MCID: GLM001
MIFTS: 30

Glomeruloid Hemangioma

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Glomeruloid Hemangioma

MalaCards integrated aliases for Glomeruloid Hemangioma:

Name: Glomeruloid Hemangioma 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:486
NCIt 51 C27505
UMLS 74 C1304511

Summaries for Glomeruloid Hemangioma

MalaCards based summary : Glomeruloid Hemangioma is related to poems syndrome and hemangioma. An important gene associated with Glomeruloid Hemangioma is MYOM2 (Myomesin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Cell adhesion molecules (CAMs). Affiliated tissues include skin and endothelial, and related phenotypes are hematopoietic system and immune system

Wikipedia : 77 Glomeruloid hemangioma is a distinctive vascular neoplasm first described in 1990 when found to be... more...

Related Diseases for Glomeruloid Hemangioma

Diseases related to Glomeruloid Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 77)
# Related Disease Score Top Affiliating Genes
1 poems syndrome 31.4 MYOM2 VEGFA
2 hemangioma 30.5 CD34 FLT1 PECAM1 VEGFA
3 myeloma, multiple 29.5 CD34 MYOM2 PTPRC VEGFA
4 median neuropathy 10.3 MYOM2 VEGFA
5 radiation proctitis 10.2 PECAM1 VEGFA
6 hydrocele 10.2 PECAM1 VEGFA
7 angiodysplasia 10.2 ENG VEGFA
8 kaposiform hemangioendothelioma 10.2 CD34 PECAM1
9 pediatric angiosarcoma 10.2 CD34 VEGFA
10 angiokeratoma circumscriptum 10.2 FLT1 VEGFA
11 microcystic meningioma 10.2 FLT1 VEGFA
12 drug-induced lupus erythematosus 10.2 ENG VEGFA
13 skin hemangioma 10.1 FLT1 VEGFA
14 epithelioid hemangioendothelioma 10.1 FLT1 VEGFA
15 lipodermatosclerosis 10.1 FLT1 VEGFA
16 cancer-associated retinopathy 10.1 FLT1 VEGFA
17 telangiectasis 10.1 ENG VEGFA
18 twin-to-twin transfusion syndrome 10.1 ENG FLT1
19 congenital lipomatous overgrowth, vascular malformations, and epidermal nevi 10.1 ENG PECAM1
20 interstitial emphysema 10.1 CD34 FLT1
21 lymphangiosarcoma 10.1 CD34 VEGFA
22 alveoli adenoma 10.1 CD34 FLT1
23 arteriovenous malformation 10.0 ENG VEGFA
24 liver inflammatory pseudotumor 10.0 CD34 PTPRC
25 multicentric castleman disease 10.0
26 castleman disease 10.0
27 plasmacytoma 10.0
28 tafro syndrome 10.0
29 vulvar sarcoma 10.0 CD34 PTPRC
30 chronic monocytic leukemia 10.0 CD34 PTPRC
31 acute mountain sickness 10.0 FLT1 VEGFA
32 placental abruption 10.0 ENG FLT1
33 arteriovenous malformations of the brain 10.0 ENG VEGFA
34 juvenile nasopharyngeal angiofibroma 10.0 ENG PECAM1 VEGFA
35 mature b-cell neoplasm 10.0 MYOM2 PTPRC
36 breast carcinoma in situ 10.0 FLT1 VEGFA
37 capillary hemangioma 10.0 FLT1 PECAM1 VEGFA
38 angiosarcoma 10.0 FLT1 PECAM1 VEGFA
39 corneal neovascularization 9.9 FLT1 VEGFA
40 retina lymphoma 9.9 CD34 CD68
41 sternum cancer 9.9 CD34 CD68
42 adult xanthogranuloma 9.9 CD34 CD68
43 hemangioma of liver 9.9 CD34 CD68
44 spleen cancer 9.9 CD34 CD68
45 mixed liposarcoma 9.9 CD34 CD68
46 placental insufficiency 9.9 FLT1 VEGFA
47 ischemic fasciitis 9.9 CD34 CD68
48 nodular tenosynovitis 9.9 CD68 PTPRC
49 aleukemic leukemia cutis 9.9 CD34 CD68
50 malignant giant cell tumor of soft parts 9.9 CD68 PTPRC

Graphical network of the top 20 diseases related to Glomeruloid Hemangioma:



Diseases related to Glomeruloid Hemangioma

Symptoms & Phenotypes for Glomeruloid Hemangioma

MGI Mouse Phenotypes related to Glomeruloid Hemangioma:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CD34 CD68 ENG FLT1 PECAM1 PTPRC
2 immune system MP:0005387 9.1 CD34 CD68 FLT1 PECAM1 PTPRC VEGFA

Drugs & Therapeutics for Glomeruloid Hemangioma

Search Clinical Trials , NIH Clinical Center for Glomeruloid Hemangioma

Genetic Tests for Glomeruloid Hemangioma

Anatomical Context for Glomeruloid Hemangioma

MalaCards organs/tissues related to Glomeruloid Hemangioma:

42
Skin, Endothelial

Publications for Glomeruloid Hemangioma

Articles related to Glomeruloid Hemangioma:

(show all 18)
# Title Authors Year
1
Glomeruloid hemangioma associated with TAFRO syndrome. ( 29702119 )
2018
2
Glomeruloid Hemangioma as a Late Manifestation of POEMS Syndrome. ( 30665482 )
2018
3
Glomeruloid Hemangioma as a Marker for the Early Diagnosis of POEMS Syndrome. ( 28392663 )
2017
4
Cutaneous Glomeruloid Hemangioma: A Report on Two Cases and a Review of Literature. ( 28813760 )
2017
5
Glomeruloid hemangioma and POEMS syndrome. ( 27208909 )
2016
6
Glomeruloid hemangioma in normal individuals. ( 23716835 )
2013
7
Uterine glomeruloid hemangioma in a patient without POEMS syndrome. ( 22134630 )
2012
8
Glomeruloid hemangioma in POEMS syndrome: a report on two cases and a review of the literature. ( 22281906 )
2011
9
Glomeruloid hemangioma as a very early presenting sign of POEMS syndrome. ( 19614998 )
2009
10
Eosinophilic globules in 3 cases of glomeruloid hemangioma of the head and neck: a characteristic offering more evidence for thanatosomes with or without POEMS. ( 19033925 )
2008
11
Glomeruloid hemangioma. ( 18477219 )
2008
12
Glomeruloid hemangioma leading to a diagnosis of POEMS syndrome. ( 16781311 )
2006
13
Renal involvement in multicentric Castleman disease with glomeruloid hemangioma of skin and plasmacytoma. ( 16860182 )
2006
14
Glomeruloid hemangioma--a specific cutaneous marker of POEMS syndrome. ( 11589746 )
2001
15
Glomeruloid hemangioma in POEMS syndrome shows two different immunophenotypic endothelial cells. ( 10678704 )
2000
16
A case of glomeruloid hemangioma associated with multicentric Castleman's disease. ( 9650700 )
1998
17
Glomeruloid hemangioma. A cutaneous marker of POEMS syndrome. ( 8030771 )
1994
18
Glomeruloid hemangioma. A distinctive cutaneous lesion of multicentric Castleman's disease associated with POEMS syndrome. ( 2173428 )
1990

Variations for Glomeruloid Hemangioma

Expression for Glomeruloid Hemangioma

Search GEO for disease gene expression data for Glomeruloid Hemangioma.

Pathways for Glomeruloid Hemangioma

GO Terms for Glomeruloid Hemangioma

Cellular components related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.46 CD34 ENG PTPRC VEGFA
2 external side of plasma membrane GO:0009897 9.26 CD34 ENG PECAM1 PTPRC
3 cell periphery GO:0071944 8.8 CD34 PECAM1 PTPRC

Biological processes related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.7 CD34 ENG VEGFA
2 positive regulation of MAP kinase activity GO:0043406 9.56 FLT1 VEGFA
3 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.55 FLT1 VEGFA
4 vasculogenesis GO:0001570 9.54 ENG VEGFA
5 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.51 FLT1 VEGFA
6 sprouting angiogenesis GO:0002040 9.49 ENG VEGFA
7 branching involved in blood vessel morphogenesis GO:0001569 9.48 ENG VEGFA
8 leukocyte cell-cell adhesion GO:0007159 9.46 PECAM1 PTPRC
9 angiogenesis GO:0001525 9.46 ENG FLT1 PECAM1 VEGFA
10 artery morphogenesis GO:0048844 9.43 ENG VEGFA
11 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.4 FLT1 VEGFA
12 cardiac muscle fiber development GO:0048739 9.37 MYOM2 VEGFA
13 vascular endothelial growth factor signaling pathway GO:0038084 9.32 FLT1 VEGFA
14 negative regulation of protein autophosphorylation GO:0031953 9.26 ENG PTPRC
15 glomerular endothelium development GO:0072011 8.96 CD34 PECAM1
16 positive regulation of angiogenesis GO:0045766 8.92 CD34 ENG FLT1 VEGFA

Molecular functions related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.92 ENG PECAM1 PTPRC VEGFA

Sources for Glomeruloid Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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