MCID: GNC005
MIFTS: 27

Geniculate Ganglionitis

Categories: Neuronal diseases

Aliases & Classifications for Geniculate Ganglionitis

MalaCards integrated aliases for Geniculate Ganglionitis:

Name: Geniculate Ganglionitis 12 15 74
Facial Nerve Diseases 45 74

Classifications:



External Ids:

Disease Ontology 12 DOID:14075
ICD9CM 36 351.1
MeSH 45 D005155
SNOMED-CT 69 72839009
ICD10 34 G51 G51.1 G51.8

Summaries for Geniculate Ganglionitis

MalaCards based summary : Geniculate Ganglionitis, also known as facial nerve diseases, is related to facial nerve disease and geniculate herpes zoster, and has symptoms including oral manifestations, facial paresis and numbness along 7th cranial nerve. An important gene associated with Geniculate Ganglionitis is TNNT1 (Troponin T1, Slow Skeletal Type). The drugs Ketamine and Ondansetron have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and liver.

Wikipedia : 77 Geniculate ganglionitis or geniculate neuralgia (GN), also called nervus intermedius neuralgia, Ramsay... more...

Related Diseases for Geniculate Ganglionitis

Diseases related to Geniculate Ganglionitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 facial nerve disease 12.4
2 geniculate herpes zoster 12.2
3 moebius syndrome 10.9
4 hemangioma 10.3
5 herpes zoster 10.3
6 meningioma, familial 10.2
7 spinal meningioma 10.2
8 facial paralysis 10.2
9 neuroma 10.2
10 secretory meningioma 10.2
11 myoclonus and ataxia 10.0
12 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
13 human venous malformation 10.0
14 bell's palsy 10.0
15 leiomyoma 10.0
16 neurilemmoma 10.0
17 angiomyoma 10.0
18 herpes simplex 10.0
19 chickenpox 10.0
20 arachnoid cysts 10.0
21 hemifacial spasm 10.0

Comorbidity relations with Geniculate Ganglionitis via Phenotypic Disease Network (PDN):


Hypertension, Essential

Graphical network of the top 20 diseases related to Geniculate Ganglionitis:



Diseases related to Geniculate Ganglionitis

Symptoms & Phenotypes for Geniculate Ganglionitis

UMLS symptoms related to Geniculate Ganglionitis:


oral manifestations, facial paresis, numbness along 7th cranial nerve

Drugs & Therapeutics for Geniculate Ganglionitis

Drugs for Geniculate Ganglionitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 115)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
2
Ondansetron Approved Phase 4 99614-02-5 4595
3
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
4
Ropivacaine Approved Phase 4 84057-95-4 175805 71273
5
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 302-25-0
6
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 50-24-8 5755
7
Methylprednisolone hemisuccinate Approved Phase 4,Phase 3,Phase 2,Not Applicable 2921-57-5
8
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 83-43-2 6741
9
Acetylcholine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 51-84-3 187
10
Oxcarbazepine Approved Phase 4 28721-07-5 34312
11
Prednisolone hemisuccinate Experimental Phase 4,Phase 3,Phase 2,Not Applicable 2920-86-7
12
Cortisone Experimental Phase 4 53-06-5 222786
13 Dermatologic Agents Phase 4,Not Applicable
14 Antipsychotic Agents Phase 4,Phase 2,Phase 3,Not Applicable
15 Analgesics, Opioid Phase 4
16 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
17 Central Nervous System Depressants Phase 4,Phase 2,Phase 3,Not Applicable
18 Serotonin Antagonists Phase 4
19 Excitatory Amino Acids Phase 4,Phase 2
20 Narcotics Phase 4
21 Anesthetics Phase 4,Phase 2,Phase 3,Not Applicable
22 Excitatory Amino Acid Antagonists Phase 4,Phase 2
23 Neurotransmitter Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
24 Anesthetics, Intravenous Phase 4
25 Anesthetics, Dissociative Phase 4
26 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Not Applicable
27 Antipruritics Phase 4
28 Antiemetics Phase 4,Phase 3,Phase 2,Not Applicable
29 Tranquilizing Agents Phase 4,Phase 2,Phase 3,Not Applicable
30 Psychotropic Drugs Phase 4,Phase 2,Phase 3,Not Applicable
31 Autonomic Agents Phase 4,Phase 3,Phase 2,Not Applicable
32 Anti-Anxiety Agents Phase 4
33 Adjuvants, Anesthesia Phase 4
34 Serotonin Agents Phase 4
35 Anesthetics, General Phase 4
36 Analgesics Phase 4,Phase 2,Phase 3,Not Applicable
37 Protective Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
38 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Not Applicable
39 glucocorticoids Phase 4,Phase 3,Phase 2,Not Applicable
40 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Not Applicable
41 Methylprednisolone Acetate Phase 4,Phase 3,Phase 2,Not Applicable
42 Prednisolone acetate Phase 4,Phase 3,Phase 2,Not Applicable
43 Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
45 Hormones Phase 4,Phase 2,Phase 3,Not Applicable
46 Neuroprotective Agents Phase 4,Phase 3,Not Applicable
47 incobotulinumtoxinA Phase 4,Phase 2
48 Botulinum Toxins Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
49 Botulinum Toxins, Type A Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
50 Neuromuscular Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 113)
# Name Status NCT ID Phase Drugs
1 Postoperative Analgesia in Patients With Microvascular Decompression Unknown status NCT03152955 Phase 4 Ketamine;ondansetron;Sufentanil
2 Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis Completed NCT03048383 Phase 4 OnabotulinumtoxinA Injectable Product;AbobotulinumtoxinA Injectable Product;Incobotulinumtoxin A Injectable Product
3 Surface Acoustic Wave Ultrasound in Trigeminal Neuralgia Pain Completed NCT01447108 Phase 4
4 Scandinavian Bell's Palsy Study Completed NCT00510263 Phase 4 Prednisolone + placebo;Valaciclovir + placebo;Prednisolone + valaciclovir;Placebo + placebo
5 Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy Recruiting NCT03781700 Phase 4 Prednisolone;Placebo Oral Tablet
6 Oxtellar Extended Release (Oxcarbazepine Extended Release) Patients With Trigeminal Neuralgia Not yet recruiting NCT03374709 Phase 4 Oxtellar XR 150Mg Extended Release Tablet
7 Efficacy and Safety Study of Lamotrigine to Treat Trigeminal Neuralgia Completed NCT00913107 Phase 2, Phase 3 Lamictal®;Tegretol®
8 Corticosteroids in Prevention of Facial Palsy After Cranial Base Surgery Completed NCT00438087 Phase 3 methylprednisolone
9 Botulinum Toxin Injections for Oral Neuropathic Pain Recruiting NCT03555916 Phase 3 BOTOX®, Allergan;Placebo
10 Intratympanic Steroid for Bell's Palsy Recruiting NCT03508440 Phase 2, Phase 3 Prednisone
11 Botulinum Toxin for Trigeminal Neuralgia Recruiting NCT03331913 Phase 3 Botulinum Toxin type A (intradermal / submucosal injection at pain area);Botulinum Toxin type A (intra-masseter injection on the ipsilateral of pain involved)
12 802NP302 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia Not yet recruiting NCT03637387 Phase 3 BIIB074;Placebo
13 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia Not yet recruiting NCT03070132 Phase 3 BIIB074;Placebo
14 A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia Terminated NCT01364259 Phase 3 Amifostine
15 Quadrant Versus Superficial Parotidectomy Withdrawn NCT01607866 Phase 2, Phase 3
16 Efficacy and Safety of ATNC05 in Treatment of Atypical Facial Pain Withdrawn NCT01920087 Phase 2, Phase 3 ATNC05;Placebo
17 Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception Withdrawn NCT00349050 Phase 2, Phase 3
18 Clinical Trial of Hyperbaric Oxygen Treatment in Trigeminal Neuralgia Patients Unknown status NCT00866424 Phase 1, Phase 2
19 Palliative Re-irradiation for Progressive Diffuse Intrinsic Pontine Glioma (DIPG) in Children Completed NCT01777633 Phase 1, Phase 2
20 The Effect of Human Adipose Tissue-derived MSCs in Romberg's Disease Completed NCT01309061 Phase 2
21 Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Trigeminal Neuralgia. Safety Issues. Completed NCT02662972 Phase 1, Phase 2 Botulinum Toxin Type A
22 Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia Completed NCT02473016 Phase 2 Carbon Dioxide Drug Delivery System (CDDS)
23 A Phase IIa Withdrawal Study of CNV1014802 in Patients With Trigeminal Neuralgia Completed NCT01540630 Phase 2 CNV1014802;Placebo
24 Studies of Dextromethorphan and Topiramate to Treat Oral and Facial Pain Completed NCT00001725 Phase 2 Dextromethorphan
25 Trial for Treatment Refractory Trigeminal Neuralgia Recruiting NCT03941834 Phase 2 Rimegepant;Placebo
26 Efficacy of Guanfacine and Lidocaine Combination in Trigeminal Nerve Block for Pain Management in Trigeminal Neuropathy Not yet recruiting NCT03865940 Phase 2 Lidocaine;Guanfacine
27 Glycerol Block of the Trigeminal Ganglion in Trigeminal Neuralgia Using a New Neuronavigation-based Surgical Technique Terminated NCT02624661 Phase 1, Phase 2 Glycerol
28 Botulinum Toxin for the Treatment of Trigeminal Neuralgia Terminated NCT02088632 Phase 2
29 New Formulation and Food Effect Study of BIIB074 Completed NCT02951221 Phase 1 BIIB074 Treatment A;BIIB074 Treatment B;BIIB074 Treatment C;BIIB074 Treatment D
30 PK and Safety Study of BIIB074 in Healthy Japanese and Caucasian Participants Completed NCT02831517 Phase 1 BIIB074;Placebo
31 PK & Tolerability of CNV1014802 in Young and Elderly Healthy Volunteers Completed NCT02359344 Phase 1 CNV1014802;Placebo
32 Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain. Terminated NCT02321566 Phase 1
33 R. I. S. POS. T. A Unknown status NCT01991665 Not Applicable
34 Prednisone and Acupuncture for the Treatment of Facial Neuritis: a Multiple Center, CER in China Unknown status NCT01201642 Not Applicable Prednisolone
35 Autologous Adipose Mesenchymal Stem Cell Transplantation in the Treatment of Patients With Hemifacial Spasm Unknown status NCT02853942 Early Phase 1 Mecobalamin
36 An Evaluation of the Effect of a Surface Acoustic Wave Patch Device on the Symptons of Trigeminal Neuralgia Unknown status NCT02801630 Not Applicable
37 Magnetic Resonance Imaging Study on Patients With Trigeminal Neuralgia Unknown status NCT02713646
38 Role of Mesenchymal Stem Cells in Fat Grafting Unknown status NCT02494752 Not Applicable
39 Treatment of Chronic Myofascial Pain Syndrome Over Neck by Using Intravascular Laser Irradiation of Blood Unknown status NCT02470000 Not Applicable
40 Sensory Retraining Facilitates Sensory Recovery After Mandibular Nerve Injury Unknown status NCT01586598 Not Applicable
41 The Effect of Low Level Laser Therapy (LLLT) in Myofacial Pain Syndrome Unknown status NCT01417637 Not Applicable
42 The Relationship Between Psychological Factors and Bell's Palsy Unknown status NCT01377766
43 A Study of Patient Reported Outcomes After Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia Unknown status NCT01364285
44 Diffusion Tensor Imaging Magnetic Resonance Imaging (DTI MRI) as a Correlate to Pain Relief and Facial Numbness in Patients Following Stereotactic Radiosurgical Rhizotomy for Trigeminal Neuralgia Unknown status NCT01364272
45 Evaluation of Lamotrigine on Neuropathic Facial Pain Using fMRI Completed NCT00243152 Not Applicable Lamotrigine;Placebo (for Lamotrigine)
46 The Role of a Device to Evaluate the Neuromuscular Function in Assessing Muscle in Facial Paralysis Patients Completed NCT02489162 Not Applicable
47 Study of a New Technique to Improve the Symptoms of Orofacial Discomfort in Patients With Peripheral Facial Paralysis Completed NCT01327157 Not Applicable
48 Cognitive Function and Emotional Possessing in Bilateral Facial Palsy Completed NCT02179450
49 MDs on Botox Utility (MOBILITY) Completed NCT00535938
50 A Randomized Trial of Induction Versus Expectant Management Completed NCT01990612 Not Applicable

Search NIH Clinical Center for Geniculate Ganglionitis

Cochrane evidence based reviews: facial nerve diseases

Genetic Tests for Geniculate Ganglionitis

Anatomical Context for Geniculate Ganglionitis

MalaCards organs/tissues related to Geniculate Ganglionitis:

42
Eye, Skin, Liver, Bone, Testes, Cortex, Trigeminal Ganglion

Publications for Geniculate Ganglionitis

Articles related to Geniculate Ganglionitis:

# Title Authors Year
1
Herpes zoster auris (geniculate ganglionitis). ( 21012403 )
1945

Variations for Geniculate Ganglionitis

Expression for Geniculate Ganglionitis

Search GEO for disease gene expression data for Geniculate Ganglionitis.

Pathways for Geniculate Ganglionitis

GO Terms for Geniculate Ganglionitis

Sources for Geniculate Ganglionitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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