GTN
MCID: GST059
MIFTS: 32

Gestational Trophoblastic Tumor (GTN)

Categories: Cancer diseases, Rare diseases, Reproductive diseases

Aliases & Classifications for Gestational Trophoblastic Tumor

MalaCards integrated aliases for Gestational Trophoblastic Tumor:

Name: Gestational Trophoblastic Tumor 53 55
Gestational Trophoblastic Disease 53 72
Gestational Trophoblastic Neoplasms 72
Gestational Trophoblastic Neoplasm 53
Gtn 53

Classifications:



External Ids:

UMLS 72 C1135868 C2931618

Summaries for Gestational Trophoblastic Tumor

NIH Rare Diseases : 53 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 59305DefinitionGestational trophoblastic tumors (GTT) are malignant forms of gestational trophoblastic disease. The tumor always follows pregnancy, most often molar pregnancy (hydatidiform mole; see this term). Four histological subtypes have been described: invasive mole, gestational choriocarcinoma, placental site trophoblastic tumor and epithelioid trophoblastic tumor (see these terms).EpidemiologyExact annual incidence is not known but it is estimated to be about 1/1,000,000 women.Clinical descriptionGTTs occur following hydatidiform moles (see this term) (15% of complete moles and about 3% of partial moles), following spontaneous miscarriage (1/150) or childbirth (1/40,000). Indicative signs are an absence of normalization or a secondary elevation of total serum chorionic gonadotropin (hCG) levels after evacuation of a hydatidiform mole (more than 60% of cases), persistent unexplained metrorrhagia following spontaneous miscarriage or voluntary termination of pregnancy (VTP) (about 30% of cases) and very occasionally, unexplained metrorrhagia in the weeks or months following normal childbirth or ectopic pregnancy (about 10% of cases). Exceptionally, metastasis may be a sign of the disease in women of childbearing age.EtiologyThe etiology of gestational trophoblastic tumors is not known. Identification of a GTT is based on a total serum hCG assay, which is recommended following hydatidiform moles in patients with metrorrhagia persisting for more than six weeks after pregnancy, and in any patient of childbearing age who has metastasis (lung, liver, brain, kidney, vagina) with no known primary tumor.Diagnostic methodsDiagnosis of a post-molar GTT relies on one of the following four criteria: stable hCG levels (variation of less than 10%) with at least four weekly assays over a period of at least three weeks (days 1, 7, 14, 21), increase of at least 10% in hCG with at least three weekly assays over at least two weeks (days 1, 7, 14), persistence of detectable hCG values for more than six months following mole evacuation or based on histological diagnosis of a choriocarcinoma.Differential diagnosisGTTs must not be confused with hydatidiform moles (see this term) and, for choriocarcinomas, with non-gestational choriocarcinomas, which are most often ovarian.Management and treatmentAs soon as the diagnosis is made, staging must be performed to identify frequent metastases. Staging involves endovaginal pelvic color doppler ultrasound, pelvic and cerebral MRI, and abdominal/chest CT. A lung X-ray must be performed to calculate the FIGO 2000 score (International Federation of Obstetrics and Gynecology) in case of lung metastasis on CT. This score makes it possible to distinguish between low-risk GTTs (score of 6 or lower) and high-risk GTTs (score of 7 or higher). Management should be multidisciplinary and must be discussed by a panel of physicians in a specialized center. Low-risk tumors are treated by systemic single-agent chemotherapy, e.g. methotrexate (marketing authorization). High-risk tumors are treated first line with systemic multi-agent chemotherapy. Hysterectomy can of course not be considered for first-line treatment in women who wish to become pregnant, unless there is no option. Placental site trophoblastic tumors and epithelioid trophoblastic tumors are special cases: the FIGO score is not appropriate and total hysterectomy is the standard treatment as these tumors are usually chemo-resistant.PrognosisThe overall recovery rate is around 99%. The prognosis is very closely related to the rapidity of diagnosis, the risk level of the tumor (low or high) and the suitability of treatment.Visit the Orphanet disease page for more resources.

MalaCards based summary : Gestational Trophoblastic Tumor, also known as gestational trophoblastic disease, is related to recurrent hydatidiform mole and pulmonary arterio-veinous fistula. An important gene associated with Gestational Trophoblastic Tumor is CGB5 (Chorionic Gonadotropin Subunit Beta 5). The drugs Amifostine and Ribavirin have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and bone marrow.

Related Diseases for Gestational Trophoblastic Tumor

Diseases related to Gestational Trophoblastic Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 119)
# Related Disease Score Top Affiliating Genes
1 recurrent hydatidiform mole 11.5
2 pulmonary arterio-veinous fistula 11.4
3 trophoblastic neoplasm 10.9
4 choriocarcinoma 10.8
5 hydatidiform mole, recurrent, 1 10.7
6 gestational trophoblastic neoplasm 10.7
7 invasive mole 10.6
8 placental site trophoblastic tumor 10.4
9 migraine with or without aura 1 10.4
10 headache 10.4
11 pre-eclampsia 10.4
12 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.2
13 eclampsia 10.2
14 chromosomal triplication 10.2
15 arteriovenous malformation 10.2
16 gestational choriocarcinoma 10.2
17 epithelioid trophoblastic tumor 10.2
18 partial hydatidiform mole 10.2
19 mosaic trisomy 8 10.2
20 leukemia, acute myeloid 10.1
21 neutropenia 10.1
22 gastric adenocarcinoma 10.1
23 stomatitis 10.1
24 acute respiratory distress syndrome 10.1
25 pancreatic cancer 10.1
26 limb ischemia 10.1
27 oral squamous cell carcinoma 10.1
28 migraine without aura 10.1
29 constipation 10.1
30 47,xyy 10.1
31 paroxysmal hemicrania 10.1
32 cerebral aneurysms 10.1
33 graves disease 1 10.1
34 sexual disorder 10.1
35 hemopericardium 10.1
36 pericardial effusion 10.1
37 severe pre-eclampsia 10.1
38 testicular cancer 10.1
39 peritonitis 10.1
40 triploidy 10.1
41 klippel-trenaunay-weber syndrome 10.0
42 clostridium difficile colitis 10.0
43 hypothyroidism 10.0
44 myeloid leukemia 10.0
45 encephalitis 10.0
46 rare surgical neurologic disease 10.0
47 neuroblastoma 1 10.0
48 pulmonary arteriovenous fistulas 10.0
49 polydactyly 10.0
50 meningioma, radiation-induced 10.0

Graphical network of the top 20 diseases related to Gestational Trophoblastic Tumor:



Diseases related to Gestational Trophoblastic Tumor

Symptoms & Phenotypes for Gestational Trophoblastic Tumor

Drugs & Therapeutics for Gestational Trophoblastic Tumor

Drugs for Gestational Trophoblastic Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 167)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amifostine Approved, Investigational Phase 3 20537-88-6 2141
2
Ribavirin Approved Phase 3 36791-04-5 37542
3
Palivizumab Approved, Investigational Phase 3 188039-54-5
4
Miconazole Approved, Investigational, Vet_approved Phase 3 22916-47-8 4189
5
Itraconazole Approved, Investigational Phase 3 84625-61-6 55283
6
Captopril Approved Phase 3 62571-86-2 44093
7
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
8
Caspofungin Approved Phase 3 179463-17-3, 162808-62-0 468682 2826718
9
Acyclovir Approved Phase 3 59277-89-3 2022
10
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
11
Cisplatin Approved Phase 3 15663-27-1 84093 441203 2767
12
Paclitaxel Approved, Vet_approved Phase 3 33069-62-4 36314
13
Cyclophosphamide Approved, Investigational Phase 3 50-18-0, 6055-19-2 2907
14
Vincristine Approved, Investigational Phase 3 57-22-7, 2068-78-2 5978
15
Etoposide Approved Phase 3 33419-42-0 36462
16
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
17
Dactinomycin Approved, Investigational Phase 3 50-76-0 457193 2019
18
Levoleucovorin Approved, Investigational Phase 2, Phase 3 68538-85-2
19
Methotrexate Approved Phase 2, Phase 3 1959-05-2, 59-05-2 126941
20
leucovorin Approved Phase 2, Phase 3 58-05-9 143 6006
21
Ethinyl Estradiol Approved Phase 3 57-63-6 5991
22
Norgestimate Approved, Investigational Phase 3 35189-28-7 6540478
23
Moxifloxacin Approved, Investigational Phase 3 354812-41-2, 151096-09-2 152946
24
Estradiol Approved, Investigational, Vet_approved Phase 3 50-28-2 5757
25
Polyestradiol phosphate Approved Phase 3 28014-46-2
26
Mycophenolic acid Approved Phase 3 24280-93-1 446541
27
Folic acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
28 Liver Extracts Phase 3
29 Radiation-Protective Agents Phase 3
30 Hormone Antagonists Phase 3
31 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
32 HIV Protease Inhibitors Phase 3
33
protease inhibitors Phase 3
34 Antiviral Agents Phase 3
35 Antibodies Phase 3
36 Antibodies, Monoclonal Phase 3
37 Immunoglobulins Phase 3
38 14-alpha Demethylase Inhibitors Phase 3
39 Antifungal Agents Phase 3
40 Cytochrome P-450 CYP3A Inhibitors Phase 3
41 Cytochrome P-450 Enzyme Inhibitors Phase 3
42 Steroid Synthesis Inhibitors Phase 3
43
Hydroxyitraconazole Phase 3
44 Antihypertensive Agents Phase 3
45 Angiotensin-Converting Enzyme Inhibitors Phase 3
46 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
47 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
48 valacyclovir Phase 3
49 Liposomal amphotericin B Phase 3
50 Antiparasitic Agents Phase 3

Interventional clinical trials:

(show top 50) (show all 77)
# Name Status NCT ID Phase Drugs
1 Primary Surgery Plus Single Course Methotrexate Versus Primary Methotrexate for Treatment of Gestational Trophoblastic Neoplasms in Low Risk Cases Above 40y: a Randomized Controled Trial Unknown status NCT02606539 Phase 2, Phase 3 Methotrexate plus folinic acid alone
2 A Randomized Phase III Trial of Weekly Parenteral Methotrexate Versus "Pulsed" Dactinomycin as Primary Management for Low Risk Gestational Trophoblastic Neoplasia Completed NCT00003702 Phase 3 Methotrexate
3 A Randomized Phase III Trial of Amifostine vs. No Treatment for Platinum Induced Peripheral Neuropathy Completed NCT00058071 Phase 3 amifostine trihydrate
4 The Efficacy of Methotrexate for the Prevention of Postmolar Gestational Trophoblastic Disease Among Patients With High-Risk Hydatidiform Mole Completed NCT01984099 Phase 3 Methotrexate;Vitamin B Complex
5 Music Video and Adolescent/Young Adult Resilience During Transplant Completed NCT00305851 Phase 3
6 A Randomized Double-Blind Placebo-Controlled Phase III Study To Evaluate The Safety And Efficacy Of Palivizumab Combined With Aerosolized Ribavirin Compared To Ribavirin Alone To Treat RSV Pneumonia In Patients With Bone Marrow Transplants (BMT) Completed NCT00014391 Phase 3 ribavirin
7 Phase III Study of Captopril in Patients Undergoing Autologous Bone Marrow/Stem Cell Transplantation Completed NCT00004230 Phase 3 captopril;cyclophosphamide
8 A Randomized, Comparative Study of Itraconazole Versus Fluconazole for Prevention of Aspergillus Infections in Peripheral Blood Stem Cell and Marrow Transplant Recipients Completed NCT00003883 Phase 3 fluconazole;itraconazole
9 A Phase III Multicenter Study of Cytomegalovirus Prophylaxis With Valacyclovir for the Prevention of Serious Fungal and Bacterial Infections Among Cytomegalovirus Seronegative Recipients of Cytomegalovirus Seropositive Sx Stem Cell Transplants Completed NCT00045292 Phase 3 acyclovir;acyclovir sodium;valacyclovir
10 A Multicenter, Double-Blind, Randomized, Comparative Study To Evaluate The Safety, Tolerability, And Efficacy Of MK-0991 Versus (Amphotericin B) Liposome For Injection As Empirical Therapy In Patients With Persistent Fever And Neutropenia Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
11 A Strategic Study to Determine the Optimal Moment to Initiate Systemic Antifungal Therapy With Ambisome in Granulocytopenic Cancer Patients With Unexplained Fever Refractory to Empirical Antibacterials Completed NCT00003938 Phase 3 liposomal amphotericin B
12 A Prospective Randomized Multicenter Clinical Control Study of Paclitaxel Plus Cisplatin as the First-line Chemotherapy in High Risk Gestational Trophoblastic Tumor Recruiting NCT02639650 Phase 3 Etoposide;actinomycin D;methotrexate;vincristine;cyclophosphamide;Paclitaxel;Cisplatin;Carboplatin
13 Women's Hospital, Zhejiang University School of Medicine Recruiting NCT03885388 Phase 2, Phase 3 MTX;MTX+ACTD
14 A Prospective Randomized Multicenter Clinical Control Study of Hysteroscopic Repeat Curettage as the Primal Management of Low-risk Postmolar Gestational Trophoblastic Neoplasia Recruiting NCT03703271 Phase 3 Methotrexate
15 A Multicenter, Prospective, Randomized Trial of Methotrexate Single-dose Treatment and Methotrexate/Actinomycin-D Single-dose Treatment in Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01823315 Phase 3 MTX 1;MTX 2
16 A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia Active, not recruiting NCT01535053 Phase 3 Leucovorin Calcium;Methotrexate
17 Comparison Between Rescue Regimen and High Dose Methotrexate in the Managment of Presistent Gestational Trophoplastic Neoplasia :( A Randomized Controlled Trial ) Not yet recruiting NCT03280979 Phase 2, Phase 3 rescue regimen;high dose methotrxate
18 Randomized, Double Blinded, Placebo-Controlled Trial of Antibacterial Prophylaxis for the Prevention of Bacterial Infections in the Post-Engraftment Phase After Allogeneic Hematopoeitic Stem Cell Transplantation Terminated NCT00324324 Phase 3 moxifloxacin hydrochloride;Placebo
19 A Randomized Study to Evaluate The Efficacy of Mycophenolate Mofetil Added to The Systemic Immunosuppressive Regimen First Used For Treatment of Chronic Graft-Versus-Host Disease Terminated NCT00089141 Phase 3 mycophenolate mofetil;placebo
20 A Phase II Trial of Pemetrexed (Alimta) in the Treatment of Recurrent or Persistent Low Risk Gestational Trophoblastic Tumor Completed NCT00190918 Phase 2 Pemetrexed
21 Pulse Actinomycin-D as Salvage Therapy for Failed Low Risk Gestational Trophoblastic Neoplasia Completed NCT00003688 Phase 2
22 A Phase II Study to Evaluate Low-Dose Alemtuzumab as a Glucocorticoid-Sparing Agent for Initial Systemic Treatment of Acute Graft-Versus-Host Disease Completed NCT00410657 Phase 2 methylprednisolone;prednisone
23 Oral Beclomethasone Dipropionate Capsules for Treatment of Intestinal Graft-Versus-Host Disease: Compassionate Use in Patients With Contraindictions to High-Dose Immunosuppressive Therapy Completed NCT00010283 Phase 1, Phase 2 beclomethasone dipropionate
24 Phase II Clinical Trial Incorporating Alemtuzumab (Campath-1H) in Combination With FK506 and Methylprednisolone for Treatment of Severe Acute Graft vs Host Disease Completed NCT00109993 Phase 2 methylprednisolone;tacrolimus
25 Combination of Interleukin 11 (Neumega) With G-CSF to Mobilize Autologous Peripheral Blood Stem Cells (PBSC) Completed NCT00004157 Phase 2
26 Donor Lymphocyte Infusion (DLI) as Adoptive Immunotherapy for Relapse Malignancies After Allogeneic Hematopoietic Transplantation Completed NCT00003887 Phase 2
27 Cytokine-Based Immunotherapy Following High-Dose Chemotherapy and Autologous Stem Cell Transplantation Completed NCT00003408 Phase 2
28 A Phase I-II Safety, Tolerability And Pharmacokinetic Study Of Ravuconazole For Prophylaxis Of Invasive Fungal Infections In Patients Undergoing Non-Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation Completed NCT00064311 Phase 1, Phase 2 ravuconazole
29 Psychosexual Intervention for Gynecologic and Breast Cancer Patients Completed NCT01764802 Phase 2
30 Prevention of DMSO-Related Nausea and Vomiting by Prophylactic Administration of Ondansetron for Patients Receiving Autologous Cryopreserved Peripheral Blood Stem Cells Completed NCT00795769 Phase 2 ondansetron
31 A Phase II Study to Determine the Response to Second Curettage as Initial Management for Persistent Low Risk, Non-metastatic Gestational Trophoblastic Neoplasia Completed NCT00521118 Phase 2
32 A Phase II Study to Evaluate Efficacy and Tolerability of Methotrexate in Combination With Glucocorticoids for the Treatment of Newly Diagnosed Acute Graft-Versus-Host Disease After Nonmyeloablative Hematopoietic Cell Transplantation Completed NCT00357084 Phase 2 methotrexate;methylprednisolone;prednisone
33 A PHASE II STUDY OF CELLULAR ADOPTIVE IMMUNOTHERAPY AS PROPHYLAXIS FOR CYTOMEGALOVIRUS DISEASE AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION Completed NCT00002673 Phase 2
34 A Multicenter, Open, Phase II Study to Estimate the Activity and Safety of Caspofungin (CASP) in the First-Line Treatment of Probable and Proven Invasive Aspergillosis (IA) in Patients With Hematological Malignancies (HM) or Recipients of Autologous Haematopoietic Stem Cell Transplantation and Those With Allogeneic Haematopoietic Stem Cell Transplantation (HSCT) Completed NCT00110045 Phase 2 caspofungin acetate
35 A Phase II Trial of Avelumab in Chemo-resistant Gestational Trophoblastic Neoplasias (GTN) Recruiting NCT03135769 Phase 2 Avelumab administration at 10mg/kg
36 DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors Recruiting NCT02834013 Phase 2
37 Camrelizumab Combined With Apatinib for Recurrent Resistant Gestational Trophoblastic Neoplasia: a Phase 2, Single-arm, Prospective Study Not yet recruiting NCT04047017 Phase 2 Apatinib;Camrelizumab
38 A Phase II Trial of Pemetrexed (ALIMTA®, LY231514, IND #40061) as Salvage Therapy for Failed Low Risk Gestational Trophoblastic Tumor Terminated NCT00096187 Phase 2 pemetrexed disodium
39 A Phase 2A Study of TRC105 (With Option to Add Bevacizumab) in Patients With Refractory Gestational Trophoblastic Neoplasia (GTN) Terminated NCT02664961 Phase 2 TRC105;Bevacizumab
40 Deferasirox Treatment and Labile Plasma Iron in Iron Overloaded Patients Who Have Undergone Allogeneic Hematopoietic Stem Cell Transplantation Terminated NCT01159067 Phase 2 deferasirox
41 A Phase I Clinical Trial of Intrapleural Adenoviral-Mediated Interferon-beta (IFN-ß) Gene Transfer for Pleural Malignancies Unknown status NCT00066404 Phase 1
42 Emergency Access to C.V. pp65 / IE-1 Specific Cytotoxic T Lymphocytes for Recipients of Allogeneic Stem Cell Transplants With Persistant or Therapy Refractory Infections Unknown status NCT00769613 Phase 1
43 A Phase I Trial of Recombinant Human Interleukin-12 After High-Dose Therapy and Autologous Hematopoietic Stem Cell Support Completed NCT00003107 Phase 1
44 Prolonged Infusion Compared to Standard Infusion Cefepime as Empiric Treatment of Febrile Neutropenia: A Pilot Study Completed NCT01484015 Phase 1 cefepime hydrochloride
45 Phase I Study of Intraperitoneal Administration of 9-Amino-20(S)-Camptothecin to Patients With Cancer Predominantly Confined to the Peritoneal Cavity Completed NCT00003548 Phase 1 aminocamptothecin colloidal dispersion
46 A Phase I Study of Thrombopoietin (rhTPO) Plus G-CSF in Children Receiving Ifosfamide, Carboplatin, and Etoposide (I.C.E.) Chemotherapy for Recurrent or Refractory Solid Tumors Completed NCT00003597 Phase 1 carboplatin;etoposide;ifosfamide
47 Donor Mesenchymal Stem Cell Infusion for Treatment of Graft Versus Host Disease: A Phase I Trial Completed NCT00361049 Phase 1
48 Donor Natural Killer Cell Infusion for the Prevention of Relapse or Graft Failure After HLA-Haploidentical Familial Donor Bone Marrow Transplantation-A Phase I Study Completed NCT00569283 Phase 1
49 A Phase I Trial to Examine the Safety, Clinical, Immunologic and Virologic Effects of CMV pp65 Specific Cytotoxic T Lymphocytes for Recipients of Allogeneic Stem Cell Transplants With Persistent or Therapy Refractory Infections Completed NCT00509691 Phase 1
50 Conformation of Beta Human Chorionic Gonadotropin During Chemotherapy for Persistent Gestational Trophoblastic Tumors Using Atomic Force Microscopy and Dual Polarisation Interferometry Unknown status NCT00294177

Search NIH Clinical Center for Gestational Trophoblastic Tumor

Genetic Tests for Gestational Trophoblastic Tumor

Anatomical Context for Gestational Trophoblastic Tumor

MalaCards organs/tissues related to Gestational Trophoblastic Tumor:

41
Bone, Lung, Bone Marrow, Liver, Brain, Placenta, Kidney

Publications for Gestational Trophoblastic Tumor

Articles related to Gestational Trophoblastic Tumor:

(show top 50) (show all 1449)
# Title Authors PMID Year
1
Gestational trophoblastic tumor with liver metastasis after misoprostol abortion. 9 38
18762963 2009
2
Practical issues in the management of low-risk gestational trophoblast tumors. 9 38
19004403 2008
3
Criteria for initiating chemotherapy in patients after evacuation of hydatidiform mole. 9 38
14610317 2003
4
Human chorionic gonadotropin follow-up in patients with molar pregnancy: a time for reevaluation. 9 38
12681878 2003
5
[The c-erbB-related oncoproteins in normal placenta and in gestational trophoblastic diseases (in vitro study)]. 9 38
11424588 2001
6
Expression of epidermal growth factor receptor-related family products in gestational trophoblastic diseases and normal placenta and its relationship with development of postmolar tumor. 9 38
10831347 2000
7
Evaluation of prognostic factors and staging in gestational trophoblastic tumor. 9 38
7970479 1994
8
IFPA meeting 2018 workshop report II: Abnormally invasive placenta; inflammation and infection; preeclampsia; gestational trophoblastic disease and drug delivery. 38
30773233 2019
9
Messages from the placentae across multiple species: A 50 years exploration. 38
31301865 2019
10
Imaging in Gestational Trophoblastic Disease. 38
31375173 2019
11
Single-nucleotide polymorphism microarray detects molar pregnancies in 3% of miscarriages. 38
31395308 2019
12
Leptomeningeal spread of gestational trophoblastic neoplasia in a 19-year old woman. 38
31245524 2019
13
Spontaneous regression of quiescent gestational trophoblastic disease after pregnancy: a case report. 38
31337386 2019
14
Paternal uniparental isodisomy of tyrosine hydroxylase locus at chromosome 11p15.4: spectrum of phenotypical presentations simulating hydatidiform moles. 38
30952972 2019
15
Male primary mediastinal choriocarcinoma with diffuse metastases: A case report. 38
31305456 2019
16
Gestational trophoblastic neoplasia: a meta-analysis evaluating reproductive and obstetrical outcomes after administration of chemotherapy. 38
31253638 2019
17
Changes in Vasodilator-Stimulated Phosphoprotein Phosphorylation, Profilin-1, and Cofilin-1 in Accreta and Protection by DHA. 38
30092744 2019
18
GestaTIonal TrophoblAstic NeoplasIa Ultrasound assessMent: TITANIUM study. 38
31248946 2019
19
Gestational Trophoblastic Disease at Sultan Qaboos University Hospital: Prevalence, Risk Factors, Histological Features, Sonographic Findings, and Outcomes. 38
31110626 2019
20
Genetically Related Choriocarcinoma Developing 5 Yr After a Complete Hydatidiform Mole and Simulating a Cornual Ectopic Pregnancy. 38
31033803 2019
21
Reproductive outcomes following treatment for a gynecological cancer diagnosis: a systematic review. 38
30997658 2019
22
Contraception after pregnancy. 38
31001809 2019
23
Gestational Trophoblastic Disease in Brazil. 38
31049904 2019
24
Hydatidiform molar pregnancy following assisted reproduction. 38
30612209 2019
25
Intensified therapies improve survival and identification of novel prognostic factors for placental-site and epithelioid trophoblastic tumours. 38
30792530 2019
26
The results of treatment with high-dose chemotherapy and peripheral blood stem cell support for gestational trophoblastic neoplasia. 38
30731277 2019
27
A promising therapeutic strategy for metastatic gestational trophoblastic disease: Engineered anticancer gene-expressing stem cells to selectively target choriocarcinoma. 38
30867726 2019
28
Do we need post-pregnancy screening with human chorionic gonadotrophin after previous hydatidiform mole to identify patients with recurrent gestational trophoblastic disease? 38
30684876 2019
29
MALDI-TOF-MS Analysis in the Identification of Urine Proteomic Patterns of Gestational Trophoblastic Disease. 38
30744112 2019
30
Practical applications of DNA genotyping in diagnostic pathology. 38
30638393 2019
31
False diagnosis of and needless therapy for presumed gestational trophoblastic disease in women with an unusual site of residual pregnancy. 38
30409101 2019
32
Differential expression of cyclin E, p63, and Ki-67 in gestational trophoblastic disease and its role in diagnosis and management: A prospective case-control study. 38
30706860 2019
33
Understanding and management of gestational trophoblastic disease. 38
31001418 2019
34
Incidence of gestational trophoblastic disease in South Korea: a longitudinal, population-based study. 38
30809458 2019
35
Is there uniformity in definitions and treatment of gestational trophoblastic disease in Europe? 38
30640691 2019
36
Pulmonary Arteriovenous Malformation After Metastatic Gestational Trophoblastic Tumor. 38
29884426 2019
37
Hydatidiform Moles: Ancillary Techniques to Refine Diagnosis. 38
30500280 2018
38
hCG production by mucinous adenocarcinoma of the ovary in a reproductive aged woman. 38
30533474 2018
39
Naringenin suppresses growth of human placental choriocarcinoma via reactive oxygen species-mediated P38 and JNK MAPK pathways. 38
30466984 2018
40
Update on the diagnosis and management of gestational trophoblastic disease. 38
30306586 2018
41
[Histopathology and clinical aspects of extrauterine pregnancy]. 38
30135973 2018
42
Experience With the Use of an Online Community on Facebook for Brazilian Patients With Gestational Trophoblastic Disease: Netnography Study. 38
30249575 2018
43
Multiple metastatic gestational trophoblastic disease after a twin pregnancy with complete hydatidiform mole and coexisting fetus, following assisted reproductive technology: Case report and literature review. 38
30122584 2018
44
Ultrasound diagnosis of molar pregnancy. 38
30147739 2018
45
Sad Fetus Syndrome: Partial Molar Pregnancy with a Live Fetus. 38
30357025 2018
46
Hyperreactio luteinalis in a monochorionic twin pregnancy complicated by preeclampsia: A case report. 38
30167380 2018
47
Advanced gestational trophoblastic disease: A case report of medical management prior to surgical intervention. 38
30167379 2018
48
Update on the pathology of gestational trophoblastic disease. 38
30129126 2018
49
Surgery and Platinum/Etoposide-Based Chemotherapy for the Treatment of Epithelioid Trophoblastic Tumor. 38
29757875 2018
50
Placenta Site Trophoblastic Tumor and Choriocarcinoma from Previous Cesarean Section Scar: Case Reports. 38
30046213 2018

Variations for Gestational Trophoblastic Tumor

Expression for Gestational Trophoblastic Tumor

Search GEO for disease gene expression data for Gestational Trophoblastic Tumor.

Pathways for Gestational Trophoblastic Tumor

GO Terms for Gestational Trophoblastic Tumor

Sources for Gestational Trophoblastic Tumor

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