MCID: GST091
MIFTS: 22

Gastrointestinal Neuroendocrine Benign Tumor

Categories: Cancer diseases, Gastrointestinal diseases, Neuronal diseases

Aliases & Classifications for Gastrointestinal Neuroendocrine Benign Tumor

MalaCards integrated aliases for Gastrointestinal Neuroendocrine Benign Tumor:

Name: Gastrointestinal Neuroendocrine Benign Tumor 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:4148
NCIt 50 C27721
UMLS 72 C1333799

Summaries for Gastrointestinal Neuroendocrine Benign Tumor

MalaCards based summary : Gastrointestinal Neuroendocrine Benign Tumor is related to ureter small cell carcinoma and primary hepatic neuroendocrine carcinoma. An important gene associated with Gastrointestinal Neuroendocrine Benign Tumor is CHGA (Chromogranin A), and among its related pathways/superpathways are Secretion of Hydrochloric Acid in Parietal Cells and Gastric acid production. Related phenotypes are homeostasis/metabolism and digestive/alimentary

Related Diseases for Gastrointestinal Neuroendocrine Benign Tumor

Diseases in the Gastrointestinal Neuroendocrine Tumor family:

Gastrointestinal Neuroendocrine Benign Tumor

Diseases related to Gastrointestinal Neuroendocrine Benign Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 ureter small cell carcinoma 10.8 SYP CHGA
2 primary hepatic neuroendocrine carcinoma 10.8 SYP CHGA
3 cellular ependymoma 10.8 SYP CHGA
4 peritoneal serous adenocarcinoma 10.8 SYP CHGA
5 chordoid meningioma 10.8 SYP CHGA
6 lung combined type small cell carcinoma 10.8 SYP NCAM1
7 olfactory groove meningioma 10.7 SYP CHGA
8 pituitary carcinoma 10.7 SST CHGA
9 intracranial primitive neuroectodermal tumor 10.7 ENO2 CHGA
10 carotid body cancer 10.7 SYP ENO2
11 glucagonoma 10.7 SST CHGA
12 mongolian spot 10.7 SST ENO2
13 hypoganglionosis 10.7 SYP NCAM1
14 malignant sertoli cell tumor 10.7 SYP ENO2
15 epithelioid malignant peripheral nerve sheath tumor 10.7 ENO2 CHGA
16 multiple mucosal neuroma 10.7 NCAM1 ENO2
17 hormone producing pituitary cancer 10.7 SST MEN1
18 lung meningioma 10.7 NCAM1 ENO2
19 sinonasal undifferentiated carcinoma 10.7 SYP ENO2
20 retroperitoneal neuroblastoma 10.7 SST ENO2
21 lung oat cell carcinoma 10.7 ENO2 CHGA
22 duodenal somatostatinoma 10.7 SST ENO2
23 papillary tumor of the pineal region 10.7 SYP ENO2
24 choriocarcinoma of ovary 10.7 NCAM1 ENO2
25 middle ear adenoma 10.7 SYP ENO2
26 gastrointestinal neuroendocrine tumor 10.7 SYP SST CHGA
27 sensory organ benign neoplasm 10.7 SYP ENO2
28 pancreatoblastoma 10.6 SYP SST CHGA
29 esophageal neuroendocrine tumor 10.6 SYP NCAM1 CHGA
30 ovarian large-cell neuroendocrine carcinoma 10.6 SYP NCAM1 CHGA
31 binswanger's disease 10.6 SYP SST CHGA
32 clear cell ependymoma 10.6 SYP ENO2
33 cerebellum cancer 10.6 SYP ENO2
34 renal adenoma 10.6 NCAM1 B3GAT1
35 cystadenoma 10.6 SYP MUC6 CHGA
36 insulinoma 10.6 SST MEN1 CHGA
37 central nervous system primitive neuroectodermal neoplasm 10.6 SYP ENO2
38 conventional angiosarcoma 10.6 SYP NCAM1 CHGA
39 pancreatic serous cystadenoma 10.6 SYP NCAM1 CHGA
40 cerebral neuroblastoma 10.6 SYP ENO2
41 microcystic adenoma 10.6 MUC6 ENO2
42 somatostatinoma 10.6 SST ENO2 CHGA
43 pancreatic cystadenoma 10.6 SST MEN1 CHGA
44 pancreatic endocrine carcinoma 10.6 SYP SST NCAM1
45 tanycytic ependymoma 10.6 SYP MEN1 CHGA
46 vaginal tubulovillous adenoma 10.6 CHGA CDX2
47 vaginal adenoma 10.6 CHGA CDX2
48 acute thyroiditis 10.6 ENO2 CHGA
49 vaginal benign neoplasm 10.6 CHGA CDX2
50 astroblastoma 10.6 SYP ENO2

Graphical network of the top 20 diseases related to Gastrointestinal Neuroendocrine Benign Tumor:



Diseases related to Gastrointestinal Neuroendocrine Benign Tumor

Symptoms & Phenotypes for Gastrointestinal Neuroendocrine Benign Tumor

MGI Mouse Phenotypes related to Gastrointestinal Neuroendocrine Benign Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 ATP12A ATP4A CACNA1A CBLIF CDX2 CHGA
2 digestive/alimentary MP:0005381 9.7 ATP12A ATP4A CDX2 GAST MEN1 MUC5AC
3 mortality/aging MP:0010768 9.4 ATP4A B3GAT1 CACNA1A CBLIF CDX2 CHGA

Drugs & Therapeutics for Gastrointestinal Neuroendocrine Benign Tumor

Search Clinical Trials , NIH Clinical Center for Gastrointestinal Neuroendocrine Benign Tumor

Genetic Tests for Gastrointestinal Neuroendocrine Benign Tumor

Anatomical Context for Gastrointestinal Neuroendocrine Benign Tumor

Publications for Gastrointestinal Neuroendocrine Benign Tumor

Variations for Gastrointestinal Neuroendocrine Benign Tumor

Expression for Gastrointestinal Neuroendocrine Benign Tumor

Search GEO for disease gene expression data for Gastrointestinal Neuroendocrine Benign Tumor.

Pathways for Gastrointestinal Neuroendocrine Benign Tumor

Pathways related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 9.65 GAST ATP4A
2 9.64 MUC6 GAST CBLIF

GO Terms for Gastrointestinal Neuroendocrine Benign Tumor

Cellular components related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.28 SST SPINK5 NCAM1 MUC6 MUC5AC GAST

Biological processes related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular sodium ion homeostasis GO:0006883 9.26 ATP4A ATP12A
2 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP4A ATP12A
3 sodium ion export across plasma membrane GO:0036376 8.96 ATP4A ATP12A
4 cellular potassium ion homeostasis GO:0030007 8.62 ATP4A ATP12A

Molecular functions related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 four-way junction DNA binding GO:0000400 9.16 MEN1 GEN1
2 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP4A ATP12A
3 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP4A ATP12A

Sources for Gastrointestinal Neuroendocrine Benign Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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