MNG2
MCID: GTR013
MIFTS: 13

Goiter, Multinodular 2 (MNG2)

Categories: Endocrine diseases

Aliases & Classifications for Goiter, Multinodular 2

MalaCards integrated aliases for Goiter, Multinodular 2:

Name: Goiter, Multinodular 2 58 74
Goiter, Multinodular, 2 58
Multinodular Goiter-2 13
Mng2 58

Characteristics:

OMIM:

58
Inheritance:
x-linked dominant

Miscellaneous:
mean age of onset 20.6 years


HPO:

33
goiter, multinodular 2:
Inheritance x-linked dominant inheritance


Classifications:



External Ids:

OMIM 58 300273
MedGen 43 C1846033
UMLS 74 C1846033

Summaries for Goiter, Multinodular 2

OMIM : 58 Multinodular goiter is a common disorder characterized by nodular enlargement of the thyroid gland. It occurs with a female:male ratio of 5:1 (summary by Capon et al., 2000). For additional phenotypic information and a discussion of genetic heterogeneity of multinodular goiter, see MNG1 (138800). (300273)

MalaCards based summary : Goiter, Multinodular 2, also known as goiter, multinodular, 2, is related to multinodular goiter. An important gene associated with Goiter, Multinodular 2 is MNG2 (Multinodular Goiter 2). Affiliated tissues include thyroid, and related phenotype is euthyroid multinodular goiter.

Related Diseases for Goiter, Multinodular 2

Diseases in the Multinodular Goiter family:

Goiter, Multinodular 2 Goiter, Multinodular 3

Diseases related to Goiter, Multinodular 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 multinodular goiter 11.4

Symptoms & Phenotypes for Goiter, Multinodular 2

Human phenotypes related to Goiter, Multinodular 2:

33
# Description HPO Frequency HPO Source Accession
1 euthyroid multinodular goiter 33 HP:0000866

Symptoms via clinical synopsis from OMIM:

58
Endocrine Features:
euthyroid multinodular goiter
thyroid volume 22-66ml (adults)

Head And Neck Neck:
thyroid goiter (diffuse or nodular)

Clinical features from OMIM:

300273

Drugs & Therapeutics for Goiter, Multinodular 2

Search Clinical Trials , NIH Clinical Center for Goiter, Multinodular 2

Genetic Tests for Goiter, Multinodular 2

Anatomical Context for Goiter, Multinodular 2

MalaCards organs/tissues related to Goiter, Multinodular 2:

42
Thyroid

Publications for Goiter, Multinodular 2

Variations for Goiter, Multinodular 2

Expression for Goiter, Multinodular 2

Search GEO for disease gene expression data for Goiter, Multinodular 2.

Pathways for Goiter, Multinodular 2

GO Terms for Goiter, Multinodular 2

Sources for Goiter, Multinodular 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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