MCID: GTR001
MIFTS: 30

Geotrichosis

Categories: Infectious diseases

Aliases & Classifications for Geotrichosis

MalaCards integrated aliases for Geotrichosis:

Name: Geotrichosis 12 43 15 17 71 32

Classifications:



External Ids:

Disease Ontology 12 DOID:2832
MeSH 43 D005847
SNOMED-CT 67 13969006
ICD10 32 B48.3
UMLS 71 C0017455

Summaries for Geotrichosis

Disease Ontology : 12 An opportunistic mycosis that has material basis in Galactomyces geotrichum, results in systemic infection in immunocompromised people.

MalaCards based summary : Geotrichosis is related to oral candidiasis and candidiasis. An important gene associated with Geotrichosis is JAK3 (Janus Kinase 3), and among its related pathways/superpathways are Akt Signaling and Cytokine Signaling in Immune system. Affiliated tissues include lung, skin and tonsil, and related phenotype is endocrine/exocrine gland.

Wikipedia : 74 Geotrichosis is a mycosis caused by Geotrichum... more...

Related Diseases for Geotrichosis

Diseases related to Geotrichosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 80)
# Related Disease Score Top Affiliating Genes
1 oral candidiasis 29.6 STAT1 CD4
2 candidiasis 10.4
3 aspergillosis 10.3
4 neutropenia 10.2
5 pulmonary tuberculosis 10.2
6 pemphigus 10.2
7 asthma 10.1
8 trichosporonosis 10.1
9 cryptococcosis 10.1
10 acute leukemia 10.1
11 chromoblastomycosis 10.1
12 iron metabolism disease 10.1
13 lung benign neoplasm 10.1
14 folliculitis 10.1
15 adenoma 10.1
16 parathyroid adenoma 10.1
17 rubella 10.1
18 miliary tuberculosis 10.1
19 granulocytopenia 10.1
20 quinquaud's decalvans folliculitis 10.1
21 immunodeficiency 19 10.0 JAK3 CD4
22 viral esophagitis 10.0 JAK3 CD4
23 t-cell adult acute lymphocytic leukemia 10.0 JAK3 CD4
24 splenic sequestration 10.0 CYGB CD4
25 cystoisosporiasis 10.0 CD4 CARTPT
26 barbiturate abuse 10.0 CD4 CARTPT
27 esophageal candidiasis 10.0 CD4 CARTPT
28 fungal meningitis 10.0 CD4 CARTPT
29 immunodeficiency with hyper-igm, type 3 10.0 CD40 CD4
30 hypophosphatasia, infantile 9.9 CD4 CARTPT
31 anus cancer 9.9 CD4 CARTPT
32 pneumocystosis 9.9 CD4 CARTPT
33 bare lymphocyte syndrome, type ii 9.9 JAK3 CD4
34 cytomegalovirus retinitis 9.9 CD4 CARTPT
35 central nervous system hematologic cancer 9.9 CD4 CARTPT
36 cryptococcal meningitis 9.9 CD4 CARTPT
37 brachydactyly, type c 9.9 CD40 CD4
38 coccidiosis 9.9 CD4 CARTPT
39 anus disease 9.9 CD4 CARTPT
40 rectal disease 9.9 CD4 CARTPT
41 adult t-cell leukemia 9.9 JAK3 CD4
42 autoimmune disease of endocrine system 9.9 CD40 CD4
43 syphilis 9.9 CD4 CARTPT
44 b cell deficiency 9.9 CD40 CD4
45 sezary's disease 9.8 JAK3 CD4
46 mature b-cell neoplasm 9.8 CD40 CD4
47 parasitic protozoa infectious disease 9.8 CD40 CD4
48 autoimmune disease of musculoskeletal system 9.7 CD40 CD4
49 hyper ige recurrent infection syndrome 1 9.7 STAT1 CD4
50 macs syndrome 9.7 STAT1 CD4

Graphical network of the top 20 diseases related to Geotrichosis:



Diseases related to Geotrichosis

Symptoms & Phenotypes for Geotrichosis

MGI Mouse Phenotypes related to Geotrichosis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.1 CARTPT CD4 CD40 CYGB JAK3 STAT1

Drugs & Therapeutics for Geotrichosis

Search Clinical Trials , NIH Clinical Center for Geotrichosis

Cochrane evidence based reviews: geotrichosis

Genetic Tests for Geotrichosis

Anatomical Context for Geotrichosis

MalaCards organs/tissues related to Geotrichosis:

40
Lung, Skin, Tonsil

Publications for Geotrichosis

Articles related to Geotrichosis:

(show top 50) (show all 74)
# Title Authors PMID Year
1
Geotrichum capitatum septicemia: case report and review of the literature. 61
25681053 2015
2
[Pulmonary infection by Geotrichum capitatum about a case and review of the literature]. 61
25458367 2014
3
Opportunistic yeast infections: candidiasis, cryptococcosis, trichosporonosis and geotrichosis. 61
23621330 2013
4
Epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignancies. 61
23111539 2012
5
Tonsillitis in a weaner pig associated with Geotrichum candidum. 61
21217055 2011
6
Oral geotrichosis: report of 12 cases. 61
20881343 2010
7
Safety assessment of dairy microorganisms: Geotrichum candidum. 61
17869364 2008
8
A case of oral geotrichosis caused by Geotrichum capitatum in an old patient. 61
17881872 2007
9
Intra-species chromosome-length polymorphism in Geotrichum candidum revealed by pulsed field gel electrophoresis. 61
12038569 2002
10
Cutaneous geotrichosis in a dog. 61
10561789 1999
11
[Geotrichosis]. 61
10201236 1999
12
Isolation and identification of Geotrichum candidum as an etiologic agent of geotrichosis in Bulgaria. 61
10371798 1998
13
[Secondary active-evolutive cavitary pulmonary tuberculosis of the apicodorsal segment of the left upper lobe associated with bronchial tuberculosis and bronchial geotrichosis]. 61
9567625 1997
14
Geotrichosis of oral mucosa. 61
9009647 1996
15
[Intestinal geotrichosis]. 61
7837530 1994
16
[Intestinal geotrichosis]. 61
7736102 1994
17
Oral Geotrichum candidum infection associated with HIV infection. A case report. 61
1437044 1992
18
Pulmonary geotrichosis. 61
1570261 1992
19
Oral mycoses in HIV infection. 61
1549312 1992
20
A case of hitherto unreported cutaneous geotrichosis from India. 61
1452249 1992
21
Disseminated geotrichosis in two dogs. 61
2391272 1990
22
[Invasive fungal infections in hematologic malignancies--a retrospective study of 61 autopsied cases]. 61
2366325 1990
23
Cutaneous Chromomycosis with Pulmonary Geotrichosis. 61
28128150 1989
24
[General review of mycoses affecting the maxillofacial area]. 61
2678959 1989
25
[General review of maxillofacial mycoses]. 61
2577745 1989
26
Geotrichosis: who is susceptible? 61
3191781 1988
27
[Pathologic changes of the hair and nails in generalized geotrichosis]. 61
3507728 1986
28
Association of anurans with pathogenic fungi. 61
4069190 1985
29
Pulmonary geotrichosis. 61
6618526 1983
30
Mycotic infections of the alimentary tract of nonhuman primates: a review. 61
6153014 1982
31
Mycotic infections of the alimentary tract of nonhuman primates: a review. 61
6815875 1982
32
Drugs for fungal infections. 61
6893517 1980
33
Cutaneous and renal geotrichosis in a giant tortoise (Geochelone elephantopus). 61
7368044 1980
34
[Geotrichosis of the respiratory tract associated with non-specific skin changes]. 61
463007 1979
35
Gastrointestinal geotrichosis in six adult gorillas. 61
924882 1977
36
[Systemic mycoses. 4. Systemic mycoses caused by molds (aspergillosis, geotrichosis)]. 61
1010519 1976
37
Cutaneous geotrichosis in the red flamingo (Phoenicopterus ruber). 61
1265572 1976
38
Geotrichum septicemia. 61
814251 1976
39
Bronchopulmonary geotrichosis. 61
1233353 1975
40
Bronchopulmonary geotrichosis. 61
4796160 1973
41
[Geotrichosis of oral mucosa in the course of pemphigus treated with large doses of glucocorticoids]. 61
5062245 1972
42
[Cured pulmonary geotrichosis in a patient with a history of familial lung neoplasms]. 61
5160976 1971
43
Pulmonary geotrichosis and candidiasis. 61
5113696 1971
44
[A case of geotrichosis in the stump of a resected bronchus after pneumonectomy]. 61
5143439 1971
45
Bronchial geotrichosis with fungemia complicating bronchogenic carcinoma. 61
5099817 1971
46
[Geotrichosis of the urinary system and the alimentary tract in a patient with pemphigus treated protractedly with glucocorticosteroids]. 61
5482559 1970
47
Fungal superinfection: geotrichosis of the urinary tract in association with parathyroid adenoma. 61
4872500 1968
48
Disseminated geotrichosis in a dog. 61
5749201 1968
49
[A case of acute geotrichosis of the oral mucosa]. 61
5234784 1967
50
Bronchopulmonary geotrichosis with severe asthma. 61
5932737 1966

Variations for Geotrichosis

Expression for Geotrichosis

Search GEO for disease gene expression data for Geotrichosis.

Pathways for Geotrichosis

Pathways related to Geotrichosis according to GeneCards Suite gene sharing:

(show all 17)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.97 STAT1 JAK3 CD40 CD4
2
Show member pathways
12.92 STAT1 JAK3 CD40 CD4
3
Show member pathways
12.5 STAT1 JAK3 CD4
4
Show member pathways
12.48 STAT1 CD40 CD4
5
Show member pathways
12.43 STAT1 JAK3 CD40
6
Show member pathways
12.15 STAT1 JAK3 CD4
7
Show member pathways
11.85 STAT1 JAK3 CD40 CD4
8 11.77 JAK3 CD40 CD4
9
Show member pathways
11.45 STAT1 JAK3 CD4
10 11.42 STAT1 CD4
11 11.22 CD40 CD4
12 11.14 JAK3 CD4
13
Show member pathways
11.12 STAT1 JAK3
14
Show member pathways
11.03 STAT1 JAK3
15 10.97 STAT1 JAK3
16 10.8 JAK3 CD40
17 10.38 JAK3 CD40 CD4

GO Terms for Geotrichosis

Biological processes related to Geotrichosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.5 STAT1 JAK3 CD4
2 positive regulation of T cell proliferation GO:0042102 9.37 JAK3 CD4
3 interleukin-15-mediated signaling pathway GO:0035723 9.26 JAK3 CD4
4 interleukin-9-mediated signaling pathway GO:0038113 9.16 STAT1 JAK3
5 interleukin-21-mediated signaling pathway GO:0038114 8.96 STAT1 JAK3
6 enzyme linked receptor protein signaling pathway GO:0007167 8.62 JAK3 CD4

Molecular functions related to Geotrichosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 8.8 STAT1 CD40 CD4

Sources for Geotrichosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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