MCID: GLM001
MIFTS: 31

Glomeruloid Hemangioma

Categories: Cancer diseases, Cardiovascular diseases

Aliases & Classifications for Glomeruloid Hemangioma

MalaCards integrated aliases for Glomeruloid Hemangioma:

Name: Glomeruloid Hemangioma 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:486
NCIt 49 C27505
UMLS 71 C1304511

Summaries for Glomeruloid Hemangioma

MalaCards based summary : Glomeruloid Hemangioma is related to poems syndrome and hemangioma. An important gene associated with Glomeruloid Hemangioma is MYOM2 (Myomesin 2), and among its related pathways/superpathways are Fluid shear stress and atherosclerosis and HIF-1 signaling pathway. Affiliated tissues include breast, bone and heart, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 74 Glomeruloid hemangioma is a distinctive vascular tumor first described in 1990 when found to be... more...

Related Diseases for Glomeruloid Hemangioma

Diseases related to Glomeruloid Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 249)
# Related Disease Score Top Affiliating Genes
1 poems syndrome 31.4 VEGFA MYOM2 IL6
2 hemangioma 30.2 VEGFA PECAM1 FLT1 ENG CD68 CD34
3 plasmacytoma 30.2 VEGFA PTPRC IL6
4 capillary hemangioma 30.0 VEGFA PECAM1 FLT1 CD34
5 plasma cell neoplasm 29.3 VEGFA SDC1 PTPRC MYOM2 IL6
6 myeloma, multiple 28.4 VEGFA SDC1 PTPRC MYOM2 IL6 FLT1
7 polyneuropathy 10.6
8 glomangioma 10.5 PECAM1 CD34
9 skin epithelioid hemangioma 10.5 PECAM1 CD34
10 central nervous system angiosarcoma 10.5 PECAM1 CD34
11 intravascular angioleiomyoma 10.5 PECAM1 CD34
12 heart fibrosarcoma 10.5 PECAM1 CD34
13 central nervous system hemangioma 10.5 PECAM1 CD34
14 ovarian angiosarcoma 10.5 PECAM1 CD34
15 conventional angiosarcoma 10.5 PECAM1 CD34
16 angiomyoma 10.5 PECAM1 CD34
17 aortic malignant tumor 10.5 PECAM1 CD34
18 gallbladder leiomyosarcoma 10.5 PECAM1 CD34
19 ovary sarcoma 10.5 PECAM1 CD34
20 colonic lymphangioma 10.4 PECAM1 CD34
21 benign perivascular tumor 10.4 PECAM1 CD34
22 liposarcoma of bone 10.4 PECAM1 CD34
23 kaposiform hemangioendothelioma 10.4 PECAM1 CD34
24 erythema elevatum diutinum 10.4 PECAM1 CD34
25 liver leiomyoma 10.4 PECAM1 CD34
26 hobnail hemangioma 10.4 PECAM1 CD34
27 breast hemangioma 10.4 PECAM1 CD34
28 breast angiosarcoma 10.4 PECAM1 CD34
29 acquired hemangioma 10.4 VEGFA PECAM1
30 heart sarcoma 10.4 PECAM1 CD34
31 vulvar leiomyoma 10.4 PECAM1 CD34
32 benign mesothelioma 10.4 PECAM1 CD34
33 bacillary angiomatosis 10.4 PECAM1 CD34
34 histiocytoid hemangioma 10.4 PECAM1 CD34
35 angiolipoma 10.4 PECAM1 CD34
36 radiation proctitis 10.4 VEGFA PECAM1
37 benign mesenchymoma 10.4 PECAM1 CD34
38 thyroid angiosarcoma 10.4 PECAM1 CD34
39 middle ear adenocarcinoma 10.4 PECAM1 CD68
40 streptococcal toxic-shock syndrome 10.4 MYOM2 IL6
41 adenoid squamous cell carcinoma 10.4 PECAM1 CD34
42 subungual glomus tumor 10.4 PECAM1 CD34
43 breast sarcoma 10.4 PECAM1 CD34
44 liver sarcoma 10.4 CD68 CD34
45 vaginal endometrial stromal sarcoma 10.4 CD68 CD34
46 infiltrating angiolipoma 10.4 VEGFA CD34
47 extraosseous osteosarcoma 10.4 CD68 CD34
48 indolent myeloma 10.4 MYOM2 IL6
49 cystic lymphangioma 10.4 PECAM1 CD34
50 vulvar benign neoplasm 10.4 PECAM1 CD34

Graphical network of the top 20 diseases related to Glomeruloid Hemangioma:



Diseases related to Glomeruloid Hemangioma

Symptoms & Phenotypes for Glomeruloid Hemangioma

MGI Mouse Phenotypes related to Glomeruloid Hemangioma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.97 CD34 CD68 ENG FLT1 IL6 PECAM1
2 homeostasis/metabolism MP:0005376 9.91 CD34 ENG FLT1 IL6 PECAM1 PRL
3 immune system MP:0005387 9.81 CD34 CD68 FLT1 IL6 PECAM1 PRL
4 integument MP:0010771 9.5 CD34 ENG IL6 PRL PTPRC SDC1
5 neoplasm MP:0002006 9.1 CD34 IL6 PRL PTPRC SDC1 VEGFA

Drugs & Therapeutics for Glomeruloid Hemangioma

Search Clinical Trials , NIH Clinical Center for Glomeruloid Hemangioma

Genetic Tests for Glomeruloid Hemangioma

Anatomical Context for Glomeruloid Hemangioma

MalaCards organs/tissues related to Glomeruloid Hemangioma:

40
Breast, Bone, Heart, Skin, B Cells, Spleen, Myeloid

Publications for Glomeruloid Hemangioma

Articles related to Glomeruloid Hemangioma:

(show all 27)
# Title Authors PMID Year
1
Papillary Hemangioma: An Under-Recognized Entity Not to Be Confused With Glomeruloid Hemangioma. 61
31592865 2019
2
Tufted-angioma-like lesion associated with vascular endothelial growth factor and interleukin-6 in TAFRO syndrome: Is it a common histological feature of multicentric Castleman disease/POEMS syndrome? 61
30632181 2019
3
Glomeruloid hemangioma associated with TAFRO syndrome. 61
29702119 2018
4
Glomeruloid Hemangioma as a Late Manifestation of POEMS Syndrome. 61
30665482 2018
5
Cutaneous Glomeruloid Hemangioma: A Report on Two Cases and a Review of Literature. 61
28813760 2017
6
Glomeruloid Hemangioma as a Marker for the Early Diagnosis of POEMS Syndrome. 61
28392663 2017
7
Glomeruloid hemangioma and POEMS syndrome. 61
27208909 2017
8
Contributions of Dr. Juan Rosai to the pathology of cutaneous vascular proliferations: A review of selected lesions. 61
27318413 2016
9
Glomeruloid hemangioma in normal individuals. 61
23716835 2013
10
Uterine glomeruloid hemangioma in a patient without POEMS syndrome. 61
22134630 2012
11
Glomeruloid hemangioma in POEMS syndrome: a report on two cases and a review of the literature. 61
22281906 2011
12
Glomeruloid hemangioma as a very early presenting sign of POEMS syndrome. 61
19614998 2009
13
[POEMS syndrome with an isolated lytic lesion and glomeruloid hemangiomas: report of one case]. 61
19701559 2009
14
Eosinophilic globules in 3 cases of glomeruloid hemangioma of the head and neck: a characteristic offering more evidence for thanatosomes with or without POEMS. 61
19033925 2008
15
Glomeruloid hemangioma. 61
18477219 2008
16
Renal involvement in multicentric Castleman disease with glomeruloid hemangioma of skin and plasmacytoma. 61
16860182 2006
17
Glomeruloid hemangioma leading to a diagnosis of POEMS syndrome. 61
16781311 2006
18
Vascular tumors of the skin: a selective review. 61
15912727 2004
19
Reactive angioendotheliomatosis of the intestine. 61
15043317 2004
20
Glomeruloid hemangioma--a specific cutaneous marker of POEMS syndrome. 61
11589746 2001
21
Glomeruloid hemangioma in POEMS syndrome shows two different immunophenotypic endothelial cells. 61
10678704 2000
22
Endovascular papillary angioendothelioma (Dabska tumor) 61
9788271 1998
23
A case of glomeruloid hemangioma associated with multicentric Castleman's disease. 61
9650700 1998
24
Cutaneous vascular proliferation. Part II. Hyperplasias and benign neoplasms. 61
9418757 1997
25
Glomeruloid hemangioma. A cutaneous marker of POEMS syndrome. 61
8030771 1994
26
Acquired benign and "borderline" vascular lesions. 61
1730175 1992
27
Glomeruloid hemangioma. A distinctive cutaneous lesion of multicentric Castleman's disease associated with POEMS syndrome. 61
2173428 1990

Variations for Glomeruloid Hemangioma

Expression for Glomeruloid Hemangioma

Search GEO for disease gene expression data for Glomeruloid Hemangioma.

Pathways for Glomeruloid Hemangioma

GO Terms for Glomeruloid Hemangioma

Cellular components related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.55 VEGFA SDC1 PTPRC ENG CD34
2 cell periphery GO:0071944 9.13 PTPRC PECAM1 CD34
3 external side of plasma membrane GO:0009897 9.02 SDC1 PTPRC PECAM1 ENG CD34

Biological processes related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.81 VEGFA IL6 ENG CD34
2 positive regulation of protein phosphorylation GO:0001934 9.71 VEGFA PECAM1 ENG
3 positive regulation of MAPK cascade GO:0043410 9.63 PTPRC IL6 FLT1
4 angiogenesis GO:0001525 9.62 VEGFA PECAM1 FLT1 ENG
5 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.54 VEGFA PECAM1 IL6
6 artery morphogenesis GO:0048844 9.52 VEGFA ENG
7 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.49 VEGFA FLT1
8 vascular endothelial growth factor signaling pathway GO:0038084 9.48 VEGFA FLT1
9 positive regulation of angiogenesis GO:0045766 9.46 VEGFA FLT1 ENG CD34
10 cardiac muscle fiber development GO:0048739 9.43 VEGFA MYOM2
11 negative regulation of protein autophosphorylation GO:0031953 9.4 PTPRC ENG
12 glomerular endothelium development GO:0072011 9.26 PECAM1 CD34
13 sprouting angiogenesis GO:0002040 9.13 VEGFA FLT1 ENG
14 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 8.92 VEGFA PTPRC PECAM1 IL6

Sources for Glomeruloid Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....