MCID: GST091
MIFTS: 25

Gastrointestinal Neuroendocrine Benign Tumor

Categories: Cancer diseases, Gastrointestinal diseases, Neuronal diseases

Aliases & Classifications for Gastrointestinal Neuroendocrine Benign Tumor

MalaCards integrated aliases for Gastrointestinal Neuroendocrine Benign Tumor:

Name: Gastrointestinal Neuroendocrine Benign Tumor 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:4148
NCIt 50 C27721
UMLS 73 C1333799

Summaries for Gastrointestinal Neuroendocrine Benign Tumor

MalaCards based summary : Gastrointestinal Neuroendocrine Benign Tumor is related to insulinoma and adenoma of the pancreas. An important gene associated with Gastrointestinal Neuroendocrine Benign Tumor is CHGA (Chromogranin A), and among its related pathways/superpathways are Salivary secretion and Gastric acid production. Affiliated tissues include lung, skin and pituitary, and related phenotypes are digestive/alimentary and homeostasis/metabolism

Related Diseases for Gastrointestinal Neuroendocrine Benign Tumor

Diseases in the Gastrointestinal Neuroendocrine Tumor family:

Gastrointestinal Neuroendocrine Benign Tumor

Diseases related to Gastrointestinal Neuroendocrine Benign Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 insulinoma 10.2 CHGA SST
2 adenoma of the pancreas 10.2 CHGA SST
3 gastrointestinal neuroendocrine tumor 10.2 CHGA SST
4 pituitary carcinoma 10.2 CHGA SST
5 glucagonoma 10.2 CHGA SST
6 pancreatoblastoma 10.2 CHGA SST
7 carcinoid tumors, intestinal 10.2 CHGA SST
8 somatostatinoma 10.2 CHGA SST
9 binswanger's disease 10.1 CHGA SST
10 carcinoid syndrome 10.1 CHGA SST
11 pancreatic cystadenoma 10.1 CHGA SST
12 fungal esophagitis 10.1 ATP12A ATP4A
13 malignant pheochromocytoma 10.1 CHGA SST
14 diclofenac allergy 10.1 ATP12A ATP4A
15 neonatal candidiasis 10.1 ATP12A ATP4A
16 photoallergic dermatitis 10.1 ATP12A ATP4A
17 squamous papillomatosis 10.1 ATP12A ATP4A
18 toxic megacolon 10.1 ATP12A ATP4A
19 aspiration pneumonitis 10.1 ATP12A ATP4A
20 esophageal candidiasis 10.1 ATP12A ATP4A
21 acute laryngitis 10.1 ATP12A ATP4A
22 laryngitis 10.1 ATP12A ATP4A
23 rumination disorder 10.1 ATP12A ATP4A
24 active peptic ulcer disease 10.1 ATP12A ATP4A
25 congenital disorder of deglycosylation 10.1 ATP12A ATP4A
26 bladder calculus 10.1 ATP12A ATP4A
27 ischemic neuropathy 10.1 ATP12A ATP4A
28 bile reflux 10.1 ATP12A ATP4A
29 capillary disease 10.1 ATP12A ATP4A
30 peptic esophagitis 10.1 ATP12A ATP4A
31 dyskinesia of esophagus 10.1 ATP12A ATP4A
32 hernia, hiatus 10.1 ATP12A ATP4A
33 anismus 10.1 ATP12A ATP4A
34 postsurgical hypothyroidism 10.1 ATP12A ATP4A
35 esophageal atresia/tracheoesophageal fistula 10.1 ATP12A ATP4A
36 clostridium difficile colitis 10.1 ATP12A ATP4A
37 endocrine organ benign neoplasm 10.1 CHGA SST
38 diarrhea 1, secretory chloride, congenital 10.1 ATP12A ATP4A
39 microscopic colitis 10.1 ATP12A ATP4A
40 laryngeal tuberculosis 10.1 ATP12A ATP4A
41 chronic laryngitis 10.1 ATP12A ATP4A
42 eosinophilic gastritis 10.1 ATP12A ATP4A
43 esophagus adenocarcinoma 10.1 ATP12A ATP4A
44 chronic intestinal vascular insufficiency 10.1 ATP12A ATP4A
45 polyposis, skin pigmentation, alopecia, and fingernail changes 10.1 ATP12A ATP4A
46 jejunoileitis 10.1 ATP12A ATP4A
47 superior mesenteric artery syndrome 10.1 ATP12A ATP4A
48 gastric lymphoma 10.1 ATP12A ATP4A
49 lower urinary tract calculus 10.1 ATP12A ATP4A
50 myopathy, x-linked, with excessive autophagy 10.1 ATP12A ATP4A

Graphical network of the top 20 diseases related to Gastrointestinal Neuroendocrine Benign Tumor:



Diseases related to Gastrointestinal Neuroendocrine Benign Tumor

Symptoms & Phenotypes for Gastrointestinal Neuroendocrine Benign Tumor

MGI Mouse Phenotypes related to Gastrointestinal Neuroendocrine Benign Tumor:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.35 ATP12A ATP4A GAST SST TP63
2 homeostasis/metabolism MP:0005376 9.17 ATP12A ATP4A CBLIF CHGA GAST SST

Drugs & Therapeutics for Gastrointestinal Neuroendocrine Benign Tumor

Search Clinical Trials , NIH Clinical Center for Gastrointestinal Neuroendocrine Benign Tumor

Genetic Tests for Gastrointestinal Neuroendocrine Benign Tumor

Anatomical Context for Gastrointestinal Neuroendocrine Benign Tumor

MalaCards organs/tissues related to Gastrointestinal Neuroendocrine Benign Tumor:

41
Lung, Skin, Pituitary, Pancreas, Thyroid

Publications for Gastrointestinal Neuroendocrine Benign Tumor

Variations for Gastrointestinal Neuroendocrine Benign Tumor

Expression for Gastrointestinal Neuroendocrine Benign Tumor

Search GEO for disease gene expression data for Gastrointestinal Neuroendocrine Benign Tumor.

Pathways for Gastrointestinal Neuroendocrine Benign Tumor

Pathways related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.55 ATP4A GAST SST
2 9.8 CBLIF GAST
3 9.32 ATP4A GAST

GO Terms for Gastrointestinal Neuroendocrine Benign Tumor

Cellular components related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.02 ATP4A CBLIF CHGA GAST SST

Biological processes related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 potassium ion import across plasma membrane GO:1990573 9.4 ATP12A ATP4A
2 potassium ion import GO:0010107 9.37 ATP12A ATP4A
3 ATP hydrolysis coupled proton transport GO:0015991 9.32 ATP12A ATP4A
4 cellular sodium ion homeostasis GO:0006883 9.26 ATP12A ATP4A
5 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP12A ATP4A
6 cellular potassium ion homeostasis GO:0030007 8.96 ATP12A ATP4A
7 sodium ion export across plasma membrane GO:0036376 8.62 ATP12A ATP4A

Molecular functions related to Gastrointestinal Neuroendocrine Benign Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 potassium:proton exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Gastrointestinal Neuroendocrine Benign Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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