MCID: GMC001
MIFTS: 18

Gum Cancer

Categories: Cancer diseases, Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Gum Cancer

MalaCards integrated aliases for Gum Cancer:

Name: Gum Cancer 12 15
Malignant Tumor of Gum 12 73
Malignant Neoplasm of Other Sites of Gum 12
Malignant Tumour of Gingiva 12
Malignant Neoplasm of Gum 12
Malignant Gingival Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:8602
ICD10 33 C03 C03.9
ICD9CM 35 143 143.9
NCIt 50 C9317
UMLS 73 C0153364

Summaries for Gum Cancer

MalaCards based summary : Gum Cancer, also known as malignant tumor of gum, is related to lower gum cancer and upper gum cancer. An important gene associated with Gum Cancer is MMP8 (Matrix Metallopeptidase 8). Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Gum Cancer

Diseases related to Gum Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lower gum cancer 12.1
2 upper gum cancer 12.0
3 hypopharynx cancer 9.7 MMP8 SMUG1
4 oropharynx cancer 9.6 MMP8 SMUG1
5 lipid pneumonia 9.5 MMP8 SMUG1
6 pharynx cancer 9.2 MMP8 SMUG1

Graphical network of the top 20 diseases related to Gum Cancer:



Diseases related to Gum Cancer

Symptoms & Phenotypes for Gum Cancer

GenomeRNAi Phenotypes related to Gum Cancer according to GeneCards Suite gene sharing:

26 (show all 28)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.7 AGO2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.7 AGO2 MMP8
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.7 MMP8
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-150 9.7 AGO2
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.7 MMP8
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.7 MMP8
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-209 9.7 MMP8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.7 AGO2
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.7 AGO2
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.7 AGO2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.6 MMP8
12 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.6 AGO2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.6 AGO2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-125 9.6 AGO2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.6 AGO2
16 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.6 AGO2
17 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.6 AGO2
18 Increased shRNA abundance (Z-score > 2) GR00366-A-158 9.6 AGO2
19 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.6 MMP8
20 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.6 MMP8
21 Increased shRNA abundance (Z-score > 2) GR00366-A-208 9.6 MMP8
22 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.6 MMP8
23 Increased shRNA abundance (Z-score > 2) GR00366-A-45 9.6 AGO2
24 Increased shRNA abundance (Z-score > 2) GR00366-A-5 9.6 MMP8
25 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.6 MMP8
26 Increased shRNA abundance (Z-score > 2) GR00366-A-74 9.6 AGO2 MMP8
27 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.6 AGO2
28 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.6 MMP8

Drugs & Therapeutics for Gum Cancer

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Role of Imaging to Predict the Deep Surgical Margin in Gingivobuccal Complex Tumors Recruiting NCT03137953 Not Applicable

Search NIH Clinical Center for Gum Cancer

Genetic Tests for Gum Cancer

Anatomical Context for Gum Cancer

Publications for Gum Cancer

Variations for Gum Cancer

Expression for Gum Cancer

Search GEO for disease gene expression data for Gum Cancer.

Pathways for Gum Cancer

GO Terms for Gum Cancer

Molecular functions related to Gum Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 8.8 AGO2 MMP8 SMUG1

Sources for Gum Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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