MCID: GRN036
MIFTS: 25

Granulomatous Myositis

Categories: Muscle diseases

Aliases & Classifications for Granulomatous Myositis

MalaCards integrated aliases for Granulomatous Myositis:

Name: Granulomatous Myositis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:3428
NCIt 51 C27575
UMLS 74 C1334150

Summaries for Granulomatous Myositis

MalaCards based summary : Granulomatous Myositis is related to myositis and sarcoidosis 1. An important gene associated with Granulomatous Myositis is TTN (Titin), and among its related pathways/superpathways are NF-kappaB Signaling and Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway. Affiliated tissues include t cells, tongue and lung, and related phenotypes are hematopoietic system and immune system

Related Diseases for Granulomatous Myositis

Diseases related to Granulomatous Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 73)
# Related Disease Score Top Affiliating Genes
1 myositis 31.0 NCAM1 PIK3C2A TTN
2 sarcoidosis 1 29.6 CD68 TNFRSF1B TNFRSF8
3 asphyxia neonatorum 10.3 PIK3C2A TTN
4 angiomyoma 10.2 NCAM1 PTHLH
5 virus associated hemophagocytic syndrome 10.2 CD68 PIK3C2A
6 fiedler's myocarditis 10.2 CD68 PIK3C2A
7 liver sarcoma 10.1 CD68 PTHLH
8 parasitic ichthyosporea infectious disease 10.1 CD68 NCAM1
9 rhinosporidiosis 10.1 CD68 NCAM1
10 hemangioma of intra-abdominal structure 10.1 CD68 PTHLH
11 large cell carcinoma 10.1 NCAM1 PTHLH
12 aleukemic leukemia cutis 10.1 CD68 NCAM1
13 erythema elevatum diutinum 10.1 CD68 TNFRSF1B
14 acute salpingitis 10.1 CD68 TNFRSF1B
15 lymphoma 10.1
16 melkersson-rosenthal syndrome 10.0 CD68 TNFRSF1B
17 granulomatous gastritis 10.0 CD68 PRTN3
18 transient arthritis 10.0 PRTN3 TNFRSF1B
19 orbital plasma cell granuloma 10.0 NCAM1 PIK3C2A TNFRSF1B
20 inclusion body myositis 10.0
21 thymoma, familial 10.0
22 colitis 10.0
23 thymoma 10.0
24 granulomatous angiitis 10.0 CD68 PRTN3
25 palindromic rheumatism 10.0 PRTN3 TNFRSF1B
26 bone inflammation disease 9.9 PRTN3 TNFRSF1B
27 sternum cancer 9.9 CD68 TNFRSF8
28 pediatric lymphoma 9.9 NCAM1 TNFRSF8
29 pericoronitis 9.9 CD68 NCAM1 TNFRSF1B
30 conventional fibrosarcoma 9.9 CD68 TNFRSF8
31 rhinoscleroma 9.9 CD68 NCAM1 TNFRSF1B
32 lichen nitidus 9.9 CD68 TNFRSF8
33 lung lymphoma 9.9 NCAM1 TNFRSF8
34 hodgkin's lymphoma, lymphocytic depletion 9.9 CD68 TNFRSF8
35 t-cell/histiocyte rich large b cell lymphoma 9.9 CD68 TNFRSF8
36 lymphatic system cancer 9.9 NCAM1 TNFRSF8
37 reticulohistiocytic granuloma 9.9 CD68 TNFRSF8
38 leukocyte disease 9.8 NCAM1 TNFRSF8
39 anterior scleritis 9.8 NCAM1 PRTN3 TNFRSF1B
40 biliary cirrhosis, primary, 1 9.8
41 temporal arteritis 9.8
42 myasthenia gravis 9.8
43 neuronopathy, distal hereditary motor, type viib 9.8
44 graft-versus-host disease 9.8
45 anaplastic large cell lymphoma 9.8
46 arthritis 9.8
47 crohn's disease 9.8
48 motor neuron disease 9.8
49 primary biliary cirrhosis 9.8
50 pulmonary sarcoidosis 9.8

Graphical network of the top 20 diseases related to Granulomatous Myositis:



Diseases related to Granulomatous Myositis

Symptoms & Phenotypes for Granulomatous Myositis

MGI Mouse Phenotypes related to Granulomatous Myositis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.43 CD68 PIK3C2A PRTN3 PTHLH TNFRSF1B TNFRSF8
2 immune system MP:0005387 9.17 CD68 PIK3C2A PRTN3 PTHLH TNFRSF1B TNFRSF8

Drugs & Therapeutics for Granulomatous Myositis

Search Clinical Trials , NIH Clinical Center for Granulomatous Myositis

Genetic Tests for Granulomatous Myositis

Anatomical Context for Granulomatous Myositis

MalaCards organs/tissues related to Granulomatous Myositis:

42
T Cells, Tongue, Lung, Liver, Bone, B Cells

Publications for Granulomatous Myositis

Articles related to Granulomatous Myositis:

(show all 35)
# Title Authors Year
1
Extranodal NK/T-cell Lymphoma Mimicking Granulomatous Myositis. ( 30146568 )
2019
2
High prevalence of chigger mite infection in a forest-specialist frog with evidence of parasite-related granulomatous myositis. ( 29502295 )
2018
3
A Rare Case of Sarcoidosis Presenting as Diffuse Contracturing Granulomatous Myositis on Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography. ( 29643679 )
2018
4
Hypercalcemia revealing diffuse granulomatous myositis. ( 28396910 )
2017
5
Non-granulomatous myositis in a patient with ulcerative colitis who showed symptoms resembling gastrocnemius myalgia syndrome. ( 28132973 )
2017
6
A case of late-onset, thymoma-associated myasthenia gravis with ryanodine receptor and titin antibodies and concomitant granulomatous myositis. ( 27623618 )
2016
7
Sporadic inclusion body myositis misdiagnosed as idiopathic granulomatous myositis. ( 27692540 )
2016
8
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent. ( 27832822 )
2016
9
LETTER TO THE EDITOR Atypical Granulomatous Myositis and Pulmonary Sarcoidosis. ( 26312107 )
2015
10
Diagnosis and classification of granulomatous myositis. ( 24424169 )
2014
11
A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis. ( 22519739 )
2012
12
Granulomatous myositis associated with brucellosis: a case report and literature review. ( 22246889 )
2012
13
Granulomatous myositis associated with a novel alveolate pathogen in an adult southern leopard frog (Lithobates sphenocephalus). ( 23269391 )
2012
14
Distal muscle involvement in granulomatous myositis can mimic inclusion body myositis. ( 20562458 )
2011
15
Granulomatous myositis mimicking slowly progressive lower motor neuron disease. ( 18700190 )
2008
16
Paediatric contracturing granulomatous myositis. ( 18821276 )
2008
17
Granulomatous myositis: a clinical study of thirteen cases. ( 17068767 )
2007
18
Granulomatous myositis in association with chronic graft vs. host disease. ( 17970330 )
2007
19
An autopsy case of aggressive CD30+ extra-nodal NK/T-cell lymphoma initially manifested with granulomatous myositis. ( 16321870 )
2006
20
Suppurative granulomatous myositis of an extra-ocular muscle in Crohn's disease. ( 16128967 )
2005
21
Granulomatous myositis: a manifestation of chronic graft-versus-host disease. ( 11904691 )
2002
22
Granulomatous myositis associated with antithyroglobulin and antithyroid peroxidase antibodies: an analogy to Hashimoto's encephalitis? ( 12532931 )
2002
23
Uptake of Ga-67 in granulomatous myositis with magnetic resonance imaging correlation. ( 11564935 )
2001
24
Granulomatous myositis, primary biliary cirrhosis, pancytopenia, and thymoma. ( 10883012 )
2000
25
Granulomatous myositis. Clinicopathologic study of 12 cases. ( 10396287 )
1999
26
Idiopathic granulomatous myositis: does the clinical spectrum include polymyalgia rheumatica? ( 18639165 )
1999
27
Granulomatous myositis: pathologic re-evaluation by immunohistochemical analysis of infiltrating mononuclear cells. ( 9073027 )
1997
28
Tongue involvement in a patient with granulomatous myositis. ( 9305307 )
1997
29
Case report: MR features of granulomatous myositis. ( 9366543 )
1997
30
Contracturing granulomatous myositis: a separate entity. ( 2283532 )
1990
31
Sporotrichal arthritis presenting as granulomatous myositis. ( 4084333 )
1985
32
Granulomatous myositis in association with Sarcocystis sp. infection in wild ducks. ( 6808984 )
1982
33
[Granulomatous myositis during collagenosis (one case) and suprasellar dysgerminoma (one case) (author's transl)]. ( 482759 )
1979
34
Granulomatous myositis and myopathy associated with crohn's colitis. ( 958278 )
1976
35
Dysphagia due to granulomatous myositis of the cricopharyngeus muscle; physiological and cineradiographic studies prior to and following successful surgical therapy. ( 13912620 )
1961

Variations for Granulomatous Myositis

Expression for Granulomatous Myositis

Search GEO for disease gene expression data for Granulomatous Myositis.

Pathways for Granulomatous Myositis

Pathways related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.65 NCAM1 TNFRSF1B TNFRSF8
2
Show member pathways
11.02 TNFRSF1B TNFRSF8
3 10.1 TNFRSF1B TNFRSF8

GO Terms for Granulomatous Myositis

Biological processes related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-mediated signaling pathway GO:0033209 8.62 TNFRSF1B TNFRSF8

Sources for Granulomatous Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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