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MCID: GTR001
MIFTS: 30

Geotrichosis

Categories: Infectious diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Geotrichosis

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MalaCards integrated aliases for Geotrichosis:

Name: Geotrichosis 12 44 15 17 71 32

Classifications:

MalaCards categories:
Global: Infectious diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:2832
MeSH 44 D005847
SNOMED-CT 67 187105008
ICD10 32 B48.3
UMLS 71 C0017455
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Summaries for Geotrichosis

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Disease Ontology : 12 An opportunistic mycosis that has material basis in Galactomyces geotrichum, results in systemic infection in immunocompromised people.

MalaCards based summary : Geotrichosis is related to fungal infectious disease and oral candidiasis. An important gene associated with Geotrichosis is CYGB (Cytoglobin), and among its related pathways/superpathways are ERK Signaling and Akt Signaling. Affiliated tissues include skin, and related phenotype is endocrine/exocrine gland.

Wikipedia : 74 Geotrichosis is a mycosis caused by Geotrichum... more...

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Related Diseases for Geotrichosis

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Diseases related to Geotrichosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 105)
# Related Disease Score Top Affiliating Genes
1 fungal infectious disease 29.7 STAT1 CD4
2 oral candidiasis 29.5 STAT1 CD4
3 candidiasis 10.2
4 epidural abscess 10.1 CYGB CD4
5 splenic sequestration 10.1 CYGB CD4
6 aspergillosis 10.1
7 alopecia universalis congenita 10.1 JAK3 CD4
8 t-cell adult acute lymphocytic leukemia 10.1 JAK3 CD4
9 adenosine deaminase deficiency 10.0 JAK3 CD4
10 light fixation seizure syndrome 10.0 CD40LG CD40
11 sulfamethoxazole allergy 10.0 CD40LG CD40
12 pulmonary tuberculosis 10.0
13 pemphigus 10.0
14 immunodeficiency with hyper-igm, type 4 10.0 CD40LG CD40
15 congenital syphilis 10.0 CD40LG CD4
16 syphilis 10.0 CD40LG CD4
17 erythema infectiosum 10.0 CD40LG CD4
18 mature t-cell and nk-cell lymphoma 10.0 JAK3 CD4
19 brachydactyly, type c 10.0 CD40 CD4
20 inflammatory bowel disease 16 10.0 CD40LG CD40
21 secondary syphilis 10.0 CD40LG CD4
22 immunodeficiency with hyper-igm, type 5 10.0 CD40LG CD40
23 sporotrichosis 10.0 CD40LG CD4
24 congenital toxoplasmosis 10.0 CD40LG CD4
25 autoimmune disease of endocrine system 10.0 CD40 CD4
26 pneumocystosis 10.0 CD40LG CD4
27 primary thrombocytopenia 10.0 CD40LG CD4
28 cryptosporidiosis 10.0 CD40LG CD4
29 immunodeficiency with hyper-igm, type 2 10.0 CD40LG CD40
30 lymph node disease 10.0 CD40 CD4
31 anemia, autoimmune hemolytic 10.0 CD40LG CD4
32 autoimmune disease of blood 10.0 CD40LG CD4
33 plasmodium vivax malaria 9.9 CD40LG CD40
34 waldenstroem's macroglobulinemia 9.9 CD40LG CD40
35 macroglobulinemia 9.9 CD40LG CD40
36 mature b-cell neoplasm 9.9 CD40 CD4
37 meningoencephalitis 9.9 CD40LG CD4
38 immunodeficiency 35 9.9 STAT1 JAK3
39 parasitic protozoa infectious disease 9.9 CD40 CD4
40 adult t-cell leukemia 9.9 JAK3 CD4
41 temporal arteritis 9.9 CD40LG CD4
42 coccidioidomycosis 9.9 STAT1 CD4
43 potocki-shaffer syndrome 9.9 CD40 CD4
44 macs syndrome 9.9 STAT1 CD4
45 primary systemic mycosis 9.9 STAT1 CD4
46 histoplasmosis 9.9 STAT1 CD4
47 blepharitis 9.9 STAT1 CD4
48 mycobacterium tuberculosis 1 9.9
49 trichosporonosis 9.9
50 urinary tract infection 9.9

Graphical network of the top 20 diseases related to Geotrichosis:



Diseases related to Geotrichosis
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Symptoms & Phenotypes for Geotrichosis

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MGI Mouse Phenotypes related to Geotrichosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.1 CD4 CD40 CD40LG CYGB JAK3 STAT1
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Drugs & Therapeutics for Geotrichosis

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Search Clinical Trials , NIH Clinical Center for Geotrichosis

Cochrane evidence based reviews: geotrichosis

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Genetic Tests for Geotrichosis

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Anatomical Context for Geotrichosis

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MalaCards organs/tissues related to Geotrichosis:

40
Skin
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Publications for Geotrichosis

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Articles related to Geotrichosis:

(show top 50) (show all 77)
# Title Authors PMID Year
1
Geotrichosis Presenting As Funguria and Asymptomatic Urinary Tract Infection in a Patient with Renal Cyst. 61
32399350 2020
2
Cutaneous geotrichosis due to Geotrichum candidum in a burn patient. 61
32974489 2019
3
Geotrichum capitatum septicemia: case report and review of the literature. 61
25681053 2015
4
[Pulmonary infection by Geotrichum capitatum about a case and review of the literature]. 61
25458367 2014
5
Opportunistic yeast infections: candidiasis, cryptococcosis, trichosporonosis and geotrichosis. 61
23621330 2013
6
Epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignancies. 61
23111539 2012
7
Tonsillitis in a weaner pig associated with Geotrichum candidum. 61
21217055 2011
8
Oral geotrichosis: report of 12 cases. 61
20881343 2010
9
Safety assessment of dairy microorganisms: Geotrichum candidum. 61
17869364 2008
10
A case of oral geotrichosis caused by Geotrichum capitatum in an old patient. 61
17881872 2007
11
Intra-species chromosome-length polymorphism in Geotrichum candidum revealed by pulsed field gel electrophoresis. 61
12038569 2002
12
Cutaneous geotrichosis in a dog. 61
10561789 1999
13
[Geotrichosis]. 61
10201236 1999
14
Isolation and identification of Geotrichum candidum as an etiologic agent of geotrichosis in Bulgaria. 61
10371798 1998
15
[Secondary active-evolutive cavitary pulmonary tuberculosis of the apicodorsal segment of the left upper lobe associated with bronchial tuberculosis and bronchial geotrichosis]. 61
9567625 1997
16
Geotrichosis of oral mucosa. 61
9009647 1996
17
[Intestinal geotrichosis]. 61
7837530 1994
18
[Intestinal geotrichosis]. 61
7736102 1994
19
Oral Geotrichum candidum infection associated with HIV infection. A case report. 61
1437044 1992
20
Pulmonary geotrichosis. 61
1570261 1992
21
Oral mycoses in HIV infection. 61
1549312 1992
22
A case of hitherto unreported cutaneous geotrichosis from India. 61
1452249 1992
23
Disseminated geotrichosis in two dogs. 61
2391272 1990
24
[Invasive fungal infections in hematologic malignancies--a retrospective study of 61 autopsied cases]. 61
2366325 1990
25
Cutaneous Chromomycosis with Pulmonary Geotrichosis. 61
28128150 1989
26
[General review of mycoses affecting the maxillofacial area]. 61
2678959 1989
27
[General review of maxillofacial mycoses]. 61
2577745 1989
28
Geotrichosis: who is susceptible? 61
3191781 1988
29
[Pathologic changes of the hair and nails in generalized geotrichosis]. 61
3507728 1986
30
Association of anurans with pathogenic fungi. 61
4069190 1985
31
Pulmonary geotrichosis. 61
6618526 1983
32
Mycotic infections of the alimentary tract of nonhuman primates: a review. 61
6815875 1982
33
Mycotic infections of the alimentary tract of nonhuman primates: a review. 61
6153014 1982
34
Drugs for fungal infections. 61
6893517 1980
35
Cutaneous and renal geotrichosis in a giant tortoise (Geochelone elephantopus). 61
7368044 1980
36
[Geotrichosis of the respiratory tract associated with non-specific skin changes]. 61
463007 1979
37
Gastrointestinal geotrichosis in six adult gorillas. 61
924882 1977
38
[Systemic mycoses. 4. Systemic mycoses caused by molds (aspergillosis, geotrichosis)]. 61
1010519 1976
39
Cutaneous geotrichosis in the red flamingo (Phoenicopterus ruber). 61
1265572 1976
40
Geotrichum septicemia. 61
814251 1976
41
Bronchopulmonary geotrichosis. 61
1233353 1975
42
Bronchopulmonary geotrichosis. 61
4796160 1973
43
[Geotrichosis of oral mucosa in the course of pemphigus treated with large doses of glucocorticoids]. 61
5062245 1972
44
[Cured pulmonary geotrichosis in a patient with a history of familial lung neoplasms]. 61
5160976 1971
45
Pulmonary geotrichosis and candidiasis. 61
5113696 1971
46
[A case of geotrichosis in the stump of a resected bronchus after pneumonectomy]. 61
5143439 1971
47
Bronchial geotrichosis with fungemia complicating bronchogenic carcinoma. 61
5099817 1971
48
[Geotrichosis of the urinary system and the alimentary tract in a patient with pemphigus treated protractedly with glucocorticosteroids]. 61
5482559 1970
49
Fungal superinfection: geotrichosis of the urinary tract in association with parathyroid adenoma. 61
4872500 1968
50
Disseminated geotrichosis in a dog. 61
5749201 1968
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Variations for Geotrichosis

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Expression for Geotrichosis

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Search GEO for disease gene expression data for Geotrichosis.
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Pathways for Geotrichosis

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Pathways related to Geotrichosis according to GeneCards Suite gene sharing:

(show all 31)
# Super pathways Score Top Affiliating Genes
1
ERK Signaling 63
Show member pathways
 13.42 STAT1 JAK3 CD40LG CD40 CD4
2
Akt Signaling 63
Show member pathways
 12.95 STAT1 JAK3 CD40LG CD40 CD4
3
Cytokine Signaling in Immune system 65
Show member pathways
 12.83 STAT1 JAK3 CD40LG CD40 CD4
4
Measles 36
Show member pathways
 12.53 STAT1 JAK3 CD40
5
Allograft rejection 36 1
Show member pathways
 12.41 STAT1 CD40LG CD40 CD4
6
Immune response NFAT in immune response 23
Show member pathways
 12.34 CD40LG CD40 CD4
7
T cell receptor signaling pathway 36
Show member pathways
 12.31 STAT1 CD40LG CD4
8
Th17 cell differentiation 36
Show member pathways
 12.3 STAT1 JAK3 CD4
9
NF-kappaB Signaling 4
12.25 STAT1 JAK3 CD40LG
10
ICos-ICosL Pathway in T-Helper Cell 63
Show member pathways
 12.05 CD40LG CD40 CD4
11
Human T-cell leukemia virus 1 infection 36
11.99 JAK3 CD40 CD4
12
4-1BB Pathway 63
Show member pathways
 11.95 STAT1 JAK3 CD40LG CD40 CD4
13
Toxoplasmosis 36
Show member pathways
 11.91 STAT1 CD40LG CD40
14
Cell adhesion molecules 36
11.78 CD40LG CD40 CD4
15
TNF Superfamily Pathway: Human Ligand-Receptor Interactions and their Associated Functions 64
Show member pathways
 11.56 CD40LG CD40
16
Th1 Differentiation Pathway 64
Show member pathways
 11.52 STAT1 CD4
17
CXCR4-mediated signaling events 1
11.52 STAT1 CD4
18
Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway 23
Show member pathways
 11.5 CD40LG CD40
19
Commom Cytokine Receptor G Chain Siganaling Pathway 66
11.49 STAT1 JAK3
20
IgA-Producing B Cells in the Intestine 64
11.44 CD40LG CD40
21
IL4-mediated signaling events 1
11.42 JAK3 CD40LG
22
Th17 Differentiation Pathway 64
Show member pathways
 11.39 STAT1 JAK3 CD4
23
Malaria 36
11.3 CD40LG CD40
24
Th2 Differentiation Pathway 64
11.26 JAK3 CD4
25
IL-7 Signaling Pathway 1
Show member pathways
 11.22 STAT1 JAK3
26
Signaling events mediated by TCPTP 1
Show member pathways
 11.19 STAT1 JAK3
27
Inflammatory Response Pathway 1
11.05 CD40LG CD40
28
A-beta Pathways: Uptake and Degradation 64
11.03 CD40LG CD40
29
IL10 Signaling Pathway 66
10.97 JAK3 CD40
30
CD40/CD40L signaling 1
10.81 JAK3 CD40LG CD40
31
Primary immunodeficiency 36
10.5 JAK3 CD40LG CD40 CD4
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GO Terms for Geotrichosis

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Cellular components related to Geotrichosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.8 CD40LG CD40 CD4

Biological processes related to Geotrichosis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.67 STAT1 JAK3 CD4
2 tumor necrosis factor-mediated signaling pathway GO:0033209 9.58 STAT1 CD40LG CD40
3 B cell differentiation GO:0030183 9.52 JAK3 CD40LG
4 positive regulation of interleukin-12 production GO:0032735 9.51 CD40LG CD40
5 B cell proliferation GO:0042100 9.48 CD40LG CD40
6 positive regulation of endothelial cell apoptotic process GO:2000353 9.46 CD40LG CD40
7 interleukin-15-mediated signaling pathway GO:0035723 9.43 JAK3 CD4
8 interleukin-9-mediated signaling pathway GO:0038113 9.37 STAT1 JAK3
9 CD40 signaling pathway GO:0023035 9.32 CD40LG CD40
10 regulation of immunoglobulin production GO:0002637 9.26 CD40LG CD40
11 interleukin-21-mediated signaling pathway GO:0038114 9.16 STAT1 JAK3
12 enzyme linked receptor protein signaling pathway GO:0007167 8.96 JAK3 CD4
13 positive regulation of T cell proliferation GO:0042102 8.8 JAK3 CD40LG CD4

Molecular functions related to Geotrichosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.13 STAT1 CD40 CD4
2 tumor necrosis factor receptor binding GO:0005164 8.62 STAT1 CD40LG
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Sources for Geotrichosis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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