MCID: GRN005
MIFTS: 31

Granuloma Inguinale

Categories: Infectious diseases, Oral diseases, Rare diseases, Reproductive diseases, Skin diseases

Aliases & Classifications for Granuloma Inguinale

MalaCards integrated aliases for Granuloma Inguinale:

Name: Granuloma Inguinale 12 20 44 15 17 70 32
Donovanosis 12 20
Pudendal Ulcer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9113
ICD9CM 34 099.2
MeSH 44 D006100
NCIt 50 C3065
SNOMED-CT 67 186947000
ICD10 32 A58
UMLS 70 C0018190

Summaries for Granuloma Inguinale

Disease Ontology : 12 A primary bacterial infectious disease that results in infection located in skin or located in mucosa of genital tract, has material basis in Klebsiella granulomatis, transmitted by sexual contact or transmitted by contact with the open sores. The infection has symptom painless genital ulcers.

MalaCards based summary : Granuloma Inguinale, also known as donovanosis, is related to lymphogranuloma venereum and chancroid, and has symptoms including painless genital ulcers An important gene associated with Granuloma Inguinale is FBXO39 (F-Box Protein 39). Affiliated tissues include skin, mucosa of genital tract and cervix.

Wikipedia : 73 Granuloma inguinale is a bacterial disease caused by Klebsiella granulomatis (formerly known as... more...

Related Diseases for Granuloma Inguinale

Diseases related to Granuloma Inguinale via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
# Related Disease Score Top Affiliating Genes
1 lymphogranuloma venereum 26.7 WASF2 TEPP SPAG8 SPAG17 QRSL1 PRSS55
2 chancroid 10.6
3 syphilis 10.4
4 ophthalmia neonatorum 10.2 SPAG8 FBXO39
5 osteomyelitis 10.1
6 bacterial infectious disease 10.1
7 squamous cell carcinoma 10.1
8 phimosis 10.1
9 vaginal discharge 10.1
10 elephantiasis 10.1
11 acquired immunodeficiency syndrome 10.1
12 genital herpes 10.1
13 disease by infectious agent 10.1
14 inclusion conjunctivitis 10.1 SPAG8 FBXO39 CPN1
15 salpingitis 10.0 ODF3 CD4
16 otitis media 10.0
17 suppressor of tumorigenicity 3 10.0
18 gastrointestinal ulceration, recurrent, with dysfunctional platelets 10.0
19 mastoiditis 10.0
20 hydronephrosis 10.0
21 chlamydia 10.0
22 balanoposthitis 10.0
23 urethritis 10.0
24 lymphadenitis 10.0
25 rectum cancer 10.0
26 vaginitis 10.0
27 vulvovaginitis 10.0
28 adenocarcinoma 10.0
29 mucinous adenocarcinoma 10.0
30 appendix adenocarcinoma 10.0
31 skin disease 10.0
32 primary syphilis 10.0
33 myoblastoma 10.0
34 penis squamous cell carcinoma 10.0
35 septic arthritis 10.0
36 scabies 10.0
37 actinomycosis 10.0
38 herpes simplex 10.0
39 molluscum contagiosum 10.0
40 malakoplakia 10.0
41 splenomegaly 10.0
42 immune deficiency disease 10.0
43 leprosy 3 10.0
44 hansen's disease 10.0
45 epididymis disease 10.0 FBXO39 CD4
46 chlamydia pneumonia 10.0 CPN1 CD4
47 ovarian cancer 9.8
48 triiodothyronine receptor auxiliary protein 9.8
49 kala-azar 1 9.8
50 yaws 9.8

Graphical network of the top 20 diseases related to Granuloma Inguinale:



Diseases related to Granuloma Inguinale

Symptoms & Phenotypes for Granuloma Inguinale

Symptoms:

12
  • painless genital ulcers

Drugs & Therapeutics for Granuloma Inguinale

Search Clinical Trials , NIH Clinical Center for Granuloma Inguinale

Cochrane evidence based reviews: granuloma inguinale

Genetic Tests for Granuloma Inguinale

Anatomical Context for Granuloma Inguinale

The Foundational Model of Anatomy Ontology organs/tissues related to Granuloma Inguinale:

19
Skin, Mucosa Of Genital Tract

MalaCards organs/tissues related to Granuloma Inguinale:

40
Cervix, Uterus, Lymph Node, Spinal Cord, Ovary

Publications for Granuloma Inguinale

Articles related to Granuloma Inguinale:

(show top 50) (show all 523)
# Title Authors PMID Year
1
[Brazilian Protocol for Sexually Transmitted Infections 2020: infections that cause genital ulcers]. 61
33729413 2021
2
The changing epidemiology of genital ulcer disease in South Africa: has donovanosis been eliminated? 61
32075875 2020
3
Donovanosis. 61
33069513 2020
4
Donovanosis and genital herpes coinfection in a woman with human immunodeficiency virus infection: A case letter. 61
32258347 2020
5
Donovanosis in a human immunodeficiency virus-positive female. 61
33063005 2020
6
Donovanosis in migrants: a clinical case series in an Italian dermatological hospital. 61
31313396 2019
7
Nonviral Sexually Transmitted Diseases. 61
31507345 2019
8
Sexually Transmitted Diseases in the Emergency Department. 61
30940365 2019
9
[Sexually Transmitted Infections in the Tropics]. 61
30324430 2018
10
2018 UK national guideline for the management of donovanosis. 61
29743002 2018
11
Donovanosis in a child victim of sexual abuse: response to doxycycline treatment. 61
30066775 2018
12
Donovanosis in a child victim of sexual abuse: response to doxycycline treatment. 61
33288059 2018
13
Usefulness and Utility of NACO Regime in the Management of Sexually Transmitted Infections: A Pilot Study. 61
29263538 2017
14
Skin diseases of the vulva: Infectious diseases. 61
28397528 2017
15
Granulomatous & histiocytic dermatitides. 61
28094163 2017
16
Donovanosis and squamous cell carcinoma: The relationship conundrum! 61
27535727 2017
17
Donovanosis With Bowen Disease. 61
28270316 2017
18
Tuberculosis of Glans Penis- A Rare Presentation. 61
28208927 2016
19
[Donovanosis (granuloma inguinale)]. 61
27773509 2016
20
[A case of donovanosis acquired in France]. 61
27174716 2016
21
Other sexually transmitted diseases chancroid and donovanosis. 61
27107782 2016
22
Nonhealing genital ulcer in AIDS: A diagnostic dilemma! 61
27890958 2016
23
2016 European guideline on donovanosis. 61
26882914 2016
24
Granuloma inguinale in a 51-year-old man. 61
27617463 2016
25
Non-healing genital herpes mimicking donovanosis in an immunocompetent man. 61
25614521 2016
26
Medical Examination of Aliens--Revisions to Medical Screening Process. Final rule. 61
26812891 2016
27
Deep Fungal Infections, Blastomycosis-Like Pyoderma, and Granulomatous Sexually Transmitted Infections. 61
26143434 2015
28
Donovanosis causing lymphadenitis, mastoiditis, and meningitis in a child. 61
26122163 2015
29
Travel-related sexually transmitted infections. 61
26726895 2015
30
The use of trimethoprim and sulfamethoxazole (TMP-SMX) in dermatology. 61
26774630 2015
31
Tuberculosis of the Penis: A Review of the Literature. 61
26435877 2015
32
Squamous cell carcinoma complicating donovanosis not a thing of the past! 61
24554002 2014
33
Pyoderma gangrenosum masquerading as Donovanosis. 61
26396454 2014
34
Genital donovanosis with malignant transformation: An interesting case report. 61
26396449 2014
35
Sexually transmitted infections. 61
24889293 2014
36
Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. 61
24559566 2014
37
Granuloma inguinale mimicking as squamous cell carcinoma of penis. 61
24958990 2014
38
Sexually transmitted diseases. 61
23958358 2013
39
Donovanosis: An incidental finding on Pap test. 61
24130421 2013
40
Genital Ulcer Disease: How Worrisome Is It Today? A Status Report from New Delhi, India. 61
26316954 2013
41
Infantile donovanosis presenting as external auditory canal polyps: a diagnostic trap. 61
23169417 2012
42
Genital elephantiasis due to donovanosis: forgotten but not gone yet ... 61
23155109 2012
43
Hypertrophic donavanosis in a young pregnant woman. 61
22840941 2012
44
Diagnosis and management of genital ulcers. 61
22335265 2012
45
Cytomorphology of unusual infectious entities in the Pap test. 61
22919422 2012
46
Cutaneous metastases of rectal mucinous adenocarcinoma mimicking granuloma inguinale. 61
22975572 2012
47
On the evolution of the sexually transmitted bacteria Haemophilus ducreyi and Klebsiella granulomatis. 61
22239475 2011
48
Pattern of sexually transmitted infections in males in interior Sindh: a 10-year-study. 61
23272449 2011
49
A forgotten disease reminds itself with a rare complication. 61
21965857 2011
50
HIV screening in commercially insured patients screened or diagnosed with sexually transmitted diseases or blood-borne pathogens. 61
21336232 2011

Variations for Granuloma Inguinale

Expression for Granuloma Inguinale

Search GEO for disease gene expression data for Granuloma Inguinale.

Pathways for Granuloma Inguinale

GO Terms for Granuloma Inguinale

Cellular components related to Granuloma Inguinale according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integrator complex GO:0032039 8.62 CT45A5 CT45A3

Biological processes related to Granuloma Inguinale according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 snRNA 3'-end processing GO:0034472 8.62 CT45A5 CT45A3

Sources for Granuloma Inguinale

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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