MCID: GNR023
MIFTS: 24

Generalized Eruptive Histiocytosis

Categories: Bone diseases, Rare diseases, Skin diseases

Aliases & Classifications for Generalized Eruptive Histiocytosis

MalaCards integrated aliases for Generalized Eruptive Histiocytosis:

Name: Generalized Eruptive Histiocytosis 58
Generalized Eruptive Histiocytoma 58 70
Histiocytosis, Generalized Eruptive 70

Characteristics:

Orphanet epidemiological data:

58
generalized eruptive histiocytosis
Inheritance: Not applicable;

Classifications:

Orphanet: 58  
Rare systemic and rhumatological diseases
Rare skin diseases


External Ids:

ICD10 via Orphanet 33 D76.3
Orphanet 58 ORPHA157991
UMLS 70 C0347404 C0544799

Summaries for Generalized Eruptive Histiocytosis

MalaCards based summary : Generalized Eruptive Histiocytosis, also known as generalized eruptive histiocytoma, is related to langerhans cell histiocytosis and juvenile xanthogranuloma. An important gene associated with Generalized Eruptive Histiocytosis is F13A1 (Coagulation Factor XIII A Chain). Affiliated tissues include skin, and related phenotypes are erythematous papule and erythematous macule

Wikipedia : 73 Generalized eruptive histiocytoma (also known as "Eruptive histiocytoma," and "Generalized eruptive... more...

Related Diseases for Generalized Eruptive Histiocytosis

Graphical network of the top 20 diseases related to Generalized Eruptive Histiocytosis:



Diseases related to Generalized Eruptive Histiocytosis

Symptoms & Phenotypes for Generalized Eruptive Histiocytosis

Human phenotypes related to Generalized Eruptive Histiocytosis:

58 31 (show all 13)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 erythematous papule 58 31 hallmark (90%) Very frequent (99-80%) HP:0030350
2 erythematous macule 58 31 hallmark (90%) Very frequent (99-80%) HP:0025475
3 histiocytosis 58 31 hallmark (90%) Very frequent (99-80%) HP:0100727
4 maculopapular exanthema 58 31 frequent (33%) Frequent (79-30%) HP:0040186
5 pruritus 58 31 occasional (7.5%) Occasional (29-5%) HP:0000989
6 hypereosinophilia 58 31 occasional (7.5%) Occasional (29-5%) HP:0032061
7 abnormal vitamin b12 level 58 31 occasional (7.5%) Occasional (29-5%) HP:0040126
8 elevated total serum tryptase 31 occasional (7.5%) HP:0031901
9 leukemia 58 31 very rare (1%) Very rare (<4-1%) HP:0001909
10 spotty hyperpigmentation 58 31 very rare (1%) Very rare (<4-1%) HP:0005585
11 lymphadenopathy 58 Excluded (0%)
12 increased serum mast cell beta-tryptase concentration 58 Occasional (29-5%)
13 abnormal langerhans cell morphology 58 Excluded (0%)

Drugs & Therapeutics for Generalized Eruptive Histiocytosis

Search Clinical Trials , NIH Clinical Center for Generalized Eruptive Histiocytosis

Genetic Tests for Generalized Eruptive Histiocytosis

Anatomical Context for Generalized Eruptive Histiocytosis

MalaCards organs/tissues related to Generalized Eruptive Histiocytosis:

40
Skin

Publications for Generalized Eruptive Histiocytosis

Articles related to Generalized Eruptive Histiocytosis:

(show top 50) (show all 70)
# Title Authors PMID Year
1
Generalized eruptive histiocytosis in an elderly female: A rare entity managed with PUVA therapy. 61
32954599 2020
2
Dermoscopy of Generalized Eruptive Histiocytosis: Case Report and Brief Review of the Literature. 61
32685275 2020
3
Generalized eruptive histiocytoma: Pediatric case report and review of the published work. 61
31254297 2019
4
Generalized eruptive histiocytoma developing into xanthoma disseminatum with central diabetes insipidus. 61
30859591 2019
5
Generalized eruptive histiocytosis diagnosed in light of dermoscopic findings. 61
29243820 2018
6
[Generalized eruptive histiocytosis-Juvenile xanthogranuloma: clinical spectrum in a pediatric patient]. 61
28318197 2017
7
Generalized eruptive histiocytosis associated with a novel fusion in LMNA-NTRK1. 61
27617936 2016
8
Generalized Eruptive Histiocytosis With Features of Multinucleate Cell Angiohistiocytoma. 61
26322558 2016
9
Generalized Eruptive Histiocytosis Associated With FIP1L1-PDGFRA-Positive Chronic Eosinophilic Leukemia. 61
25923837 2015
10
Generalized eruptive histiocytoma in adult patient. 61
26016960 2015
11
A case of generalized eruptive histiocytosis in a 23-year-old man. 61
25148275 2014
12
Atypical generalized eruptive histiocytosis clonally related to chronic myelomonocytic leukemia with loss of Y chromosome. 61
23639193 2013
13
Generalized eruptive histiocytoma: a rare disease in an elderly patient. 61
23539013 2013
14
Generalized eruptive histiocytosis in a patient with chronic myelomonocytic leukemia. 61
22677122 2012
15
Photoletter to the editor: Generalized eruptive histiocytoma. 61
22187581 2011
16
Generalized eruptive histiocytosis mimicking leprosy. 61
21727699 2011
17
Generalized eruptive histiocytoma. 61
23130189 2010
18
Generalized eruptive histiocytosis in an infant. 61
20169315 2010
19
Generalized eruptive histiocytoma treated with isotretinoin. 61
19426623 2009
20
Generalized eruptive histiocytosis presenting with warty lesions on face. 61
18454899 2008
21
Spontaneous regression of generalized eruptive histiocytosis: possible involvement of apoptosis? 61
17910718 2007
22
Successful treatment of generalized eruptive histiocytoma with PUVA. 61
17274780 2007
23
A case of generalized eruptive histiocytosis. 61
17989894 2007
24
Generalized eruptive histiocytoma: a pediatric case. 61
17229617 2006
25
[Generalized eruptive histiocytoma]. 61
16540049 2006
26
Generalized eruptive histiocytoma with rapid progression and resolution following exanthema subitum. 61
15807699 2005
27
Generalized eruptive histiocytosis: a possible therapeutic cure? 61
14746649 2004
28
Generalized eruptive histiocytosis. 61
14699379 2004
29
Atypical generalized eruptive histiocytosis associated with acute monocytic leukemia. 61
14576638 2003
30
Guess what! Generalized eruptive histiocytosis (histiocytoma). 61
11872426 2002
31
Long-lasting "christmas tree rash" in an adolescent: isotopic response of indeterminate cell histiocytosis in pityriasis rosea? 61
12361135 2002
32
Generalized eruptive histiocytoma in an infant with healing in summer: long-term follow-up. 61
11251600 2001
33
Generalized eruptive histiocytoma: a pediatric case. 61
11123777 2000
34
Histiocytic disorders with spontaneous regression in infancy. 61
11085663 2000
35
Progressive nodular histiocytosis accompanied by systemic disorders. 61
10971342 2000
36
Generalized eruptive histiocytoma of childhood associated with rheumatic fever. 61
10523734 1999
37
Generalized eruptive histiocytoma of childhood. 61
10215796 1999
38
Systemic xanthohistiocytoma: a variant of xanthoma disseminatum? 61
9580148 1998
39
Non-Langerhans cell histiocytoses. A new unifying concept. 61
8902096 1996
40
Histiocytic sarcoma that mimics benign histiocytosis. 61
8793665 1996
41
Indeterminate cell histiocytosis--a clinicopathological entity with features of both X- and non-X histiocytosis. 61
8731682 1996
42
Generalized eruptive histiocytoma evolving into xanthoma disseminatum in a 4-year-old boy. 61
7662578 1995
43
A unique non-Langerhans cell histiocytosis with some features of generalized eruptive histiocytoma. 61
8034797 1994
44
Multiple eruptive cephalic histiocytomas in a case of T-cell lymphoma. A xanthomatous stage of benign cephalic histiocytosis in an adult patient? 61
8311192 1993
45
Benign cephalic histiocytosis: a distinct entity or a part of a wide spectrum of histiocytic proliferative disorders of children? A histopathological study. 61
8214388 1993
46
Generalized eruptive histiocytoma: report of a pediatric case. 61
8478484 1993
47
Generalized eruptive histiocytoma. 61
1311192 1992
48
Generalized eruptive histiocytoma: a report of a variant case showing the presence of dermal indeterminate cells. 61
1856341 1991
49
Eruptive histiocytoma. 61
2541184 1989
50
[Eruptive histiocytoma and xanthoma disseminatum as manifestations of the same disease?]. 61
2853144 1988

Variations for Generalized Eruptive Histiocytosis

Expression for Generalized Eruptive Histiocytosis

Search GEO for disease gene expression data for Generalized Eruptive Histiocytosis.

Pathways for Generalized Eruptive Histiocytosis

GO Terms for Generalized Eruptive Histiocytosis

Sources for Generalized Eruptive Histiocytosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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