MCID: GRN005
MIFTS: 30

Granuloma Inguinale

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Granuloma Inguinale

MalaCards integrated aliases for Granuloma Inguinale:

Name: Granuloma Inguinale 12 53 44 15 73
Donovanosis 12 53
Pudendal Ulcer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9113
ICD10 33 A58
ICD9CM 35 099.2
MeSH 44 D006100
NCIt 50 C3065
SNOMED-CT 68 28867007
UMLS 73 C0018190

Summaries for Granuloma Inguinale

Disease Ontology : 12 A primary bacterial infectious disease that results in infection located in skin or located in mucosa of genital tract, has material basis in Klebsiella granulomatis, transmitted by sexual contact or transmitted by contact with the open sores. The infection has symptom painless genital ulcers.

MalaCards based summary : Granuloma Inguinale, also known as donovanosis, is related to lymphogranuloma venereum and chancroid, and has symptoms including painless genital ulcers An important gene associated with Granuloma Inguinale is INVS (Inversin). The drug Adalimumab has been mentioned in the context of this disorder. Affiliated tissues include skin, cervix and bone.

Wikipedia : 76 Granuloma inguinale (also known as donovanosis) is a bacterial disease caused by Klebsiella granulomatis... more...

Related Diseases for Granuloma Inguinale

Diseases related to Granuloma Inguinale via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 26)
# Related Disease Score Top Affiliating Genes
1 lymphogranuloma venereum 29.6 CPN1 INVS QRSL1 RBM10 SLC44A1 ZP3
2 chancroid 10.6
3 squamous cell carcinoma 10.3
4 syphilis 10.2
5 otitis media 10.0
6 mastoiditis 10.0
7 osteomyelitis 10.0
8 lymphadenitis 10.0
9 vaginitis 10.0
10 adenocarcinoma 10.0
11 mucinous adenocarcinoma 10.0
12 elephantiasis 10.0
13 myoblastoma 10.0
14 human immunodeficiency virus infectious disease 10.0
15 penis squamous cell carcinoma 10.0
16 herpes simplex 10.0
17 genital herpes 10.0
18 molluscum contagiosum 10.0
19 splenomegaly 10.0
20 ovarian cancer 9.9
21 leukemia 9.9
22 hairy cell leukemia 9.9
23 pyoderma 9.9
24 pyoderma gangrenosum 9.9
25 meningitis 9.9
26 premature ovarian failure 1 9.8 WT1 ZP3

Graphical network of the top 20 diseases related to Granuloma Inguinale:



Diseases related to Granuloma Inguinale

Symptoms & Phenotypes for Granuloma Inguinale

Symptoms:

12
  • painless genital ulcers

Drugs & Therapeutics for Granuloma Inguinale

Drugs for Granuloma Inguinale (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Adalimumab Approved 331731-18-1 16219006

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation) Completed NCT01960790

Search NIH Clinical Center for Granuloma Inguinale

Cochrane evidence based reviews: granuloma inguinale

Genetic Tests for Granuloma Inguinale

Anatomical Context for Granuloma Inguinale

MalaCards organs/tissues related to Granuloma Inguinale:

41
Skin, Cervix, Bone, Testes, Lymph Node, Spinal Cord, Kidney

The Foundational Model of Anatomy Ontology organs/tissues related to Granuloma Inguinale:

19
Skin Or

Publications for Granuloma Inguinale

Articles related to Granuloma Inguinale:

(show top 50) (show all 372)
# Title Authors Year
1
2018 UK national guideline for the management of donovanosis. ( 29743002 )
2018
2
Donovanosis in a child victim of sexual abuse: response to doxycycline treatment. ( 30066775 )
2018
3
Donovanosis and squamous cell carcinoma: The relationship conundrum! ( 27535727 )
2017
4
Donovanosis With Bowen Disease. ( 28270316 )
2017
5
Granuloma inguinale in a 51-year-old man. ( 27617463 )
2016
6
2016 European guideline on donovanosis. ( 26882914 )
2016
7
Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. ( 24559566 )
2014
8
Granuloma inguinale mimicking as squamous cell carcinoma of penis. ( 24958990 )
2014
9
Pyoderma gangrenosum masquerading as Donovanosis. ( 26396454 )
2014
10
Squamous cell carcinoma complicating donovanosis not a thing of the past! ( 24554002 )
2014
11
Genital donovanosis with malignant transformation: An interesting case report. ( 26396449 )
2014
12
Donovanosis: An incidental finding on Pap test. ( 24130421 )
2013
13
Cutaneous metastases of rectal mucinous adenocarcinoma mimicking granuloma inguinale. ( 22975572 )
2012
14
Infantile donovanosis presenting as external auditory canal polyps: a diagnostic trap. ( 23169417 )
2012
15
Granuloma inguinale (Donovanosis). ( 21738983 )
2011
16
European guideline for the management of donovanosis, 2010. ( 21097731 )
2010
17
Donovanosis presenting as a pelvic mass mimicking ovarian cancer. ( 19077787 )
2009
18
Concomitant malacoplakia and granuloma inguinale of the cervix in acquired immune deficiency syndrome. ( 18317211 )
2008
19
Malignant transformation of donovanosis (granuloma inguinale) in a HIV-positive patient. ( 19061590 )
2008
20
Case report. MR appearance of cervical donovanosis mimicking carcinoma of the cervix. ( 18487384 )
2008
21
Donovanosis with auto-amputation of penis in a HIV-2 infected person. ( 19052412 )
2008
22
Donovanosis. ( 19287842 )
2008
23
Primary perianal perineo-crural postpederasty donovanosis. ( 17651172 )
2007
24
Donovanosis treated with thiamphenicol. ( 17873989 )
2007
25
Donovanosis (granuloma inguinale). ( 17151047 )
2006
26
Granuloma inguinale: a case report. ( 17459300 )
2006
27
Bilateral psoas abscess in a case of granuloma inguinale. ( 16459521 )
2005
28
Donovanosis in Australia: going, going... ( 16199732 )
2005
29
Donovanosis in developed countries: neglected or misdiagnosed disease? ( 12716504 )
2003
30
A clinical and investigational study of donovanosis. ( 17642866 )
2003
31
Disseminated donovanosis (granuloma inguinale) with osteomyelitis of both wrists. ( 12501553 )
2002
32
Donovanosis in India: declining fast? ( 11886617 )
2002
33
Donovanosis. ( 12473810 )
2002
34
Oral donovanosis. ( 12537743 )
2002
35
Trovofloxacin for the treatment of chronic granuloma inguinale. ( 11287695 )
2001
36
Donovanosis: an update. ( 11394976 )
2001
37
Transepithelial elimination of cutaneous vulval granuloma inguinale. ( 11100808 )
2000
38
Donovanosis causing cervical lymphadenopathy in a five-month-old boy. ( 10694010 )
2000
39
Granuloma inguinale (donovanosis) presenting as a neck mass in an infant. ( 10079347 )
1999
40
National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). ( 10616381 )
1999
41
Diagnostic polymerase chain reaction for donovanosis. ( 10452659 )
1999
42
Treating donovanosis. ( 10615749 )
1999
43
Missing the diagnosis of donovanosis in northern Australia. ( 10026679 )
1999
44
Intrapelvic donovanosis presenting as a psoas abscess in two patients. ( 10448352 )
1999
45
Donovanosis. ( 10450993 )
1999
46
Surgical treatment of granuloma inguinale. ( 9747380 )
1998
47
Disseminated donovanosis (granuloma inguinale) causing spinal cord compression: case report and review of donovanosis involving bone. ( 9502458 )
1998
48
Disseminated granuloma inguinale secondary to cervical infection. ( 9515686 )
1998
49
Clinico-epidemiologic features of granuloma inguinale in the era of acquired immune deficiency syndrome. ( 9564722 )
1998
50
Donovanosis: treatment with azithromycin. ( 9518024 )
1998

Variations for Granuloma Inguinale

Expression for Granuloma Inguinale

Search GEO for disease gene expression data for Granuloma Inguinale.

Pathways for Granuloma Inguinale

GO Terms for Granuloma Inguinale

Sources for Granuloma Inguinale

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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