MCID: GST051
MIFTS: 34

Gastrointestinal Tuberculosis

Categories: Infectious diseases, Gastrointestinal diseases, Endocrine diseases

Aliases & Classifications for Gastrointestinal Tuberculosis

MalaCards integrated aliases for Gastrointestinal Tuberculosis:

Name: Gastrointestinal Tuberculosis 12 15
Tuberculosis, Gastrointestinal 44 73
Tuberculosis of Intestines, Peritoneum, and Mesenteric Glands 12
Tuberculosis of Intestines, Peritoneum and Mesenteric Glands 12
Tuberculosis of Gastrointestinal Tract 12

Classifications:



External Ids:

Disease Ontology 12 DOID:404
MeSH 44 D014385
ICD10 33 A18.3
UMLS 73 C0041312

Summaries for Gastrointestinal Tuberculosis

Disease Ontology : 12 An abdominal tuberculosis that results in infection located in gastrointestinal tract. The infection has symptom abdominal pain, has symptom weight loss, has symptom fever, has symptom anorexia, has symptom change in bowel habits, has symptom nausea, and has symptom vomiting.

MalaCards based summary : Gastrointestinal Tuberculosis, also known as tuberculosis, gastrointestinal, is related to intestinal tuberculosis and hepatic tuberculosis, and has symptoms including abdominal pain, weight loss and fever. An important gene associated with Gastrointestinal Tuberculosis is TBP (TATA-Box Binding Protein), and among its related pathways/superpathways is Glucocorticoid receptor regulatory network. The drug Antitubercular Agents has been mentioned in the context of this disorder. Affiliated tissues include gastrointestinal tract, colon and lymph node, and related phenotypes are homeostasis/metabolism and muscle

Related Diseases for Gastrointestinal Tuberculosis

Diseases related to Gastrointestinal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 intestinal tuberculosis 31.5 ABCB8 CD53
2 hepatic tuberculosis 31.2 ALB SMUG1
3 pulmonary tuberculosis 29.4 ADA IFNG
4 tuberculous peritonitis 29.0 ADA ALB IFNG SMUG1 TBP
5 abdominal tuberculosis 28.6 ABCB8 ADA ALB TBP
6 oral tuberculosis 10.9
7 esophageal tuberculosis 10.9
8 constrictive pericarditis 10.4 ADA ALB
9 pleural disease 10.4 ADA ALB
10 cryptococcal meningitis 10.3 ADA IFNG
11 viral meningitis 10.3 ADA IFNG
12 chronic graft versus host disease 10.3 ALB IFNG
13 pleurisy 10.3 ADA IFNG
14 chronic inflammatory demyelinating polyradiculoneuropathy 10.3 ALB IFNG
15 fascioliasis 10.3 ALB IFNG
16 hypersplenism 10.3 ALB IFNG
17 hemorrhagic fever 10.3 ALB IFNG
18 peritonitis 10.2 ADA ALB
19 hepatitis e 10.2 ALB IFNG
20 polyradiculoneuropathy 10.2 ALB IFNG
21 typhoid fever 10.2 ALB IFNG
22 dengue hemorrhagic fever 10.2 ALB IFNG
23 salmonellosis 10.2 ALB IFNG
24 filariasis 10.2 ALB IFNG
25 food allergy 10.2 ALB IFNG
26 gastroenteritis 10.2 ALB IFNG
27 intestinal disease 10.1 ALB IFNG
28 hypersensitivity reaction disease 10.1 ALB IFNG
29 schistosomiasis 10.1 ALB IFNG
30 respiratory system disease 10.1 ALB IFNG
31 acquired immunodeficiency syndrome 10.1 ALB IFNG
32 trypanosomiasis 10.1 ALB IFNG
33 immune system disease 10.0 ALB IFNG
34 omenn syndrome 10.0 ADA IFNG
35 sarcoidosis 1 10.0 ADA IFNG
36 klatskin's tumor 9.9 ALB SMUG1
37 pleural tuberculosis 9.9 ADA IFNG TBP
38 non-secretory myeloma 9.9 ALB SMUG1
39 extrapulmonary tuberculosis 9.9 ADA IFNG TBP
40 gastrointestinal system disease 9.9 ALB IFNG
41 immune deficiency disease 9.8 ADA IFNG
42 primary bacterial infectious disease 9.8 ADA ALB IFNG
43 meningitis 9.8 ADA ALB IFNG
44 eumycotic mycetoma 9.8 IFNG SMUG1
45 visceral leishmaniasis 9.8 ADA ALB IFNG
46 hypersensitivity reaction type iv disease 9.8 IFNG SMUG1
47 temporal arteritis 9.8 IFNG SMUG1
48 crohn's disease 9.7
49 gastrointestinal system cancer 9.7 ALB SMUG1
50 amyloidosis 9.6

Graphical network of the top 20 diseases related to Gastrointestinal Tuberculosis:



Diseases related to Gastrointestinal Tuberculosis

Symptoms & Phenotypes for Gastrointestinal Tuberculosis

Symptoms:

12
  • abdominal pain
  • weight loss
  • fever
  • anorexia
  • change in bowel habits
  • nausea
  • vomiting

MGI Mouse Phenotypes related to Gastrointestinal Tuberculosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.43 ABCB8 ADA ALB IFNG SMUG1 TBP
2 muscle MP:0005369 8.92 ABCB8 ADA ALB IFNG

Drugs & Therapeutics for Gastrointestinal Tuberculosis

Drugs for Gastrointestinal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Antitubercular Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Treatment Duration for Abdominal Tuberculosis Completed NCT01124929 Phase 3 RNTCP Category I treatment for 6 months;RNTCP Category I treatment for 9months

Search NIH Clinical Center for Gastrointestinal Tuberculosis

Cochrane evidence based reviews: tuberculosis, gastrointestinal

Genetic Tests for Gastrointestinal Tuberculosis

Anatomical Context for Gastrointestinal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Gastrointestinal Tuberculosis:

19
Gastrointestinal Tract

MalaCards organs/tissues related to Gastrointestinal Tuberculosis:

41
Colon, Lymph Node

Publications for Gastrointestinal Tuberculosis

Articles related to Gastrointestinal Tuberculosis:

(show top 50) (show all 54)
# Title Authors Year
1
Gastrointestinal Tuberculosis Presenting as Malnutrition and Distal Colonic Bowel Obstruction. ( 29682364 )
2018
2
Gastrointestinal tuberculosis following renal transplantation accompanied with septic shock and acute respiratory distress syndrome: a survival case presentation. ( 29179699 )
2017
3
Gastrointestinal Tuberculosis. ( 28084201 )
2016
4
Clinico-Pathological Profile and Surgical Outcome of Patients of Gastrointestinal Tuberculosis Undergoing Laparotomy. ( 28044950 )
2016
5
Management of Severe Gastrointestinal Tuberculosis with Injectable Antituberculous Drugs. ( 26543395 )
2015
6
Gastrointestinal tuberculosis is not associated with proton pump inhibitors: a retrospective cohort study. ( 23345949 )
2013
7
A case series of gastrointestinal tuberculosis in renal transplant patients. ( 24558621 )
2013
8
Multiplex PCR for rapid diagnosis of gastrointestinal tuberculosis. ( 23853431 )
2013
9
Gastrointestinal tuberculosis with anal and perianal involvement misdiagnosed as Crohn's disease for 15 years. ( 21479355 )
2011
10
Education and imaging. Gastrointestinal: Tuberculosis of the sigmoid colon--a cautionary tale. ( 22011300 )
2011
11
Gastrointestinal tuberculosis in renal transplant recipients: case report and review of the literature. ( 20626712 )
2011
12
Gastrointestinal tuberculosis: a diagnosis not to miss. ( 21127760 )
2010
13
Diagnosis of gastrointestinal tuberculosis: Using cytomorphological, microbiological, immunological and molecular techniques - A study from Central India. ( 23105903 )
2010
14
Diagnosing lower gastrointestinal tuberculosis: colonoscopy is essential. ( 20012439 )
2010
15
Morphological spectrum of gastrointestinal tuberculosis. ( 19624086 )
2009
16
Diagnostic challenge of gastrointestinal tuberculosis: a report of 34 cases and an overview of the literature. ( 19842436 )
2009
17
Gastrointestinal tuberculosis as a cause of massive bleeding. ( 19789515 )
2009
18
Gastrointestinal tuberculosis. ( 19551320 )
2009
19
Intra-abdominal and gastrointestinal tuberculosis. ( 17868413 )
2007
20
Gastrointestinal tuberculosis: an unusual presentation. ( 17350893 )
2007
21
Massive intestinal bleeding in a child with superior mesenteric artery aneurysm and gastrointestinal tuberculosis. ( 16877995 )
2006
22
CT and MR imaging of gastrointestinal tuberculosis. ( 16999319 )
2006
23
Gastrointestinal tuberculosis: 17 cases collected in 4 hospitals in the northeastern suburb of Paris. ( 15864206 )
2005
24
Protean manifestations of gastrointestinal tuberculosis. ( 14750373 )
2003
25
Gastrointestinal tuberculosis. ( 12864956 )
2003
26
Massive gastrointestinal tuberculosis in a young patient without immunosuppression. ( 14562420 )
2003
27
Perforations and fistulae in gastrointestinal tuberculosis. ( 12423461 )
2002
28
Diagnosing gastrointestinal tuberculosis. ( 11129281 )
2000
29
Gastrointestinal tuberculosis: an eighteen-patient experience and review. ( 10875468 )
2000
30
Juvenile fulminant adnexal tuberculosis caused by gastrointestinal tuberculosis immediately after ovarian cystectomy. ( 11810543 )
2000
31
Generalized AA-amyloidosis in a 58-year-old Caucasian woman with an 18-month history of gastrointestinal tuberculosis. ( 10071242 )
1999
32
Diagnostic imaging of abdominal tuberculosis: gastrointestinal tract, peritoneum, lymph nodes. ( 9673140 )
1998
33
Case report: gastrointestinal tuberculosis simulating Crohn's disease. ( 8792305 )
1996
34
Pulmonary acremonium abscesses and gastrointestinal tuberculosis manifested as massive upper gastrointestinal bleeding. ( 8538941 )
1995
35
Gastrointestinal tuberculosis in renal transplantation: a case report and review. ( 7579745 )
1995
36
Protean manifestation of gastrointestinal tuberculosis: report on 130 patients. ( 7797832 )
1995
37
Diagnosis of gastrointestinal tuberculosis. ( 7618199 )
1994
38
Gastrointestinal tuberculosis in patients with pulmonary tuberculosis. ( 2385737 )
1990
39
Perforated gastrointestinal tuberculosis. ( 2384036 )
1990
40
Gastrointestinal tuberculosis. Report of four cases. ( 2209280 )
1990
41
Gastrointestinal tuberculosis: resurgence of an old pathogen. ( 2643908 )
1989
42
The prolonged course of gastrointestinal tuberculosis. ( 2584669 )
1989
43
Gastrointestinal tuberculosis. ( 3563463 )
1986
44
Gastrointestinal tuberculosis. The great mimic still at large. ( 4006638 )
1985
45
Gastrointestinal tuberculosis: a retrospective review of 109 cases in a district general hospital. ( 4059505 )
1985
46
Medical management of gastrointestinal tuberculosis. ( 7108876 )
1982
47
Pitfalls in the diagnosis of gastrointestinal tuberculosis. ( 7234829 )
1981
48
Gastrointestinal tuberculosis. ( 386522 )
1979
49
Radiographic manifestations of gastrointestinal tuberculosis. ( 547370 )
1979
50
Gastrointestinal tuberculosis mimicking cancer--a reminder. ( 696717 )
1978

Variations for Gastrointestinal Tuberculosis

Expression for Gastrointestinal Tuberculosis

Search GEO for disease gene expression data for Gastrointestinal Tuberculosis.

Pathways for Gastrointestinal Tuberculosis

Pathways related to Gastrointestinal Tuberculosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.54 IFNG TBP

GO Terms for Gastrointestinal Tuberculosis

Sources for Gastrointestinal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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