MCID: GRN005
MIFTS: 32

Granuloma Inguinale

Categories: Infectious diseases, Oral diseases, Rare diseases, Reproductive diseases, Skin diseases
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Aliases & Classifications for Granuloma Inguinale

MalaCards integrated aliases for Granuloma Inguinale:

Name: Granuloma Inguinale 11 19 43 14 16 71 75 31 33
Donovanosis 11 19 33
Granuloma Inguinale Tropicum 33
Granuloma Pudendi Tropicum 33
Pudendal Ulcer 11

Classifications:



External Ids:

Disease Ontology 11 DOID:9113
ICD9CM 34 099.2
MeSH 43 D006100
NCIt 49 C3065
SNOMED-CT 68 186947000
ICD10 31 A58
ICD11 33 764124124
UMLS 71 C0018190

Summaries for Granuloma Inguinale

Disease Ontology: 11 A primary bacterial infectious disease that results in infection located in skin or located in mucosa of genital tract, has material basis in Klebsiella granulomatis, transmitted by sexual contact or transmitted by contact with the open sores. The infection has symptom painless genital ulcers.

MalaCards based summary: Granuloma Inguinale, also known as donovanosis, is related to lymphogranuloma venereum and chancroid, and has symptoms including painless genital ulcers An important gene associated with Granuloma Inguinale is FBXO39 (F-Box Protein 39). Affiliated tissues include skin, mucosa of genital tract and cervix.

GARD: 19 A condition resulting from infection by Klebsiella granulomati, which is characterized by ulcerative lesions of the genitalia.

Wikipedia: 75 Granuloma inguinale is a bacterial disease caused by Klebsiella granulomatis (formerly known as... more...

Related Diseases for Granuloma Inguinale

Diseases related to Granuloma Inguinale via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 80)
# Related Disease Score Top Affiliating Genes
1 lymphogranuloma venereum 26.6 YWHAB WASF2 TEPP SPAG8 SPAG17 QRSL1
2 chancroid 10.6
3 syphilis 10.4
4 klebsiella infection 10.2
5 osteomyelitis 10.1
6 penile cancer 10.1
7 penile benign neoplasm 10.1
8 filarial elephantiasis 10.1
9 rectal benign neoplasm 10.1
10 rectum cancer 10.1
11 phimosis 10.1
12 vaginal discharge 10.1
13 elephantiasis 10.1
14 acquired immunodeficiency syndrome 10.1
15 genital herpes 10.1
16 functional neutrophil defect 10.1
17 inclusion conjunctivitis 10.1 SPAG8 CPN1
18 pyosalpinx 10.1 ODF3 CT45A5 CT45A3
19 epididymis disease 10.0 FBXO39 CD4
20 salpingitis 10.0 ODF3 CD4
21 otitis media 10.0
22 suppressor of tumorigenicity 3 10.0
23 connective tissue benign neoplasm 10.0
24 mastoiditis 10.0
25 hydronephrosis 10.0
26 anogenital venereal wart 10.0
27 chlamydia 10.0
28 vulva cancer 10.0
29 balanoposthitis 10.0
30 urethritis 10.0
31 lymphadenitis 10.0
32 squamous cell carcinoma 10.0
33 vulva squamous cell carcinoma 10.0
34 vaginitis 10.0
35 vulvovaginitis 10.0
36 adenocarcinoma 10.0
37 mucinous adenocarcinoma 10.0
38 appendix adenocarcinoma 10.0
39 skin disease 10.0
40 primary syphilis 10.0
41 myoblastoma 10.0
42 penis squamous cell carcinoma 10.0
43 septic arthritis 10.0
44 scabies 10.0
45 actinomycosis 10.0
46 herpes simplex 10.0
47 molluscum contagiosum 10.0
48 orbital disease 10.0
49 miliary tuberculosis 10.0
50 malakoplakia 10.0

Graphical network of the top 20 diseases related to Granuloma Inguinale:



Diseases related to Granuloma Inguinale

Symptoms & Phenotypes for Granuloma Inguinale

Symptoms:

11
  • painless genital ulcers

Drugs & Therapeutics for Granuloma Inguinale

Search Clinical Trials, NIH Clinical Center for Granuloma Inguinale

Cochrane evidence based reviews: granuloma inguinale

Genetic Tests for Granuloma Inguinale

Anatomical Context for Granuloma Inguinale

Organs/tissues related to Granuloma Inguinale:

FMA: Skin, Mucosa Of Genital Tract
MalaCards : Skin, Cervix, Lymph Node, Uterus, Spinal Cord, Bone, Ovary

Publications for Granuloma Inguinale

Articles related to Granuloma Inguinale:

(show top 50) (show all 529)
# Title Authors PMID Year
1
Surveillance Snapshot: Donovanosis Among Active Component Service Members, U.S. Armed Forces, 2011-2020. 62
35320664 2021
2
Donovanosis in a Tunisian man: Atypical presentation and dermoscopic findings. 62
33943056 2021
3
[Brazilian Protocol for Sexually Transmitted Infections 2020: infections that cause genital ulcers]. 62
33729413 2021
4
Brazilian Protocol for Sexually Transmitted Infections, 2020: infections that cause genital ulcers. 62
34008730 2021
5
The changing epidemiology of genital ulcer disease in South Africa: has donovanosis been eliminated? 62
32075875 2020
6
Donovanosis. 62
33069513 2020
7
Recurrent myocardial infarction associated with vasculo-Beh├žet's disease: a case report. 62
33087010 2020
8
Sexually transmitted infections and human immunodeficiency virus coinfection: Scenario in Western India. 62
33817588 2020
9
Granuloma inguinale in a mentally retarded girl. 62
33817602 2020
10
Donovanosis and genital herpes coinfection in a woman with human immunodeficiency virus infection: A case letter. 62
32258347 2020
11
Donovanosis in a human immunodeficiency virus-positive female. 62
33063005 2020
12
Donovanosis in migrants: a clinical case series in an Italian dermatological hospital. 62
31313396 2019
13
Nonviral Sexually Transmitted Diseases. 62
31507345 2019
14
Sexually Transmitted Diseases in the Emergency Department. 62
30940365 2019
15
[Sexually Transmitted Infections in the Tropics]. 62
30324430 2018
16
2018 UK national guideline for the management of donovanosis. 62
29743002 2018
17
Donovanosis in a child victim of sexual abuse: response to doxycycline treatment. 62
30066775 2018
18
Usefulness and Utility of NACO Regime in the Management of Sexually Transmitted Infections: A Pilot Study. 62
29263538 2017
19
Skin diseases of the vulva: Infectious diseases. 62
28397528 2017
20
Granulomatous & histiocytic dermatitides. 62
28094163 2017
21
Donovanosis and squamous cell carcinoma: The relationship conundrum! 62
27535727 2017
22
Donovanosis With Bowen Disease. 62
28270316 2017
23
Tuberculosis of Glans Penis- A Rare Presentation. 62
28208927 2016
24
[A case of donovanosis acquired in France]. 62
27174716 2016
25
[Donovanosis (granuloma inguinale)]. 62
27773509 2016
26
Other sexually transmitted diseases chancroid and donovanosis. 62
27107782 2016
27
Nonhealing genital ulcer in AIDS: A diagnostic dilemma! 62
27890958 2016
28
2016 European guideline on donovanosis. 62
26882914 2016
29
Granuloma inguinale in a 51-year-old man. 62
27617463 2016
30
Medical Examination of Aliens--Revisions to Medical Screening Process. Final rule. 62
26812891 2016
31
Non-healing genital herpes mimicking donovanosis in an immunocompetent man. 62
25614521 2016
32
Deep Fungal Infections, Blastomycosis-Like Pyoderma, and Granulomatous Sexually Transmitted Infections. 62
26143434 2015
33
Donovanosis causing lymphadenitis, mastoiditis, and meningitis in a child. 62
26122163 2015
34
Travel-related sexually transmitted infections. 62
26726895 2015
35
The use of trimethoprim and sulfamethoxazole (TMP-SMX) in dermatology. 62
26774630 2015
36
Tuberculosis of the Penis: A Review of the Literature. 62
26435877 2015
37
Squamous cell carcinoma complicating donovanosis not a thing of the past! 62
24554002 2014
38
Pyoderma gangrenosum masquerading as Donovanosis. 62
26396454 2014
39
Genital donovanosis with malignant transformation: An interesting case report. 62
26396449 2014
40
Sexually transmitted infections. 62
24889293 2014
41
Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. 62
24559566 2014
42
Granuloma inguinale mimicking as squamous cell carcinoma of penis. 62
24958990 2014
43
Sexually transmitted diseases. 62
23958358 2013
44
Donovanosis: An incidental finding on Pap test. 62
24130421 2013
45
Genital Ulcer Disease: How Worrisome Is It Today? A Status Report from New Delhi, India. 62
26316954 2013
46
Infantile donovanosis presenting as external auditory canal polyps: a diagnostic trap. 62
23169417 2012
47
Genital elephantiasis due to donovanosis: forgotten but not gone yet ... 62
23155109 2012
48
Hypertrophic donavanosis in a young pregnant woman. 62
22840941 2012
49
Diagnosis and management of genital ulcers. 62
22335265 2012
50
Cytomorphology of unusual infectious entities in the Pap test. 62
22919422 2012

Variations for Granuloma Inguinale

Expression for Granuloma Inguinale

Search GEO for disease gene expression data for Granuloma Inguinale.

Pathways for Granuloma Inguinale

GO Terms for Granuloma Inguinale

Cellular components related to Granuloma Inguinale according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acrosomal vesicle GO:0001669 9.1 SPAG8 SPAG17 PRSS55

Biological processes related to Granuloma Inguinale according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 snRNA 3'-end processing GO:0034472 8.92 CT45A5 CT45A3

Sources for Granuloma Inguinale

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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