MCID: HMP009
MIFTS: 42

Haemophilus Influenzae

Categories: Infectious diseases, Rare diseases

Aliases & Classifications for Haemophilus Influenzae

Summaries for Haemophilus Influenzae

MalaCards based summary : Haemophilus Influenzae, also known as h. influenzae, is related to epiglottitis and bacterial meningitis. An important gene associated with Haemophilus Influenzae is LACTB (Lactamase Beta), and among its related pathways/superpathways are IL-17 Family Signaling Pathways and Proteoglycans in cancer. The drugs Methylprednisolone hemisuccinate and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include testes, lung and colon, and related phenotype is homeostasis/metabolism.

Wikipedia : 74 Haemophilus influenzae (formerly called Pfeiffer's bacillus or Bacillus influenzae) is a Gram-negative,... more...

Related Diseases for Haemophilus Influenzae

Diseases related to Haemophilus Influenzae via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 570)
# Related Disease Score Top Affiliating Genes
1 epiglottitis 33.4 OMP LACTB
2 bacterial meningitis 32.4 TNF TLR2 LACTB CXCL8
3 meningitis 31.5 TNF TLR2 LACTB CXCL8
4 otitis media 31.4 TNF TLR2 LACTB CXCL8
5 pneumonia 31.0 VTN TNF TLR2 LACTB CXCL8
6 bronchitis 30.9 TNF TLR2 LTF LACTB CXCL8
7 pericarditis 30.9 VTN TNF CXCL8
8 osteomyelitis 30.8 TNF TLR2 CXCL8
9 neisseria meningitidis infection 30.8 TLR2 OMP LACTB
10 bronchopneumonia 30.7 TNF CXCL8
11 bronchiectasis 30.7 TNF TLR2 CXCL8
12 lung abscess 30.7 TNF LACTB
13 cholera 30.7 TNF TF CXCL8
14 salpingitis 30.6 TNF TLR2
15 peritonitis 30.5 TNF TLR2 CXCL8
16 endophthalmitis 30.5 TNF TLR2 CXCL8
17 toxic shock syndrome 30.5 TNF TLR2 CXCL8
18 acute cystitis 30.5 TNF TLR2 CXCL8
19 endocarditis 30.5 TNF TLR2 LACTB CXCL8
20 pharyngitis 30.4 TNF LACTB CXCL8
21 urethritis 30.4 TNF TLR2 CXCL8
22 tonsillitis 30.3 TNF TLR2 LACTB CXCL8
23 pulmonary disease, chronic obstructive 30.3 TNF TLR2 CXCL8
24 bacterial infectious disease 30.2 TNF TLR2 LTF CXCL8
25 meningococcal meningitis 30.2 TLR2 CFH
26 bacterial pneumonia 30.2 TNF TLR2 LACTB CXCL8
27 streptococcus pneumonia 30.2 TNF TLR2 CXCL8
28 vaginitis 30.2 TNF TLR2 CXCL8
29 keratitis, hereditary 30.2 TNF TLR2 CXCL8
30 gastroenteritis 30.2 TNF LACTB CXCL8
31 middle ear disease 30.1 TNF TLR2 CXCL8
32 bacterial sepsis 30.1 TNF TLR2 CXCL8
33 pustulosis of palm and sole 30.1 TNF CXCL8
34 cervicitis 30.1 TLR2 CXCL8
35 chlamydia 30.0 TNF TLR2 CXCL8
36 dermatitis 30.0 TNF TLR2 CXCL8
37 bronchiolitis 30.0 TNF TLR2 CXCL8
38 aseptic meningitis 29.9 TNF LTF CXCL8
39 preterm premature rupture of the membranes 29.9 TNF TLR2 CXCL8
40 common cold 29.9 TNF TLR2 CXCL8
41 endometritis 29.8 TNF TLR2 LACTB CXCL8
42 chlamydia pneumonia 29.7 TNF TLR2 CXCL8
43 periodontitis 29.7 TNF TLR2 CXCL8
44 aphthous stomatitis 29.7 TNF TLR2 CXCL8
45 proteasome-associated autoinflammatory syndrome 1 29.6 TNF TLR2 CXCL8
46 alcoholic hepatitis 29.6 TNF TLR2 CXCL8
47 chronic mucocutaneous candidiasis 29.6 TNF TLR2 CLEC7A
48 food allergy 29.6 TNF TLR2 CXCL8
49 gout 29.6 TNF TLR2 CXCL8
50 tuberculous meningitis 29.5 TNF TLR2 CXCL8

Graphical network of the top 20 diseases related to Haemophilus Influenzae:



Diseases related to Haemophilus Influenzae

Symptoms & Phenotypes for Haemophilus Influenzae

MGI Mouse Phenotypes related to Haemophilus Influenzae:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.28 CFH CLEC7A LACTB LTF OMP TF

Drugs & Therapeutics for Haemophilus Influenzae

Drugs for Haemophilus Influenzae (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 182)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone hemisuccinate Approved Phase 4 2921-57-5
2
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
3
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
4
Prednisolone phosphate Approved, Vet_approved Phase 4 302-25-0
5 Prednisolone acetate Approved, Vet_approved Phase 4 52-21-1
6
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
7
Clavulanate Approved, Vet_approved Phase 4 58001-44-8 5280980
8
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
9 Strawberry Approved Phase 4
10
Olodaterol Approved Phase 4 868049-49-4
11
Temocillin Approved, Investigational Phase 4 66148-78-5
12
Budesonide Approved Phase 4 51333-22-3 63006 5281004
13
Prednisolone hemisuccinate Experimental Phase 4 2920-86-7
14 Chlorine dioxide Investigational Phase 4 10049-04-4
15 Anti-Inflammatory Agents Phase 4
16 Methylprednisolone Acetate Phase 4
17 Antineoplastic Agents, Hormonal Phase 4
18 Antitoxins Phase 4
19 Chlorhexidine gluconate Phase 4
20 Disinfectants Phase 4
21 Anti-Infective Agents, Local Phase 4
22 Amoxicillin-Potassium Clavulanate Combination Phase 4
23 beta-Lactamase Inhibitors Phase 4
24 Micronutrients Phase 4
25 Trace Elements Phase 4
26 Nutrients Phase 4
27 Antitubercular Agents Phase 4
28 Anti-Infective Agents Phase 4
29 Tiotropium Bromide Phase 4 136310-93-5
30 Cholinergic Antagonists Phase 4
31 Cholinergic Agents Phase 4
32 Parasympatholytics Phase 4
33 penicillins Phase 4
34 Aluminum phosphate Phase 4
35 Neurotransmitter Agents Phase 4
36 Sympathomimetics Phase 4
37 Adrenergic Agonists Phase 4
38 Formoterol Fumarate Phase 4
39 Adrenergic beta-Agonists Phase 4
40
Salmeterol xinafoate Phase 4 94749-08-3 56801
41 Hormone Antagonists Phase 4
42 Anticonvulsants Phase 4
43 Adrenergic Agents Phase 4
44 Fluticasone-Salmeterol Drug Combination Phase 4
45 glucocorticoids Phase 4
46 Bromides Phase 4
47 Budesonide, Formoterol Fumarate Drug Combination Phase 4
48 Hormones Phase 4
49
Gemifloxacin Approved, Investigational Phase 3 175463-14-6 5464436 9571107
50
Rabeprazole Approved, Investigational Phase 3 117976-89-3 5029

Interventional clinical trials:

(show top 50) (show all 258)
# Name Status NCT ID Phase Drugs
1 Open Label Multicentric Randomized Phase IV Post Marketing Safety, Immunogenicity and Lot-to-Lot Consistency Analysis of Shan 5 [DTPwHB-Hib (Liquid) Pentavalent Combination Vaccine] in Indian Infants Unknown status NCT00877357 Phase 4
2 Clinical Relevance of Middle Meatal Bacteriology During Acute Respiratory Infection in Children - Randomised, Double-Blinded Clinical Study Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
3 Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children Unknown status NCT00494624 Phase 4 prednisolone
4 Phase 4 Study of Haemophilus Influenzae Type b Vaccine in Different Injection Site Completed NCT01761136 Phase 4
5 Immunogenicity and Safety of Sanofi Pasteur Pentaxim Combined Vaccine in Infants in Thailand Completed NCT00255021 Phase 4
6 The Immediate and Longterm Immune Responses of UK Infants and Young Children to a Booster Dose of Hib Vaccine Completed NCT00197782 Phase 4
7 An Open Label Multicentric Study to Evaluate the Immunogenicity and Safety of Indigenously Developed DTPwHB-Hib (Liquid) Pentavalent Combination Vaccine (Shan 5) in Indian Infants. Completed NCT00617812 Phase 4
8 Assess the Safety & Reactogenicity of GSK Biologicals Hib Vaccine Co-administered With Chinese Local DTPw Vaccine When Compared to Chinese Local DTPw Vaccine Administered Alone, in Healthy Infants at 3,4 & 5 Mths of Age Completed NCT00158795 Phase 4
9 A Post Marketing Surveillance Study to Monitor the Reactogenicity and Safety of Vaxem™Hib When Administered According to the Prescribing Information in Korea Completed NCT01404962 Phase 4
10 A Single Blind, Multicentric, Comparative, Vaccine Interchangeability Trial of Shan 5 (Liquid) and Easy Five (Liquid) [Diphtheria-Tetanus- Pertussis, Hepatitis B and Hib Pentavalent Combination Vaccines] in Indian Infants. Completed NCT00674908 Phase 4
11 A Demonstration Project for the Elimination of Haemophilus Influenzae Type B in Three Rural Alaska Native Villages Completed NCT00153556 Phase 4
12 A Randomized Clinical Trial on the Effect of a Chlorine Dioxide Spray on Dental Plaque and Respiratory Pathogens in Institutionalized Elders Completed NCT03533335 Phase 4
13 Safety of the DTacP-IPV//PRP~T Combined Vaccine (PENTAXIM®) Given as a Three-Dose Primary Vaccination at 2, 3, and 4 Months of Age in Infants in China Completed NCT01491087 Phase 4
14 Safety and Immunogenicity of DAPTACEL® (CP10/5/5/3DT Aventis Pasteur 5-component Pertussis Vaccine in Combination With Tetanus and Diphtheria Toxoids Adsorbed) Administered as a 5th Dose in 4 to 6-Year-Old Children Previously Immunized With PENTACEL™ (HCP20/20/5/3DT-mIPV//PRP-T) Completed NCT00802867 Phase 4
15 A Phase IV, Single-blind, Randomized, Controlled, Monocentric Study to Assess the Interchangeability of Quinvaxem (DTwP-HepB-Hib) as the 2nd and 3rd Dose After Initial Vaccination With Tritanrix HB+Hib (DTwP-HepB/Hib) With Respect to Safety and Immunogenicity in Healthy Infants at 6, 10 and 14 Weeks of Age Completed NCT01357720 Phase 4
16 Assessment of Long-term Antibody Persistence After a Booster Dose of GSK Biologicals' Hib & Meningococcal C Vaccine (Menitorix™) 811936 Given at 12-15 Months of Age to Subjects Primed With 3 Doses of Menitorix™ at 2, 3, 4 Months of Age Completed NCT00454987 Phase 4
17 Immunogenicity and Safety Study of GSK Biologicals' Combined Diphtheria-tetanus-acellular Pertussis-hepatitis B-inactivated Polio-virus and Haemophilus Influenzae Type b Vaccine (Infanrix Hexa™) (217744) in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery Completed NCT02422264 Phase 4 Prevnar13
18 An Open-Label Multi-Center Study of Eculizumab in Children and Adolescents With a Diagnosis of Paroxysmal Nocturnal Hemoglobinuria Completed NCT00867932 Phase 4 Eculizumab
19 A Randomised Controlled Trial of Pneumococcal Conjugate Vaccines Synflorix and Prevenar13 in Sequence or Alone in High-risk Indigenous Infants (PREV-IX_COMBO): Immunogenicity, Carriage and Otitis Media Outcomes Completed NCT01174849 Phase 4 Synflorix;Prevenar13;COMBO
20 A Phase IV Study to Evaluate the Primary and Booster Immune Responses of UK Infants Receiving a Licensed 6-in-1 DTaP/IPV/Hib/HBV Vaccine (Infanrix-HexaTM) With a 13-valent Pneumococcal Conjugate Vaccine and Incorporating a Randomisation Study of a Single Dose of 3 Different Meningococcal Group C Conjugate Vaccines at 3 Months of Age Completed NCT01896596 Phase 4
21 Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life Completed NCT02258763 Phase 4 Amoxicillin-Potassium Clavulanate Combination;Placebo
22 Randomized, Controlled Clinical Trial of Day-care Based and Hospitalized Management of Severe and Very Severe Pneumonia, With Severe Malnutrition, With/Without Associated Co-morbidities in Children Completed NCT00968370 Phase 4
23 Efficacy of Antimicrobials in Young Children With Acute Otitis Media (AOM) Completed NCT00377260 Phase 4 amoxicillin-clavulanate;Placebo
24 A Randomised Controlled Trial Comparing Two-Dose Priming With the 10-Valent Pneumococcal Conjugate Vaccine at 6 and 10 Weeks to 6 and 14 Weeks in Nepali Children Completed NCT02385513 Phase 4
25 INvestigating COPD Outcomes, Genomics and Neutrophilic Inflammation With Tiotropium and Olodaterol Recruiting NCT03152149 Phase 4 Tiotropium & olodaterol;fluticasone furoate & vilanterol
26 Temocillin Pharmacokinetics in Paediatrics Recruiting NCT02260102 Phase 4 Temocillin
27 Pneumococcal Conjugate Vaccine (PCV) Schedules for the Northern Territory (NT): Randomised Controlled Trial of Booster Vaccines to Broaden and Strengthen Protection From Invasive and Mucosal Infections. Active, not recruiting NCT01735084 Phase 4
28 Vaccinating Children After Chemotherapy for Acute Lymphoblastic Leukemia: A Canadian Immunization Research Network Study Active, not recruiting NCT02447718 Phase 4
29 Babies Born Early Antibody Response to Men B Vaccination: A Phase IV Multicentre Randomised Study to Evaluate the Primary and Booster Immune Responses in UK Preterm Infants Receiving Routine Immunisations and Incorporating a Three Dose Versus a Two Dose Schedule of 4CMenB (Bexsero®) for Primary Immunisation. Active, not recruiting NCT03125616 Phase 4
30 Investigating the Mechanism of Inhaled Corticosteroids Associated Pneumonia by Longitudinal Characterisation of the Airway Microbiome in Patients With Severe COPD Active, not recruiting NCT02972476 Phase 4 Budesonide & formoterol fumarate and Aclidinium bromide;Fluticasone 500 & salmeterol and Aclidinium bromide;Fluticasone 250 & salmeterol and Aclidinium bromide;Aclidinium bromide & formoterol fumarate
31 A Prospective, Open-label, Interventional Phase IV Study to Assess the Safety of EupentaTM Inj. {Fully Liquid Pentavalent Vaccine, Adsorbed Diphtheria-Tetanus-whole-cell Pertussis-Hepatitis B (rDNA [Recombinant-deoxyribonucleic Acid])-Haemophilus Influenzae Type b Conjugate Vaccine} Not yet recruiting NCT04056728 Phase 4
32 A Phase IV, Non-Inferiority, Observer Blind, Randomized Clinical Study Comparing Safety And Immunogenicity Of DTP-HB-Hib Vaccination by Disposable-Syringe Jet Injector To Vaccination By Needle And Syringe In Healthy Infants In India Terminated NCT02409095 Phase 4
33 Assessment of Antibody Responses in UK Infants Given Two Doses of 10 or 13 Valent Pneumococcal Conjugate Vaccine (PCV) in Infancy and PCV13 in the Second Year of Life (Study Code: Pneumococcal in New Combinations (PINC)) Withdrawn NCT02918708 Phase 4
34 A Phase III, Double Blind, Parallel-controlled, Randomised Study to Evaluate the Safety and Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccine in Healthy Children 2 Months to 5 Years of Age Unknown status NCT02560272 Phase 3
35 A Phase III, Randomized, Double Blind, Placebo Controlled Trial to Evaluate the Protective Efficacy of Three Doses of Oral Rotavirus Vaccine (ORV) 116E, Against Severe Rotavirus Gastroenteritis in Infants Unknown status NCT01305109 Phase 3
36 An Open Label Trial of Azithromycin in Chronic Productive Cough Unknown status NCT02196493 Phase 3 Azithromycin
37 A Study of Safety and Immunogenicity of 10-valent and 13-valent Pneumococcal Conjugate Vaccines to Inform Policy Regarding Pneumococcal Vaccination of Papua New Guinean Children Unknown status NCT01619462 Phase 3
38 Randomized Study on Efficacy of Gemifloxacin-based Regimen for Helicobacter Pylori Infection Unknown status NCT02368470 Phase 3 Gemifloxacin-based triple therapy;Standard triple therapy
39 Randomized Controlled Trial Comparing Long and Short Duration of Antibiotic Prophylaxis for Patients Undergoing Sinus Lift Surgery Unknown status NCT02764710 Phase 3 Amoxicillin-Potassium Clavulanate Combination
40 A Single-blind, Randomized, Controlled, Multinational Study for the Evaluation of Safety of GlaxoSmithKline (GSK) Biologicals' Investigational Vaccination Regimen Compared to Monovalent Haemophilus Influenzae Type b (Hib) Control Vaccine in Healthy Infants at 2, 4, 6, and 12 to 15 Months of Age. Completed NCT00345579 Phase 3
41 Assessment of the Immunogenicity and Safety of Quinvaxem Vaccine (DTwP-HepB-Hib) Against Diphtheria, Pertussis, Tetanus, Hepatitis B and Diseases Caused by H. Influenzae Among Healthy Vietnamese Children Completed NCT01362517 Phase 3
42 A Phase III Open Label, Multi-Center Pediatric Study in China Comparing Booster Doses of Vaxem Hib and Hiberix Vaccines for the Prevention of Haemophilus Influenzae Type b (Hib) Infection Completed NCT01025544 Phase 3
43 Single-blind, Randomized, Controlled, Multinational Study for the Evaluation of Safety of GSK Biologicals' Hib-MenCY-TT Vaccine Compared to Monovalent Hib Control Vaccine in Healthy Infants at 2, 4, 6, and 12 to 15 Months of Age. Completed NCT00345683 Phase 3
44 Impact on Nasopharyngeal Carriage, Acute Otitis Media, Immunogenicity and Safety of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Completed NCT00839254 Phase 3
45 Evaluation of Effectiveness of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Against Invasive Disease Completed NCT00861380 Phase 3
46 A Phase III, Observer-blind, Randomized, Controlled, Multicenter Study to Investigate Immunogenicity and Safety of Haemophilus Influenzae Type b Vaccine in 2 - 4 Months Old Healthy Infants in China, According to the Recommended Regimen of 3 Intramuscular Doses Given One Month Apart Completed NCT00808392 Phase 3
47 A Phase III Observer Blind Single-Coordinating Center Pediatric Study in China Comparing a Booster Dose of Vaxem™ Hib to HIBERIX® When Given as Part of a Local Dosing Regimen in Infants Completed NCT01226953 Phase 3
48 A Phase IIIb, Controlled, Open Label, Single-Center, Persistency, Extension Study in Chinese Children After a 2+1 Dose Series of Either CRM197-Conjugate Haemophilus Influenzae Type b Vaccine or Tetanus Toxoid-Conjugate Haemophilus Influenzae Type b Vaccine Completed NCT02139228 Phase 3
49 A Multicentre, Comparative, Two-arm, Parallel-group, Double-blind, Randomized Phase III Study to Assess Immunogenicity and Safety of LBVH0101 (Haemophilus Influenzae Type b Tetanus Toxoid Conjugate Vaccine) Compared With Hiberix™ Vaccine in Healthy Infants at Two, Four and Six Months of Age Completed NCT01019772 Phase 3
50 A Phase III Observer-blind, Randomized, Controlled, Single-coordinating Center Study to Investigate Immunogenicity and Safety of a Monovalent Glycoprotein-conjugated (Diptheria Toxin -CRM197) Hib Vaccine in 13-59 Months Old Healthy Children in China, According to the Recommended Regimen of 1 Dose Completed NCT01125527 Phase 3

Search NIH Clinical Center for Haemophilus Influenzae

Genetic Tests for Haemophilus Influenzae

Anatomical Context for Haemophilus Influenzae

MalaCards organs/tissues related to Haemophilus Influenzae:

40
Testes, Lung, Colon, Tonsil, Neutrophil, B Cells, T Cells

Publications for Haemophilus Influenzae

Articles related to Haemophilus Influenzae:

(show top 50) (show all 18416)
# Title Authors PMID Year
1
Nasopharyngeal cultures in children; when, what and why? 61
31869625 2020
2
Effects of 10-valent pneumococcal conjugate (PCV10) vaccination on the nasopharyngeal microbiome. 61
31839468 2020
3
Routine Childhood Vaccines Given in the First 11 Months of Life. 61
31879133 2020
4
Licensure of a Diphtheria and Tetanus Toxoids and Acellular Pertussis, Inactivated Poliovirus, Haemophilus influenzae Type b Conjugate, and Hepatitis B Vaccine, and Guidance for Use in Infants. 61
32027629 2020
5
A systematic review and meta-analysis of predictors of airway intervention in adult epiglottitis. 61
31173373 2020
6
Evaluation of the impact of HIV-1 infection and density of common nasopharyngeal bacterial colonizers in South African children immunized with 7-valent pneumococcal conjugate vaccine. 61
31874779 2020
7
Conjugate vaccines dramatically reshaped the epidemiology of bacterial meningitis in a well-defined child population. 61
31365152 2020
8
Antibody response to vaccination after haematopoietic cell transplantation in children using a reduced dose schedule-A retrospective cohort study. 61
31617270 2020
9
Hepatitis B Birth Dose Effects on Childhood Immunization in the U.S. 61
31959321 2020
10
Coverage rates and timeliness of nationally recommended vaccinations in Swiss preschool children: A descriptive analysis using claims data. 61
31791812 2020
11
How are children who are delayed in the Childhood Vaccination Programme vaccinated: A nationwide register-based cohort study of Danish children aged 15-24 months and semi-structured interviews with vaccination providers. 61
30024308 2020
12
Bacterial infections in acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis. 61
31482316 2020
13
Invasive Haemophilus influenzae Type b Disease in the Post Hexavalent Era: Ten Years of Molecular Surveillance in Tuscany. 61
32032175 2020
14
Whole genome sequencing to study the phylogenetic structure of serotype a Haemophilus influenzae recovered from patients in Canada. 61
31661630 2020
15
Ultra-low dose rituximab for refractory pemghigus vulgaris: a pilot study. 61
32027810 2020
16
Bacterial Reservoirs in the Middle Ear of Otitis-prone Children Are Associated With Repeat Ventilation Tube Insertion. 61
31725550 2020
17
Impact of HIV status and vaccination schedule on bacterial nasopharyngeal carriage following infant immunisation with the pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine in South Africa. 61
32035706 2020
18
Clinical significance of viral-bacterial codetection among young children with respiratory tract infections: Findings of RSV, influenza, adenoviral infections. 61
31914021 2020
19
Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01E malaria vaccine in African children: a randomized trial. 61
31951771 2020
20
Exposure to lead and vaccine-specific IgG titers in South African children participating in the Venda Health Examination of Mothers, Babies and their Environment (VHEMBE): A longitudinal study. 61
31655331 2020
21
Cardiopulmonary Bypass and Infant Vaccination Titers. 61
31801853 2020
22
Comparative Clinical Evaluation of NeoPlex RB-8 with Seeplex PneumoBacter ACE for Simultaneous Detection of Eight Respiratory Bacterial Pathogens. 61
31748320 2020
23
Rapid and direct molecular detection of Streptococcus pneumoniae and Haemophilus influenzae isolated in oropharynx and nasal cavity of children. 61
32021693 2020
24
High Circulation of Malaria and Low Prevalence of Bacteremia in Febrile and Afebrile Children in Northeastern Gabon. 61
31769404 2020
25
Nasal delivery of a commensal Pasteurellaceae species inhibits nontypeable Haemophilus influenzae colonisation and delays onset of otitis media in mice. 61
31964748 2020
26
Inappropriate treatment of community-acquired pneumonia among children under five years of age in Tanzania. 61
31982627 2020
27
Effect of prior receipt of antibiotics on the pathogen distribution: a retrospective observational cohort study on 27,792 patients. 61
31906848 2020
28
Molecular epidemiology and evolution of Haemophilus influenzae. 61
31981610 2020
29
Comparison of Haemophilus influenzae Seroprevalence in Serum Samples Collected from 0- to 5-Year-Old Japanese Children in 1980, 1995, 2010, and 2012. 61
31474695 2020
30
Discovery of species-unique peptide biomarkers of bacterial pathogens by tandem mass spectrometry-based proteotyping. 61
31941798 2020
31
Comparative genomic analysis identifies X-factor (haemin)-independent Haemophilus haemolyticus: a formal re-classification of 'Haemophilus intermedius'. 61
31860436 2020
32
Rapid identification by MALDI-TOF/MS and antimicrobial disk diffusion susceptibility testing for positive blood cultures after a short incubation on the WASPLab. 61
31965365 2020
33
Monitoring of community-acquired pneumonia hospitalisations before the introduction of pneumococcal conjugate vaccine into Polish National Immunisation Programme (2009-2016): A nationwide retrospective database analysis. 61
31653527 2020
34
Enhancing Immunization Rates in Two Urban Academic Primary Care Clinics: A Before and After Assessment. 61
32002447 2020
35
Purpura Fulminans: a Rare but Fierce Presentation of Pneumococcal Sepsis. 61
32015972 2020
36
Infective endocarditis caused by non-typeable Haemophilus influenzae. 61
31880034 2020
37
Vaccine-preventable meningitis in French children with incorrect vaccination status from 2011 to 2013. 61
31776077 2020
38
Hypoxia-inducible factor and bacterial infections in chronic obstructive pulmonary disease. 61
31663668 2020
39
Decreased expression of a phagocytic receptor Siglec-1 on alveolar macrophages in chronic obstructive pulmonary disease. 61
31992280 2020
40
Haemophilus influenzae glucose catabolism leading to production of the immunometabolite acetate has a key contribution to the host airway-pathogen interplay. 61
31933358 2020
41
E1021K Homozygous Mutation in PIK3CD Leads to Activated PI3K-Delta Syndrome 1. 61
31953711 2020
42
First outbreak of Haemophilus influenzae clone ST422 with low susceptibility to quinolones in paediatric patients in Japan. 61
31961789 2020
43
Immunization Adherence in Children With Sickle Cell Disease: A Single-Institution Experience. 61
31897074 2020
44
Phase-Variable Glycosylation in Nontypeable Haemophilus influenzae. 61
31774288 2020
45
A competence-regulated toxin-antitoxin system in Haemophilus influenzae. 61
31931516 2020
46
Role of Horizontal Gene Transfer in the Development of Multidrug Resistance in Haemophilus influenzae. 61
31996416 2020
47
Characterization of biofilm formation and induction of apoptotic DNA fragmentation by nontypeable Haemophilus influenzae on polarized human airway epithelial cells. 61
31968224 2020
48
Fluoroquinolone resistance in Haemophilus influenzae from nursing home residents in Taiwan: correlation of MICs and mutations in QRDRs. 61
31951091 2020
49
Immunological characterisation of truncated lipooligosaccharide-outer membrane protein based conjugate vaccine against Moraxella catarrhalis and nontypeable Haemophilus influenzae. 61
31668366 2020
50
Transcutaneous immunization with a nontypeable Haemophilus influenzae dual adhesin-directed immunogen induces durable and boostable immunity. 61
32001071 2020

Variations for Haemophilus Influenzae

Expression for Haemophilus Influenzae

Search GEO for disease gene expression data for Haemophilus Influenzae.

Pathways for Haemophilus Influenzae

Pathways related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

(show all 14)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.05 TNF TLR2 CXCL8
2 12.01 VTN TNF TLR2
3
Show member pathways
11.97 TNF TLR2 CXCL8
4 11.93 TNF TLR2 CLEC7A
5
Show member pathways
11.88 TNF TLR2 CXCL8
6
Show member pathways
11.83 TNF TLR2 CXCL8
7 11.79 TNF TF CXCL8
8 11.51 TNF TLR2 CXCL8
9 11.4 TNF TLR2 CXCL8
10 11.26 VTN TLR2 CLEC7A
11 10.89 TNF TLR2 CXCL8
12 10.86 TNF CXCL8
13 10.65 TNF CXCL8
14 10.5 TNF TLR2 CXCL8

GO Terms for Haemophilus Influenzae

Cellular components related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.63 VTN TNF TF LTF CXCL8 CFH
2 blood microparticle GO:0072562 9.13 VTN TF CFH
3 cell surface GO:0009986 9.02 TNF TLR2 TF LTF CLEC7A

Biological processes related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

(show all 16)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.76 VTN TNF TLR2 CXCL8
2 iron ion homeostasis GO:0055072 9.56 TF LTF
3 positive regulation of interleukin-6 secretion GO:2000778 9.55 TNF TLR2
4 lipopolysaccharide-mediated signaling pathway GO:0031663 9.54 TNF TLR2
5 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.54 TNF TLR2 LTF
6 osteoclast differentiation GO:0030316 9.52 TNF TF
7 microglial cell activation GO:0001774 9.51 TNF TLR2
8 positive regulation of interleukin-8 production GO:0032757 9.49 TNF TLR2
9 positive regulation of receptor-mediated endocytosis GO:0048260 9.48 VTN TF
10 positive regulation of wound healing GO:0090303 9.43 VTN CLEC7A
11 positive regulation of chemokine production GO:0032722 9.4 TNF TLR2
12 embryonic digestive tract development GO:0048566 9.32 TNF CXCL8
13 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.26 TNF CLEC7A
14 inflammatory response GO:0006954 9.26 TNF TLR2 CXCL8 CLEC7A
15 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.16 TNF CLEC7A
16 response to molecule of bacterial origin GO:0002237 8.62 TLR2 CXCL8

Molecular functions related to Haemophilus Influenzae according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lipopolysaccharide binding GO:0001530 9.16 TLR2 LTF
2 heparin binding GO:0008201 9.13 VTN LTF CFH
3 signaling pattern recognition receptor activity GO:0008329 8.62 TLR2 CLEC7A

Sources for Haemophilus Influenzae

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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