GRD2
MCID: GRV009
MIFTS: 15

Graves Disease 2 (GRD2)

Categories: Endocrine diseases, Immune diseases, Rare diseases

Aliases & Classifications for Graves Disease 2

MalaCards integrated aliases for Graves Disease 2:

Name: Graves Disease 2 56
Graves Disease, Susceptibility to, 2 56 13
Grd2 56

Classifications:



External Ids:

OMIM 56 603388

Summaries for Graves Disease 2

MalaCards based summary : Graves Disease 2, also known as graves disease, susceptibility to, 2, is related to sarcoma and graves' disease. An important gene associated with Graves Disease 2 is GRD2 (Graves Disease, Susceptibility To, 2). Affiliated tissues include thyroid, eye and breast.

More information from OMIM: 603388

Related Diseases for Graves Disease 2

Diseases in the Graves' Disease family:

Graves Disease 1 Graves Disease 2

Diseases related to Graves Disease 2 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 sarcoma 9.8
2 graves' disease 9.8
3 spindle cell sarcoma 9.8

Symptoms & Phenotypes for Graves Disease 2

Clinical features from OMIM:

603388

Drugs & Therapeutics for Graves Disease 2

Search Clinical Trials , NIH Clinical Center for Graves Disease 2

Genetic Tests for Graves Disease 2

Anatomical Context for Graves Disease 2

MalaCards organs/tissues related to Graves Disease 2:

40
Thyroid, Eye, Breast

Publications for Graves Disease 2

Articles related to Graves Disease 2:

(show all 40)
# Title Authors PMID Year
1
Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families. 56
12973666 2003
2
Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: evidence for genetic heterogeneity and gene interactions. 56
10599734 1999
3
Further evidence for a susceptibility locus on chromosome 20q13.11 in families with dominant transmission of Graves disease. 56
10521315 1999
4
A new Graves disease-susceptibility locus maps to chromosome 20q11.2. International Consortium for the Genetics of Autoimmune Thyroid Disease. 56
9837828 1998
5
A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. 56
9843983 1998
6
Surgical management of primary hyperparathyroidism. 61
29038858 2017
7
Management of Childhood Thyroid Nodules: Surgical and Endocrinological Findings in a Large Group of Cases. 61
28387647 2017
8
Clinical Value of Thyrotropin Receptor Antibodies for the Differential Diagnosis of Interferon Induced Thyroiditis. 61
26575116 2016
9
Significant role of serum CRP in differentiating inflammatory from non-inflammatory causes of thyrotoxicosis. 61
23226645 2012
10
Autoimmune thyroid disease in children and adolescents with idiopathic pulmonary arterial hypertension. 61
20009390 2010
11
Total thyroidectomy for benign disease in the pediatric patient--feasible and safe. 61
19635300 2009
12
Incidental thyroid carcinoma in patients with Graves' disease. 61
18206132 2008
13
Coeliac disease in Dutch patients with Hashimoto's thyroiditis and vice versa. 61
17461476 2007
14
[Development of neonatal Graves' disease--prediction, prevention and treatment]. 61
17154096 2006
15
Benign thyroid disease: what is the role of nuclear medicine? 61
16762609 2006
16
[Ghrelin expression in the tissues of different thyroid diseases]. 61
16617365 2006
17
Autoimmune diabetes mellitus, Hodgkin's disease and Graves' ophthalmopathy in a patient with 8.1 ancestral haplotype. 61
15002059 2004
18
Interleukin-13 gene polymorphisms in patients with Graves' disease. 61
14510917 2003
19
Anti-transglutaminase antibodies and the serological diagnosis of coeliac disease. 61
12680625 2003
20
Purine metabolism in leukocytes and erythrocytes in Graves' or Hashimoto's disease. 61
12489570 2002
21
The role of octreoscan in thyroid eye disease. 61
10229898 1999
22
Thyrotoxicosis: clinical and laboratory assessment. 61
10509130 1999
23
Relationship between breast cancer and thyroid disease: relevance of autoimmune thyroid disorders in breast malignancy. 61
8772562 1996
24
[CD26/dipeptidyl peptidase IV and thyroid peroxidase as molecular markers for differentiated thyroid carcinoma]. 61
8691639 1996
25
c-Kit proto-oncogene is more likely to lose expression in differentiated thyroid carcinoma than three thyroid-specific genes: thyroid peroxidase, thyroglobulin, and thyroid stimulating hormone receptor. 61
8574299 1995
26
Congenital thyroid hemiagenesis. 61
7793746 1995
27
[Hyperthyroidism and cancer of the thyroid]. 61
7970050 1994
28
Isolation of thyroid peroxidase from patients with Graves' disease and comparison with animal peroxidases. 61
8187932 1994
29
Expression levels of the thyrotropin receptor gene in autoimmune thyroid disease: coregulation with parameters of thyroid function and inverse relation to major histocompatibility complex classes I and II. 61
8496329 1993
30
Is TPO detectable in the circulation? 61
8257863 1993
31
[Change in serum G-CSF levels in patients with Graves' disease by treatment with methimazole]. 61
1281122 1992
32
TSH-receptor and adhesion molecules in autoimmune thyroid disease. 61
1468511 1992
33
[Comparison of ultrasound, computed tomography and magnetic resonance imaging in diagnosis of orbital disorders]. 61
1815923 1991
34
Linkage of HLA-DR beta specific restriction fragment length polymorphisms with Graves' disease. 61
2902722 1988
35
Abnormal thyrotropin-binding immunoglobulins in two patients with Graves' disease. 61
6145722 1984
36
Evaluating the usefulness in neuro-ophthalmology of visual field examinations peripheral to 30 degrees. 61
6442949 1984
37
Coexpression of multiple immunoglobulin isotypes on human B-lymphocytes. 61
6440855 1984
38
Rapid improvement of thyroid function by using glucocorticoid indicated for the preoperative preparation of subtotal thyroidectomy in Graves' disease. 61
6688394 1983
39
[The 20-minute iodine uptake in Graves' disease. 2. Natural course during medical treatment (author's transl)]. 61
6895290 1981
40
Thyroid-stimulating antibodies in patients with autoimmune disorders. 61
263731 1978

Variations for Graves Disease 2

Expression for Graves Disease 2

Search GEO for disease gene expression data for Graves Disease 2.

Pathways for Graves Disease 2

GO Terms for Graves Disease 2

Sources for Graves Disease 2

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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