Geographic Tongue disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: GGR001 MIFTS: 52	Geographic Tongue Categories: Rare diseases, Gastrointestinal diseases, Oral diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs Download Expand all tables

Sources

Aliases & Classifications for Geographic Tongue

MalaCards integrated aliases for Geographic Tongue:

Name: Geographic Tongue ¹² ⁷⁶ ⁵³ ¹⁵

Glossitis, Benign Migratory ⁴⁴ ⁷³

Benign Migratory Glossitis ¹² ⁵³

Glossitis Areata Exfoliativa ¹²

Erythema Chronicum Migrans ⁷³

Ectopic Geographic Tongue ⁵³

Pityriasis Linguae ¹²

Erythema Migrans ⁵³

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Gastrointestinal diseases Oral diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the digestive system

Diseases of oral cavity, salivary glands and jaws

Diseases of tongue

Geographic tongue

External Ids:

Disease Ontology ¹² DOID:1455

ICD10 ³³ K14.1

ICD9CM ³⁵ 529.1

MeSH ⁴⁴ D005929

NCIt ⁵⁰ C84588

SNOMED-CT ⁶⁸ 155667007 266496009 59032001

UMLS ⁷³ C0017677 C0014740

Sources

Summaries for Geographic Tongue

NIH Rare Diseases : ⁵³ Geographic tongue is a condition that causes chronic and recurrent lesions on the tongue that resemble psoriasis of the skin. It is characterized by pink to red, slightly depressed lesions with irregular, elevated, white or yellow borders. The lesions may also occur in the mucosa of the mouth and labia; this condition is called "areata migrans" because these lesions typically disappear from one area and show up in another. The tongue is normally covered with tiny, pinkish-white bumps (papillae), which are actually short, fine, hair-like projections. With geographic tongue, patches on the surface of the tongue are missing papillae and appear as smooth, red "islands," often with slightly raised borders. These patches (lesions) give the tongue a map-like, or geographic, appearance. In most cases there are no symptoms but sometimes it is painful when inflamed. The cause of this condition is unknown. Many researchers think it is linked with psoriasis, but more research is needed to better understand the connection. Also, hereditary and environmental factors may be involved. The condition is benign and localized, generally requiring no treatment except reassurance. If painful, it may be treated with steroid gels or antihistamine mouth rinses.

MalaCards based summary : Geographic Tongue, also known as glossitis, benign migratory, is related to pustulosis of palm and sole and pustular psoriasis, and has symptoms including exanthema, glossalgia and erythema of the eyelids. An important gene associated with Geographic Tongue is IL36RN (Interleukin 36 Receptor Antagonist), and among its related pathways/superpathways are Class I MHC mediated antigen processing and presentation and Cytokine Signaling in Immune system. The drugs Doxycycline and Penicillin V have been mentioned in the context of this disorder. Affiliated tissues include tongue, skin and testes, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Disease Ontology : ¹² An atrophic glossitis that is characterized as an inflammatory condition of the mucous membrane of the tongue, usually on the dorsal surface.

Wikipedia : ⁷⁶ Geographic tongue, also known by several other terms,[note 1] is an inflammatory condition of the mucous... more...

Sources

Related Diseases for Geographic Tongue

Diseases related to Geographic Tongue via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)

#	Related Disease	Score	Top Affiliating Genes
1	pustulosis of palm and sole	30.0	IL36RN TNF
2	pustular psoriasis	30.0	IL36RN TNF
3	celiac disease 1	27.5	CD79A HLA-A HLA-DQB1 HLA-DQB2 TGM2 TNF
4	lyme disease	11.6
5	fissured tongue	11.5
6	limbic encephalitis with lgi1 antibodies	10.9	HLA-DQB1 HLA-DRB1
7	phenytoin or carbamazepine toxicity	10.8	HLA-A HLA-B
8	recurrent hypersomnia	10.8	HLA-DQB1 HLA-DQB2
9	metal allergy	10.8	HLA-DQB1 HLA-DRB1
10	focal epithelial hyperplasia	10.8	HLA-DQB1 HLA-DRB1
11	hypersomnia	10.8	HLA-DQB1 HLA-DRB1
12	atrial tachyarrhythmia with short pr interval	10.7	HLA-A HLA-B
13	lichen planopilaris	10.7	HLA-DQB1 HLA-DRB1
14	type ii mixed cryoglobulinemia	10.7	HLA-DQB1 HLA-DRB1
15	postherpetic neuralgia	10.6	HLA-A HLA-B HLA-DRB1
16	idiopathic inflammatory myopathy	10.6	HLA-B HLA-DRB1
17	autoimmune hepatitis	10.6	HLA-A HLA-DQB1 HLA-DRB1
18	pars planitis	10.5	HLA-A HLA-B HLA-DRB1
19	atrophic glossitis	10.5	HLA-A HLA-DQB2 IL36RN WHRN
20	glaucomatocyclitic crisis	10.5	HLA-A HLA-B HLA-C
21	histoplasmosis	10.5	HLA-A HLA-B HLA-DRB1
22	pure red-cell aplasia	10.5	HLA-A HLA-B HLA-DRB1
23	acute disseminated encephalomyelitis	10.5	HLA-B HLA-DQB1 HLA-DRB1
24	human herpesvirus 8	10.5	HLA-A HLA-B HLA-C
25	recurrent respiratory papillomatosis	10.4	EGFR HLA-DQB1 HLA-DRB1
26	beryllium disease	10.3	HLA-DQB1 HLA-DRB1 TNF
27	autoimmune pancreatitis	10.3	HLA-DQB1 HLA-DRB1 TNF
28	chronic beryllium disease	10.3	HLA-DQB1 HLA-DRB1 TNF
29	lichen sclerosus	10.3	HLA-DQB1 HLA-DRB1 TNF
30	rheumatic heart disease	10.3	HLA-A HLA-DRB1 TNF
31	vogt-koyanagi-harada disease	10.3	HLA-A HLA-B HLA-DQB1 HLA-DRB1
32	oligoarticular juvenile idiopathic arthritis	10.3	HLA-DQB1 HLA-DRB1 TNF
33	dengue hemorrhagic fever	10.3	HLA-A HLA-DRB1 TNF
34	severe hemophilia a	10.3	HLA-DQB1 HLA-DRB1 TNF
35	sympathetic ophthalmia	10.2	HLA-C HLA-DRB1 TNF
36	aphthous stomatitis	10.2	HLA-A HLA-B TNF
37	microscopic polyangiitis	10.2	HLA-B HLA-DRB1 TNF
38	severe cutaneous adverse reaction	10.2	EPHX1 HLA-A HLA-B HLA-C
39	cytomegalovirus retinitis	10.2	HLA-B HLA-DQB1 TNF
40	melanoma, uveal	10.2	HLA-A HLA-B NME1
41	osteonecrosis of the jaw	10.2	HLA-DQB1 HLA-DRB1 VEGFA
42	anterior uveitis	10.2	HLA-A HLA-B
43	psoriasis	10.1
44	glossitis	10.1
45	leishmaniasis	10.1	HLA-DQB1 HLA-DRB1 TNF
46	cholangitis	10.1	HLA-B HLA-DRB1 TNF
47	rheumatic disease	10.1	HLA-B HLA-DRB1 TNF
48	myocarditis	10.0	HLA-B HLA-DQB1 TNF
49	spondylitis	10.0	HLA-B HLA-C TNF
50	juvenile dermatitis herpetiformis	10.0	CD79A HLA-A

Graphical network of the top 20 diseases related to Geographic Tongue:

Sources

Symptoms & Phenotypes for Geographic Tongue

UMLS symptoms related to Geographic Tongue:

exanthema, glossalgia, erythema of the eyelids, heliotrope rash

GenomeRNAi Phenotypes related to Geographic Tongue according to GeneCards Suite gene sharing:

²⁶ (show all 25)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-103	10.48	HLA-B HLA-C HLA-A
2	Increased shRNA abundance (Z-score > 2)	GR00366-A-11	10.48	CD79A
3	Increased shRNA abundance (Z-score > 2)	GR00366-A-110	10.48	HLA-B HLA-C HLA-A
4	Increased shRNA abundance (Z-score > 2)	GR00366-A-118	10.48	HLA-C HLA-B HLA-A EGFR
5	Increased shRNA abundance (Z-score > 2)	GR00366-A-121	10.48	EGFR
6	Increased shRNA abundance (Z-score > 2)	GR00366-A-124	10.48	HLA-C
7	Increased shRNA abundance (Z-score > 2)	GR00366-A-149	10.48	HLA-C
8	Increased shRNA abundance (Z-score > 2)	GR00366-A-156	10.48	HLA-B HLA-C HLA-A
9	Increased shRNA abundance (Z-score > 2)	GR00366-A-162	10.48	HLA-C
10	Increased shRNA abundance (Z-score > 2)	GR00366-A-177	10.48	CD79A
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-178	10.48	HLA-B HLA-C HLA-A
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-19	10.48	HLA-B HLA-C HLA-A
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-190	10.48	EGFR
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-202	10.48	HLA-C
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-21	10.48	EGFR
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-214	10.48	EGFR
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-31	10.48	HLA-B HLA-C HLA-A
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-43	10.48	EGFR
19	Increased shRNA abundance (Z-score > 2)	GR00366-A-47	10.48	HLA-C
20	Increased shRNA abundance (Z-score > 2)	GR00366-A-63	10.48	CD79A
21	Increased shRNA abundance (Z-score > 2)	GR00366-A-7	10.48	HLA-B HLA-C HLA-A
22	Increased shRNA abundance (Z-score > 2)	GR00366-A-70	10.48	CD79A
23	Increased shRNA abundance (Z-score > 2)	GR00366-A-74	10.48	HLA-B HLA-C HLA-A CD79A
24	Increased shRNA abundance (Z-score > 2)	GR00366-A-85	10.48	EGFR
25	Increased shRNA abundance (Z-score > 2)	GR00366-A-93	10.48	HLA-C

MGI Mouse Phenotypes related to Geographic Tongue:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	liver/biliary system	MP:0005370	9.56	WHRN CD79A EGFR HLA-DQB1 NME1 THEM5
2	neoplasm	MP:0002006	9.17	CD79A EGFR EPHX1 NME1 TGM2 TNF

Sources

Drugs & Therapeutics for Geographic Tongue

Drugs for Geographic Tongue (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Doxycycline

Approved, Investigational, Vet_approved

Phase 4,Not Applicable

564-25-0

54671203

Synonyms:

(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

(4S,4AR,5S,5ar,6R,12as)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

10597-92-9

17086-28-1 (mono-hydrate)

24390-14-5

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)

41411-66-9 (6-epimer, mono-hydrochloride)

564-25-0

5-Hydroxy-a-6-deoxytetracycline

5-Hydroxy-alpha-6-deoxytetracycline

5-hydroxy-α-6-deoxytetracycline

5-Hydroxy-α-6-deoxytetracycline

69935-17-7 (mono-hydrochloride, di-hydrate)

6a-Deoxy-5-oxytetracycline

6alpha-deoxy-5-oxytetracycline

6-alpha-deoxy-5-oxytetracycline

6alpha-Deoxy-5-oxytetracycline

6-alpha-Deoxy-5-oxytetracycline

6-Deoxyoxytetracycline

6-Deoxytetracycline

6α-deoxy-5-oxytetracycline

7164-70-7

7264-10-0

94088-85-4 (calcium salt (1:2))

AB08 (*Fosfatex)

AC1NQXW7

AC1NS4CW

AC1NUYS8

AC1O8PYM

alpha-6-Deoxy-5-hydroxytetracycline

alpha-6-Deoxyoxytetracycline

alpha-Doxycycline

Alti-Doxycycline

Anhydrous doxycycline

Apo-Doxy

Atridox

Azudoxat

BCBcMAP01_000024

BIDD:GT0146

BMY-28689

BPBio1_000951

BSPBio_000863

BSPBio_001936

BU-3839T

C06973

CHEBI:50845

CHEMBL1433

CID5281011

CID5353597

CID5463943

CID6713981

CPD001550033

D07876

DB00254

Deoxymykoin

DivK1c_000345

DMSC (*Fosfatex)

Dossiciclina

Dossiciclina [DCIT]

Doxcycline anhydrous

DOXCYCLINE ANHYDROUS

Doxiciclina

Doxiciclina [INN-Spanish]

Doxiciclina [Italian]

Doxitard

Doxivetin

DOXY

Doxy-Caps

Doxycen

Doxychel

Doxychel (TN)

Doxycin

Doxycyclin

doxycycline

Doxycycline (200mg/day) or Placebo

Doxycycline (anhydrous)

Doxycycline (INN)

Doxycycline (internal use)

Doxycycline (TN)

Doxycycline anhydrous

DOXYCYCLINE CALCIUM

Doxycycline hyclate

Doxycycline monohydrate

DOXYCYCLINE MONOHYDRATE

Doxycycline-Chinoin

Doxycyclinum

Doxycyclinum [INN-Latin]

Doxy-Puren

Doxysol

Doxy-Tabs

Doxytec

Doxytetracycline

EINECS 209-271-1

GS-3065 (*monohydrate)

HMS2090E06

HSDB 3071

Hydramycin

IDI1_000345

Investin

Jenacyclin

KBio1_000345

KBio2_001287

KBio2_003855

KBio2_006423

KBio3_001156

KBioGR_001133

KBioSS_001287

Liviatin

Lopac0_000405

LS-187766

LS-93868

MolPort-002-507-423

Monodox

Monodox (*monohydrate)

NCGC00161602-01

NCGC00161602-03

NCGC00161602-04

NCGC00167961-01

NCGC00179395-01

NINDS_000345

Novo-Doxylin

NSC633557

Nu-Doxycycline

Oracea

Prestwick0_000852

Prestwick1_000852

Prestwick2_000852

Prestwick3_000852

Ronaxan

SAM002589932

SMP1_000107

Spanor

SPBio_000246

SPBio_002784

Spectrum_000807

Spectrum2_000143

Spectrum3_000408

Spectrum4_000527

Spectrum5_000947

STOCK1N-34341

Supracyclin

UNII-334895S862

UPCMLD-DP021

UPCMLD-DP021:001

Vibramycin

Vibramycin (*monohydrate)

Vibramycin Novum

Vibramycine

Vibra-tabs

Vibravenos

Vivox (*Hyclate)

Penicillin V

Approved, Vet_approved

Phase 4

87-08-1

6869

Synonyms:

(2S,5R,6R)-3,3-DIMETHYL-7-oxo-6-(2-phenoxyacetamido)-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylate

(2S,5R,6R)-3,3-DIMETHYL-7-oxo-6-(2-phenoxyacetamido)-4-thia-1- azabicyclo(3.2.0)heptane-2-carboxylIC ACID

(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(phenyloxy)acetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

1098-87-9 (mono-hydrochloride salt)

132-98-9

132-98-9 (mono-potassium salt)

147-48-8 (mono-hydrochloride salt)

2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carbonyl

2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carboxylic acid

3,3-dimethyl-6beta-[(phenoxyacetyl)amino]penam-2alpha-carboxylic acid (PIN)

3,3-Dimethyl-7-oxo-6-((phenyloxyacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid

4-27-00-05884 (Beilstein Handbook Reference)

6-Phenoxyacetamidopenicillanate

6-phenoxyacetamidopenicillanic acid

6-Phenoxyacetamidopenicillanic acid

87-08-1

AB00514745

AC1L1NHG

AC1Q5QX3

Acipen V

acipen-v

Apocillin

Apopen

AR-1H6492

Beepen-VK

Beromycin

Beromycin, penicillin

Beromycin, Penicillin

Berromycin, penicillin

Berromycin, Penicillin

Betapen

Betapen-VK

Bio-0630

BRD-K43966364-237-02-2

BRN 0096259

BSPBio_002185

C08126

C16H18N2O5S

Calcipen

CCRIS 752

CHEBI:27446

CHEBI:53706

CHEMBL615

CID6869

Compocillin V

Crystapen V

D05411

DB00417

DB08415

Distaquaine V

DivK1c_000779

EINECS 201-722-0

Eskacillian V

Eskacillin V

Fenacilin

Fenospen

Fenossimetilpenicillina

Fenossimetilpenicillina [DCIT]

Fenoximetilpenicilina

Fenoximetilpenicilina [INN-Spanish]

Fenoxymethylpenicillin

Fenoxypen

HSDB 6314

IDI1_000779

KBio1_000779

KBio2_001487

KBio2_004055

KBio2_006623

KBio3_001685

KBioGR_000944

KBioSS_001487

LS-1861

Meropenin

MLS001304105

MolPort-002-515-462

NCGC00159342-02

NINDS_000779

Oracillin

Oratren

Ospen

Pen VK

Penapar-Vk

Penicillin beromycin

Penicillin berromycin

Penicillin phenoxymethyl

Penicillin Phenoxymethyl

penicillin v

Penicillin V

Penicillin V (USP)

Penicillin V [USAN]

Penicillin V potassium

Penicillin V sodium

Penicillin VK

Penicillin, phenoxymethyl

Penicillin, Phenoxymethyl

Penicillin-Vk

Pen-Oral

Pen-V

Pen-vee

Phenocillin

Phenomycilline

Phenopenicillin

Phenoximethylpenicillinum

phenoxomethylpenicillanyl

phenoxomethylpenicillin

Phenoxomethylpenicillin

Phenoxymethyl penicillin

Phenoxymethyl Penicillin

Phenoxymethylenepenicillinate

Phenoxymethylenepenicillinic acid

phenoxymethylpenicillanyl

Phenoxymethylpenicillin

Phenoxymethylpenicillin (INN)

Phenoxymethylpenicillin potassium

Phenoxymethylpenicilline

Phénoxyméthylpénicilline

Phenoxymethylpenicilline [INN-French]

phenoxymethylpenicillinic acid

Phenoxymethylpenicillinic acid

Phenoxymethylpenicillinic acid potassium salt

Phenoxymethylpenicillinum

Phenoxymethylpenicillinum [INN-Latin]

P-Mega-Tablinen

PNV

Potassium, penicillin V

PVA

Robicillin

Rocilin

SMR000539431

Sodium, penicillin V

SPBio_000389

Spectrum_001007

Spectrum2_000495

Spectrum3_000543

Spectrum4_000472

Spectrum5_001409

Stabicillin

UNII-Z61I075U2W

V Cillin K

V Sodium, penicillin

V-Cil

V-Cillin

V-Cillin (TN)

VCillin K

V-Cillin K

V-Cylina

V-Cyline

Vebecillin

Vegacillin

V-Tablopen

Cefuroxime

Approved

Phase 4,Not Applicable

55268-75-2

5361202 5479529

Synonyms:

(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[(Carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[(Carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-(2-(2-Furyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid 7(sup 2)-(Z)-(O-methyloxime) carbamate (ester)

153012-39-6

3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid

55268-75-2

56238-63-2

AC-15028

AC1NUIFB

AC1Q41FS

AC-4539

Anaptivan

BIDD:GT0619

Biociclin

Biofuroksym

Bioxima

BPBio1_001033

BRD-K02733959-236-02-8

BRN 5783190

BSPBio_000939

C06894

C08108

C16H15N4O8S.Na

C16H16N4O8S

C4417_FLUKA

C4417_SIGMA

Cefofix

Cefumax

Cefurex

Cefuril

Cefuroxim

Cefuroxim AJ

Cefuroxim curasan

Cefuroxim Fresenius

Cefuroxim Genericsn

Cefuroxim Hexal

Cefuroxim Lilly

Cefuroxim MN

Cefuroxim Norcox

Cefuroxim Norcox [inj.]

Cefuroxima Fabra

Cefuroxima Richet

cefuroxime

Cefuroxime

Cefuroxime (TN)

Cefuroxime (USAN/INN)

Cefuroxime [USAN:INN:BAN]

CEFUROXIME AND DEXTROSE IN DUPLEX CONTAINER

Cefuroxime for Injection and Dextrose for Injection in Duplex Container

cefuroxime na

CEFUROXIME SODIUM

Cefuroxime sodium (JP15/USP)

Cefuroxime sodium [USAN:BAN:JAN]

Cefuroxime sodium salt

cefuroximesodium

Cefuroximine

Cefuroximo

Cefuroximo [INN-Spanish]

Cefuroximum

Cefuroximum [INN-Latin]

Cephuroxime

Cetroxil

Cetroxil [inj.]

CHEBI:3515

CHEMBL1436

CID5479529

CID6523269

Colifossim

CPD0-2069

Curocef

Curoxim

Curoxima

Curoxime

CXM

D00262

D00915

EINECS 259-560-1

EINECS 260-073-1

Froxal

Froxal [inj.]

Furoxil

KEFUROX IN PLASTIC CONTAINER

Kesint

Ketocef

KS-1040

Lifurox

LS-149936

LS-2226

Medoxim

MolPort-002-885-814

MolPort-005-938-003

Prestwick3_000720

Sharox

Sharox [inj.]

Sodium (6R-(6alpha,7beta(Z)))-3-(((aminocarbonyl)oxy)methyl)-7-(2-furyl(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

Sodium (6R,7R)-7-(2-(2-furyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, 7(sup 2)-(Z)-(O-methyloxime), carbamate (ester)

Sodium cefuroxime

Spectrazolr

Ultroxim

UNII-O1R9FJ93ED

UNII-R8A7M9MY61

Zinacef

Zinacef (TN)

Zinacef danmark

Zinacef Danmark

ZINACEF IN PLASTIC CONTAINER

Zinnat [inj.]

Amoxicillin

Approved, Vet_approved

Phase 4,Not Applicable

26787-78-0

33613

Synonyms:

(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid

(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

26787-78-0

33911-69-2

34642-77-8 (mono-hydrochloride salt)

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)

6-(a-amino-4-hydroxyphenylacetamido)Penicillanic acid

6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid

6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin

6-(D-(-)-P-Hydroxy-alpha-aminobenzyl)penicillin

6-(P-Hydroxy-a-aminophenylacetamido)penicillanate

6-(P-Hydroxy-a-aminophenylacetamido)penicillanic acid

6-(P-Hydroxy-alpha-aminophenylacetamido)penicillanate

6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid

6-(P-Hydroxy-alpha-aminophenylacetamido)penicillanic acid

6-(P-Hydroxy-α-aminophenylacetamido)penicillanate

6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid

6-(P-Hydroxy-α-aminophenylacetamido)penicillanic acid

6-[[amino(4-Hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9ci

61336-70-7 (TRIHYDRATE)

6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl

6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid

71447-36-4

81030-75-3

a-amino-P-Hydroxybenzylpenicillin

AC-12263

AC1L1PY2

Actimoxi

Almodan

alpha-amino-P-Hydroxybenzylpenicillin

alpha-Amino-p-hydroxybenzylpenicillin

Ambap26787-78-0

AMC

Amix

Amoclen

Amolin

Amopen

Amopenixin

Amoram

Amox

Amox 250 cap 250MG

Amox 500 cap 500MG

Amox S 125 sus 125mg/5ML

Amox S 250 sus 250mg/5ML

Amoxi

Amoxibiotic

Amoxicaps

Amoxicilina

Amoxicilina [INN-Spanish]

amoxicillanyl

amoxicillin

Amoxicillin

Amoxicillin (anhydrous)

Amoxicillin (INN)

Amoxicillin (TN)

Amoxicillin and clavulanate potassium

Amoxicillin anhydrous

Amoxicillin clariana brand

AMOXICILLIN CRYSTALLINE

Amoxicillin monopotassium salt

Amoxicillin monosodium salt

Amoxicillin pediatric

AMOXICILLIN PEDIATRIC

Amoxicillin sodium

Amoxicillin trihydrate

Amoxicillin Trihydrate

Amoxicillin(usan)

Amoxicillin, (r*)-isomer

Amoxicilline

Amoxicilline [INN]

Amoxicilline [INN-French]

Amoxicillinum

Amoxicillinum [INN-Latin]

Amoxid

Amoxiden

Amoxil

Amoxi-mast

Amoxi-Mast

Amoxivet

Amoxycilin

Amoxycillin

Amoxycillin trihydrate

Amoxycillin Trihydrate

Amoxycillin, ban

Amoxymed

AMPC

Amrit

Anemolin

Anhydrous, amoxicillin

apo-Amoxi

Apo-Amoxi

apo-Amoxi cap 250MG

apo-Amoxi cap 500MG

apo-Amoxi PWR for susp 125mg/5ML

apo-Amoxi PWR for susp 250mg/5ML

apo-Amoxi sugar free

Aspenil

AUGMENTIN '125'

AUGMENTIN '200'

AUGMENTIN '250'

AUGMENTIN '400'

AUGMENTIN '500'

AUGMENTIN '875'

AUGMENTIN es-600

Biomox

BLP 1410

BL-P 1410

BPBio1_000499

BRD-K55044200-001-03-9

Bristamox

BRL 2333

BRL-2333

BSPBio_000453

C06827

Cemoxin

CHEBI:2676

CHEBI:53712

CHEMBL1082

CID33613

Clamoxyl

Clamoxyl (SKB)

Clamoxyl g.a.

Clamoxyl parenteral

Clariana brand OF amoxicillin

CPD000058707

D-(-)-alpha-amino-P-Hydroxybenzyl penicillin

D-(-)-alpha-amino-P-Hydroxybenzylpenicillin

D-(-)-alpha-Amino-p-hydroxybenzylpenicillin

D-(alpha-amino-P-Hydroxybenzyl)penicillin

D07452

D-2-amino-2-(4-Hydroxyphenyl)acetamidopenicillanic acid

D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid

D-Amoxicillin

DB01060

Delacillin

Dispermox

DisperMox

Efpenix

EINECS 248-003-8

Flemoxin

G.A., clamoxyl

Galenamox

Gen-amoxicillin 250MG

Gen-amoxicillin 500MG

Hiconcil

Histocillin

HMS1569G15

HSDB 3204

Hydroxyampicillin

Ibiamox

Imacillin

Lamoxy

Larotid

LS-149721

Metafarma capsules

Metifarma capsules

MLS000028632

MLS002222248

MolPort-003-981-182

MolPort-005-933-687

Moxacin

Moxal

Moxatag

NCGC00179554-01

Novamoxin cap 250MG

Novamoxin cap 500MG

Novamoxin sus 125mg/5ML

Novamoxin sus 250mg/5ML

NSC 277174

NSC277174

Nu-amoxi cap 250MG

Nu-amoxi cap 500MG

Nu-amoxi sus 125/5ML

Nu-amoxi sus 250mg/5ML

Ospamox

Pamoxicillin

Parenteral, clamoxyl

Penamox

Pfizer brand OF amoxicillin sodium salt

PHL-Amoxicillin

p-Hydroxyampicillin

P-Hydroxyampicillin

Piramox

PMS-Amoxicillin

Polymox

Prestwick_713

Prestwick0_000357

Prestwick1_000357

Prestwick2_000357

Prestwick3_000357

Prevpac

pro Amox PWR for oral susp 125mg/5ML

pro Amox-250 cap 250MG

pro Amox-500 cap 500MG

pro-Amox-250 orl sus 250mg/5ML

R-Hydroxyampicillin

Rimoxallin

Ro 10-8756

Robamox

SAM002264592

Sauracillin

Sawamox PM

SmithKline beecham brand OF amoxicillin sodium salt

SMR000058707

Sodium, amoxicillin

SPBio_002374

Sumox

Tolodina

Trihydrate, amoxicillin

Trimox

Unicillin

Utimox

Vetramox

Wymox

Zimox

α-amino-p-hydroxybenzylpenicillin

α-amino-P-hydroxybenzylpenicillin

Anti-Bacterial Agents

Phase 4,Phase 1,Phase 2,Not Applicable

Anti-Infective Agents

Phase 4,Phase 1,Phase 2,Not Applicable

Antiparasitic Agents

Phase 4,Not Applicable

Antiprotozoal Agents

Phase 4,Not Applicable

Antimalarials

Phase 4,Not Applicable

penicillins

Phase 4

cefuroxime axetil

Phase 4,Not Applicable

Antibiotics, Antitubercular

Phase 4,Phase 1,Phase 2,Not Applicable

Ceftriaxone

Approved

Not Applicable

73384-59-5

5479530 5361919

Synonyms:

(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-{[(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-methyloxime), sesquaterhydrate

(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulphanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

104376-79-6

104376-79-6 (di-hydrochloride salt)

73384-59-5

74578-69-1 (di-hydrochloride salt, hemiheptahydrate)

7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid

AC-1592

AC1NUIFE

Anhydrous ceftriaxone sodium

Benaxona

Biotrakson

Boehringer mannheim brand OF ceftriaxone sodium

C06683

C18H18N8O7S3

Cefatriaxone

Cefaxona

Ceftrex

Ceftriaxon

Ceftriaxon curamed

Ceftriaxon hexal

Ceftriaxona

Ceftriaxona [INN-Spanish]

Ceftriaxona andreu

Ceftriaxona LDP torlan

ceftriaxone

Ceftriaxone (INN)

Ceftriaxone (TN)

Ceftriaxone [USAN:JAN]

Ceftriaxone intravenous

Ceftriaxone irex

Ceftriaxone sodium

CEFTRIAXONE SODIUM

Ceftriaxone sodium, anhydrous

Ceftriaxone, disodium salt

Ceftriaxone, Disodium Salt

Ceftriaxone, disodium salt, hemiheptahydrate

Ceftriaxone, Disodium Salt, Hemiheptahydrate

Ceftriaxonum

Ceftriaxonum [INN-Latin]

Ceftriazone

CHEBI:29007

CHEMBL161

CID5479530

Columbia brand OF ceftriaxone

CTRX

Curamed brand OF ceftriaxone sodium

D07659

DB01212

DRG-0071

EINECS 277-405-6

Fustery brand OF ceftriaxone sodium

Galen brand OF ceftriaxone sodium

Hexal brand OF ceftriaxone sodium

Hoffman la roche brand OF ceftriaxone sodium

Hoffman-la roche brand OF ceftriaxone sodium

Inibsa brand OF ceftriaxone sodium

Irex brand OF ceftriaxone

Lendacin

Longacef

Longaceph

LS-150031

MolPort-005-933-495

Pisa brand OF ceftriaxone sodium

Ro 139904

Ro13-9904

Ro-13-9904

Rocefalin

Rocefin

Rocephin

Rocephine

Roche brand OF ceftriaxone sodium

Sodium, ceftriaxone

Syntex brand OF ceftriaxone sodium

Tacex

Terbac

UNII-75J73V1629

Antibodies

Immunoglobulins

Immunoglobulin A

Immunoglobulin G

Immunoglobulin M

Antitubercular Agents

Not Applicable

Interventional clinical trials:

(show all 25)

#	Name	Status	NCT ID	Phase	Drugs
1	Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome	Completed	NCT01518192	Phase 4	doxycycline;cefuroxime axetil
2	Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice	Completed	NCT01368341	Phase 4	Doxycycline;Phenoxymethylpenicillin;Amoxicillin
3	Xenodiagnosis After Antibiotic Treatment for Lyme Disease	Recruiting	NCT02446626	Phase 1, Phase 2
4	The Relationship Between Allergic Rhinitis and Geographic Tongue	Unknown status	NCT01454492
5	Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis	Unknown status	NCT00942006	Not Applicable	doxycycline;ceftriaxone
6	Duration of Antibiotic Treatment of Erythema Migrans	Completed	NCT00910715	Not Applicable	doxycycline;doxycycline;placebo
7	Doxycycline in Therapy of Erythema Migrans	Completed	NCT01475708		Doxycycline
8	Culture Media for Borrelia Burgdorferi Sensu Lato	Completed	NCT02145754	Not Applicable
9	Searching for Persistence of Infection in Lyme Disease	Completed	NCT01143558	Early Phase 1
10	Sofia 2 Lyme FIA Whole Blood Clinical Study	Completed	NCT03238274
11	Cytokines and Chemokines in Erythema Migrans	Recruiting	NCT02147249	Not Applicable	antibiotic treatment
12	Antibiotic Treatment of Multiple Erythema Migrans	Recruiting	NCT01163994	Not Applicable	ceftriaxone;doxycycline
13	Duration of Doxycycline Treatment in EM Patients	Recruiting	NCT03153267	Not Applicable	Doxycycline 100 MG Oral Tablet bid, 7 days;Doxycycline 100 MG Oral Tablet bid, 14 days;Controls without a history of lyme disease.
14	Analysis of Lyme Disease Lesions	Recruiting	NCT00132327
15	Duration of Doxycycline Treatment in MEM Patients	Recruiting	NCT03337932	Not Applicable	Doxycycline 100 milligram Oral Tablet bid, 7 days;Doxycycline 100 milligram Oral Tablet bid, 14 days;Controls without a history of lyme disease.
16	Lyme Borreliosis and Early Cutaneous Diagnostic	Recruiting	NCT02414789	Not Applicable
17	Detection of Borrelia Bacteria in Early Stage Lyme Borreliosis Using the T2Lyme Panel	Recruiting	NCT03581279	Not Applicable
18	Borrelia Species in Cutaneous Lyme Borreliosis	Recruiting	NCT00576082
19	Lyme Test Indication Combinations (LyTIC) Study	Recruiting	NCT03201042
20	Erythema Migrans in Elderly	Active, not recruiting	NCT03371563		Antibiotics
21	Patient's Pretreatment Expectations About Post-Lyme Symptoms	Not yet recruiting	NCT03462329	Not Applicable	Antibiotics (preferentially oral doxycycline 100 mg bid)
22	Next Generation Sequencing Detection of Lyme Disease	Not yet recruiting	NCT03505879
23	Understanding Tick-borne Diseases	Not yet recruiting	NCT03501407
24	Investigation of Southern Tick-Associated Rash Illness (STARI)	Terminated	NCT00358761
25	A Multicenter Study to Evaluate a Borrelia Diagnostic Test in Subjects With Early Stage or Late Stage Lyme Disease	Terminated	NCT02741609	Not Applicable

Search NIH Clinical Center for Geographic Tongue

Cochrane evidence based reviews: glossitis, benign migratory

Sources

Genetic Tests for Geographic Tongue

Sources

Anatomical Context for Geographic Tongue

MalaCards organs/tissues related to Geographic Tongue:

⁴¹

Tongue, Skin, Testes, Whole Blood

Sources

Publications for Geographic Tongue

Articles related to Geographic Tongue:

(show top 50) (show all 57)

#	Title	Authors	Year
1	An infant with generalized pustular psoriasis and geographic tongue had a heterozygous IL36RN mutation and IgG2 deficiency. ( 29454537 )	Oi R....Akiyama M.	2018
2	Acrodermatitis continua of Hallopeau and geographic tongue are variants of pustular psoriasis. ( 29687071 )	Sadlier M.	2018
3	Geographic tongue: Predisposing factors, diagnosis and treatment. A systematic review. ( 29903400 )	GonzA!lez-A8lvarez L....Garcia-Martin J.M.	2018
4	Geographic tongue: assessment of peripheral nerve status, Langerhans cell, and HLA-DR expression. ( 28757081 )	Darling M.R....Grushka M.	2017
5	Geographic Tongue. ( 28716459 )	Chaubal T....Bapat R.	2017
6	Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis. ( 28188609 )	Picciani B....Dias E.	2017
7	Salivary levels of interleukin-8 and growth factors are modulated in patients with geographic tongue. ( 28178402 )	Dafar A....A8evik-Aras H.	2017
8	Lingual microbiota profiles of patients with geographic tongue. ( 28839519 )	Dafar A....SjAPberg F.	2017
9	IMAGES IN CLINICAL MEDICINE. Geographic Tongue. ( 26886524 )	Varoni E....Decani S.	2016
10	Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review. ( 27579734 )	Picciani B.L....Carneiro S.	2016
11	Oral medicine: Factors associated with geographic tongue and fissured tongue. ( 27388082 )		2016
12	The prevalence of celiac disease in patients with geographic tongue. ( 27131886 )	Cigic L....Biocina Lukenda D.	2016
13	Geographic Tongue. ( 27436616 )	Bakshi S.S....Bhattacharjee S.	2016
14	Paediatric Geographic Tongue: A Case Report, Review and Recent Updates. ( 27042597 )	Nandini D.B....Ashwini R.	2016
15	Geographic tongue associated with sialadenitis. ( 27726175 )	Ikeda A....Yamamoto O.	2016
16	Geographic tongue. ( 27505875 )	Jacob C.N....R J.	2016
17	Treatment of Symptomatic Geographic Tongue with Triamcinolone Acetonide Alone and in Combination with Retinoic Acid: A Randomized Clinical Trial. ( 27536325 )	Najafi S....Kharrazifard M.J.	2016
18	Mutations in IL36RN are associated with geographic tongue. ( 27900482 )	Liang J....Yao Z.	2016
19	Factors associated with geographic tongue and fissured tongue. ( 26381370 )	Dafar A....Jontell M.	2015
20	Prevalence of Geographic tongue and Related Predisposing Factors in 7-18 Year-Old Students in Kermanshah, Iran 2014. ( 26156909 )	Rezaei F....Tavakoli P.	2015
21	Geographic tongue and fissured tongue in 348 patients with psoriasis: correlation with disease severity. ( 25685842 )	Picciani B.L....Dias E.P.	2015
22	Psychological parameters associated with geographic tongue: a clinical observation. ( 25482552 )	Khalighinejad N....Gorsky M.	2015
23	Psychological parameters associated with geographic tongue: a clinical observation. ( 25482551 )	Stoopler E.T....Sollectio T.P.	2015
24	A possible relationship of human leucocyte antigens with psoriasis vulgaris and geographic tongue. ( 25176018 )	Picciani B.L....Dias E.P.	2014
25	Medical image. A benign glossal lesion. Geographic tongue. ( 24929575 )	Gupta T....Kansal N.K.	2014
26	Relation between psoriasis and geographic tongue. ( 25584342 )	Tarakji B....Sarraj F.	2014
27	Treatment of geographic tongue with topical tacrolimus. ( 25085945 )	Purani J.M....Purani H.J.	2014
28	Immunologic and psychologic parameters associated with geographic tongue. ( 24842481 )	Alikhani M....Gorsky M.	2014
29	Case of the month. Ectopic geographic tongue (erythema migrans). ( 24937889 )	Kacher J.E.	2014
30	Geographic tongue in monozygotic twins. ( 24959517 )	Shekhar M G.	2014
31	Geographic tongue induced by angiogenesis inhibitors. ( 23576484 )	Hubiche T....Sibaud V.	2013
32	Geographic tongue and tenofovir. ( 23598934 )	Ferreira A.O....Costa J.B.	2013
33	Geographic Tongue and Associated Risk Factors among Iranian Dental Patients. ( 23515238 )	Honarmand M....Sehhatpour M.	2013
34	Oral and maxillofacial pathology case of the month. Erythema migrans (ectopic migratory glossitis/ectopic geographic tongue). ( 24236384 )	Raja R....Vigneswaran N.	2013
35	The comparison of salivary level of estrogen and progesterone in 1(st) , 2(nd) and 3(rd) trimester in pregnant women with and without geographic tongue. ( 24348617 )	Ghalayani P....Khalighinejad N.	2013
36	Increased prevalence of geographic tongue in burning mouth complaints: a retrospective study. ( 22901641 )	Ching V....Su N.	2012
37	Migratory stomatitis (ectopic geographic tongue) on the floor of the mouth. ( 21763590 )	Zadik Y....Pallmon S.	2011
38	Geographic tongue treated with topical tacrolimus. ( 21886753 )	Ishibashi M....Aiba S.	2010
39	Images in clinical medicine. Geographic tongue. ( 19907039 )	Masferrer E....JucglA A.	2009
40	Allergic contact stomatitis presenting as geographical tongue with pruritus. ( 19207382 )	Waroquier D....Parent D.	2009
41	Oral medicine case book 7. Migratory stomatitis and geographic tongue. ( 18689340 )	Dreyer W.P....de Waal J.	2008
42	Recurrent geographical tongue and fissured tongue in association with pregnancy. ( 17243991 )	Yun S.J....Lee S.C.	2007
43	Ectopic geographic tongue--a case report. ( 17432777 )	Borrie F....Macintyre D.	2007
44	Prevalence and risk factors associated with geographic tongue among US adults. ( 16792723 )	Shulman J.D....Carpenter W.M.	2006
45	The prevalence and significance of fissured tongue and geographical tongue in psoriatic patients. ( 16487088 )	Zargari O.	2006
46	Geographic tongue: clinical characteristics of 188 cases. ( 15719084 )	Jainkittivong A....Langlais R.P.	2005
47	Geographic tongue: literature review and case reports. ( 16161818 )	Pass B....Childers E.L.	2005
48	Painful geographic tongue (benign migratory glossitis) in a child. ( 15482313 )	Menni S....Crosti C.	2004
49	Prevalence of fissured tongue, geographic tongue and median rhomboid glossitis among Israeli adults of different ethnic origins. ( 15316160 )	Yarom N....Gorsky M.	2004
50	Benign migratory glossitis or geographic tongue: an enigmatic oral lesion. ( 12517366 )	Assimakopoulos D....Elisaf M.	2002

Sources

Genes for Geographic Tongue

Genes related to Geographic Tongue (0 elite genes):

(show all 18)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	IL36RN	Interleukin 36 Receptor Antagonist	Protein Coding	23.61	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
2	HLA-A	Major Histocompatibility Complex, Class I, A	Protein Coding	15.35	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	WHRN	Whirlin	Protein Coding	15.3	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
4	HLA-DQB2	Major Histocompatibility Complex, Class II, DQ Beta 2	Protein Coding	15.09	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
5	HLA-DQB1	Major Histocompatibility Complex, Class II, DQ Beta 1	Protein Coding	14.98	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
6	AKTIP	AKT Interacting Protein	Protein Coding	14.66	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
7	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	14.46	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
8	EPHX1	Epoxide Hydrolase 1	Protein Coding	14.41	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
9	HLA-C	Major Histocompatibility Complex, Class I, C	Protein Coding	14.26	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
10	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	13.86	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
11	HLA-B	Major Histocompatibility Complex, Class I, B	Protein Coding	13.81	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
12	TNFRSF10B	TNF Receptor Superfamily Member 10b	Protein Coding	13.61	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
13	TGM2	Transglutaminase 2	Protein Coding	13.56	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
14	EGFR	Epidermal Growth Factor Receptor	Protein Coding	13.24	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
15	TNF	Tumor Necrosis Factor	Protein Coding	13.23	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
16	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	13.13	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
17	CD79A	CD79a Molecule	Protein Coding	13.1	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
18	THEM5	Thioesterase Superfamily Member 5	Protein Coding	5.26	DISEASES inferred ¹⁵

Sources

Variations for Geographic Tongue

Sources

Expression for Geographic Tongue

Search GEO for disease gene expression data for Geographic Tongue.

Sources

Pathways for Geographic Tongue

Pathways related to Geographic Tongue according to GeneCards Suite gene sharing:

(show all 24)

#	Super pathways	Score	Top Affiliating Genes
1	Class I MHC mediated antigen processing and presentation ⁶⁶ Show member pathways Adaptive Immune System ⁶⁶ Antigen processing- Ubiquitination and Proteasome degradation ⁶⁶	13.34	CD79A EGFR HLA-A HLA-B HLA-C HLA-DQB1
2	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.17	EGFR HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2
3	PI3K-Akt signaling pathway ³⁷ Show member pathways Human papillomavirus infection ³⁷	12.87	EGFR HLA-A HLA-B HLA-C TNF VEGFA
4	Actin Nucleation by ARP-WASP Complex ⁶⁴ Show member pathways Actin Nucleation and Branching ⁶⁴ CDC42 Pathway ⁶⁴ RhoA Pathway ⁶⁴	12.8	EGFR HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1
5	Regulation of IFNA signaling ⁶⁶ Show member pathways Cytokine Network ⁶⁴ Immune response IFN alpha/beta signaling pathway ²² Interferon alpha/beta signaling ⁶⁶ Interleukin-19, 20, 22, 24 ⁶⁶ Jak/STAT Signaling Pathway ⁶⁵ Jak-STAT signaling pathway ³⁷	12.52	EGFR HLA-A HLA-B HLA-C TNF
6	Immune response NFAT in immune response ²² Show member pathways Immune response CD28 signaling ²² Immune response ICOS pathway in T-helper cell ²² Immune response T cell receptor signaling pathway ²²	12.45	CD79A HLA-DQB1 HLA-DQB2 HLA-DRB1
7	Kaposi's sarcoma-associated herpesvirus infection ³⁷ Show member pathways Hepatitis B ³⁷	12.45	HLA-A HLA-B HLA-C TNF VEGFA
8	Influenza A ³⁷ Show member pathways Herpes simplex infection ³⁷ Measles ³⁷	12.39	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1 TNF
9	Immune response Role of DAP12 receptors in NK cells ²² Show member pathways Immune response CD16 signaling in NK cells ²² Natural killer cell mediated cytotoxicity ³⁷	12.38	HLA-A HLA-B HLA-C TNF TNFRSF10B
10	Interferon gamma signaling ⁶⁶ Show member pathways Interferon Signaling ⁶⁶ Regulation of IFNG signaling ⁶⁶	12.29	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1
11	Endocytosis ³⁷	12.27	EGFR HLA-A HLA-B HLA-C
12	Epstein-Barr virus infection ³⁷	12.13	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1
13	Immune response Antigen presentation by MHC class II ²² Show member pathways G-protein signaling N-RAS regulation pathway ²² IL-22 Pathway ⁶⁴ Immune response IL-22 signaling pathway ²²	12.03	HLA-DQB1 HLA-DQB2 HLA-DRB1
14	Allograft rejection ¹ ³⁷ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	11.97	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1
15	Phagosome ³⁷	11.95	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1
16	HTLV-I infection ³⁷	11.84	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1 TNF
17	S-1P Stimulated Signaling ⁶⁴	11.83	EGFR HLA-DQB1 HLA-DQB2 HLA-DRB1
18	Translocation of ZAP-70 to Immunological synapse ⁶⁶ Show member pathways Generation of second messenger molecules ⁶⁶ PD-1 signaling ⁶⁶ Phosphorylation of CD3 and TCR zeta chains ⁶⁶	11.82	HLA-DQB1 HLA-DQB2 HLA-DRB1
19	Cell adhesion molecules (CAMs) ³⁷	11.81	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1
20	MHC class II antigen presentation ⁶⁶	11.79	HLA-DQB1 HLA-DQB2 HLA-DRB1
21	Hematopoietic cell lineage ³⁷	11.76	HLA-DQB1 HLA-DRB1 TNF
22	Rheumatoid arthritis ³⁷	11.71	HLA-DQB1 HLA-DRB1 TNF VEGFA
23	Aryl Hydrocarbon Receptor ¹	11.43	EGFR TNF VEGFA
24	Antigen Presentation- Folding, assembly and peptide loading of class I MHC ⁶⁶	11.05	HLA-A HLA-B HLA-C

Sources

GO Terms for Geographic Tongue

Cellular components related to Geographic Tongue according to GeneCards Suite gene sharing:

(show all 17)

#	Name	GO ID	Score	Top Affiliating Genes
1	Golgi membrane	GO:0000139	9.87	EGFR HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2
2	endosome membrane	GO:0010008	9.83	EGFR HLA-DQB1 HLA-DQB2 HLA-DRB1
3	early endosome membrane	GO:0031901	9.76	EGFR HLA-A HLA-B HLA-C
4	cell surface	GO:0009986	9.76	EGFR HLA-A HLA-B HLA-C HLA-DRB1 TNF
5	trans-Golgi network membrane	GO:0032588	9.73	HLA-DQB1 HLA-DQB2 HLA-DRB1
6	recycling endosome membrane	GO:0055038	9.72	HLA-A HLA-B HLA-C
7	phagocytic vesicle membrane	GO:0030670	9.71	HLA-A HLA-B HLA-C
8	endocytic vesicle membrane	GO:0030666	9.69	HLA-DQB1 HLA-DQB2 HLA-DRB1
9	transport vesicle membrane	GO:0030658	9.67	HLA-DQB1 HLA-DQB2 HLA-DRB1
10	clathrin-coated endocytic vesicle membrane	GO:0030669	9.58	HLA-DQB1 HLA-DQB2 HLA-DRB1
11	MHC class II protein complex	GO:0042613	9.54	HLA-DQB1 HLA-DQB2 HLA-DRB1
12	MHC class I protein complex	GO:0042612	9.43	HLA-A HLA-B HLA-C
13	ER to Golgi transport vesicle membrane	GO:0012507	9.43	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1
14	integral component of lumenal side of endoplasmic reticulum membrane	GO:0071556	9.1	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1
15	membrane	GO:0016020	10.41	AKTIP CD79A EGFR EPHX1 HLA-A HLA-B
16	plasma membrane	GO:0005886	10.25	AKTIP CD79A EGFR HLA-A HLA-B HLA-C
17	endoplasmic reticulum	GO:0005783	10.08	EGFR EPHX1 HLA-A HLA-B HLA-C HLA-DQB2

Biological processes related to Geographic Tongue according to GeneCards Suite gene sharing:

(show all 20)

#	Name	GO ID	Score	Top Affiliating Genes
1	immune system process	GO:0002376	9.87	CD79A HLA-A HLA-B HLA-C HLA-DQB2 HLA-DRB1
2	immune response	GO:0006955	9.81	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1
3	positive regulation of protein phosphorylation	GO:0001934	9.78	AKTIP EGFR TNF VEGFA
4	antigen processing and presentation of exogenous peptide antigen via MHC class II	GO:0019886	9.77	HLA-DQB1 HLA-DQB2 HLA-DRB1
5	positive regulation of peptidyl-serine phosphorylation	GO:0033138	9.76	EGFR TNF VEGFA
6	T cell costimulation	GO:0031295	9.75	HLA-DQB1 HLA-DQB2 HLA-DRB1
7	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	GO:0002479	9.74	HLA-A HLA-B HLA-C
8	type I interferon signaling pathway	GO:0060337	9.73	HLA-A HLA-B HLA-C
9	positive regulation of MAP kinase activity	GO:0043406	9.72	EGFR TNF VEGFA
10	positive regulation of epithelial cell proliferation	GO:0050679	9.71	EGFR NME1 VEGFA
11	positive regulation of smooth muscle cell proliferation	GO:0048661	9.7	EGFR TGM2 TNF
12	positive regulation of cell adhesion	GO:0045785	9.63	TGM2 TNF VEGFA
13	antigen processing and presentation of peptide antigen via MHC class I	GO:0002474	9.58	HLA-A HLA-B HLA-C
14	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	GO:0002504	9.54	HLA-DQB1 HLA-DQB2 HLA-DRB1
15	protection from natural killer cell mediated cytotoxicity	GO:0042270	9.51	HLA-A HLA-B
16	humoral immune response mediated by circulating immunoglobulin	GO:0002455	9.49	HLA-DQB1 HLA-DRB1
17	immunoglobulin production involved in immunoglobulin mediated immune response	GO:0002381	9.43	HLA-DQB1 HLA-DRB1
18	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	GO:0002480	9.43	HLA-A HLA-B HLA-C
19	interferon-gamma-mediated signaling pathway	GO:0060333	9.43	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1
20	antigen processing and presentation	GO:0019882	9.1	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DQB2 HLA-DRB1

Molecular functions related to Geographic Tongue according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	MHC class II receptor activity	GO:0032395	9.13	HLA-DQB1 HLA-DQB2 HLA-DRB1
2	peptide antigen binding	GO:0042605	9.02	HLA-A HLA-B HLA-C HLA-DQB1 HLA-DRB1
3	protein binding	GO:0005515	10.06	AKTIP CD79A EGFR HLA-A HLA-B HLA-C

Sources

Sources for Geographic Tongue

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia