MCID: GRN033
MIFTS: 31

Granulomatous Mastitis

Categories: Reproductive diseases, Rare diseases

Aliases & Classifications for Granulomatous Mastitis

MalaCards integrated aliases for Granulomatous Mastitis:

Name: Granulomatous Mastitis 59 73
Idiopathic Granulomatous Mastitis 59

Classifications:



External Ids:

Orphanet 59 ORPHA64722
MESH via Orphanet 45 D058890
UMLS via Orphanet 74 C0405469
ICD10 via Orphanet 34 N61
UMLS 73 C0405469

Summaries for Granulomatous Mastitis

MalaCards based summary : Granulomatous Mastitis, also known as idiopathic granulomatous mastitis, is related to granulomatous lobular mastitis and mastitis. An important gene associated with Granulomatous Mastitis is IL33 (Interleukin 33), and among its related pathways/superpathways is Deubiquitination. The drugs Hydrocortisone and Histamine have been mentioned in the context of this disorder. Affiliated tissues include breast, neutrophil and pituitary.

Wikipedia : 76 Granulomatous mastitis can be divided into idiopathic granulomatous mastitis (also known as granular... more...

Related Diseases for Granulomatous Mastitis

Graphical network of the top 20 diseases related to Granulomatous Mastitis:



Diseases related to Granulomatous Mastitis

Symptoms & Phenotypes for Granulomatous Mastitis

Drugs & Therapeutics for Granulomatous Mastitis

Drugs for Granulomatous Mastitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Hydrocortisone Approved, Vet_approved Phase 4 50-23-7 5754
2
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774
3
Butyric Acid Experimental, Investigational Phase 4 107-92-6 264
4
Histamine Phosphate Phase 4 51-74-1 65513
5 Cortisol succinate Phase 4
6 Neurotransmitter Agents Phase 4
7 Histamine Antagonists Phase 4
8 Dermatologic Agents Phase 4
9 Hydrocortisone 17-butyrate 21-propionate Phase 4
10 Hydrocortisone acetate Phase 4
11 Hydrocortisone-17-butyrate Phase 4
12 Anti-Inflammatory Agents Phase 4
13
Methotrexate Approved 1959-05-2, 59-05-2 126941
14
Chlorhexidine Approved, Vet_approved 55-56-1 9552079 2713
15
Lidocaine Approved, Vet_approved 137-58-6 3676
16
Ceftriaxone Approved 73384-59-5 5479530 5361919
17
Triamcinolone Approved, Vet_approved 124-94-7 31307
18 Chlorhexidine gluconate
19 Contraceptive Agents
20 Contraceptives, Oral
21 Anti-Bacterial Agents
22 Antibiotics, Antitubercular
23 Immunosuppressive Agents
24 triamcinolone acetonide
25 Anesthetics
26 Triamcinolone diacetate
27 Triamcinolone hexacetonide
28 Pharmaceutical Solutions
29 Calamus Nutraceutical

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Medical and Surgical Treatment for Idiopathic Granulomatous Mastitis Recruiting NCT02959580 Phase 4 Hydrocortisone Butyrate
2 Granulomatous Mastitis Current Approach and Treatment Completed NCT02667132
3 Ductal Lavage in Non-lactating Female Women With Mastitis Active, not recruiting NCT02794688

Search NIH Clinical Center for Granulomatous Mastitis

Genetic Tests for Granulomatous Mastitis

Anatomical Context for Granulomatous Mastitis

MalaCards organs/tissues related to Granulomatous Mastitis:

41
Breast, Neutrophil, Pituitary

Publications for Granulomatous Mastitis

Articles related to Granulomatous Mastitis:

(show top 50) (show all 268)
# Title Authors Year
1
Idiopathic lobular granulomatous mastitis: radiological management in two cases. ( 29793678 )
2018
2
Scoring Idiopathic Granulomatous Mastitis: An Effective System for Predicting Recurrence? ( 29774320 )
2018
3
Idiopathic Granulomatous Mastitis: Manifestations at Multimodality Imaging and Pitfalls. ( 29528819 )
2018
4
Corynebacterium kroppenstedtii in granulomatous mastitis: Analysis of formalin-fixed, paraffin-embedded biopsy specimens by immunostaining using low-specificity bacterial antisera and real-time polymerase chain reaction. ( 29862601 )
2018
5
Is erythema nodosum coexisting with lesions of the breast a suggestive sign for idiopathic granulomatous mastitis? ( 29756114 )
2018
6
Diagnosis and Treatment of 75 Patients with Idiopathic Lobular Granulomatous Mastitis. ( 29381437 )
2018
7
Advantages of b-mode ultrasound combined with strain elastography in differentiation of idiopathic granulomatous mastitis from malignant breast lesions ( 29479939 )
2018
8
Granulomatous Mastitis Concurrence with Breast Cancer. ( 29322122 )
2018
9
Granulomatous mastitis: etiology, imaging, pathology, treatment, and clinical findings. ( 29971624 )
2018
10
Steroids administered after vacuum-assisted biopsy in the management of idiopathic granulomatous mastitis. ( 28931582 )
2017
11
Differentiation between idiopathic granulomatous mastitis and malignant breast lesions using strain ratio on ultrasonic elastography. ( 28729183 )
2017
12
Differential diagnosis of idiopathic granulomatous mastitis and breast cancer using acoustic radiation force impulse imaging. ( 27787642 )
2017
13
Cystic neutrophilic granulomatous mastitis associated with Corynebacterium including Corynebacterium kroppenstedtii. ( 28442140 )
2017
14
Clinical and Cytological Spectrum of Granulomatous Mastitis and Utility of FNAC in Picking up Tubercular Mastitis: An Eight-Year Study. ( 28511395 )
2017
15
Lymphoepithelioma-Like Carcinoma of the Breast Mimicking Granulomatous Mastitis- Case Report and Review of the Literature ( 28749097 )
2017
16
Follow-up of granulomatous mastitis with monitoring versus surgery. ( 28655119 )
2017
17
Risperidone Induced Granulomatous Mastitis Secondary to Hyperprolactinemia in a Non-Pregnant Woman-A Rare Case Report in a Bipolar Disorder. ( 28273980 )
2017
18
Erythema nodosum in association with idiopathic granulomatous mastitis: a case series and review of the literature. ( 28271562 )
2017
19
Magnetic resonance imaging characteristics of granulomatous mastitis. ( 28364724 )
2017
20
Granulomatous Mastitis in a Transgender Patient. ( 28580069 )
2017
21
Mycophenolate mofetil as a successful therapy for idiopathic granulomatous mastitis. ( 29469699 )
2017
22
Idiopathic Granulomatous Mastitis: A Clinical Puzzle in Breast Lump Cases. ( 28764247 )
2017
23
Idiopathic granulomatous mastitis: dilemmas in diagnosis and treatment. ( 29038724 )
2017
24
Idiopathic granulomatous mastitis. A rare benign entitiy that can simulate breast cancer. ( 28733047 )
2017
25
Idiopathic granulomatous mastitis: A diagnostic and therapeutic challenge. ( 28739122 )
2017
26
Is idiopathic granulomatous mastitis a surgical disease? The jury is still out. ( 28856149 )
2017
27
Idiopathic granulomatous mastitis associated with hyperprolactinemia: A nonoperative approach. ( 28845595 )
2017
28
Treatments for Idiopathic Granulomatous Mastitis: Systematic Review and Meta-Analysis. ( 28731822 )
2017
29
Factors related to recurrence of idiopathic granulomatous mastitis: what do we learn from a multicentre study? ( 28749045 )
2017
30
Idiopathic granulomatous mastitis: an institutional experience. ( 28740959 )
2017
31
Granulomatous mastitis: We need a useful classification system. ( 28864358 )
2017
32
Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis. ( 28321344 )
2017
33
Coexistence of idiopathic granulomatous mastitis and erythemanodosum: successful treatment with corticosteroids ( 29151337 )
2017
34
The enigma of granulomatous mastitis: A series. ( 29081405 )
2017
35
Idiopathic Granulomatous Mastitis Associated with Erythema Nodosum. ( 27403395 )
2016
36
Magnetic Resonance Imaging Features of Idiopathic Granulomatous Mastitis: A Retrospective Analysis. ( 27853486 )
2016
37
Magnetic resonance imaging features of idiopathic granulomatous mastitis: is there any contribution of diffusion-weighted imaging in the differential diagnosis? ( 27406630 )
2016
38
Granulomatous Mastitis - More data is needed. ( 26778248 )
2016
39
Reply to "Granulomatous Mastitis - More data is needed". ( 26832944 )
2016
40
Association between Hyperprolactinemia and Granulomatous Mastitis. ( 26705962 )
2016
41
Etiologic revelation and outcome of the surgical management of idiopathic granulomatous mastitis; An Egyptian centre experience. ( 27612044 )
2016
42
A case of idiopathic granulomatous mastitis associated with erythema nodosum, arthritis, and reactive cough. ( 27051851 )
2016
43
Imaging features of idiopathic granulomatous mastitis - Case report. ( 27437673 )
2016
44
Idiopathic granulomatous mastitis: a diagnostic dilemma for the breast radiologist. ( 27164916 )
2016
45
Idiopathic granulomatous mastitis: imaging update and review. ( 27221974 )
2016
46
A variety of gene polymorphisms associated with idiopathic granulomatous mastitis. ( 27619324 )
2016
47
Chronic Mastitis in Egypt and Morocco: Differentiating between Idiopathic Granulomatous Mastitis and IgG4-Related Disease. ( 27279578 )
2016
48
Granulomatous Mastitis: Time to Introduce New Weapons. ( 26920409 )
2016
49
Granulomatous Mastitis: Imaging of Temporal Evolution. ( 27051554 )
2016
50
The Brief Case: Recurrent Granulomatous Mastitis Due to Corynebacterium kroppenstedtii. ( 27458268 )
2016

Variations for Granulomatous Mastitis

Expression for Granulomatous Mastitis

Search GEO for disease gene expression data for Granulomatous Mastitis.

Pathways for Granulomatous Mastitis

Pathways related to Granulomatous Mastitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.34 IL33 NOD2

GO Terms for Granulomatous Mastitis

Biological processes related to Granulomatous Mastitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein deubiquitination GO:0016579 9.16 IL33 NOD2
2 positive regulation of interleukin-6 production GO:0032755 8.96 IL33 NOD2
3 positive regulation of type 2 immune response GO:0002830 8.62 IL33 NOD2

Sources for Granulomatous Mastitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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