Gemistocytic Astrocytoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Gemistocytic Astrocytoma

MalaCards integrated aliases for Gemistocytic Astrocytoma:

Name: Gemistocytic Astrocytoma ¹² ⁵⁹ ⁵⁵ ¹⁵ ⁷³

Gemistocytic Astrocytic Tumor ¹²

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Neuronal diseases

See all MalaCards categories (disease lists)

ICD10: ³⁴

Neoplasms

Malignant neoplasms of eye, brain and other parts of central nervous system

Malignant neoplasm of brain

Malignant neoplasm: Brain, unspecified

Orphanet: ⁵⁹

Rare neurological diseases

External Ids:

Disease Ontology ¹² DOID:7005

MeSH ⁴⁴ D001254

NCIt ⁵⁰ C4321

SNOMED-CT ⁶⁸ 73982001

Orphanet ⁵⁹ ORPHA251604

UMLS via Orphanet ⁷⁴ C0334581

ICD10 via Orphanet ³⁴ C71.9

UMLS ⁷³ C0334581

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Summaries for Gemistocytic Astrocytoma

MalaCards based summary : Gemistocytic Astrocytoma, also known as gemistocytic astrocytic tumor, is related to fibrillary astrocytoma and giant cell glioblastoma, and has symptoms including seizures, headache and motor manifestations. An important gene associated with Gemistocytic Astrocytoma is LINC01089 (Long Intergenic Non-Protein Coding RNA 1089), and among its related pathways/superpathways are Signaling by ERBB4 and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Histamine and Cyproheptadine have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and thyroid, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

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Related Diseases for Gemistocytic Astrocytoma

Diseases related to Gemistocytic Astrocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 58)

#	Related Disease	Score	Top Affiliating Genes
1	fibrillary astrocytoma	32.2	GFAP IDH2
2	giant cell glioblastoma	30.1	GFAP PTEN
3	subependymal giant cell astrocytoma	30.0	GFAP S100B
4	oligodendroglioma	29.5	GFAP IDH2 PTEN S100B
5	astrocytoma	10.7
6	thyroid cancer, nonmedullary, 1	10.1
7	fibrosarcoma	10.1
8	vasculitis	10.1
9	glioblastoma	10.1
10	adult astrocytic tumour	10.0	IDH2 PTEN
11	nervous system cancer	10.0	GFAP PTEN
12	oligoastrocytoma	10.0	GFAP IDH2
13	protoplasmic astrocytoma	10.0	GFAP IDH2
14	anaplastic oligodendroglioma	10.0	GFAP IDH2
15	glioma susceptibility 1	10.0	GFAP IDH2
16	gliomatosis cerebri	10.0	GFAP PTEN
17	hydromyelia	10.0	PTEN S100B
18	mixed type thymoma	9.9	PTEN S100B
19	ependymoma	9.9	GFAP S100B
20	intracranial cysts	9.9	GFAP S100B
21	syringocystadenoma papilliferum	9.9	GFAP S100B
22	chordoid meningioma	9.9	GFAP S100B
23	dysembryoplastic neuroepithelial tumor	9.9	GFAP S100B
24	meningioma, familial	9.9	GFAP PTEN
25	spindle cell rhabdomyosarcoma	9.9	GFAP S100B
26	myxopapillary ependymoma	9.9	GFAP S100B
27	papillary ependymoma	9.9	GFAP S100B
28	chordoid glioma	9.9	GFAP S100B
29	syringoma	9.9	GFAP S100B
30	angiocentric glioma	9.9	GFAP S100B
31	pineocytoma	9.9	GFAP S100B
32	papilloma of choroid plexus	9.9	GFAP S100B
33	granular cell tumor	9.9	GFAP S100B
34	traumatic brain injury	9.9	GFAP S100B
35	brain injury	9.9	GFAP S100B
36	optic nerve glioma	9.9	GFAP S100B
37	meningioma, radiation-induced	9.9	GFAP S100B
38	myoepithelioma	9.9	GFAP S100B
39	megalencephaly	9.9	PTEN S100B
40	ganglioglioma	9.9	GFAP S100B
41	neurilemmoma	9.9	GFAP S100B
42	neuroma	9.8	GFAP S100B
43	supratentorial cancer	9.8	GFAP IDH2 PTEN
44	cerebrum cancer	9.8	GFAP IDH2 PTEN
45	grade iii astrocytoma	9.8	GFAP IDH2 PTEN
46	central nervous system cancer	9.8	GFAP IDH2 PTEN
47	hemangioblastoma	9.8	GFAP S100B
48	neuronal ceroid-lipofuscinoses	9.8	GFAP S100B
49	pleomorphic adenoma	9.8	GFAP S100B
50	brain cancer	9.8	GFAP IDH2 PTEN

Graphical network of the top 20 diseases related to Gemistocytic Astrocytoma:

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Symptoms & Phenotypes for Gemistocytic Astrocytoma

UMLS symptoms related to Gemistocytic Astrocytoma:

seizures, headache, motor manifestations, sensory manifestations

GenomeRNAi Phenotypes related to Gemistocytic Astrocytoma according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased shRNA abundance (Z-score < -2)	GR00366-A-104	9.17	S100B
2	Decreased shRNA abundance (Z-score < -2)	GR00366-A-145	9.17	S100B
3	Decreased shRNA abundance (Z-score < -2)	GR00366-A-213	9.17	S100B
4	Decreased shRNA abundance (Z-score < -2)	GR00366-A-48	9.17	S100B
5	Decreased shRNA abundance (Z-score < -2)	GR00366-A-66	9.17	PTEN S100B
6	Decreased shRNA abundance (Z-score < -2)	GR00366-A-87	9.17	PTEN

Sources

Drugs & Therapeutics for Gemistocytic Astrocytoma

Drugs for Gemistocytic Astrocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Histamine

Approved, Investigational

Phase 3

51-45-6, 75614-87-8

774

Synonyms:

.beta.-Imidazolyl-4-ethylamine

[3H]histamine

1avn

1H-Imidazole-4-ethanamine

1H-Imidazole-5-ethanamine

1qft

2-(1H-imidazol-4-yl)ethan-1-amine

2-(1H-Imidazol-4-yl)ethanamine

2-(1H-Imidazol-4-yl)ethylamine

2-(1H-imidazol-5-yl)ethanamine

2-(1H-Imidazol-5-yl)ethanamine

2-(1H-Imidazol-5-yl)ethylamine

2-(3H-Imidazol-4-yl)-ethylamine

2-(4-Imidazolyl)ethanamine

2-(4-imidazolyl)ethylamine

2-(4-Imidazolyl)ethylamine

2-[4-Imidazolyl]ethylamine

2-Imidazol-4-ylethylamine

2-Imidazol-4-yl-ethylamine

4-(2-Aminoethyl)-1H-imidazole

4-(2-Aminoethyl)imidazole

4-imidazoleethylamine

4-Imidazoleethylamine

51-45-6

53290_FLUKA

5-imidazoleethylamine

5-Imidazoleethylamine

64422-25-9

924364-91-0

AC-13185

AC1L19ZT

AC1Q54BV

AC1Q54BW

AKOS000274386

ALBB-005968

BCBcMAP01_000250

beta-aminoethylglyoxaline

beta-Aminoethylglyoxaline

beta-aminoethylimidazole

beta-Aminoethylimidazole

beta-aminothethylglyoxaline

beta-Aminothethylglyoxaline

beta-Imidazolyl-4-ethylamine

b-Imidazolyl-4-ethylamine

Bio1_000487

Bio1_000976

Bio1_001465

Bio2_000389

Bio2_000869

bmse000744

BSPBio_001117

BSPBio_002124

C00388

CCRIS 6535

Ceplene

CHEBI:18295

CHEMBL90

CID774

D08040

Dihydrochloride, histamine

DivK1c_000308

EINECS 200-100-6

Eramin

Ergamine

Ergotidine

F411C768-A159-4FC0-A195-291A08BB03AA

Free histamine

H7125_SIGMA

histamine

Histamine (DCF)

Histamine [USAN]

Histamine Base

Histamine dihydrochloride

Histamine hydrochloride

Histamine, Free Base

Histaminum

Histaminum (TN)

HMS1362G19

HMS1792G19

HMS1990G19

HSDB 3338

HSM

Hydrochloride, histamine

IDI1_000308

IDI1_002144

Imidazole-4-ethylamine

Istamina

Istamina [Italian]

KBio1_000308

KBio2_000457

KBio2_001325

KBio2_003025

KBio2_003893

KBio2_005593

KBio2_006461

KBio3_000853

KBio3_000854

KBio3_001344

KBioGR_000457

KBioGR_001580

KBioSS_000457

KBioSS_001325

L000292

L-Histamin base

L-histamine

L-Histamine

Lopac0_000595

Lopac-H-7250

LS-75835

MLS000069447

MolPort-001-785-597

MolPort-002-042-264

NCGC00015513-01

NCGC00015513-08

NCGC00093371-02

NCGC00093371-03

NCGC00093371-04

NCGC00093371-05

nchembio.87-comp54

nchembio714-comp1

NINDS_000308

NSC 33792

NSC33792

Peremin

SDCCGMLS-0066601.P001

SMP1_000151

SMR000059091

SPBio_000729

Spectrum_000845

Spectrum2_000665

Spectrum3_000452

Spectrum4_000960

Spectrum5_000796

ST073926

STK346752

STOCK5S-55669

Theramine

UNII-820484N8I3

WLN: T5M CNJ D2Z

ZERO/004089

2

Cyproheptadine

Approved

Phase 3

129-03-3

2913

Synonyms:

129-03-3

1-methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine

1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine

1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine

1-Methyl-4-(5H-dibenzo(a,D)cycloheptenylidene)piperidine

4-(5-dibenzo(a,D)Cyclohepten-5-ylidine)-1-methylpiperidine

4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine

4-(5-Dibenzo(a,D)cyclohepten-5-ylidine)-1-methylpiperidine

4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidene

4-(5H-dibenzo(a,D)Cyclohepten-5-ylidene)-1-methylpiperidine

4-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine

4-(5H-Dibenzo(a,D)cyclohepten-5-ylidene)-1-methylpiperidine

4-(5H-dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine

4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine

41354-29-4

4-dibenzo[a,D]Cyclohepten-5-ylidene-1-methyl-piperidine

4-Dibenzo[a,D]cyclohepten-5-ylidene-1-methyl-piperidine

5-(1-methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene

5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene

5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,D)cyclopheptene

5-20-08-00500 (Beilstein Handbook Reference)

AC1L1ER8

AKOS004119847

Antergan

Axoprol

BIDD:GT0324

Biomol-NT_000131

BPBio1_000096

BPBio1_000155

BRD-K28143534-001-01-4

BRD-K28143534-003-03-6

BRN 1685976

BSPBio_000086

C06935

CAS-969-33-5

CCRIS 5232

CHEBI:4046

CHEMBL516

CID2913

Ciproheptadina

Ciproheptadina [INN-Spanish]

Ciprovit

Ciprovit (TN)

Cypoheptadine

Cyproheptadiene

Cyproheptadin

Cyproheptadine

CYPROHEPTADINE

Cyproheptadine (INN)

Cyproheptadine [INN:BAN]

Cyproheptadine Hcl

Cyproheptadinum

Cyproheptadinum [INN-Latin]

D07765

DB00434

Dibenzosuberonone/Cyproheptadine

Dihexazin

Dronactin

EINECS 204-928-9

Eiproheptadine

Glutodina

HMS2090P20

HSDB 3048

L001016

Lopac0_000246

Lopac-C-6022

LS-114933

MK 141

MolPort-002-507-777

NCGC00015252-01

NCGC00015252-02

NCGC00015252-03

NCGC00015252-09

NCGC00024293-02

NCGC00024293-04

NCGC00024293-05

nchembio.559-comp10

Oprea1_498140

PDSP1_001229

PDSP2_001213

Periactin

Periactine

Periactinol

Peritol

Prestwick0_000103

Prestwick1_000103

Prestwick2_000103

Prestwick3_000103

SPBio_002025

STK802098

Tocris-0996

UNII-2YHB6175DO

Viternum

3

Dermatologic Agents

Phase 3,Phase 1

4

Serotonin Agents

Phase 3

5

Anti-Allergic Agents

Phase 3

6

Serotonin Antagonists

Phase 3

7

Histamine H1 Antagonists

Phase 3

8

Histamine Phosphate

Phase 3

51-74-1

65513

Synonyms:

1H-Imidazole-4-ethanamine, phosphate (1:2)

2-Imidazol-4-ylethylamine orthophosphoric acid (1:2)

4-(2-Aminoethyl)imidazole bis(dihydrogen phosphate)

4-(2-Aminoethyl)imidazole di-acid phosphate

4-2(2-Aminoethyl)Imidazole-Di-Acid Phosphate

51-74-1

53623-99-7

74-56-6

AC1L23E4

CID65513

D04445

DB00667

EINECS 200-118-4

H0147

Histamine acid phosphate

Histamine biphosphate

Histamine dihydrogen phosphate

Histamine diphosphate

Histamine phosphate (1:2)

Histamine phosphate (TN)

Histamine phosphate (USP)

Histamine phosphate [USP]

Histamine positive

LS-78569

UNII-QWB37T4WZZ

9

Antipruritics

Phase 3

10

Neurotransmitter Agents

Phase 3,Not Applicable

11

Histamine Antagonists

Phase 3

12

Gastrointestinal Agents

Phase 3,Not Applicable

13

Serotonin

Investigational, Nutraceutical

Phase 3

50-67-9

5202

Synonyms:

3-(2-Aminoethyl)-1H-indol-5-ol

3-(2-Aminoethyl)indol-5-ol

3-(b-Aminoethyl)-5-hydroxyindole

5 Hydroxytryptamine

5-HT

5-HTA

5-Hydroxy-3-(b-aminoethyl)indole

5-Hydroxyltryptamine

5-Hydroxytriptamine

5-Hydroxytryptamine

5-Hydroxy-tryptamine

Antemovis

DS Substance

Enteramin

Enteramine

Hippophaine

Hydroxytryptamine

Serotonine

sérotonine

thrombocytin

Thrombocytin

thrombotonin

Thrombotonin

14

Verteporfin

Approved, Investigational

Phase 1

129497-78-5

15

Trioxsalen

Approved

Phase 1

3902-71-4

5585

Synonyms:

2',4,8-Trimethylpsoralen

2,5,9-Trimethyl-7H-furo(3,2-g)benzopyran-7-one

4,5',8-Trimethylpsoralen

4,8,5'-Trimethylpsoralen

6-Hydroxy-b,2,7-trimethyl-5-benzofuranacrylate, delta-lactone

6-Hydroxy-b,2,7-trimethyl-5-benzofuranacrylate, δ-lactone

6-Hydroxy-b,2,7-trimethyl-5-benzofuranacrylic acid, delta-lactone

6-Hydroxy-b,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone

6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylate, delta-lactone

6-Hydroxy-beta,2,7-trimethyl-5-benzofuranacrylic acid, delta-lactone

6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylate, δ-lactone

6-Hydroxy-β,2,7-trimethyl-5-benzofuranacrylic acid, δ-lactone

ICN brand OF trioxsalen

trimethylpsoralen

Trimethylpsoralen

Trioxisaleno

Trioxisalenum

Trioxsalen

trioxysalen

Trioxysalen

Trioxysalene

Trioxysalenum

trisoralen

Trisoralen

16

Photosensitizing Agents

Phase 1

17

Dihematoporphyrin Ether

Phase 1

18

Dopamine

Approved

Not Applicable

51-61-6, 62-31-7

681

Synonyms:

(3H)-Dopamine

.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane

.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)

1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium

153C5321-5FEE-4B0B-8925-F388F0EEEBD1

2-(3,4-dihydroxyphenyl)ethylamine

2-(3,4-Dihydroxyphenyl)ethylamine

2-benzenediol

3,4 Dihydroxyphenethylamine

3,4-dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine hydrochloride

3,4-Dihydroxyphenylethylamine

3-Hydroxtyramine

3-Hydroxytyramine

3-Hydroxytyramine Hydrobromide

3-Hydroxytyramine hydrochloride

4-(2-Aminoethyl)-1,

4-(2-aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-bezenediol

4-(2-Aminoethyl)benzene-1,2-diol

4-(2-aminoethyl)catechol

4-(2-Aminoethyl)catechol

4-(2-aminoethyl)pyrocatechol

4-(2-aminoethyl)-pyrocatechol

4-(2-Aminoethyl)pyrocatechol

4-(2-Aminoethyl)-pyrocatechol

4-(2-Aminoethyl)pyrocatechol hydrochloride

50444-17-2

51-61-6

62-31-7 (HYDROCHLORIDE)

a-(3,4-Dihydroxyphenyl)-b-aminoethane

AC1L19S5

AC1Q54AX

AC1Q54AY

AKOS003790978

alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane

ASL 279

BIDD:ER0506

Biomol-NT_000001

BPBio1_001123

BSPBio_001932

C03758

CHEBI:18243

CHEMBL59

CID681

cMAP_000036

cMAP_000065

D07870

DB00988

Deoxyepinephrine

DivK1c_000780

Dopamin

Dopamina

Dopamina [INN-Spanish]

dopamine

Dopamine

Dopamine (INN)

Dopamine (USAN)(*hydrochloride*)

Dopamine [INN:BAN]

Dopamine hydrochloride

Dopaminum

Dopaminum [INN-Latin]

Dopastat

Dophamine

Dynatra

EINECS 200-110-0

HSDB 3068

Hydrochloride, dopamine

Hydroxytyramin

hydroxytyramine

Hydroxytyramine

IDI1_000780

intropin

Intropin

Intropin [*hydrochloride*]

IP 498

KBio1_000780

KBio2_001492

KBio2_002388

KBio2_002484

KBio2_004060

KBio2_004956

KBio2_005052

KBio2_006628

KBio2_007524

KBio2_007620

KBio3_001152

KBio3_002867

KBio3_002962

KBioGR_001129

KBioGR_002388

KBioGR_002484

KBioSS_001492

KBioSS_002393

KBioSS_002491

KW-3-060

L000232

L-DOPAMINE

LDP

Lopac0_000586

Lopac-H-8502

LS-159

Medopa (TN)

m-Hydroxytyramine hydrochloride

MolPort-001-641-000

NCGC00015519-01

NCGC00015519-08

NCGC00096050-01

NCGC00096050-02

NCGC00096050-03

NCGC00096050-04

NCGC00096050-05

nchembio.105-comp9

nchembio.107-comp4

nchembio.284-comp1

nchembio.78-comp16

nchembio.89-comp3

nchembio705-8

nchembio801-comp8

NINDS_000780

NSC 173182

NSC169105

NSC173182

Oprea1_088821

Oxytyramine

Pyrocatechol, 4-(2-aminoethyl)- (8CI)

Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride

Revimine

Revivan

SPBio_001205

Spectrum_001012

SPECTRUM1505155

Spectrum2_001023

Spectrum3_000406

Spectrum4_000525

Spectrum5_000945

ST048774

STK301601

UNII-VTD58H1Z2X

UPCMLD0ENAT5885989:001

19

Dopamine Agents

Not Applicable

20

Dihydroxyphenylalanine

Not Applicable

21

Fluorides

Not Applicable

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer	Terminated	NCT01132547	Phase 3	cyproheptadine hydrochloride
2	Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors	Unknown status	NCT00002647	Phase 1	verteporfin
3	Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma	Completed	NCT01273090	Phase 1	imetelstat sodium
4	18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas	Terminated	NCT02175745	Not Applicable	18F-fluoro-dihydroxyphenylalanine
5	Efficacy of 68Ga-DOTATOC Positron Emission Tomography (PET) CT in Children and Young Adults With Brain Tumors	Withdrawn	NCT02194452	Not Applicable

Search NIH Clinical Center for Gemistocytic Astrocytoma

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Genetic Tests for Gemistocytic Astrocytoma

Sources

Anatomical Context for Gemistocytic Astrocytoma

MalaCards organs/tissues related to Gemistocytic Astrocytoma:

⁴¹

Brain, Spinal Cord, Thyroid

Sources

Publications for Gemistocytic Astrocytoma

Articles related to Gemistocytic Astrocytoma:

(show all 14)

#	Title	Authors	Year
1	Synchronous gemistocytic astrocytoma IDH-mutant and oligodendroglioma IDH-mutant and 1p/19q-codeleted in a patient with CCDC26 polymorphism. ( 28550371 )	Vaubel R.A....Kipp B.R.	2017
2	Magnetic resonance imaging features of gemistocytic astrocytoma. ( 27766769 )	Simkin P.M....Gaillard F.	2016
3	Perfusion MR imaging and MR spectroscopy of gemistocytic astrocytoma. ( 22115534 )	Godefroy A....Gerardin E.	2012
4	Unusual synchronous presentation of maxillary sinus fibrosarcoma and gemistocytic astrocytoma with a complication called leukocytoclastic vasculitis: a case report. ( 19756200 )		2009
5	Immunohistochemical features of a feline spinal cord gemistocytic astrocytoma. ( 18987242 )	Aloisio F....Edwards J.F.	2008
6	Cytologic characteristics of subependymal giant cell astrocytoma in squash smears: morphometric comparisons with gemistocytic astrocytoma and giant cell glioblastoma. ( 17536538 )		2007
7	Congenital gemistocytic astrocytoma in a fetus. ( 15864706 )	Nozaki M....Sawamura Y.	2006
8	November 2003: neonatal female with congenital brain tumor. Congenital gemistocytic astrocytoma. ( 15193038 )	Bleggi-Torres L.F....AraA_jo J.C.	2004
9	Cystic gemistocytic astrocytoma in an adolescent. ( 29542484 )	Prasad V....Dinakar I.	1995
10	A gemistocytic astrocytoma demonstrated high intensity on MR images. Protein hydration layer. ( 2398944 )	Abe K....Bitoh S.	1990
11	Multiple primary malignant tumours: gemistocytic astrocytoma with leptomeningeal spreading and papillary thyroid carcinoma. A case report. ( 2251958 )	Agostini L....Cavaliere A.	1990
12	Gemistocytic astrocytoma in a one-month-old llama. ( 2365629 )		1990
13	Development of Hodgkin's disease in a patient receiving procarbazine, CCNU, and vincristine therapy for a gemistocytic astrocytoma. ( 626997 )		1978
14	Gemistocytic astrocytoma: cytological observations on the rate of hydrolysis of some phosphoric acid esters. ( 13301910 )		1955

Sources

Genes for Gemistocytic Astrocytoma

Genes related to Gemistocytic Astrocytoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	LINC01089	Long Intergenic Non-Protein Coding RNA 1089	RNA Gene	150	Experimental evidence: Expression ³⁹	26252651
2	IDH2	Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial	Protein Coding	38.81	DISEASES inferred ¹⁵
3	GFAP	Glial Fibrillary Acidic Protein	Protein Coding	23.6	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	15677537 8773153
4	S100B	S100 Calcium Binding Protein B	Protein Coding	20.58	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵	1882640
5	PTEN	Phosphatase And Tensin Homolog	Protein Coding	16.64	Novoseek inferred ⁵⁵	9650746

Sources

Variations for Gemistocytic Astrocytoma

Sources

Expression for Gemistocytic Astrocytoma

Search GEO for disease gene expression data for Gemistocytic Astrocytoma.

Sources

Pathways for Gemistocytic Astrocytoma

Pathways related to Gemistocytic Astrocytoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Signaling by ERBB4 ⁶⁶ Show member pathways Downregulation of ERBB4 signaling ⁶⁶ ErbB4 signaling events ¹ Nuclear signaling by ERBB4 ⁶⁶	10.99	GFAP S100B
2	Neural Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	10.52	GFAP S100B

Sources

GO Terms for Gemistocytic Astrocytoma

Biological processes related to Gemistocytic Astrocytoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cellular response to hypoxia	GO:0071456	9.32	PTEN S100B
2	central nervous system development	GO:0007417	9.26	PTEN S100B
3	memory	GO:0007613	9.16	PTEN S100B
4	learning or memory	GO:0007611	8.96	PTEN S100B
5	long-term synaptic potentiation	GO:0060291	8.8	GFAP PTEN S100B

Sources

Sources for Gemistocytic Astrocytoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia