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MCID: GST045
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Gastroenteritis

Categories: Gastrointestinal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Gastroenteritis

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MalaCards integrated aliases for Gastroenteritis:

Name: Gastroenteritis 12 74 54 42 15 17 71
Cholera Morbus 12 71
Infectious Colitis, Enteritis and Gastroenteritis 12

Classifications:

MalaCards categories:
Anatomical: Gastrointestinal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:2326
NCIt 49 C34632
SNOMED-CT 67 25374005
ICD10 32 K52.9
UMLS 71 C0017160 C0206151
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Summaries for Gastroenteritis

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MedlinePlus : 42 Have you ever had the "stomach flu?" What you probably had was gastroenteritis - not a type of flu at all. Gastroenteritis is an inflammation of the lining of the intestines caused by a virus, bacteria, or parasites. Viral gastroenteritis is the second most common illness in the U.S. The cause is often a norovirus infection. It spreads through contaminated food or water or by contact with an infected person. The best prevention is frequent hand washing. Symptoms of gastroenteritis include diarrhea, abdominal pain, vomiting, headache, fever, and chills. Most people recover with no treatment. The most common problem with gastroenteritis is dehydration. This happens if you do not drink enough fluids to replace what you lose through vomiting and diarrhea. Dehydration is most common in babies, young children, older adults, and people with weak immune systems. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Gastroenteritis, also known as cholera morbus, is related to eosinophilic gastroenteritis and cryptosporidiosis, and has symptoms including fever, pruritus and nausea and vomiting. An important gene associated with Gastroenteritis is LACTB (Lactamase Beta), and among its related pathways/superpathways are Innate Immune System and PEDF Induced Signaling. The drugs Scopolamine and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include testes, colon and kidney, and related phenotypes are cardiovascular system and hematopoietic system

Disease Ontology : 12 A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. Chemicals and drugs also cause gastroenteritis. The symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen.

Wikipedia : 74 Gastroenteritis, also known as infectious diarrhea and gastro, is inflammation of the gastrointestinal... more...

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Related Diseases for Gastroenteritis

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Diseases related to Gastroenteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1090)
# Related Disease Score Top Affiliating Genes
1 eosinophilic gastroenteritis 34.9 RNASE3 IL5 IL4 EPX CCL11 ALB
2 cryptosporidiosis 33.4 IFNG CCL11 CAT
3 shigellosis 33.3 TNF IL1B IL10 CXCL8
4 listeriosis 33.2 TNF IL6 IL1B IL10
5 influenza 33.1 TNF IL6 IL1B IFNG IFNA1 CXCL8
6 dysentery 33.1 TNF IL6 IL1B IL10 CXCL8 CRP
7 ileitis 32.2 TNF IL6 IL10
8 diarrhea 32.1 TNF IL6 IL5 IL1B IL10 IFNG
9 colitis 31.8 TNF TLR9 IL6 IL4 IL1B IL10
10 intussusception 31.6 IL6 CRP ALB
11 cholera 31.5 TNF IL6 IL4 IL1B CXCL8
12 lactose intolerance 31.4 IL10 CRP ANPEP ALB
13 intestinal obstruction 31.4 TNF IL6 CRP ALB
14 hypereosinophilic syndrome 31.4 RNASE3 IL5 IL4 IL10 IFNG IFNA1
15 gastritis 31.4 TNF IL6 IL1B IL10 CXCL8 CAT
16 esophagitis, eosinophilic, 1 31.3 RNASE3 IL5 IL4 EPX CCL11
17 irritable bowel syndrome 31.3 TNF TLR9 IL6 IL1B IL10 CXCL8
18 salmonellosis 31.3 TNF TLR9 LACTB IL6 IL1B IL10
19 vasculitis 31.3 TNF IL6 IL10 CRP
20 chemical colitis 31.2 TNF IL6 IL1B IL10
21 pancreatitis 31.2 TNF IL6 IL1B IL10 CRP ALB
22 esophagitis 31.2 TNF IL6 IL5 IL4 IL1B IL10
23 eosinophilic gastritis 31.2 IL5 EPX CCL11
24 ige responsiveness, atopic 31.1 RNASE3 IL5 IL4 IL10 IFNG
25 intestinal perforation 31.1 TNF IL6 CRP ALB
26 toxic megacolon 31.1 TNF CRP ALB
27 acute pancreatitis 31.1 TNF IL6 IL1B IL10 CXCL8 CRP
28 gastric ulcer 31.0 TNF IL6 IL1B CXCL8
29 ileus 31.0 TNF IL6 IL1B IL10 IFNG CRP
30 cholecystitis 31.0 RNASE3 CAT ANPEP ALB
31 peritonitis 31.0 TNF IL6 IL4 IL1B IL10 IFNG
32 duodenal ulcer 31.0 TNF IL6 IL1B IL10 CXCL8 CAT
33 typhoid fever 31.0 TNF IL6 IL1B IFNG CRP ALB
34 hyperuricemia 31.0 CXCL8 CRP CAT ALB
35 iron deficiency anemia 31.0 TNF IL6 CRP CAT
36 reactive arthritis 31.0 TNF IL6 IL1B IL10 IFNG CXCL8
37 coronavirus infectious disease 31.0 TNF IL6 IFNA1 CXCL8 CRP ANPEP
38 encephalitis 31.0 TNF IL6 IL4 IL1B IL10 IFNA1
39 duodenitis 30.9 TNF CRP ALB
40 bacterial infectious disease 30.9 TNF TLR9 IL6 IL1B IL10 IFNG
41 graft-versus-host disease 30.9 TNF IL6 IL1B IL10 IFNG
42 amebiasis 30.9 TNF IL4 IL1B CXCL8 ALB
43 intestinal disease 30.9 TNF IL6 IL1B IL10 CXCL8 CRP
44 appendicitis 30.9 TNF IL6 IL1B IL10 IFNG CXCL8
45 milk allergy 30.9 TNF RNASE3 IL5 IL4 IL10
46 disseminated intravascular coagulation 30.9 TNF IL6 IL10 CRP
47 perinatal necrotizing enterocolitis 30.8 TNF TLR9 IL6 IL1B IL10 CXCL8
48 purpura 30.8 TNF IL6 IL4 IL10 IFNG CRP
49 erysipelas 30.8 TNF IL6 IL1B CRP CAT
50 cystitis 30.8 TNF IL6 IL4 CXCL8 CRP

Graphical network of the top 20 diseases related to Gastroenteritis:



Diseases related to Gastroenteritis
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Symptoms & Phenotypes for Gastroenteritis

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UMLS symptoms related to Gastroenteritis:


fever, pruritus, nausea and vomiting, abdominal pain, constipation, diarrhea, abdominal cramps, icterus, signs and symptoms, digestive, dyspepsia, heartburn, gastrointestinal gas, gastric irritation

MGI Mouse Phenotypes related to Gastroenteritis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.07 ALB ANPEP CRP IFNG IL10 IL1B
2 hematopoietic system MP:0005397 10 ANPEP CCL11 EPX IFNG IL10 IL1B
3 digestive/alimentary MP:0005381 9.97 ALB FUT2 IFNG IL10 IL4 IL5
4 homeostasis/metabolism MP:0005376 9.97 ALB CAT CRP EPX IFNG IL10
5 immune system MP:0005387 9.8 ALB ANPEP CCL11 CRP EPX FUT2
6 neoplasm MP:0002006 9.23 ALB CAT IFNG IL10 IL1B IL5
Sources

Drugs & Therapeutics for Gastroenteritis

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Drugs for Gastroenteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 222)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Scopolamine Approved, Investigational Phase 4 6533-68-2, 51-34-3 5184
2
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4 437-38-7 3345
3
Ceftriaxone Approved Phase 4 73384-59-5 5361919 5479530
4
Ondansetron Approved Phase 4 99614-02-5 4595
5
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
6
Sodium citrate Approved, Investigational Phase 4 68-04-2
7
Dimenhydrinate Approved Phase 4 523-87-5 441281
8
Loperamide Approved Phase 4 53179-11-6 3955
9
Metoclopramide Approved, Investigational Phase 4 364-62-5 4168
10
tannic acid Approved Phase 4 1401-55-4
11
Benzocaine Approved, Investigational Phase 4 94-09-7, 1994-09-7 2337
12
Sorbitol Approved Phase 4 50-70-4 5780
13
Calcium carbonate Approved, Investigational Phase 4 471-34-1
14
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
15 Hydrotalcite Approved, Experimental, Investigational Phase 4 12304-65-3
16
Sucralfate Approved Phase 4 54182-58-0
17
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
18
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
19
Dexlansoprazole Approved, Investigational Phase 4 103577-45-3, 138530-94-6 9578005
20
Citric acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
21
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
22
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
23
Racecadotril Investigational Phase 4 81110-73-8
24 Cholinergic Agents Phase 4
25 Parasympatholytics Phase 4
26 Muscarinic Antagonists Phase 4
27 Cholinergic Antagonists Phase 4
28 Anesthetics Phase 4
29 Bromides Phase 4
30 Mydriatics Phase 4
31 Butylscopolammonium Bromide Phase 4
32 Acidophilus Phase 4
33 Anti-Anxiety Agents Phase 4
34 Psychotropic Drugs Phase 4
35 Antipsychotic Agents Phase 4
36 Bifidobacterium Phase 4
37 Dopamine Agents Phase 4
38 Dopamine Antagonists Phase 4
39 Citrate Phase 4
40 Antidiarrheals Phase 4
41 Emetics Phase 4
42
protease inhibitors Phase 4
43 HIV Protease Inhibitors Phase 4
44 Dextrans Phase 4
45 Vitamins Phase 4
46 Antioxidants Phase 4
47 Retinol palmitate Phase 4
48 retinol Phase 4
49 Pharmaceutical Solutions Phase 4
50 Gastrointestinal Agents Phase 4

Interventional clinical trials:

(show top 50) (show all 366)
# Name Status NCT ID Phase Drugs
1 Assessment of Analgesic Efficacy and Safety of Intravenous Hyoscine-N-Butylbromide in Patients With Abdominal Colic Associated With Acute Gastroenteritis; a Randomized, Double-blind, Placebo Controlled Study Unknown status NCT02508142 Phase 4 Hyoscine-N-Butylbromide
2 The Role of Short-course Ceftriaxone Therapy in the Treatment of Severe Nontyphoidal Salmonella Enterocolitis Unknown status NCT01278017 Phase 4 ceftriaxone
3 Cross-reactive Immunity Elicited by Oral and Parenteral Typhoid Vaccines Against Non-typhoid Salmonellae Unknown status NCT02121145 Phase 4
4 Impact of Four Patient Information Leaflets (PIL) on Patient Behaviour : a Randomised Controlled Trial in Primary Care. Completed NCT01398696 Phase 4
5 Efficacy and Safety of Probiotics in the Treatment of Acute Gastroenteritis in Children Completed NCT03539913 Phase 4
6 Impact of Systematic Infants Vaccination Against Rotavirus on Gastroenteritis Hospitalization: a Prospective Study in Brest District, France. Completed NCT00740935 Phase 4
7 Rapid Diagnostics and Probiotic Therapy for Paediatric Acute Gastroenteritis - a Randomized, Factorial, Controlled, Placebo-controlled, Pilot Trial Completed NCT02025452 Phase 4
8 Comparison of Clinical Efficacy of Enteroadsorbent Polymethylsiloxane vs Probiotic Lactobacillus Reuteri in the Treatment of Rotaviral Gastroenteritis in Infants and Toddlers. Completed NCT04116307 Phase 4
9 Bacillus Clausii in the Treatment of Acute Community-acquired Diarrhea Among Latin American Children (cadiLAc) Completed NCT02169817 Phase 4 Bacillus clausii;Oral Rehydration Therapy
10 Emergency Department Rapid Intravenous Rehydration (RIVR) for Pediatric Gastroenteritis: A Randomized Controlled Trial Completed NCT00392145 Phase 4 Standard IV rehydration;Rapid intravenous rehydration (RIVR)
11 A Randomized Double-blind Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Moderate Vomiting Due to Acute Gastroenteritis Completed NCT00124787 Phase 4 Dimenhydrinate;Placebo
12 Immunogenicity of the Human Rotavirus Vaccine (Rotarixâ„¢) at Varying Schedules, Doses, and Ages in Rural Ghana Completed NCT01575197 Phase 4
13 Immunogenicity, Reactogenicity and Safety Study to Evaluate Two Doses of the Lyophilised Formulation of the Human Rotavirus (HRV) Vaccine When Administered to Healthy Korean Infants Previously Uninfected With HRV Completed NCT00969228 Phase 4
14 Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis: A Double Blind Randomized, Placebo- Controlled Trial Completed NCT01657032 Phase 4
15 Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis: Randomized, Double-Blind Controlled Trial Completed NCT01467570 Phase 4
16 The Treatment Effect of Bio-Three on Children With Enteritis Due to Salmonella or Rotavirus or Any Unknown Reason Completed NCT01480947 Phase 4 Bio-three
17 Ondansetron Vs Metoclopramide in the Treatment of Vomiting in Gastroenteritis Patients: A Randomized Controlled Trial Completed NCT01165866 Phase 4 Treatment 1. Metoclopramide;Treatment 2 Ondansetron
18 The Immunogenicity of Rotavirus Vaccine Under Different Age Schedules and the Impact of Withholding Breast Feeding Around the Time of Vaccination on the Immunogenicity of Rotarix Vaccine Completed NCT01199874 Phase 4
19 Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children: A Randomized Double-blind Trial Completed NCT01564290 Phase 4 Placebo probiotic
20 Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants Under Six Months. Completed NCT01571856 Phase 4 Zinc Sulfate
21 Ondansetron Administration to Children With Gastroenteritis, Vomiting and SOME Dehydration in Emergency Departments in Pakistan Completed NCT01870648 Phase 4 Ondansetron;Placebo
22 Ondansetron Administration to WELL Children With Gastroenteritis Associated Vomiting in Emergency Departments in Pakistan Completed NCT01870635 Phase 4 Ondansetron;Placebo
23 An Open-label, Pilot Study to Compare the Safety and Immunogenicity of an Alternate Dosing Schedule (2-5 Weeks, 2 Months, and 4 Months) for Pentavalent Rotavirus Vaccine (RotaTeq) to the Standard Recommended Schedule (2, 4, and 6 Months) Completed NCT01960725 Phase 4
24 The Effect of a Probiotic and/or Prebiotic on the Duration of Diarrhea and Length of Hospital Stay in Children With Acute Diarrhea: Prospective, Double Blind, Randomized Controlled Trial Completed NCT01927094 Phase 4
25 Efficacy of Racecadotril in the Management of Acute Watery Diarrhea in Children Completed NCT01577043 Phase 4 Racecadotril
26 Introduction of an Oral Live Human Rotavirus (Rotarix) Vaccine in Matlab Completed NCT00737503 Phase 4
27 Lactobacillus Reuteri Reduces Pulmonary Exacerbations and Upper Respiratory Tract Infections in CF Patients With Mild-to-moderate Lung Disease. LR Administration Might Have a Beneficial Effect on the Disease Course of Cystic Fibrosis. Completed NCT01737983 Phase 4
28 The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease: a Placebo-controlled Randomized Trial Completed NCT02010762 Phase 4 Vitamin D;Placebo
29 Safety and Immunogenicity of Sequential Rotavirus Vaccine Schedules With RotaTeq® and Rotarix® Completed NCT01266850 Phase 4
30 A Comparison of Effectiveness of Oral Sucrolfate, Alginate and Hydrotalcide in Dispeptic Pain Treatment: Randomized Trial Completed NCT03635372 Phase 4 Alginate;Sucralfate;Hydrotalcite
31 International Multicenter, Double-blind, Randomized, Parallel Group Placebo-Controlled Clinical Trial of Efficacy and Safety of Ergoferon in the Treatment of Viral Intestinal Infections in Children Completed NCT03039699 Phase 4 Ergoferon;Placebo
32 Manipulation of Visceral Hypersensitivity With Probiotic Bacteria in Irritable Bowel Syndrome Completed NCT01139736 Phase 4
33 The ORVAC Trial: A Phase IV, Double-blind, Randomised, Placebo-controlled Clinical Trial of a Third Scheduled Dose of RV1 Rotavirus Vaccine in Australian Indigenous Infants to Improve Protection Against Gastroenteritis Recruiting NCT02941107 Phase 4 Rotarix (RV1);Placebo
34 Proton Pump Inhibitor (PPI) Response in Eosinophilic Esophagitis Assessed by Transnasal Endoscopy (TNE) Recruiting NCT04149470 Phase 4 Omeprazole 20mg BID
35 The Effectiveness of Pleuran in Treatment of Acute Gastroenteritis in Children- a Randomized, Placebo-controlled, Double-blind Trial Recruiting NCT03988257 Phase 4
36 Effectiveness of Vonoprazan vs Omeprazole as Empiric Therapy for Gastroesophageal Reflux Disease (GERD) Patients Without Alarm Features in a Primary Care Setting: A Pragmatic, Randomized, Single Blind Study Recruiting NCT04028466 Phase 4 Vonoprazan;Omeprazole
37 A Double-Blind, Randomized, Comparative Efficacy and Safety Trial of Intravenous Solutions for the Treatment of Moderate to Severe Dehydration in Children With Acute Gastroenteritis Terminated NCT01234883 Phase 4 multiple electrolyte solution;saline
38 The Frequency of Eosinophilic Esophagitis in Patients With Heartburn That is Refractory to Proton Pump Inhibitors Terminated NCT01404832 Phase 4 Treat with lansoprazole 30 mg BID for 2 weeks, endoscopic examination with esophageal biopsy for patients with persistent symptoms
39 Phase Three Clinical Trials of Trivalent Rotavirus Genetic Reassortment Vaccine Unknown status NCT01738074 Phase 3
40 Phase II Double Blind Placebo-controled Randomized Comparative Multicentered Study of Efficacy and Safety of Filtrum-STI, 0,4g Tablets (Produced by AVVA RUS) in Children With Viral Gastroenteritis Unknown status NCT01113346 Phase 2, Phase 3 Filtrum-STI (lignin hydrolytic);Placebo
41 A Phase III, Randomized, Double Blind, Placebo Controlled Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E, Against Severe Rotavirus Gastroenteritis in Infants Unknown status NCT01305109 Phase 3
42 Comparison of Efficacy of Ondansetron Versus Metoclopramide for Vomiting in Children With Acute Gastroenteritis: Randomized Controlled Clinical Trial Unknown status NCT02619201 Phase 3 Ondansetron;metoclopramide
43 Impact of Emergency Department Probiotic (LGG) Treatment of Pediatric Gastroenteritis Completed NCT01773967 Phase 2, Phase 3 LGG;micro-crystalline cellulose
44 Randomized, Placebo-Controlled, Phase 3 Trial of BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis (The GUARD Study) Completed NCT02246439 Phase 3 RHB-102;Placebo Oral Tablet
45 A Multicenter, Double-Blind, Randomized Study to Compare The Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00392574 Phase 3 Prulifloxacin;Placebo
46 A Phase III Randomized, Placebo-controlled Clinical Trial to Study the Efficacy and Safety of V260 in Healthy Infants in Japan Completed NCT00718237 Phase 3
47 A Multicenter, Double-Blind, Randomized Study to Compare the Safety and Efficacy of Prulifloxacin Versus Placebo in the Treatment of Acute Gastroenteritis in Adult Travelers Completed NCT00448422 Phase 3 prulifloxacin
48 The Implementation of a Gastroenteritis Education Program Completed NCT00311831 Phase 3
49 the Effectiveness of Echinacea, Propolis and Vitamin C in the Prevention of Respiratory Tract Infections and Gastroenteritis in Preschool Age Children: a Prospective Study Completed NCT00231218 Phase 3 dietary supplement--echinacea, propolis, and vitamin c
50 A Double-blind, Randomized, Controlled, Multicenter Study to Evaluate the Safety, Tolerability, and Immunogenicity of a New Formulation of RotaTeqâ„¢ Completed NCT01600092 Phase 3

Search NIH Clinical Center for Gastroenteritis

Inferred drug relations via UMLS 71 / NDF-RT 50 :


ERYTHROMYCIN PWDR
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Genetic Tests for Gastroenteritis

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Anatomical Context for Gastroenteritis

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MalaCards organs/tissues related to Gastroenteritis:

40
Testes, Colon, Kidney, Small Intestine, Liver, Breast, T Cells
Sources

Publications for Gastroenteritis

About this section

Articles related to Gastroenteritis:

(show top 50) (show all 19274)
# Title Authors PMID Year
1
Epidemiology and HBGA-susceptibility investigation of a G9P[8] rotavirus outbreak in a school in Lechang, China. 61 42
32253617 2020
2
Prevalence and molecular characterization of parechovirus A in children with acute gastroenteritis in Shenzhen, 2016-2018. 42 61
32296995 2020
3
Molecular characteristics of Clostridium difficile in children with acute gastroenteritis from Zhejiang. 42 61
32404060 2020
4
[Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus]. 61 54
19634766 2009
5
Porcine aminopeptidase N is a functional receptor for the PEDV coronavirus. 61 54
17467767 2007
6
Nosocomial outbreak of pediatric gastroenteritis caused by CTX-M-14-type extended-spectrum beta-lactamase-producing strains of Salmonella enterica serovar London. 54 61
16000495 2005
7
Identification of a putative cellular receptor 150 kDa polypeptide for porcine epidemic diarrhea virus in porcine enterocytes. 61 54
14685034 2003
8
[A study of serum mitochondrial enzymes(mCK, mAST, mMDH) in rotavirus and adenovirus gastroenteritis in pediatric patients]. 54 61
11769565 2001
9
Interspecies aminopeptidase-N chimeras reveal species-specific receptor recognition by canine coronavirus, feline infectious peritonitis virus, and transmissible gastroenteritis virus. 61 54
8985407 1997
10
Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct from the enzymatic site. 61 54
7913510 1994
11
Rapid and specific detection of the thermostable direct haemolysin gene in Vibrio parahaemolyticus by the polymerase chain reaction. 61 54
8126441 1993
12
Biochemical and immunologic characterization of serum biotinidase in partial biotinidase deficiency. 61 54
1561012 1992
13
Prevalence, antibiotic resistance and genotypes of Campylobacter jejuni and Campylobacter coli isolated from chickens in Irbid governorate, Jordan. 61
32445835 2020
14
Norovirus infection and HBGA host genetic susceptibility in a birth community-cohort, Rio de Janeiro, Brazil. 61
32165242 2020
15
A trial of lacosamide for benign convulsions with gastroenteritis. 61
32279898 2020
16
Variability in lag-duration of Campylobacter spp. during enrichment after cold and oxidative stress and its impact on growth kinetics and reliable detection. 61
32517946 2020
17
Heavy metal and antibiotic co-resistance in Vibrio parahaemolyticus isolated from shellfish. 61
32510388 2020
18
Immunogenicity and protective potency of Norovirus GII.17 virus-like particle-based vaccine. 61
32088791 2020
19
Three cases of fulminant cellulitis caused by non-O1, non-O139 Vibrio cholerae in Southern Finland. 61
32324089 2020
20
Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. 61
31773359 2020
21
Experimental evaluation of survival of Vibrio parahaemolyticus in fertilized cold-water sediment. 61
32086873 2020
22
Biotechnologically produced fucosylated oligosaccharides inhibit the binding of human noroviruses to their natural receptors. 61
32387450 2020
23
Aichivirus With Acute Gastroenteritis in Iran. 61
32097244 2020
24
Detection of antibiotic resistance and virulence genes of Vibrio strains isolated from ready-to-eat shrimps in Delta and Edo States, Nigeria. 61
31977129 2020
25
MDCT in the Setting of Suspected Colonic Diverticulitis: Prevalence and Diagnostic Yield for Diverticulitis and Alternative Diagnoses. 61
32319796 2020
26
Molecular and Epidemiologic Analysis of Diarrheal Pathogens in Children With Acute Gastroenteritis in Bangladesh During 2014-2019. 61
32187137 2020
27
Impact of Routine Rotavirus Vaccination in Germany: Evaluation Five Years After Its Introduction. 61
32187139 2020
28
Gastroenteritis exposure and the risk of schizophrenia onset: A systematic review and meta-analysis. 61
32417692 2020
29
The Role of Human Coronavirus Infection in Pediatric Acute Gastroenteritis. 61
32433226 2020
30
Viral gastroenteritis in hospitalized patients: Evaluation of immunochromatographic methods for rapid detection in stool samples. 61
32454428 2020
31
ABO blood group-associated susceptibility to norovirus infection: A systematic review and meta-analysis. 61
32092482 2020
32
Whole genome sequence analysis of cell culture-adapted rotavirus A strains from chicken. 61
32147474 2020
33
Spatial and temporal profiles of enteric viruses in the coastal waters of Tokyo Bay during and after a series of rainfall events. 61
32335450 2020
34
Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank. 61
31427754 2020
35
Multiple ulcerations and perforation in the small intestine after steroid treatment in eosinophilic granulomatosis with polyangiitis: a case report and literature review. 61
32151788 2020
36
Use of a probiotic mixture containing Bifidobacterium animalis subsp. lactis BB-12 and Enterococcus faecium L3 as prophylaxis to reduce the incidence of acute gastroenteritis and upper respiratory tract infections in children. 61
32506882 2020
37
Molecular characterization of rotaviruses obtained from patients with rotavirus-associated encephalitis/encephalopathy. 61
32511783 2020
38
Exploring the genetic determinants underlying the differential production of an inducible chromosomal cephalosporinase - BlaB in Yersinia enterocolitica biotypes 1A, 1B, 2 and 4. 61
32576927 2020
39
Infectious Norovirus Is Chronically Shed by Immunocompromised Pediatric Hosts. 61
32516960 2020
40
The association between ambient temperature and clinical visits for inflammation-related diseases in rural areas in China. 61
32105966 2020
41
Room Costs for Common Pediatric Hospitalizations and Cost-Reducing Quality Initiatives. 61
32366609 2020
42
Pre-vaccine rotavirus surveillance in Buenos Aires, Argentina. Characterization of an emergent G1P[8] strain associated to fatal cases in 2014. 61
31931256 2020
43
Fondness for sugars of enteric viruses confronts them with human glycans genetic diversity. 61
31760489 2020
44
An outbreak of Shiga toxin-producing Escherichia coli O157:H7 linked to a mud-based obstacle course, England, August 2018. 61
32564515 2020
45
Phenotypic and Genotypic Characterization of Virulence Factors and Susceptibility to Antibiotics in Salmonella Infantis Strains Isolated from Chicken Meat: First Findings in Chile. 61
32570768 2020
46
Questing functions and structures of hypothetical proteins from Campylobacter jejuni: a computer-aided approach. 61
32458979 2020
47
Recent advances in human norovirus research and implications for candidate vaccines. 61
32500763 2020
48
Guanylate-binding protein 2 orchestrates innate immune responses against murine norovirus and is antagonized by the viral protein NS7. 61
32354743 2020
49
Unrevealed genetic diversity of GII Norovirus in the swine population of North East Italy. 61
32513947 2020
50
Antibiotic Activity of a Paraphaeosphaeria sporulosa-Produced Diketopiperazine against Salmonella enterica. 61
32531985 2020
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Variations for Gastroenteritis

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Expression for Gastroenteritis

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Search GEO for disease gene expression data for Gastroenteritis.
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Pathways for Gastroenteritis

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Pathways related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 74)
# Super pathways Score Top Affiliating Genes
1
Innate Immune System 65
Show member pathways
 14.09 TNF TLR9 RNASE3 IL6 IL5 IL4
2
PEDF Induced Signaling 63
Show member pathways
 13.77 TNF IL6 IL5 IL4 IL1B IL10
3
TGF-Beta Pathway 63
Show member pathways
 13.64 TNF IL6 IL5 IL4 IL1B IL10
4
Akt Signaling 63
Show member pathways
 13.51 TNF TLR9 IL6 IL5 IL4 IL1B
5
Cytokine Signaling in Immune system 65
Show member pathways
 13.48 TNF IL6 IL5 IL4 IL1B IL10
6
PAK Pathway 63
Show member pathways
 13.39 TNF IL6 IL5 IL4 IL1B IL10
7
Toll-like Receptor Signaling Pathway 36 1
Show member pathways
 13.17 TNF TLR9 IL6 IL1B IL10 IFNG
8
Measles 36
Show member pathways
 12.94 TNF TLR9 IL6 IL1B IFNG IFNA1
9
Pathways in cancer 36
12.93 IL6 IL5 IL4 IFNG IFNA1 CXCL8
10
Herpes simplex virus 1 infection 36
12.89 TNF TLR9 IL6 IL1B IFNG IFNA1
11
Toll-Like receptor Signaling Pathways 64
Show member pathways
 12.83 TNF TLR9 IL6 IL1B IFNA1 CXCL8
12
Th17 cell differentiation 36
Show member pathways
 12.74 TNF IL6 IL5 IL4 IL1B IL10
13
T cell receptor signaling pathway 36
Show member pathways
 12.71 TNF TLR9 IL6 IL5 IL4 IL1B
14
NF-kappaB Signaling 4
12.7 TNF TLR9 IL4 IL1B IL10 IFNG
15
Immune response IL-23 signaling pathway 22
Show member pathways
 12.66 TNF IL6 IL1B IL10 IFNG
16
JAK-STAT signaling pathway 36
Show member pathways
 12.57 IL6 IL5 IL4 IL10 IFNG IFNA1
17
Allograft rejection 1 36
Show member pathways
 12.48 TNF RNASE3 IL6 IL5 IL4 IL1B
18
IL-17 Family Signaling Pathways 64
Show member pathways
 12.45 TNF IL6 IL5 IL4 IL1B IFNG
19
Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions 64
Show member pathways
 12.44 TNF IL6 IL10 CXCL8 CCL11
20
Folate Metabolism 1
Show member pathways
 12.43 TNF IL6 IL4 IL1B IFNG CRP
21
Toll Comparative Pathway 63
Show member pathways
 12.42 TNF IL6 IL1B IFNG CXCL8
22
Salmonella infection (KEGG) 36
12.42 TNF TLR9 IL6 IL1B CXCL8
23
Toxoplasmosis 36
Show member pathways
 12.38 TNF IL4 IL1B IL10 IFNG
24
NOD-like receptor signaling pathway 36
12.36 TNF IL6 IL1B IFNA1 CXCL8
25
Tuberculosis 36
12.36 TNF TLR9 IL6 IL1B IL10 IFNG
26
Pathogenic Escherichia coli infection 36
12.33 TNF IL6 IL1B CXCL8
27
Diseases associated with the TLR signaling cascade 65
Show member pathways
 12.33 TNF TLR9 IL6 CXCL8
28
C-type lectin receptor signaling pathway 36
Show member pathways
 12.33 TNF TLR9 IL6 IL1B IL10
29
Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways 1
12.3 TNF IL6 IL1B IL10 CXCL8
30
Immune response IFN alpha/beta signaling pathway 22
Show member pathways
 12.3 TNF IL6 IL5 IL4 IL1B IL10
31
Necroptosis 36
Show member pathways
 12.27 TNF IL1B IFNG IFNA1
32
Colorectal Cancer Metastasis 63
12.26 TNF TLR9 IL6 IFNG
33
Bacterial infections in CF airways 22
Show member pathways
 12.19 TNF TLR9 IL6 IL4 IL1B IFNG
34
Spinal Cord Injury 1
12.17 TNF IL6 IL4 IL1B IFNG CXCL8
35
Yersinia infection 36
12.15 TNF IL6 IL1B IL10 CXCL8
36
Hematopoietic Stem Cells and Lineage-specific Markers 64
12.13 TNF IL6 IL5 IL4 IL10 IFNG
37
IL27-mediated signaling events 1
Show member pathways
 12.1 TNF TLR9 IL6 IL1B IL10 IFNG
38
Interleukin-4 and 13 signaling 65
12.08 TNF IL6 IL4 IL1B IL10 CXCL8
39
Amoebiasis 36
12.07 TNF IL6 IL1B IL10 IFNG CXCL8
40
Senescence and Autophagy in Cancer 1
12.05 IL6 IL1B IFNG CXCL8
41
Hematopoietic cell lineage 36
12.05 TNF IL6 IL5 IL4 IL1B ANPEP
42
Rheumatoid arthritis 36
12.03 TNF IL6 IL1B IFNG CXCL8
43
AGE-RAGE signaling pathway in diabetic complications 36
12.02 TNF IL6 IL1B CXCL8
44
Th17 Differentiation 64
Show member pathways
 12.02 TLR9 IL6 IL4 IL1B IFNG
45
Glucocorticoid receptor regulatory network 1
11.96 IL6 IL5 IL4 IFNG CXCL8
46
Innate Lymphoid Cells Differentiation 64
11.93 TNF IL5 IL4 IL1B IL10 IFNG
47
Pertussis 36
11.92 TNF IL6 IL1B IL10 CXCL8
48
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 1
Show member pathways
 11.91 TNF IL5 IL4 IFNG CXCL8
49
Dendritic Cells Developmental Lineage Pathway 64
11.88 TNF TLR9 IL6 IL1B IL10 IFNG
50
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.82 TNF IL6 IL1B IFNG CXCL8
Sources

GO Terms for Gastroenteritis

About this section

Cellular components related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.86 TNF TLR9 RNASE3 IL6 IL5 IL4
2 extracellular space GO:0005615 9.53 TNF RNASE3 IL6 IL5 IL4 IL1B

Biological processes related to Gastroenteritis according to GeneCards Suite gene sharing:

(show top 50) (show all 62)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 10.35 TLR9 IL6 IL5 IL4 IL1B IL10
2 positive regulation of transcription, DNA-templated GO:0045893 10.16 TNF IL6 IL5 IL4 IL1B IL10
3 defense response to bacterium GO:0042742 10.03 TNF TLR9 RNASE3 IL10 EPX
4 defense response to virus GO:0051607 10.01 TLR9 IL6 IFNG IFNA1
5 positive regulation of gene expression GO:0010628 10 TNF TLR9 IL6 IL4 IL1B IFNG
6 defense response GO:0006952 9.98 TNF IFNA1 EPX CXCL8
7 cellular response to lipopolysaccharide GO:0071222 9.97 TNF IL6 IL1B IL10 CXCL8
8 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.96 TNF TLR9 IL6 IL1B CAT
9 defense response to Gram-positive bacterium GO:0050830 9.94 TNF RNASE3 IL6 CRP
10 positive regulation of inflammatory response GO:0050729 9.92 TNF TLR9 IL1B IFNG
11 neutrophil chemotaxis GO:0030593 9.91 IL1B CXCL8 CCL11
12 B cell differentiation GO:0030183 9.9 IL4 IL10 IFNA1
13 regulation of insulin secretion GO:0050796 9.9 TNF IL1B IFNG
14 response to glucocorticoid GO:0051384 9.9 TNF IL6 IL10
15 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.89 TNF TLR9 IL1B
16 positive regulation of T cell proliferation GO:0042102 9.89 IL6 IL4 IL1B
17 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.89 TNF IL6 IL4 IFNG
18 positive regulation of phagocytosis GO:0050766 9.86 TNF IL1B IFNG
19 inflammatory response GO:0006954 9.86 TNF TLR9 IL6 IL5 IL1B CXCL8
20 positive regulation of nitric oxide biosynthetic process GO:0045429 9.85 TNF IL1B IFNG
21 positive regulation of interleukin-6 secretion GO:2000778 9.85 TNF IL1B IFNG
22 humoral immune response GO:0006959 9.85 TNF IL6 IFNG IFNA1
23 positive regulation of B cell proliferation GO:0030890 9.84 TLR9 IL5 IL4
24 negative regulation of interleukin-6 production GO:0032715 9.84 TNF TLR9 IL10
25 positive regulation of cytokine secretion GO:0050715 9.83 TNF IL10 IFNG
26 positive regulation of interleukin-6 production GO:0032755 9.83 TNF TLR9 IL6 IL1B
27 positive regulation of DNA-binding transcription factor activity GO:0051091 9.83 TNF IL6 IL5 IL1B IL10
28 microglial cell activation GO:0001774 9.82 TNF IL4 IFNG
29 positive regulation of interleukin-8 production GO:0032757 9.82 TNF TLR9 IL1B
30 positive regulation of chemokine production GO:0032722 9.79 TNF TLR9 IL6
31 positive regulation of glial cell proliferation GO:0060252 9.78 TNF IL6 IL1B
32 astrocyte activation GO:0048143 9.77 TNF IL1B IFNG
33 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.76 TNF IL1B IFNG
34 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.75 TNF IL1B IL10
35 negative regulation of amyloid-beta clearance GO:1900222 9.73 TNF IFNG
36 negative regulation of interleukin-8 production GO:0032717 9.73 TLR9 IL10
37 positive regulation of interleukin-1 beta biosynthetic process GO:0050725 9.72 TNF IFNG
38 regulation of establishment of endothelial barrier GO:1903140 9.72 TNF IL1B
39 endothelial cell apoptotic process GO:0072577 9.72 TNF IL10
40 positive regulation of mononuclear cell migration GO:0071677 9.71 TNF IL4
41 type 2 immune response GO:0042092 9.71 IL4 IL10
42 positive regulation of neuroinflammatory response GO:0150078 9.71 TNF IL6 IL1B
43 positive regulation of JAK-STAT cascade GO:0046427 9.71 TNF IL6 IL5 IL10
44 negative regulation of cytokine production involved in immune response GO:0002719 9.7 TNF IL10
45 positive regulation of cellular respiration GO:1901857 9.7 IL4 IFNG
46 neuroinflammatory response GO:0150076 9.7 IL4 IFNG
47 positive regulation of fever generation GO:0031622 9.69 TNF IL1B
48 negative regulation of cytokine secretion involved in immune response GO:0002740 9.69 TNF IL10
49 response to molecule of bacterial origin GO:0002237 9.69 TLR9 IL10 CXCL8
50 regulation of isotype switching GO:0045191 9.67 IL4 IL10

Molecular functions related to Gastroenteritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.32 TNF IL6 IL5 IL4 IL1B IL10
2 growth factor activity GO:0008083 9.26 IL6 IL5 IL4 IL10
Sources

Sources for Gastroenteritis

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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