MCID: GNT005
MIFTS: 27

Giant Hemangioma

Categories: Blood diseases

Aliases & Classifications for Giant Hemangioma

MalaCards integrated aliases for Giant Hemangioma:

Name: Giant Hemangioma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:5774
NCIt 49 C27777
UMLS 71 C1333817

Summaries for Giant Hemangioma

MalaCards based summary : Giant Hemangioma is related to hemangioma and cavernous hemangioma. An important gene associated with Giant Hemangioma is SERPINA3 (Serpin Family A Member 3), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Formation of Fibrin Clot (Clotting Cascade). Affiliated tissues include liver, heart and spleen.

Related Diseases for Giant Hemangioma

Diseases related to Giant Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 223)
# Related Disease Score Top Affiliating Genes
1 hemangioma 31.4 IFNA2 F3 F2
2 cavernous hemangioma 30.1 SERPINA3 F2 AFP
3 thrombocytopenia 30.0 SERPINC1 IFNA2 F3 F2
4 disseminated intravascular coagulation 30.0 SERPINC1 F3 F2
5 purpura 29.7 SERPINC1 F3 F2
6 thrombosis 29.5 SERPINC1 F3 F2
7 budd-chiari syndrome 29.4 SERPINC1 F3 F2
8 afibrinogenemia, congenital 29.4 SERPINC1 F3 F2
9 thrombocytosis 29.4 SERPINC1 F3 F2
10 blood coagulation disease 29.1 SERPINC1 SERPINA3 F3 F2
11 hemangioma-thrombocytopenia syndrome 10.4
12 hemoglobin e disease 10.3 SERPINA3 F2
13 hemangioma of liver 10.3
14 cecal disease 10.3 SERPINA3 F2
15 aspiration pneumonitis 10.3 SERPINA3 F3
16 gastric hemangioma 10.3 F3 F2
17 synovial angioma 10.3 F3 F2
18 renal pelvis squamous cell carcinoma 10.3 F3 F2
19 emphysematous cholecystitis 10.3 F3 F2
20 femoral neuropathy 10.3 F3 F2
21 lemierre's syndrome 10.3 F3 F2
22 platelet aggregation, spontaneous 10.2 SERPINC1 SERPINA3
23 qualitative platelet defect 10.2 F3 F2
24 cerebral sinovenous thrombosis 10.2 F3 F2
25 retinal artery occlusion 10.2 SERPINC1 F2
26 hepatitis d 10.2 IFNA2 F2
27 hemopericardium 10.2 F3 F2
28 intracranial hypotension 10.2 F3 F2
29 splenic sequestration 10.2 F3 F2
30 active peptic ulcer disease 10.2 F3 F2
31 spinal cord infarction 10.2 SERPINC1 F2
32 hantavirus pulmonary syndrome 10.2 F3 F2
33 analbuminemia 10.2 F3 F2
34 intracranial hypertension, idiopathic 10.2 F3 F2
35 sudden sensorineural hearing loss 10.2 SERPINC1 F2
36 hemarthrosis 10.2 F3 F2
37 lateral sinus thrombosis 10.2 SERPINC1 F2
38 waterhouse-friderichsen syndrome 10.2 SERPINC1 F2
39 von willebrand disease, type 1 10.2 F3 F2
40 thrombasthenia 10.2 F3 F2
41 cavernous sinus thrombosis 10.2 SERPINC1 F2
42 cardiac tamponade 10.2 F3 F2
43 encephalopathy, familial, with neuroserpin inclusion bodies 10.2 SERPINC1 SERPINA3
44 livedoid vasculitis 10.2 SERPINC1 F2
45 thoracic outlet syndrome 10.2 SERPINC1 F2
46 anuria 10.2 F3 F2
47 prothrombin deficiency, congenital 10.2 SERPINC1 F2
48 trophoblastic neoplasm 10.2 SERPINA3 CGA
49 factor x deficiency 10.2 F3 F2
50 tricuspid valve insufficiency 10.2 F3 F2

Graphical network of the top 20 diseases related to Giant Hemangioma:



Diseases related to Giant Hemangioma

Symptoms & Phenotypes for Giant Hemangioma

Drugs & Therapeutics for Giant Hemangioma

Search Clinical Trials , NIH Clinical Center for Giant Hemangioma

Genetic Tests for Giant Hemangioma

Anatomical Context for Giant Hemangioma

MalaCards organs/tissues related to Giant Hemangioma:

40
Liver, Heart, Spleen, Kidney, Tongue, Eye, Lung

Publications for Giant Hemangioma

Articles related to Giant Hemangioma:

(show top 50) (show all 197)
# Title Authors PMID Year
1
Giant Hemangioma of the Mediastinum. 61
32027806 2020
2
Detection and monitoring of postinterventional success and complications of the liver using contrast-enhanced ultrasound (CEUS) - a case report after interventional treatment of a giant hemangioma. 61
30534665 2018
3
[A case of infant giant hemangioma]. 61
30347541 2018
4
Neonatal giant hepatic hemangioma: A case report. 61
30334996 2018
5
[Streptococcal toxic shock syndrome caused by Streptococcus pyogenes: a retrospective study of 15 pediatric cases]. 61
30078239 2018
6
Surgical Management of Giant Hepatic Hemangioma: Single Center's Experience with 144 Patients. 61
29488123 2018
7
[Giant hepatic hemangioma, an uncommon presentation of a frequent disease]. 61
30118469 2018
8
Coexistence of Kasabach-Merritt Syndrome and placental chorioangioma in a premature infant. 61
29991142 2018
9
Giant hemangioma of anterior mediastinum mimicking bilateral pleural effusion. 61
29354184 2017
10
Propranolol in the preoperative treatment of Kasabach-Merritt syndrome: a case report. 61
29073926 2017
11
Intratumoral coagulation by radiofrequency ablation facilitated the laparoscopic resection of giant hepatic hemangioma: a surgical technique report of two cases. 61
28881707 2017
12
Transoral ultrasonic surgery of pharyngolaryngeal giant hemangioma after ethylene-vinyl alcohol copolymer (Onyx) embolization. 61
28263419 2017
13
Characteristics and operative treatment of extremely giant liver hemangioma >20 cm. 61
28126252 2017
14
Pure laparoscopic right hepatectomy for giant hemangioma using anterior approach. 61
27620909 2017
15
A rare case of intra and extra testicular varicocele caused by giant hemangioma of liver. 61
30005524 2016
16
Enucleation is Better for a Giant Hemangioma Proximal to the Hepatic Portal Vascular Structures. 61
27574349 2016
17
Resection of Giant Hemangioma of the Tongue Utilizing a Miniature Tourniquet Technique. 61
27391511 2016
18
Successful treatment by coil embolization for infantile hemangioma with Kasabach-Meritt syndrome of newborn. 61
26044386 2015
19
Tumor size is not a criterion for resection during the management of giant hemangioma of the liver. 61
25923944 2015
20
Management of Giant Hepatic Hemangioma in Atypical Localization; Report of a Case and Literature Review. 61
26146110 2015
21
Enucleation of a Giant Hemangioma of Liver: Old School Revisited. 61
26844001 2015
22
Giant hemangioma causing budd-Chiari syndrome. 61
25755587 2014
23
Feasibility of laparoscopic liver resection for giant hemangioma of greater than 6 cm in diameter. 61
26155263 2014
24
Right hepatectomy for giant cavernous hemangioma with diffuse hemangiomatosis around Glisson's capsule. 61
25009410 2014
25
[Pingyangmycin injection under suspension laryngoscopy for giant hemangioma at hypopharynx and laryngeal in 12 cases hemangioma at hypopharynx and laryngeal in 12 cases]. 61
25195276 2014
26
Extended hemangioma from pharynx to esophagus that could be misdiagnosed as an esophageal varix on endoscopy. 61
24164602 2013
27
Giant mesenteric hemangioma of cavernous and venous mixed type: a rare case report. 61
24168418 2013
28
[Giant hemangioma of the rib]. 61
23917134 2013
29
Giant hemangioma presenting as a scalp mass leading to a craniofacial deformity. 61
24431843 2013
30
Management of hemangioma of the liver: surgical therapy or observation? 61
23354918 2013
31
Successful liver resection in a giant hemangioma with intestinal obstruction after embolization. 61
23704832 2013
32
Management of giant liver hemangiomas: an update. 61
23445235 2013
33
Spontaneous rupture of giant liver hemangioma: case report. 61
23539918 2013
34
Airway management in a toddler with a giant hemangioma of the tongue. 61
23429176 2012
35
Recurrent giant hemangiomas of liver: Report of two rare cases with literature review. 61
23494295 2012
36
Resection for progressively growing giant hemangioma of anterior abdominal wall. 61
22808765 2012
37
[The treatment of the sponateneous biloma and choledocholithiasis after the liver resection on the reason of the giant hemangioma]. 61
22810542 2012
38
Pre-operative arterial embolization of symptomatic giant hemangioma of the liver. 61
22691287 2012
39
[Successful anesthetic management for resection of a giant hepatic hemangioma with Kasabach-Merritt syndrome using FloTrac system]. 61
22175175 2011
40
Resection of giant liver hemangioma in a pregnant woman with coagulopathy: Case report and literature review. 61
22905301 2011
41
Surgical Management for Giant liver Hemangiomas Greater Than 20 cm in Size. 61
21814606 2011
42
Robotic right hepatectomy for giant hemangioma in a Jehovah's Witness. 61
20596878 2011
43
Hepatic angiomyolipoma with a giant hemangioma. 61
22041879 2011
44
A symptomatic giant hepatic hemangioma treated with hepatectomy. 61
21389646 2011
45
Management of giant hemangioma of the liver: resection versus observation. 61
20980175 2010
46
Laparoscopic partial splenectomy for giant hemangioma misdiagnosed as splenic cyst: a case report. 61
21180283 2010
47
Giant liver hemangioma resected by trisectorectomy after efficient volume reduction by transcatheter arterial embolization: a case report. 61
20731839 2010
48
Resection of a rapid-growing 40-cm giant liver hemangioma. 61
21161011 2010
49
Solitary giant hemangioma of the humerus. 61
19968232 2009
50
Brachial plexus paralysis due to giant cavernous hemangioma with Kasabach-Merritt syndrome: successful management with interferon alpha. 61
19929246 2009

Variations for Giant Hemangioma

Expression for Giant Hemangioma

Search GEO for disease gene expression data for Giant Hemangioma.

Pathways for Giant Hemangioma

GO Terms for Giant Hemangioma

Cellular components related to Giant Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 SERPINC1 SERPINA3 IFNA2 F3 F2 CGA
2 endoplasmic reticulum lumen GO:0005788 9.5 SERPINC1 F2 AFP
3 extracellular space GO:0005615 9.5 SERPINC1 SERPINA3 IFNA2 F3 F2 CGA
4 blood microparticle GO:0072562 9.43 SERPINC1 SERPINA3 F2
5 collagen-containing extracellular matrix GO:0062023 9.02 SERPINC1 SERPINA3 IFNA2 F3 F2

Biological processes related to Giant Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.43 SERPINC1 F2 AFP
2 acute-phase response GO:0006953 9.32 SERPINA3 F2
3 regulation of blood coagulation GO:0030193 9.16 SERPINC1 F2
4 hemostasis GO:0007599 9.13 SERPINC1 F3 F2
5 blood coagulation GO:0007596 8.92 SERPINC1 IFNA2 F3 F2

Sources for Giant Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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