MCID: GRN036
MIFTS: 22

Granulomatous Myositis

Categories: Muscle diseases

Aliases & Classifications for Granulomatous Myositis

MalaCards integrated aliases for Granulomatous Myositis:

Name: Granulomatous Myositis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:3428
NCIt 49 C27575
UMLS 71 C1334150

Summaries for Granulomatous Myositis

MalaCards based summary : Granulomatous Myositis is related to myocarditis and pancytopenia. An important gene associated with Granulomatous Myositis is SCYL1 (SCY1 Like Pseudokinase 1). Affiliated tissues include t cells, skeletal muscle and skin, and related phenotypes are hematopoietic system and immune system

Related Diseases for Granulomatous Myositis

Diseases related to Granulomatous Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 136)
# Related Disease Score Top Affiliating Genes
1 myocarditis 29.6 PIK3C2A CD68 ACE
2 pancytopenia 29.0 CD8A CD68 ACE
3 temporal arteritis 28.5 PRTN3 CD8A
4 exanthem 28.0 TRIM21 PRTN3 PIK3C2A CD8A ACE
5 myositis 10.7
6 sarcoidosis 1 10.4
7 acute anterolateral myocardial infarction 10.3 PIK3C2A ACE
8 toxic myocarditis 10.3 PIK3C2A ACE
9 acute mountain sickness 10.2 PIK3C2A ACE
10 pseudohyperkalemia, familial, 2, due to red cell leak 10.2 PIK3C2A ACE
11 myopathy 10.2
12 left bundle branch hemiblock 10.2 PIK3C2A ACE
13 anuria 10.2 PIK3C2A ACE
14 cardiac tamponade 10.2 PIK3C2A ACE
15 acute kidney tubular necrosis 10.2 PIK3C2A ACE
16 virus associated hemophagocytic syndrome 10.2 PIK3C2A CD68
17 aspiration pneumonia 10.2 PIK3C2A ACE
18 mitral valve insufficiency 10.2 PIK3C2A ACE
19 angina pectoris 10.2 PIK3C2A ACE
20 subacute cutaneous lupus erythematosus 10.2 TRIM21 ACE
21 myasthenia gravis 10.1
22 thymoma, familial 10.1
23 thymoma 10.1
24 intermediate coronary syndrome 10.1 PIK3C2A ACE
25 chronic dacryoadenitis 10.1 SCYL1 PRTN3
26 childhood type dermatomyositis 10.1 TRIM21 PIK3C2A
27 granulomatous dermatitis 10.1 CD68 ACE
28 cat-scratch disease 10.1 CD68 ACE
29 diffuse scleroderma 10.1 TRIM21 ACE
30 orbital plasma cell granuloma 10.1 PRTN3 PIK3C2A
31 pleural lipoma 10.1 PRTN3 PIK3C2A
32 third-degree atrioventricular block 10.1 TRIM21 ACE
33 pericardial effusion 10.1 PIK3C2A ACE
34 raynaud disease 10.1 TRIM21 ACE
35 vasculitis 10.1
36 polymyositis 10.1
37 dysphagia 10.1
38 posterior scleritis 10.1 PRTN3 ACE
39 tolosa-hunt syndrome 10.1 PRTN3 ACE
40 multiple cranial nerve palsy 10.1 PRTN3 ACE
41 cranial nerve palsy 10.1 PRTN3 ACE
42 granulomatous angiitis 10.1 PRTN3 ACE
43 cholesterol embolism 10.1 PRTN3 ACE
44 pericarditis 10.0 PIK3C2A ACE
45 scleral disease 10.0 PRTN3 ACE
46 hypersensitivity vasculitis 10.0 PRTN3 ACE
47 inclusion body myositis 10.0
48 endometrial cancer 10.0
49 inflammatory bowel disease 10.0
50 anaplastic large cell lymphoma 10.0

Graphical network of the top 20 diseases related to Granulomatous Myositis:



Diseases related to Granulomatous Myositis

Symptoms & Phenotypes for Granulomatous Myositis

MGI Mouse Phenotypes related to Granulomatous Myositis:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.56 ACE CD68 CD8A NHP2 PIK3C2A PRTN3
2 immune system MP:0005387 9.17 ACE CD68 CD8A PIK3C2A PRTN3 SCYL1

Drugs & Therapeutics for Granulomatous Myositis

Search Clinical Trials , NIH Clinical Center for Granulomatous Myositis

Genetic Tests for Granulomatous Myositis

Anatomical Context for Granulomatous Myositis

MalaCards organs/tissues related to Granulomatous Myositis:

40
T Cells, Skeletal Muscle, Skin, Tongue

Publications for Granulomatous Myositis

Articles related to Granulomatous Myositis:

(show top 50) (show all 81)
# Title Authors PMID Year
1
Atypical Multibacterial Granulomatous Myositis in a Horse: First Report in Italy. 61
32326275 2020
2
Granulomatous Myositis Associated with Extremely Elevated Anti-striated Muscle Antibodies in the Absence of Myasthenia Gravis. 61
32201659 2020
3
Granulomatous Myositis Showing Fluctuating "Leopard-Man" Sign: A Case Report on FDG PET/CT Imaging. 61
31689277 2019
4
Granulomatous Myositis Showing Fluctuating "Leopard-Man" Sign: A Case Report on FDG PET/CT Imaging. 61
31693623 2019
5
Granulomatous Myositis Associated with Myasthenia Gravis: A Rare Case. 61
31516798 2019
6
[Pig-slaughtering at home. Customs do not change. An infectological case report from a historical point of view]. 61
31433234 2019
7
Extranodal NK/T-cell Lymphoma Mimicking Granulomatous Myositis. 61
30146568 2019
8
Immunoglobulin (Ig)G-4 related myositis - A new entity? 61
30578098 2019
9
High prevalence of chigger mite infection in a forest-specialist frog with evidence of parasite-related granulomatous myositis. 61
29502295 2018
10
Symptomatic muscular sarcoidosis: Lessons from a nationwide multicenter study. 61
29845092 2018
11
A Rare Case of Sarcoidosis Presenting as Diffuse Contracturing Granulomatous Myositis on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography. 61
29643679 2018
12
Inflammatory myopathy associated with anti-mitochondrial antibodies: A distinct phenotype with cardiac involvement. 61
28893408 2018
13
Hypercalcemia revealing diffuse granulomatous myositis. 61
28396910 2017
14
Non-granulomatous myositis in a patient with ulcerative colitis who showed symptoms resembling gastrocnemius myalgia syndrome. 61
28132973 2017
15
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent. 61
27832822 2016
16
Sporadic inclusion body myositis misdiagnosed as idiopathic granulomatous myositis. 61
27692540 2016
17
A case of late-onset, thymoma-associated myasthenia gravis with ryanodine receptor and titin antibodies and concomitant granulomatous myositis. 61
27623618 2016
18
Characterization of Seven Outbreaks of Hemorrhagic Hepatopathy Syndrome in Commercial Pullets Following the Administration of a Salmonella Enteritidis Bacterin in California. 61
26953941 2016
19
Life-Threatening Hypercalcemia Revealing Diffuse and Isolated Acute Sarcoid-Like Myositis: A New Entity? (A Case-Series). 61
26962842 2016
20
LETTER TO THE EDITOR Atypical Granulomatous Myositis and Pulmonary Sarcoidosis. 61
26312107 2015
21
[Granulomatous myositis and cardiac dysfunction]. 61
23726749 2014
22
Diagnosis and classification of granulomatous myositis. 61
24424169 2014
23
Readability and histological biocompatibility of microchip transponders in horses. 61
23769456 2013
24
Granulomatous myositis associated with a novel alveolate pathogen in an adult southern leopard frog (Lithobates sphenocephalus). 61
23269391 2012
25
A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis. 61
22519739 2012
26
A case of severe 1,25-dihydroxyvitamin D-mediated hypercalcemia due to a granulomatous disorder. 61
22639294 2012
27
Granulomatous myositis associated with brucellosis: a case report and literature review. 61
22246889 2012
28
Distal muscle involvement in granulomatous myositis can mimic inclusion body myositis. 61
20562458 2011
29
Entamoeba invadens myositis in a common water monitor lizard (Varanus salvator). 61
19276058 2009
30
Paediatric contracturing granulomatous myositis. 61
18821276 2008
31
Granulomatous myositis mimicking slowly progressive lower motor neuron disease. 61
18700190 2008
32
[Diagnosis and differential diagnosis of granulomatous myositis]. 61
18210045 2008
33
Myopathology of non-infectious inflammatory myopathies - the current status. 61
18514433 2008
34
Apical ballooning (Takotsubo syndrome) in mitochondrial disorder during mechanical ventilation. 61
17885529 2007
35
Granulomatous myositis in association with chronic graft vs. host disease. 61
17970330 2007
36
[Sarcoidosis demonstrated by fluorodeoxyglucose positron emission tomography in a case of granulomatous myopathy]. 61
17445952 2007
37
Granulomatous myositis: a clinical study of thirteen cases. 61
17068767 2007
38
Consequences of misdiagnosing mitochondrial disorder. 61
16861155 2006
39
An autopsy case of aggressive CD30+ extra-nodal NK/T-cell lymphoma initially manifested with granulomatous myositis. 61
16321870 2006
40
Suppurative granulomatous myositis of an extra-ocular muscle in Crohn's disease. 61
16128967 2005
41
Clinical muscular sarcocystosis in a dog. 61
15856899 2005
42
Myositis, lameness, and recumbency after use of water-in-oil adjuvanted vaccines in near-term beef cattle. 61
15690947 2005
43
Localised gastrocnemius myositis in Crohn's disease. 61
12740681 2003
44
Granulomatous myositis associated with antithyroglobulin and antithyroid peroxidase antibodies: an analogy to Hashimoto's encephalitis? 61
12532931 2002
45
Granulomatous myositis: a manifestation of chronic graft-versus-host disease. 61
11904691 2002
46
Uptake of Ga-67 in granulomatous myositis with magnetic resonance imaging correlation. 61
11564935 2001
47
Skin ulcers in estuarine fishes: a comparative pathological evaluation of wild and laboratory-exposed fish. 61
11677176 2001
48
Granulomatous myositis, primary biliary cirrhosis, pancytopenia, and thymoma. 61
10883012 2000
49
[Involvement of the peripheral nervous system in Crohn disease]. 61
10637818 1999
50
Nodular sarcoid myositis of skeletal muscle diagnosed by fine needle aspiration biopsy. A case report. 61
10579000 1999

Variations for Granulomatous Myositis

Expression for Granulomatous Myositis

Search GEO for disease gene expression data for Granulomatous Myositis.

Pathways for Granulomatous Myositis

GO Terms for Granulomatous Myositis

Cellular components related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane raft GO:0044853 8.62 PRTN3 CD8A

Biological processes related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of autophagy GO:0010508 8.62 TRIM21 PIK3C2A

Sources for Granulomatous Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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