GCS
MCID: GNT018
MIFTS: 24

Gianotti Crosti Syndrome (GCS)

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Gianotti Crosti Syndrome

MalaCards integrated aliases for Gianotti Crosti Syndrome:

Name: Gianotti Crosti Syndrome 52
Acrodermatitis, Infantile Lichenoid 52
Papular Acrodermatitis of Childhood 52
Acrodermatitis, Papular Infantile 52
Crosti-Gianotti Syndrome 52
Gianotti-Crosti Syndrome 71
Gcs 52
Pac 52
Pas 52

Classifications:



External Ids:

ICD10 32 L44.4
UMLS 71 C0263372

Summaries for Gianotti Crosti Syndrome

NIH Rare Diseases : 52 Gianotti Crosti syndrome (GCS) is a rare childhood skin condition characterized by a papular rash with blisters on the skin of the legs, buttocks, and arms. It typically affects children between 9 months and 9 years of age. Skin lesions typically last at least 10 days and often last for several weeks. The lesions are usually preceded by an underlying infection (usually a virus ), which may cause associated symptoms such as low-grade fever, sore throat, or symptoms of an upper respiratory infection. When GCS is associated with hepatitis B , Epstein-Barr , or cytomegalovirus (CMV) infection, acute hepatitis may also occur. GCS is thought to be a hypersensitive response to the underlying infection. While in many countries the underlying cause is hepatitis B, this is rarely the cause in North America. GCS typically does not require treatment and goes away on its own within 1 to 3 months. In some cases, a mild topical steroid cream may be prescribed to relieve itching.

MalaCards based summary : Gianotti Crosti Syndrome, also known as acrodermatitis, infantile lichenoid, is related to gastric cancer and camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Affiliated tissues include skin, bone marrow and bone.

Wikipedia : 74 Gianotti-Crosti syndrome (/d??'n?ti 'kr?sti/), also known as infantile papular acrodermatitis, papular... more...

Related Diseases for Gianotti Crosti Syndrome

Diseases related to Gianotti Crosti Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 673)
# Related Disease Score Top Affiliating Genes
1 gastric cancer 11.8
2 camptodactyly-arthropathy-coxa vara-pericarditis syndrome 11.6
3 gaucher disease, type i 11.5
4 classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency 11.3
5 camptodactyly syndrome, guadalajara, type i 11.2
6 guanylate cyclase 2e, pseudogene 11.2
7 bile acid synthesis defect, congenital, 2 11.2
8 lathosterolosis 11.2
9 bile acid synthesis defect, congenital, 1 11.2
10 aminoacylase 1 deficiency 11.2
11 testicular cancer 11.2
12 acrodermatitis 11.0
13 exanthem 10.9
14 hepatitis b 10.9
15 rapidly involuting congenital hemangioma 10.9
16 triiodothyronine receptor auxiliary protein 10.7
17 poliomyelitis 10.6
18 ige responsiveness, atopic 10.5
19 dermatitis, atopic 10.5
20 pertussis 10.5
21 tetanus 10.5
22 hepatitis 10.5
23 dermatitis 10.5
24 influenza 10.5
25 chickenpox 10.5
26 diphtheria 10.5
27 hepatitis a 10.5
28 pityriasis rosea 10.5
29 ocular motor apraxia 10.4
30 pfeiffer syndrome 10.4
31 immune deficiency disease 10.4
32 allergic rhinitis 10.4
33 mumps 10.4
34 bacterial infectious disease 10.4
35 allergic conjunctivitis 10.4
36 urticaria 10.4
37 pharyngitis 10.4
38 rhinitis 10.4
39 conjunctivitis 10.4
40 measles 10.4
41 cytomegalovirus infection 10.4
42 dental caries 10.4
43 viral hepatitis 10.3
44 meester-loeys syndrome 10.3
45 dentinogenesis imperfecta type 2 10.3
46 acute liver failure 10.3
47 polycystic kidney disease 10.2
48 chromophobe renal cell carcinoma 10.2
49 renal oncocytoma 10.2
50 constipation 10.2

Graphical network of the top 20 diseases related to Gianotti Crosti Syndrome:



Diseases related to Gianotti Crosti Syndrome

Symptoms & Phenotypes for Gianotti Crosti Syndrome

Drugs & Therapeutics for Gianotti Crosti Syndrome

Search Clinical Trials , NIH Clinical Center for Gianotti Crosti Syndrome

Genetic Tests for Gianotti Crosti Syndrome

Anatomical Context for Gianotti Crosti Syndrome

MalaCards organs/tissues related to Gianotti Crosti Syndrome:

40
Skin, Bone Marrow, Bone, Lymph Node

Publications for Gianotti Crosti Syndrome

Articles related to Gianotti Crosti Syndrome:

(show top 50) (show all 230)
# Title Authors PMID Year
1
Cutaneous manifestations of HAV, HBV, HCV. 61
31804053 2019
2
Gianotti-Crosti syndrome (papular acrodermatitis of childhood) in the era of a viral recrudescence and vaccine opposition. 61
31134587 2019
3
[Gianotti-Crosti syndrome-like reaction secondary to Molluscum contagiosum]. 61
31635922 2019
4
Case of Gianotti-Crosti syndrome following varicella zoster virus vaccination. 61
29897138 2019
5
Gianotti-Crosti syndrome and atypical hand-foot-mouth disease: two distinct entities or two manifestation of the same infection? 61
29963801 2018
6
Atypical Gianotti-Crosti syndrome. 61
29723358 2018
7
[Acute skin infections and their imitators in children : A photo quiz]. 61
28914333 2017
8
[Paraviral exanthems]. 61
28194482 2017
9
A case-control study on the association of pulse oral poliomyelitis vaccination and Gianotti-Crosti syndrome. 61
27943306 2017
10
Gianotti-Crosti syndrome: a case report of a teenager. 61
28300930 2016
11
Is Gianotti-Crosti Syndrome Associated with Atopy? A Case-Control Study and a Postulation on the Intrinsic Host Factors in Gianotti-Crosti Syndrome. 61
27339179 2016
12
Paraviral exanthems. 61
27144956 2016
13
Gianotti-Crosti syndrome as presenting sign of cytomegalovirus infection: A case report and a critical appraisal of its possible cytomegalovirus etiology. 61
27017141 2016
14
Gianotti-Crosti Syndrome and Erythema Nodosum: Two Distinct Entities or Two Manifestations of the Same Infection? 61
26896156 2016
15
Pityriasis Rosea, Gianotti-Crosti Syndrome, Asymmetric Periflexural Exanthem, Papular-Purpuric Gloves and Socks Syndrome, Eruptive Pseudoangiomatosis, and Eruptive Hypomelanosis: Do Their Epidemiological Data Substantiate Infectious Etiologies? 61
27103975 2016
16
Gianotti-Crosti syndrome associated with Ebstein-Barr virus and Parvovirus B-19 coinfection in a male adult: case report and review of the literature. 61
25034095 2016
17
Unusual Presentation of Gianotti-Crosti Syndrome due to Epstein-Barr Virus Infection. 61
28050291 2016
18
Pediatric idiopathic hypereosinophilic syndrome with Gianotti-Crosti syndrome: a novel presentation. 61
24738625 2015
19
Viral Skin Diseases. 61
26612372 2015
20
Gianotti-Crosti Syndrome following immunization in an 18 months old child. 61
26751677 2015
21
Renal disease in patients infected with hepatitis B virus. 61
27509699 2015
22
[Skin disorder as an indication of viral infection]. 61
26083843 2015
23
Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature. 61
26067570 2015
24
Gianotti-Crosti syndrome in a postpartum adult. 61
24738477 2015
25
The diagnostic criteria of pityriasis rosea and Gianotti-Crosti syndrome - a protocol to establish diagnostic criteria of skin diseases. 61
26517103 2015
26
Spontaneous and antiviral-induced cutaneous lesions in chronic hepatitis B virus infection. 61
25400473 2014
27
Visual diagnosis: 12-month-old boy with persistent rash and lymphadenopathy. 61
25274975 2014
28
Ferdinando Gianotti and the papular acrodermatitis of childhood: a scientist against all the odds. 61
24827010 2014
29
Macular exanthema in a child with rotavirus gastroenteritis: a case report. 61
24584801 2014
30
Epstein-Barr virus and skin manifestations in childhood. 61
24073903 2013
31
[Adult Gianotti-Crosti syndrome caused by hepatitis B]. 61
24005107 2013
32
A 22-month-old girl with lesions on the face and extremities. 61
23316831 2013
33
Human β-defensin 4 expression in Gianotti-Crosti. 61
23683486 2013
34
Photo quiz. Papular rash in a child after a fever. Gianotti-Crosti syndrome. 61
23317026 2013
35
Gianotti-Crosti syndrome following childhood vaccinations. 61
22141410 2013
36
Hemorrhagic Gianotti-Crosti Syndrome in a One and Half Month old Infant: An Extremely Unusual Presentation. 61
23372217 2013
37
Experience with molluscum contagiosum and associated inflammatory reactions in a pediatric dermatology practice: the bump that rashes. 61
22911012 2012
38
Gianotti-Crosti syndrome after childhood vaccination. 61
22352961 2012
39
Gianotti-Crosti syndrome: case report of a pruritic acral exanthema in a child. 61
22872825 2012
40
[Mother-to-child HBV transmission--atypical course of hepatitis B in an infant]. 61
22971660 2012
41
Gianotti-Crosti syndrome: a case report in an adult. 61
22611743 2012
42
Gianotti-Crosti syndrome associated with hepatitis A and influenza vaccination. 61
22371989 2012
43
Gianotti-Crosti syndrome, pityriasis rosea, asymmetrical periflexural exanthem, unilateral mediothoracic exanthem, eruptive pseudoangiomatosis, and papular-purpuric gloves and socks syndrome: a brief review and arguments for diagnostic criteria. 61
24470919 2012
44
[A newborn with an acute itchy skin rash]. 61
23191962 2012
45
Giannoti-Crosti syndrome associated with type A influenza. 61
21453305 2011
46
Gianotti-Crosti Syndrome Following Novel Influenza A (H1N1) Vaccination. 61
22148034 2011
47
Recurrent Gianotti-Crosti syndrome. 61
21920247 2011
48
Atypical Gianotti-Crosti syndrome following administration of the AS03-adjuvanted H1N1 vaccine. 61
21920234 2011
49
Gianotti-Crosti syndrome after H1N1-influenza vaccine. 61
21554384 2011
50
Acute disseminated erythematous papulovesicular skin lesions in a 7-year-old child: a quiz. Diagnosis: vesicular Gianotti-Crosti syndrome. 61
21103846 2011

Variations for Gianotti Crosti Syndrome

Expression for Gianotti Crosti Syndrome

Search GEO for disease gene expression data for Gianotti Crosti Syndrome.

Pathways for Gianotti Crosti Syndrome

GO Terms for Gianotti Crosti Syndrome

Sources for Gianotti Crosti Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....