Glossopharyngeal Neuralgia

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Disease Ontology 12 DOID:14423 ICD9CM 36 352.1 MeSH 45 D020435 SNOMED-CT 69 43763009 ICD10 34 G52.1

ICD10 via Orphanet 35 G52.1 UMLS via Orphanet 75 C0154731 Orphanet 60 ORPHA221098 UMLS 74 C0154731 C0751941

NIH Rare Diseases : ⁵⁴ Glossopharyngeal neuralgia is a disorder that is associated with repeated episodes of severe pain in the tongue, throat, ear, and tonsils. These areas are all connected to the ninth cranial nerve, also called the glossopharyngeal nerve. Episodes of pain may last from a few seconds to a few minutes and usually occur on one side of the face. The pain may be triggered by swallowing, speaking, laughing, chewing, or coughing. Glossopharyngeal neuralgia is thought to be caused by irritation of the glossopharyngeal nerve, but the exact cause of the irritation is sometimes unknown. Laboratory and imaging tests can be used to diagnose the disorder and rule out serious underlying problems. The goal of treatment is to control pain, and the most effective drugs are anti-seizure medications and anti-depressants. Surgery to sever or take pressure off of the glossopharyngeal nerve may be needed in severe cases.

MalaCards based summary : Glossopharyngeal Neuralgia, also known as glossopharyngeal nerve diseases, is related to glossopharyngeal nerve disease and geniculate ganglionitis. An important gene associated with Glossopharyngeal Neuralgia is POMC (Proopiomelanocortin). Affiliated tissues include tongue, tonsil and testes.

NINDS : ⁵⁵ Glossopharyngeal neuralgia (GN) is a rare pain syndrome that affects the glossopharyngeal nerve (the ninth cranial nerve that lies deep within the neck)  and causes sharp, stabbing pulses of pain in the back of the throat and tongue, the tonsils, and the middle ear.  The excruciating pain of GN can last for a few seconds to a few minutes, and may return multiple times in a day or once every few weeks.  Many individuals with GN relate the attacks of pain to specific trigger factors such as swallowing, drinking cold liquids, sneezing, coughing, talking, clearing the throat, and touching the gums or inside the mouth.  GN can be caused by compression of the glossopharyngeal nerve, but in some cases, no cause is evident.  Like trigeminal neuralgia, it is associated with multiple sclerosis.  GN primarily affects the elderly.

Wikipedia : ⁷⁷ Neuralgia (Greek neuron, "nerve" + algos, "pain") is pain in the distribution of a nerve or nerves, as... more...

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