MCID: GRN001
MIFTS: 22

Granulomatous Endometritis

Categories: Reproductive diseases

Aliases & Classifications for Granulomatous Endometritis

MalaCards integrated aliases for Granulomatous Endometritis:

Name: Granulomatous Endometritis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4561
NCIt 50 C27626
UMLS 70 C1333876

Summaries for Granulomatous Endometritis

Disease Ontology : 12 An endometritis that is characterized by the presence of granulomas in the uterus.

MalaCards based summary : Granulomatous Endometritis is related to endometritis and cervical adenocarcinoma. An important gene associated with Granulomatous Endometritis is SDC1 (Syndecan 1), and among its related pathways/superpathways are Adhesion and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include uterus.

Related Diseases for Granulomatous Endometritis

Diseases related to Granulomatous Endometritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 144)
# Related Disease Score Top Affiliating Genes
1 endometritis 29.9 SDC1 PGR ESR1
2 cervical adenocarcinoma 10.0 ESR1 CEACAM5
3 syringoma 10.0 ESR1 CEACAM5
4 mucinous adenofibroma 10.0 ESR1 CEACAM5
5 cardiomyopathy, familial hypertrophic, 9 10.0 ESR1 CEACAM5
6 diverticulitis 10.0 SDC1 CEACAM5
7 leiomyoma 9.9 PGR ESR1
8 glassy cell carcinoma of the cervix 9.9 PGR ESR1
9 breast intraductal papillomatosis 9.9 PGR ESR1
10 intraductal papilloma 9.9 PGR ESR1
11 nipple carcinoma 9.9 PGR ESR1
12 bartholin's gland adenoma 9.9 PGR ESR1
13 bartholin's gland adenoid cystic carcinoma 9.9 PGR ESR1
14 uterine corpus adenosarcoma 9.9 PGR ESR1
15 adenosarcoma 9.9 PGR ESR1
16 bartholin's gland benign neoplasm 9.9 PGR ESR1
17 chronic tympanitis 9.9 PGR ESR1
18 vestibular gland benign neoplasm 9.9 PGR ESR1
19 vulvar syringoma 9.9 PGR ESR1
20 lung leiomyoma 9.9 PGR ESR1
21 adult type testicular granulosa cell tumor 9.9 PGR ESR1
22 breast scirrhous carcinoma 9.9 PGR ESR1
23 oncocytic breast carcinoma 9.9 PGR ESR1
24 cervical clear cell adenocarcinoma 9.9 PGR ESR1
25 ovarian seromucinous carcinoma 9.9 PGR ESR1
26 breast papillary carcinoma 9.9 PGR ESR1
27 papillary carcinoma 9.9 PGR ESR1
28 intravenous leiomyomatosis 9.9 PGR ESR1
29 leiomyomatosis 9.9 PGR ESR1
30 comedo carcinoma 9.9 PGR ESR1
31 breast adenoid cystic carcinoma 9.9 PGR ESR1
32 breast metaplastic carcinoma 9.9 PGR ESR1
33 intracranial meningioma 9.9 PGR ESR1
34 vulvar leiomyoma 9.9 PGR ESR1
35 bizarre leiomyoma 9.9 PGR ESR1
36 breast adenoma 9.9 PGR ESR1
37 lipid-rich carcinoma 9.9 PGR ESR1
38 breast malignant phyllodes tumor 9.9 PGR ESR1
39 prostate stromal sarcoma 9.9 PGR ESR1
40 progesterone-receptor negative breast cancer 9.9 PGR ESR1
41 breast osteosarcoma 9.9 PGR ESR1
42 apocrine adenocarcinoma 9.9 PGR ESR1
43 cervical adenosarcoma 9.9 PGR ESR1
44 breast neuroendocrine neoplasm 9.9 PGR ESR1
45 gender identity disorder 9.9 PGR ESR1
46 progesterone resistance 9.9 PGR ESR1
47 biphasic synovial sarcoma 9.9 PGR ESR1
48 intraductal breast benign neoplasm 9.9 PGR ESR1
49 synchronous bilateral breast carcinoma 9.9 PGR ESR1
50 cribriform carcinoma 9.9 PGR ESR1

Graphical network of the top 20 diseases related to Granulomatous Endometritis:



Diseases related to Granulomatous Endometritis

Symptoms & Phenotypes for Granulomatous Endometritis

Drugs & Therapeutics for Granulomatous Endometritis

Search Clinical Trials , NIH Clinical Center for Granulomatous Endometritis

Genetic Tests for Granulomatous Endometritis

Anatomical Context for Granulomatous Endometritis

MalaCards organs/tissues related to Granulomatous Endometritis:

40
Uterus

Publications for Granulomatous Endometritis

Articles related to Granulomatous Endometritis:

(show all 22)
# Title Authors PMID Year
1
Genital tuberculosis screening at an academic fertility center in the United States. 61
32497612 2020
2
Disseminated Tuberculosis Involving Lung, Peritoneum, and Endometrium in an Immunocompetent 17-Year-Old Patient. 61
32789033 2020
3
[Rare location of tuberculosis: endometrial tuberculosis]. 61
31448008 2019
4
[Endometritis : Rare disease with clinical importance?] 61
27738813 2016
5
Flare-up of genital tuberculosis following endometrial aspiration in a patient of generalized miliary tuberculosis. 61
19381667 2009
6
ER, PR and Ki-67 expression status in granulomatous and chronic non-specific endometritis. 61
18686353 2008
7
Detection of Mycobacterium tuberculosis DNA by polymerase chain reaction from paraffin samples of chronic granulomatous endometritis. 61
17880545 2007
8
Investigations on brucellosis in Egyptian Baladi Does with emphasis on evaluation of diagnostic techniques. 61
19070039 2007
9
Isolated endometrial polypoid sarcoidosis in a post-menopausal patient: case report. 61
16427748 2006
10
Endometrial coccidiosis. 61
15452171 2004
11
Post-hysteroscopic ablation reaction: a histopathologic study of the effects of electrosurgical ablation. 61
10542940 1999
12
Uterine surveillance of asymptomatic postmenopausal women taking tamoxifen. 61
11907942 1998
13
Elevation of carcinoembryonic antigen and CA-125 in a patient with multivisceral tuberculosis. 61
9046768 1997
14
Histopathological observations in new and classic models of experimental Schistosoma haematobium infections. 61
8673838 1996
15
Postoperative uterine granulomata following endometrial resection. 61
7567157 1995
16
Necrotising granulomatous endometritis following endometrial ablation therapy. 61
1450148 1992
17
Granulomatous endometritis associated with histologically occult cytomegalovirus in a healthy patient. 61
1326899 1992
18
Endometrial tuberculosis acquired by a health care worker in a clinical laboratory. 61
1580757 1992
19
Granulomatous endometritis following hysteroscopic resection of the endometrium. 61
2010187 1991
20
Coccidioidomycosis of the female genital tract. 61
3753858 1986
21
Pelvic tuberculosis. 61
819884 1976
22
[Granulomatous endometritis]. 61
5852938 1965

Variations for Granulomatous Endometritis

Expression for Granulomatous Endometritis

Search GEO for disease gene expression data for Granulomatous Endometritis.

Pathways for Granulomatous Endometritis

Pathways related to Granulomatous Endometritis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.35 SDC1 CEACAM5
2 11.22 SDC1 CEACAM5
3
Show member pathways
10.99 PGR ESR1
4
Show member pathways
10.58 PGR ESR1

GO Terms for Granulomatous Endometritis

Biological processes related to Granulomatous Endometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 steroid hormone mediated signaling pathway GO:0043401 8.96 PGR ESR1
2 intracellular steroid hormone receptor signaling pathway GO:0030518 8.62 PGR ESR1

Molecular functions related to Granulomatous Endometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.46 SDC1 PGR ESR1 CEACAM5
2 ATPase binding GO:0051117 9.32 PGR ESR1
3 nuclear receptor activity GO:0004879 9.26 PGR ESR1
4 steroid binding GO:0005496 8.96 PGR ESR1
5 steroid hormone receptor activity GO:0003707 8.62 PGR ESR1

Sources for Granulomatous Endometritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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