Gum Cancer disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Gum Cancer

MalaCards integrated aliases for Gum Cancer:

Name: Gum Cancer ¹² ¹⁵

Malignant Tumor of Gum ¹² ⁷³

Malignant Neoplasm of Other Sites of Gum ¹²

Malignant Tumour of Gingiva ¹²

Malignant Neoplasm of Gum ¹²

Malignant Gingival Tumor ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Gastrointestinal diseases Oral diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Neoplasms

Malignant neoplasms of lip, oral cavity and pharynx

Malignant neoplasm of gum

Malignant neoplasm: Gum, unspecified

External Ids:

Disease Ontology ¹² DOID:8602

ICD10 ³³ C03 C03.9

ICD9CM ³⁵ 143 143.9

NCIt ⁵⁰ C9317

SNOMED-CT ⁶⁸ 187651005 363382005 93819009

UMLS ⁷³ C0153364

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Summaries for Gum Cancer

MalaCards based summary : Gum Cancer, also known as malignant tumor of gum, is related to lower gum cancer and upper gum cancer. An important gene associated with Gum Cancer is MMP8 (Matrix Metallopeptidase 8). Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

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Related Diseases for Gum Cancer

Diseases related to Gum Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

#	Related Disease	Score	Top Affiliating Genes
1	lower gum cancer	12.1
2	upper gum cancer	12.0
3	hypopharynx cancer	9.7	MMP8 SMUG1
4	oropharynx cancer	9.6	MMP8 SMUG1
5	lipid pneumonia	9.5	MMP8 SMUG1
6	pharynx cancer	9.2	MMP8 SMUG1

Graphical network of the top 20 diseases related to Gum Cancer:

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Symptoms & Phenotypes for Gum Cancer

GenomeRNAi Phenotypes related to Gum Cancer according to GeneCards Suite gene sharing:

²⁶ (show all 28)

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Decreased shRNA abundance (Z-score < -2)	GR00366-A-104	9.7	AGO2
2	Decreased shRNA abundance (Z-score < -2)	GR00366-A-139	9.7	AGO2 MMP8
3	Decreased shRNA abundance (Z-score < -2)	GR00366-A-145	9.7	MMP8
4	Decreased shRNA abundance (Z-score < -2)	GR00366-A-150	9.7	AGO2
5	Decreased shRNA abundance (Z-score < -2)	GR00366-A-184	9.7	MMP8
6	Decreased shRNA abundance (Z-score < -2)	GR00366-A-20	9.7	MMP8
7	Decreased shRNA abundance (Z-score < -2)	GR00366-A-209	9.7	MMP8
8	Decreased shRNA abundance (Z-score < -2)	GR00366-A-213	9.7	AGO2
9	Decreased shRNA abundance (Z-score < -2)	GR00366-A-216	9.7	AGO2
10	Decreased shRNA abundance (Z-score < -2)	GR00366-A-53	9.7	AGO2
11	Increased shRNA abundance (Z-score > 2)	GR00366-A-100	9.6	MMP8
12	Increased shRNA abundance (Z-score > 2)	GR00366-A-105	9.6	AGO2
13	Increased shRNA abundance (Z-score > 2)	GR00366-A-11	9.6	AGO2
14	Increased shRNA abundance (Z-score > 2)	GR00366-A-125	9.6	AGO2
15	Increased shRNA abundance (Z-score > 2)	GR00366-A-143	9.6	AGO2
16	Increased shRNA abundance (Z-score > 2)	GR00366-A-149	9.6	AGO2
17	Increased shRNA abundance (Z-score > 2)	GR00366-A-156	9.6	AGO2
18	Increased shRNA abundance (Z-score > 2)	GR00366-A-158	9.6	AGO2
19	Increased shRNA abundance (Z-score > 2)	GR00366-A-176	9.6	MMP8
20	Increased shRNA abundance (Z-score > 2)	GR00366-A-199	9.6	MMP8
21	Increased shRNA abundance (Z-score > 2)	GR00366-A-208	9.6	MMP8
22	Increased shRNA abundance (Z-score > 2)	GR00366-A-41	9.6	MMP8
23	Increased shRNA abundance (Z-score > 2)	GR00366-A-45	9.6	AGO2
24	Increased shRNA abundance (Z-score > 2)	GR00366-A-5	9.6	MMP8
25	Increased shRNA abundance (Z-score > 2)	GR00366-A-52	9.6	MMP8
26	Increased shRNA abundance (Z-score > 2)	GR00366-A-74	9.6	AGO2 MMP8
27	Increased shRNA abundance (Z-score > 2)	GR00366-A-85	9.6	AGO2
28	Increased shRNA abundance (Z-score > 2)	GR00366-A-99	9.6	MMP8

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Drugs & Therapeutics for Gum Cancer

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Role of Imaging to Predict the Deep Surgical Margin in Gingivobuccal Complex Tumors	Recruiting	NCT03137953	Not Applicable

Search NIH Clinical Center for Gum Cancer

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Genetic Tests for Gum Cancer

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Anatomical Context for Gum Cancer

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Publications for Gum Cancer

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Genes for Gum Cancer

Genes related to Gum Cancer (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MMP8	Matrix Metallopeptidase 8	Protein Coding	15.76	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
2	AGO2	Argonaute 2, RISC Catalytic Component	Protein Coding	15.42	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)
3	SMUG1	Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1	Protein Coding	13.74	DISEASES inferred ¹⁵ GeneCards inferred via : DISEASES inferred (show sections)

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Variations for Gum Cancer

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Expression for Gum Cancer

Search GEO for disease gene expression data for Gum Cancer.

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Pathways for Gum Cancer

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GO Terms for Gum Cancer

Molecular functions related to Gum Cancer according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	hydrolase activity	GO:0016787	8.8	AGO2 MMP8 SMUG1

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Sources for Gum Cancer

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia