MCID: GLB012
MIFTS: 13

Glioblastoma Proneural Subtype

Categories: Bone diseases, Cancer diseases, Neuronal diseases

Aliases & Classifications for Glioblastoma Proneural Subtype

MalaCards integrated aliases for Glioblastoma Proneural Subtype:

Name: Glioblastoma Proneural Subtype 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050804

Summaries for Glioblastoma Proneural Subtype

Disease Ontology : 12 A glioblastoma multiforme that is characterized by IDH1 and p53 mutations and Platelet Derived Growth Factor A amplification.

MalaCards based summary : Glioblastoma Proneural Subtype is related to glioblastoma multiforme. An important gene associated with Glioblastoma Proneural Subtype is NUBP2 (Nucleotide Binding Protein 2), and among its related pathways/superpathways are Cell cycle and Cyclins and Cell Cycle Regulation. Affiliated tissues include bone, and related phenotype is endocrine/exocrine gland.

Related Diseases for Glioblastoma Proneural Subtype

Diseases related to Glioblastoma Proneural Subtype via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 glioblastoma multiforme 10.2

Symptoms & Phenotypes for Glioblastoma Proneural Subtype

MGI Mouse Phenotypes related to Glioblastoma Proneural Subtype:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 8.92 ALDH1A3 CCNB2 CDKN2D USP1

Drugs & Therapeutics for Glioblastoma Proneural Subtype

Search Clinical Trials , NIH Clinical Center for Glioblastoma Proneural Subtype

Genetic Tests for Glioblastoma Proneural Subtype

Anatomical Context for Glioblastoma Proneural Subtype

MalaCards organs/tissues related to Glioblastoma Proneural Subtype:

40
Bone

Publications for Glioblastoma Proneural Subtype

Articles related to Glioblastoma Proneural Subtype:

# Title Authors PMID Year
1
CDK4/6 inhibition is more active against the glioblastoma proneural subtype. 61
28903422 2017

Variations for Glioblastoma Proneural Subtype

Expression for Glioblastoma Proneural Subtype

Search GEO for disease gene expression data for Glioblastoma Proneural Subtype.

Pathways for Glioblastoma Proneural Subtype

Pathways related to Glioblastoma Proneural Subtype according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.52 CDKN2D CCNB2
2
Show member pathways
11.31 CDKN2D CCNB2
3
Show member pathways
10.76 CDKN2D CCNB2

GO Terms for Glioblastoma Proneural Subtype

Biological processes related to Glioblastoma Proneural Subtype according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 8.96 CDKN2D CCNB2
2 response to UV GO:0009411 8.62 USP1 CDKN2D

Sources for Glioblastoma Proneural Subtype

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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