MCID: GST051
MIFTS: 32

Gastrointestinal Tuberculosis

Categories: Endocrine diseases, Gastrointestinal diseases, Infectious diseases

Aliases & Classifications for Gastrointestinal Tuberculosis

MalaCards integrated aliases for Gastrointestinal Tuberculosis:

Name: Gastrointestinal Tuberculosis 12 15 17
Tuberculosis of Intestines, Peritoneum and Mesenteric Glands 12 33
Tuberculosis, Gastrointestinal 44 72
Tuberculosis of Intestines, Peritoneum, and Mesenteric Glands 12
Tuberculosis of Gastrointestinal Tract 12

Classifications:



External Ids:

Disease Ontology 12 DOID:404
MeSH 44 D014385
ICD10 33 A18.3
UMLS 72 C0041312

Summaries for Gastrointestinal Tuberculosis

Disease Ontology : 12 An abdominal tuberculosis that results in infection located in gastrointestinal tract. The infection has symptom abdominal pain, has symptom weight loss, has symptom fever, has symptom anorexia, has symptom change in bowel habits, has symptom nausea, and has symptom vomiting.

MalaCards based summary : Gastrointestinal Tuberculosis, also known as tuberculosis of intestines, peritoneum and mesenteric glands, is related to intestinal tuberculosis and pulmonary tuberculosis, and has symptoms including fever, vomiting and abdominal pain. An important gene associated with Gastrointestinal Tuberculosis is TBP (TATA-Box Binding Protein), and among its related pathways/superpathways are Selenium Micronutrient Network and Glucocorticoid receptor regulatory network. The drug Antitubercular Agents has been mentioned in the context of this disorder. Affiliated tissues include colon, testes and lymph node, and related phenotypes are cardiovascular system and homeostasis/metabolism

Related Diseases for Gastrointestinal Tuberculosis

Diseases related to Gastrointestinal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 129)
# Related Disease Score Top Affiliating Genes
1 intestinal tuberculosis 31.6 CRP CD53 ABCB8
2 pulmonary tuberculosis 30.7 IFNG ADA
3 miliary tuberculosis 29.9 IFNG ADA
4 tuberculous peritonitis 29.8 TBP IFNG CRP ALB ADA
5 extrapulmonary tuberculosis 29.6 TBP IFNG ADA
6 appendicitis 29.6 CRP ALB
7 dysentery 29.4 CRP ALB
8 intestinal disease 29.0 CRP ALB
9 peritonitis 28.9 CRP ALB ADA
10 gastrointestinal system disease 28.6 IFNG CRP ALB
11 abdominal tuberculosis 28.0 TBP CRP ALB ADA ABCB8
12 oral tuberculosis 11.2
13 hepatic tuberculosis 11.2
14 esophageal tuberculosis 11.2
15 mycobacterium tuberculosis 1 10.5
16 constrictive pericarditis 10.3 ALB ADA
17 cryptococcal meningitis 10.2 IFNG ADA
18 crohn's disease 10.1
19 chronic graft versus host disease 10.1 IFNG ALB
20 strongyloidiasis 10.1 IFNG CD53
21 chronic inflammatory demyelinating polyradiculoneuropathy 10.1 IFNG ALB
22 polyradiculoneuropathy 10.1 IFNG ALB
23 fascioliasis 10.1 IFNG ALB
24 hypersplenism 10.1 IFNG ALB
25 hepatitis e 10.1 IFNG ALB
26 testicular disease 10.1 IFNG ALB
27 hepatitis a 10.1 IFNG ALB
28 salmonellosis 10.0 IFNG ALB
29 dengue hemorrhagic fever 10.0 IFNG ALB
30 pleural empyema 10.0 CRP ADA
31 filariasis 10.0 IFNG ALB
32 upper respiratory tract disease 10.0 IFNG ALB
33 food allergy 10.0 IFNG ALB
34 visceral leishmaniasis 10.0 IFNG ALB
35 pericardial effusion 10.0 CRP ADA
36 inflammatory bowel disease 10.0
37 bacterial pneumonia 10.0 CRP ADA
38 schistosomiasis 10.0 IFNG ALB
39 pyuria 9.9 CRP ALB
40 decubitus ulcer 9.9 CRP ALB
41 intestinal perforation 9.9
42 pericardium disease 9.9 CRP ALB
43 hypersensitivity reaction type iii disease 9.9 CRP ALB
44 peptic ulcer perforation 9.9 CRP ALB
45 acute cystitis 9.9 CRP ALB
46 prediabetes syndrome 9.9 CRP ALB
47 analbuminemia 9.9 CRP ALB
48 acute pyelonephritis 9.9 CRP ALB
49 pyelonephritis 9.9 CRP ALB
50 pericardial tuberculosis 9.9 TBP IFNG ADA

Graphical network of the top 20 diseases related to Gastrointestinal Tuberculosis:



Diseases related to Gastrointestinal Tuberculosis

Symptoms & Phenotypes for Gastrointestinal Tuberculosis

Symptoms:

12
  • fever
  • vomiting
  • abdominal pain
  • weight loss
  • anorexia
  • nausea
  • change in bowel habits

MGI Mouse Phenotypes related to Gastrointestinal Tuberculosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.35 ABCB8 ADA CRP IFNG TBP
2 homeostasis/metabolism MP:0005376 9.1 ABCB8 ADA ALB CRP IFNG TBP

Drugs & Therapeutics for Gastrointestinal Tuberculosis

Drugs for Gastrointestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Multi-centric Study on Treatment of Abdominal Tuberculosis (Intestinal or Peritoneal): A Randomized Controlled Trial to Compare the 6 Months of Cat I Treatment With 9 Months of Cat I Treatment (Extension for 3 Months) in Abdominal Tuberculosis Under the Revised National Tuberculosis Control Program Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months

Search NIH Clinical Center for Gastrointestinal Tuberculosis

Cochrane evidence based reviews: tuberculosis, gastrointestinal

Genetic Tests for Gastrointestinal Tuberculosis

Anatomical Context for Gastrointestinal Tuberculosis

MalaCards organs/tissues related to Gastrointestinal Tuberculosis:

41
Colon, Testes, Lymph Node

The Foundational Model of Anatomy Ontology organs/tissues related to Gastrointestinal Tuberculosis:

19
Gastrointestinal Tract

Publications for Gastrointestinal Tuberculosis

Articles related to Gastrointestinal Tuberculosis:

(show top 50) (show all 155)
# Title Authors PMID Year
1
Duodenal tuberculosis; uncommon cause of gastric outlet obstruction. 38
31228078 2019
2
Atypical serious hematochezia and rare imaging feature in gastrointestinal tuberculosis. 38
30232704 2019
3
Multiplex Polymerase Chain Reaction for diagnosis of gastrointestinal tuberculosis. 38
30834338 2019
4
Diagnosis of abdominal tuberculosis: lessons learned over 30 years: pectoral assay. 38
31338118 2019
5
Gastric Tuberculosis Presenting as a Subepithelial Mass: A Rare Cause of Gastrointestinal Bleeding. 38
30642149 2018
6
Impact of Mycobacterium tuberculosis complex lineages as a determinant of disease phenotypes from an immigrant rich moderate tuberculosis burden country. 38
30587190 2018
7
Primary Appendicular Malignancy Presenting as Abdominal Wall Abscess with Secondary Tuberculosis Infection: an Interesting Case Report. 38
30538401 2018
8
Anorectal tuberculosis as a chronic rectal mass mimicking rectal prolapse in a child-a case report. 38
30568795 2018
9
Acquired zinc deficiency in a renal transplant recipient with gastrointestinal tuberculosis responding promptly to oral correction. 38
30381519 2018
10
Gastrointestinal Tuberculosis Presenting as Malnutrition and Distal Colonic Bowel Obstruction. 38
29682364 2018
11
[Gastric tuberculosis in an elderly patient:a case report]. 38
30416160 2018
12
Tuberculous Enteritis Presenting as Acute Appendicitis and Perirectal Abscess. 38
29560012 2018
13
Clinical and laboratory features of intestinal tuberculosis. 38
29559804 2018
14
Perforated tuberculous appendicitis: a rare case report. 38
29881313 2018
15
Gastrointestinal tuberculosis following renal transplantation accompanied with septic shock and acute respiratory distress syndrome: a survival case presentation. 38
29179699 2017
16
A Rare Thermophilic Bug in Complicated Diverticular Abscess. 38
29118685 2017
17
[Gastrointestinal tuberculosis as a cause of massive gastrointestinal bleeding in a patient with HIV infection]. 38
29165521 2017
18
Gastric outlet obstruction: an unusual case of primary duodenal tuberculosis. 38
28343151 2017
19
Kaleidoscopic View of Bowel Tuberculosis on Multi- Detector Computed Tomography (CT) Enterography - A Novel Technique Unfolding an Archaic Disease. 38
29657645 2017
20
Ileocaecal and transverse colonic tuberculosis mimicking colonic malignancy - A case report. 38
28486175 2017
21
Gastrointestinal Tuberculosis. 38
28084201 2016
22
Clinico-Pathological Profile and Surgical Outcome of Patients of Gastrointestinal Tuberculosis Undergoing Laparotomy. 38
28044950 2016
23
A retrospective cohort study of 756 cases of abdominal tuberculosis: Two decades single centre experience. 38
27998497 2016
24
Role of mitochondrial oxidative stress on lymphocyte homeostasis in patients diagnosed with extra-pulmonary tuberculosis. 38
26431927 2016
25
The Role of PCR in Diagnosis of a Rare Appendicular Tuberculosis and Mini Literature Review. 38
27123348 2016
26
[Asymptomatic Synchronous Tuberculosis Involving Stomach and Small Bowel in Immunocompetent Patient]. 38
26691192 2015
27
Intermittent Directly Observed Therapy for Abdominal Tuberculosis: A Multicenter Randomized Controlled Trial Comparing 6 Months Versus 9 Months of Therapy. 38
25969531 2015
28
Management of Severe Gastrointestinal Tuberculosis with Injectable Antituberculous Drugs. 38
26543395 2015
29
Intestinal Flora Modification of Arthritis Pattern in Spondyloarthropathy. 38
26267718 2015
30
Radiological findings in duodenal tuberculosis: a 15-year experience. 38
25416003 2015
31
Abdominal tuberculosis mimicking Crohn's disease's exacerbation: A clinical, diagnostic and surgical dilemma. A case report. 38
25528041 2015
32
Non-healing gastro-duodenal ulcer: A rare presentation of primary abdominal tuberculosis. 38
25506841 2015
33
Tuberculosis infection causing intestinal perforations in 2 patients with systemic lupus erythematosus. 38
25036568 2014
34
Tubercular duodenal, jejunal and ileocecal stricture in a patient. 38
24334467 2013
35
Esophageal tuberculosis presenting with hematemesis. 38
24255751 2013
36
Development of miliary tuberculosis under infliximab in a patient with spondyloarthritis and suspected Crohn's disease. 38
24122379 2013
37
Multiplex PCR for rapid diagnosis of gastrointestinal tuberculosis. 38
23853431 2013
38
Primary duodenal tuberculosis presenting as gastric-outlet obstruction: Its diagnosis. 38
23860052 2013
39
A case series of gastrointestinal tuberculosis in renal transplant patients. 38
24558621 2013
40
Gastrointestinal tuberculosis is not associated with proton pump inhibitors: a retrospective cohort study. 38
23345949 2013
41
[Gastrointestinal tuberculosis: a deceptive disease]. 38
23739601 2013
42
Primary tuberculous appendicitis presented with caecal perforation: a case report. 38
23043927 2012
43
Duodenal tuberculosis presenting as gatric outlet obstruction. 38
24960738 2012
44
Diagnosis and treatment strategies of tuberculous intestinal perforations: a case series. 38
22293329 2012
45
Cold abscess of the anterior abdominal wall: an unusual primary presentation. 38
24027388 2012
46
Education and imaging. Gastrointestinal: Tuberculosis of the sigmoid colon--a cautionary tale. 38
22011300 2011
47
Tuberculous appendicitis. 38
21727739 2011
48
Gastrointestinal tuberculosis with anal and perianal involvement misdiagnosed as Crohn's disease for 15 years. 38
21479355 2011
49
Cecal obstruction due to primary intestinal tuberculosis: a case series. 38
21450062 2011
50
[Ulcerated lesion of the cecum as a form of presentation of gastrointestinal tuberculosis]. 38
22011613 2011

Variations for Gastrointestinal Tuberculosis

Expression for Gastrointestinal Tuberculosis

Search GEO for disease gene expression data for Gastrointestinal Tuberculosis.

Pathways for Gastrointestinal Tuberculosis

Pathways related to Gastrointestinal Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.13 IFNG CRP ALB
2 10.87 TBP IFNG

GO Terms for Gastrointestinal Tuberculosis

Sources for Gastrointestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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