis 31.0 RNASE3 CAT ANPEP ALB
27 amebiasis 31.0 TNF IL4 CXCL8 ALB
28 purpura 31.0 TNF IL6 IL4 IL10 CRP
29 iron deficiency anemia 31.0 TNF IL6 CRP CAT
30 typhoid fever 31.0 TNF IL6 IL1B IFNG CRP ALB
31 peritonitis 31.0 TNF IL6 IL4 IL1B IL10 IFNG
32 food allergy 31.0 TNF RNASE3 IL5 IL4 IL10 IFNG
33 reactive arthritis 31.0 TNF IL6 IL1B IL10 IFNG CXCL8
34 duodenal ulcer 30.9 TNF IL6 IL1B IL10 CXCL8 CAT
35 erysipelas 30.9 TNF IL6 CRP CAT
36 plague 30.9 TNF TLR9 IL6 IL10 ALB
37 severe acute respiratory syndrome 30.9 TNF IL6 IL10 IFNG CXCL8 CRP
38 clostridium difficile colitis 30.9 IL1B CRP ALB
39 milk allergy 30.9 TNF RNASE3 IL5 IL4 IL10
40 graft-versus-host disease 30.9 TNF IL6 IL1B IL10 IFNG
41 disseminated intravascular coagulation 30.9 TNF IL6 IL10 CRP
42 appendicitis 30.8 TNF IL6 IL1B IL10 IFNG CXCL8
43 ileus 30.8 TNF IL6 IL1B IL10 IFNG CSF2
44 cystitis 30.8 TNF IL6 IL4 CXCL8 CRP
45 urticaria 30.8 TNF RNASE3 IL6 IL5 IL4 CRP
46 meningoencephalitis 30.8 TNF IL6 IL10 CRP ALB
47 obstructive jaundice 30.8 TNF IL6 CXCL8 CRP ALB
48 perinatal necrotizing enterocolitis 30.8 TNF TLR9 IL6 IL1B IL10 CXCL8
49 hydronephrosis 30.8 IL6 CXCL8 CRP ALB
50 cytomegalovirus infection 30.8 TNF IL6 IL1B CXCL8

Graphical network of the top 20 diseases related to Gastroenteritis:



Diseases related to Gastroenteritis

Symptoms & Phenotypes for Gastroenteritis

UMLS symptoms related to Gastroenteritis:


nausea and vomiting, constipation, fever, abdominal pain, pruritus, diarrhea, icterus, signs and symptoms, digestive, dyspepsia, heartburn, gastrointestinal gas, gastric irritation, abdominal cramps

GenomeRNAi Phenotypes related to Gastroenteritis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death in breast cancer cell lines (MCF10A, MDA-MB-435) GR00104-A-0 8.92 CAT CSF2 CXCL8 TNF

MGI Mouse Phenotypes related to Gastroenteritis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.1 ALB ANPEP CRP CSF2 IFNG IL10
2 homeostasis/metabolism MP:0005376 10.07 ALB CAT CRP CSF2 IFNG IL10
3 hematopoietic system MP:0005397 10.06 ANPEP CCL11 CSF2 IFNG IL10 IL1B
4 digestive/alimentary MP:0005381 10.02 ALB FUT2 IFNG IL10 IL4 IL5
5 immune system MP:0005387 10 ALB ANPEP CCL11 CRP CSF2 FUT2
6 neoplasm MP:0002006 9.61 ALB CAT CSF2 IFNG IL10 IL1B
7 respiratory system MP:0005388 9.23 CCL11 CSF2 IFNG IL10 IL4 IL5

Drugs & Therapeutics for Gastroenteritis

Drugs for Gastroenteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 240)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
2
Scopolamine Approved, Investigational Phase 4 51-34-3, 6533-68-2 5184
3
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
4
Ondansetron Approved Phase 4 99614-02-5 4595
5
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
6
Sodium citrate Approved, Investigational Phase 4 68-04-2
7
Dimenhydrinate Approved Phase 4 523-87-5 441281
8
Loperamide Approved Phase 4 53179-11-6 3955
9
Metoclopramide Approved, Investigational Phase 4 364-62-5 4168
10
Aluminum hydroxide Approved, Investigational Phase 4 21645-51-2
11
tannic acid Approved Phase 4 1401-55-4
12
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
13
Sorbitol Approved Phase 4 50-70-4 5780
14
Calcium carbonate Approved, Investigational Phase 4 471-34-1
15 Hydrotalcite Approved, Experimental, Investigational Phase 4 12304-65-3
16
Magnesium hydroxide Approved, Investigational Phase 4 1309-42-8
17
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
18
Sucralfate Approved Phase 4 54182-58-0
19
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
20
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
21
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
22
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
23
Ergocalciferol Approved, Nutraceutical Phase 4 50-14-6 5280793
24
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4 1406-16-2
25
Vitamin D3 Approved, Nutraceutical Phase 4 67-97-0 6221 5280795
26 Thiorphan Experimental Phase 4 76721-89-6
27
Racecadotril Investigational Phase 4 81110-73-8
28 Adjuvants, Anesthesia Phase 4
29 Muscarinic Antagonists Phase 4
30 Butylscopolammonium Bromide Phase 4
31 Cholinergic Agents Phase 4
32 Anesthetics Phase 4
33 Cholinergic Antagonists Phase 4
34 Bromides Phase 4
35 Parasympatholytics Phase 4
36 Acidophilus Phase 4
37 Dextrans Phase 4
38 Anti-Anxiety Agents Phase 4
39 Antipsychotic Agents Phase 4
40 Tranquilizing Agents Phase 4
41 Psychotropic Drugs Phase 4
42 Serotonin Agents Phase 4
43 Central Nervous System Depressants Phase 4
44 Serotonin Antagonists Phase 4
45 Vaccines Phase 4
46 Bifidobacterium Phase 4
47 Dopamine Antagonists Phase 4
48 Dopamine Agents Phase 4
49 Citrate Phase 4
50 Antidiarrheals Phase 4

Interventional clinical trials:

(show top 50) (show all 356)
# Name Status NCT ID Phase Drugs
1 Assessment of Analgesic Efficacy and Safety of Intravenous Hyoscine-N-Butylbromide in Patients With Abdominal Colic Associated With Acute Gastroenteritis; a Randomized, Double-blind, Placebo Controlled Study Unknown status NCT02508142 Phase 4 Hyoscine-N-Butylbromide
2 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
3 Cross-reactive Immunity Elicited by Oral and Parenteral Typhoid Vaccines Against Non-typhoid Salmonellae Unknown status NCT02121145 Phase 4
4 Impact of Four Patient Information Leaflets (PIL) on Patient Behaviour : a Randomised Controlled Trial in Primary Care. Completed NCT01398696 Phase 4
5 Efficacy and Safety of Probiotics in the Treatment of Acute Gastroenteritis in Children Completed NCT03539913 Phase 4
6 Impact of Systematic Infants Vaccination Against Rotavirus on Gastroenteritis Hospitalization: a Prospective Study in Brest District, France. Completed NCT00740935 Phase 4
7 Comparison of Clinical Efficacy of Enteroadsorbent Polymethylsiloxane vs Probiotic Lactobacillus Reuteri in the Treatment of Rotaviral Gastroenteritis in Infants and Toddlers. Completed NCT04116307 Phase 4
8 Rapid Diagnostics and Probiotic Therapy for Paediatric Acute Gastroenteritis - a Randomized, Factorial, Controlled, Placebo-controlled, Pilot Trial Completed NCT02025452 Phase 4
9 Bacillus Clausii in the Treatment of Acute Community-acquired Diarrhea Among Latin American Children (cadiLAc) Completed NCT02169817 Phase 4 Bacillus clausii;Oral Rehydration Therapy
10 Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis: A Randomized Controlled Trial Completed NCT00392145 Phase 4 Standard IV rehydration;Rapid intravenous rehydration (RIVR)
11 A Randomized Double-blind Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Moderate Vomiting Due to Acute Gastroenteritis Completed NCT00124787 Phase 4 Dimenhydrinate;Placebo
12 Immunogenicity of the Human Rotavirus Vaccine (Rotarix™) at Varying Schedules, Doses, and Ages in Rural Ghana Completed NCT01575197 Phase 4
13 Immunogenicity, Reactogenicity and Safety Study to Evaluate Two Doses of the Lyophilised Formulation of the Human Rotavirus (HRV) Vaccine When Administered to Healthy Korean Infants Previously Uninfected With HRV Completed NCT00969228 Phase 4
14 Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis: A Double Blind Randomized, Placebo- Controlled Trial Completed NCT01657032 Phase 4
15 Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis: Randomized, Double-Blind Controlled Trial Completed NCT01467570 Phase 4
16 The Treatment Effect of Bio-Three on Children With Enteritis Due to Salmonella or Rotavirus or Any Unknown Reason Completed NCT01480947 Phase 4 Bio-three
17 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children: A Randomized Double-blind Trial Completed NCT01564290 Phase 4 Placebo probiotic
18 Ondansetron Vs Metoclopramide in the Treatment of Vomiting in Gastroenteritis Patients: A Randomized Controlled Trial Completed NCT01165866 Phase 4 Treatment 1. Metoclopramide;Treatment 2 Ondansetron
19 Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Under Six Months. Completed NCT01571856 Phase 4 Zinc Sulfate
20 The Immunogenicity of Rotavirus Vaccine Under Different Age Schedules and the Impact of Withholding Breast Feeding Around the Time of Vaccination on the Immunogenicity of Rotarix Vaccine Completed NCT01199874 Phase 4
21 Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in Emergency Departments in Pakistan Completed NCT01870648 Phase 4 Ondansetron;Placebo
22 Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in Emergency Departments in Pakistan Completed NCT01870635 Phase 4 Ondansetron;Placebo
23 An Open-label, Pilot Study to Compare the Safety and Immunogenicity of an Alternate Dosing Schedule (2-5 Weeks, 2 Months, and 4 Months) for Pentavalent Rotavirus Vaccine (RotaTeq) to the Standard Recommended Schedule (2, 4, and 6 Months) Completed NCT01960725 Phase 4
24 The Effect of a Probiotic and/or Prebiotic on the Duration of Diarrhea and Length of Hospital Stay in Children With Acute Diarrhea: Prospective, Double Blind, Randomized Controlled Trial Completed NCT01927094 Phase 4
25 Efficacy of Racecadotril in the Management of Acute Watery Diarrhea in Children Completed NCT01577043 Phase 4 Racecadotril
26 Introduction of an Oral Live Human Rotavirus (Rotarix) Vaccine in Matlab Completed NCT00737503 Phase 4
27 Lactobacillus Reuteri Reduces Pulmonary Exacerbations and Upper Respiratory Tract Infections in CF Patients With Mild-to-moderate Lung Disease. LR Administration Might Have a Beneficial Effect on the Disease Course of Cystic Fibrosis. Completed NCT01737983 Phase 4
28 The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease: a Placebo-controlled Randomized Trial Completed NCT02010762 Phase 4 Vitamin D;Placebo
29 Safety and Immunogenicity of Sequential Rotavirus Vaccine Schedules With RotaTeq® and Rotarix® Completed NCT01266850 Phase 4
30 A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment: Randomized Trial Completed NCT03635372 Phase 4 Alginate;Sucralfate;Hydrotalcite
31 Manipulation of Visceral Hypersensitivity With Probiotic Bacteria in Irritable Bowel Syndrome Completed NCT01139736 Phase 4
32 The ORVAC Trial: A Phase IV, Double-blind, Randomised, Placebo-controlled Clinical Trial of a Third Scheduled Dose of RV1 Rotavirus Vaccine in Australian Indigenous Infants to Improve Protection Against Gastroenteritis Recruiting NCT02941107 Phase 4 Rotarix (RV1);Placebo
33 Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features in a Primary Care Setting: A Pragmatic, Randomized, Single Blind Study Recruiting NCT04028466 Phase 4 Vonoprazan;Omeprazole
34 Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE) Not yet recruiting NCT04149470 Phase 4 Omeprazole 20mg BID
35 A Double-Blind, Randomized, Comparative Efficacy and Safety Trial of Intravenous Solutions for the Treatment of Moderate to Severe Dehydration in Children With Acute Gastroenteritis Terminated NCT01234883 Phase 4 multiple electrolyte solution;saline
36 The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors Terminated NCT01404832 Phase 4 Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms
37 Phase II Double Blind Placebo-controled Randomized Comparative Multicentered Study of Efficacy and Safety of Filtrum-STI, 0,4g Tablets (Produced by AVVA RUS) in Children With Viral Gastroenteritis Unknown status NCT01113346 Phase 2, Phase 3 Filtrum-STI (lignin hydrolytic);Placebo
38 Phase Three Clinical Trials of Trivalent Rotavirus Genetic Reassortment Vaccine Unknown status NCT01738074 Phase 3
39 A Phase III, Randomized, Double Blind, Placebo Controlled Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E, Against Severe Rotavirus Gastroenteritis in Infants Unknown status NCT01305109 Phase 3
40 Comparison of Efficacy of Ondansetron Versus Metoclopramide for Vomiting in Children With Acute Gastroenteritis: Randomized Controlled Clinical Trial Unknown status NCT02619201 Phase 3 Ondansetron;metoclopramide
41 Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis Completed NCT01773967 Phase 2, Phase 3 LGG;micro-crystalline cellulose
42 Randomized, Placebo-Controlled, Phase 3 Trial of BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis (The GUARD Study) Completed NCT02246439 Phase 3 RHB-102;Placebo Oral Tablet
43 A Multicenter, Double-Blind, Randomized Study to Compare The Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00392574 Phase 3 Prulifloxacin;Placebo
44 A Phase III Randomized, Placebo-controlled Clinical Trial to Study the Efficacy and Safety of V260 in Healthy Infants in Japan Completed NCT00718237 Phase 3
45 A Multicenter, Double-Blind, Randomized Study to Compare the Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00448422 Phase 3 prulifloxacin
46 The Implementation of a Gastroenteritis Education Program Completed NCT00311831 Phase 3
47 the Effectiveness of Echinacea, Propolis and Vitamin C in the Prevention of Respiratory Tract Infections and Gastroenteritis in Preschool Age Children: a Prospective Study Completed NCT00231218 Phase 3 dietary supplement--echinacea, propolis, and vitamin c
48 A Double-blind, Randomized, Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Immunogenicity of a New Formulation of RotaTeq™ Completed NCT01600092 Phase 3
49 Gelatin Tannate as Treatment for Acute Childhood Gastroenteritis: a Prospective, Randomized, Single-blind Controlled Clinical Trial Completed NCT02644200 Phase 3
50 A Phase II/III, Multicenter, Open-Label, Randomized Study of Liquid Bovine Rotavirus Pentavalent Vaccine (LBRV-PV) to Evaluate Lot-to-Lot Consistency and to Compare Non-Inferiority With ROTASIIL (Lyophilized BRV-PV) in Healthy Infants in India Completed NCT03474055 Phase 2, Phase 3

Search NIH Clinical Center for Gastroenteritis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


ERYTHROMYCIN PWDR

Cochrane evidence based reviews: gastroenteritis

Genetic Tests for Gastroenteritis

Anatomical Context for Gastroenteritis

MalaCards organs/tissues related to Gastroenteritis:

40
Testes, Colon, Kidney, Liver, Small Intestine, Bone, Breast

Publications for Gastroenteritis

Articles related to Gastroenteritis:

(show top 50) (show all 18852)
# Title Authors PMID Year
1
Genetic diversity of human adenovirus and human astrovirus in children with acute gastroenteritis in Northwest Ethiopia. 61 42
31570995 2019
2
Molecular epidemiology and clinical characteristics of norovirus gastroenteritis with seizures in children in Taiwan, 2006-2015. 61 42
31577718 2019
3
Rotavirus prevalence and seasonal distribution post vaccine introduction in Nairobi county Kenya. 61 42
31693717 2019
4
[Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus]. 54 61
19634766 2009
5
Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus. 54 61
17467767 2007
6
Nosocomial outbreak of pediatric gastroenteritis caused by CTX-M-14-type extended-spectrum beta-lactamase-producing strains of Salmonella enterica serovar London. 54 61
16000495 2005
7
Identification of a putative cellular receptor 150 kDa polypeptide for porcine epidemic diarrhea virus in porcine enterocytes. 54 61
14685034 2003
8
[A study of serum mitochondrial enzymes(mCK, mAST, mMDH) in rotavirus and adenovirus gastroenteritis in pediatric patients]. 54 61
11769565 2001
9
Interspecies aminopeptidase-N chimeras reveal species-specific receptor recognition by canine coronavirus, feline infectious peritonitis virus, and transmissible gastroenteritis virus. 54 61
8985407 1997
10
Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct from the enzymatic site. 54 61
7913510 1994
11
Rapid and specific detection of the thermostable direct haemolysin gene in Vibrio parahaemolyticus by the polymerase chain reaction. 54 61
8126441 1993
12
Biochemical and immunologic characterization of serum biotinidase in partial biotinidase deficiency. 54 61
1561012 1992
13
Characterization of Escherichia coli possessing the locus of heat resistance isolated from human cases of acute gastroenteritis. 61
31997757 2020
14
NKT cells are responsible for the clearance of murine norovirus through the virus-specific secretory IgA pathway. 61
31909227 2020
15
Full genome characterization of human G3P[6] and G3P[9] rotavirus strains in Lebanon. 61
31812761 2020
16
Myenteric networks of interstitial cells of Cajal are reduced in horses with inflammatory bowel disease. 61
31397916 2020
17
Gene Expression of Promyelocytic Leukemia Proteins and IFN-γ Is Reduced in Rotavirus-Infected Children 61
31677607 2020
18
Antimicrobial mechanism of strictinin isomers extracted from the root of Rosa roxburghii Tratt (Ci Li Gen). 61
31877366 2020
19
A Spanish case-control study in <5 year-old children reveals the lack of association between MLB and VA astrovirus and diarrhea. 61
32020041 2020
20
A Half Century of Oral Rehydration Therapy in Childhood Gastroenteritis: Toward Increasing Uptake and Improving Coverage. 61
31797188 2020
21
Gelatin tannate for acute diarrhoea and gastroenteritis in children: a systematic review and meta-analysis. 61
31272969 2020
22
Systematic analyses of factors required for adhesion of Salmonella enterica serovar Typhimurium to corn salad (Valerianella locusta). 61
32033951 2020
23
Emergence of fluoroquinolone resistant Campylobacter jejuni and Campylobacter coli among Australian chickens in the absence of fluoroquinolone use. 61
32033955 2020
24
Atypical Salmonella enterica serovars in murine and human macrophage infection models. 61
32014897 2020
25
Outer membrane protein OmpV mediates Salmonella enterica serovar typhimurium adhesion to intestinal epithelial cells via fibronectin and α1β1 integrin. 61
32017350 2020
26
Epidemiology of human giardiasis in Romania: A 14 years survey. 61
31791758 2020
27
Severe underlying liver diseases and high mortality associated with Laribacter hongkongensis bacteremia. 61
31787408 2020
28
Evaluation of the RIDA®GENE RT-PCR assays for detection of sapovirus, astrovirus, adenovirus, and rotavirus in stool samples of adults in Switzerland. 61
31757559 2020
29
Evidence of Saffold virus circulation in Italy provided through environmental surveillance. 61
31742735 2020
30
Norovirus Seroprevalence among Adults in the United States: Analysis of NHANES Serum Specimens from 1999-2000 and 2003-2004. 61
32033378 2020
31
Combinatorial Discriminant Analysis Applied to RNAseq Data Reveals a Set of 10 Transcripts as Signatures of Exposure of Cattle to Mycobacterium avium subsp. paratuberculosis. 61
32033399 2020
32
Rotavirus vaccination in the neonatal intensive care units: where are we? A rapid review of recent evidence. 61
31851055 2020
33
SoxS is a positive regulator of key pathogenesis genes and promotes intracellular replication and virulence of Salmonella Typhimurium. 61
31838175 2020
34
Human BCL10 Deficiency due to Homozygosity for a Rare Allele. 61
32008135 2020
35
Genetic diversity of group A rotaviruses in Moscow in 2018-2019. 61
32016546 2020
36
Understanding the penetrance of intrinsic protein disorder in rotavirus proteome. 61
31739058 2020
37
Comparative evaluation of structure and characteristic of peptidyl-prolyl cis-trans isomerase proteins and their function in Salmonella Typhimurium stress responses and virulence. 61
31111418 2020
38
Effects of rotavirus vaccine on all-cause acute gastroenteritis and rotavirus hospitalizations in Israel: A nationwide analysis. 61
32029322 2020
39
High prevalence of equine-like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand. 61
31498444 2020
40
Invasive Salmonella Enteritidis infection complicated by bacterial meningitis and vertebral osteomyelitis shortly after influenza A infection in an immunocompetent young adult. 61
31445818 2020
41
Fatal intestinal inflammatory lesions in equids in California: 710 cases (1990-2013). 61
31999521 2020
42
The impact of allergic rhinitis on gastrointestinal disorders among young adults. 61
30773746 2020
43
Impact of rotavirus vaccine on paediatric rotavirus hospitalisation and intussusception in New Zealand: A retrospective cohort study. 61
31889608 2020
44
Acute myocardial infarction in a young woman: Unexpected findings of a coronary occlusion. 61
31896072 2020
45
Vibrio cholera and V. parahaemolyticus coinfection in an oncology patient with gastroenteritis. 61
31740171 2020
46
Antimicrobial resistance in N'Djamena (Chad): Four-year experience of the French Forward Medical and Surgical Team engaged in the "Barkhane Operation". 61
32035720 2020
47
Immunosensor Based on Long-Period Fiber Gratings for Detection of Viruses Causing Gastroenteritis. 61
32028629 2020
48
National rotavirus vaccination programme implementation and gastroenteritis presentations: the paediatric emergency medicine perspective. 61
31197576 2020
49
Dynamics of transmissible gastroenteritis virus internalization unraveled by single-virus tracking in live cells. 61
32017270 2020
50
10-Year Rotavirus Infection Surveillance: Epidemiological Trends in the Pediatric Population of Perugia Province. 61
32033439 2020

Variations for Gastroenteritis

Expression for Gastroenteritis

Search GEO for disease gene expression data for Gastroenteritis.

Pathways for Gastroenteritis

Pathways related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.12 TNF TLR9 RNASE3 IL6 IL5 IL4
2
Show member pathways
13.9 TNF IL6 IL5 IL4 IL3 IL1B
3
Show member pathways
13.78 TNF IL6 IL5 IL4 IL3 IL1B
4
Show member pathways
13.65 TNF IL6 IL5 IL4 IL3 IL1B
5
Show member pathways
13.55 TNF TLR9 IL6 IL5 IL4 IL3
6
Show member pathways
13.5 TNF IL6 IL5 IL4 IL3 IL1B
7
Show member pathways
13.44 TNF IL6 IL5 IL4 IL3 IL1B
8
Show member pathways
13.21 TNF TLR9 IL6 IL1B IL10 IFNG
9 12.93 IL6 IL5 IL4 IL3 IFNG CXCL8
10
Show member pathways
12.91 TNF TLR9 IL6 IL1B IFNG CXCL8
11
Show member pathways
12.91 TNF RNASE3 IL6 IL5 IL4 IL3
12 12.85 TNF TLR9 IL6 IL1B IFNG
13
Show member pathways
12.82 TNF IL6 IL1B IFNG CXCL8
14
Show member pathways
12.77 TNF TLR9 IL6 IL3 IL1B
15
Show member pathways
12.77 TNF IL6 IL5 IL4 IL1B IL10
16
Show member pathways
12.76 TNF TLR9 IL6 IL5 IL4 IL1B
17 12.73 TNF TLR9 IL4 IL3 IL1B IL10
18
Show member pathways
12.67 TNF IL6 IL1B IL10 IFNG
19
Show member pathways
12.66 TNF IL5 IL4 IL3 CSF2
20
Show member pathways
12.6 TNF IL4 IL3 IFNG CSF2
21
Show member pathways
12.53 IL6 IL5 IL4 IL3 IL10 IFNG
22
Show member pathways
12.52 TNF IL6 IL4 IL1B IFNG CRP
23
Show member pathways
12.45 TNF IL6 IL10 CXCL8 CCL11
24
Show member pathways
12.44 TNF IL6 IL5 IL4 IL1B IFNG
25 12.43 TNF IL1B CXCL8 CSF2
26
Show member pathways
12.42 TNF IL6 IL5 IL4 IL3 IL1B
27
Show member pathways
12.41 TNF IL6 IL1B IFNG CXCL8
28 12.4 TNF TLR9 IL6 IL1B IL10 IFNG
29
Show member pathways
12.39 TNF IL4 IL1B IL10 IFNG
30 12.36 TNF IL6 IL1B CXCL8
31
Show member pathways
12.36 TNF TLR9 IL6 IL4 IL1B IFNG
32
Show member pathways
12.34 TNF TLR9 IL6 IL1B IL10
33
Show member pathways
12.33 TNF TLR9 IL6 CXCL8
34 12.32 IL6 IL3 CXCL8 CSF2
35 12.31 TNF IL6 IL1B CXCL8
36 12.31 TNF IL6 IL1B IL10 CXCL8
37
Show member pathways
12.29 TNF IL6 IL1B CXCL8
38 12.26 TNF TLR9 IL6 IFNG
39
Show member pathways
12.25 TNF TLR9 IL6 IL1B IL10 IFNG
40
Show member pathways
12.22 TNF IL6 IL4 IL1B IFNG CSF2
41 12.2 TNF IL6 IL4 IL1B IFNG CXCL8
42 12.18 TNF IL6 IL4 IL1B IL10 CXCL8
43 12.17 TNF IL6 IL1B IL10 CXCL8
44 12.11 IL6 IL3 IL1B IFNG CXCL8
45 12.1 TNF IL6 IL1B IL10 IFNG CXCL8
46 12.07 TNF IL6 IL1B CSF2
47 12.07 TNF IL6 IL1B IFNG CXCL8 CSF2
48 12.02 TNF IL6 IL1B CXCL8
49 12 IL6 IL5 IL4 IFNG CXCL8 CSF2
50 11.99 TNF IL5 IL4 IL1B IL10 IFNG

GO Terms for Gastroenteritis

Cellular components related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 TNF TLR9 RNASE3 IL6 IL5 IL4
2 extracellular space GO:0005615 9.53 TNF RNASE3 IL6 IL5 IL4 IL3

Biological processes related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 55)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription, DNA-templated GO:0045893 10.16 TNF IL6 IL5 IL4 IL1B IL10
2 positive regulation of cell proliferation GO:0008284 10.13 IL6 IL5 IL3 IL1B IFNG CSF2
3 MAPK cascade GO:0000165 10.03 TNF IL5 IL3 IL1B CSF2
4 defense response to Gram-positive bacterium GO:0050830 9.93 TNF RNASE3 IL6 CRP
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.93 TNF TLR9 IL6 IL1B CAT
6 positive regulation of gene expression GO:0010628 9.92 TNF TLR9 IL6 IL4 IL1B IFNG
7 regulation of insulin secretion GO:0050796 9.89 TNF IL1B IFNG
8 response to glucocorticoid GO:0051384 9.89 TNF IL6 IL10
9 positive regulation of T cell proliferation GO:0042102 9.88 IL6 IL4 IL1B
10 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.88 TNF TLR9 IL1B
11 positive regulation of interleukin-6 production GO:0032755 9.88 TNF TLR9 IL6 IL1B
12 positive regulation of DNA-binding transcription factor activity GO:0051091 9.88 TNF IL6 IL5 IL1B IL10
13 cellular response to lipopolysaccharide GO:0071222 9.88 TNF IL6 IL1B IL10 CXCL8 CSF2
14 humoral immune response GO:0006959 9.87 TNF IL6 IFNG
15 positive regulation of phagocytosis GO:0050766 9.86 TNF IL1B IFNG
16 positive regulation of nitric oxide biosynthetic process GO:0045429 9.85 TNF IL1B IFNG
17 positive regulation of B cell proliferation GO:0030890 9.84 TLR9 IL5 IL4
18 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.83 TNF IL1B CSF2
19 negative regulation of interleukin-6 production GO:0032715 9.83 TNF TLR9 IL10
20 positive regulation of interleukin-8 production GO:0032757 9.81 TNF TLR9 IL1B
21 inflammatory response GO:0006954 9.81 TNF TLR9 IL6 IL5 IL1B IL10
22 positive regulation of chemokine production GO:0032722 9.79 TNF TLR9 IL6
23 positive regulation of glial cell proliferation GO:0060252 9.78 TNF IL6 IL1B
24 astrocyte activation GO:0048143 9.77 TNF IL1B IFNG
25 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.77 TNF IL1B IFNG
26 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.76 TNF IL1B IL10
27 positive regulation of JAK-STAT cascade GO:0046427 9.76 TNF IL6 IL5 IL10
28 positive regulation of neuroinflammatory response GO:0150078 9.74 TNF IL6 IL1B
29 positive regulation of podosome assembly GO:0071803 9.73 TNF IL5 CSF2
30 negative regulation of neurogenesis GO:0050768 9.73 TNF IL6 IL1B CCL11
31 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.73 TNF IL6 IL4 IL3 IFNG CSF2
32 negative regulation of amyloid-beta clearance GO:1900222 9.72 TNF IFNG
33 negative regulation of tumor necrosis factor biosynthetic process GO:0042536 9.72 IL4 IL10
34 response to molecule of bacterial origin GO:0002237 9.72 TLR9 IL10 CXCL8
35 negative regulation of interleukin-8 production GO:0032717 9.71 TLR9 IL10
36 endothelial cell apoptotic process GO:0072577 9.71 TNF IL10
37 regulation of establishment of endothelial barrier GO:1903140 9.7 TNF IL1B
38 negative regulation of cytokine secretion involved in immune response GO:0002740 9.7 TNF IL10
39 positive regulation of chemokine biosynthetic process GO:0045080 9.7 TNF IL1B IFNG
40 neuroinflammatory response GO:0150076 9.69 IL4 IFNG
41 type 2 immune response GO:0042092 9.69 IL4 IL10
42 positive regulation of interleukin-23 production GO:0032747 9.69 IFNG CSF2
43 positive regulation of MHC class II biosynthetic process GO:0045348 9.69 IL4 IL10 IFNG
44 positive regulation of fever generation GO:0031622 9.68 TNF IL1B
45 positive regulation of cellular respiration GO:1901857 9.67 IL4 IFNG
46 regulation of isotype switching GO:0045191 9.67 IL4 IL10
47 sequestering of triglyceride GO:0030730 9.67 TNF IL1B
48 negative regulation of lipid storage GO:0010888 9.67 TNF IL6 CRP
49 receptor biosynthetic process GO:0032800 9.65 TNF IL10
50 cytokine-mediated signaling pathway GO:0019221 9.65 TNF IL6 IL5 IL4 IL3 IL1B

Molecular functions related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.43 IL6 IL5 IL4 IL3 IL10 CSF2
2 cytokine activity GO:0005125 9.36 TNF IL6 IL5 IL4 IL3 IL1B

Sources for Gastroenteritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....