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MCID: GST010
MIFTS: 45

Gestational Trophoblastic Neoplasm

Categories: Cancer diseases, Reproductive diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Gestational Trophoblastic Neoplasm

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MalaCards integrated aliases for Gestational Trophoblastic Neoplasm:

Name: Gestational Trophoblastic Neoplasm 12 15
Hydatidiform Mole 12 45 15 74
Gestational Trophoblastic Disease 45 74
Gestational Trophoblastic Neoplasia 12
Gestational Trophoblastic Neoplasms 74
Hydatidiform Mole, Recurrent, 1 74
Molar Pregnancy 12

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Reproductive diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:3590
ICD9CM 36 630
ICD10 34 O01 O01.0 O01.9
SNOMED-CT via HPO 70 17369002 314631008 351814001
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Summaries for Gestational Trophoblastic Neoplasm

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MalaCards based summary : Gestational Trophoblastic Neoplasm, also known as hydatidiform mole, is related to partial hydatidiform mole and hydatidiform mole, recurrent, 1. An important gene associated with Gestational Trophoblastic Neoplasm is H19 (H19 Imprinted Maternally Expressed Transcript), and among its related pathways/superpathways is Nucleotide-binding Oligomerization Domain (NOD) pathway. The drugs Nitroglycerin and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include bone, placenta and bone marrow, and related phenotypes are spontaneous abortion and menometrorrhagia

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Related Diseases for Gestational Trophoblastic Neoplasm

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Diseases related to Gestational Trophoblastic Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 138)
# Related Disease Score Top Affiliating Genes
1 partial hydatidiform mole 34.9 KHDC3L NLRP7
2 hydatidiform mole, recurrent, 1 32.3 CDKN1C H19 KHDC3L NLRP7 PHLDA2
3 choriocarcinoma 31.6 CSH1 CSH2 H19
4 triploidy 31.3 KHDC3L NLRP7
5 gestational choriocarcinoma 31.1 CSH1 H19
6 trophoblastic neoplasm 30.5 CDKN1C CSH1 H19 KHDC3L NLRP2 NLRP7
7 recurrent hydatidiform mole 12.9
8 hydatidiform mole, recurrent, 2 12.9
9 hydatidiform mole, recurrent, 3 12.7
10 hydatidiform mole, recurrent, 4 12.7
11 invasive mole 12.2
12 gestational trophoblastic tumor 11.6
13 placental site trophoblastic tumor 11.4
14 pulmonary arterio-veinous fistula 11.2
15 hyperthyroidism, familial gestational 11.1
16 eclampsia 10.8
17 hyperthyroidism 10.7
18 ectopic pregnancy 10.6
19 pre-eclampsia 10.6
20 placenta praevia 10.5
21 severe pre-eclampsia 10.5
22 pemphigoid gestationis 10.5
23 choroideremia 10.4
24 graves disease 1 10.3
25 infertility 10.3
26 chromosomal triplication 10.3
27 hemihyperplasia, isolated 10.3 CDKN1C H19
28 preeclampsia/eclampsia 1 10.3
29 anencephaly 10.3
30 ovarian hyperstimulation syndrome 10.3
31 joint disorders 10.3
32 leukemia 10.3
33 pemphigus gestationis 10.3
34 thrombosis 10.3
35 endometritis 10.3
36 sarcoma 10.3
37 endometriosis of ovary 10.3
38 nephrotic syndrome 10.3
39 ulceration of vulva 10.3
40 acromegaly 10.3
41 endometriosis 10.3
42 pulmonary tuberculosis 10.3
43 arthropathy 10.3
44 dysgerminoma 10.3
45 ovarian cyst 10.3
46 adenoma 10.3
47 tetraploidy 10.3
48 intrauterine growth retardation, metaphyseal dysplasia, adrenal hypoplasia congenita, and genital anomalies 10.2 CDKN1C NR0B1
49 umbilical hernia 10.2 CDKN1C H19
50 testicular trophoblastic tumor 10.2 CSH1 CSH2

Graphical network of the top 20 diseases related to Gestational Trophoblastic Neoplasm:



Diseases related to Gestational Trophoblastic Neoplasm
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Symptoms & Phenotypes for Gestational Trophoblastic Neoplasm

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Human phenotypes related to Gestational Trophoblastic Neoplasm:

33
# Description HPO Frequency HPO Source Accession
1 spontaneous abortion 33 hallmark (90%) HP:0005268
2 menometrorrhagia 33 hallmark (90%) HP:0400008
3 high maternal serum chorionic gonadotropin 33 hallmark (90%) HP:0011433
Sources

Drugs & Therapeutics for Gestational Trophoblastic Neoplasm

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Drugs for Gestational Trophoblastic Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 181)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Nitroglycerin Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 55-63-0 4510
2 Immunologic Factors Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
3 Vaccines Phase 4,Phase 3,Phase 1
4
Methotrexate Approved Phase 2, Phase 3,Phase 3,Not Applicable 1959-05-2, 59-05-2 126941
5
leucovorin Approved Phase 2, Phase 3,Phase 3,Not Applicable 58-05-9 143 6006
6
Levoleucovorin Approved, Investigational Phase 2, Phase 3,Phase 3 68538-85-2
7
Dactinomycin Approved, Investigational Phase 3,Phase 2 50-76-0 457193 2019
8
Amifostine Approved, Investigational Phase 3 20537-88-6 2141
9
Caspofungin Approved Phase 3,Phase 2 162808-62-0, 179463-17-3 2826718 468682
10
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
11
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Not Applicable 22916-47-8 4189
12
Captopril Approved Phase 3 62571-86-2 44093
13
Cyclophosphamide Approved, Investigational Phase 3,Not Applicable 50-18-0, 6055-19-2 2907
14
Ribavirin Approved Phase 3 36791-04-5 37542
15
Palivizumab Approved, Investigational Phase 3 188039-54-5
16
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
17
Itraconazole Approved, Investigational Phase 3,Not Applicable 84625-61-6 55283
18
Acyclovir Approved Phase 3 59277-89-3 2022
19
Carboplatin Approved Phase 3,Phase 1 41575-94-4 10339178 38904 498142
20
Etoposide Approved Phase 3,Phase 1 33419-42-0 36462
21
Cisplatin Approved Phase 3 15663-27-1 2767 441203 84093
22
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
23
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
24
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
25
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
26
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
27
Polyestradiol phosphate Approved Phase 3 28014-46-2
28
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
29
Mycophenolic acid Approved Phase 3 24280-93-1 446541
30
Calcium Approved, Nutraceutical Phase 2, Phase 3,Phase 3,Not Applicable 7440-70-2 271
31
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3,Phase 3,Not Applicable 59-30-3 6037
32 Dermatologic Agents Phase 2, Phase 3,Phase 3,Not Applicable
33 Immunosuppressive Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
34 Protective Agents Phase 2, Phase 3,Phase 3,Not Applicable
35 Antirheumatic Agents Phase 2, Phase 3,Phase 3,Not Applicable
36 Vitamin B9 Phase 2, Phase 3,Phase 3,Not Applicable
37 Vitamin B Complex Phase 2, Phase 3,Phase 3,Not Applicable
38 Nucleic Acid Synthesis Inhibitors Phase 2, Phase 3,Phase 3
39 Antidotes Phase 2, Phase 3,Phase 3,Not Applicable
40 Antimetabolites, Antineoplastic Phase 2, Phase 3,Phase 3
41 Nutrients Phase 2, Phase 3,Phase 3,Not Applicable
42 Calcium, Dietary Phase 2, Phase 3,Phase 3,Not Applicable
43 Hematinics Phase 2, Phase 3,Phase 3,Not Applicable
44 Hormones Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
45 Trace Elements Phase 2, Phase 3,Phase 3,Not Applicable
46 Folic Acid Antagonists Phase 2, Phase 3,Phase 3
47 Folate Phase 2, Phase 3,Phase 3,Not Applicable
48 Liver Extracts Phase 2, Phase 3,Phase 3,Phase 1
49 Vitamins Phase 2, Phase 3,Phase 3,Not Applicable
50 Bone Density Conservation Agents Phase 2, Phase 3,Phase 3

Interventional clinical trials:

(show top 50) (show all 86)
# Name Status NCT ID Phase Drugs
1 Effectiveness, Safety and Immunogenicity of GSK Biologicals' HPV Vaccine GSK580299 (Cervarix TM) Administered in Healthy Adolescents Completed NCT00534638 Phase 4
2 A Comparison of Single Versus Double Evacuation for Treatment of Hydatidiform Mole Recruiting NCT01630954 Phase 4
3 Surgery Plus Single Agent Chemotherapy Versus Primary Chemotherapy for Gestational Trophoblastic Neoplasms Unknown status NCT02606539 Phase 2, Phase 3 Methotrexate plus folinic acid alone
4 Methotrexate Compared With Dactinomycin in Treating Patients With Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3 Methotrexate
5 RCT on the Efficacy of Methotrexate for the Prevention of GTD Completed NCT01984099 Phase 3 Methotrexate;Vitamin B Complex
6 Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer Completed NCT00058071 Phase 3 amifostine trihydrate
7 Music Therapy or Book Discussion in Improving Quality of Life in Young Patients Undergoing Stem Cell Transplant Completed NCT00305851 Phase 3
8 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
9 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
10 Captopril in Treating Patients Undergoing Bone Marrow or Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
11 Ribavirin With or Without Monoclonal Antibody Therapy in Treating Patients Who Develop RSV Pneumonia Following Peripheral Stem Cell Transplantation Completed NCT00014391 Phase 3 ribavirin
12 Itraconazole Compared With Fluconazole to Prevent Infections in Patients Undergoing Peripheral Stem Cell or Bone Marrow Transplantation Completed NCT00003883 Phase 3 fluconazole;itraconazole
13 Valacyclovir in Preventing Cytomegalovirus Infection in Patients Who Are Undergoing Donor Stem Cell Transplantation Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
14 The Safety Evaluation of the GSK-580299 Vaccine in Women From the Control Group in the Primary NCT00294047 Study Completed NCT01249365 Phase 3
15 Efficacy, Immunogenicity and Safety of GSK Biologicals' HPV GSK 580299 Vaccine in Healthy Chinese Female Subjects Completed NCT00779766 Phase 3
16 Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18 Completed NCT00122681 Phase 3
17 Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor Recruiting NCT02639650 Phase 3 Etoposide;actinomycin D;methotrexate;vincristine;cyclophosphamide;Paclitaxel;Cisplatin;Carboplatin
18 Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia Recruiting NCT03703271 Phase 3 Methotrexate
19 Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6 Recruiting NCT03885388 Phase 2, Phase 3 MTX;MTX+ACTD
20 Methotrexate Single-dose Treatment and Methotrexate/Actinomycin-D Single-dose Treatment in Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01823315 Phase 3 MTX 1;MTX 2
21 Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3 Leucovorin Calcium;Methotrexate
22 Rescue Regimen and High Dose Methotrexate in Management of Presistent Gestational Trophoplastic Neoplasia Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
23 Moxifloxacin in Preventing Bacterial Infections in Patients Who Have Undergone Donor Stem Cell Transplant Terminated NCT00324324 Phase 3 moxifloxacin hydrochloride;Placebo
24 Mycophenolate Mofetil (MMF) for Treatment of Chronic Graft-versus-host Disease (GVHD) Terminated NCT00089141 Phase 3 mycophenolate mofetil;placebo
25 Dactinomycin in Treating Patients With Persistent or Recurrent Gestational Trophoblastic Neoplasia Completed NCT00003688 Phase 2
26 A Trial for Patients With Gestational Trophoblastic Disease Completed NCT00190918 Phase 2 Pemetrexed
27 Second Curettage in Treating Patients With Persistent Non-metastatic Gestational Trophoblastic Tumors Completed NCT00521118 Phase 2
28 Alemtuzumab and Glucocorticoids in Treating Newly Diagnosed Acute Graft-Versus-Host Disease in Patients Who Have Undergone a Donor Stem Cell Transplant Completed NCT00410657 Phase 2 methylprednisolone;prednisone
29 Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors Completed NCT00004157 Phase 2
30 Campath-1H + FK506 and Methylprednisolone for GVHD Completed NCT00109993 Phase 2 methylprednisolone;tacrolimus
31 Lymphocyte Infusion in Treating Patients With Relapsed Cancer After Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00003887 Phase 2
32 Beclomethasone in Treating Patients With Graft-Versus-Host Disease of the Esophagus, Stomach, Small Intestine, or Colon Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
33 Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation Completed NCT00064311 Phase 1, Phase 2 ravuconazole
34 Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer Completed NCT00003408 Phase 2
35 Psychosexual Intervention in Patients With Stage I-III Gynecologic or Breast Cancer Completed NCT01764802 Phase 2
36 Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant Completed NCT00795769 Phase 2 ondansetron
37 Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant Completed NCT00110045 Phase 2 caspofungin acetate
38 Methotrexate and Glucocorticoids in Treating Patients With Newly Diagnosed Acute Graft-Versus-Host Disease After Donor Stem Cell Transplant Completed NCT00357084 Phase 2 methotrexate;methylprednisolone;prednisone
39 Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation Completed NCT00002673 Phase 2
40 Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias Recruiting NCT03135769 Phase 2 Avelumab administration at 10mg/kg
41 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
42 Pemetrexed Disodium in Treating Patients With Recurrent or Persistent Low-Risk Gestational Trophoblastic Tumor After a Molar Pregnancy Terminated NCT00096187 Phase 2 pemetrexed disodium
43 Study of TRC105 and Bevacizumab in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Terminated NCT02664961 Phase 2 TRC105;Bevacizumab
44 Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload Terminated NCT01159067 Phase 2 deferasirox
45 Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions Unknown status NCT00066404 Phase 1
46 Emergency Use of Donor Lymphocytes in Treating Patients Who Have Undergone Donor Stem Cell Transplant and Have Cytomegalovirus Infections Unknown status NCT00769613 Phase 1
47 Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors Completed NCT00003107 Phase 1
48 Prolonged or Standard Infusion of Cefepime Hydrochloride in Treating Patients With Febrile Neutropenia Completed NCT01484015 Phase 1 cefepime hydrochloride
49 Aminocamptothecin in Treating Patients With Advanced Cancer of the Peritoneal Cavity Completed NCT00003548 Phase 1 aminocamptothecin colloidal dispersion
50 Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors Completed NCT00003597 Phase 1 carboplatin;etoposide;ifosfamide

Search NIH Clinical Center for Gestational Trophoblastic Neoplasm

Cochrane evidence based reviews: hydatidiform mole

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Genetic Tests for Gestational Trophoblastic Neoplasm

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Anatomical Context for Gestational Trophoblastic Neoplasm

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MalaCards organs/tissues related to Gestational Trophoblastic Neoplasm:

42
Bone, Placenta, Bone Marrow, Lung, Thyroid, Breast, Testes
Sources

Publications for Gestational Trophoblastic Neoplasm

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Articles related to Gestational Trophoblastic Neoplasm:

(show top 50) (show all 1279)
# Title Authors Year
1
Genetically Related Choriocarcinoma Developing 5 Yr After a Complete Hydatidiform Mole and Simulating a Cornual Ectopic Pregnancy. ( 31033803 )
2019
2
Role of salvage therapy in chemo resistant or recurrent high-risk gestational trophoblastic neoplasm. ( 30700567 )
2019
3
Hysteroscopic Management of Partial Hydatidiform Mole: A Novel Approach to an Old Disease. ( 29631009 )
2019
4
A Novel Mutation in NLRP7 Related to Recurrent Hydatidiform Mole and Reproductive Failure. ( 31037924 )
2019
5
Correction to: ''Bunch of grapes'' in complete hydatidiform mole. ( 30284604 )
2019
6
Do we need post-pregnancy screening with human chorionic gonadotrophin after previous hydatidiform mole to identify patients with recurrent gestational trophoblastic disease? ( 30684876 )
2019
7
The management of hydatidiform mole with lung nodule: a retrospective analysis in 53 patients. ( 30740949 )
2019
8
The potential value of red blood cell distribution width in patients with invasive hydatidiform mole. ( 30883924 )
2019
9
miR-196b inhibits cell migration and invasion through targeting MAP3K1 in hydatidiform mole. ( 30889489 )
2019
10
Tubal hydatidiform mole treated with salpingotomy: A case report. ( 30997056 )
2019
11
Interstitial pregnancy mimicking an invasive hydatidiform mole. ( 31079718 )
2019
12
Choriocarcinoma with multiple lung metastases from complete hydatidiform mole with coexistent fetus during pregnancy. ( 29845692 )
2018
13
Serum angiogenesis profile in gestational trophoblastic neoplasm using multiplex immunoassay. ( 30195618 )
2018
14
HCG-induced hyperthyroidism in a 51-year-old patient with hydatidiform mole. ( 30562809 )
2018
15
Clinical and genetic-epignetic aspects of recurrent hydatidiform mole: A review of literature. ( 29458875 )
2018
16
DNA Genotyping of Nonmolar Donor Egg Pregnancies With Abnormal Villous Morphology: Allele Zygosity Patterns Prevent Misinterpretation as Complete Hydatidiform Mole. ( 28463912 )
2018
17
New insights in the pathophysiology of complete hydatidiform mole. ( 29405964 )
2018
18
A fetus coexisting with a complete hydatidiform mole with trisomy 9 of maternal origin. ( 29436108 )
2018
19
Temporal trends in incidence and outcome of hydatidiform mole: a retrospective cohort study. ( 29451409 )
2018
20
Does a human chorionic gonadotropin level of over 20,000 IU/L four weeks after uterine evacuation for complete hydatidiform mole constitute an indication for chemotherapy for gestational trophoblastic neoplasia? ( 29477553 )
2018
21
A 34-Week Size Uterus with a Complete Hydatidiform Mole: Hook Effect and Severe Anemia with No Vaginal Bleeding. ( 29670785 )
2018
22
Recurrent complete hydatidiform mole: where we are, is there a safe gestational horizon? Opinion and mini-review. ( 29737470 )
2018
23
Accuracy of p57KIP2 compared with genotyping to diagnose complete hydatidiform mole: a systematic review and meta-analysis. ( 29782064 )
2018
24
Prevalence and Factors Associated with Hydatidiform Mole among Patients Undergoing Uterine Evacuation at Mbarara Regional Referral Hospital. ( 29805452 )
2018
25
Invasive hydatidiform mole in the cervix. ( 29875909 )
2018
26
p57KIP2 immunostaining for diagnosis of hydatidiform mole. ( 29904999 )
2018
27
Multiple metastatic gestational trophoblastic disease after a twin pregnancy with complete hydatidiform mole and coexisting fetus, following assisted reproductive technology: Case report and literature review. ( 30122584 )
2018
28
Hydatidiform mole: validity of the registration in the Danish National Patient Registry, the Danish Cancer Registry, and the Danish Pathology Registry 1999-2009. ( 30271218 )
2018
29
Ultrasound and MRI Findings of Twin Pregnancies with Complete Hydatidiform Mole and Coexisting Normal Fetus: Two Case Reports. ( 30282891 )
2018
30
miR-21 Is Overexpressed in Hydatidiform Mole Tissues and Promotes Proliferation, Migration, and Invasion in Choriocarcinoma Cells. ( 27922982 )
2017
31
A pilot randomized controlled clinical trial of second uterine curettage versus usual care to determine the effect of re-curettage on patients' need for chemotherapy among women with low risk, nonmetastatic gestational trophoblastic neoplasm in Urmia, Iran. ( 29033610 )
2017
32
Partial hydatidiform mole in a phenylketonuria patient treated with sapropterin dihydrochloride. ( 27898272 )
2017
33
Prenatal Diagnosis of Twin Pregnancies with Complete Hydatidiform Mole and Coexistent Normal Fetus: A Series of 13 Cases. ( 27522447 )
2017
34
"Bunch of grapes" in complete hydatidiform mole. ( 27933479 )
2017
35
Role of Surgery in the Management of Hydatidiform Mole in Elderly Patients: A Single-Center Clinical Experience. ( 28129241 )
2017
36
HDLive Silhouette Inversion Mode in Diagnosis of Complete Hydatidiform Mole. ( 28133778 )
2017
37
Complete hydatidiform mole with co-existing fetus: Predictors of live birth. ( 28301807 )
2017
38
F10, a novel hydatidiform mole-associated gene, inhibits the paclitaxel sensitivity of A549 lung cancer cells by downregulating BAX and caspase-3. ( 28454434 )
2017
39
Uterine artery Doppler flow velocimetry parameters for predicting gestational trophoblastic neoplasia after complete hydatidiform mole, a prospective cohort study. ( 28591340 )
2017
40
Establishment and characterization of cell lines derived from complete hydatidiform mole. ( 28713902 )
2017
41
Molecular Diagnosis of Placental Hydatidiform Mole: Innovation and Outcomes. ( 28757408 )
2017
42
18F-FDG PET/CT Demonstrating Chorioadenoma Destruens After Evacuation of Complete Hydatidiform Mole. ( 28759528 )
2017
43
Heterotopic Pregnancy Including Intrauterine Normal Gestation and Tubal Complete Hydatidiform Mole: A Case Report and Review of the Literature. ( 28800576 )
2017
44
Prophylactic chemotherapy for hydatidiform mole to prevent gestational trophoblastic neoplasia. ( 28892119 )
2017
45
An unexpected invasive hydatidiform mole in a rudimentary uterine horn: A case report. ( 28927039 )
2017
46
Challenges in the Routine Praxis Diagnosis of Hydatidiform Mole: a Tertiary Health Center Experience. ( 28974845 )
2017
47
Risk Factors for Hydatidiform Mole: Is Husband’s Job a Major Risk Factor? ( 29072060 )
2017
48
Whole-exome sequencing reveals genetic variants in ERC1 and KCNG4 associated with complete hydatidiform mole in Chinese Han women. ( 29088863 )
2017
49
Comparison of different therapeutic strategies for complete hydatidiform mole in women at least 40 years old: a retrospective cohort study. ( 29121880 )
2017
50
A twin pregnancy with a hydatidiform mole and a coexisting live fetus: prenatal diagnosis, treatment, and follow-up. ( 29375907 )
2017
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Variations for Gestational Trophoblastic Neoplasm

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Expression for Gestational Trophoblastic Neoplasm

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Search GEO for disease gene expression data for Gestational Trophoblastic Neoplasm.
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Pathways for Gestational Trophoblastic Neoplasm

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Pathways related to Gestational Trophoblastic Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Nucleotide-binding Oligomerization Domain (NOD) pathway 1
10.24 NLRP2 NLRP7
Sources

GO Terms for Gestational Trophoblastic Neoplasm

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Biological processes related to Gestational Trophoblastic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interleukin-1 beta secretion GO:0050718 9.37 NLRP2 NLRP7
2 positive regulation of JAK-STAT cascade GO:0046427 9.32 CSH1 CSH2
3 adrenal gland development GO:0030325 9.26 CDKN1C NR0B1
4 animal organ development GO:0048513 9.16 CSH1 CSH2
5 growth hormone receptor signaling pathway GO:0060396 8.96 CSH1 CSH2
6 positive regulation of growth GO:0045927 8.62 CSH1 CSH2

Molecular functions related to Gestational Trophoblastic Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth hormone receptor binding GO:0005131 8.62 CSH1 CSH2
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Sources for Gestational Trophoblastic Neoplasm

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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