Aliases & Classifications for Germinoma

MalaCards integrated aliases for Germinoma:

Name: Germinoma 12 54 6 44 15

Classifications:



External Ids:

Disease Ontology 12 DOID:3304
MeSH 44 D018237
NCIt 50 C3753
SNOMED-CT 67 154603000
UMLS 70 C0206660

Summaries for Germinoma

Disease Ontology : 12 A germ cell cancer that lacks histologic differentiation. It usually refers to a tumor in the brain.

MalaCards based summary : Germinoma is related to central nervous system germinoma and brain germinoma. An important gene associated with Germinoma is AFP (Alpha Fetoprotein), and among its related pathways/superpathways are Peptide hormone metabolism and Glucocorticoid receptor regulatory network. The drugs Bleomycin and Cisplatin have been mentioned in the context of this disorder. Affiliated tissues include pineal, pituitary and spinal cord.

Wikipedia : 73 A germinoma is a type of germ-cell tumor, which is not differentiated upon examination. It may be benign... more...

Related Diseases for Germinoma

Diseases related to Germinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 334)
# Related Disease Score Top Affiliating Genes
1 central nervous system germinoma 32.5 POU5F1 MIR302A ALPP
2 brain germinoma 31.9 POU5F1 PAGR1 KIT ESRG AFP
3 testicular seminoma 30.9 CGB3 AFP
4 seminoma 30.7 POU5F1 PDPN KIT INHA CGB5 CGB3
5 choriocarcinoma 30.5 CGB5 CGB3 CGA ALPP
6 teratoma 30.3 POU5F1 KIT CGB5 CGB3 CGA CDH1
7 mixed germ cell tumor 30.2 KIT CGB3 CGA AFP
8 gonadal germ cell tumor 30.2 CGB5 AFP
9 extragonadal germ cell cancer 30.1 CGB5 AFP
10 gonadoblastoma 29.9 POU5F1 KIT CGB5 CGB3 ALPP
11 gonadal dysgenesis 29.8 POU5F1 KIT CGB5
12 dysgerminoma of ovary 29.8 POU5F1 MIR371A KIT ALPP AFP
13 mixed gonadal dysgenesis 29.8 KIT CYP21A2 CGB5
14 embryonal carcinoma 29.8 POU5F1 MIR302A KIT ESRG CGB5 CGB3
15 testicular cancer 29.6 CGB5 CGB3 CGA CDH1 ALPP AFP
16 mature teratoma 29.6 SALL4 POU5F1 MIR371A MIR302A KIT AFP
17 testicular germ cell cancer 29.5 MIR371A KIT ALPP AFP
18 dysgerminoma 29.5 SALL4 MIR371A KIT INHA ALPP AFP
19 myeloid sarcoma 29.3 U2AF1 PAX5 KIT
20 endodermal sinus tumor 29.1 SALL4 MIR371A MIR302A INHA CGB5 CGB3
21 germ cell cancer 28.9 SALL4 POU5F1 MIR371A MIR302A KIT CGA
22 childhood brain germinoma 11.4
23 pineal region germinoma 11.3
24 adult central nervous system germinoma 11.1
25 malignant pineal area germ cell neoplasm 11.1
26 childhood central nervous system germinoma 11.1
27 extragonadal germinoma 10.9
28 diabetes insipidus 10.7
29 germ cells tumors 10.5
30 hydrocephalus 10.5
31 hypopituitarism 10.5
32 nonseminomatous germ cell tumor 10.4 CGB5 AFP
33 chromosomal triplication 10.4 CGB3 AFP
34 polyembryoma 10.4 CGA AFP
35 pituitary hormone deficiency, combined, 2 10.4
36 pediatric testicular germ cell tumor 10.4 POU5F1 AFP
37 tuberculous epididymitis 10.4 CGB3 AFP
38 corpus luteum cyst 10.4 CGB5 AFP
39 sacrococcygeal teratoma 10.4 CGA AFP
40 triploidy 10.3 CGA AFP
41 ovarian embryonal carcinoma 10.3 POU5F1 AFP
42 colonic lymphangioma 10.3 PDPN AFP
43 precocious puberty 10.3
44 testicular fibroma 10.3 PDPN AFP
45 non-gestational ovarian choriocarcinoma 10.3 PRL AFP
46 renal pelvis adenocarcinoma 10.3 CDH1 AFP
47 anorchia 10.3 CGB5 CGA
48 gestational trophoblastic neoplasm 10.3 CGB5 CGB3 AFP
49 pineal region teratoma 10.3 KIT AFP
50 testicular leydig cell tumor 10.3 CYP21A2 CGB3

Graphical network of the top 20 diseases related to Germinoma:



Diseases related to Germinoma

Symptoms & Phenotypes for Germinoma

Drugs & Therapeutics for Germinoma

Drugs for Germinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bleomycin Approved, Investigational Phase 3 11056-06-7 5360373
2
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
3
Etoposide Approved Phase 3 33419-42-0 36462
4
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
5
Lenograstim Approved, Investigational Phase 3 135968-09-1
6
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
7
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3 1177-87-3
8
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
9
Mesna Approved, Investigational Phase 3 3375-50-6 598
10
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
11
Promethazine Approved, Investigational Phase 3 60-87-7 4927
12 Antibiotics, Antitubercular Phase 3
13 Anti-Bacterial Agents Phase 3
14 Antirheumatic Agents Phase 3
15 Immunosuppressive Agents Phase 3
16 Etoposide phosphate Phase 3
17 Adjuvants, Immunologic Phase 3
18 Tubulin Modulators Phase 3
19 Antimitotic Agents Phase 3
20 Albumin-Bound Paclitaxel Phase 3
21 Histamine H2 Antagonists Phase 3
22
Levoleucovorin Approved, Investigational Phase 2 68538-85-2 149436
23
Fluorouracil Approved Phase 2 51-21-8 3385
24
leucovorin Approved Phase 2 58-05-9 6006
25
Palbociclib Approved, Investigational Phase 2 571190-30-2 11431660 5005498 5330286
26
Metformin Approved Phase 2 657-24-9 14219 4091
27
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
28
Mechlorethamine Approved, Investigational Phase 2 51-75-2 4033
29
Ifosfamide Approved Phase 2 3778-73-2 3690
30
Folic acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
31
Lysine Approved, Nutraceutical Phase 2 56-87-1 5962
32
Alvocidib Experimental, Investigational Phase 2 146426-40-6, 131740-09-5 5287969
33 Micronutrients Phase 2
34 Antidotes Phase 2
35 Trace Elements Phase 2
36 Nutrients Phase 2
37 Vitamin B Complex Phase 2
38 Folate Phase 2
39 Protective Agents Phase 2
40 Hematinics Phase 2
41 Vitamin B9 Phase 2
42 Vitamins Phase 2
43 Calcium, Dietary Phase 2
44 Cyclin-Dependent Kinase Inhibitor Proteins Phase 2
45 Hypoglycemic Agents Phase 2
46 Podophyllotoxin Phase 2 518-28-5
47 Keratolytic Agents Phase 2
48
Isophosphamide mustard Phase 2 100427
49 Alkylating Agents Phase 2
50 Protein Kinase Inhibitors Phase 2

Interventional clinical trials:

(show all 38)
# Name Status NCT ID Phase Drugs
1 SIOP CNS GCT II: Prospective Trial for the Diagnosis and Treatment of Children, Adolescents and Young Adults With Intracranial Germ Cell Tumors Unknown status NCT01424839 Phase 4 Carboplatin, Etoposide, Ifosfamide;Cisplatin, etoposide, Ifosfamide (standard);Cisplatin, Etoposide, Ifosfamide (high dose)
2 A Phase III Study Of Reduced Therapy In The Treatment Of Children With Low And Intermediate Risk Extracranial Germ Cell Tumors Unknown status NCT00053352 Phase 3 cisplatin;etoposide
3 Radiotherapy Alone Versus Chemotherapy Followed By Response-Based Radiotherapy For Newly Diagnosed Primary CNS Germinoma Completed NCT00085098 Phase 3 carboplatin;cisplatin;cyclophosphamide;etoposide
4 A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel, Ifosfamide, and Cisplatin (TIP) With High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide Followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3 paclitaxel;ifosfamide;cisplatin;pegylated G-CSF;G-CSF;carboplatin;etoposide phosphate
5 Treatment of Intracranial Germinoma With Chemotherapy Prior to Reduced Dose and Volume of Radiotherapy Unknown status NCT02782754 Phase 2 Carboplatin;Etoposide;Cyclophosphamide;Bleomycin
6 A Non-randomized Phase 2 Study of Alvocidib (Flavopiridol) Plus Oxaliplatin With or Without 5-FU and Leucovorin for Relapsed or Refractory Germ-Cell Tumors Completed NCT00957905 Phase 2 Alvocidib Hydrochloride;Fluorouracil;Leucovorin Calcium;Oxaliplatin
7 Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer Completed NCT01037790 Phase 2 PD-0332991
8 A Prospective Evaluation of a Palliative Radio-Surgical Approach for the Treatment of Gynecologic Malignancies Completed NCT01079832 Phase 2
9 Psychosexual Intervention for Gynecologic and Breast Cancer Patients Completed NCT01764802 Phase 2
10 Treatment of Recurrent or Resistant Pediatric Malignant Germ Cell Tumors With Paclitaxel, Ifosfamide and Carboplatin Completed NCT00467051 Phase 2 Carboplatin;Ifosfamide;Paclitaxel
11 A Randomized Placebo Controlled Phase II Trial of Metformin in Conjunction With Chemotherapy Followed by Metformin Maintenance Therapy in Advanced Stage Ovarian, Fallopian Tube and Primary Peritoneal Cancer Recruiting NCT02122185 Phase 2 metformin hydrochloride;placebo;Chemotherapy
12 Phase 2 Trial of Response-Based Radiation Therapy for Patients With Localized Central Nervous System Germ Cell Tumors (CNS GCT) Active, not recruiting NCT01602666 Phase 2 Carboplatin;Etoposide;Ifosfamide
13 A Phase II Study Of Imatinib Mesylate (Gleevec, Formerly Known As STI571; IND 61,135, NSC #716051) In Patients With Refractory Seminoma Terminated NCT00042952 Phase 2 imatinib mesylate
14 Multicenter Single Arm Phase II Study of Single Agent Palifosfamide in Recurrent and Incurable Germ Cell Tumors Terminated NCT01808534 Phase 2 palifosfamide
15 A Phase I Study of SAHA and Temozolomide in Children With Relapsed or Refractory Primary Brain or Spinal Cord Tumors Completed NCT01076530 Phase 1 vorinostat;temozolomide
16 Phase I Clinical Trial of Temsirolimus and Vinorelbine in Advanced Solid Tumors. Completed NCT01155258 Phase 1 temsirolimus;vinorelbine ditartrate
17 A Phase I Study of Pazopanib as a Single Agent for Children With Relapsed or Refractory Solid Tumors Completed NCT00929903 Phase 1 pazopanib hydrochloride
18 A Phase I Study of Vorinostat and Bortezomib in Children With Refractory or Recurrent Solid Tumors, Including CNS Tumors and Lymphomas Completed NCT00994500 Phase 1 vorinostat;bortezomib
19 A Phase I Trial of the Safety and Immunogenicity of a DNA Plasmid Based Vaccine Encoding the Amino Acids 1-163 of Insulin-Like Growth Factor Binding Protein-2 (IGFBP-2) in Patients With Advanced Ovarian Cancer Completed NCT01322802 Phase 1
20 A Phase 1, Pharmacokinetic and Pharmacodynamic Study of the Combination of RO4929097 and Cediranib in Patients With Advanced Solid Tumors Completed NCT01131234 Phase 1 Gamma-Secretase Inhibitor RO4929097;Cediranib Maleate
21 A Phase I Study of Sunitinib (SU11248), an Oral Multi-Targeted Tyrosine Kinase Inhibitor, in Children With Refractory Solid Tumors Completed NCT00387920 Phase 1 sunitinib malate
22 A Phase I Study of Infusion of HER-2/Neu Specific T Cells in Patients With Advanced Stage HER-2/Neu Expressing Cancers Who Have Received a HER-2/Neu Vaccine Completed NCT00228358 Phase 1 ex vivo-expanded HER2-specific T cells;cyclophosphamide
23 Phase I Study of CCI-779 (NSC 683864) in Combination With Carboplatin and Paclitaxel in Patients With Advanced Solid Tumours Completed NCT00408655 Phase 1 paclitaxel;carboplatin;temsirolimus
24 A Multi-Center Phase Ib Study of Oxaliplatin (NSC #266046) in Combination With Fluorouracil and Leucovorin in Pediatric Patients With Advanced Solid Tumors Completed NCT00281944 Phase 1 oxaliplatin;fluorouracil;leucovorin calcium
25 A Phase I Study of UCN-01 in Combination With Irinotecan in Resistant Solid Tumor Malignancies (Part I) and in Triple Negative (ER-Negative, PgR-Negative, HER-2 Not-Amplified) Recurrent Breast Cancers (Part II) Completed NCT00031681 Phase 1 7-hydroxystaurosporine;irinotecan hydrochloride
26 A Phase I Study of a DNA Plasmid Based Vaccine Encoding the HER-2/Neu Intracellular Domain in Subjects With HER-2/Neu (HER2) Overexpressing Tumors Active, not recruiting NCT00436254 Phase 1
27 A Phase I Study of ABT-888 in Combination With Oxaliplatin and Capecitabine in Advanced Solid Tumors Terminated NCT01233505 Phase 1 veliparib;capecitabine;oxaliplatin
28 A PHASE 1/2 STUDY OF RO4929097, AN ORAL SMALL MOLECULE INHIBITOR OF GAMMA-SECRETASE, IN CHILDREN WITH RELAPSED/REFRACTORY SOLID OR CNS TUMORS, LYMPHOMA, OR T-CELL LEUKEMIA Terminated NCT01088763 Phase 1 gamma-secretase/Notch signalling pathway inhibitor RO4929097;dexamethasone
29 A Phase I Study Evaluating the Efficacy and Toxicity of Stereotactic Body Radiation for Metastatic or Recurrent Platinum-Resistant Ovarian Cancer Terminated NCT01494012 Phase 1 fludeoxyglucose F 18
30 HOPE Program: Quality of Life Enhancement and Survivorship Care Completed NCT01126346
31 A Prospective Study of Cognitive Function During Chemotherapy for Front-Line Treatment of Ovarian, Primary Peritoneal or Fallopian Tube Cancer Completed NCT01080521
32 An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors Completed NCT01445288
33 Acquisition of Human Gynecologic Specimens to be Used in Studying the Causes, Diagnosis, Prevention and Treatment of Cancer Completed NCT00897442
34 A Randomized Trial of a Family Caregiver Palliative Care Intervention Completed NCT01846520
35 Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology Recruiting NCT04648462
36 Distribution Of The Photosensitizer Motexafin Lutetium And Hypoxia In Patients With Malignancies Terminated NCT00087191 EF5;motexafin lutetium
37 Pilot Study of Mechanical Stimulation for Prevention of Hematopoietic Cell Transplant Associated Bone Density Loss Withdrawn NCT01558778
38 Integration of Palliative Care Planning in Pancreatic and Ovarian Cancers Withdrawn NCT01927393

Search NIH Clinical Center for Germinoma

Cochrane evidence based reviews: germinoma

Genetic Tests for Germinoma

Anatomical Context for Germinoma

MalaCards organs/tissues related to Germinoma:

40
Pineal, Pituitary, Spinal Cord, Brain, Testis, Medulla Oblongata, Thalamus

Publications for Germinoma

Articles related to Germinoma:

(show top 50) (show all 1522)
# Title Authors PMID Year
1
Gonadotrophin-independent precocious puberty in an eight-year-old boy due to ectopic human chorionic gonadotrophin from the central nervous system. 61 54
20400497 2010
2
Improved outcome of central nervous system germ cell tumors: implications for the role of risk-adapted intensive chemotherapy. 54 61
20191048 2010
3
Synchronous mixed germ cell tumor of the pineal gland and suprasellar region with a predominant angiomatous component: a diagnostic challenge. 61 54
19099195 2009
4
Optic nerve and chiasmal germinoma. 54 61
19300174 2009
5
Pineal region tumors--neurosurgical review. 54 61
20088167 2009
6
Management of central nervous system germinoma: proposal for a modern strategy. 54 61
19329866 2009
7
Pineal germinoma with a prominent epithelioid cell granuloma component: case report. 54 61
19106497 2008
8
Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature. 54 61
17943970 2008
9
Elevated cerebrospinal fluid levels of placental alkaline phosphatase and beta-human chorionic gonadotrophin in a case of intracranial germinoma with normal levels in blood. 61 54
18040139 2007
10
[Primitive intracranial trigeminal nerve germinoma. Case report]. 54 61
17337016 2007
11
Malignant ganglioneuroma arising from mediastinal mixed germ cell tumor. 54 61
17339149 2007
12
New immunohistochemical markers in the evaluation of central nervous system tumors: a review of 7 selected adult and pediatric brain tumors. 54 61
17284108 2007
13
OCT4: biological functions and clinical applications as a marker of germ cell neoplasia. 54 61
17117392 2007
14
[Precocious puberty caused by hCG-producing germinoma involving the bilateral basal ganglia and cerebral white matter without 1ypical radiologic findings: case report]. 54 61
16768139 2006
15
Podoplanin expression in primary central nervous system germ cell tumors: a useful histological marker for the diagnosis of germinoma. 61 54
16718353 2006
16
C-kit gene mutation: common and widely distributed in intracranial germinomas. 54 61
16572634 2006
17
C-kit expression in germinoma: an immunohistochemistry-based study. 54 61
16132509 2005
18
CNS germinoma with elevated serum human chorionic gonadotropin level: clinical characteristics and treatment outcome. 54 61
15936563 2005
19
Stereotactic radiosurgery followed by whole ventricular irradiation for primary intracranial germinoma of the pineal region. 54 61
16015498 2005
20
OCT4 immunohistochemistry is superior to placental alkaline phosphatase (PLAP) in the diagnosis of central nervous system germinoma. 54 61
15725806 2005
21
Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. 54 61
15761467 2005
22
Intracranial germ cell tumors: a single institution experience and review of the literature. 54 61
15218952 2004
23
Long-term results of radiotherapy for intracranial germinoma: a multi-institutional retrospective review of 126 patients. 61 54
14967424 2004
24
Elevated levels of human chorionic gonadotropin-beta, a marker of active neurohypophyseal germinoma, detected by immune complex transfer enzyme immunoassay. 54 61
16010454 2004
25
Germinoma with a granulomatous reaction. Problems of differential diagnosis. 61 54
12489672 2002
26
Long-term outcome of intracranial germinoma with hCG elevation in cerebrospinal fluid but not in serum. 54 61
12434171 2002
27
Composite germ cell tumor and B-cell non-Hodgkin's lymphoma arising in the sella turcica. 54 61
12395379 2002
28
CNS germinoma in a boy with simple virilizing 21-hydroxylase deficiency and precocious puberty. 61 54
11926207 2002
29
Impacts of elevated level of hCG in serum on clinical course and radiotherapy results in the histology-confirmed intracranial germinomas. 61 54
11321670 2001
30
Metastatic spinal intramedullary germinoma with elevated cerebrospinal fluid chorionic gonadotropin: a case report. 54 61
10717404 2000
31
Human chorionic gonadotrophin in CSF, not serum, predicts outcome in germinoma. 54 61
10209181 1999
32
Cerebral germinoma with syncytiotrophoblastic giant cells: feasibility of predicting prognosis using the serum hCG level. 61 54
10526079 1999
33
Extraneural metastasis of intracranial germinoma with syncytiotrophoblastic giant cells--case report. 61 54
9805904 1998
34
Occult neurohypophyseal germinomas in patients presenting with central diabetes insipidus. 54 61
17140187 1998
35
Germ cell tumours of the central nervous system: treatment consideration based on 111 cases and their long-term clinical outcomes. 54 61
9624246 1998
36
Prognosis of intracranial germinoma with syncytiotrophoblastic giant cells treated by radiation therapy. 61 54
9112445 1997
37
Aromatase expression in human germinomas with possible biological effects. 54 61
8530631 1995
38
[Successful treatment with combined chemotherapy (carboplatin, etoposide, adriamycin, bleomycin) and radiotherapy for recurrent intracranial malignant germ cell tumor: case report]. 54 61
7541899 1995
39
Primary germinoma of the spinal cord: a case report with 28-year follow-up and review of the literature. 61 54
8615089 1995
40
Tumors of the sellar region mimicking pituitary adenomas. 61 54
8299704 1993
41
[Intracranial germ cell tumors]. 54 61
1320996 1992
42
A comparative morphological and immunohistochemical study of testicular seminomas and intracranial germinomas. 61 54
2076869 1990
43
[Germinoma in a patient with emaciation and growth retardation. Case report]. 61
33749211 2021
44
Rapidly Progressing Honeycomb-Like Germinoma in the Ventricular System. 61
33792074 2021
45
Intracranial germ cells tumour: a single institution experience in Argentina. 61
33660119 2021
46
Unusual ischemic kidney injury presenting as slowly declining graft function and successful use of oral desmopressin in a kidney transplant recipient with subclinical central diabetes insipidus. 61
33560220 2021
47
ERRATUM: Comparison between Craniospinal Irradiation and Limited-Field Radiation in Patients with Non-metastatic Bifocal Germinoma. 61
33706471 2021
48
Detecting non-germinomatous germ cell tumor component by arterial spin labeling perfusion-weighted MR imaging in central nervous system germ cell tumor. 61
33460957 2021
49
Multimodality treatment for Central Nervous System Germ Cell Tumors: Disease spectrum and management strategies - A tertiary care center experience from India. 61
33508649 2021
50
Diabetes insipidus with impaired vision caused by germinoma and perioptic meningeal seeding: A case report. 61
33748249 2021

Variations for Germinoma

ClinVar genetic disease variations for Germinoma:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 PAX5 NM_016734.3(PAX5):c.1169G>A (p.Arg390His) SNV Uncertain significance 620603 rs771002648 GRCh37: 9:36840564-36840564
GRCh38: 9:36840567-36840567
2 PTCH1 NM_000264.5(PTCH1):c.1234G>A (p.Ala412Thr) SNV Uncertain significance 453775 rs370354759 GRCh37: 9:98240450-98240450
GRCh38: 9:95478168-95478168

Expression for Germinoma

Search GEO for disease gene expression data for Germinoma.

GO Terms for Germinoma

Cellular components related to Germinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.23 PRL MIR122 KIT INHA CGB5 CGB3

Biological processes related to Germinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 somatic stem cell population maintenance GO:0035019 9.13 SALL4 POU5F1 KIT
2 peptide hormone processing GO:0016486 8.8 CGB5 CGB3 CGA

Molecular functions related to Germinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.02 PRL INHA CGB5 CGB3 CGA

Sources for Germinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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