MCID: GLM001
MIFTS: 28

Glomeruloid Hemangioma

Categories: Cancer diseases

Aliases & Classifications for Glomeruloid Hemangioma

MalaCards integrated aliases for Glomeruloid Hemangioma:

Name: Glomeruloid Hemangioma 12 15 72

Classifications:



External Ids:

Disease Ontology 12 DOID:486
NCIt 50 C27505
UMLS 72 C1304511

Summaries for Glomeruloid Hemangioma

MalaCards based summary : Glomeruloid Hemangioma is related to poems syndrome and skin hemangioma. An important gene associated with Glomeruloid Hemangioma is MYOM2 (Myomesin 2), and among its related pathways/superpathways are NF-kappaB Signaling and Cell adhesion molecules (CAMs). Affiliated tissues include skin and endothelial, and related phenotypes are hematopoietic system and immune system

Wikipedia : 75 Glomeruloid hemangioma is a distinctive vascular neoplasm first described in 1990 when found to be... more...

Related Diseases for Glomeruloid Hemangioma

Diseases related to Glomeruloid Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 89)
# Related Disease Score Top Affiliating Genes
1 poems syndrome 31.7 VEGFA MYOM2
2 skin hemangioma 30.5 VEGFA FLT1
3 capillary hemangioma 30.0 VEGFA PECAM1 FLT1
4 hemangioma 30.0 VEGFA PECAM1 FLT1 CD34
5 myeloma, multiple 29.0 VEGFA PTPRC MYOM2 CD34
6 polyneuropathy 10.6
7 median neuropathy 10.5 VEGFA MYOM2
8 radiation proctitis 10.4 VEGFA PECAM1
9 hydrocele 10.3 VEGFA PECAM1
10 angiodysplasia 10.3 VEGFA ENG
11 castleman disease 10.3
12 angiokeratoma circumscriptum 10.3 VEGFA FLT1
13 microcystic meningioma 10.3 VEGFA FLT1
14 drug-induced lupus erythematosus 10.3 VEGFA ENG
15 epithelioid hemangioendothelioma 10.2 VEGFA FLT1
16 cancer-associated retinopathy 10.2 VEGFA FLT1
17 lipodermatosclerosis 10.2 VEGFA FLT1
18 multicentric castleman disease 10.2
19 plasmacytoma 10.2
20 telangiectasis 10.2 VEGFA ENG
21 twin-to-twin transfusion syndrome 10.2 FLT1 ENG
22 congenital lipomatous overgrowth, vascular malformations, and epidermal nevi 10.2 PECAM1 ENG
23 nodular tenosynovitis 10.1 PTPRC CD68
24 malignant giant cell tumor of soft parts 10.1 PTPRC CD68
25 arteriovenous malformation 10.1 VEGFA ENG
26 acute mountain sickness 10.1 VEGFA FLT1
27 brain sarcoma 10.1 PTPRC CD68
28 hodgkin's lymphoma, lymphocytic depletion 10.1 PTPRC CD68
29 dowling-degos disease 1 10.1
30 thrombocytopenic purpura, autoimmune 10.1
31 angioma, tufted 10.1
32 hypothyroidism 10.1
33 thrombocytopenia 10.1
34 membranoproliferative glomerulonephritis 10.1
35 glomerulonephritis 10.1
36 acute kidney failure 10.1
37 purpura 10.1
38 hypertrichosis 10.1
39 littoral cell angioma of the spleen 10.1
40 tafro syndrome 10.1
41 placental abruption 10.1 FLT1 ENG
42 neurilemmoma of the fifth cranial nerve 10.1 PTPRC CD68
43 trigeminal nerve neoplasm 10.0 PTPRC CD68
44 kaposiform hemangioendothelioma 10.0 PECAM1 CD34
45 juvenile nasopharyngeal angiofibroma 10.0 VEGFA PECAM1 ENG
46 pediatric angiosarcoma 10.0 VEGFA CD34
47 mature b-cell neoplasm 10.0 PTPRC MYOM2
48 photokeratitis 10.0 PTPRC CD68
49 breast carcinoma in situ 10.0 VEGFA FLT1
50 arteriovenous malformations of the brain 10.0 VEGFA ENG

Graphical network of the top 20 diseases related to Glomeruloid Hemangioma:



Diseases related to Glomeruloid Hemangioma

Symptoms & Phenotypes for Glomeruloid Hemangioma

MGI Mouse Phenotypes related to Glomeruloid Hemangioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.5 CD34 CD68 ENG FLT1 PECAM1 PTPRC
2 immune system MP:0005387 9.1 CD34 CD68 FLT1 PECAM1 PTPRC VEGFA

Drugs & Therapeutics for Glomeruloid Hemangioma

Search Clinical Trials , NIH Clinical Center for Glomeruloid Hemangioma

Genetic Tests for Glomeruloid Hemangioma

Anatomical Context for Glomeruloid Hemangioma

MalaCards organs/tissues related to Glomeruloid Hemangioma:

41
Skin, Endothelial

Publications for Glomeruloid Hemangioma

Articles related to Glomeruloid Hemangioma:

(show all 26)
# Title Authors PMID Year
1
Tufted-angioma-like lesion associated with vascular endothelial growth factor and interleukin-6 in TAFRO syndrome: Is it a common histological feature of multicentric Castleman disease/POEMS syndrome? 38
30632181 2019
2
Glomeruloid hemangioma associated with TAFRO syndrome. 38
29702119 2018
3
Glomeruloid Hemangioma as a Late Manifestation of POEMS Syndrome. 38
30665482 2018
4
Cutaneous Glomeruloid Hemangioma: A Report on Two Cases and a Review of Literature. 38
28813760 2017
5
Glomeruloid Hemangioma as a Marker for the Early Diagnosis of POEMS Syndrome. 38
28392663 2017
6
Glomeruloid hemangioma and POEMS syndrome. 38
27208909 2017
7
Contributions of Dr. Juan Rosai to the pathology of cutaneous vascular proliferations: A review of selected lesions. 38
27318413 2016
8
Glomeruloid hemangioma in normal individuals. 38
23716835 2013
9
Uterine glomeruloid hemangioma in a patient without POEMS syndrome. 38
22134630 2012
10
Glomeruloid hemangioma in POEMS syndrome: a report on two cases and a review of the literature. 38
22281906 2011
11
Glomeruloid hemangioma as a very early presenting sign of POEMS syndrome. 38
19614998 2009
12
[POEMS syndrome with an isolated lytic lesion and glomeruloid hemangiomas: report of one case]. 38
19701559 2009
13
Eosinophilic globules in 3 cases of glomeruloid hemangioma of the head and neck: a characteristic offering more evidence for thanatosomes with or without POEMS. 38
19033925 2008
14
Glomeruloid hemangioma. 38
18477219 2008
15
Renal involvement in multicentric Castleman disease with glomeruloid hemangioma of skin and plasmacytoma. 38
16860182 2006
16
Glomeruloid hemangioma leading to a diagnosis of POEMS syndrome. 38
16781311 2006
17
Vascular tumors of the skin: a selective review. 38
15912727 2004
18
Reactive angioendotheliomatosis of the intestine. 38
15043317 2004
19
Glomeruloid hemangioma--a specific cutaneous marker of POEMS syndrome. 38
11589746 2001
20
Glomeruloid hemangioma in POEMS syndrome shows two different immunophenotypic endothelial cells. 38
10678704 2000
21
Endovascular papillary angioendothelioma (Dabska tumor) 38
9788271 1998
22
A case of glomeruloid hemangioma associated with multicentric Castleman's disease. 38
9650700 1998
23
Cutaneous vascular proliferation. Part II. Hyperplasias and benign neoplasms. 38
9418757 1997
24
Glomeruloid hemangioma. A cutaneous marker of POEMS syndrome. 38
8030771 1994
25
Acquired benign and "borderline" vascular lesions. 38
1730175 1992
26
Glomeruloid hemangioma. A distinctive cutaneous lesion of multicentric Castleman's disease associated with POEMS syndrome. 38
2173428 1990

Variations for Glomeruloid Hemangioma

Expression for Glomeruloid Hemangioma

Search GEO for disease gene expression data for Glomeruloid Hemangioma.

Pathways for Glomeruloid Hemangioma

GO Terms for Glomeruloid Hemangioma

Cellular components related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.46 VEGFA PTPRC ENG CD34
2 external side of plasma membrane GO:0009897 9.26 PTPRC PECAM1 ENG CD34
3 cell periphery GO:0071944 8.8 PTPRC PECAM1 CD34

Biological processes related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.7 VEGFA ENG CD34
2 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.56 VEGFA FLT1
3 positive regulation of MAP kinase activity GO:0043406 9.55 VEGFA FLT1
4 vasculogenesis GO:0001570 9.54 VEGFA ENG
5 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.51 VEGFA FLT1
6 sprouting angiogenesis GO:0002040 9.49 VEGFA ENG
7 leukocyte cell-cell adhesion GO:0007159 9.48 PTPRC PECAM1
8 branching involved in blood vessel morphogenesis GO:0001569 9.46 VEGFA ENG
9 angiogenesis GO:0001525 9.46 VEGFA PECAM1 FLT1 ENG
10 artery morphogenesis GO:0048844 9.43 VEGFA ENG
11 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.4 VEGFA FLT1
12 vascular endothelial growth factor signaling pathway GO:0038084 9.37 VEGFA FLT1
13 cardiac muscle fiber development GO:0048739 9.32 VEGFA MYOM2
14 negative regulation of protein autophosphorylation GO:0031953 9.26 PTPRC ENG
15 glomerular endothelium development GO:0072011 8.96 PECAM1 CD34
16 positive regulation of angiogenesis GO:0045766 8.92 VEGFA FLT1 ENG CD34

Molecular functions related to Glomeruloid Hemangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.92 VEGFA PTPRC PECAM1 ENG

Sources for Glomeruloid Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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