GDACCF
MCID: GLB021
MIFTS: 38

Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies (GDACCF)

Categories: Genetic diseases

Aliases & Classifications for Global Developmental Delay, Absent or Hypoplastic Corpus...

MalaCards integrated aliases for Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies:

Name: Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies 56 73 36 6
Gdaccf 56 73
Developmental Disabilities 71

Characteristics:

OMIM:

56
Inheritance:
autosomal dominant

Miscellaneous:
variable phenotype
de novo mutation
four unrelated patients have been reported (last curated december 2016)


HPO:

31
global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies:
Inheritance autosomal dominant inheritance


Classifications:



Summaries for Global Developmental Delay, Absent or Hypoplastic Corpus...

OMIM : 56 GDACCF is an intellectual disability syndrome apparent soon after birth with neonatal hypotonia, poor feeding, and respiratory insufficiency followed by delayed psychomotor development and intellectual disability with poor speech. Brain imaging shows aplasia or hypoplasia of the corpus callosum. Affected individuals have variable dysmorphic facial features, and some may have dysplastic, cystic kidneys or mild cardiac defects (summary by Stevens et al., 2016). (617260)

MalaCards based summary : Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies, is also known as gdaccf, and has symptoms including symptoms An important gene associated with Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies is ZNF148 (Zinc Finger Protein 148). The drugs Dopamine and Acetylcholine have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and kidney, and related phenotypes are growth hormone deficiency and coarse facial features

KEGG : 36 Global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies (GDACCF) is a syndromic intellectual disability with corpus callosum anomalies and short stature as shared features. It may be accompanied by microcephaly, feeding problems, and variable facial features. Truncating de novo mutations in the Kruppel-type zinc-finger gene ZNF148 have been reported in patients.

UniProtKB/Swiss-Prot : 73 Global developmental delay, absent or hypoplastic corpus callosum, and dysmorphic facies: An autosomal dominant syndrome characterized by underdevelopment of the corpus callosum, mild to moderate developmental delay and intellectual disability, variable microcephaly or mild macrocephaly, short stature, feeding problems, facial dysmorphisms, and cardiac and renal malformations.

Related Diseases for Global Developmental Delay, Absent or Hypoplastic Corpus...

Symptoms & Phenotypes for Global Developmental Delay, Absent or Hypoplastic Corpus...

Human phenotypes related to Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies:

31 (showing 35, show less)
# Description HPO Frequency HPO Source Accession
1 growth hormone deficiency 31 occasional (7.5%) HP:0000824
2 coarse facial features 31 HP:0000280
3 intellectual disability 31 HP:0001249
4 global developmental delay 31 HP:0001263
5 pes planus 31 HP:0001763
6 microcephaly 31 HP:0000252
7 smooth philtrum 31 HP:0000319
8 short stature 31 HP:0004322
9 feeding difficulties 31 HP:0011968
10 frontal bossing 31 HP:0002007
11 epicanthus 31 HP:0000286
12 coarctation of aorta 31 HP:0001680
13 hypoplastic left heart 31 HP:0004383
14 respiratory insufficiency 31 HP:0002093
15 talipes equinovarus 31 HP:0001762
16 wide mouth 31 HP:0000154
17 downslanted palpebral fissures 31 HP:0000494
18 upslanted palpebral fissure 31 HP:0000582
19 patent ductus arteriosus 31 HP:0001643
20 ventriculomegaly 31 HP:0002119
21 telecanthus 31 HP:0000506
22 pointed chin 31 HP:0000307
23 agenesis of corpus callosum 31 HP:0001274
24 triangular face 31 HP:0000325
25 hypoplasia of the corpus callosum 31 HP:0002079
26 mitral stenosis 31 HP:0001718
27 renal cyst 31 HP:0000107
28 generalized hypotonia 31 HP:0001290
29 short palpebral fissure 31 HP:0012745
30 abnormality of the pinna 31 HP:0000377
31 renal dysplasia 31 HP:0000110
32 hypermetropia 31 HP:0000540
33 poor speech 31 HP:0002465
34 low hanging columella 31 HP:0009765
35 delayed ability to walk 31 HP:0031936

Symptoms via clinical synopsis from OMIM:

56
Neurologic Central Nervous System:
intellectual disability
poor speech
enlarged ventricles
absent corpus callosum
delayed psychomotor development
more
Growth Height:
short stature

Cardiovascular Heart:
patent ductus arteriosus
aortic coarctation
hypoplastic left heart syndrome
mitral valve stenosis
cardiac defects (in 2 of 4 patients)

Muscle Soft Tissue:
hypotonia

Abdomen Gastrointestinal:
poor feeding

Head And Neck Ears:
abnormally shaped ears

Respiratory:
respiratory insufficiency, neonatal

Endocrine Features:
growth hormone deficiency (1 patient)

Head And Neck Face:
smooth philtrum
frontal bossing
pointed chin
triangular face
coarse face

Head And Neck Mouth:
wide mouth

Head And Neck Eyes:
telecanthus
downslanting palpebral fissures
epicanthal folds
hyperopia
short palpebral fissures
more
Skeletal Feet:
flat feet
club feet

Head And Neck Nose:
prominent columella

Growth Other:
poor overall growth

Head And Neck Head:
microcephaly (in 1 of 4 patients)

Genitourinary Kidneys:
cystic kidneys (in 2 of 4 patients)
dysplastic kidneys (in 2 of 4 patients)

Clinical features from OMIM:

617260

UMLS symptoms related to Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies:


symptoms

Drugs & Therapeutics for Global Developmental Delay, Absent or Hypoplastic Corpus...

Drugs for Global Developmental Delay, Absent or Hypoplastic Corpus Callosum, and Dysmorphic Facies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 140, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
2
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
3
Baclofen Approved Phase 4 1134-47-0 2284
4
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
5
Guanfacine Approved, Investigational Phase 4 29110-47-2 3519
6
Valproic acid Approved, Investigational Phase 4 99-66-1 3121
7 Antibodies Phase 4
8 Rho(D) Immune Globulin Phase 4
9 Immunoglobulins, Intravenous Phase 4
10 gamma-Globulins Phase 4
11 Immunologic Factors Phase 4
12 Immunoglobulins Phase 4
13 Dopamine Agents Phase 4
14 Neurotransmitter Agents Phase 4
15 abobotulinumtoxinA Phase 4
16 GABA Agonists Phase 4
17 Botulinum Toxins Phase 4
18 Botulinum Toxins, Type A Phase 4
19 Cholinergic Agents Phase 4
20 Adrenergic alpha-Agonists Phase 4
21 Adrenergic Agonists Phase 4
22 Central Nervous System Stimulants Phase 4
23 Anticonvulsants Phase 4
24
Risperidone Approved, Investigational Phase 3 106266-06-2 5073
25
Cycloserine Approved Phase 3 68-41-7 401 6234
26
Histamine Approved, Investigational Phase 3 51-45-6 774
27
Mirtazapine Approved Phase 3 85650-52-8, 61337-67-5 4205
28
Aripiprazole Approved, Investigational Phase 3 129722-12-9 60795
29
Sodium citrate Approved, Investigational Phase 3 68-04-2
30
Caffeine Approved Phase 3 58-08-2 2519
31
Olanzapine Approved, Investigational Phase 3 132539-06-1 4585
32
Clozapine Approved Phase 3 5786-21-0 2818
33
Haloperidol Approved Phase 3 52-86-8 3559
34
Oxytocin Approved, Vet_approved Phase 3 50-56-6 53477758 439302
35
carbamide peroxide Approved Phase 2, Phase 3 124-43-6
36
Citric acid Approved, Nutraceutical, Vet_approved Phase 3 77-92-9 311
37
Melatonin Approved, Nutraceutical, Vet_approved Phase 3 73-31-4 896
38 Dopamine Antagonists Phase 3
39 Psychotropic Drugs Phase 3
40 Antipsychotic Agents Phase 3
41 Anti-Infective Agents Phase 3
42 Antitubercular Agents Phase 3
43 Anti-Bacterial Agents Phase 3
44 Antibiotics, Antitubercular Phase 3
45 Antimetabolites Phase 3
46 Adrenergic alpha-Antagonists Phase 3
47 Antidepressive Agents Phase 3
48 Histamine Antagonists Phase 3
49 Histamine H1 Antagonists Phase 3
50
Histamine Phosphate Phase 3 51-74-1 65513
51 Anti-Anxiety Agents Phase 3
52 Serotonin 5-HT3 Receptor Antagonists Phase 3
53 Gastrointestinal Agents Phase 3
54 Protective Agents Phase 3
55 Dopamine agonists Phase 3
56 Serotonin Receptor Agonists Phase 3
57 Serotonin 5-HT1 Receptor Agonists Phase 3
58 Antioxidants Phase 3
59 Citrate Phase 3
60 Phosphodiesterase Inhibitors Phase 3
61 Caffeine citrate Phase 3
62 Serotonin Uptake Inhibitors Phase 3
63 Antiemetics Phase 3
64 Haloperidol decanoate Phase 3
65
Serotonin Investigational, Nutraceutical Phase 3 50-67-9 5202
66
Naltrexone Approved, Investigational, Vet_approved Phase 1, Phase 2 16590-41-3 5360515
67
Ethanol Approved Phase 1, Phase 2 64-17-5 702
68
Acetylcysteine Approved, Investigational Phase 2 616-91-1 12035
69
Riluzole Approved, Investigational Phase 2 1744-22-5 5070
70
Propranolol Approved, Investigational Phase 2 525-66-6 4946
71
Memantine Approved, Investigational Phase 2 19982-08-2 4054
72
tannic acid Approved Phase 2 1401-55-4
73
Benzocaine Approved, Investigational Phase 2 94-09-7, 1994-09-7 2337
74
Glutamic acid Approved, Nutraceutical Phase 2 56-86-0 33032
75
Sulforaphane Investigational Phase 2 142825-10-3, 4478-93-7 5350
76 Narcotics Phase 1, Phase 2
77 Narcotic Antagonists Phase 1, Phase 2
78 Sulforafan Phase 2
79 Antidotes Phase 2
80 Respiratory System Agents Phase 2
81 Antiviral Agents Phase 2
82 Expectorants Phase 2
83 N-monoacetylcystine Phase 2
84 Neuroprotective Agents Phase 2
85
Lurasidone hydrochloride Phase 2 367514-87-2 213046
86 Antihypertensive Agents Phase 2
87 Adrenergic Agents Phase 2
88 Adrenergic Antagonists Phase 2
89 Adrenergic beta-Antagonists Phase 2
90 Vasodilator Agents Phase 2
91 Anti-Arrhythmia Agents Phase 2
92 Excitatory Amino Acid Antagonists Phase 2
93 Antiparkinson Agents Phase 2
94
Mecamylamine Approved, Investigational Phase 1 60-40-2 4032
95
Flumazenil Approved Phase 1 78755-81-4 3373
96
gamma-Aminobutyric acid Approved, Investigational Phase 1 56-12-2 119
97
Zinc Approved, Investigational Phase 1 7440-66-6 32051
98
Copper Approved, Investigational Phase 1 7440-50-8 27099
99
Vitamin C Approved, Nutraceutical Phase 1 50-81-7 5785 54670067
100 Cholinergic Antagonists Phase 1
101 GABA Modulators Phase 1
102 Radiopharmaceuticals Phase 1
103 Micronutrients Phase 1
104 Trace Elements Phase 1
105 Vitamins Phase 1
106 Nutrients Phase 1
107 Liver Extracts Phase 1
108 Copper Supplement Phase 1
109
Calcium carbonate Approved, Investigational 471-34-1
110
Zonisamide Approved, Investigational 68291-97-4 5734
111
leucovorin Approved 58-05-9 6006 143
112
Topiramate Approved 97240-79-4 5284627
113
Verapamil Approved 52-53-9 2520
114
Nitric Oxide Approved 10102-43-9 145068
115
Citalopram Approved 59729-33-8 2771
116
Doxycycline Approved, Investigational, Vet_approved 564-25-0 54671203
117
Hydrocortisone Approved, Vet_approved 50-23-7 5754
118
Hydrocortisone acetate Approved, Vet_approved 50-03-3
119
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
120
Folic acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
121
Vitamin A Approved, Nutraceutical, Vet_approved 22737-96-8, 68-26-8, 11103-57-4 9904001 445354
122 Contraceptive Agents
123 Vitamin B Complex
124 Folate
125 Vitamin B9
126 Anesthetics
127 Hypnotics and Sedatives
128 Hypoglycemic Agents
129 Hormones
130 Calcium, Dietary
131 calcium channel blockers
132 Opiate Alkaloids
133 Retinol palmitate
134 retinol
135 Hematinics
136 Hydrocortisone 17-butyrate 21-propionate
137 Anti-Inflammatory Agents
138 Hydrocortisone hemisuccinate
139 Epoetin alfa 113427-24-0
140
Calcium Nutraceutical 7440-70-2 271

Interventional clinical trials:

(showing 259, show less)
# Name Status NCT ID Phase Drugs
1 A Phase IV, Single-site, Open-Label Study to Evaluate the Efficacy of High-Dose Gammaplex in Children on the Autism Spectrum Unknown status NCT02199925 Phase 4 Gammaplex 5%
2 Vanderbilt University Spasticity Management Program Evaluation Plan Completed NCT00179114 Phase 4 Botulinum Toxin Type A;Intrathecal baclofen administered by the Medtronic SyncroMed(TM) pump (ITB)
3 Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder Completed NCT01238575 Phase 4 extended-release guanfacine
4 Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population Completed NCT00207935 Phase 4
5 Methylphenidate Study in Young Children With Developmental Disorders Completed NCT00517504 Phase 4 Methylphenidate
6 Group Psychoeducational Program for Mothers of Preschool Children With High Functional Pervasive Developmental Disorders: a Randomized Controlled Trial Unknown status NCT01243905 Phase 2, Phase 3
7 A Randomized, Placebo-Controlled Trial of D-Cycloserine for the Enhancement of Social Skills Training in Pervasive Developmental Disorders Completed NCT01086475 Phase 3 D-cycloserine;Placebo
8 Mirtazapine Treatment of Anxiety in Children and Adolescents With Pervasive Developmental Disorders Completed NCT01302964 Phase 3 Placebo;Mirtazapine
9 Efficacy And Safety Of Risperidone In The Treatment Of Children With Autistic Disorder And Other Pervasive Developmental Disorders: A Canadian, Multicenter, Double-Blind, Placebo-Controlled Study Completed NCT00261508 Phase 3 risperidone
10 Pharmacotherapy of Pervasive Developmental Disorders Completed NCT00870727 Phase 3 Aripiprazole oral product;Placebo oral capsule
11 Supporting the Well Being of Families of Young Children With Autism Spectrum Completed NCT01021384 Phase 3
12 2/3 Treatment of Anxiety in Autism Spectrum Disorder Completed NCT02028247 Phase 3
13 Efficacy and Safety of Methylxanthines in Very Low Birthweight Infants Completed NCT00182312 Phase 3 Caffeine citrate injection
14 Severe Aberrant Behavior Among Persons With Mental Retardation. Project III: Behavioral Selectivity of Atypical Neuroleptic Drugs: Effects on Cognitive and Social Behaviors Completed NCT00065273 Phase 3 risperidone;clozapine;olanzapine
15 Multicenter Double-blind Placebo-Controlled Randomized Clinical Trial of Efficacy and Safety of Tenoten for Children in the Treatment of Specific Developmental Disorders of Scholastic Skills in Children Completed NCT03159104 Phase 3 Tenoten for children;Placebo
16 Effects of Risperidone on Cognitive-Motor Performance and Motor Movements in Chronically Medicated Children Completed NCT00399698 Phase 3 Risperdal
17 A Randomized Controlled Trial Pilot Project to Evaluate the Efficacy of Melatonin in Children With Insomnia, Intractable Epilepsy and Neurodevelopmental Disabilities Completed NCT01161108 Phase 3 Fast Release Melatonin (FR MLT);Fast Release Placebo;Timed Release Melatonin (TR MLT);Timed Release Placebo
18 A Pilot Study of Oxytocin for the Treatment of Social Impairment in Individuals With High Functioning Autism Spectrum Disorder Active, not recruiting NCT02985749 Phase 3 Intranasal Oxytocin
19 N-Carbamylglutamate (Carbaglu) In The Treatment Of Hyperammonemia Active, not recruiting NCT00843921 Phase 2, Phase 3 N-carbamylglutamate
20 Randomized Double-Blind Trial of Low-Dose Naltrexone for Children With PDD Unknown status NCT00318162 Phase 1, Phase 2 low dose naltrexone
21 A Randomized, Placebo-Controlled Phase II Trial Evaluating Safety and Efficacy of Oral Human Immunoglobulin in the Treatment of Gastrointestinal Dysfunction Associated With Autistic Disorder in Pediatric Patients From 2 to 18 Years of Age Unknown status NCT00110708 Phase 2 Oralgam (human immunoglobulin)
22 Effect of Endermotherapy on Passive Ankle Range of Motion in Children With Developmental Disabilities Completed NCT01207570 Phase 2
23 Pharmacogenetics of Risperidone in Children With Pervasive Developmental Disorder (PDD) Completed NCT00166595 Phase 1, Phase 2 Risperidone
24 A Phase II, Randomized, Double-blind, Placebo-controlled Study of Myrosinase-enriched Glucoraphanin, a Sulforaphane Precursor System, in Autism Spectrum Disorder Completed NCT02909959 Phase 2 Sulforaphane;Placebo
25 An Open-Label Study of Aripiprazole in Children and Adolescents With Autistic Disorder Completed NCT00198055 Phase 2 aripiprazole
26 Effects of Intensity of Early Communication Intervention Completed NCT00723151 Phase 2
27 Therapeutic Issues for Autism Spectrum Disorders: a Clinical Trial Completed NCT03887754 Phase 2 Risperidone;Non specific Multivitamin
28 A Pilot Study of Oral N-Acetylcysteine in Children With Autism Spectrum Disorders Completed NCT00453180 Phase 2 N-acetylcysteine;Placebo
29 An Investigation of the Efficacy in Childhood Obsessive-Compulsive Disorder of Riluzole: An Antiglutamatergic Agent Completed NCT00251303 Phase 2 Riluzole;Placebo
30 An Open-Label Study of the Safety and Tolerability of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) Completed NCT01592786 Phase 2 Memantine Hydrochloride (HCl)
31 A Double-Blind, Placebo-Controlled, Randomized Withdrawal Study of the Safety and Efficacy of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) Previously Treated With Memantine Completed NCT01592747 Phase 2 Memantine Hydrochloride (HCl);Memantine Hydrochloride (HCl);Placebo capsules
32 An Open-Label Pilot Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents Completed NCT01731119 Phase 2 Latuda©
33 CBT for Comorbid Anxiety Disorders in Children With Autism, Asperger Syndrome, or PDD-NOS Completed NCT00280670 Phase 2
34 CBT for Anxiety Disorders in Autism: Adapting Treatment for Adolescents Completed NCT01177969 Phase 1, Phase 2
35 Cholesterol in Autism Spectrum Disorder (ASD): Characterization and Treatment Completed NCT00965068 Phase 1, Phase 2
36 A Prospective Open-Label Trial of Aripiprazole Monotherapy in the Autism Spectrum Disorders (ASD) Completed NCT00308074 Phase 2 Aripiprazole
37 A Pilot/Feasibility Study of the Use of High Dose Propranolol to Treat Severe and Chronic Challenging Behaviors in Adolescents and Adults With Autism Spectrum Disorders Recruiting NCT04047355 Phase 2 Propranolol
38 An Open-Label Extension Study of the Safety and Tolerability of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) Terminated NCT01592773 Phase 2 Memantine Hydrochloride (HCl)
39 An Investigation of the Efficacy of Mercury Chelation as a Treatment for Autism Spectrum Disorder Withdrawn NCT00376194 Phase 2 DMSA
40 An RCT of a Low-Intensity Intervention to Reduce Delay Unknown status NCT00110292 Phase 1
41 Neuronal Nicotinic Receptor Modulation in the Treatment of Autism: A Pilot Trial of Mecamylamine Completed NCT00773812 Phase 1 mecamylamine;placebo
42 Risperidone Pharmacokinetics in Children With Pervasive Developmental Disorder Completed NCT00147394 Phase 1 Risperidone
43 The Connection Between Sensory Deprivation and Social Withdrawal in Clients of a Long Term Care Facility Living With Alzheimer's Disease and the Effects of a Snoezelen Program. Completed NCT00548951 Phase 1
44 A Cognitive-Behavioral Intervention for Children With Autism Spectrum Disorders Completed NCT00926471 Phase 1
45 A Phase One Treatment Trial of the Circadian Sleep Disturbance in Smith-Magenis Syndrome (SMS) Completed NCT00506259 Phase 1 dTR Melatonin (NIH CC PDS);Melatonin CR
46 Cross-Species Multi-Modal Neuroimaging to Investigate GABA Physiology in Fragile X Syndrome Recruiting NCT04308954 Phase 1 [18F]flumazenil
47 Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism Terminated NCT00325572 Phase 1 oral zinc and vitamin C supplements
48 A Longitudinal Study of Function and Participation in Life Activities of Patients With Developmental Disabilities Unknown status NCT02930603
49 The System of Relationships Between Parents and Their Toddlers, With Eating Disorders and Sensory Processing Disorders Within Meal and Play Situations Unknown status NCT00531648
50 The Investigation of Children With Developmental Delay and Children's Rehabilitation Common Case: A Longitudinal Study Unknown status NCT02686931
51 The Relationship of Body Function, Participation and Quality of Life in Patients With Burn: A Longitudinal Study Unknown status NCT02950675
52 Prevelance of Molar Incisors Hypomineralization Among a Group of Egyptian Children Unknown status NCT03067064
53 Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities Unknown status NCT00716235
54 Development of a New Diagnosis and Intervention Method for Developmental Disorders Unknown status NCT01166152
55 S100B as a Marker of Brain Injury of Preterm Infants Unknown status NCT02082535
56 Assessment of Factors Which Predict Improvement in Children With PDD After a Year of Integrative Therapy Unknown status NCT00531830
57 Effectiveness of Nurse Home Contraceptive Dispensing Unknown status NCT00065078
58 Spreken Verfijnen in de Kleuterklas: De Ontwikkeling Van Een Spraakdidactiek Als Uitbreiding op de Gangbare Taaldidactiek in Het Kleuteronderwijs Unknown status NCT02313025
59 Habituation's Mechanisms in Preterm and Term Infants. Behavioral Evaluation: APIB (Assessment of Preterm Infant's Behavior). Assessment of the Cortical and Vegetative Responses Unknown status NCT02496104
60 Effects of Hyperbaric Oxygenation Therapy on Adaptive, Aberrant and Stereotyped Behaviors in Children With Autism Unknown status NCT00404846
61 Validity and Reliability of Turkish Version of Turkish Version of The Measure of Processes of Care (MPOC 56-20- SP) Unknown status NCT03508583
62 Brain Lesions in Relation to Motor Profiles of Children With Cerebral Visual Impairment. Unknown status NCT02480452
63 Phase 1 Study of a Digital/Internet/Mobile System for Collecting, Charting and Communicating About the Behaviors of Children on the Autism Spectrum Unknown status NCT01005953
64 Are IQs Low in Offspring of Euthyroid Women With Low T4? Unknown status NCT00147433
65 Development of a Resiliency Training Program for Parents of Children With Autism Spectrum Disorder Unknown status NCT02995408
66 Innovative Game-Based Rehabilitation Platform for Children With Motor and Cognitive Impairments Due to Neuro-developmental Disorders and Acquired Brain Injuries Unknown status NCT02728375
67 Enteral Formula Tolerance In Pediatric Patients With Developmental Disabilities Completed NCT01469117
68 Investigation of "Family-centered" Pediatric Rehabilitation Services Received by Children With Developmental Disabilities Completed NCT02057809
69 Open Label Study of Zonisamide in the Treatment of Epilepsy in Patients With Mental Retardation / Developmental Disabilities Completed NCT00298818
70 Evaluation of the Efficacy of Hippotherapy for Children With Developmental Disorders Completed NCT00717392
71 Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities Completed NCT03218462
72 Developing an Interdisciplinary Pharmacogenomic Treatment Approach to Reduce Medication Burden and Improve Subject Outcomes Completed NCT01274065
73 A Randomized Efficacy Trial of the Kids in Transition to School (KITS) Program for Children With Developmental Disabilities and Behavioral Problems Completed NCT01593189
74 Effectiveness of the Just Right Challenge Food Club for Decreasing Food Selectivity and Increasing Mealtime Quality Completed NCT03756844
75 The Experiences of Parents Learning Physiotherapy Techniques for Their Child Completed NCT02090946
76 Tube Feeding Tolerance After Switch to Peptide Based Formula in Children With Developmental Delay: A Retrospective Assessment Completed NCT02912065
77 Weight Loss and Maintenance for Individuals With Intellectual Developmental Disabilities (IDD) Completed NCT01724905
78 Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome—Correlation With Cerebral Non-invasive Infrared Spectroscopy (NIRS) Completed NCT00399555
79 A Randomized Controlled Trial of DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities Completed NCT01794013
80 Effectiveness of an Oral Health Education Program for Caregivers of Children With Developmental Disabilities: A Cluster Randomized Trial Completed NCT03157596
81 A Multiple Baseline Design Study to Investigate the Effectiveness of OT-SI Using an Intensive Intervention Model Completed NCT03355417
82 Evaluating a Brief Intensive Intervention for Individuals With Fragile X Syndrome Completed NCT01204151
83 The Family Networks Project Study One: Supporting Family Confidence, Competence, and Community Connections Completed NCT01424943
84 Let's Talk About Pain: A Randomized Controlled Trial Testing the Effectiveness of a Pain Assessment and Management Training Program for Respite Workers Supporting Children With Intellectual and Developmental Disabilities Completed NCT03421795
85 Resolution of Primary Immune Defect in 22q11.2 Deletion Syndrome Completed NCT02460328
86 Use of a Family Navigator in Families With Children Newly Diagnosed With Autism Spectrum Disorder Completed NCT01340092
87 Crowd Funding and Social Networks as a Novel Mechanism to Promote Sustainable Physical Growth and Positive Psychosocial and Neurodevelopmental Outcomes in Severely Stunted Guatemalan Children Completed NCT02509936
88 Dosage Effects of Folic Acid on Blood Folates of Honduran Women Completed NCT00207532 folic acid
89 Efficacy of a Health Intervention for People With Intellectual Disabilities Completed NCT00597948
90 Prevalence of Spasticity in Adults With Mental Retardation Residing in a Community Setting Completed NCT00282191
91 Evaluation of Project TEAM (Teens Making Environmental and Activity Modifications) - Effectiveness, Social Validity and Feasibility Completed NCT02714868
92 Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes Completed NCT00342667
93 The Influence of Motor Imagery in Fine Motor Skills of Individuals With Disabilities Completed NCT02725450
94 Investigation of Postural Control, Grip Strength and Body Posture in Children With Intellectual Disability and Dyslexia Completed NCT04250701
95 Recording Facial and Vocal Emotional Productions in Children With Autism as Part of the JEMImE Project Completed NCT03177590
96 Bone Mass Accrual in Children With Autism Spectrum Disorder Completed NCT03162445
97 Extracellular Signal-Related Kinase Biomarker Development in Autism Completed NCT01850459
98 MR Scanning of Very Young Children With Severe Developmental Disorders (Autistic Spectrum Disorders and/or Mental Retardation and/or Language Disorders) Completed NCT00156221
99 Facilitating Employment for Youth With Autism: A Replication Study of an Internship Model to Identify Evidence Based Practices Completed NCT03560453
100 Reliability of Hammersmith Examination in Prediction of Neurological Outcomes In Preterm Infants - Observational Study (REHAPENO) Completed NCT03580252
101 Risperidone and Behavioral Therapy in Treatment of Children and Adolescents With Autistic Disorder Completed NCT00080145 Risperidone
102 Safety and Efficacy of Allogeneic Umbilical Cord Blood Therapy for Children With Global Developmental Delay Completed NCT01601158
103 Growth and Body Composition in Children With Disabilities and Typically Developing Children Completed NCT03653754
104 A Study to Determine if CHICA Can Improve Developmental Screening Completed NCT01351077
105 Colorado Early Intervention Outcomes Research Using Innovative Patient-Reported Outcome (PRO) Measures Completed NCT03904797
106 Build Your Parenting Toolkit: Guiding Children to Become Flexible Thinkers. SCRC/LIFE Program Pilot Project Completed NCT02803801
107 The Effectiveness of Collaborative Consultation for Participation Among Students With Moderate Intellectual Disability (Co-PID) Completed NCT02797639
108 Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety Completed NCT01919970
109 Developing and Testing a New Model for Telephone-based Early Childhood Developmental Screening and Care Coordination in Vulnerable Populations Completed NCT02495025
110 Feasibility Study for Pediatric NeuroDevelopmental Assessment Study (PANDAS) Completed NCT00754897
111 Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID) Completed NCT00579267
112 Psychomotor Therapy Effects Adaptive Behavior and Motor Proficiency of Adults With Intellectual Disability Completed NCT02746614
113 Environmental Factors in the Etiology of Autism Completed NCT00106652
114 Effect of Improving Caregiving on Early Mental Health Completed NCT00057291
115 Does Mindfulness Training Enhance Early Evidence-based Parent-coaching Interventions for Autism Spectrum Disorder?: A Randomized Controlled Trial Completed NCT03889821
116 Validation of the French Adaptation of the Scale Aiding in the Diagnosis of the Autism Spectrum Disorders : Scale of Asperger Syndrome Diagnosis Completed NCT02826148
117 Evaluation of Family Networks (FaNs) for Children With Developmental Disorders and Delays Program: A Cluster Randomized Control Trial Completed NCT02792894
118 Evaluation of Resident Surveillance of Pediatric Patient Developmental Status at the Two Month Preventive Care Visit Completed NCT00465361
119 Parent Supports Intervention Project for Parents of Adults With Developmental Disabilities Completed NCT01981070
120 Project for Cognitive Advancement in Infants With Neuromotor DisOrders:The CAN-DO Project Completed NCT02673658
121 Use of an Educational Story to Prepare Children With Developmental Disabilities for Overnight Polysomnography Completed NCT02132273
122 Engaging Children With Mental Health and Developmental Disabilities and Their Parents to Adopt a Healthy Lifestyle: Piloting the Game Squad Home Exergaming & Virtual Health Coaching Intervention Completed NCT03665415
123 A Pilot Study of Primary Care Stepping Stones Triple P for Children With Autism Completed NCT02236650
124 Clinical Testing of a Real-Time Behavior Measurement Tool: Measuring Outcomes for CHAnge Completed NCT03229928
125 An Efficacy Trial of Milieu Teaching Language Intervention in Children With Language Disorders Completed NCT01975922
126 Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome: The Effectiveness of a Family-based Training Completed NCT03135236
127 Genetics and Physiology of Social Anxiety in Fragile X Completed NCT00879515
128 Conventional Versus Mindfulness Intervention in Parents of Children With Disabilities Completed NCT01110343
129 Randomized Trial of Parent Training for Young Children With Autism Completed NCT01233414
130 Methylphenidate for Hyperactivity and Impulsiveness in Children and Adolescents With Pervasive Developmental Disorders Completed NCT00025779 methylphenidate;guanfacine
131 Topiramate Effects on SIB in Prader-Willi Syndrome Completed NCT00065923 Topiramate
132 Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism Completed NCT01563003
133 Using the Prevent-Teach-Reinforce Model to Reduce Problem Behaviors in Children With Autism Spectrum Disorders Completed NCT02153203
134 A Randomized Trial of a Structured Social Skills Development Progam for Children With Autism Spectrum Disorders Completed NCT02147236
135 Using Mobile Technology to Reduce Stereotypy in Children With Autism Spectrum Disorders Completed NCT02124720
136 The Development of the Pediatric Eating Assessment Tool (PEDI-EAT-10) Completed NCT02909127
137 Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients. A Prospective Randomized Trial Completed NCT02329509
138 Study on the Phenotype of Language in Preterm Born Children at 5 Years of Age Completed NCT02988570
139 Tertiary Care Based Visual Developmental Diseases Management Model Among Preschool Children in China: a Cluster Randomized Controlled Trial Completed NCT03251456
140 Understanding Caregiver Adaptation to Pervasive Developmental Disorders Completed NCT00496210
141 Enhancing Communication Between Children in EI and Their Depressed Mothers Completed NCT03480841
142 A Feasibility Study to Determine the Acceptability and Impact of an Exercise Intervention for Children With Neurodevelopmental Difficulties and Sleep Problems Completed NCT04416789
143 Development of a Resiliency Training Program for Parents of Children With Specific Learning Disabilities Completed NCT02772432
144 Role of Ethnicity and Environment on Regulation of Response Towards Sensory Stimulation in Children: A Neurophysiological Study Completed NCT02878824
145 Pilot Trial of a Social Skills Group Treatment (Secret Agent Society Program) for Youth With Anxiety, ADHD, or Autistic Disorder Completed NCT02574273
146 Shared Decision Making to Improve Care and Outcomes for Children With Autism Completed NCT01921244
147 Computerized Cognitive Rehabilitation in Children After Severe Malaria Completed NCT01743417
148 Effects of a Parental Training Program Using Group-based Acceptance and Commitment Therapy for Managing Children With Asthma: a Randomized Controlled Trial Completed NCT02405962
149 Magnetic Resonance Imaging in Children and Adolescents With Autism and Multiple Complex Developmental Disorders Completed NCT00161135
150 Neural Development and Its Influencing Factors in Premature Infants With Chronic Lung Disease Completed NCT00155831
151 Biomarkers of Central Nervous System Tetrahydrobiopterin Concentration and Response to Tetrahydrobiopterin Supplementation in Children With Idiopathic Cognitive Developmental Disorders Completed NCT01141595 sapropterin dihydrochloride
152 Efficacy and Feasibility of a Tele-mental Health Intervention to Support Parents Caring for a Technology-dependent Child at Home Completed NCT03578289
153 Clinical and Genetic Studies on Holoprosencephaly Completed NCT00088426
154 A Randomized, Open-Label Study of Recombinant Human Growth Hormone (r-hGH) in Children With HIV-Associated Growth Failure Completed NCT00006143 Somatropin
155 PET Imaging of GABA Receptors in Succinic Semialdehyde Dehydrogenase Deficiency Completed NCT00246870
156 Study of the Long-term Outcomes of Nitric Oxide for Ventilated Premature Babies Completed NCT00234247
157 Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study) Completed NCT02692846
158 Predicting Developmental Disability Type and Mental Retardation Level in Children Who Were Diagnosed in General Developmental Delay Completed NCT01430845
159 Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder Completed NCT00902798
160 Advanced Grandparental Age as a Risk Factor for Autism and Other Pervasive Developmental Disorders Completed NCT00464477
161 CareToy - A Modular Smart System for Infants' Rehabilitation at Home Based on Mechatronic Toys Completed NCT01990183
162 Cortical Excitability in Succinic Semialdehyde Dehydrogenase Deficiency Completed NCT00132366
163 Family-Centered Neuropsychoeducational In-NICU Intervention for Preterm Infants With Severe Intrauterine Growth Retardation and for Their Families Completed NCT00914108
164 Effectiveness of Visual Pedagogy-assisted Tooth-brushing Training Among Preschoolers With Special Needs for Oral Health Promotion Completed NCT03522337
165 GroundsKeeper: A Qualitative Study of Applied Game-based Interactives in Special Education Programs Completed NCT01808066
166 Project RESPECT-Plus: Recovery, Empowerment, Social Services, Prenatal Care, Education and Community Treatment-Plus Completed NCT02334111
167 Using Mobile Health Technology to Optimize Communication Outcomes for South African Children With Developmental Disabilities Completed NCT03409406
168 Use of Functional Behavioral Assessments to Evaluate Stereotypy and Repetitive Behaviors in a Double-blind, Placebo Controlled Trials of Various Medications Used to Treat Children With Autism. Completed NCT00211770
169 Comparison of DSM-IV-TR and DSM-5 Diagnostic Criteria for Autism Spectrum Disorder Completed NCT02296502
170 Developing and Evaluating a Meta-cognitive Intervention Amongst Adolescents With Neuro-development Disabilities Completed NCT03618563
171 CIN001-HeadStart Navigator Intervention Completed NCT03499405
172 Home-based Pain Management Protocol for Children With Sickle Cell Disease Completed NCT00386048
173 Effect of Integrated Management of Childhood Maltreatment, Maternal Depression, Psychosocial Stimulation and Nutritional Intervention on Child Development - A Randomized Controlled Trial Completed NCT03031236
174 Wearable Sensors and Video Recording for Children (Birth to 24 Months) to Monitor Motor Development Recruiting NCT03770832
175 Development and Evaluation of a Novel Imitation-based Dog Assisted Intervention, 'DIAD Training', to Increase Joint Activity and Social Wellbeing for Adolescents With Developmental Disabilities. Recruiting NCT03462407
176 A Prospective Cohort Study to Examine the Improvement in Preschoolers' Participation as a Result of Occupational Therapy Intervention Recruiting NCT02774135
177 Clinical Trial of an Early Parenting Empowerment Intervention to Promote Socioemotional Development in Infants With Developmental Disabilities: Parent and Infant Behavioral, Neuroendocrine and Epigenetics Outcomes Recruiting NCT03853564
178 Evaluating Parent Delivered Interventions for Children With Autism Recruiting NCT01882153
179 Anatomical Clinical Correlations. Neuropsychological and Brain Medical Imaging Study in Brain Damage Subjects 2 (CORAC2) Recruiting NCT03586258
180 Treatment of Disruptive Behaviors in Fragile X Syndrome Recruiting NCT03510156
181 A Center Based Early Intervention Program For Preschoolers With Developmental Disorders Recruiting NCT04026386
182 Integrating WIC With Early Childhood Systems of Developmental Care Recruiting NCT04159038
183 Families of Youth With Developmental Disabilities: A Theory-Based Intervention Recruiting NCT03495440
184 Does Timing Matter? Efficacy of Parent Provided, Therapist Supported, Motor and Cognitive Intervention for Infants Born Very Preterm in the First Months of Life Recruiting NCT03518736
185 Neonatal Seizure Registry - Developmental Functional EValuation Recruiting NCT04337697
186 Genetics of Epilepsy and Related Disorders Recruiting NCT01858285
187 The Multi-site Study of the Early Integrated Intervention for Child Brain-developmental Disorders in China Recruiting NCT03847402
188 Remote Delivery of Weight Management for Adults With Intellectual and Developmental Disabilities (IDD) Recruiting NCT03291509
189 Ultrasound Evaluation Versus Direct Measurement of Uterine Cavity Length: a Prospective Study Recruiting NCT04425577
190 Positive Emotion Regulation Training in Children, Adolescents and Young Adults With and Without Developmental Disorder Recruiting NCT02898298
191 Sensitivity of the Search for a Heterophory-Vertical-Labile (HV-Labile) for Ambulatory Screening for Specific Learning Disabilities (SLD) or Developmental Coordination Disorder (DCD). Recruiting NCT04122820
192 Individual and Family-based Approaches to Increase Physical Activity in Adolescents With IDD Recruiting NCT03684512
193 Evaluate the Acceptability (Including Gastro Intestinal Tolerance and Compliance) of a Paediatric Tube-feed Formula Ingredients Derived From Real Food for Children Over 12 Months of Age Recruiting NCT03718195
194 BRIGHT Coaching: A Randomized Controlled Trial on the Effectiveness of a Developmental Coach System to Empower Families of Children With Emerging Developmental Delay Recruiting NCT03880383
195 Living Well With a Disability Curriculum Adaptation Evaluation Plan Recruiting NCT03447119
196 Physical Activity and Cognitive Development in Children Recruiting NCT02542683
197 Risk Evaluation of Fetal Nervous System and Neurodevelopment Disorders in Infants of Women Exposed to Zika Virus Infection During Pregnancy Recruiting NCT02943304
198 Automatization of Counting Procedures in Children With Dyscalculia Recruiting NCT03354481
199 The Effect of Perinatal Stress on the Development of Preterm Infants Recruiting NCT02623400
200 Peri-operative Pain Assessment in Children Undergoing Orthopaedic Surgery Recruiting NCT04244760
201 Effectiveness of the WHO Caregivers Skills Training (CST) Program for Children With Developmental Disorders and Delays in Rural Community Settings in Pakistan: An Individual Randomized Controlled Trial (RCT) Recruiting NCT04255472
202 Cognitive Enhancement Therapy for Adult Autism Spectrum Disorder Recruiting NCT03170453
203 iVision - Development of a Game-based Therapy for Children With Cerebral Visual Impairment Recruiting NCT04051983
204 Exploration and Characterization of the Phenotypic and Genetic Profile of Patients With Early Onset Schizophrenia Associated With Autism Spectrum Disorder and Their First-degree Relatives (GenAuDiss). Recruiting NCT02565524
205 CDK13 Related Disorder : Clinical Phenotype, Neuropsychological Profile, Brain MRI Characteristics and Epigenetic Signature. Recruiting NCT04382573
206 Assessment of the Diagnostic Approach to Specific Language Disorders and Learning Using a New Calibrated Tool: the Modular Battery Tests Computerized (BMTi) Recruiting NCT03919357
207 Neurodevelopmental Outcomes at Three Years of Age in Very Preterm Infants (< 31 Weeks Gestational Age) or Very Low Birth Weight (< 1500 Grams) Randomized to Single Patient Rooms Compared to Open Bay Neonatal Intensive Care Unit Recruiting NCT03867669
208 Acceptance and Commitment Therapy Group, Navigator ACT for Parents to Children With Disabilities Recruiting NCT03830476
209 Word Learning in Children With Autism (Kansas Intellectual and Developmental Disabilities Research Center Project I) Recruiting NCT03419611
210 Effectiveness of a Web-based Acceptance and Commitment Therapy for Wellbeing of Parents With Children With Chronic and Developmental Conditions: A Randomized Controlled Trial Recruiting NCT04250012
211 Eye Tracking Technologies to Characterize and Optimize Visual Attending in Down Syndrome Recruiting NCT03764761
212 EMPATIA@Lecco - Tavolo 13: Mother-Infant Interaction Kinect Analysis (MIIKA) Recruiting NCT04288973
213 Reliability and Construct Validity of the Turkish Version of the Drooling Impact Scale Among Children With Cerebral Palsy Recruiting NCT04132765
214 Improving Math Deficits in Children With Dyscalculia by tRNS: a Randomized, Double-blind Study Recruiting NCT04242680
215 The MET Signaling System, Autism and Gastrointestinal Dysfunction Recruiting NCT02442115
216 Basic and Clinical Studies in Reinforcing Positive Behaviors in Intellectual and Developmental Disabilities Recruiting NCT03423940
217 Early Screening for Emotional, Behavioral and Autism Spectrum Disorders in Children With Functional Constipation. Recruiting NCT03614000
218 Early Intervention Playgroup Recruiting NCT03062371
219 The Home-Use of Semiconducting QUantum Excitonic Device: Image Converter/Sound Converter/Electromagnetic Converter to Improve Communicative Efforts, Speech, Language and Related Cognitive Functions in Children With Autism Recruiting NCT03222375
220 A Prospective Cohort Study of the Association Between Pregnancy Health and Offspring Developmental & Behavioral Outcomes(Multi-Centered) Recruiting NCT04017286
221 An Open-Label Trial of Oxytocin in Adolescents With Autism Spectrum Disorders Active, not recruiting NCT01931033 Intranasal Oxytocin
222 Weight Management for Adolescents With IDD Active, not recruiting NCT02561754
223 HealthMatters@24/7 Asynchronous Health Promotion eLearning for People Supporting Adults With Intellectual and Developmental Disabilities Active, not recruiting NCT03206164
224 Feasibility Test of a Pediatric Web-Based Care Planning Guide Active, not recruiting NCT03820011
225 Genetic Contributions to Autism Spectrum Disorders Active, not recruiting NCT01160783
226 Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder Active, not recruiting NCT01631851
227 Comparative Effectiveness of Therapy in Rare Diseases: Liver Transplantation vs. Conservative Management of Urea Cycle Disorders Active, not recruiting NCT02740153
228 A Prospective Pilot Study to Characterize the Impact on Families of Electronic Tracking Device Use by Children With Autism Spectrum Disorders Who Wander Active, not recruiting NCT03814902
229 Measuring the Effects of Therapeutic Horseback Riding on School-Age Children and Adolescents With Autism Spectrum Disorders Active, not recruiting NCT02301195
230 The Effect of New Holistic Early Intervention Approach (Explorer Babies): a Randomized Controlled Study Active, not recruiting NCT04203589
231 Early Identification and Service Linkage for Urban Children With Autism Active, not recruiting NCT02359084
232 Children's Autism Metabolome Project (CAMP): Development and Clinical Evaluation of the Stemina Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood Active, not recruiting NCT02548442
233 Health System Integration of Tools to Improve Primary Care for Autistic Adults Active, not recruiting NCT03234608
234 The Utility of MRI Scoring to Predict Neurodevelopmental Outcomes in Survivors Active, not recruiting NCT02249624
235 Intense Physiotherapies to Improve Function in Young Children With Cerebral Palsy Active, not recruiting NCT02167022
236 Parent-Child Reciprocity and the Effectiveness of a Parent-Assisted Social Skills Training Program for Adolescents With Autism Spectrum Disorder Active, not recruiting NCT03354923
237 Oral Health Promotion Strategy for Persons With Intellectual/Developmental Disabilities Enrolling by invitation NCT03834064
238 Quality of Life and Stress in Parents of Children With Developmental Disabilities and Chronic Disease Enrolling by invitation NCT03602378
239 Recombinant Human Erythropoietin Improve Neurodevelopmental Outcomes in Extremely Preterm Infants Enrolling by invitation NCT02745990 Recombinant human erythropoietin;Normal saline
240 The Effects of Dance Training on Postural Stability in Adults With Developmental Disabilities Enrolling by invitation NCT03660423
241 DDX3X Related Disorder : Clinical Phenotype, Neuropsychological Profile and Epigenetic Signature. Enrolling by invitation NCT04436588
242 Single Ventricle Reconstruction III: Brain Connectome and Neurodevelopmental Outcomes Enrolling by invitation NCT02692443
243 Optimizing the Management of Pain and Irritability of Unknown Origin (PIUO) in Children With Severe Neurological Impairment Enrolling by invitation NCT03464773
244 Child Developmental Health, Maternal Psychosocial Distress, and Health System Costs at 18 Months Corrected Age: Effectiveness of a Cluster Randomized Controlled Trial of Family Integrated Care in Level II NICUs Enrolling by invitation NCT03337659
245 Engagement in Healthy Communities for People With Intellectual and Developmental Disabilities Not yet recruiting NCT04182347
246 The Use Of Music Therapy In Autism Spectrum Disorder Not yet recruiting NCT03267095
247 Lung Ultrasound for Early Detection of Silent and Apparent aspiratioN in Infants and Young CHildren With Cerebral Palsy and Other Developmental Disabilities: a New Fast, Safe, Cost-effective Infant-friendly Imaging Tool to Easily Monitor Feeding , Improve Outcomes and Reduce Morbidities (LUNCH) Not yet recruiting NCT04253951
248 English Title: Extreme Challenges - Psychopathology, Treatment Organization and Experiences Among Psychiatric Inpatients With Severe Self-harming Behavior in Norway Not yet recruiting NCT03768674
249 A Clinical Trial for Treatment-Resistant Subtypes of Self-Injurious Behavior Suspended NCT03995966
250 Examination of Differential Valuation of Leisure Items and Attention as Reinforcers in Children With Autism Suspended NCT03152383
251 Memantine in Adult Autism Spectrum Disorder Terminated NCT01078844 memantine;Placebo
252 Longitudinal and Biological Study of Childhood Disintegrative Disorder Terminated NCT00004458
253 A Prospective Study Comparing the Mifne Approach of Treating Childhood Autism With Routine Standard Treatment Terminated NCT00445471
254 Neurocircuitry of Autism- fMRI and Transcranial Magnetic Stimulation Studies Terminated NCT01553240
255 Assessing Suicide Risk in Adolescents With Developmental Delays: Development of a Screening Tool Terminated NCT01517126
256 Neuroimmune Activation in Austism: Imaging Translocator Protein Using Positron Emission Tomography (PET) Terminated NCT01322555
257 Enhancing Communication Between Children in EI and Their Depressed Mothers Withdrawn NCT03164642
258 Feasibility Study: Improvised Music to Enhance the Effectiveness of Intensive Interaction in Developing Interpersonal Communication of Profoundly Intellectually Disabled Children and Young People Withdrawn NCT03188016
259 Hypothermia as Neuroprotection During ECMO: Is Brain MRI a Biomarker of Outcomes? Withdrawn NCT01675388

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# Title Authors PMID Year
1
Truncating de novo mutations in the Krüppel-type zinc-finger gene ZNF148 in patients with corpus callosum defects, developmental delay, short stature, and dysmorphisms. 6 56
27964749 2016
2
Barriers to transition from pediatric to adult care for patients with Dravet syndrome: A focus group study of caregivers. 61
32422576 2020
3
Comparing Computer-Assisted and Teacher-Implemented Visual Matching Instruction for Children with ASD and/or Other DD. 61
30864058 2020
4
Application of a human mesoderm tissue elongation system in vitro derived from human induced pluripotent stem cells to risk assessment for teratogenic chemicals. 61
32092576 2020
5
Participation in Social Skills Therapy is Associated With Enhanced Recall Memory by Children With Down Syndrome: An Exploratory Study. 61
30961353 2020
6
Indigenous Australians with autism: A scoping review. 61
31928063 2020
7
Parental Age at Conception and the Relationship with Severity of Autism Symptoms. 61
31355686 2020
8
Factors predicting school staff's responsivity toward students with intellectual and developmental disability and complex communication needs. 61
32388042 2020
9
Psychometric Properties and Utility of the Social Vulnerability Questionnaire for Individuals with Intellectual and Developmental Disabilities. 61
29873017 2020
10
Teaching students with intellectual and developmental disabilities to calculate cost after discounts via schematic diagrams. 61
32388043 2020
11
Sleep, brains, and behavior across ten neurodevelopmental disorders: Introduction to the special issue on sleep in developmental disabilities. 61
32416554 2020
12
Prevalence of renewal of problem behavior: Replication and extension to an inpatient setting. 61
32578889 2020
13
Coping with caregiving: Humor styles and health outcomes among parents of children with disabilities. 61
32497974 2020
14
Predictors of Annual and Early Separations Among Direct Support Professionals: National Core Indicators Staff Stability Survey. 61
32484882 2020
15
They Care for Others, But What About Themselves? Understanding Self-Care Among DSPs' and Its Relationship to Professional Quality of Life. 61
32484886 2020
16
Long-term motor and cognitive function in the children of women with inflammatory bowel disease. 61
32497181 2020
17
A preliminary evaluation of still face images by deep learning: A potential screening test for childhood developmental disabilities. 61
32540607 2020
18
Parent survey of sleep problems among children with CHARGE syndrome. 61
32248059 2020
19
Perceptions of social support: comparisons between fathers of children with autism spectrum disorder and fathers of children without developmental disabilities. 61
31808233 2020
20
Barriers to and Facilitators of Successful Early School Transitions for Children with Autism Spectrum Disorders and Other Developmental Disabilities: A Systematic Review. 61
30806855 2020
21
A nurses' ethical commitment to people with intellectual and developmental disabilities. 61
32228209 2020
22
Empowerment in Polish fathers of children with autism and Down syndrome: the role of social support and coping with stress - a preliminary report. 61
31418969 2020
23
Estimated Prevalence of Asthma in US Children With Developmental Disabilities. 61
32543699 2020
24
Behavioral Approaches to Assessment and Early Intervention for Severe Problem Behavior in Intellectual and Developmental Disabilities. 61
32443989 2020
25
Sterilization of Men with Developmental Disabilities: A Historical Perspective and Modern Conundrum. 61
32209351 2020
26
Using telehealth to teach valued skills to adults with intellectual and developmental disabilities. 61
32542669 2020
27
Brief Report: Obesogenic Behaviors of Children with Developmental Disabilities During Summer. 61
32533383 2020
28
Use of complementary and alternative medicine treatments by mothers of children with developmental disabilities: a cross sectional study. 61
32362016 2020
29
Another Vision From the Coronavirus Health Crisis in Spain: The Perspective From the Plena inclusión Developmental Disabilities Associative Movement. 61
32563540 2020
30
The prevalence and health status of people with developmental disabilities in provincial prisons in Ontario, Canada: A retrospective cohort study. 61
32529696 2020
31
Reply to: Another Vision From the Coronavirus Health Crisis in Spain: The Perspective From the Plena inclusión Developmental Disabilities Associative Movement. 61
32563541 2020
32
Asian Immigrant Parents' Role Enactment While Accessing and Using Services for Their Child With Developmental Disabilities in the United States: A Meta-Synthesis Study. 61
32564671 2020
33
Corrigendum to 'The role of ADHD symptoms in the relationship between academic achievement and psychopathological symptoms' Research in Developmental Disabilities 97 (2020) 103552. 61
32565004 2020
34
From the DSP Perspective: Exploring the Use of Practices That Align With Trauma-Informed Care in Organizations Serving People With Intellectual and Developmental Disabilities. 61
32484883 2020
35
Cultivating Passion through Collaborative Art: A Dialogic Exploration of Disability, Storytelling, and Social Change. 61
30947540 2020
36
"I wouldn't know where to start": Perspectives from clinicians, agency leaders, and autistic adults on improving community mental health services for autistic adults. 61
31674198 2020
37
The Impact of Invisible Illness and Invisible Disability on Music Therapy Practica Students. 61
32201892 2020
38
Umbilical cord blood stem cell therapy in premature brain injury: Opportunities and challenges. 61
31797400 2020
39
Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish. 61
32173352 2020
40
Adaptation to Technology Use in Families of Children With Complex Communication Needs: An Integrative Review and Family Theory Application. 61
32389060 2020
41
Teledentistry: remote observation of patients with special needs. 61
32348247 2020
42
Editorial: Reducing Aggressive Episodes in Psychiatrically Hospitalized Children: Does Behavior Modification Work? 61
31655102 2020
43
Physical Activity and Sedentary Behavior Among U.S. Children With and Without Down Syndrome: The National Survey of Children's Health. 61
32357102 2020
44
Measurement invariance of the Positive Gains Scale in families of children with and without disabilities. 61
32438248 2020
45
Overt planning behaviors during writing in school-age children with autism spectrum disorder and attention-deficit/hyperactivity disorder. 61
32203886 2020
46
Examining the Role of Language in Play Among Children With and Without Developmental Disabilities. 61
32402229 2020
47
Attachment and child behaviour and emotional problems in autism spectrum disorder with intellectual disability. 61
31746131 2020
48
Seeing strengths: Young adults and their siblings with autism or intellectual disability. 61
31919930 2020
49
The Caregiver Health Effects of Caring for Young Children with Developmental Disabilities: A Meta-analysis. 61
32048172 2020
50
Improving Pediatric Hearing Testing for Children with Developmental Delays: The Effects of Video Modeling on Child Compliance and Caregiver Stress. 61
32516820 2020
51
A Component Analysis of the Mindfulness-Based Positive Behavior Support (MBPBS) Program for Mindful Parenting by Mothers of Children with Autism Spectrum Disorder. 61
32421103 2020
52
Delirium and Developmental Disability: Improving Specificity of a Pediatric Delirium Screen. 61
32106184 2020
53
Intellectual and developmental disability and COVID-19 case-fatality trends: TriNetX analysis. 61
32473875 2020
54
From stigma to acceptance: Intellectual and developmental disabilities in Central China. 61
32425086 2020
55
Analyzing essays about treating adults with special health care needs and intellectual and developmental disabilities. 61
31985057 2020
56
Influence of adaptive behaviour on the quality of life of adults with intellectual and developmental disabilities. 61
31960564 2020
57
Decisional Capacity for Informed Consent in Males and Females with Fragile X Syndrome. 61
30825084 2020
58
Development of Deaf Adults with Intellectual Disability in a Therapeutic Living Community. 61
32313924 2020
59
Using technology and remote support services to promote independent living of adults with intellectual disability and related developmental disabilities. 61
32050053 2020
60
The complexity of tooth brushing among older adults with intellectual disabilities: Findings from a nationally representative survey. 61
32439304 2020
61
Children With Intellectual and Developmental Disabilities as Organ Transplantation Recipients. 61
32312907 2020
62
An Exploration of Health Behaviors in a Mind-Body Resilience Intervention for Parents of Children with Developmental Disabilities. 61
32412991 2020
63
Exploring health and wellness among Native American adults with intellectual and/or developmental disabilities and their family caregivers. 61
31436363 2020
64
Teaching caregivers to implement mand training using speech generating devices. 61
31478192 2020
65
A comparison of displacement and reinforcer potency for typically developing children. 61
31486076 2020
66
DRA contingencies promote improved tolerance to delayed reinforcement during FCT Compared to DRO and fixed-time schedules. 61
32266724 2020
67
Olivia Juliette Hooker (1915-2018). 61
32250146 2020
68
Diabetes self-care behaviors in adults with disabilities: A systematic review. 61
31691458 2020
69
Evaluation and Restoration of Competence to Stand Trial: Intercepting the Forensic System Using the Sequential Intercept Model. 61
32237983 2020
70
Hózhó: Promoting sleep health among Navajo caregivers. 61
32044276 2020
71
Trauma-informed care in the context of intellectual and developmental disability services: Perceptions of service providers. 61
32319343 2020
72
Hospital admissions in children with developmental disabilities from ethnic minority backgrounds. 61
31498429 2020
73
An Examination of the Validity of the Health Risk Screening Tool: Predicting Mortality in People With Intellectual Disabilities. 61
32295856 2020
74
Physical activity guideline compliance among a national sample of children with various developmental disabilities. 61
31875836 2020
75
Disparities in the Use of Guideline-Based Pharmacotherapy Exist for Atherosclerotic Cardiovascular Disease and Heart Failure Patients Who Have Intellectual/Developmental Disabilities in a Commercially Insured Database. 61
32336108 2020
76
Teaching students with autism spectrum disorder to tolerate haircutting. 61
32320076 2020
77
Systematic Review of Recent Pediatric Down Syndrome Neuropsychology Literature: Considerations for Regression Assessment and Monitoring. 61
32251042 2020
78
Improving accepting and giving compliments with individuals with developmental disabilities. 61
31833057 2020
79
A Hearing Screening Pilot Study With Students With Significant Cognitive Disabilities. 61
31951500 2020
80
An evaluation of outcomes for service users with an intellectual disability admitted to an assessment and treatment unit. 61
32319332 2020
81
Intellectual and Developmental Disabilities Research Centers: A Multidisciplinary Approach to Understand the Pathogenesis of Methyl-CpG Binding Protein 2-related Disorders. 61
32360592 2020
82
Exploring the nature and correlates of caregiving among parents of adults with intellectual and developmental disabilities. 61
32307849 2020
83
Identifying Predictors for Enhanced Outcomes for People With Intellectual and Developmental Disabilities. 61
32240047 2020
84
A Meta-analysis of Challenging Behavior Interventions for Students with Developmental Disabilities in Inclusive School Settings. 61
31907730 2020
85
Stakeholders' engagement in co-producing policy-relevant knowledge to facilitate employment for persons with developmental disabilities. 61
32303228 2020
86
Breaking tradition: Increasing physical activity and reducing sedentary time of children with developmental disabilities. 61
31776073 2020
87
Interventions for inappropriate sexual behavior in individuals with intellectual and developmental disabilities: A brief review. 61
32346893 2020
88
Impact of a Medicaid policy on preventive oral health services for children with intellectual disabilities, developmental disabilities, or both. 61
32081299 2020
89
Racial and Ethnic Disparities in Birth Outcomes and Labor and Delivery Charges Among Massachusetts Women With Intellectual and Developmental Disabilities. 61
32240049 2020
90
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Effects of a Universal School-Based Mental Health Program on the Self-concept, Coping Skills, and Perceptions of Social Support of Students with Developmental Disabilities. 61
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