MCID: GST045
MIFTS: 58

Gastroenteritis

Categories: Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Gastroenteritis

MalaCards integrated aliases for Gastroenteritis:

Name: Gastroenteritis 12 74 54 42 44 15 17 71
Cholera Morbus 12 71
Infectious Colitis, Enteritis and Gastroenteritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2326
MeSH 44 D005759
NCIt 50 C34632
SNOMED-CT 67 154278002
ICD10 32 K52.9
UMLS 71 C0017160 C0206151

Summaries for Gastroenteritis

MedlinePlus : 42 Have you ever had the "stomach flu?" What you probably had was gastroenteritis - not a type of flu at all. Gastroenteritis is an inflammation of the lining of the intestines caused by a virus, bacteria, or parasites. Viral gastroenteritis is the second most common illness in the U.S. The cause is often a norovirus infection. It spreads through contaminated food or water or by contact with an infected person. The best prevention is frequent hand washing. Symptoms of gastroenteritis include diarrhea, abdominal pain, vomiting, headache, fever, and chills. Most people recover with no treatment. The most common problem with gastroenteritis is dehydration. This happens if you do not drink enough fluids to replace what you lose through vomiting and diarrhea. Dehydration is most common in babies, young children, older adults, and people with weak immune systems. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Gastroenteritis, also known as cholera morbus, is related to eosinophilic gastroenteritis and shigellosis, and has symptoms including nausea and vomiting, constipation and fever. An important gene associated with Gastroenteritis is LACTB (Lactamase Beta), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Fentanyl and Loperamide have been mentioned in the context of this disorder. Affiliated tissues include kidney, breast and bone marrow, and related phenotypes are digestive/alimentary and immune system

Disease Ontology : 12 A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. Chemicals and drugs also cause gastroenteritis. The symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen.

Wikipedia : 74 Gastroenteritis, also known as infectious diarrhea and gastro, is inflammation of the gastrointestinal... more...

Related Diseases for Gastroenteritis

Diseases related to Gastroenteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1122)
# Related Disease Score Top Affiliating Genes
1 eosinophilic gastroenteritis 32.9 RNASE3 IL5 IL4 IL3 EPX CCL11
2 shigellosis 32.1 TNF IL1B IL10 CXCL8 ALB
3 listeriosis 32.1 TNF IL6 IL1B IL10
4 influenza 32.0 TNF IL6 IL1B IFNG IFNA1
5 dysentery 32.0 TNF IL6 IL1B IL10 CXCL8 CRP
6 diarrhea 31.4 TNF IL6 IL5 IL1B IL10 IFNG
7 intussusception 31.2 IL6 CRP ALB
8 gastritis 31.2 TNF IL6 IL1B IL10 CXCL8
9 cholera 31.2 TNF IL6 IL5 IL4 IL1B IL10
10 lactose intolerance 31.1 IL10 CRP ANPEP ALB
11 intestinal obstruction 31.1 IL6 CRP ALB
12 hypereosinophilic syndrome 31.1 RNASE3 IL5 IL4 IL3 IL10 IFNG
13 enterocolitis 31.0 TNF IL6 IL10 CXCL8 CRP
14 salmonellosis 31.0 TNF LACTB IL6 IL1B IL10 IFNG
15 campylobacteriosis 31.0 IL1B IL10 IFNG
16 irritable bowel syndrome 31.0 TNF IL6 IL4 IL1B IL10 CXCL8
17 pancreatitis 31.0 TNF IL6 IL1B IL10 CRP
18 colitis 31.0 TNF TLR9 IL6 IL4 IL1B IL10
19 esophagitis, eosinophilic, 1 30.9 RNASE3 IL5 IL4 IL3 EPX CCL11
20 ige responsiveness, atopic 30.8 RNASE3 IL5 IL4 IL10 IFNG
21 acute pancreatitis 30.8 TNF IL6 IL1B IL10 CXCL8 CRP
22 duodenal ulcer 30.8 TNF IL6 IL1B IL10 CXCL8
23 eosinophilic gastritis 30.8 IL5 EPX CCL11
24 peritonitis 30.8 TNF IL6 IL4 IL1B IL10 CXCL8
25 ileus 30.8 TNF IL6 IL1B IL10 CRP
26 esophagitis 30.8 TNF RNASE3 IL6 IL5 IL4 IL1B
27 helicobacter pylori infection 30.8 TNF IL1B IL10 CXCL8
28 intestinal perforation 30.7 TNF IL6 CRP ALB
29 toxic megacolon 30.7 TNF CRP ALB
30 encephalitis 30.7 TNF IL6 IL1B IL10
31 typhoid fever 30.7 TNF IL6 IL1B IFNG CRP ALB
32 erythema nodosum 30.7 TNF IL6 IL1B IL10 IFNG CXCL8
33 iron deficiency anemia 30.7 TNF IL6 CRP
34 reactive arthritis 30.7 TNF IL6 IL1B IL10 IFNG CXCL8
35 gastric ulcer 30.7 TNF IL6 IL1B CXCL8
36 erysipelas 30.6 TNF IL6 IL1B CRP
37 plague 30.6 TNF IL6 IL1B IL10 ALB
38 appendicitis 30.6 TNF IL6 IL1B IL10 IFNG CXCL8
39 graft-versus-host disease 30.6 TNF IL6 IL1B IL10 IFNG
40 bacterial infectious disease 30.6 TNF TLR9 IL6 IL3 IL1B IL10
41 urolithiasis 30.5 IL6 IL1B ALB
42 milk allergy 30.5 TNF RNASE3 IL5 IL4 IL10
43 disseminated intravascular coagulation 30.5 TNF IL6 IL10 CRP
44 food allergy 30.5 TNF RNASE3 IL5 IL4 IL10 IFNG
45 clostridium difficile colitis 30.5 IL1B CRP ALB
46 urticaria 30.5 TNF RNASE3 IL6 IL5 IL4 CRP
47 hepatitis a 30.5 TNF IL4 IL1B IL10 IFNG IFNA1
48 duodenitis 30.5 TNF CRP ALB
49 cystitis 30.5 TNF IL6 IL4 CXCL8 CRP
50 meningoencephalitis 30.5 TNF IL6 IL10 CRP ALB

Graphical network of the top 20 diseases related to Gastroenteritis:



Diseases related to Gastroenteritis

Symptoms & Phenotypes for Gastroenteritis

UMLS symptoms related to Gastroenteritis:


nausea and vomiting, constipation, fever, abdominal pain, pruritus, diarrhea, dyspepsia, abdominal cramps, icterus, signs and symptoms, digestive, heartburn, gastrointestinal gas, gastric irritation

MGI Mouse Phenotypes related to Gastroenteritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.81 ALB FUT2 IFNG IL10 IL4 IL5
2 immune system MP:0005387 9.8 ALB ANPEP CCL11 CRP EPX FUT2
3 neoplasm MP:0002006 9.17 ALB IFNG IL10 IL1B IL5 IL6

Drugs & Therapeutics for Gastroenteritis

Drugs for Gastroenteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 142)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
2
Loperamide Approved Phase 4 53179-11-6 3955
3
Zinc sulfate Approved, Investigational Phase 4 7733-02-0
4
Zinc Approved, Investigational Phase 4 7440-66-6 32051
5
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
6
Metoclopramide Approved, Investigational Phase 4 364-62-5 4168
7
Dimenhydrinate Approved Phase 4 523-87-5 441281
8
Histamine Approved, Investigational Phase 4 51-45-6, 75614-87-8 774
9
Scopolamine Approved, Investigational Phase 4 51-34-3, 6533-68-2 5184
10
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
11
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 68-26-8, 11103-57-4 445354
12
Racecadotril Investigational Phase 4 81110-73-8
13 Analgesics Phase 4
14 Gastrointestinal Agents Phase 4
15 Dermatologic Agents Phase 4
16 Antidiarrheals Phase 4
17 Dopamine Agents Phase 4
18 Dopamine Antagonists Phase 4
19 Emetics Phase 4
20 Histamine Antagonists Phase 4
21
Histamine Phosphate Phase 4 51-74-1 65513
22 Histamine H1 Antagonists Phase 4
23
protease inhibitors Phase 4
24 HIV Protease Inhibitors Phase 4
25 Nutrients Phase 4
26 Micronutrients Phase 4
27 Protective Agents Phase 4
28 Antioxidants Phase 4
29 Trace Elements Phase 4
30 Vitamins Phase 4
31 Parasympatholytics Phase 4
32 Muscarinic Antagonists Phase 4
33 Mydriatics Phase 4
34 Anesthetics Phase 4
35 Cholinergic Antagonists Phase 4
36 Cholinergic Agents Phase 4
37 Butylscopolammonium Bromide Phase 4
38 Bromides Phase 4
39 retinol Phase 4
40 Retinol palmitate Phase 4
41 Ophthalmic Solutions Phase 4
42 Pharmaceutical Solutions Phase 4
43 Plasma-lyte 148 Phase 4
44
Echinacea Approved, Experimental Phase 3
45 Orange Approved Phase 2, Phase 3
46
Sodium citrate Approved, Investigational Phase 3 68-04-2
47
Nitazoxanide Approved, Investigational, Vet_approved Phase 2, Phase 3 55981-09-4 41684
48
Somatostatin Approved, Investigational Phase 3 51110-01-1, 38916-34-6 53481605
49
Everolimus Approved Phase 3 159351-69-6 6442177 70789204
50 Benralizumab Approved, Investigational Phase 2, Phase 3 1044511-01-4

Interventional clinical trials:

(show top 50) (show all 222)
# Name Status NCT ID Phase Drugs
1 Assessment of Analgesic Efficacy and Safety of Intravenous Hyoscine-N-Butylbromide in Patients With Abdominal Colic Associated With Acute Gastroenteritis; a Randomized, Double-blind, Placebo Controlled Study Unknown status NCT02508142 Phase 4 Hyoscine-N-Butylbromide
2 Impact of Systematic Infants Vaccination Against Rotavirus on Gastroenteritis Hospitalization: a Prospective Study in Brest District, France. Completed NCT00740935 Phase 4
3 Rapid Diagnostics and Probiotic Therapy for Paediatric Acute Gastroenteritis - a Randomized, Factorial, Controlled, Placebo-controlled, Pilot Trial Completed NCT02025452 Phase 4
4 Impact of Four Patient Information Leaflets (PIL) on Patient Behaviour : a Randomised Controlled Trial in Primary Care. Completed NCT01398696 Phase 4
5 The Treatment Effect of Bio-Three on Children With Enteritis Due to Salmonella or Rotavirus or Any Unknown Reason Completed NCT01480947 Phase 4 Bio-three
6 Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in Emergency Departments in Pakistan Completed NCT01870648 Phase 4 Ondansetron;Placebo
7 Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in Emergency Departments in Pakistan Completed NCT01870635 Phase 4 Ondansetron;Placebo
8 Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis: A Randomized Controlled Trial Completed NCT00392145 Phase 4 Standard IV rehydration;Rapid intravenous rehydration (RIVR)
9 Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis: Randomized, Double-Blind Controlled Trial Completed NCT01467570 Phase 4
10 Ondansetron Vs Metoclopramide in the Treatment of Vomiting in Gastroenteritis Patients: A Randomized Controlled Trial Completed NCT01165866 Phase 4 Treatment 1. Metoclopramide;Treatment 2 Ondansetron
11 A Randomized Double-blind Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Moderate Vomiting Due to Acute Gastroenteritis Completed NCT00124787 Phase 4 Dimenhydrinate;Placebo
12 Efficacy and Safety of Probiotics in the Treatment of Acute Gastroenteritis in Children Completed NCT03539913 Phase 4
13 Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis: A Double Blind Randomized, Placebo- Controlled Trial Completed NCT01657032 Phase 4
14 Comparison of Clinical Efficacy of Enteroadsorbent Polymethylsiloxane vs Probiotic Lactobacillus Reuteri in the Treatment of Rotaviral Gastroenteritis in Infants and Toddlers. Completed NCT04116307 Phase 4
15 Bacillus Clausii in the Treatment of Acute Community-acquired Diarrhea Among Latin American Children (cadiLAc) Completed NCT02169817 Phase 4 Bacillus clausii;Oral Rehydration Therapy
16 The Immunogenicity of Rotavirus Vaccine Under Different Age Schedules and the Impact of Withholding Breast Feeding Around the Time of Vaccination on the Immunogenicity of Rotarix Vaccine Completed NCT01199874 Phase 4
17 Introduction of an Oral Live Human Rotavirus (Rotarix) Vaccine in Matlab Completed NCT00737503 Phase 4
18 Immunogenicity of the Human Rotavirus Vaccine (Rotarix™) at Varying Schedules, Doses, and Ages in Rural Ghana Completed NCT01575197 Phase 4
19 An Open-label, Pilot Study to Compare the Safety and Immunogenicity of an Alternate Dosing Schedule (2-5 Weeks, 2 Months, and 4 Months) for Pentavalent Rotavirus Vaccine (RotaTeq) to the Standard Recommended Schedule (2, 4, and 6 Months) Completed NCT01960725 Phase 4
20 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children: A Randomized Double-blind Trial Completed NCT01564290 Phase 4 Placebo probiotic
21 Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Under Six Months. Completed NCT01571856 Phase 4 Zinc Sulfate
22 Efficacy of Racecadotril in the Management of Acute Watery Diarrhea in Children Completed NCT01577043 Phase 4 Racecadotril
23 Management of Abdominal Pain in Acute Gastroenteritis Patients With Hyoscine Butylbromide: Randomized Double Blind Placebo Controlled Trial Recruiting NCT04682860 Phase 4 Hyoscine N Butylbromide
24 The ORVAC Trial: A Phase IV, Double-blind, Randomised, Placebo-controlled Clinical Trial of a Third Scheduled Dose of RV1 Rotavirus Vaccine in Australian Indigenous Infants to Improve Protection Against Gastroenteritis Recruiting NCT02941107 Phase 4 Rotarix (RV1);Placebo
25 The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children- a Randomized, Placebo-controlled, Double-blind Trial Recruiting NCT03988257 Phase 4
26 A Double-Blind, Randomized, Comparative Efficacy and Safety Trial of Intravenous Solutions for the Treatment of Moderate to Severe Dehydration in Children With Acute Gastroenteritis Terminated NCT01234883 Phase 4 multiple electrolyte solution;saline
27 Comparison of Efficacy of Ondansetron Versus Metoclopramide for Vomiting in Children With Acute Gastroenteritis: Randomized Controlled Clinical Trial Unknown status NCT02619201 Phase 3 Ondansetron;metoclopramide
28 Phase II Double Blind Placebo-controled Randomized Comparative Multicentered Study of Efficacy and Safety of Filtrum-STI, 0,4g Tablets (Produced by AVVA RUS) in Children With Viral Gastroenteritis Unknown status NCT01113346 Phase 2, Phase 3 Filtrum-STI (lignin hydrolytic);Placebo
29 A Phase III, Randomized, Double Blind, Placebo Controlled Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E, Against Severe Rotavirus Gastroenteritis in Infants Unknown status NCT01305109 Phase 3
30 the Effectiveness of Echinacea, Propolis and Vitamin C in the Prevention of Respiratory Tract Infections and Gastroenteritis in Preschool Age Children: a Prospective Study Completed NCT00231218 Phase 3 dietary supplement--echinacea, propolis, and vitamin c
31 Efficacy of Lactobacillus Reuteri DSM 17938 in the Prevention of Nosocomial Diarrhea in Children. Randomized Double-blind Placebo Controlled Trial Completed NCT01046656 Phase 3
32 Optimizing the Management of Pediatric Acute Diarrhoeal Disease in Botswana Completed NCT02803827 Phase 3
33 The Implementation of a Gastroenteritis Education Program Completed NCT00311831 Phase 3
34 A Multicenter, Double-Blind, Randomized Study to Compare the Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00448422 Phase 3 prulifloxacin
35 Oral Ondansetron vs Domperidone for Symptomatic Treatment of Vomiting During Acute Gastroenteritis in Children: Multicentre Randomized Controlled Trial Completed NCT01257672 Phase 3 Ondansetron;Domperidone;placebo
36 Phase III, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Live Attenuated Bovine-Human Rotavirus Reassortant Pentavalent Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Healthy Indian Infants Completed NCT02133690 Phase 3
37 Gelatin Tannate as Treatment for Acute Childhood Gastroenteritis: a Prospective, Randomized, Single-blind Controlled Clinical Trial Completed NCT02644200 Phase 3
38 Community Based Prophylaxis for Rotavirus Gastroenteritis in Children by an Anti-rotavirus Protein Based Food Supplement Completed NCT01265355 Phase 2, Phase 3
39 A Multicenter, Double-Blind, Randomized Study to Compare The Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00392574 Phase 3 Prulifloxacin;Placebo
40 Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis Completed NCT01773967 Phase 2, Phase 3 LGG;micro-crystalline cellulose
41 Randomized, Double-blind, Placebo-controlled Phase III Clinical Trial to Assess the Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis Among Infants in Niger Completed NCT02145000 Phase 3
42 Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis: Randomized Controlled Trial Completed NCT01853124 Phase 3 Placebo;Lacidofil
43 Randomized, Placebo-Controlled, Phase 3 Trial of BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis (The GUARD Study) Completed NCT02246439 Phase 3 RHB-102;Placebo Oral Tablet
44 Isotonic Versus Hypotonic Saline for Maintenance Intravenous Fluid Therapy: A Pilot Randomized Trial Completed NCT00457873 Phase 3 0.9% saline in 5% dextrose (intravenous);0.45% saline in 5% dextrose (intravenous)
45 A Phase III, Multicenter, Open Label, Randomized Study of Bovine Rotavirus Pentavalent Vaccine (BRV-PV) to Evaluate Lot-To-Lot Consistency and to Investigate Potential Interference With Routine UIP Vaccinations in Healthy Infants in India. Completed NCT02584816 Phase 3
46 A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy, Safety, and Immunogenicity of V260 in Healthy Chinese Infants Completed NCT02062385 Phase 3
47 An Open Label Study to Evaluate Immunogenicity, Safety, and Reactogenicity of Rotavac® (Live Attenuated Rotavirus Vaccine) as a 3-dose Series in Healthy Infants Aged Between 6 Weeks and 8 Weeks in Vietnam Completed NCT04596696 Phase 3
48 Phase III Comparative Study to Assess the Efficacy and Safety of Oral Rehydration Therapy (ORT) in Combination With Spores of Bacillus Clausii (Enterogermina)Versus ORT Alone, Administered for 5 Days With the Treatment of Acute Diarrhea in Children. Completed NCT00457353 Phase 3 Bacillus Clausii
49 A Phase II/III, Multicenter, Open-Label, Randomized Study of Liquid Bovine Rotavirus Pentavalent Vaccine (LBRV-PV) to Evaluate Lot-to-Lot Consistency and to Compare Non-Inferiority With ROTASIIL (Lyophilized BRV-PV) in Healthy Infants in India Completed NCT03474055 Phase 2, Phase 3
50 A Phase IIIb, Partially Blind, Randomized, Placebo-controlled Study to Asses the Effect on Immunogenicity of Administration of Vaccine Without Buffering Agent and to Assess Heat Stability in Terms of Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline Biologicals' Oral Live Attenuated Human Rotavirus (HRV) Vaccine Following a 0, 2 Month Schedule, in Healthy Infants Previously Uninfected With Human Rotavirus Completed NCT00169455 Phase 3

Search NIH Clinical Center for Gastroenteritis

Inferred drug relations via UMLS 71 / NDF-RT 51 :


ERYTHROMYCIN PWDR

Cochrane evidence based reviews: gastroenteritis

Genetic Tests for Gastroenteritis

Anatomical Context for Gastroenteritis

MalaCards organs/tissues related to Gastroenteritis:

40
Kidney, Breast, Bone Marrow, Small Intestine, Colon, T Cells, Skin

Publications for Gastroenteritis

Articles related to Gastroenteritis:

(show top 50) (show all 19935)
# Title Authors PMID Year
1
An acute gastroenteritis outbreak associated with breakfast contaminated with norovirus by asymptotic food handler at a kindergarten in Shenzhen, China. 42 61
33435906 2021
2
Acute Infectious Gastroenteritis in Infancy and Childhood. 42 61
33263539 2020
3
Enteric pathogen infection and consequences for child growth in young Aboriginal Australian children: a cross-sectional study. 42
33407180 2021
4
[Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus]. 54 61
19634766 2009
5
Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus. 61 54
17467767 2007
6
Nosocomial outbreak of pediatric gastroenteritis caused by CTX-M-14-type extended-spectrum beta-lactamase-producing strains of Salmonella enterica serovar London. 61 54
16000495 2005
7
Identification of a putative cellular receptor 150 kDa polypeptide for porcine epidemic diarrhea virus in porcine enterocytes. 54 61
14685034 2003
8
[A study of serum mitochondrial enzymes(mCK, mAST, mMDH) in rotavirus and adenovirus gastroenteritis in pediatric patients]. 54 61
11769565 2001
9
Interspecies aminopeptidase-N chimeras reveal species-specific receptor recognition by canine coronavirus, feline infectious peritonitis virus, and transmissible gastroenteritis virus. 54 61
8985407 1997
10
Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct from the enzymatic site. 61 54
7913510 1994
11
Rapid and specific detection of the thermostable direct haemolysin gene in Vibrio parahaemolyticus by the polymerase chain reaction. 54 61
8126441 1993
12
Biochemical and immunologic characterization of serum biotinidase in partial biotinidase deficiency. 54 61
1561012 1992
13
Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells. 61
33417512 2021
14
A simple and low-cost paper-based colorimetric method for detecting and distinguishing the GII.4 and GII.17 genotypes of norovirus. 61
33592726 2021
15
SARS-CoV-2 RNA detection in stool samples from acute gastroenteritis cases, Brazil. 61
33421163 2021
16
A 21-year retrospective analysis of environmental impacts on paediatric acute gastroenteritis in an affluent setting. 61
33183801 2021
17
Effects of Salmonella enterica serovar typhimurium sseK1 on macrophage inflammation-related cytokines and glycolysis. 61
33513526 2021
18
Construction, expression and purification of a novel CadF-based multiepitope antigen and its immunogenic polyclonal antibody specific to Campylobacter jejuni and Campylobacter coli. 61
33418060 2021
19
Effects of Hangeshashinto on the nasal physiological function: An in vitro study. 61
32859442 2021
20
Safety and effectiveness of a somatropin biosimilar in children requiring growth hormone treatment: second analysis of the PATRO Children study Italian cohort. 61
32557273 2021
21
Detection of Human Adenovirus, Rotavirus, and Enterovirus in Tap Water and Their Association with the Overall Quality of Water in Karachi, Pakistan. 61
33180282 2021
22
Human group A rotavirus P[25] VP8* specifically binds to A-type histo-blood group antigen. 61
33453651 2021
23
Relationship Between Rotavirus P[6] Infection in Korean Neonates and Histo-Blood Group Antigen: a Single-Center Study. 61
33063679 2021
24
Inference of Naturally Acquired Immunity Using a Self-matched Negative-Control Design. 61
33337670 2021
25
Optimisation of a PMAxx™-RT-qPCR Assay and the Preceding Extraction Method to Selectively Detect Infectious Murine Norovirus Particles in Mussels. 61
33389671 2021
26
Norovirus strains in patients with acute gastroenteritis in rural and low-income urban areas in northern Brazil. 61
33462673 2021
27
Molecular epidemiology and genetic diversity of norovirus infection in children hospitalized with acute gastroenteritis in East Java, Indonesia in 2015-2019. 61
33401005 2021
28
Risk Factors and Clinical Profile of Sapovirus-associated Acute Gastroenteritis in Early Childhood: A Nicaraguan Birth Cohort Study. 61
33464013 2021
29
Randomized, placebo-controlled trial of xyloglucan and gelose for the treatment of acute diarrhea in children. 61
33028102 2021
30
Hospital-based Surveillance for Pediatric Norovirus Gastroenteritis in Bangladesh, 2012-2016. 61
33264214 2021
31
Bacteriophage as an alternative to prevent reptile-associated Salmonella transmission. 61
33455089 2021
32
Replicative capacity of four porcine enteric coronaviruses in LLC-PK1 cells. 61
33492525 2021
33
Prevalence and antimicrobial susceptibility of Campylobacter isolated from retail chickens in Thailand. 61
33338980 2021
34
Unexplained peripheral blood eosinophilia with gastrointestinal symptoms. 61
33569877 2021
35
Pediatric Respiratory and Enteric Virus Acquisition and Immunogenesis in US Mothers and Children Aged 0-2: PREVAIL Cohort Study. 61
33576746 2021
36
Campylobacter coli strains from Brazil can invade phagocytic and epithelial cells and induce IL-8 secretion. 61
33590448 2021
37
Molecular investigation on the presence of canine parvovirus in Egypt. 61
33285387 2021
38
The anti-rotavirus effect of baicalin via the gluconeogenesis-related p-JNK-PDK1-AKT-SIK2 signaling pathway. 61
33567320 2021
39
The Changing Landscape of Pediatric Viral Enteropathogens in the Post-Rotavirus Vaccine Era. 61
32009161 2021
40
Levels of human Rotaviruses and Noroviruses GII in urban rivers running through the city mirror their infection prevalence in populations. 61
32920413 2021
41
Complete Genome Sequence of a Clinical Campylobacter Isolate Identical to a Novel Campylobacter Species. 61
33602730 2021
42
Surveillance and Molecular Characterization of Rotavirus Strains Circulating in Odisha, India after Introduction of Rotavac. 61
33564996 2021
43
Burden of infection in Australian infants. 61
32969131 2021
44
Rotavirus Genotype Trends from 2013 to 2018 and Vaccine Effectiveness in Southern Vietnam. 61
33596479 2021
45
Simultaneous norovirus outbreak in three Portuguese army bases in the Lisbon region, December 2017. 61
31278165 2021
46
Assessment of human norovirus inhibition in cabbage kimchi by electron beam irradiation using RT-qPCR combined with immunomagnetic separation. 61
33415724 2021
47
Post-operative fever (POF) after cardiac surgery in a low- and middle-income-country: 7-year institutional experience. 61
33558001 2021
48
Opinions and attitudes of Italian healthcare workers towards recommended but not compulsory rotavirus vaccination. 61
32614732 2021
49
Rotavirus Vaccination of Infants Delayed and Limited within the National Immunization Programme in the Netherlands: An Opportunity Lost. 61
33579025 2021
50
Recommendations for clinical research in children presenting to primary care out-of-hours services: a randomised controlled trial with parallel cohort study. 61
33293414 2021

Variations for Gastroenteritis

Expression for Gastroenteritis

Search GEO for disease gene expression data for Gastroenteritis.

Pathways for Gastroenteritis

Pathways related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 77)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
14.11 TNF TLR9 RNASE3 IL6 IL5 IL4
2
Show member pathways
13.88 TNF IL6 IL5 IL4 IL3 IL1B
3
Show member pathways
13.79 TNF IL6 IL5 IL4 IL3 IL1B
4
Show member pathways
13.66 TNF IL6 IL5 IL4 IL3 IL1B
5
Show member pathways
13.53 TNF TLR9 IL6 IL5 IL4 IL3
6
Show member pathways
13.49 TNF IL6 IL5 IL4 IL3 IL1B
7
Show member pathways
13.42 TNF IL6 IL5 IL4 IL3 IL1B
8
Show member pathways
13.18 TNF TLR9 IL6 IL1B IL10 IFNG
9 12.97 IL6 IL5 IL4 IL3 IFNG IFNA1
10
Show member pathways
12.95 TNF TLR9 IL6 IL1B IFNG IFNA1
11 12.9 TNF TLR9 IL6 IL1B IFNG IFNA1
12
Show member pathways
12.84 TNF TLR9 IL6 IL1B IFNA1 CXCL8
13
Show member pathways
12.8 TNF TLR9 IL6 IL1B CXCL8
14
Show member pathways
12.77 TNF TLR9 IL6 IL3 IL1B
15
Show member pathways
12.74 TNF IL6 IL5 IL4 IL1B IL10
16
Show member pathways
12.74 TNF TLR9 IL6 IL5 IL4 IL1B
17 12.71 TNF TLR9 IL4 IL3 IL1B IL10
18
Show member pathways
12.67 TNF IL6 IL1B IL10 IFNG
19
Show member pathways
12.61 TNF IL4 IL3 IFNG IFNA1
20
Show member pathways
12.59 IL6 IL5 IL4 IL3 IL10 IFNG
21
Show member pathways
12.5 TNF IL6 IL4 IL1B IFNG CRP
22
Show member pathways
12.46 TNF IL6 IL5 IL4 IL1B IFNG
23
Show member pathways
12.45 TNF IL6 IL10 CXCL8 CCL11
24
Show member pathways
12.42 TNF IL6 IL1B IFNG CXCL8
25
Show member pathways
12.39 TNF IL4 IL1B IL10 IFNG
26 12.38 TNF TLR9 IL6 IL1B IL10 IFNG
27 12.37 TNF IL6 IL1B IFNA1 CXCL8
28
Show member pathways
12.35 TNF TLR9 IL6 IL1B IL10
29
Show member pathways
12.33 TNF TLR9 IL6 CXCL8
30 12.32 TNF IL6 IL1B IL10 CXCL8
31
Show member pathways
12.28 TNF IL1B IFNG IFNA1
32 12.26 TNF TLR9 IL6 IFNG
33
Show member pathways
12.25 TNF TLR9 IL6 IL4 IL1B IFNG
34 12.23 TNF IL6 IL1B IL10 CXCL8
35
Show member pathways
12.23 TNF IL6 IL5 IL4 IL3 IL1B
36 12.19 TNF IL6 IL4 IL1B IFNG CXCL8
37
Show member pathways
12.18 TNF RNASE3 IL6 IL5 IL4 IL3
38 12.11 IL6 IL3 IL1B IFNG CXCL8
39 12.11 TNF IL6 IL4 IL1B IL10 CXCL8
40 12.1 TNF IL6 IL1B IL10 IFNG CXCL8
41 12.04 TNF IL6 IL1B IFNG CXCL8
42 12.03 TNF IL6 IL1B CXCL8
43
Show member pathways
12.03 TLR9 IL6 IL4 IL1B IFNG
44 12.02 TNF IL6 IL5 IL4 IL3 IL1B
45 11.98 IL6 IL5 IL4 IFNG CXCL8
46 11.96 TNF IL5 IL4 IL1B IL10 IFNG
47 11.94 TNF IL6 IL1B IL10 CXCL8
48
Show member pathways
11.93 TNF TLR9 IL6 IL1B IL10 IFNG
49
Show member pathways
11.92 TNF IL5 IL4 IL3 IFNG CXCL8
50 11.92 TNF IL6 IL5 IL4 IL3 IL10

GO Terms for Gastroenteritis

Cellular components related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 TNF TLR9 RNASE3 IL6 IL5 IL4
2 extracellular space GO:0005615 9.53 TNF RNASE3 IL6 IL5 IL4 IL3

Biological processes related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.33 TLR9 IL6 IL5 IL4 IL1B IL10
2 positive regulation of transcription, DNA-templated GO:0045893 10.18 TNF IL6 IL5 IL4 IL1B IL10
3 positive regulation of cell proliferation GO:0008284 10.14 IL6 IL5 IL4 IL3 IL1B IFNG
4 defense response to bacterium GO:0042742 10.04 TNF TLR9 RNASE3 IL10 EPX
5 defense response to virus GO:0051607 10.01 TLR9 IL6 IFNG IFNA1
6 cellular response to lipopolysaccharide GO:0071222 9.99 TNF IL6 IL1B IL10 CXCL8
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.98 TNF TLR9 IL6 IL1B
8 defense response GO:0006952 9.98 TNF IFNA1 EPX CXCL8
9 positive regulation of gene expression GO:0010628 9.97 TNF TLR9 IL6 IL4 IL1B IFNG
10 defense response to Gram-positive bacterium GO:0050830 9.94 TNF RNASE3 IL6 CRP
11 positive regulation of inflammatory response GO:0050729 9.92 TNF TLR9 IL1B IFNG
12 regulation of insulin secretion GO:0050796 9.91 TNF IL6 IL1B IFNG
13 positive regulation of DNA-binding transcription factor activity GO:0051091 9.91 TNF IL6 IL5 IL1B IL10
14 B cell differentiation GO:0030183 9.9 IL4 IL10 IFNA1
15 negative regulation of interleukin-6 production GO:0032715 9.9 TNF TLR9 IL10
16 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.89 TNF TLR9 IL1B
17 response to glucocorticoid GO:0051384 9.89 TNF IL6 IL10
18 positive regulation of interferon-gamma production GO:0032729 9.89 TNF TLR9 IL1B
19 positive regulation of T cell proliferation GO:0042102 9.88 IL6 IL4 IL1B
20 positive regulation of interleukin-1 beta production GO:0032731 9.88 TNF IL6 IFNG
21 positive regulation of cytokine production GO:0001819 9.88 TNF IL10 IFNG
22 positive regulation of interleukin-8 production GO:0032757 9.88 TNF TLR9 IL6 IL1B
23 humoral immune response GO:0006959 9.87 TNF IL6 IFNG IFNA1
24 positive regulation of phagocytosis GO:0050766 9.85 TNF IL1B IFNG
25 positive regulation of nitric oxide biosynthetic process GO:0045429 9.85 TNF IL1B IFNG
26 positive regulation of interleukin-6 production GO:0032755 9.85 TNF TLR9 IL6 IL1B IFNG
27 positive regulation of B cell proliferation GO:0030890 9.84 TLR9 IL5 IL4
28 positive regulation of interleukin-10 production GO:0032733 9.84 TLR9 IL6 IL4
29 microglial cell activation GO:0001774 9.83 TNF IL4 IFNG
30 positive regulation of chemokine production GO:0032722 9.83 TNF TLR9 IL6 IFNG
31 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.8 TNF IL6 IL4 IL3 IFNG
32 positive regulation of glial cell proliferation GO:0060252 9.79 TNF IL6 IL1B
33 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.78 TNF IL1B IFNG
34 positive regulation of JAK-STAT cascade GO:0046427 9.78 TNF IL6 IL5 IL10
35 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.77 TNF IL1B IL10
36 inflammatory response GO:0006954 9.76 TNF TLR9 IL6 IL5 IL1B CXCL8
37 positive regulation of neuroinflammatory response GO:0150078 9.75 TNF IL6 IL1B
38 positive regulation of MHC class II biosynthetic process GO:0045348 9.73 IL4 IL10 IFNG
39 negative regulation of neurogenesis GO:0050768 9.73 TNF IL6 IL1B CCL11
40 regulation of establishment of endothelial barrier GO:1903140 9.72 TNF IL1B
41 response to molecule of bacterial origin GO:0002237 9.72 TLR9 IL10 CXCL8
42 endothelial cell apoptotic process GO:0072577 9.71 TNF IL10
43 negative regulation of lipid storage GO:0010888 9.71 TNF IL6 CRP
44 positive regulation of mononuclear cell migration GO:0071677 9.7 TNF IL4
45 negative regulation of cytokine production involved in immune response GO:0002719 9.7 TNF IL10
46 immune response GO:0006955 9.7 TNF TLR9 IL6 IL5 IL4 IL3
47 positive regulation of cellular respiration GO:1901857 9.69 IL4 IFNG
48 neuroinflammatory response GO:0150076 9.69 IL4 IFNG
49 type 2 immune response GO:0042092 9.69 IL4 IL10
50 positive regulation of fever generation GO:0031622 9.68 TNF IL1B

Molecular functions related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.36 TNF IL6 IL5 IL4 IL3 IL1B
2 growth factor activity GO:0008083 9.35 IL6 IL5 IL4 IL3 IL10

Sources for Gastroenteritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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