Gastrointestinal Anthrax disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: GST046 MIFTS: 24	Gastrointestinal Anthrax Categories: Gastrointestinal diseases, Infectious diseases
Genes Related diseases Publications Pathways Expand all tables

Sources

Aliases & Classifications for Gastrointestinal Anthrax

MalaCards integrated aliases for Gastrointestinal Anthrax:

Name: Gastrointestinal Anthrax ¹² ⁴⁴ ¹⁵ ⁷⁰ ³²

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ³²

Certain infectious and parasitic diseases

Certain zoonotic bacterial diseases

Anthrax

Gastrointestinal anthrax

External Ids:

Disease Ontology ¹² DOID:13386

ICD9CM ³⁴ 022.2

MeSH ⁴⁴ C571911

SNOMED-CT ⁶⁷ 186302005

ICD10 ³² A22.2

UMLS ⁷⁰ C0152945

Sources

Summaries for Gastrointestinal Anthrax

Disease Ontology : ¹² An anthrax disease that results in infection located in mucosa of gastrointestinal tract, has material basis in Bacillus anthracis, which is transmitted by ingestion of anthrax-infected meat. The infection has symptom lesions, has symptom vomiting of blood, has symptom severe diarrhea, has symptom loss of appetite.

MalaCards based summary : Gastrointestinal Anthrax is related to oropharyngeal anthrax and anthrax disease. An important gene associated with Gastrointestinal Anthrax is ANTXR2 (ANTXR Cell Adhesion Molecule 2), and among its related pathways/superpathways are NOD-like receptor signaling pathway and Uptake and actions of bacterial toxins. Related phenotypes are immune system and mortality/aging

Sources

Related Diseases for Gastrointestinal Anthrax

Diseases related to Gastrointestinal Anthrax via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)

#	Related Disease	Score	Top Affiliating Genes
1	oropharyngeal anthrax	31.2	EXOC6 ARAP3 ANTXR2 ANTXR1
2	anthrax disease	30.7	PRDX1 NLRP1 FURIN ANTXR2 ANTXR1
3	cutaneous anthrax	29.4	PRDX1 FURIN ANTXR2 ANTXR1
4	hydrops, lactic acidosis, and sideroblastic anemia	10.1	ANTXR2 ANTXR1
5	winchester syndrome	10.1	ANTXR2 ANTXR1
6	gingival hypertrophy	10.0	ANTXR2 ANTXR1
7	hyaline fibromatosis syndrome	10.0	ANTXR2 ANTXR1
8	disease by infectious agent	9.9
9	bacterial infectious disease	9.9
10	toxic shock syndrome	9.9
11	gastroenteritis	9.9
12	pneumonia	9.9
13	inhalation anthrax	9.7	PRDX1 FURIN ANTXR2 ANTXR1
14	familial febrile seizures	9.6	INHA ABR

Graphical network of the top 20 diseases related to Gastrointestinal Anthrax:

Sources

Symptoms & Phenotypes for Gastrointestinal Anthrax

MGI Mouse Phenotypes related to Gastrointestinal Anthrax:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	immune system	MP:0005387	9.5	ANTXR1 ANTXR2 EXOC6 FURIN INHA NLRP1
2	mortality/aging	MP:0010768	9.23	ABR ANTXR1 ANTXR2 ARAP3 EXOC6 FURIN

Sources

Drugs & Therapeutics for Gastrointestinal Anthrax

Search Clinical Trials , NIH Clinical Center for Gastrointestinal Anthrax

Cochrane evidence based reviews: gastrointestinal anthrax

Sources

Genetic Tests for Gastrointestinal Anthrax

Sources

Anatomical Context for Gastrointestinal Anthrax

Sources

Publications for Gastrointestinal Anthrax

Articles related to Gastrointestinal Anthrax:

(show all 39)

#	Title	Authors	PMID	Year
1	Common garlic (Allium sativum L.) has potent Anti-Bacillus anthracis activity. ⁶¹	Kaur R...Singh S	32853741	2021
2	Outbreak of Anthrax Associated with Handling and Eating Meat from a Cow, Uganda, 2018. ⁶¹	Kisaakye E...Zhu BP	33219644	2020
3	TaqMan Assays for Simultaneous Detection of Bacillus anthracis and Bacillus cereus biovar anthracis. ⁶¹	Zincke D...Blackburn JK	33371332	2020
4	Outbreak of gastrointestinal anthrax following eating beef of suspicious origin: Isingiro District, Uganda, 2017. ⁶¹	Nakanwagi M...Zhu BP	32106229	2020
5	Gastrointestinal and cutaneous anthrax: Case series. ⁶¹	Ozer V...Gunduz A	31073544	2019
6	Musical Instrument-Associated Health Issues and Their Management. ⁶¹	Okoshi K...Tomizawa Y	28931767	2017
7	A case report of inhalation anthrax acquired naturally. ⁶¹	Azarkar Z...Bidaki MZ	26939756	2016
8	The Saccharomyces boulardii CNCM I-745 strain shows protective effects against the B. anthracis LT toxin. ⁶¹	Pontier-Bres R...Czerucka D	26529015	2015
9	Passive Immunotherapy Protects against Enteric Invasion and Lethal Sepsis in a Murine Model of Gastrointestinal Anthrax. ⁶¹	Huang B...Frucht DM	26426050	2015
10	Rapid Detection of Bacillus anthracis in Complex Food Matrices Using Phage-Mediated Bioluminescence. ⁶¹	Sharp NJ...Schofield DA	25951391	2015
11	New insights into gastrointestinal anthrax infection. ⁶¹	Owen JL...Mohamadzadeh M	25577136	2015
12	Anthrax: A disease of biowarfare and public health importance. ⁶¹	Goel AK	25610847	2015
13	A case of fatal gastrointestinal anthrax in north eastern iran. ⁶¹	Hashemi SA...Ghafouri M	25918652	2015
14	Gastrointestinal anthrax: clinical experience in 5 cases. ⁶¹	Maddah G...Katebi M	24009958	2013
15	A New Murine Model for Gastrointestinal Anthrax Infection. ⁶¹	Xie T...Frucht DM	23825096	2013
16	In vivo murine and in vitro M-like cell models of gastrointestinal anthrax. ⁶¹	Tonry JH...Chung MC	23108317	2013
17	Complete genome sequence of Bacillus anthracis H9401, an isolate from a Korean patient with anthrax. ⁶¹	Chun JH...Rhie GE	22815438	2012
18	Anthrax: an update. ⁶¹	Kamal SM...Ahad MA	23569822	2011
19	Rapid sporulation of Bacillus anthracis in a high iron, glucose-free medium. ⁶¹	Purohit M...Rest RF	20621133	2010
20	Gastrointestinal anthrax after an animal-hide drumming event - New Hampshire and Massachusetts, 2009. ⁶¹	Centers for Disease Control and Prevention (CDC)	20651643	2010
21	[The return of anthrax. From bioterrorism to the zoonotic cluster of Sciacca district]. ⁶¹	Scarlata F...Titone L	20610930	2010
22	Two cases of gastrointestinal anthrax with an unusual presentation from Kermanshah (western Iran). ⁶¹	Hatami H...Mansoori F	20187673	2010
23	A case of pneumonia caused by Bacillus anthracis secondary to gastrointestinal anthrax. ⁶¹	Meric M...Hosten T	19201638	2009
24	Human anthrax in Turkey from 1990 to 2007. ⁶¹	Doganay M...Metan G	18945187	2009
25	Cutaneous anthrax in the Artibonite Valley of Haiti: 1992-2002. ⁶¹	Peck RN...Fitzgerald DW	17984330	2007
26	Inhalational, gastrointestinal, and cutaneous anthrax in children: a systematic review of cases: 1900 to 2005. ⁶¹	Bravata DM...Owens DK	17768291	2007
27	Primary involvement of pharynx and peyer's patch in inhalational and intestinal anthrax. ⁶¹	Glomski IJ...Goossens PL	17542645	2007
28	Three rare cases of anthrax arising from the same source. ⁶¹	Babamahmoodi F...Ashrafi GH	16442628	2006
29	Pediatric anthrax: implications for bioterrorism preparedness. ⁶¹	Bravata DM...Owens DK	17764208	2006
30	Anthrax kills wild chimpanzees in a tropical rainforest. ⁶¹	Leendertz FH...Pauli G	15269768	2004
31	Gastrointestinal anthrax: review of the literature. ⁶¹	Beatty ME...Sobel J	14609791	2003
32	When bioterrorism strikes: diagnosis and management of inhalational anthrax. ⁶¹	Shafazand S	14505276	2003
33	Endemic gastrointestinal anthrax in 1960s Lebanon: clinical manifestations and surgical findings. ⁶¹	Kanafani ZA...Kanj SS	12737733	2003
34	Anthrax of the gastrointestinal tract. ⁶¹	Sirisanthana T...Brown AE	12095428	2002
35	[Anthrax--the past, present and future]. ⁶¹	Madle-Samardzija N...Sevic S	12070927	2002
36	Anthrax. ⁶¹	Datta KK...Singh J	11876121	2002
37	Clinical aspects, diagnosis and treatment of anthrax ⁶¹	Friedlander AM	10475974	1999
38	[Anthrax meningitis]. ⁶¹	Durst UN...Spiegel MV	3764392	1986
39	An outbreak of human gastrointestinal anthrax. ⁶¹	Ndyabahinduka DG...Gaifuba JK	6545639	1984

Sources

Genes for Gastrointestinal Anthrax

Genes related to Gastrointestinal Anthrax (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	ANTXR2	ANTXR Cell Adhesion Molecule 2	Protein Coding	7.28	DISEASES inferred ¹⁵
2	ANTXR1	ANTXR Cell Adhesion Molecule 1	Protein Coding	6.93	DISEASES inferred ¹⁵
3	FURIN	Furin, Paired Basic Amino Acid Cleaving Enzyme	Protein Coding	6.05	DISEASES inferred ¹⁵
4	ARAP3	ArfGAP With RhoGAP Domain, Ankyrin Repeat And PH Domain 3	Protein Coding	5.39	DISEASES inferred ¹⁵
5	EXOC6	Exocyst Complex Component 6	Protein Coding	5.06	DISEASES inferred ¹⁵
6	PRDX1	Peroxiredoxin 1	Protein Coding	5.03	DISEASES inferred ¹⁵
7	ABR	ABR Activator Of RhoGEF And GTPase	Protein Coding	5.03	DISEASES inferred ¹⁵
8	INHA	Inhibin Subunit Alpha	Protein Coding	5.01	DISEASES inferred ¹⁵
9	NLRP1	NLR Family Pyrin Domain Containing 1	Protein Coding	4.92	DISEASES inferred ¹⁵
10	ILVBL	IlvB Acetolactate Synthase Like	Protein Coding	4.82	DISEASES inferred ¹⁵

Sources

Variations for Gastrointestinal Anthrax

Sources

Expression for Gastrointestinal Anthrax

Search GEO for disease gene expression data for Gastrointestinal Anthrax.

Sources

Pathways for Gastrointestinal Anthrax

Pathways related to Gastrointestinal Anthrax according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NOD-like receptor signaling pathway ³⁶	11.59	NLRP1 ANTXR2 ANTXR1
2	Uptake and actions of bacterial toxins ⁶⁵ Show member pathways Intestinal infectious diseases ⁶⁵ Neurotoxicity of clostridium toxins ⁶⁵ Toxicity of botulinum toxin type A (BoNT/A) ⁶⁵ Toxicity of botulinum toxin type B (BoNT/B) ⁶⁵ Toxicity of botulinum toxin type C (BoNT/C) ⁶⁵ Toxicity of botulinum toxin type E (BoNT/E) ⁶⁵ Toxicity of botulinum toxin type G (BoNT/G) ⁶⁵ Toxicity of tetanus toxin (TeNT) ⁶⁵ Uptake and function of anthrax toxins ⁶⁵ Uptake and function of diphtheria toxin ⁶⁵	11.03	FURIN ANTXR2 ANTXR1
3	Regulation of RhoA activity ¹	10.92	ARAP3 ABR
4	Cellular roles of Anthrax toxin ¹	10.14	NLRP1 ANTXR2 ANTXR1

Sources

GO Terms for Gastrointestinal Anthrax

Cellular components related to Gastrointestinal Anthrax according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell projection	GO:0042995	9.26	EXOC6 ARAP3 ANTXR1 ABR
2	endosome membrane	GO:0010008	8.8	FURIN ANTXR2 ANTXR1

Biological processes related to Gastrointestinal Anthrax according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	toxin transport	GO:1901998	8.62	ANTXR2 ANTXR1

Sources

Sources for Gastrointestinal Anthrax

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Apr-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia