Drugs for Glaucoma 3, Primary Congenital, a (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 19)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Benzocaine |
Approved, Investigational |
Phase 3 |
|
1994-09-7, 94-09-7 |
2337 |
Synonyms:
(P-(Ethoxycarbonyl)phenylamine
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-Aminobenzoate
4-Aminobenzoate ethyl ester
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Carbethoxyaniline
Acetate, benzocaine
Aethoform
AEZODENT
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthin
Anestezin
Anesthesin
Anesthesine
Anesthone
ANTHISAN PLUS
AR01
AR-01
Baby anbesol
Bensokain
Benzoak
Benzocaina
BENZOCAINE
Benzocaine acetate
Benzocaine formate
Benzocaine hydrobromide
Benzocaine hydrochloride
Benzocaine methanesulfonate
Benzocainum
BURNEZE
CHILDREN'S CHLORASEPTIC
DEQUACAINE
Dermoplast
Diet ayds
Ethoform
Ethyl 4-aminobenzoate
|
Ethyl 4-aminobenzoic acid
Ethyl aminobenzoate
Ethyl aminobenzoic acid
Ethyl P-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethyl p-aminophenylcarboxylic acid
Ethylester kyseliny P-aminobenzoove
Formate, benzocaine
Hurricaine
Hydrobromide, benzocaine
Hydrochloride, benzocaine
Identhesin
Keloform
LANACANE
MEDILAVE
Methanesulfonate, benzocaine
NESTOSYL
Norcain
Norcaine
NSC-41531
NSC-4688
Orabase-b
Ora-jel
ORAJEL
Orthesin
p-(Ethoxycarbonyl)aniline
P-Aminobenzoate
P-Aminobenzoic acid
P-Aminobenzoic acid ethyl ester
Parathesin
Parathesine
p-Carbethoxyaniline
p-Ethoxycarboxylic aniline
Slim mint gum
Solarcaine
Solu H
Topcaine
TYROSOLVEN
TYROZETS
|
|
2 |
|
Tannic acid |
Approved |
Phase 3 |
|
1401-55-4 |
16129878 16129778 |
Synonyms:
Acid, tannic
ácido tánico
Acids, tannic
E181
FEMA NO. 3042
Gallotannic acid
|
Gallotannin
NSC-656273
TANNIC ACID
Tannic acids
Tannins
|
|
3 |
|
Travoprost |
Approved |
Phase 3 |
|
157283-68-6 |
5282226 |
Synonyms:
(((1R)-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-5-heptenoic acid, 1-methylethyl ester
AL-6221
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(a,a,a-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoate
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(a,a,a-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoic acid
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(alpha,alpha,alpha-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoate
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(alpha,alpha,alpha-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoic acid
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoate
|
Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3R)-3-hydroxy-4-[(α,α,α-trifluoro-m-tolyl)oxy]-1-butenyl}cyclopentyl)-5-heptenoic acid
IZBA
Travatan
Travatan Z
TRAVOPROST
Travoprostum
Z, Travatan
|
|
4 |
|
Timolol |
Approved |
Phase 3 |
|
26839-75-8 |
5478 33624 |
Synonyms:
(-)-S-TIMOLOL
(S)-1-(TERT-BUTYLAMINO)-3-[(4-MORPHOLIN-4-YL-1,2,5-THIADIAZOL-3-YL)OXY]PROPAN-2-OL
Apo-Timol
Apo-Timop
Aquanil
BETIM
BETIMOL
BLOCADREN
GLAUCOL
GLAU-OPT
ISTALOL
Novo-Timol
Nu-Timolol
NYO142
NYOGEL
Phoxal-timolol
Proflax
Temserin
Tenopt
|
Timacar
Timacor
Tim-AK
TIMOLOL
TIMOLOL ANHYDROUS
TIMOLOL HEMIHYDRATE
Timolol maleate
Timololo
Timololum
Timololum [INN-Latin]
Timopic
TIMOPTIC
Timoptic in Ocudose
Timoptic OcuDose
Timoptic®
TIMOPTIC-XE
Timoptol
TIOPEX
|
|
5 |
|
Ophthalmic Solutions |
|
Phase 3 |
|
|
|
6 |
|
Pharmaceutical Solutions |
|
Phase 3 |
|
|
|
7 |
|
Neurotransmitter Agents |
|
Phase 3 |
|
|
|
8 |
|
Adrenergic beta-Antagonists |
|
Phase 3 |
|
|
|
9 |
|
Adrenergic Antagonists |
|
Phase 3 |
|
|
|
10 |
|
Adrenergic Agents |
|
Phase 3 |
|
|
|
11 |
|
Anti-Arrhythmia Agents |
|
Phase 3 |
|
|
|
12 |
|
Antihypertensive Agents |
|
Phase 3 |
|
|
|
13 |
|
Mitomycin |
Approved |
|
|
50-07-7 |
5746 |
Synonyms:
7-Amino-9alpha-methoxymitosane
7-Amino-9a-methoxymitosane
7-Amino-9α-methoxymitosane
Ametycine
Mitamycin
Mitocin C
MitocinC
Mitocin-C
Mitomycin
|
Mitomycin C
Mitomycin-C
MITOSOL
MITOZYTREX
MMC
Muamycin
Mutamycin
MYTOZYTREX
NSC-26980
|
|
14 |
|
Hyaluronic acid |
Approved, Vet_approved |
|
|
9004-61-9 |
53477741 |
Synonyms:
(2S,3S,4R,5R,6R)-3-[(2S,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylate
(2S,3S,4R,5R,6R)-3-[(2S,3R,4R,5S,6R)-3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid
(2S,3S,4R,5R,6R)-3-{[(2S,3R,4R,5S,6R)-4,5-dihydroxy-3-[(1-hydroxyethylidene)amino]-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5,6-trihydroxyoxane-2-carboxylate
2-Acetamido-2-deoxy-b-D-gluco-hexopyranosyl-(1->4)-b-D-gluco-hexopyranuronate
2-Acetamido-2-deoxy-b-D-gluco-hexopyranosyl-(1->4)-b-D-gluco-hexopyranuronic acid
2-Acetamido-2-deoxy-beta-D-gluco-hexopyranosyl-(1->4)-beta-D-gluco-hexopyranuronate
|
2-Acetamido-2-deoxy-beta-D-gluco-hexopyranosyl-(1->4)-beta-D-gluco-hexopyranuronic acid
2-Acetamido-2-deoxy-β-D-gluco-hexopyranosyl-(1->4)-β-D-gluco-hexopyranuronate
2-Acetamido-2-deoxy-β-D-gluco-hexopyranosyl-(1->4)-β-D-gluco-hexopyranuronic acid
Hyaluronan
Hyaluronate
WURCS=2.0/2,2,1/[a2122a-1b_1-5][a2122h-1b_1-5_2*ncc/3=o]/1-2/a4-b1
|
|
15 |
|
Anti-Bacterial Agents |
|
|
|
|
|
16 |
|
Alkylating Agents |
|
|
|
|
|
17 |
|
Antibiotics, Antitubercular |
|
|
|
|
|
18 |
|
Endothelial Growth Factors |
|
|
|
|
|
19 |
|
Mitogens |
|
|
|
|
|
Interventional clinical trials:
(show all 24)
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Comparison of the Ahmed Glaucoma Valve FP7 and FP8 in Pediatric Glaucoma: a Randomized Clinical Trial. |
Unknown status |
NCT01494974 |
Phase 4 |
|
2 |
A 3 Month, Multicenter, Double-Masked Safety and Efficacy Study of Travoprost Ophthalmic Solution, 0.004% Compared to Timolol (0.5% or 0.25%) in Pediatric Glaucoma Patients |
Completed |
NCT01652664 |
Phase 3 |
Travoprost 0.004% PQ ophthalmic solution;Timolol, 0.5% or 0.25% ophthalmic solution;Travoprost Vehicle |
3 |
Masked, Randomized, Single-site, Crossover Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101 Dosed for 14 Days in Adult Subjects With Sturge-Weber Syndrome (SWS)-Related Glaucoma Due to Elevated Episcleral Venous Pressure (EVP) |
Completed |
NCT04947124 |
Phase 2 |
QLS-101ophthalmic solution 1%;QLS-101ophthalmic solution 2% |
4 |
Comparative Evaluation of Combined Trabeculotomy-trabeculectomy Versus Combined Trabeculotomy-trabeculectomy With Subconjunctival Implantation of Collagen Matrix Implant for Primary Congenital Glaucoma. |
Unknown status |
NCT02121171 |
Phase 1 |
|
5 |
Comparison Between The Outcome of Deep Sclerectomy and Traditional Trabeculotomy and Trabeculectomy Surgeries in Congenital Glaucoma |
Unknown status |
NCT01460017 |
Phase 1 |
|
6 |
Histopathological Examination of Iris Tissue in Primary Congenital Glaucoma |
Unknown status |
NCT04079725 |
|
|
7 |
Genetic Testing in Primary Congenital Glaucoma Patients |
Unknown status |
NCT01136460 |
|
|
8 |
Study of Gene, Inheritance Pattern and Genotype - Phenotype Correlations in South Korean Patients With Primary Congenital Glaucoma |
Unknown status |
NCT01020721 |
|
|
9 |
Histopathological Examination of Iris Tissue in Buphthalmos |
Completed |
NCT04011878 |
|
|
10 |
Microcatheter Assisted Circumferential Trabeculotomy in Congenital Glaucoma |
Completed |
NCT04116450 |
|
|
11 |
Surgical Outcomes of Visco-Circumferential-Suture-Trabeculotomy in Primary Congenital Glaucoma: A 3-year Randomized Controlled Study |
Completed |
NCT04683289 |
|
|
12 |
Randomized Controlled Study to Evaluate Safety and Efficacy of Ologen® Collagen Matrix in Patients With Primary Congenital Glaucoma Undergoing Trabeculectomy |
Completed |
NCT03541551 |
|
|
13 |
A Prospective Open-label, Multicenter Clinical Investigation to Assess the Safety and Performance of ARGOS-IO System in Patients Undergoing Implantation of a Boston Keratoprosthesis (BKPro) |
Completed |
NCT02945176 |
|
|
14 |
Endoscopic Goniotomy for Infantile Glaucoma |
Completed |
NCT00338533 |
|
|
15 |
Long Term Evaluation of Primary Congenital Glaucoma Management In Sohag University Hospital |
Recruiting |
NCT04949555 |
|
|
16 |
Determination of the Sensitivity and Specificity of a Smartphone Application to Detect Retinoblastoma |
Active, not recruiting |
NCT03016156 |
|
|
17 |
Prospective Study of the Diagnostic and Therapeutic Management of Congenital Glaucoma in France |
Active, not recruiting |
NCT03077789 |
|
|
18 |
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma: Long-term Results and Success Predictors Analysed From a Large-scale Retrospective and Prospective Glaucoma Register |
Enrolling by invitation |
NCT04381611 |
|
|
19 |
Long Term Surgical Outcomes of Viscotrabeculotomy in Pediatric Glaucoma Following Cataract Surgery |
Not yet recruiting |
NCT05011747 |
|
|
20 |
Surgery for Primary Congenital Glaucoma in Neonates:Randomized Controlled Study. |
Not yet recruiting |
NCT04709497 |
|
|
21 |
Evaluation of Primary Congenital Glaucoma Management at Asyut University Hospital |
Not yet recruiting |
NCT05205122 |
|
|
22 |
Kahook Dual Blade Ab-interno Trabeculotomy Versus ab Externo Viscotrabeculotomy in Primary Congenital Glaucoma |
Not yet recruiting |
NCT05115708 |
|
|
23 |
Estimation of Vascular Endothelial Growth Factor (VEGF) in Iris Tissue in Primary Congenital Glaucoma |
Not yet recruiting |
NCT05484050 |
|
|
24 |
Comparison of Surgical Treatment Options for Primary Congenital and Developmental Glaucomas |
Not yet recruiting |
NCT04647929 |
|
|
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