MCID: GST035
MIFTS: 23

Gestational Ovarian Choriocarcinoma

Categories: Cancer diseases, Endocrine diseases, Fetal diseases, Reproductive diseases

Aliases & Classifications for Gestational Ovarian Choriocarcinoma

MalaCards integrated aliases for Gestational Ovarian Choriocarcinoma:

Name: Gestational Ovarian Choriocarcinoma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:7591
NCIt 49 C40442
UMLS 71 C1517538

Summaries for Gestational Ovarian Choriocarcinoma

Disease Ontology : 12 A choriocarcinoma of the ovary that develops in the presence of a preceding gestational event.

MalaCards based summary : Gestational Ovarian Choriocarcinoma is related to non-gestational ovarian choriocarcinoma and choriocarcinoma. An important gene associated with Gestational Ovarian Choriocarcinoma is CSH1 (Chorionic Somatomammotropin Hormone 1). Affiliated tissues include ovary, liver and brain.

Related Diseases for Gestational Ovarian Choriocarcinoma

Diseases related to Gestational Ovarian Choriocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 non-gestational ovarian choriocarcinoma 32.2 CSH2 CSH1 CPSF4 AFP ADAR
2 choriocarcinoma 31.1 CSH2 CSH1
3 gestational choriocarcinoma 30.6 CSH2 CSH1
4 choriocarcinoma of ovary 28.9 CSH2 CSH1 CPSF4 AFP ADAR
5 non-gestational choriocarcinoma 28.7 CSH2 CSH1 AFP ADAR
6 primary non-gestational choriocarcinoma of ovary 11.9
7 trophoblastic neoplasm 10.2 CSH2 CSH1
8 testicular trophoblastic tumor 10.2 CSH2 CSH1
9 epithelioid trophoblastic tumor 10.1 CSH2 CSH1
10 supine hypotensive syndrome 10.1 CSH2 CSH1
11 cockayne syndrome b 10.1 CSH2 CSH1
12 placental site trophoblastic tumor 10.1 CSH2 CSH1
13 amenorrhea 10.1
14 ovarian cyst 10.1
15 germ cells tumors 10.1
16 persistent fetal circulation syndrome 10.0 CSH2 CSH1
17 liver lipoma 9.8 CEACAM5 AFP
18 malignant sertoli-leydig cell tumor 9.8 CEACAM5 AFP
19 urachal adenocarcinoma 9.8 CEACAM5 AFP
20 immature teratoma of ovary 9.8 CEACAM5 AFP
21 mature teratoma 9.8 CEACAM5 AFP
22 teratoma 9.8 CEACAM5 AFP
23 rectum signet ring adenocarcinoma 9.8 CEACAM5 AFP
24 ovarian mixed germ cell neoplasm 9.8 CEACAM5 AFP
25 renal pelvis adenocarcinoma 9.8 CEACAM5 AFP
26 bile duct cystadenocarcinoma 9.8 CEACAM5 AFP
27 colonic lymphangioma 9.8 CEACAM5 AFP
28 liver lymphoma 9.8 CEACAM5 AFP
29 adult teratoma 9.8 CEACAM5 AFP
30 liver sarcoma 9.8 CEACAM5 AFP
31 benign mesothelioma 9.8 CEACAM5 AFP
32 sarcomatous intrahepatic cholangiocarcinoma 9.8 CEACAM5 AFP
33 mediastinal cancer 9.7 CEACAM5 AFP
34 bile duct cysts 9.7 CEACAM5 AFP
35 ovarian benign neoplasm 9.7 CEACAM5 AFP
36 ovarian germ cell cancer 9.7 CEACAM5 AFP
37 malignant teratoma 9.7 CEACAM5 AFP
38 benign teratoma 9.7 CEACAM5 AFP
39 klatskin's tumor 9.7 CEACAM5 AFP
40 pineoblastoma 9.7 CEACAM5 AFP
41 sex cord-gonadal stromal tumor 9.7 CEACAM5 AFP
42 mixed cell type cancer 9.7 CEACAM5 AFP
43 cystic teratoma 9.6 CEACAM5 AFP
44 tubular adenocarcinoma 9.6 CEACAM5 AFP
45 gestational diabetes 9.6 CSH2 CSH1
46 cystadenoma 9.6 CEACAM5 AFP
47 bile duct adenocarcinoma 9.6 CEACAM5 AFP
48 choriocarcinoma of the testis 9.5 CSH2 CSH1 AFP
49 rh isoimmunization 9.5 CSH2 CSH1 AFP
50 gestational trophoblastic neoplasm 9.5 CSH2 CSH1 AFP

Graphical network of the top 20 diseases related to Gestational Ovarian Choriocarcinoma:



Diseases related to Gestational Ovarian Choriocarcinoma

Symptoms & Phenotypes for Gestational Ovarian Choriocarcinoma

Drugs & Therapeutics for Gestational Ovarian Choriocarcinoma

Search Clinical Trials , NIH Clinical Center for Gestational Ovarian Choriocarcinoma

Genetic Tests for Gestational Ovarian Choriocarcinoma

Anatomical Context for Gestational Ovarian Choriocarcinoma

MalaCards organs/tissues related to Gestational Ovarian Choriocarcinoma:

40
Ovary, Liver, Brain, Lung, Testes, Colon, Placenta

Publications for Gestational Ovarian Choriocarcinoma

Articles related to Gestational Ovarian Choriocarcinoma:

(show all 15)
# Title Authors PMID Year
1
Adolescent non-gestational ovarian choriocarcinoma: report of a case and review of literature. 61
31933999 2019
2
Clinical and ultrasound features of non-gestational ovarian choriocarcinoma. 61
29080278 2018
3
A positive urine pregnancy test (UPT) with adnexal mass; ectopic pregnancy is not the ultimate diagnosis. 61
29558344 2018
4
Extremely Rare Case of Bilateral Pure Primary Non-Gestational Ovarian Choriocarcinoma. 61
29657619 2017
5
Pure non-gestational choriocarcinoma arising in the ovary. 61
29894083 2016
6
Clinicopathological analysis of non-gestational ovarian choriocarcinoma: Report of two cases and review of the literature. 61
27073524 2016
7
A pure non-gestational ovarian choriocarcinoma with delayed solitary brain metastases: Case report and review of the literature. 61
26752905 2015
8
Intra-operative cytodiagnosis of primary ovarian choriocarcinoma with Ki67 immunoexpression. 61
26229256 2015
9
[Clinical analysis of 15 cases of malignant ovarian germ cell tumors with lung metastasis]. 61
22455692 2012
10
Pure non-gestational ovarian choriocarcinoma in a 45,XO/46,XX SRY-negative true hermaphrodite. 61
22070612 2011
11
Management of non-gestational ovarian choriocarcinoma: laparoscopy can be essential. Report of two cases. 61
20561742 2010
12
Pure primary non-gestational ovarian choriocarcinoma: a diagnostic dilemma. 61
20090265 2010
13
Choriocarcinoma of the ovary in a post-menopausal woman. 61
8979475 1996
14
[A case of primary gestational ovarian choriocarcinoma]. 61
8752705 1996
15
[An operated case of gestational ovarian choriocarcinoma formed a huge abdominal tumor]. 61
1856530 1991

Variations for Gestational Ovarian Choriocarcinoma

Expression for Gestational Ovarian Choriocarcinoma

Search GEO for disease gene expression data for Gestational Ovarian Choriocarcinoma.

Pathways for Gestational Ovarian Choriocarcinoma

GO Terms for Gestational Ovarian Choriocarcinoma

Biological processes related to Gestational Ovarian Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.4 CSH2 CSH1
2 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.37 CSH2 CSH1
3 response to nutrient levels GO:0031667 9.32 CSH2 CSH1
4 positive regulation of JAK-STAT cascade GO:0046427 9.26 CSH2 CSH1
5 animal organ development GO:0048513 9.16 CSH2 CSH1
6 growth hormone receptor signaling pathway GO:0060396 8.96 CSH2 CSH1
7 positive regulation of growth GO:0045927 8.62 CSH2 CSH1

Molecular functions related to Gestational Ovarian Choriocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 9.55 CSH2 CSH1 CPSF4 AFP ADAR
2 hormone activity GO:0005179 8.96 CSH2 CSH1
3 growth hormone receptor binding GO:0005131 8.62 CSH2 CSH1

Sources for Gestational Ovarian Choriocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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