MCID: GNT005
MIFTS: 27

Giant Hemangioma

Categories: Blood diseases

Aliases & Classifications for Giant Hemangioma

MalaCards integrated aliases for Giant Hemangioma:

Name: Giant Hemangioma 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:5774
NCIt 50 C27777
UMLS 70 C1333817

Summaries for Giant Hemangioma

MalaCards based summary : Giant Hemangioma is related to hemangioma and thrombocytopenia. An important gene associated with Giant Hemangioma is IFNA2 (Interferon Alpha 2), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Formation of Fibrin Clot (Clotting Cascade). Affiliated tissues include liver, heart and spleen.

Related Diseases for Giant Hemangioma

Diseases related to Giant Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 218)
# Related Disease Score Top Affiliating Genes
1 hemangioma 31.3 IFNA2 F3 F2
2 thrombocytopenia 30.1 SERPINC1 IFNA2 F3 F2
3 purpura 29.7 SERPINC1 F3 F2
4 disseminated intravascular coagulation 29.6 SERPINF2 SERPINC1 F3 F2
5 hemolytic anemia 29.5 IFNA2 F3 F2
6 thrombocytosis 29.5 SERPINC1 F3 F2
7 thrombosis 29.1 SERPINF2 SERPINC1 F3 F2
8 afibrinogenemia, congenital 29.1 SERPINF2 SERPINC1 F3 F2
9 budd-chiari syndrome 28.8 SERPINC1 F3 F2 AFP
10 hemangioma-thrombocytopenia syndrome 10.4
11 hemangioma of liver 10.3
12 achenbach syndrome 10.2 F3 F2
13 renal pelvis squamous cell carcinoma 10.2 F3 F2
14 synovial angioma 10.2 F3 F2
15 femoral neuropathy 10.2 F3 F2
16 emphysematous cholecystitis 10.2 F3 F2
17 hemopneumothorax 10.2 F3 F2
18 cerebral falx meningioma 10.2 F3 F2
19 ankylosing spondylitis 1 10.2 F3 F2
20 pulmonary embolism and infarction 10.2 F3 F2
21 acute pulmonary heart disease 10.2 F3 F2
22 epidural abscess 10.2 F3 F2
23 lemierre's syndrome 10.2 F3 F2
24 acute cor pulmonale 10.2 F3 F2
25 posterior cerebral artery infarction 10.2 F3 F2
26 gastric hemangioma 10.2 F3 F2
27 hemopericardium 10.2 F3 F2
28 qualitative platelet defect 10.2 F3 F2
29 mediastinitis 10.2 F3 F2
30 cerebral sinovenous thrombosis 10.2 F3 F2
31 acquired von willebrand syndrome 10.2 F3 F2
32 active peptic ulcer disease 10.2 F3 F2
33 splenic sequestration 10.2 F3 F2
34 acute hemorrhagic encephalitis 10.2 F3 F2
35 hepatitis d 10.2 IFNA2 F2
36 parametritis 10.2 F3 F2
37 hantavirus pulmonary syndrome 10.1 F3 F2
38 analbuminemia 10.1 F3 F2
39 hemarthrosis 10.1 F3 F2
40 cardiac tamponade 10.1 F3 F2
41 cavernous hemangioma 10.1
42 anuria 10.1 F3 F2
43 cecal disease 10.1 F3 F2
44 tricuspid valve disease 10.1 F3 F2
45 tricuspid valve insufficiency 10.1 F3 F2
46 primary thrombocytopenia 10.1 F3 F2
47 factor v deficiency 10.1 F3 F2
48 aortic valve insufficiency 10.1 F3 F2
49 factor x deficiency 10.1 F3 F2
50 thrombasthenia 10.1 F3 F2

Graphical network of the top 20 diseases related to Giant Hemangioma:



Diseases related to Giant Hemangioma

Symptoms & Phenotypes for Giant Hemangioma

Drugs & Therapeutics for Giant Hemangioma

Search Clinical Trials , NIH Clinical Center for Giant Hemangioma

Genetic Tests for Giant Hemangioma

Anatomical Context for Giant Hemangioma

MalaCards organs/tissues related to Giant Hemangioma:

40
Liver, Heart, Spleen, Placenta, Tongue, Eye, Adrenal Gland

Publications for Giant Hemangioma

Articles related to Giant Hemangioma:

(show top 50) (show all 204)
# Title Authors PMID Year
1
Proton beam therapy for a giant hepatic hemangioma: A case report and literature review. 61
33665385 2021
2
Liver Transplantation for Rapidly Progressive Giant Hepatic Hemangioma With Diffuse Hemangiomatosis. 61
33535936 2021
3
Spontaneous internal hemorrhage of a giant hepatic hemangioma with infection: a case report and literature review. 61
33284661 2020
4
Robotic Left Hepatectomy for Giant Hemangioma: Technical Approach in Minimally Invasive Liver Surgery. 61
33377813 2020
5
Efficacy and factors affecting the choice of enucleation and liver resection for giant hemangioma: a retrospective propensity score-matched study. 61
33160352 2020
6
Pyrexia of Unknown Origin: An Atypical Presentation of Hepatic Hemangioma. 61
33335986 2020
7
Aggressive and giant hemangioma of the lumbar spine. 61
32360831 2020
8
Giant Hemangioma of the Mediastinum. 61
32027806 2020
9
Detection and monitoring of postinterventional success and complications of the liver using contrast-enhanced ultrasound (CEUS) - a case report after interventional treatment of a giant hemangioma. 61
30534665 2018
10
Neonatal giant hepatic hemangioma: A case report. 61
30334996 2018
11
[A case of infant giant hemangioma]. 61
30347541 2018
12
[Streptococcal toxic shock syndrome caused by Streptococcus pyogenes: a retrospective study of 15 pediatric cases]. 61
30078239 2018
13
Surgical Management of Giant Hepatic Hemangioma: Single Center's Experience with 144 Patients. 61
29488123 2018
14
[Giant hepatic hemangioma, an uncommon presentation of a frequent disease]. 61
30118469 2018
15
Coexistence of Kasabach-Merritt Syndrome and placental chorioangioma in a premature infant. 61
29991142 2018
16
Giant hemangioma of anterior mediastinum mimicking bilateral pleural effusion. 61
29354184 2017
17
Propranolol in the preoperative treatment of Kasabach-Merritt syndrome: a case report. 61
29073926 2017
18
Intratumoral coagulation by radiofrequency ablation facilitated the laparoscopic resection of giant hepatic hemangioma: a surgical technique report of two cases. 61
28881707 2017
19
Transoral ultrasonic surgery of pharyngolaryngeal giant hemangioma after ethylene-vinyl alcohol copolymer (Onyx) embolization. 61
28263419 2017
20
Characteristics and operative treatment of extremely giant liver hemangioma >20 cm. 61
28126252 2017
21
Pure laparoscopic right hepatectomy for giant hemangioma using anterior approach. 61
27620909 2017
22
A rare case of intra and extra testicular varicocele caused by giant hemangioma of liver. 61
30005524 2016
23
Enucleation is Better for a Giant Hemangioma Proximal to the Hepatic Portal Vascular Structures. 61
27574349 2016
24
Resection of Giant Hemangioma of the Tongue Utilizing a Miniature Tourniquet Technique. 61
27391511 2016
25
Successful treatment by coil embolization for infantile hemangioma with Kasabach-Meritt syndrome of newborn. 61
26044386 2015
26
Tumor size is not a criterion for resection during the management of giant hemangioma of the liver. 61
25923944 2015
27
Management of Giant Hepatic Hemangioma in Atypical Localization; Report of a Case and Literature Review. 61
26146110 2015
28
Enucleation of a Giant Hemangioma of Liver: Old School Revisited. 61
26844001 2015
29
Giant hemangioma causing budd-Chiari syndrome. 61
25755587 2014
30
Feasibility of laparoscopic liver resection for giant hemangioma of greater than 6 cm in diameter. 61
26155263 2014
31
Right hepatectomy for giant cavernous hemangioma with diffuse hemangiomatosis around Glisson's capsule. 61
25009410 2014
32
[Pingyangmycin injection under suspension laryngoscopy for giant hemangioma at hypopharynx and laryngeal in 12 cases hemangioma at hypopharynx and laryngeal in 12 cases]. 61
25195276 2014
33
Extended hemangioma from pharynx to esophagus that could be misdiagnosed as an esophageal varix on endoscopy. 61
24164602 2013
34
Giant mesenteric hemangioma of cavernous and venous mixed type: a rare case report. 61
24168418 2013
35
[Giant hemangioma of the rib]. 61
23917134 2013
36
Giant hemangioma presenting as a scalp mass leading to a craniofacial deformity. 61
24431843 2013
37
Management of hemangioma of the liver: surgical therapy or observation? 61
23354918 2013
38
Successful liver resection in a giant hemangioma with intestinal obstruction after embolization. 61
23704832 2013
39
Management of giant liver hemangiomas: an update. 61
23445235 2013
40
Spontaneous rupture of giant liver hemangioma: case report. 61
23539918 2013
41
Airway management in a toddler with a giant hemangioma of the tongue. 61
23429176 2012
42
Recurrent giant hemangiomas of liver: Report of two rare cases with literature review. 61
23494295 2012
43
Resection for progressively growing giant hemangioma of anterior abdominal wall. 61
22808765 2012
44
Pre-operative arterial embolization of symptomatic giant hemangioma of the liver. 61
22691287 2012
45
[The treatment of the sponateneous biloma and choledocholithiasis after the liver resection on the reason of the giant hemangioma]. 61
22810542 2012
46
[Successful anesthetic management for resection of a giant hepatic hemangioma with Kasabach-Merritt syndrome using FloTrac system]. 61
22175175 2011
47
Resection of giant liver hemangioma in a pregnant woman with coagulopathy: Case report and literature review. 61
22905301 2011
48
Surgical Management for Giant liver Hemangiomas Greater Than 20 cm in Size. 61
21814606 2011
49
Hepatic angiomyolipoma with a giant hemangioma. 61
22041879 2011
50
Robotic right hepatectomy for giant hemangioma in a Jehovah's Witness. 61
20596878 2011

Variations for Giant Hemangioma

Expression for Giant Hemangioma

Search GEO for disease gene expression data for Giant Hemangioma.

Pathways for Giant Hemangioma

GO Terms for Giant Hemangioma

Cellular components related to Giant Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.63 SERPINF2 SERPINC1 IFNA2 F3 F2 AFP
2 endoplasmic reticulum lumen GO:0005788 9.5 SERPINC1 F2 AFP
3 blood microparticle GO:0072562 9.43 SERPINF2 SERPINC1 F2
4 extracellular space GO:0005615 9.43 SERPINF2 SERPINC1 IFNA2 F3 F2 AFP
5 collagen-containing extracellular matrix GO:0062023 9.02 SERPINF2 SERPINC1 IFNA2 F3 F2

Biological processes related to Giant Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.54 SERPINC1 F2 AFP
2 acute-phase response GO:0006953 9.43 SERPINF2 F2
3 positive regulation of collagen biosynthetic process GO:0032967 9.4 SERPINF2 F2
4 fibrinolysis GO:0042730 9.32 SERPINF2 F2
5 regulation of blood coagulation GO:0030193 9.26 SERPINC1 F2
6 negative regulation of fibrinolysis GO:0051918 9.16 SERPINF2 F2
7 hemostasis GO:0007599 9.13 SERPINC1 F3 F2
8 blood coagulation GO:0007596 8.92 SERPINC1 IFNA2 F3 F2

Molecular functions related to Giant Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protease binding GO:0002020 8.8 SERPINF2 SERPINC1 F3

Sources for Giant Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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