Aliases & Classifications for Gestational Diabetes

MalaCards integrated aliases for Gestational Diabetes:

Name: Gestational Diabetes 12 25 15 63 73
Gestational Diabetes Mellitus 12 76 25
Diabetes Mellitus, Gestational 25 13
Gdm 12 25
Maternal Gestational Diabetes Mellitus 12
Diabetes Mellitus Arising in Pregnancy 25
Diabetes Mellitus, Pregnancy Related 25
Diabetes, Pregnancy-Induced 25
Diabetes, Gestational 44
Diabetes Gestational 55

Classifications:



External Ids:

Disease Ontology 12 DOID:11714
ICD10 33 O24.4
MeSH 44 D016640
NCIt 50 C34942
UMLS 73 C0085207

Summaries for Gestational Diabetes

PubMed Health : 63 About gestational diabetes: Most women's blood sugar levels remain normal during pregnancy. But if blood sugar levels go above a certain value, they are considered to have gestational diabetes. This is the case in about 4 out of 100 women.It is not always clear whether a woman just has slightly higher blood sugar levels or whether she has gestational diabetes. Women’s metabolism changes over the course of pregnancy anyway: It takes longer for the cells in their body to absorb the sugar in their blood after meals. This means that elevated blood sugar levels are often a normal part of pregnancy – and they usually return to normal afterwards. Having gestational diabetes doesn’t mean that you have developed chronic diabetes.The raised blood sugar levels in gestational diabetes slightly increase the risk of certain rare birth complications. This risk can usually be lowered by changing your diet, though.The vast majority of women who develop gestational diabetes experience an otherwise normal pregnancy and go on to give birth to a healthy baby.

MalaCards based summary : Gestational Diabetes, also known as gestational diabetes mellitus, is related to maturity-onset diabetes of the young, type 2 and fetal macrosomia, and has symptoms including hyperemesis gravidarum, pelvic pain and morning sickness. An important gene associated with Gestational Diabetes is INS (Insulin), and among its related pathways/superpathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Regulation of lipid metabolism Insulin signaling-generic cascades. The drugs Resveratrol and Insulin Aspart have been mentioned in the context of this disorder. Affiliated tissues include testes, ovary and placenta, and related phenotypes are homeostasis/metabolism and adipose tissue

Genetics Home Reference : 25 Gestational diabetes is a disorder characterized by abnormally high blood sugar levels during pregnancy. Affected women do not have diabetes before they are pregnant, and most of these women go back to being nondiabetic soon after the baby is born. The disease has a 30 to 70 percent chance of recurring in subsequent pregnancies. Additionally, about half of women with gestational diabetes develop another form of diabetes, known as type 2 diabetes, within a few years after their pregnancy.

Wikipedia : 76 Gestational diabetes is a condition in which a woman without diabetes develops high blood sugar levels... more...

Related Diseases for Gestational Diabetes

Diseases related to Gestational Diabetes via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 129)
# Related Disease Score Top Affiliating Genes
1 maturity-onset diabetes of the young, type 2 32.7 GCK INS
2 fetal macrosomia 31.5 INS INSR LEP
3 monogenic diabetes 30.8 GCK INS KCNJ11
4 apnea, obstructive sleep 30.7 ADIPOQ INS LEP
5 sleep apnea 30.6 ADIPOQ INS LEP
6 severe pre-eclampsia 30.4 ADIPOQ LEP RBP4
7 polycystic ovary syndrome 30.4 INS INSR IRS1 LEP SHBG
8 hypoglycemia 30.3 GCK INS INSR KCNJ11
9 hyperinsulinemic hypoglycemia 30.1 GCK INS INSR KCNJ11
10 maturity-onset diabetes of the young 30.0 GCK INS IRS1 KCNJ11
11 acanthosis nigricans 29.9 ADIPOQ INS INSR LEP SHBG
12 hyperglycemia 29.7 ADIPOQ GCK INS INSR IRS1 KCNJ11
13 hyperinsulinism 29.6 GCK INS INSR KCNJ11 LEP SHBG
14 glucose intolerance 27.5 ADIPOQ ADRB3 GCK INS INSR IRS1
15 overnutrition 27.5 ADIPOQ ADRB3 INS IRS1 LEP NAMPT
16 diabetes mellitus 26.5 ADIPOQ ADRB3 GCK HKDC1 INS INSR
17 diabetes mellitus, noninsulin-dependent 23.2 ADIPOQ ADIPOR1 ADRB3 GCK INS INSR
18 gestational diabetes insipidus 12.2
19 insulin autoimmune syndrome 10.9 INS INSR
20 congenital anomalies of kidney and urinary tract 2 10.9
21 diabetes mellitus, transient neonatal, 3 10.9
22 munchausen by proxy 10.8 GCK KCNJ11
23 nonalcoholic steatohepatitis 10.8 ADIPOQ INS LEP
24 acute insulin response 10.8 INS KCNJ11 TCF7L2
25 factitious disorder 10.8 GCK INS KCNJ11
26 alstrom syndrome 10.7 INS KCNJ11 LEP
27 pancreas disease 10.7 INS KCNJ11 LEP
28 pancreatic agenesis 10.7 GCK INS KCNJ11
29 inherited metabolic disorder 10.7 ADIPOQ INS LEP
30 acquired generalized lipodystrophy 10.7 ADIPOQ LEP RETN
31 obesity-hypoventilation syndrome 10.7 ADIPOQ LEP RETN
32 diabetes mellitus, permanent neonatal 10.6 GCK INS KCNJ11
33 coronary artery aneurysm 10.6 ADIPOQ LEP RETN
34 coronary heart disease 1 10.6 ADIPOQ INS RETN
35 pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities 10.6 INS INSR
36 anovulation 10.6 INS LEP SHBG
37 arteries, anomalies of 10.6 ADIPOQ INS LEP
38 lipodystrophy, familial partial, type 2 10.6 INS LEP
39 neonatal diabetes mellitus 10.6 GCK INS KCNJ11
40 prediabetes syndrome 10.6 ADIPOQ INS LEP TCF7L2
41 uremia 10.5 INS LEP RETN
42 hyperandrogenism 10.5 INS INSR SHBG
43 hyperthyroidism 10.4 INS LEP SHBG
44 idiopathic recurrent pericarditis 10.4 ADIPOQ LEP NAMPT RETN
45 abdominal obesity-metabolic syndrome quantitative trait locus 2 10.4 INS LEP SLC2A4
46 prader-willi syndrome 10.4 ADIPOQ INS LEP RETN
47 placenta disease 10.3
48 lipid metabolism disorder 10.3 ADIPOQ INS LEP RBP4 RETN
49 3-hydroxyacyl-coa dehydrogenase deficiency 10.2 ADIPOQ GCK INS LEP RETN
50 endotheliitis 10.2

Graphical network of the top 20 diseases related to Gestational Diabetes:



Diseases related to Gestational Diabetes

Symptoms & Phenotypes for Gestational Diabetes

UMLS symptoms related to Gestational Diabetes:


hyperemesis gravidarum, pelvic pain, morning sickness

MGI Mouse Phenotypes related to Gestational Diabetes:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.38 RBP4 IRS1 LEP IRS2 NAMPT PAPPA
2 adipose tissue MP:0005375 10.32 IRS1 LEP IRS2 KCNJ11 INSR ADRB3
3 growth/size/body region MP:0005378 10.31 KCNJ11 IRS1 LEP NAMPT IRS2 PAPPA
4 endocrine/exocrine gland MP:0005379 10.3 PTPRN RBP4 IRS1 LEP IRS2 NAMPT
5 cardiovascular system MP:0005385 10.26 KCNJ11 IRS1 LEP NAMPT IRS2 PAPPA
6 behavior/neurological MP:0005386 10.19 KCNJ11 LEP IRS2 ADIPOR1 ADRB3 INSR
7 immune system MP:0005387 10.11 PTPRN IRS1 LEP NAMPT IRS2 INSR
8 liver/biliary system MP:0005370 10.1 IRS1 LEP IRS2 INSR GCK ADIPOQ
9 mortality/aging MP:0010768 10.03 KCNJ11 IRS1 LEP NAMPT IRS2 INSR
10 muscle MP:0005369 9.9 KCNJ11 IRS1 LEP IRS2 INSR ADIPOQ
11 renal/urinary system MP:0005367 9.5 LEP IRS2 INSR GCK ADIPOQ INS
12 skeleton MP:0005390 9.28 IRS1 LEP PAPPA ADIPOR1 ADIPOQ INS

Drugs & Therapeutics for Gestational Diabetes

PubMedHealth treatment related to Gestational Diabetes: 63

A change in diet is usually enough to make the levels return to normal. Women with gestational diabetes can get advice from their doctor. Special dietary counseling can be helpful too. Another way to lower your blood sugar levels is by getting more exercise. In some pregnant women the blood sugar levels stay high for so long that they have to inject insulin or, in rare cases, take medicine for diabetes.The doctor will offer to measure the woman’s blood sugar levels again after the baby is born. If her blood sugar levels have returned to normal, no more treatment is needed.

Drugs for Gestational Diabetes (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 256)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Resveratrol Approved, Experimental, Investigational Phase 4 501-36-0 445154
2
Insulin Aspart Approved Phase 4,Phase 3,Phase 2,Not Applicable 116094-23-6 16132418
3
Zinc Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 7440-66-6 23994
4
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 657-24-9 14219 4091
5
Glyburide Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 10238-21-8 3488
6
Cyproterone Acetate Approved, Investigational Phase 4 427-51-0
7
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
8 Estradiol valerate Approved, Investigational, Vet_approved Phase 4 979-32-8
9
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
10
Polyestradiol phosphate Approved Phase 4 28014-46-2
11
Insulin Lispro Approved Phase 4,Phase 2,Not Applicable 133107-64-9
12
Liraglutide Approved Phase 4,Phase 3 204656-20-2 44147092
13
Exenatide Approved, Investigational Phase 4,Not Applicable 141758-74-9 15991534
14
Silicon Approved, Investigational Phase 4 7440-21-3 4082203
15
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3,Not Applicable 59-30-3 6037
16
leucovorin Approved, Nutraceutical Phase 4,Phase 2,Phase 3,Not Applicable 58-05-9 143 6006
17
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 50-14-6 5280793
18
Vitamin D Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 1406-16-2
19
Vitamin D3 Approved, Nutraceutical Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 67-97-0 6221 5280795
20
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067
21 Analgesics Phase 4
22 Analgesics, Non-Narcotic Phase 4
23 Anti-Inflammatory Agents Phase 4,Phase 2
24 Anti-Inflammatory Agents, Non-Steroidal Phase 4
25 Antineoplastic Agents, Phytogenic Phase 4
26 Antioxidants Phase 4,Phase 2,Phase 3
27 Antirheumatic Agents Phase 4,Phase 2
28 Hypoglycemic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
29 insulin Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
30 Insulin, Globin Zinc Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
31 Peripheral Nervous System Agents Phase 4,Phase 2,Not Applicable
32 Platelet Aggregation Inhibitors Phase 4
33 Protective Agents Phase 4,Phase 2,Not Applicable
34 Pharmaceutical Solutions Phase 4,Not Applicable
35 Hematinics Phase 4,Phase 2,Phase 3,Not Applicable
36 Micronutrients Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
37 Trace Elements Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
38 Vitamin B Complex Phase 4,Phase 2,Phase 3,Not Applicable
39 Vitamins Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
40 Androgen Antagonists Phase 4
41 Androgens Phase 4,Phase 2
42 Contraceptive Agents Phase 4,Not Applicable
43 Contraceptive Agents, Male Phase 4
44
Cyproterone Phase 4 2098-66-0 5284537
45 Cyproterone acetate, ethinyl estradiol drug combination Phase 4
46 Estradiol 17 beta-cypionate Phase 4
47 Estradiol 3-benzoate Phase 4
48 Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable
49 Hormones Phase 4,Phase 3,Phase 2,Not Applicable
50 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Not Applicable

Interventional clinical trials:

(show top 50) (show all 539)
# Name Status NCT ID Phase Drugs
1 Can Resveratrol Improve Insulin Sensitivity and Preserve Beta Cell Function Following Gestational Diabetes? Unknown status NCT01997762 Phase 4
2 Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial Unknown status NCT02590016 Phase 4 Insulin, Aspart
3 Metformin and Gestational Diabetes in High-risk Patients: a RCTs Unknown status NCT00883259 Phase 4 Metformin
4 Prevention of Diabetes Mellitus Development in Women Who Had Already Experienced A Gestational Diabetes Unknown status NCT00265746 Phase 4 Metformin
5 Oral Antidiabetic Agents in Pregnancy Unknown status NCT02091336 Phase 4 Metformin;Glyburide
6 Efficacy of Myo-inositol in Preventing Gestational Diabetes in High-risk Pregnant Women Unknown status NCT01511835 Phase 4 Folic Acid
7 Effectiveness of Metformin in Recurrent Miscarriage in a Woman With Hyperinsulinaemia Unknown status NCT01718340 Phase 4 Metformin
8 the Effect of Diane-35 Pretreatment on In-vitro Fertilization Outcome for Patients With Polycystic Ovary Syndrome Unknown status NCT01752270 Phase 4 Diane-35 pretreatment;Diane-35 pretreatment
9 Therapeutic Monitoring of Metformin in Women With Polycystic Ovary Syndrome Unknown status NCT01366391 Phase 4 Metformin
10 A Trial to Study the Effect of Long Term Vitamin D Supplementation on Insulin Sensitivity Unknown status NCT01052181 Phase 4 Cholecalciferol;placebo
11 Antioxidants in Gestational Diabetes Completed NCT02355197 Phase 4 L-ascorbic acid
12 Metformin Versus Insulin in Gestational Diabetes Completed NCT01240785 Phase 4 metformin;insulin
13 Medical Nutrition Therapy Plus Transgestational Metformin For Preventing Gestational Diabetes In High Risk Mexican Women Completed NCT01675310 Phase 4 medical nutrition therapy + metformin
14 Treatment of Mild Gestational Diabetes With Glyburide Versus Placebo Completed NCT00744965 Phase 4 Glyburide;Placebo
15 Humalog® Mix50/50(tm) as a Treatment for Gestational Diabetes Completed NCT01613807 Phase 4 Insulin LISPRO;Insulin, Long-Acting and Insulin LISPRO
16 A Comparison Between Two Oral Hypoglycemics - Metformin and Glybenclamide for the Treatment of Gestational Diabetes Mellitus Completed NCT01563120 Phase 4 metformin;glybenclamide
17 Metformin Postpartum for GDM RCT for Reduced Weight Retention Completed NCT01280409 Phase 4 Metformin;Placebo
18 Sitagliptin + Metformin Compared to Metformin Monotherapy and Placebo in Women With a Recent GDM Completed NCT01856907 Phase 4 Sitagliptin-Metformin;Metformin;Placebo pill
19 Resistance Exercise Training During Pregnancy: a Randomized Controlled Trial Completed NCT00813657 Phase 4
20 Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients Completed NCT02466204 Phase 4 corifollitropin alfa;Follitropin Beta
21 Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Boostrix™ Vaccine in Pregnant Women Completed NCT02377349 Phase 4 Saline placebo
22 Preventing Recurrent Gestational Diabetes With Metformin Recruiting NCT02394158 Phase 4 Metformin;placebo
23 Metabolic Analysis for Treatment Choice in Gestational Diabetes Mellitus Recruiting NCT03029702 Phase 4 Insulin;Glyburide;Metformin
24 Effect of Probiotics (Vivomixx®) on Weight, Microbiota and Glucose Tolerance in Obese Pregnant Women and Their Newborn Recruiting NCT02508844 Phase 4
25 ZIMBA: Clinical Trial in Paediatric Obesity Recruiting NCT03283813 Phase 4 Placebos;Myoinositol
26 Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology Recruiting NCT03177122 Phase 4 Myo-inositol
27 The Impact of Liraglutide on Glucose Tolerance and the Risk of Type 2 Diabetes in Women With Previous Pregnancy-induced Diabetes Active, not recruiting NCT01795248 Phase 4 Liraglutide;Placebo
28 The Impact of Vitamin D Supplementation on Glucose Metabolism in Chinese Women With Former Gestational Diabetes Mellitus Enrolling by invitation NCT03138616 Phase 4 vitamin D
29 Threshold for Initiation of Medical Treatment for Women With Gestational Diabetes Not yet recruiting NCT03527537 Phase 4 Insulin;Glyburide;Metformin
30 Probiotics in Newly Recognized Type 1 Diabetes Not yet recruiting NCT03032354 Phase 4 Lactobacillus rhamnosus GG and Bifidobacterium lactis BB12
31 Metformin for Preeclampsia Prevention in Pregnant Women With Type 1 Diabetes Mellitus Not yet recruiting NCT03570632 Phase 4 Metformin
32 The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation Not yet recruiting NCT03468907 Phase 4 Telbivudine 600mg;Tenofovir disoproxil fumarate 300mg
33 Glyburide Compared to Insulin in the Management of White's Classification A2 Gestational Diabetes Withdrawn NCT00160485 Phase 4 Glyburide;Insulin
34 Pilot Study of Exenatide Pharmacokinetics and Pharmacodynamics in Gestational Diabetes Withdrawn NCT00572689 Phase 4 Exenatide
35 Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide Withdrawn NCT01947699 Phase 4 Glyburide
36 Failure Rate of GLyburide And Metformin Among Gestational Diabetics Withdrawn NCT03078725 Phase 4 Glyburide;Metformin
37 Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus Unknown status NCT02275845 Phase 3 Metformin
38 Metformin Treatment in Gestational Diabetes and Noninsulin Dependent Diabetes in Pregnancy in a Developing Country Unknown status NCT01855763 Phase 2, Phase 3 Metformin;Insulin
39 Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome Unknown status NCT02802215 Phase 2, Phase 3 metformin;placebo (folic acid )
40 Metformin for the Treatment of Diabetes in Pregnancy Unknown status NCT00414245 Phase 3 metformin
41 Modulation of the Intestinal Flora With the Probiotic VIVOMIXX™ in Pregnant Women at Risk of Metabolic Complications Unknown status NCT02768818 Phase 3
42 Probiotics (Lactobacillus Rhamnosus) in Reducing Glucose Intolerance During and After Pregnancy Unknown status NCT01436448 Phase 3 Probiotics Lactobacillus Rhamnosus
43 A Randomized Clinical Trial of Oral Magnesium Supplementation in Pregnancy Unknown status NCT02032186 Phase 3 Magnesium citrate
44 A Randomized Trial of Docosahexaenoic Acid Supplementation During Pregnancy to Prevent Deep Placentation Disorders Unknown status NCT02336243 Phase 3
45 Metformin Versus Insulin in the Treatment of Gestational Diabetes Mellitus Completed NCT01087866 Phase 2, Phase 3 Metformin;Insulin
46 Gestational Diabetes: Insulin or Oral Hypoglycemic Agents? Completed NCT01215331 Phase 3 Insulin;Metformin, glyburide and insulin
47 Comparison of Metformin and Insulin for Management of Gestational Diabetes Mellitus Completed NCT03320694 Phase 3 Metformin;Insulin
48 Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes Completed NCT01731431 Phase 3 Glyburide
49 A Feasibility Study Looking at the Use of Glibenclamide and metfoRmin Versus stAndard Care in gEstational diabeteS Completed NCT02080377 Phase 3 Glibenclamide;Insulin
50 Safety and Efficacy of Insulin Aspart vs. Regular Human Insulin in Gestational Diabetes Completed NCT00065130 Phase 3 human insulin;insulin NPH;insulin aspart

Search NIH Clinical Center for Gestational Diabetes

Cochrane evidence based reviews: diabetes, gestational

Genetic Tests for Gestational Diabetes

Anatomical Context for Gestational Diabetes

MalaCards organs/tissues related to Gestational Diabetes:

41
Testes, Ovary, Placenta, Breast, Thyroid, Liver, Endothelial

Publications for Gestational Diabetes

Articles related to Gestational Diabetes:

(show top 50) (show all 1368)
# Title Authors Year
1
Maternal lipids, BMI and IL-17/IL-35 imbalance in concurrent gestational diabetes mellitus and preeclampsia. ( 29977366 )
2018
2
Hemoglobin levels during the first trimester of pregnancy are associated with the risk of gestational diabetes mellitus, pre-eclampsia and preterm birth in Chinese women: a retrospective study. ( 29940874 )
2018
3
Postpartum risk of diabetes and predictive factors for glucose intolerance in East Asian women with gestational diabetes. ( 29596944 )
2018
4
Recent gestational diabetes was associated with mothers stopping predominant breastfeeding earlier in a multi-ethnic population. ( 29432660 )
2018
5
Barriers to a healthy lifestyle for three- to four-year-old children of Australian-born and overseas-born mothers with post-gestational diabetes: An Australian qualitative study. ( 29444583 )
2018
6
Type 2 Diabetes after Gestational diabetes: Can the progression be prevented? ( 29430798 )
2018
7
History of mood or anxiety disorders and risk of gestational diabetes mellitus in a population-based cohort. ( 29120506 )
2018
8
Maternal gestational diabetes mellitus: is it associated with long-term pediatric ophthalmic morbidity of the offspring? ( 29429374 )
2018
9
A Cautionary Response to SMFM Statement: Pharmacological Treatment of Gestational Diabetes. ( 29959933 )
2018
10
Hyperlipidemia during gestational diabetes and its relation with maternal and offspring complications. ( 29974782 )
2018
11
Inflammatory Markers in Older Women with a History of Gestational Diabetes and the Effects of Weight Loss. ( 29951553 )
2018
12
Level of maternal triglycerides is a predictor of fetal macrosomia in non-obese pregnant women with gestational diabetes mellitus. ( 29398554 )
2018
13
Association between chemerin rs17173608 and rs4721 gene polymorphisms and gestational diabetes mellitus in Iranian pregnant women. ( 29360607 )
2018
14
Screening for gestational diabetes in low-risk women: effect of maternal age. ( 29425107 )
2018
15
Exploration of predictive metabolic factors for gestational diabetes mellitus in Japanese women using metabolomic analysis. ( 29956893 )
2018
16
Analysis of the correlation of gestational diabetes mellitus and peripheral ferritin with iron levels in early pregnancy. ( 29442476 )
2018
17
Metformin or insulin: logical treatment in women with gestational diabetes in the Middle East, our experience. ( 29970197 )
2018
18
Calcium Channel Blockers as Drug Repurposing Candidates for Gestational Diabetes: Mining large scale genomic and electronic health records data to repurpose medications. ( 29448118 )
2018
19
Circulating B-type natriuretic peptide in women with and without recent gestational diabetes: The impact of current glucose intolerance. ( 29112786 )
2018
20
The Impact of Health Locus of Control and Anxiety on Self-Monitored Blood Glucose Concentration in Women with Gestational Diabetes Mellitus. ( 28829663 )
2018
21
The Impact of Prepregnancy Body Mass Index and Gestational Weight Gain on Perinatal Outcomes for Women With Gestational Diabetes Mellitus. ( 29962105 )
2018
22
A nested case-control study of the association between exposure to polybrominated diphenyl ethers and the risk of gestational diabetes mellitus. ( 29980046 )
2018
23
Cadmium Body Burden and Gestational Diabetes Mellitus: A Prospective Study. ( 29425094 )
2018
24
Evidence for the utility of antenatal HbA1c to predict early postpartum diabetes after gestational diabetes in South Africa. ( 29969724 )
2018
25
Effects of Vitamin D Deficiency on Incidence Risk of Gestational Diabetes Mellitus: A Systematic Review and Meta-analysis. ( 29449829 )
2018
26
Daily walking is effective for the management of pregnant women with gestational diabetes mellitus. ( 29974564 )
2018
27
Increased risk of ischemic heart disease, hypertension, and type 2 diabetes in women with previous gestational diabetes mellitus, a target group in general practice for preventive interventions: A population-based cohort study. ( 29337985 )
2018
28
A retrospective study of supplemental iron intake in singleton pregnancy women with risk of developing gestational diabetes mellitus. ( 29952938 )
2018
29
The impact of a daily smartphone-based feedback system among women with gestational diabetes on compliance, glycemic control, satisfaction, and pregnancy outcome: a randomized controlled trial. ( 29425836 )
2018
30
Combination of first trimester serum afamin levels and three-dimensional placental bed vascularization as a possible screening method to detect women at-risk for adverse pregnancy complications like pre-eclampsia and gestational diabetes mellitus in low-risk pregnancies. ( 29405972 )
2018
31
Therapies for gestational diabetes and their implications for maternal and offspring health: Evidence from human and animal studies. ( 29421161 )
2018
32
Factors predicting early postpartum glucose intolerance in Japanese women with gestational diabetes mellitus: decision-curve analysis. ( 29706019 )
2018
33
A case-control study and meta-analysis confirm glucokinase regulatory gene rs780094 is a risk factor for gestational diabetes mellitus. ( 29410004 )
2018
34
Temporal changes in characteristics and outcomes among pregnant women with pre-gestational diabetes. ( 29978470 )
2018
35
Effectiveness of a diabetes prevention program for rural women with prior gestational diabetes mellitus: study protocol of a multi-site randomized clinical trial. ( 29954367 )
2018
36
Correlation between plasma ferritin level and gestational diabetes mellitus and its impact on fetal macrosomia. ( 29542249 )
2018
37
Is Chemerin associated with gestational diabetes mellitus? An evidence-based clinical research from Chinese women. ( 29430984 )
2018
38
Urinary Inorganic Arsenic Concentration and Gestational Diabetes Mellitus in Pregnant Women from Arica, Chile. ( 29976896 )
2018
39
Evaluation of the diabetes in pregnancy study group of India criteria and Carpenter-Coustan criteria in the diagnosis of gestational diabetes mellitus. ( 29971182 )
2018
40
Fatty acid-binding protein 4 predicts gestational hypertension and preeclampsia in women with gestational diabetes mellitus. ( 29394285 )
2018
41
Incidence and risk factors for gestational diabetes mellitus in twin versus singleton pregnancies. ( 29971559 )
2018
42
Effect of gestational diabetes and hypertensive disorders of pregnancy on postpartum cardiometabolic risk. ( 29444890 )
2018
43
HBsAg positivity during pregnancy and risk of gestational diabetes mellitus: a systematic review and meta-analysis. ( 29968379 )
2018
44
Metformin in women at high risk of gestational diabetes mellitus. ( 29422358 )
2018
45
Pregnancy Outcomes in Women with an Early Diagnosis of Gestational Diabetes Mellitus. ( 29427694 )
2018
46
Is There a Relationship Between Gestational Diabetes and Perinatal Depression? ( 29958203 )
2018
47
Functional Defects of Regulatory T Cell Through Interleukin 10 Mediated Mechanism in the Induction of Gestational Diabetes Mellitus. ( 29298097 )
2018
48
Higher Concentrations of BCAAs and 3-HIB Are Associated with Insulin Resistance in the Transition from Gestational Diabetes to Type 2 Diabetes. ( 29967793 )
2018
49
Managing Gestational Diabetes Postpartum. ( 29958206 )
2018
50
The effects of synbiotic supplementation on insulin resistance/sensitivity, lipid profile and total antioxidant capacity in women with gestational diabetes mellitus: a randomized double blind placebo controlled clinical trial. ( 29432772 )
2018

Variations for Gestational Diabetes

Expression for Gestational Diabetes

Search GEO for disease gene expression data for Gestational Diabetes.

Pathways for Gestational Diabetes

Pathways related to Gestational Diabetes according to GeneCards Suite gene sharing:

(show all 30)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.49 ADIPOQ ADIPOR1 ADRB3 INS INSR IRS1
2
Show member pathways
12.86 GCK HKDC1 INS INSR IRS1 IRS2
3
Show member pathways
12.73 ADIPOQ INS INSR IRS1 IRS2 LEP
4
Show member pathways
12.72 INS INSR IRS1 IRS2 SLC2A4
5
Show member pathways
12.65 ADRB3 INS INSR IRS1 IRS2
6 12.51 ADIPOQ INS INSR IRS1 IRS2 NAMPT
7
Show member pathways
12.46 INS INSR IRS1 IRS2 SLC2A4
8
Show member pathways
12.43 GCK INS IRS1 IRS2 LEP
9
Show member pathways
12.34 ADIPOQ ADIPOR1 INS INSR IRS1 IRS2
10
Show member pathways
12.29 ADIPOQ ADIPOR1 INS KCNJ11
11
Show member pathways
12.21 INS INSR IRS1 IRS2 LEP SLC2A4
12
Show member pathways
12.11 ADIPOQ ADIPOR1 INS INSR IRS1 IRS2
13
Show member pathways
12.06 INS INSR IRS1 IRS2 SLC2A4
14
Show member pathways
11.95 INS INSR IRS1 IRS2 SLC2A4
15 11.88 INSR IRS1 TCF7L2
16 11.88 ADIPOQ INS IRS1 IRS2 LEP NAMPT
17 11.81 HKDC1 INS INSR
18 11.68 ADIPOQ ADIPOR1 IRS1 IRS2 LEP SLC2A4
19 11.61 INS INSR IRS1
20 11.56 ADRB3 INS INSR IRS1 IRS2
21 11.54 INS INSR IRS1 LEP
22 11.52 IRS1 IRS2 KCNJ11 LEP SLC2A4
23 11.42 GCK INS KCNJ11
24 11.41 INS INSR IRS1
25 11.34 INS INSR IRS1
26
Show member pathways
11.26 ADIPOQ GCK HKDC1 INS INSR IRS1
27 11.21 INS INSR SLC2A4
28
Show member pathways
10.94 INSR IRS1 SLC2A4
29 10.85 INS SLC2A4
30 10.78 ADIPOQ INSR IRS1 IRS2 LEP SLC2A4

GO Terms for Gestational Diabetes

Cellular components related to Gestational Diabetes according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 insulin receptor complex GO:0005899 8.62 INSR IRS1

Biological processes related to Gestational Diabetes according to GeneCards Suite gene sharing:

(show all 41)
# Name GO ID Score Top Affiliating Genes
1 carbohydrate metabolic process GO:0005975 9.97 ADRB3 GCK HKDC1 INS INSR SLC2A4
2 insulin receptor signaling pathway GO:0008286 9.88 INS INSR IRS1 IRS2 NAMPT
3 positive regulation of protein kinase B signaling GO:0051897 9.88 INS INSR IRS1 IRS2 LEP TCF7L2
4 positive regulation of MAPK cascade GO:0043410 9.87 ADRB3 INS INSR LEP
5 response to ethanol GO:0045471 9.85 ADIPOQ LEP RBP4 SLC2A4
6 response to glucose GO:0009749 9.85 ADIPOQ INS IRS2 PTPRN TCF7L2
7 female pregnancy GO:0007565 9.84 LEP NAMPT PAPPA
8 regulation of lipid metabolic process GO:0019216 9.84 ADIPOR1 IRS1 IRS2
9 circadian rhythm GO:0007623 9.83 ADIPOQ LEP NAMPT
10 response to insulin GO:0032868 9.83 INS IRS1 LEP PTPRN RETN
11 positive regulation of insulin secretion GO:0032024 9.81 GCK IRS2 RBP4 TCF7L2
12 regulation of insulin secretion GO:0050796 9.8 GCK KCNJ11 LEP
13 cellular response to insulin stimulus GO:0032869 9.8 ADIPOQ GCK INSR IRS1 IRS2 SLC2A4
14 response to nutrient levels GO:0031667 9.79 ADIPOQ INS LEP
15 cellular response to glucose stimulus GO:0071333 9.79 IRS2 KCNJ11 SLC29A1
16 brown fat cell differentiation GO:0050873 9.71 ADIPOQ ADRB3 SLC2A4
17 negative regulation of gluconeogenesis GO:0045721 9.7 ADIPOQ GCK INS
18 positive regulation of glycolytic process GO:0045821 9.68 INS INSR
19 positive regulation of glucose import in response to insulin stimulus GO:2001275 9.68 INS IRS1
20 positive regulation of cellular protein metabolic process GO:0032270 9.68 ADIPOQ INS
21 energy reserve metabolic process GO:0006112 9.68 ADRB3 LEP
22 cellular glucose homeostasis GO:0001678 9.67 GCK HKDC1
23 fatty acid oxidation GO:0019395 9.67 ADIPOQ ADIPOR1
24 positive regulation of insulin receptor signaling pathway GO:0046628 9.67 ADIPOR1 INS IRS1 LEP
25 glucose 6-phosphate metabolic process GO:0051156 9.65 GCK HKDC1
26 cellular response to leptin stimulus GO:0044320 9.65 GCK LEP
27 leptin-mediated signaling pathway GO:0033210 9.65 ADIPOR1 LEP
28 positive regulation of glucose import GO:0046326 9.65 ADIPOQ INS INSR IRS1 IRS2
29 regulation of fatty acid biosynthetic process GO:0042304 9.64 ADIPOQ ADIPOR1
30 positive regulation of fatty acid beta-oxidation GO:0032000 9.64 IRS1 IRS2
31 positive regulation of glucose metabolic process GO:0010907 9.63 IRS1 IRS2
32 glucose metabolic process GO:0006006 9.63 ADIPOQ GCK INS IRS2 KCNJ11 LEP
33 negative regulation of feeding behavior GO:2000252 9.61 INS RETN
34 positive regulation of respiratory burst GO:0060267 9.6 INS INSR
35 neuron projection maintenance GO:1990535 9.59 INS INSR
36 adiponectin-activated signaling pathway GO:0033211 9.58 ADIPOQ ADIPOR1
37 positive regulation of developmental growth GO:0048639 9.58 INSR LEP
38 positive regulation of glycogen biosynthetic process GO:0045725 9.35 GCK INS INSR IRS1 IRS2
39 glucose homeostasis GO:0042593 9.32 ADIPOQ ADIPOR1 GCK INS INSR IRS1
40 regulation of signaling receptor activity GO:0010469 10.03 ADIPOQ INS LEP NAMPT RETN
41 positive regulation of cell proliferation GO:0008284 10.03 INS INSR IRS1 IRS2 LEP NAMPT

Molecular functions related to Gestational Diabetes according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.56 ADIPOQ INS LEP RETN
2 glucose binding GO:0005536 9.46 GCK HKDC1
3 glucokinase activity GO:0004340 9.43 GCK HKDC1
4 fructokinase activity GO:0008865 9.4 GCK HKDC1
5 mannokinase activity GO:0019158 9.37 GCK HKDC1
6 insulin receptor binding GO:0005158 9.33 INS IRS1 IRS2
7 hexokinase activity GO:0004396 9.32 GCK HKDC1
8 phosphatidylinositol 3-kinase binding GO:0043548 9.13 INSR IRS1 IRS2
9 insulin-like growth factor receptor binding GO:0005159 8.8 INS INSR IRS1

Sources for Gestational Diabetes

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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