MCID: GRN005
MIFTS: 33

Granuloma Inguinale

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Granuloma Inguinale

MalaCards integrated aliases for Granuloma Inguinale:

Name: Granuloma Inguinale 12 53 44 15 73
Donovanosis 12 53
Pudendal Ulcer 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9113
ICD10 33 A58
ICD9CM 35 099.2
MeSH 44 D006100
NCIt 50 C3065
SNOMED-CT 68 186947000 28867007
UMLS 73 C0018190

Summaries for Granuloma Inguinale

Disease Ontology : 12 A primary bacterial infectious disease that results in infection located in skin or located in mucosa of genital tract, has material basis in Klebsiella granulomatis, transmitted by sexual contact or transmitted by contact with the open sores. The infection has symptom painless genital ulcers.

MalaCards based summary : Granuloma Inguinale, also known as donovanosis, is related to lymphogranuloma venereum and chancroid, and has symptoms including painless genital ulcers An important gene associated with Granuloma Inguinale is WT1 (Wilms Tumor 1). The drug Adalimumab has been mentioned in the context of this disorder. Affiliated tissues include skin or, skin and cervix.

Wikipedia : 76 Granuloma inguinale (also known as donovanosis) is a bacterial disease caused by Klebsiella granulomatis... more...

Related Diseases for Granuloma Inguinale

Diseases related to Granuloma Inguinale via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 27)
# Related Disease Score Top Affiliating Genes
1 lymphogranuloma venereum 10.5
2 chancroid 10.5
3 squamous cell carcinoma 10.1
4 cervicitis 10.1
5 syphilis 10.1
6 vaginitis 10.0
7 otitis media 9.9
8 sinusitis 9.9
9 connective tissue benign neoplasm 9.9
10 mastoiditis 9.9
11 osteomyelitis 9.9
12 lymphadenitis 9.9
13 adenocarcinoma 9.9
14 mucinous adenocarcinoma 9.9
15 myoblastoma 9.9
16 penis squamous cell carcinoma 9.9
17 endocervicitis 9.9
18 herpes simplex 9.9
19 genital herpes 9.9
20 molluscum contagiosum 9.9
21 splenomegaly 9.9
22 iris disease 9.7 MRAP WT1
23 core binding factor acute myeloid leukemia 9.7 ABCG2 WT1
24 posterior scleritis 9.5 CD22 MRAP
25 anterior scleritis 9.3 CD22 MRAP
26 hematologic cancer 9.3 ABCG2 CD22 WT1
27 leukemia, acute myeloid 8.8 ABCG2 CD22 WT1

Graphical network of the top 20 diseases related to Granuloma Inguinale:



Diseases related to Granuloma Inguinale

Symptoms & Phenotypes for Granuloma Inguinale

Symptoms:

12
  • painless genital ulcers

Drugs & Therapeutics for Granuloma Inguinale

Drugs for Granuloma Inguinale (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Adalimumab Approved 331731-18-1 16219006

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Special Investigation in Patients With Intestinal Behcet's Disease (All Case Investigation) Completed NCT01960790

Search NIH Clinical Center for Granuloma Inguinale

Cochrane evidence based reviews: granuloma inguinale

Genetic Tests for Granuloma Inguinale

Anatomical Context for Granuloma Inguinale

The Foundational Model of Anatomy Ontology organs/tissues related to Granuloma Inguinale:

19
Skin Or

MalaCards organs/tissues related to Granuloma Inguinale:

41
Skin, Cervix, Bone, Testes, Lymph Node, Spinal Cord, Uterus

Publications for Granuloma Inguinale

Articles related to Granuloma Inguinale:

(show top 50) (show all 265)
# Title Authors Year
1
Granuloma inguinale in a 51-year-old man. ( 27617463 )
2016
2
Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum. ( 24559566 )
2014
3
Granuloma inguinale mimicking as squamous cell carcinoma of penis. ( 24958990 )
2014
4
Cutaneous metastases of rectal mucinous adenocarcinoma mimicking granuloma inguinale. ( 22975572 )
2012
5
Granuloma inguinale (Donovanosis). ( 21738983 )
2011
6
Concomitant malacoplakia and granuloma inguinale of the cervix in acquired immune deficiency syndrome. ( 18317211 )
2008
7
Malignant transformation of donovanosis (granuloma inguinale) in a HIV-positive patient. ( 19061590 )
2008
8
Donovanosis (granuloma inguinale). ( 17151047 )
2006
9
Granuloma inguinale: a case report. ( 17459300 )
2006
10
Bilateral psoas abscess in a case of granuloma inguinale. ( 16459521 )
2005
11
Disseminated donovanosis (granuloma inguinale) with osteomyelitis of both wrists. ( 12501553 )
2002
12
Trovofloxacin for the treatment of chronic granuloma inguinale. ( 11287695 )
2001
13
Transepithelial elimination of cutaneous vulval granuloma inguinale. ( 11100808 )
2000
14
Granuloma inguinale (donovanosis) presenting as a neck mass in an infant. ( 10079347 )
1999
15
National guideline for the management of donovanosis (granuloma inguinale). Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). ( 10616381 )
1999
16
Surgical treatment of granuloma inguinale. ( 9747380 )
1998
17
Disseminated donovanosis (granuloma inguinale) causing spinal cord compression: case report and review of donovanosis involving bone. ( 9502458 )
1998
18
Disseminated granuloma inguinale secondary to cervical infection. ( 9515686 )
1998
19
Clinico-epidemiologic features of granuloma inguinale in the era of acquired immune deficiency syndrome. ( 9564722 )
1998
20
Growth and cultural characteristics of Calymmatobacterium granulomatis--the aetiological agent of granuloma inguinale (Donovanosis). ( 9236742 )
1997
21
Granuloma inguinale (donovanosis): an unusual cause of otitis media and mastoiditis in children. ( 9353089 )
1997
22
Granuloma inguinale and HIV: a unique presentation and novel treatment regimen. ( 9308572 )
1997
23
Granuloma inguinale in association with pregnancy and HIV infection. ( 8735293 )
1996
24
Granuloma inguinale: self-assessment. ( 8642110 )
1996
25
Granuloma inguinale: first case reported in the last four decades in China. ( 8891837 )
1996
26
Laboratory techniques used in the diagnosis of chancroid, granuloma inguinale, and lymphogranuloma venereum. ( 8143374 )
1994
27
Mucocutaneous manifestations of chancroid, lymphogranuloma venereum and granuloma inguinale. ( 8304262 )
1994
28
Nongenital granuloma inguinale in an oncology patient. ( 8092122 )
1994
29
Granuloma inguinale (donovanosis) in women. An analysis of 61 cases from Durban, South Africa. ( 8511711 )
1993
30
Granuloma inguinale: three cases diagnosed in Toronto, Canada. ( 1399195 )
1992
31
Failure of single dose ceftriaxone in donovanosis (granuloma inguinale) ( 1582667 )
1992
32
Donovanosis (granuloma inguinale) still exists. ( 1634289 )
1992
33
A serological test for granuloma inguinale. ( 1398665 )
1992
34
HLA antigens in donovanosis (granuloma inguinale). ( 1743713 )
1991
35
The diagnosis and treatment of donovanosis (granuloma inguinale). ( 1774048 )
1991
36
Donovanosis (granuloma inguinale) in pregnancy. ( 1782239 )
1991
37
A rapid stain for the diagnosis of granuloma inguinale. ( 1712751 )
1991
38
Failure of single dose ceftriaxone in donovanosis (granuloma inguinale) ( 2071134 )
1991
39
The enigma of granuloma inguinale in South Africa. ( 2180091 )
1990
40
Granuloma inguinale of the cervix: a carcinoma look-alike. ( 2245986 )
1990
41
Diagnosis of an unusual abdominal presentation of granuloma inguinale by fine needle aspiration cytology. ( 2375227 )
1990
42
Failure of single dose spectinomycin in granuloma inguinale (donovanosis). ( 2151409 )
1990
43
HIV and granuloma inguinale in Durban. ( 2256986 )
1990
44
Extragenital granuloma inguinale mimicking a soft-tissue neoplasm: a case report and review of the literature. ( 1692564 )
1990
45
A rapid stain for the diagnosis of granuloma inguinale. ( 1695193 )
1990
46
Perianal abscess and sinuses caused by granuloma inguinale. Case report. ( 2618517 )
1989
47
Mutilating granuloma inguinale after rape. A case report. ( 2749430 )
1989
48
Lymphogranuloma venereum, chancroid, and granuloma inguinale. ( 2687744 )
1989
49
Chancroid and granuloma inguinale. ( 2676322 )
1989
50
A clinicopathological study of granuloma inguinale in Barbados. ( 3247729 )
1988

Variations for Granuloma Inguinale

Expression for Granuloma Inguinale

Search GEO for disease gene expression data for Granuloma Inguinale.

Pathways for Granuloma Inguinale

GO Terms for Granuloma Inguinale

Biological processes related to Granuloma Inguinale according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 male gonad development GO:0008584 8.62 RRM1 WT1

Sources for Granuloma Inguinale

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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