MCID: HMP009
MIFTS: 49

Haemophilus Influenzae

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Haemophilus Influenzae

Summaries for Haemophilus Influenzae

MalaCards based summary : Haemophilus Influenzae, also known as h. influenzae, is related to septic arthritis and pulmonary disease, chronic obstructive. An important gene associated with Haemophilus Influenzae is OMP (Olfactory Marker Protein), and among its related pathways/superpathways are Innate Immune System and Influenza A. The drugs Amoxicillin and Iron have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and colon, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 76 Haemophilus influenzae (formerly called Pfeiffer\'s bacillus or Bacillus influenzae) is a Gram-negative,... more...

Related Diseases for Haemophilus Influenzae

Diseases related to Haemophilus Influenzae via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 278)
# Related Disease Score Top Affiliating Genes
1 septic arthritis 30.9 CXCL8 TLR2
2 pulmonary disease, chronic obstructive 30.3 CXCL8 TLR2 TNF
3 endocarditis 30.2 CXCL8 TLR2 TNF
4 pharyngitis 29.8 CXCL8 IL1B
5 tonsillitis 29.7 CXCL8 IL1B TNF
6 pneumonia 29.7 CXCL8 IL1B TLR2 TNF
7 fasciitis 29.7 CXCL8 TNF
8 otitis media 29.6 CXCL8 IL1B TLR2 TNF
9 endometritis 29.3 IL1B TNF
10 meningitis 29.2 CXCL8 IL1B OMP TLR2 TNF
11 aseptic meningitis 29.1 CXCL8 IL1B TNF
12 prostatitis 29.1 CXCL8 IL1B TNF
13 pyelonephritis 29.1 CXCL8 IL1B TNF
14 chorioamnionitis 29.1 CXCL8 IL1B TNF
15 duodenal ulcer 29.1 CXCL8 IL1B TNF
16 osteomyelitis 29.1 CXCL8 IL1B TNF
17 bacterial meningitis 29.0 CXCL8 IL1B TLR2 TNF
18 lung disease 28.9 CXCL8 IL1B TLR2 TNF
19 peritonitis 28.8 CXCL8 IL1B TLR2 TNF
20 arthritis 28.7 CXCL8 IL1B TNF
21 haemophilus meningitis 11.7
22 epiglottitis 11.5
23 influenza 11.2
24 complement component 3 deficiency, autosomal recessive 11.1
25 specific antibody deficiency 11.1
26 bronchitis 10.8
27 tetanus 10.7
28 mycobacterium chelonae 10.7 CXCL8 TLR2
29 mycobacterium kansasii 10.7 CXCL8 TLR2
30 neurosyphilis 10.7 CXCL8 TLR2
31 pertussis 10.6
32 diphtheria 10.6
33 tungiasis 10.6 CXCL8 TNF
34 streptococcal toxic-shock syndrome 10.6 CXCL8 TNF
35 trichuriasis 10.6 CXCL8 TNF
36 clonorchiasis 10.5 CXCL8 TNF
37 sebaceous gland disease 10.5 CXCL8 TLR2
38 neisseria meningitidis infection 10.5 OMP TLR2
39 meconium aspiration syndrome 10.5 CXCL8 TNF
40 pouchitis 10.5 CXCL8 LTF
41 melancholia 10.5 TF TNF
42 hepatitis 10.5
43 giant papillary conjunctivitis 10.5 CXCL8 LTF
44 hepatitis b 10.5
45 louse-borne relapsing fever 10.5 CXCL8 TNF
46 trench fever 10.5 TLR2 TNF
47 superficial siderosis of the central nervous system 10.5 LTF TF
48 superficial siderosis 10.5 LTF TF
49 transverse myelitis 10.5 CXCL8 TNF
50 aging 10.5

Graphical network of the top 20 diseases related to Haemophilus Influenzae:



Diseases related to Haemophilus Influenzae

Symptoms & Phenotypes for Haemophilus Influenzae

MGI Mouse Phenotypes related to Haemophilus Influenzae:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.56 TF TLR2 TNF VTN CFH CLEC7A
2 homeostasis/metabolism MP:0005376 9.28 TLR2 TNF VTN CFH CLEC7A IL1B

Drugs & Therapeutics for Haemophilus Influenzae

Drugs for Haemophilus Influenzae (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 187)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 26787-78-0 33613
2
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
3
Azithromycin Approved Phase 4,Phase 3 83905-01-5 55185 447043
4
Moxifloxacin Approved, Investigational Phase 4 354812-41-2, 151096-09-2 152946
5 Estradiol valerate Approved, Investigational, Vet_approved Phase 4 979-32-8
6
Acetaminophen Approved Phase 4,Phase 3 103-90-2 1983
7
Ibuprofen Approved Phase 4,Phase 2 15687-27-1 3672
8
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
9
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
10
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
11
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 60-00-4, 62-33-9 6049
12
Polyestradiol phosphate Approved Phase 4 28014-46-2
13
Pentetic acid Approved Phase 4,Phase 3,Phase 2 67-43-6
14 Olodaterol Approved Phase 4 868049-49-4
15
Fluticasone Approved, Experimental, Investigational Phase 4 90566-53-3 62924
16 Strawberry Approved, Nutraceutical Phase 4,Phase 3
17
BCG vaccine Investigational Phase 4,Not Applicable
18 Clavulanic Acid Phase 4,Phase 3,Phase 2,Not Applicable
19 Fluoroquinolones Phase 4,Phase 3,Not Applicable
20 Amoxicillin-Potassium Clavulanate Combination Phase 4,Phase 3,Phase 2,Not Applicable
21 Heptavalent Pneumococcal Conjugate Vaccine Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
22 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
23 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Not Applicable
24 Vaccines Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 Anti-Bacterial Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
26 Antibodies Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 Immunoglobulins Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
28 Anti-Infective Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
29 beta-Lactamase Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
30 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
31 Respiratory System Agents Phase 4,Not Applicable
32 Adjuvants, Immunologic Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
33 MF59 oil emulsion Phase 4
34 Chelating Agents Phase 4,Phase 3,Phase 2
35 Aluminum phosphate Phase 4,Phase 2,Phase 1
36 Contraceptive Agents Phase 4
37 Contraceptives, Oral Phase 4
38 Contraceptives, Oral, Combined Phase 4
39 Neurotransmitter Agents Phase 4,Phase 1,Not Applicable
40 Cyclooxygenase Inhibitors Phase 4,Phase 2
41 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2
42 Tetanus Antitoxin Phase 4,Phase 3
43 Norgestimate, ethinyl estradiol drug combination Phase 4
44 Ophthalmic Solutions Phase 4
45 Diphtheria Antitoxin Phase 4,Phase 3
46 Anti-Asthmatic Agents Phase 4,Not Applicable
47 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
48 Estradiol 17 beta-cypionate Phase 4
49 Estradiol 3-benzoate Phase 4
50 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 333)
# Name Status NCT ID Phase Drugs
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination Vaccine Unknown status NCT00877357 Phase 4
3 Safety of Haemophilus Influenza Type b Vaccine When Administered to Korean Children Completed NCT01404962 Phase 4
4 The Safety and Immunogenicity of Haemophilus Influenzae Type b Vaccine in Different Injection Site Completed NCT01761136 Phase 4
5 Assess Safety & Reactogenicity of GSK Biologicals' Hib Vaccine Co-administered With or Without Chinese DTPw Vaccine Completed NCT00158795 Phase 4
6 Study to Eliminate Hib Carriage in Rural Alaska Native Villages Completed NCT00153556 Phase 4
7 The Immediate and Longterm Immune Responses of UK Infants and Young Children to a Booster Dose of Hib Vaccine Completed NCT00197782 Phase 4
8 Study of Long-term Antibody Persistence After a Booster Dose of Menitorix Vaccine Completed NCT00454987 Phase 4
9 Immunogenicity and Safety Study of Infanrix Hexa in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Completed NCT02422264 Phase 4 Prevnar13
10 Hepatitis B Vaccination in Infants Completed NCT01896596 Phase 4
11 Immunogenicity of the Booster Dose of Two MenC Vaccines Completed NCT00392808 Phase 4
12 Immunogenicity and Safety of PCV13 and Fluad in Adults Aged ≥60 Years Completed NCT02215863 Phase 4
13 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
14 Topical Treatment of Bacterial Conjunctivitis and Its Effect on Microbial Flora Completed NCT00312338 Phase 4 VIGAMOX
15 Phase IV Interchangeability Study of a Liquid Pentavalent Combination Vaccine Completed NCT00674908 Phase 4
16 Safety and Immunogenicity Study of a Liquid Pentavalent Combination Vaccine Completed NCT00617812 Phase 4
17 Concomitant Use of Hepatitis A Vaccine, Inactivated With Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate) and Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed Given to Healthy Children 15 Months of Age (V251-068) Completed NCT00289913 Phase 4
18 Assess the Safety & Reactogenicity of DTPa-IPV/Hib Vaccine Administered at 3, 4, 5 & 18 Mths of Age, in Healthy Infants Completed NCT00325156 Phase 4
19 Assessment of the Immunogenicity and Safety of PENTAXIM™ in Philippines Completed NCT00254917 Phase 4
20 Study to Evaluate Antibody Persistence in Children Previously Vaccinated With Infanrix Hexa™ or Infanrix-IPV/Hib™ Completed NCT01358825 Phase 4
21 Comparison of Immunogenicity and Reactogenicity of INFANRIX™ HEXA and HEXAVAC™ Vaccines as a Primary Vaccination Course Completed NCT01457547 Phase 4
22 Immunogenicity and Safety of GSK Biologicals' Infanrix Hexa in Infants Completed NCT00753649 Phase 4
23 Study of Menactra® in Healthy Subjects at 9 Months and Concomitantly With Pentacel® at 15 to 18 Months of Age Completed NCT01659996 Phase 4
24 Effectiveness of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders Completed NCT03533335 Phase 4
25 Study Assessing the Effect of Medications to Prevent Fever on Prevenar 13® Completed NCT01392378 Phase 4 Paracetamol;Ibuprofen;Paracetamol;Ibuprofen
26 Study of DAPTACEL® Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™ Completed NCT00802867 Phase 4
27 Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand Completed NCT00255021 Phase 4
28 Safety of PENTAXIM® Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China Completed NCT01491087 Phase 4
29 Study to Assess if Quinvaxem Can be Interchanged With Other Pentavalent Vaccines During Standard Childhood Vaccination Completed NCT01357720 Phase 4
30 Efficacy and Safety of Vivaglobin® in Previously Untreated Patients With Primary Immunodeficiency Completed NCT00520494 Phase 4 Vivaglobin
31 Acute Otitis Media (AOM) Therapy Trial in Young Children Completed NCT00377260 Phase 4 amoxicillin-clavulanate;Placebo
32 Tripartite International Research for the Elimination of Trachoma Completed NCT01202331 Phase 4 mass treatment with oral azithromycin
33 Bacille Calmette Guérin Immunisation at Birth and Childhood Morbidity in Danish Children. Completed NCT01694108 Phase 4
34 Vaccinating Children After Chemotherapy Recruiting NCT02447718 Phase 4
35 INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol Recruiting NCT03152149 Phase 4 Tiotropium & olodaterol;fluticasone furoate & vilanterol
36 Babies Born Early Antibody Response to Men B Vaccination: BEAR Men B Active, not recruiting NCT03125616 Phase 4
37 Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Active, not recruiting NCT02853929 Phase 4
38 Pneumococcal Vaccines Early and in Combination Active, not recruiting NCT01174849 Phase 4 Synflorix;Prevenar13;COMBO
39 Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines Not yet recruiting NCT03530124 Phase 4
40 Study Comparing DTP-HB-Hib by Disposable-Syringe Jet Injector To Vaccination By Needle And Syringe In Infants Terminated NCT02409095 Phase 4
41 Safety and Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccine,Freeze-dried Unknown status NCT02560272 Phase 3
42 Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines in Papua New Guinean Children Unknown status NCT01619462 Phase 3
43 Randomized Study on Efficacy of Gemifloxacin-based Regimen for Helicobacter Pylori Infection Unknown status NCT02368470 Phase 3 Gemifloxacin-based triple therapy;Standard triple therapy
44 Study in Toddlers (12-18 Months) Comparing a Booster Dose of Vaxem Hib and Hiberix Vaccines for the Prevention of Haemophilus Influenzae Type b Infections in China Completed NCT01025544 Phase 3
45 Safety and Immunogenicity of a Monovalent Conjugated Vaccine Against Haemophilus Influenzae Type b Completed NCT00808392 Phase 3
46 Study in Infants (6-12 Months) Comparing Two Doses of a Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Vaccine Versus a Tetanus Toxoid-Conjugated Vaccine Available for the Prevention of Haemophilus Influenzae Type b Infections in China Completed NCT01044316 Phase 3
47 A Phase III Clinical Trial of a Haemophilus Influenzae Type b (Hib) Conjugate Vaccine Completed NCT02692859 Phase 3
48 Immunogenicity and Safety of a Booster Dose of Monovalent Glycoprotein-Conjugated (Diptheria Toxin -CRM197) Hib Vaccine in 365-569 Days Old Healthy Infants Completed NCT01226953 Phase 3
49 Persistency Study After Hib-CRM (Cross-Reacting Material)197 or Hib-TT (Tetanus Toxoid) Vaccines in Chinese Children Completed NCT02139228 Phase 3
50 Study of Modified Process Hib/Hep B Vaccine in Infants (V121-019)(COMPLETED) Completed NCT00441012 Phase 3

Search NIH Clinical Center for Haemophilus Influenzae

Genetic Tests for Haemophilus Influenzae

Anatomical Context for Haemophilus Influenzae

MalaCards organs/tissues related to Haemophilus Influenzae:

41
Lung, Testes, Colon, Neutrophil, B Cells, Tonsil, Monocytes

Publications for Haemophilus Influenzae

Articles related to Haemophilus Influenzae:

(show top 50) (show all 686)
# Title Authors Year
1
Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway. ( 29421524 )
2018
2
Mutant selection window of four quinolone antibiotics against clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis. ( 29290527 )
2018
3
Nontypeable Haemophilus Influenzae Sepsis in a Term Neonate. ( 29955021 )
2018
4
Single nucleotide polymorphisms in genes encoding penicillin-binding proteins in I^-lactamase-negative ampicillin-resistant Haemophilus influenzae in Japan. ( 29352811 )
2018
5
Carbapenem-non-Susceptible <i>Haemophilus influenzae</i> with Penicillin-Binding Protein 3 containing Amino Acid Insertion. ( 29784853 )
2018
6
Long-term exposure to low-dose <i>Haemophilus influenzae</i> during allergic airway disease drives a steroid-resistant neutrophilic inflammation and promotes airway remodeling. ( 29861841 )
2018
7
Immunologic non-inferiority and safety of the investigational pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) 4-dose vial presentation compared to the licensed PHiD-CV 1-dose vial presentation in infants: A phase III randomized study. ( 29277353 )
2018
8
Pneumococcal phenotype and interaction with nontypeable<i>Haemophilus influenzae</i>as determinants of otitis media progression. ( 29378791 )
2018
9
A novel PBP3 substitution in Haemophilus influenzae confers reduced aminopenicillin susceptibility. ( 29855260 )
2018
10
Coverage of Haemophilus influenzae Type b Conjugate Vaccine for Children in Mainland China: Systematic Review and Meta-Analysis. ( 29957731 )
2018
11
Antibacterial activity of Artemisia asiatica essential oil against some common respiratory infection causing bacterial strains and its mechanism of action in Haemophilus influenzae. ( 29241769 )
2018
12
Molecular diagnosis and characterization of a culture-negative mycotic aneurysm due to ST54 Haemophilus influenzae type b with PBP 3 alterations. ( 29373266 )
2018
13
Phenotypic detection of clinical isolates of Haemophilus influenzae with altered penicillin-binding protein 3. ( 29756174 )
2018
14
The HMW2 adhesin of non-typeable Haemophilus influenzae is a human-adapted lectin that mediates high-affinity binding to 2-6 linked N-acetylneuraminic acid glycans. ( 29944882 )
2018
15
Pneumococcal and Haemophilus influenzae type b disease: moving numbers in the right direction. ( 29903364 )
2018
16
Nontypeable Haemophilus influenzae (NTHi). ( 29793827 )
2018
17
Recommendations for application of Haemophilus influenzae PCR diagnostics to respiratory specimens for children living in northern Australia: a retrospective re-analysis. ( 29784027 )
2018
18
Update on non-typeable Haemophilus influenzae-mediated disease and vaccine development. ( 29863956 )
2018
19
MLVA typing of <i>Haemophilus influenzae</i> isolated from two Iranian university hospitals. ( 29922416 )
2018
20
Immunization of preterms with hexavalent combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b conjugate vaccine: The position of the Italian Pediatric Society. ( 29880242 )
2018
21
Benzylpenicillin versus wide-spectrum beta-lactam antibiotics as empirical treatment of Haemophilus influenzae-associated lower respiratory tract infections in adults; a retrospective propensity score-matched study. ( 29961165 )
2018
22
The adhesins of non-typeable Haemophilus influenzae. ( 29415569 )
2018
23
Changing Epidemiology of Haemophilus influenzae in Children. ( 29233576 )
2018
24
GyrA and/or ParC alterations of Haemophilus influenzae strains isolated from the urethra of men with acute urethritis. ( 29138021 )
2018
25
Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000-15. ( 29903376 )
2018
26
Immunization of preterm infants with GSK's hexavalent combined diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b conjugate vaccine: A review of safety and immunogenicity. ( 29336924 )
2018
27
Haemophilus influenzae-protein D specific antibody correlate with protection against acute otitis media in young children. ( 29395516 )
2018
28
Antimicrobial activity of a novel bioengineered honey against non-typeable<i>Haemophilus influenzae</i>biofilms: an in vitro study. ( 29449345 )
2018
29
Azithromycin Pharmacodynamics against Persistent Haemophilus influenzae in Chronic Obstructive Pulmonary Disease. ( 29180527 )
2018
30
Commentary: The Conquest of Haemophilus influenzae Type B-The Importance of Protecting High-Risk Children. ( 29889812 )
2018
31
Antibodies prevalence against Haemophilus influenzae type b in Jeddah population, Saudi Arabia. I. Total antibodies. ( 29945350 )
2018
32
Changes in IgA protease expression are conferred by changes in genomes during persistent infection by nontypeable <i>Haemophilus influenzae</i> in chronic obstructive pulmonary disease. ( 29760213 )
2018
33
Epidemiology of invasive pneumococcal and haemophilus influenzae diseases in northwestern ontario, canada (2010-2015). ( 28951105 )
2017
34
Experimental design and metabolic flux analysis tools to optimize industrially relevant Haemophilus influenzae type b growth medium. ( 28840658 )
2017
35
Decreased AOM with Treatment Failure Following Introduction of the Ten-Valent Pneumococcal Haemophilus influenzae Protein D Conjugate Vaccine. ( 29278616 )
2017
36
Haemophilus influenzae type b (Hib) seroprevalence and current epidemiology in England and Wales. ( 29289561 )
2017
37
Response to Effectiveness of the 10-Valent Pneumococcal Nontypeable Haemophilus influenzae Protein D-Conjugated Vaccine (PHiD-CV) Against Carriage and Acute Otitis Media-A Double-Blind Randomized Clinical Trial in Finland. ( 28064237 )
2017
38
Immunogenicity, safety and reactogenicity of the pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) in 2-17-year-old children with asplenia or splenic dysfunction: A phase 3 study. ( 28866290 )
2017
39
Blood-Brain Barrier in a Haemophilus influenzae Type a In Vitro Infection: Role of Adenosine Receptors A2A and A2B. ( 28921456 )
2017
40
Vaccine Candidates against Nontypeable Haemophilus influenzae: a Review ( 28088130 )
2017
41
Nontypeable Haemophilus influenzae (NTHi) directly interfere with the regulation of E-cadherin in lung epithelial cells. ( 28802586 )
2017
42
Budget impact analysis of vaccination against Haemophilus influenzae type b as a part of a Pentavalent vaccine in the childhood immunization schedule of Iran. ( 28088246 )
2017
43
Haemophilus influenzae serotype f endocarditis and septic arthritis. ( 28725560 )
2017
44
Antimicrobial activity of antisense peptide-peptide nucleic acid conjugates against non-typeable Haemophilus influenzae in planktonic and biofilm forms. ( 27986898 )
2017
45
The DNABII family of proteins is comprised of the only nucleoid associated proteins required for nontypeable Haemophilus influenzae biofilm structure. ( 29230970 )
2017
46
Safety profile of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV). ( 26954689 )
2017
47
Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution. ( 28887305 )
2017
48
Pneumonia prevention: Cost-effectiveness analyses of two vaccines among refugee children aged under two years, Haemophilus influenzae type b-containing and pneumococcal conjugate vaccines, during a humanitarian emergency, Yida camp, South Sudan. ( 27989625 )
2017
49
Primary ciliary dyskinesia ciliated airwayA cells show increased susceptibility to Haemophilus influenzae biofilm formation. ( 28890436 )
2017
50
Alloiococcus otitidis Forms Multispecies Biofilm with Haemophilus influenzae: Effects on Antibiotic Susceptibility and Growth in Adverse Conditions. ( 28824879 )
2017

Variations for Haemophilus Influenzae

Expression for Haemophilus Influenzae

Search GEO for disease gene expression data for Haemophilus Influenzae.

Pathways for Haemophilus Influenzae

Pathways related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

(show all 39)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.79 CFH CLEC7A CXCL8 IL1B LTF TLR2
2
Show member pathways
12.61 CXCL8 IL1B TLR2 TNF
3
Show member pathways
12.34 IL1B TLR2 TNF
4 12.14 TLR2 TNF VTN
5
Show member pathways
12.13 CXCL8 IL1B TLR2 TNF
6
Show member pathways
12.11 CXCL8 TLR2 TNF
7
Show member pathways
12.1 IL1B TLR2 TNF
8
Show member pathways
12.1 IL1B TLR2 TNF
9
Show member pathways
12.1 CXCL8 IL1B TNF
10
Show member pathways
12.05 CLEC7A IL1B TNF
11 11.99 CLEC7A IL1B TLR2 TNF
12
Show member pathways
11.95 CXCL8 IL1B TLR2 TNF
13
Show member pathways
11.89 CXCL8 IL1B TLR2 TNF
14 11.85 CXCL8 IL1B TNF
15 11.83 CXCL8 IL1B TF TNF
16 11.82 CXCL8 IL1B TNF
17 11.78 CXCL8 IL1B VTN
18 11.74 CXCL8 IL1B TNF
19 11.71 CXCL8 IL1B TNF
20 11.65 CLEC7A TLR2 VTN
21 11.59 CXCL8 IL1B TNF
22 11.54 CXCL8 IL1B TLR2 TNF
23 11.5 CXCL8 IL1B TNF
24
Show member pathways
11.49 CXCL8 IL1B TNF
25 11.41 CXCL8 IL1B TLR2 TNF
26 11.34 CXCL8 IL1B TNF
27 11.31 IL1B TLR2 TNF
28 11.22 IL1B TNF
29 11.22 IL1B TNF
30 11.18 IL1B TNF
31 11.16 IL1B TNF
32 11.14 IL1B TNF
33 11.04 IL1B TLR2
34 11.02 CXCL8 TNF
35 11 CXCL8 IL1B TLR2 TNF
36 10.97 IL1B TNF
37 10.89 CXCL8 TNF
38 10.81 IL1B TNF
39 10.61 CXCL8 IL1B TLR2 TNF

GO Terms for Haemophilus Influenzae

Cellular components related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell surface GO:0009986 9.62 LTF TF TLR2 TNF
2 extracellular region GO:0005576 9.5 CFH CXCL8 IL1B LTF TF TNF
3 blood microparticle GO:0072562 9.43 CFH TF VTN
4 extracellular space GO:0005615 9.17 CFH CXCL8 IL1B LTF TF TNF
5 signal recognition particle receptor complex GO:0005785 9.16 LTF TF

Biological processes related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 response to lipopolysaccharide GO:0032496 9.78 CXCL8 IL1B TLR2
2 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.77 IL1B LTF TNF
3 immune response GO:0006955 9.77 CXCL8 IL1B TLR2 TNF VTN
4 inflammatory response GO:0006954 9.65 CLEC7A CXCL8 IL1B TLR2 TNF
5 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 9.62 IL1B TNF
6 positive regulation of phagocytosis GO:0050766 9.62 IL1B TNF
7 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 IL1B TNF
8 positive regulation of interleukin-6 production GO:0032755 9.61 IL1B TLR2 TNF
9 positive regulation of receptor-mediated endocytosis GO:0048260 9.59 TF VTN
10 positive regulation of chemokine production GO:0032722 9.58 TLR2 TNF
11 positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 9.58 IL1B VTN
12 positive regulation of NIK/NF-kappaB signaling GO:1901224 9.58 IL1B TLR2 TNF
13 embryonic digestive tract development GO:0048566 9.57 CXCL8 TNF
14 negative regulation of lipid catabolic process GO:0050995 9.56 IL1B TNF
15 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.55 IL1B TNF
16 response to molecule of bacterial origin GO:0002237 9.54 CXCL8 TLR2
17 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.52 IL1B TNF
18 positive regulation of chemokine biosynthetic process GO:0045080 9.51 IL1B TNF
19 regulation of establishment of endothelial barrier GO:1903140 9.49 IL1B TNF
20 positive regulation of fever generation GO:0031622 9.48 IL1B TNF
21 sequestering of triglyceride GO:0030730 9.46 IL1B TNF
22 lipopolysaccharide-mediated signaling pathway GO:0031663 9.33 IL1B TLR2 TNF
23 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.32 IL1B TNF
24 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.26 IL1B LTF TLR2 TNF
25 positive regulation of interleukin-8 production GO:0032757 8.8 IL1B TLR2 TNF

Molecular functions related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.43 CXCL8 IL1B TNF
2 heparin binding GO:0008201 9.33 CFH LTF VTN
3 lipopolysaccharide binding GO:0001530 9.32 LTF TLR2
4 signal recognition particle binding GO:0005047 8.96 LTF TF
5 signaling pattern recognition receptor activity GO:0008329 8.62 CLEC7A TLR2

Sources for Haemophilus Influenzae

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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