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MCID: GTR001
MIFTS: 31

Geotrichosis

Categories: Infectious diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Geotrichosis

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MalaCards integrated aliases for Geotrichosis:

Name: Geotrichosis 12 43 15 17 71 32

Classifications:

MalaCards categories:
Global: Infectious diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:2832
MeSH 43 D005847
SNOMED-CT 67 13969006
ICD10 32 B48.3
UMLS 71 C0017455
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Summaries for Geotrichosis

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Disease Ontology : 12 An opportunistic mycosis that has material basis in Galactomyces geotrichum, results in systemic infection in immunocompromised people.

MalaCards based summary : Geotrichosis is related to fungal infectious disease and oral candidiasis. An important gene associated with Geotrichosis is JAK3 (Janus Kinase 3), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Th17 cell differentiation. Affiliated tissues include lung, skin and tonsil, and related phenotypes are endocrine/exocrine gland and hematopoietic system

Wikipedia : 74 Geotrichosis is a mycosis caused by Geotrichum... more...

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Related Diseases for Geotrichosis

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Diseases related to Geotrichosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 87)
# Related Disease Score Top Affiliating Genes
1 fungal infectious disease 30.1 STAT1 CD4
2 oral candidiasis 29.9 STAT1 CD4
3 candidiasis 10.4
4 aspergillosis 10.3
5 neutropenia 10.2
6 pulmonary tuberculosis 10.2
7 pemphigus 10.2
8 alopecia universalis congenita 10.2 JAK3 CD4
9 adenosine deaminase deficiency 10.2 JAK3 CD4
10 splenic sequestration 10.2 CYGB CD4
11 t-cell adult acute lymphocytic leukemia 10.2 JAK3 CD4
12 cystoisosporiasis 10.1 CD4 CARTPT
13 esophageal candidiasis 10.1 CD4 CARTPT
14 retinitis pigmentosa 46 10.1 HUWE1 CD4
15 tick infestation 10.1 HUWE1 CD4
16 babesiosis 10.1 HUWE1 CD4
17 fungal meningitis 10.1 CD4 CARTPT
18 inclusion body myopathy with early-onset paget disease of bone with or without frontotemporal dementia 2 10.1 HUWE1 CD4
19 hypophosphatasia, infantile 10.1 CD4 CARTPT
20 asthma 10.1
21 trichosporonosis 10.1
22 cryptococcosis 10.1
23 acute leukemia 10.1
24 acute cystitis 10.1
25 chromoblastomycosis 10.1
26 iron metabolism disease 10.1
27 cystic kidney disease 10.1
28 lung benign neoplasm 10.1
29 folliculitis 10.1
30 adenoma 10.1
31 parathyroid adenoma 10.1
32 myeloid leukemia 10.1
33 rubella 10.1
34 miliary tuberculosis 10.1
35 granulocytopenia 10.1
36 quinquaud folliculitis decalvans 10.1
37 anus cancer 10.1 CD4 CARTPT
38 pneumocystosis 10.1 CD4 CARTPT
39 cytomegalovirus retinitis 10.1 CD4 CARTPT
40 actinomycosis 10.0 HUWE1 CD4
41 inclusion body myopathy with early-onset paget disease of bone with or without frontotemporal dementia 1 10.0 HUWE1 CD4
42 central nervous system hematologic cancer 10.0 CD4 CARTPT
43 cryptosporidiosis 10.0 HUWE1 CD4
44 cryptococcal meningitis 10.0 CD4 CARTPT
45 parasitic ectoparasitic infectious disease 10.0 HUWE1 CD4
46 macs syndrome 10.0 STAT1 CD4
47 coccidiosis 10.0 CD4 CARTPT
48 coccidioidomycosis 10.0 STAT1 CD4
49 bare lymphocyte syndrome, type ii 10.0 JAK3 CD4
50 dysentery 10.0 HUWE1 CD4

Graphical network of the top 20 diseases related to Geotrichosis:



Diseases related to Geotrichosis
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Symptoms & Phenotypes for Geotrichosis

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MGI Mouse Phenotypes related to Geotrichosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.7 CARTPT CD4 CD40 CYGB HUWE1 JAK3
2 hematopoietic system MP:0005397 9.43 CARTPT CD4 CD40 HUWE1 JAK3 STAT1
3 immune system MP:0005387 9.1 CARTPT CD4 CD40 HUWE1 JAK3 STAT1
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Drugs & Therapeutics for Geotrichosis

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Search Clinical Trials , NIH Clinical Center for Geotrichosis

Cochrane evidence based reviews: geotrichosis

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Genetic Tests for Geotrichosis

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Anatomical Context for Geotrichosis

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MalaCards organs/tissues related to Geotrichosis:

40
Lung, Skin, Tonsil
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Publications for Geotrichosis

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Articles related to Geotrichosis:

(show top 50) (show all 75)
# Title Authors PMID Year
1
Geotrichosis Presenting As Funguria and Asymptomatic Urinary Tract Infection in a Patient with Renal Cyst. 61
32399350 2020
2
Geotrichum capitatum septicemia: case report and review of the literature. 61
25681053 2015
3
[Pulmonary infection by Geotrichum capitatum about a case and review of the literature]. 61
25458367 2014
4
Opportunistic yeast infections: candidiasis, cryptococcosis, trichosporonosis and geotrichosis. 61
23621330 2013
5
Epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignancies. 61
23111539 2012
6
Tonsillitis in a weaner pig associated with Geotrichum candidum. 61
21217055 2011
7
Oral geotrichosis: report of 12 cases. 61
20881343 2010
8
Safety assessment of dairy microorganisms: Geotrichum candidum. 61
17869364 2008
9
A case of oral geotrichosis caused by Geotrichum capitatum in an old patient. 61
17881872 2007
10
Intra-species chromosome-length polymorphism in Geotrichum candidum revealed by pulsed field gel electrophoresis. 61
12038569 2002
11
Cutaneous geotrichosis in a dog. 61
10561789 1999
12
[Geotrichosis]. 61
10201236 1999
13
Isolation and identification of Geotrichum candidum as an etiologic agent of geotrichosis in Bulgaria. 61
10371798 1998
14
[Secondary active-evolutive cavitary pulmonary tuberculosis of the apicodorsal segment of the left upper lobe associated with bronchial tuberculosis and bronchial geotrichosis]. 61
9567625 1997
15
Geotrichosis of oral mucosa. 61
9009647 1996
16
[Intestinal geotrichosis]. 61
7837530 1994
17
[Intestinal geotrichosis]. 61
7736102 1994
18
Oral Geotrichum candidum infection associated with HIV infection. A case report. 61
1437044 1992
19
Oral mycoses in HIV infection. 61
1549312 1992
20
Pulmonary geotrichosis. 61
1570261 1992
21
A case of hitherto unreported cutaneous geotrichosis from India. 61
1452249 1992
22
Disseminated geotrichosis in two dogs. 61
2391272 1990
23
[Invasive fungal infections in hematologic malignancies--a retrospective study of 61 autopsied cases]. 61
2366325 1990
24
Cutaneous Chromomycosis with Pulmonary Geotrichosis. 61
28128150 1989
25
[General review of mycoses affecting the maxillofacial area]. 61
2678959 1989
26
[General review of maxillofacial mycoses]. 61
2577745 1989
27
Geotrichosis: who is susceptible? 61
3191781 1988
28
[Pathologic changes of the hair and nails in generalized geotrichosis]. 61
3507728 1986
29
Association of anurans with pathogenic fungi. 61
4069190 1985
30
Pulmonary geotrichosis. 61
6618526 1983
31
Mycotic infections of the alimentary tract of nonhuman primates: a review. 61
6815875 1982
32
Mycotic infections of the alimentary tract of nonhuman primates: a review. 61
6153014 1982
33
Drugs for fungal infections. 61
6893517 1980
34
Cutaneous and renal geotrichosis in a giant tortoise (Geochelone elephantopus). 61
7368044 1980
35
[Geotrichosis of the respiratory tract associated with non-specific skin changes]. 61
463007 1979
36
Gastrointestinal geotrichosis in six adult gorillas. 61
924882 1977
37
[Systemic mycoses. 4. Systemic mycoses caused by molds (aspergillosis, geotrichosis)]. 61
1010519 1976
38
Cutaneous geotrichosis in the red flamingo (Phoenicopterus ruber). 61
1265572 1976
39
Geotrichum septicemia. 61
814251 1976
40
Bronchopulmonary geotrichosis. 61
1233353 1975
41
Bronchopulmonary geotrichosis. 61
4796160 1973
42
[Geotrichosis of oral mucosa in the course of pemphigus treated with large doses of glucocorticoids]. 61
5062245 1972
43
[Cured pulmonary geotrichosis in a patient with a history of familial lung neoplasms]. 61
5160976 1971
44
Pulmonary geotrichosis and candidiasis. 61
5113696 1971
45
[A case of geotrichosis in the stump of a resected bronchus after pneumonectomy]. 61
5143439 1971
46
Bronchial geotrichosis with fungemia complicating bronchogenic carcinoma. 61
5099817 1971
47
[Geotrichosis of the urinary system and the alimentary tract in a patient with pemphigus treated protractedly with glucocorticosteroids]. 61
5482559 1970
48
Fungal superinfection: geotrichosis of the urinary tract in association with parathyroid adenoma. 61
4872500 1968
49
Disseminated geotrichosis in a dog. 61
5749201 1968
50
[A case of acute geotrichosis of the oral mucosa]. 61
5234784 1967
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Variations for Geotrichosis

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Expression for Geotrichosis

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Search GEO for disease gene expression data for Geotrichosis.
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Pathways for Geotrichosis

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Pathways related to Geotrichosis according to GeneCards Suite gene sharing:

(show all 13)
# Super pathways Score Top Affiliating Genes
1
Cytokine Signaling in Immune system 65
Show member pathways
 12.93 STAT1 JAK3 CD40 CD4
2
Th17 cell differentiation 36
Show member pathways
 12.19 STAT1 JAK3 CD4
3
4-1BB Pathway 63
Show member pathways
 11.85 STAT1 JAK3 CD40 CD4
4
Human T-cell leukemia virus 1 infection 36
11.77 JAK3 CD40 CD4
5
Jak Stat Signaling Pathway 66
Show member pathways
 11.72 STAT1 JAK3
6
CXCR4-mediated signaling events 1
11.39 STAT1 CD4
7
Th17 Differentiation 64
Show member pathways
 11.29 STAT1 JAK3 CD4
8
Th2 Differentiation 64
11.12 JAK3 CD4
9
IL-7 Signaling Pathway 1
Show member pathways
 11.08 STAT1 JAK3
10
Signaling events mediated by TCPTP 1
Show member pathways
 11.03 STAT1 JAK3
11
CD40/CD40L signaling 1
10.85 JAK3 CD40
12
IL10 Signaling Pathway 66
10.78 JAK3 CD40
13
Primary immunodeficiency 36
10.38 JAK3 CD40 CD4
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GO Terms for Geotrichosis

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Biological processes related to Geotrichosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.5 STAT1 JAK3 CD4
2 circadian regulation of gene expression GO:0032922 9.4 HUWE1 CARTPT
3 positive regulation of T cell proliferation GO:0042102 9.37 JAK3 CD4
4 interleukin-15-mediated signaling pathway GO:0035723 9.26 JAK3 CD4
5 interleukin-9-mediated signaling pathway GO:0038113 9.16 STAT1 JAK3
6 interleukin-21-mediated signaling pathway GO:0038114 8.96 STAT1 JAK3
7 enzyme linked receptor protein signaling pathway GO:0007167 8.62 JAK3 CD4

Molecular functions related to Geotrichosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 8.8 STAT1 CD40 CD4
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Sources for Geotrichosis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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